phenyl-n-tert-butylnitrone and acetylcysteine

phenyl-n-tert-butylnitrone has been researched along with acetylcysteine in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (44.44)18.2507
2000's8 (44.44)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bartolomé, B; Chioua, M; García, AG; Garrido, I; González-Lafuente, L; Ismaili, L; Marco-Contelles, J; Oset-Gasque, MJ; Revuelta, J; Samadi, A; Soriano, E; Tomassolli, I; Valderas, C; Villarroya, M1
Castagné, V; Clarke, PG1
Brenner, B; Coggeshall, KM; Gulbins, E; Heinle, H; Koppenhoefer, U; Lang, F; Linderkamp, O; Schlottmann, K; Welsch, J1
Hayase, Y; Kashiwakura, I; Kuwabara, M; Murakami, M; Takagi, Y1
Busciglio, J; Gabuzda, D; Lorenzo, A; Raina, J; Shi, B1
Floyd, RA; Hensley, K; Kenney, L; Nguyen, X; Pye, QN; Robinson, KA; Salzman, S; Stewart, CA1
Floyd, RA; Hensley, K; Pye, Q; Robinson, KA; Stewart, CA1
Bedker, DA; Castagné, V; Clarke, PG; Lefèvre, K; Natero, R1
Bray, TM; Chen, G; Ho, E1
Floyd, RA; Graham, KL; Kotake, Y; Tabatabaie, T; Vasquez, AM1
Inanami, O; Kuwabara, M; Tsuji, M1
Banic, S; Bifrare, YD; Christen, S; Leib, SL; Lykkesfeldt, J; Schaper, M; Siegenthaler, C; Täuber, MG1
Lee, JH; Park, JE; Park, JW; Yang, ES; Yang, JH; Yoon, SJ1
Chen, YH; Sun, MF; Wang, H; Wang, JP; Wei, LZ; Wei, W; Xu, DX1
Lin, HC; Shiah, IS; Tung, CS; Wan, FJ1
Dane, S; Goettl, VM; Hacimuftuoglu, A; Handy, CR; Lin, CG; Stephens, RL1
Bowden, GT; Chen, QM; Sun, H; Tu, VC1
Chen, LH; Cheng, RX; Gao, YJ; Huang, Y; Liu, T; Liu, TT; Wang, S; Wang, XL; Zhou, FM; Zhou, Y1

Other Studies

18 other study(ies) available for phenyl-n-tert-butylnitrone and acetylcysteine

ArticleYear
Synthesis, structure, theoretical and experimental in vitro antioxidant/pharmacological properties of α-aryl, N-alkyl nitrones, as potential agents for the treatment of cerebral ischemia.
    Bioorganic & medicinal chemistry, 2011, Jan-15, Volume: 19, Issue:2

    Topics: Antioxidants; Brain Ischemia; Cell Line, Tumor; Humans; Hydrogen Bonding; Hydroxyl Radical; Models, Theoretical; Nitrogen Oxides; Reactive Oxygen Species; Thermodynamics

2011
Axotomy-induced retinal ganglion cell death in development: its time-course and its diminution by antioxidants.
    Proceedings. Biological sciences, 1996, Sep-22, Volume: 263, Issue:1374

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Axons; Chick Embryo; Cyclic N-Oxides; Embryo, Nonmammalian; Free Radical Scavengers; Glutathione; Nitrogen Oxides; Oxidative Stress; Retinal Ganglion Cells; Time Factors

1996
Fas-induced programmed cell death is mediated by a Ras-regulated O2- synthesis.
    Immunology, 1996, Volume: 89, Issue:2

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Cyclic N-Oxides; fas Receptor; Gene Expression Regulation; Humans; Jurkat Cells; Nitrogen Oxides; Oncogene Protein p21(ras); Reactive Oxygen Species; Transfection

1996
Effects of alpha-phenyl N-tert-butylnitrone, a spin trap reagent, on the proliferation of murine hematopoietic progenitor cells in vitro.
    Research communications in molecular pathology and pharmacology, 1997, Volume: 98, Issue:1

    Topics: Acetylcysteine; Animals; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay; Cyclic N-Oxides; Glutathione; Glutathione Disulfide; Hematopoietic Stem Cells; Interleukin-3; Interleukin-6; Male; Mice; Nitrogen Oxides; Spin Labels; Stem Cell Factor

1997
Neuronal apoptosis induced by HIV-1 Tat protein and TNF-alpha: potentiation of neurotoxicity mediated by oxidative stress and implications for HIV-1 dementia.
    Journal of neurovirology, 1998, Volume: 4, Issue:3

    Topics: Acetylcysteine; AIDS Dementia Complex; Apoptosis; Biotin; Brain; Catalase; Cells, Cultured; Cyclic N-Oxides; Deoxyuracil Nucleotides; DNA Fragmentation; Fetus; Free Radical Scavengers; Gene Products, tat; HIV-1; Humans; Neurons; Nitrogen Oxides; Oxidative Stress; Staining and Labeling; Superoxide Dismutase; tat Gene Products, Human Immunodeficiency Virus; Tumor Necrosis Factor-alpha

1998
Redox-sensitive protein phosphatase activity regulates the phosphorylation state of p38 protein kinase in primary astrocyte culture.
    Journal of neuroscience research, 1999, Mar-15, Volume: 55, Issue:6

    Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Astrocytes; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cerebral Cortex; Cyclic N-Oxides; Hydrogen Peroxide; Interleukin-1; Kinetics; Mitogen-Activated Protein Kinases; Nitrogen Oxides; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Phosphoprotein Phosphatases; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sorbitol; Spin Labels

1999
Basal protein phosphorylation is decreased and phosphatase activity increased by an antioxidant and a free radical trap in primary rat glia.
    Archives of biochemistry and biophysics, 1999, May-15, Volume: 365, Issue:2

    Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cerebral Cortex; Cyclic N-Oxides; Enzyme Activation; Free Radical Scavengers; Hydrogen Peroxide; Kinetics; Nerve Tissue Proteins; Neuroglia; Nitrogen Oxides; Phosphoprotein Phosphatases; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction

1999
An optimal redox status for the survival of axotomized ganglion cells in the developing retina.
    Neuroscience, 1999, Volume: 93, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Axotomy; Azulenes; Cell Count; Cell Survival; Chick Embryo; Cyclic N-Oxides; Eye; Neuroprotective Agents; Nitrogen Oxides; Oxidation-Reduction; Oxidative Stress; Retina; Retinal Degeneration; Retinal Ganglion Cells; Sesquiterpenes; Thiourea

1999
Supplementation of N-acetylcysteine inhibits NFkappaB activation and protects against alloxan-induced diabetes in CD-1 mice.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1999, Volume: 13, Issue:13

    Topics: Acetylcysteine; Administration, Oral; Alloxan; Animals; Blood Glucose; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Male; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen Oxides; Pancreas

1999
Inhibition of the cytokine-mediated inducible nitric oxide synthase expression in rat insulinoma cells by phenyl N-tert-butylnitrone.
    Nitric oxide : biology and chemistry, 2000, Volume: 4, Issue:2

    Topics: Acetylcysteine; Animals; Blotting, Northern; Cell Survival; Cyclic N-Oxides; Cytokines; Diabetes Mellitus, Type 1; Enzyme Induction; Enzyme Inhibitors; Free Radical Scavengers; Immunoblotting; Insulinoma; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitrogen Oxides; Protective Agents; Rats; RNA, Messenger; Thioctic Acid; Tumor Cells, Cultured

2000
Induction of neurite outgrowth in PC12 cells by alpha -phenyl-N-tert-butylnitron through activation of protein kinase C and the Ras-extracellular signal-regulated kinase pathway.
    The Journal of biological chemistry, 2001, Aug-31, Volume: 276, Issue:35

    Topics: Acetylcysteine; Androstadienes; Animals; Cyclic N-Oxides; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Indoles; Isoquinolines; Kinetics; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Neurites; Neuroprotective Agents; Nitrogen Oxides; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Protein Kinase C; ras Proteins; Rats; Recombinant Proteins; Signal Transduction; Sulfonamides; Transfection; Wortmannin

2001
Oxidative stress in brain during experimental bacterial meningitis: differential effects of alpha-phenyl-tert-butyl nitrone and N-acetylcysteine treatment.
    Free radical biology & medicine, 2001, Sep-15, Volume: 31, Issue:6

    Topics: Acetylcysteine; Animals; Brain; Cerebrospinal Fluid; Cyclic N-Oxides; Disease Models, Animal; Female; Free Radical Scavengers; Glutathione; Meningitis, Pneumococcal; Nitrogen Oxides; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Streptococcus pneumoniae

2001
Lipid peroxidation-mediated cytotoxicity and DNA damage in U937 cells.
    Biochimie, 2002, Volume: 84, Issue:12

    Topics: Acetylcysteine; Amidines; Catalase; Cell Survival; Cyclic N-Oxides; DNA Damage; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Humans; Lipid Peroxidation; Microscopy, Confocal; NADP; Nitrogen Oxides; Oxidants; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; tert-Butylhydroperoxide; Time Factors; U937 Cells

2002
Lipopolysaccharide treatment downregulates the expression of the pregnane X receptor, cyp3a11 and mdr1a genes in mouse placenta.
    Toxicology, 2005, Aug-01, Volume: 211, Issue:3

    Topics: Acetylcysteine; Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Cyclic N-Oxides; Cytochrome P-450 CYP3A; Down-Regulation; Female; Free Radical Scavengers; Glutathione; Lipopolysaccharides; Male; Membrane Proteins; Mice; Mice, Inbred ICR; Nitrogen Oxides; Oxidoreductases, N-Demethylating; Placenta; Pregnancy; Pregnane X Receptor; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiobarbituric Acid Reactive Substances

2005
Effects of alpha-phenyl-N-tert-butyl nitrone and N-acetylcysteine on hydroxyl radical formation and dopamine depletion in the rat striatum produced by d-amphetamine.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2006, Volume: 16, Issue:2

    Topics: Acetylcysteine; Animals; Body Temperature; Cyclic N-Oxides; Dextroamphetamine; Dopamine; Dopamine Uptake Inhibitors; Free Radical Scavengers; Hydroxybenzoates; Hydroxyl Radical; Lipid Peroxidation; Male; Microdialysis; Neostriatum; Neuroprotective Agents; Neurotoxicity Syndromes; Nitrogen Oxides; Pilot Projects; Rats; Rats, Sprague-Dawley

2006
Antioxidants attenuate multiple phases of formalin-induced nociceptive response in mice.
    Behavioural brain research, 2006, Oct-16, Volume: 173, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Behavior, Animal; Cyclic N-Oxides; Female; Formaldehyde; Injections, Spinal; Male; Mice; Nitrogen Oxides; Pain; Pain Measurement; Spin Labels; Time Factors

2006
Involvement of oxidants and AP-1 in angiotensin II-activated NFAT3 transcription factor.
    American journal of physiology. Cell physiology, 2007, Volume: 292, Issue:4

    Topics: Acetylcysteine; Angiotensin II; Animals; Animals, Newborn; Antioxidants; Catalase; Cell Enlargement; Cells, Cultured; Cyclic N-Oxides; Enzyme Activation; Hydrogen Peroxide; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; NFATC Transcription Factors; Oxidants; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Signal Transduction; Thioctic Acid; Transcription Factor AP-1

2007
Antioxidants Attenuate Acute and Chronic Itch: Peripheral and Central Mechanisms of Oxidative Stress in Pruritus.
    Neuroscience bulletin, 2017, Volume: 33, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Cell Line, Transformed; Central Nervous System; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Male; Malondialdehyde; Mice; Oxidative Stress; p-Methoxy-N-methylphenethylamine; Peripheral Nerves; Pruritus; Reactive Oxygen Species; Skin; Superoxide Dismutase; Time Factors

2017