phenyl-n-tert-butylnitrone and 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid

phenyl-n-tert-butylnitrone has been researched along with 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (21.43)18.2507
2000's6 (42.86)29.6817
2010's5 (35.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Balogh, GT; Fischer, J; Gere, A; Kis-Varga, A; Könczöl, A; Vukics, K1
Böker, J; Durand, G; Hardeland, R; Ortial, S; Pappolla, MA; Poeggeler, B; Polidori, A; Pucci, B1
Bartolomé, B; Chioua, M; García, AG; Garrido, I; González-Lafuente, L; Ismaili, L; Marco-Contelles, J; Oset-Gasque, MJ; Revuelta, J; Samadi, A; Soriano, E; Tomassolli, I; Valderas, C; Villarroya, M1
Alcázar, A; Ayuso, I; Chioua, M; González, MP; Hadjipavlou-Litina, D; Marco-Contelles, J; Monjas, L; Oset-Gasque, MJ; Rodríguez-Franco, MI; Samadi, A; Soriano, E; Sucunza, D1
Asteian, A; Cassien, M; Culcasi, M; Kandouli, C; Mercier, A; Petrocchi, C; Pietri, S; Ricquebourg, E; Robin, M; Rockenbauer, A; Thétiot-Laurent, S1
Cutler, R; Denisova, N; Erat, S; Joseph, JA; Strain, J; Villalobos-Molina, R1
Fisher, D; Jimenez, ND; Joseph, JA; Strain, JG1
Aksenov, MY; Aksenova, MV; Butterfield, DA; Carney, JM; Cole Harper, P; DeAtley, SM; Hadley, R; Harris, B1
Bär, DP; de Smet, M; de With, MC; Kon, M; Kroese, AB; van der Heijden, EP; Werker, PM1
Bachratá, K; Horáková, L; Ondrejicková, O; Vajdová, M1
Allen, JW; Aschner, M; Mutkus, LA1
Aschner, M; Shanker, G1
Bacskai, BJ; Borrelli, LA; Garcia-Alloza, M; Hyman, BT1
Cuevas, J; Katnik, C1

Other Studies

14 other study(ies) available for phenyl-n-tert-butylnitrone and 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid

ArticleYear
Nitrone derivatives of trolox as neuroprotective agents.
    Bioorganic & medicinal chemistry letters, 2005, Jun-15, Volume: 15, Issue:12

    Topics: Animals; Antioxidants; Arterial Occlusive Diseases; Brain Ischemia; Cerebrovascular Circulation; Chromans; Free Radical Scavengers; Hydroxyl Radical; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Mice; Neuroprotective Agents; Nitrogen Oxides; Structure-Activity Relationship

2005
Fluorinated amphiphilic amino acid derivatives as antioxidant carriers: a new class of protective agents.
    Journal of medicinal chemistry, 2006, May-04, Volume: 49, Issue:9

    Topics: Amino Acids; Animals; Antioxidants; Cell Death; Cells, Cultured; Chemical Phenomena; Chemistry, Physical; Doxorubicin; Fluorine; Hydrogen Peroxide; Molecular Structure; Oxidation-Reduction; Protective Agents; Surface-Active Agents

2006
Synthesis, structure, theoretical and experimental in vitro antioxidant/pharmacological properties of α-aryl, N-alkyl nitrones, as potential agents for the treatment of cerebral ischemia.
    Bioorganic & medicinal chemistry, 2011, Jan-15, Volume: 19, Issue:2

    Topics: Antioxidants; Brain Ischemia; Cell Line, Tumor; Humans; Hydrogen Bonding; Hydroxyl Radical; Models, Theoretical; Nitrogen Oxides; Reactive Oxygen Species; Thermodynamics

2011
Α-aryl-N-alkyl nitrones, as potential agents for stroke treatment: synthesis, theoretical calculations, antioxidant, anti-inflammatory, neuroprotective, and brain-blood barrier permeability properties.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Blood-Brain Barrier; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Edema; Female; Free Radical Scavengers; Hydroxyl Radical; Lipid Peroxidation; Lipoxygenase Inhibitors; Male; Necrosis; Neurons; Neuroprotective Agents; Nitric Oxide Donors; Nitrogen Oxides; Oximes; Permeability; Quinolines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Stereoisomerism; Stroke; Structure-Activity Relationship; Superoxides

2012
On the vasoprotective mechanisms underlying novel β-phosphorylated nitrones: Focus on free radical characterization, scavenging and NO-donation in a biological model of oxidative stress.
    European journal of medicinal chemistry, 2016, Aug-25, Volume: 119

    Topics: Animals; Aorta; Biphenyl Compounds; Cattle; Cell Line, Tumor; Free Radical Scavengers; Free Radicals; Hydrophobic and Hydrophilic Interactions; Nitric Oxide; Nitrogen Oxides; Oxidative Stress; Phosphorylation; Picrates; Protein Carbonylation; Rats; Spin Trapping; Superoxides; Vasodilation

2016
Age differences in sensitivity to H2O2- or NO-induced reductions in K(+)-evoked dopamine release from superfused striatal slices: reversals by PBN or Trolox.
    Free radical biology & medicine, 1996, Volume: 20, Issue:6

    Topics: Aging; Animals; Antioxidants; Chromans; Cyclic N-Oxides; Dopamine; Free Radicals; Glutathione; Hydrogen Peroxide; In Vitro Techniques; Lipid Peroxidation; Nitric Oxide; Nitrogen Oxides; Nitroprusside; Potassium; Rats; Rats, Inbred F344; Visual Cortex

1996
Oxidant injury in PC12 cells--a possible model of calcium "dysregulation" in aging: I. Selectivity of protection against oxidative stress.
    Journal of neurochemistry, 1997, Volume: 69, Issue:3

    Topics: Aging; Animals; Antioxidants; Calcium; Cell Survival; Chromans; Cyclic N-Oxides; Dose-Response Relationship, Drug; Hydrogen Peroxide; Kinetics; Models, Neurological; Nifedipine; Nitrogen Oxides; Oxidative Stress; PC12 Cells; Rats; Time Factors

1997
Antioxidants protect against reactive oxygen species associated with adriamycin-treated cardiomyocytes.
    Cancer letters, 1999, Feb-08, Volume: 136, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Chromans; Cyclic N-Oxides; Dose-Response Relationship, Drug; Doxorubicin; Fluoresceins; Heart; Mesalamine; Myocardium; Nitrogen Oxides; Oxidative Stress; Rats; Reactive Oxygen Species

1999
Improving the preservation of isolated rat skeletal muscles stored for 16 hours at 4 degrees C.
    Transplantation, 2000, Apr-15, Volume: 69, Issue:7

    Topics: Animals; Antioxidants; Chelating Agents; Chromans; Cryopreservation; Cyclic N-Oxides; Deferoxamine; Diacetyl; Drug Combinations; Electric Stimulation; Energy Metabolism; Glucose; Male; Mannitol; Muscle Contraction; Muscle, Skeletal; Nitrogen Oxides; Oxygen; Potassium Chloride; Procaine; Rats; Rats, Wistar; Time Factors

2000
Preventive effect of several antioxidants after oxidative stress on rat brain homogenates.
    General physiology and biophysics, 2000, Volume: 19, Issue:2

    Topics: Animals; Antioxidants; Benzenesulfonates; Brain; Brain Injuries; Butylated Hydroxytoluene; Carbolines; Chromans; Creatine Kinase; Cyclic N-Oxides; Inhibitory Concentration 50; Lipid Peroxidation; Male; Melatonin; Methylprednisolone; Models, Chemical; Neuroprotective Agents; Nitrogen Oxides; Oxidative Stress; Oxygen; Pregnatrienes; Rats; Rats, Wistar; Serotonin; Thiobarbituric Acid Reactive Substances

2000
Methylmercury-mediated inhibition of 3H-D-aspartate transport in cultured astrocytes is reversed by the antioxidant catalase.
    Brain research, 2001, May-25, Volume: 902, Issue:1

    Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Antioxidants; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Biological Transport; Catalase; Cattle; Cells, Cultured; Chromans; Cyclic N-Oxides; Dinitrobenzenes; Dithiothreitol; Hydrogen Peroxide; Methylmercury Compounds; Nerve Tissue Proteins; Nitrogen Oxides; Oxidants; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reducing Agents; RNA, Messenger; Spin Labels

2001
Methylmercury-induced reactive oxygen species formation in neonatal cerebral astrocytic cultures is attenuated by antioxidants.
    Brain research. Molecular brain research, 2003, Jan-31, Volume: 110, Issue:1

    Topics: Animals; Animals, Newborn; Antioxidants; Arachidonic Acids; Astrocytes; Cells, Cultured; Chromans; Cyclic N-Oxides; Enzyme Inhibitors; Glutathione; Methylmercury Compounds; Neuroprotective Agents; Nitrogen Oxides; Propyl Gallate; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase

2003
Antioxidants have a rapid and long-lasting effect on neuritic abnormalities in APP:PS1 mice.
    Neurobiology of aging, 2010, Volume: 31, Issue:12

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antioxidants; Chromans; Cyclic N-Oxides; Disease Models, Animal; Free Radical Scavengers; Ginkgo biloba; Mice; Mice, Transgenic; Oxidative Stress; Plant Extracts; Plaque, Amyloid; Presenilin-1; Time Factors

2010
Non-specific inhibition of ischemia- and acidosis-induced intracellular calcium elevations and membrane currents by α-phenyl-N-tert-butylnitrone, butylated hydroxytoluene and trolox.
    International journal of molecular sciences, 2014, Feb-27, Volume: 15, Issue:3

    Topics: Acids; Animals; Antioxidants; Azides; Butylated Hydroxytoluene; Calcium; Cells, Cultured; Cerebral Cortex; Chromans; Cyclic N-Oxides; Fluorometry; Fura-2; Hydrogen-Ion Concentration; Intracellular Space; Membrane Potentials; Neurons; Rats

2014