phenyl-n-tert-butylnitrone and 5,5-dimethyl-1-pyrroline-1-oxide

phenyl-n-tert-butylnitrone has been researched along with 5,5-dimethyl-1-pyrroline-1-oxide in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19904 (9.52)18.7374
1990's25 (59.52)18.2507
2000's10 (23.81)29.6817
2010's3 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hideg, E; Hideg, K; Sár, CP; Vass, I1
Barriga, G; Castro, A; Cerecetto, H; Gerpe, A; González, M; Norambuena, E; Olea-Azar, C; Porcal, W1
Akaike, T; Ishimatsu, A; Maeda, H; Muramatsu, T; Oda, T; Sato, K; Takeshita, S1
Gantchev, TG1
Cova, D; De Angelis, L; Monti, E; Piccinini, F1
Agnati, LF; Grimaldi, R; Tomasi, A; Vannini, V; Zini, I1
Hou, JW; Xin, WJ; Yan, LJ; Zhao, BL1
Monti, E; Paracchini, L; Perletti, G; Piccinini, F1
Janzen, EG1
Bracciotti, G; Falsini, S; Novelli, GP1
Graceffa, P1
DuBose, CM; Floyd, RA; Poyer, JL; Wong, PK1
Connor, HD; Mason, RP; Mottley, C1
Stern, A; Thornalley, PJ1
Hague, CM; McCay, PB; Moore, DR; Reinke, LA1
Floyd, RA; Tabatabaie, T1
Knecht, KT; Mason, RP1
Augusto, O; Gatti, RM; Radi, R1
De Bono, D; Symons, MC; Yang, WD1
Hiramoto, K; Johkoh, H; Kikugawa, K; Sako, K1
Anderson, DE; Rosen, GM; Rubin, LJ; Tod, ML; Tseng, CM; Yuan, XJ1
Downs, PE; DuBose, CM; Janzen, EG; Poyer, JL; Schaefer, CF1
Miura, Y; Ozawa, T; Ueda, J1
Endre, ZH; Hanson, GR; Kadkhodaee, M; Towner, RA1
Beal, MF; Henshaw, DR; MacGarvey, U; Schulz, JB1
Janzen, EG; Kosanke, SD; Poyer, JL; Schaefer, CF; West, MS1
Gannett, PM; Kolar, C; Lawson, T; Shi, X; Toth, B1
Dorey, G; Nepveu, F; Rolland, Y; Souchard, JP; Spedding, M1
Ali, MA; Konishi, T1
Kotake, Y; Lee, M; Liu, KJ; Miyake, M; Sugden, K; Swartz, HM; Yu, Z1
Symons, MC1
Bunik, VI; Sievers, C1
Blasiak, J; Woźniak, K1
Haire, DL; Hrvoic, I; Janzen, EG; Robinson, VJ1
Brezová, V; Dobrota, D; Horecký, J; Kasparová, S; Liptaj, T; Mlynárik, V; Ulicná, O; Valko, M; Vancová, O1
Chen, TF; Chou, DS; Hsiao, G; Shen, MY; Sheu, JR; Tsai, YJ1
Iannone, A; Liverani, L; Mascellani, G; Rota, C; Spelta, F; Tomasi, A; Vismara, E1
Kotake, Y; Sueishi, Y; Yamamoto, S; Yoshioka, C; Yoshioka, D1
Chen, CS; Chen, SC; Hseu, YC; Kuo, JY; Liang, SH1
Bagryanskaya, EG; Khramtsov, VV; Plyusnin, VF; Polovyanenko, DN; Reznikov, VA1
Schlick, S; Spulber, M1
Das, A; Doseff, AI; Gopalakrishnan, B; Villamena, FA; Voss, OH1

Reviews

1 review(s) available for phenyl-n-tert-butylnitrone and 5,5-dimethyl-1-pyrroline-1-oxide

ArticleYear
In vivo detection of radical adducts by electron spin resonance.
    Methods in enzymology, 1994, Volume: 233

    Topics: Animals; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Humans; Hydroxyl Radical; Nitrogen Oxides; Spin Labels; Superoxides

1994

Other Studies

41 other study(ies) available for phenyl-n-tert-butylnitrone and 5,5-dimethyl-1-pyrroline-1-oxide

ArticleYear
Synthesis of alpha-aryl N-adamant-1-yl nitrones and using them for spin trapping of hydroxyl radicals.
    Bioorganic & medicinal chemistry letters, 1998, Feb-17, Volume: 8, Issue:4

    Topics: Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydroxyl Radical; Nitrogen Oxides; Spin Labels

1998
New heteroaryl nitrones with spin trap properties: Identification of a 4-furoxanyl derivative with excellent properties to be used in biological systems.
    Bioorganic & medicinal chemistry, 2010, Jan-15, Volume: 18, Issue:2

    Topics: Electron Spin Resonance Spectroscopy; Heterocyclic Compounds; Hydrogen-Ion Concentration; Kinetics; Microbial Sensitivity Tests; Molecular Structure; Nitrogen Oxides; Solubility; Stereoisomerism; Trypanosoma cruzi

2010
Hydroxyl radical generation by red tide algae.
    Archives of biochemistry and biophysics, 1992, Volume: 294, Issue:1

    Topics: Cyclic N-Oxides; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Ethanol; Free Radicals; Hydroxides; Hydroxyl Radical; Luminescent Measurements; Luminol; Nitrogen Oxides; Phytoplankton; Spin Labels; Superoxide Dismutase; Superoxides

1992
Spin-trapping of free radicals during phthalocyanine photosensitization of lymphoma cells in vitro.
    Cancer biochemistry biophysics, 1992, Volume: 13, Issue:2

    Topics: Burkitt Lymphoma; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Extracellular Space; Free Radicals; Humans; Indoles; Intracellular Fluid; Nitrogen Oxides; Organometallic Compounds; Photochemotherapy; Radiation-Sensitizing Agents; Spin Labels; Tumor Cells, Cultured

1992
Subcellular distribution of two spin trapping agents in rat heart: possible explanation for their different protective effects against doxorubicin-induced cardiotoxicity.
    Free radical research communications, 1992, Volume: 15, Issue:6

    Topics: Animals; Cyclic N-Oxides; Doxorubicin; Free Radicals; Heart; In Vitro Techniques; Male; Myocardium; Nitrogen Oxides; Rats; Spin Labels; Subcellular Fractions

1992
Detection of free radicals during brain ischemia and reperfusion by spin trapping and microdialysis.
    Neuroscience letters, 1992, Apr-27, Volume: 138, Issue:2

    Topics: Animals; Brain Ischemia; Cyclic N-Oxides; Dialysis; Free Radicals; Nitrogen Oxides; Pyridines; Rats; Rats, Inbred Strains; Reperfusion; Spin Labels; Thiobarbiturates

1992
ESR spin trapping studies on the free radicals in gasphase of cigarette smoking.
    Chinese medical journal, 1991, Volume: 104, Issue:7

    Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Nicotiana; Nitrogen Oxides; Plants, Toxic; Smoke; Spin Labels

1991
Protective effects of spin-trapping agents on adriamycin-induced cardiotoxicity in isolated rat atria.
    Free radical research communications, 1991, Volume: 14, Issue:1

    Topics: Animals; Cardiomyopathies; Cyclic N-Oxides; Depression, Chemical; Doxorubicin; Female; Free Radicals; Kinetics; Myocardial Contraction; Nitrogen Oxides; Pyridines; Rats; Rats, Inbred Strains; Spin Labels

1991
Spin trapping and associated vocabulary.
    Free radical research communications, 1990, Volume: 9, Issue:3-6

    Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Nitrogen Oxides; Spin Labels

1990
Spin-trappers and vitamin E prolong endurance to muscle fatigue in mice.
    Free radical biology & medicine, 1990, Volume: 8, Issue:1

    Topics: Animals; Cyclic N-Oxides; Fatigue; Free Radicals; Male; Mice; Nitrogen Oxides; Physical Endurance; Pyridines; Spin Labels; Swimming; Vitamin E

1990
Spin trapping the cysteine thiyl radical with phenyl-N-t-butylnitrone.
    Biochimica et biophysica acta, 1988, May-18, Volume: 954, Issue:2

    Topics: Cyclic N-Oxides; Cysteine; Electron Spin Resonance Spectroscopy; Nitrogen Oxides; Oxidation-Reduction; Spin Labels

1988
Hydralazine-dependent carbon dioxide free radical formation by metabolizing mitochondria.
    The Journal of biological chemistry, 1988, Aug-15, Volume: 263, Issue:23

    Topics: Animals; Antimycin A; Carbon Dioxide; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Female; Free Radicals; Hydralazine; Mitochondria, Liver; Nitrogen Oxides; Rats; Rats, Inbred F344; Spin Labels

1988
[17O]oxygen hyperfine structure for the hydroxyl and superoxide radical adducts of the spin traps DMPO, PBN and 4-POBN.
    Biochemical and biophysical research communications, 1986, Dec-15, Volume: 141, Issue:2

    Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Hydroxides; Nitrogen Oxides; Oxygen; Pyridines; Spin Labels; Superoxides

1986
The effect of nitrone spin trapping agents on red cell glucose metabolism.
    Free radical research communications, 1985, Volume: 1, Issue:2

    Topics: Adult; Blood Glucose; Cyclic N-Oxides; Erythrocytes; Glycolysis; Hemoglobins; Humans; In Vitro Techniques; Kinetics; Nitrogen Oxides; Spin Labels

1985
Metabolism of ethanol to 1-hydroxyethyl radicals in rat liver microsomes: comparative studies with three spin trapping agents.
    Free radical research, 1994, Volume: 21, Issue:4

    Topics: Animals; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Ethanol; Free Radicals; Male; Microsomes, Liver; Nitrogen Oxides; Pyridines; Rats; Rats, Sprague-Dawley; Spin Labels; Superoxide Dismutase

1994
Susceptibility of glutathione peroxidase and glutathione reductase to oxidative damage and the protective effect of spin trapping agents.
    Archives of biochemistry and biophysics, 1994, Volume: 314, Issue:1

    Topics: Animals; Ascorbic Acid; Cattle; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Erythrocytes; Ferric Compounds; Ferrous Compounds; Glutathione Peroxidase; Glutathione Reductase; Hydroxyl Radical; Light; Methylene Blue; Nitrogen Oxides; Oxidation-Reduction; Oxygen; Ozone; Singlet Oxygen; Spin Labels

1994
Peroxynitrite-mediated oxidation of albumin to the protein-thiyl free radical.
    FEBS letters, 1994, Jul-18, Volume: 348, Issue:3

    Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen-Ion Concentration; Nitrates; Nitrogen Oxides; Oxidation-Reduction; Serum Albumin, Bovine; Spin Labels

1994
The effect of myoglobin on the stability of the hydroxyl-radical adducts of 5,5 dimethyl-1-pyrolline-N-oxide (DMPO), 3,3,5,5 tetramethyl-1-pyrolline-N-oxide (TMPO) and 1-alpha-phenyl-tert-butyl nitrone (PBN) in the presence of hydrogen peroxide.
    Free radical research, 1994, Volume: 20, Issue:5

    Topics: Cyclic N-Oxides; Drug Stability; Electron Spin Resonance Spectroscopy; Hydrogen Peroxide; Hydroxyl Radical; Kinetics; Myoglobin; Nitrogen Oxides

1994
DNA breaking activity of the carbon-centered radical generated from 2,2'-azobis(2-amidinopropane) hydrochloride (AAPH).
    Free radical research communications, 1993, Volume: 19, Issue:5

    Topics: Amidines; Catalase; Cyclic N-Oxides; DNA; DNA Damage; Electron Spin Resonance Spectroscopy; Electrophoresis, Agar Gel; Free Radicals; Hydroxyl Radical; Nitrogen Oxides; Oxygen; Spin Labels; Superoxide Dismutase

1993
Nitrone spin-traps block calcium channels and induce pulmonary artery relaxation independent of free radicals.
    Biochemical and biophysical research communications, 1993, Jun-30, Volume: 193, Issue:3

    Topics: Animals; Calcium Channels; Catalase; Cells, Cultured; Cyclic N-Oxides; Dose-Response Relationship, Drug; Endothelium, Vascular; Free Radicals; In Vitro Techniques; Male; Meclofenamic Acid; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrogen Oxides; Pulmonary Artery; Pyridines; Rats; Rats, Sprague-Dawley; Spin Labels; Superoxide Dismutase

1993
Biological spin trapping. II. Toxicity of nitrone spin traps: dose-ranging in the rat.
    Journal of biochemical and biophysical methods, 1995, Volume: 30, Issue:4

    Topics: Animals; Cyclic N-Oxides; Dose-Response Relationship, Drug; Male; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Spin Labels

1995
Oxidation of spin-traps by chlorine dioxide (ClO2) radical in aqueous solutions: first ESR evidence of formation of new nitroxide radicals.
    Free radical biology & medicine, 1996, Volume: 20, Issue:6

    Topics: Chlorates; Chlorine; Chlorine Compounds; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Molecular Structure; Nitrogen Oxides; Oxidation-Reduction; Oxides; Spin Labels; Titanium

1996
Detection of hydroxyl and carbon-centred radicals by EPR spectroscopy after ischaemia and reperfusion of the rat kidney.
    Free radical research, 1996, Volume: 25, Issue:1

    Topics: Animals; Carbon; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Hydroxyl Radical; In Vitro Techniques; Ischemia; Kidney; Leukocytes; Male; Nitrogen Oxides; Rats; Rats, Wistar; Reperfusion

1996
Involvement of oxidative stress in 3-nitropropionic acid neurotoxicity.
    Neurochemistry international, 1996, Volume: 29, Issue:2

    Topics: Animals; Benzenesulfonates; Cyclic N-Oxides; Hydroxyl Radical; Male; Nervous System Diseases; Nitro Compounds; Nitrogen Oxides; Oxidative Stress; Propionates; Rats; Rats, Sprague-Dawley; Spin Labels

1996
Blood chemistry changes in the rat induced by high doses of nitronyl free radical spin traps.
    Free radical biology & medicine, 1996, Volume: 21, Issue:4

    Topics: Animals; Blood Glucose; Blood Proteins; Blood Urea Nitrogen; Cyclic N-Oxides; Electrolytes; Enzymes; Free Radicals; Injections, Intraperitoneal; Male; Nitrogen Oxides; Pyridines; Rats; Rats, Sprague-Dawley; Spin Labels

1996
Aryl radical formation during the metabolism of arylhydrazines by microsomes.
    Chemical research in toxicology, 1997, Volume: 10, Issue:12

    Topics: Animals; Cell Line, Transformed; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Keratinocytes; Mice; Microsomes, Liver; Mutagenesis; Nitrogen Oxides; Rats; Spin Labels; Spin Trapping

1997
2-2'-Pyridylisatogen, a selective allosteric modulator of P2 receptors, is a spin trapping agent.
    Biochemical and biophysical research communications, 1998, Jan-14, Volume: 242, Issue:2

    Topics: Allosteric Regulation; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Hydrogen Peroxide; Hydroxyl Radical; Iron; Isatin; Kinetics; Molecular Structure; Nitrogen Oxides; Receptors, Purinergic P2; Spin Labels; Spin Trapping; Superoxides; Xanthine; Xanthine Oxidase

1998
Enhancement of hydroxyl radical generation in the Fenton reaction by alpha-hydroxy acid.
    Biochemistry and molecular biology international, 1998, Volume: 46, Issue:1

    Topics: Catalase; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Ethanol; Glycolates; Hydrogen-Ion Concentration; Hydroxy Acids; Hydroxybutyrates; Hydroxyl Radical; Lactic Acid; Nitrogen Oxides; Spin Labels; Superoxide Dismutase; Superoxides

1998
High-performance liquid chromatography study of the pharmacokinetics of various spin traps for application to in vivo spin trapping.
    Free radical biology & medicine, 1999, Volume: 27, Issue:1-2

    Topics: Animals; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Mice; Mice, Inbred BALB C; Molecular Structure; Nitrogen Oxides; Pyridines; Spin Labels

1999
Commentary: possible mechanisms for strand-breaks in DNA induced by stirring.
    Free radical research, 2001, Volume: 34, Issue:5

    Topics: Biochemistry; Cyclic N-Oxides; DNA; DNA Damage; Free Radicals; Nitrogen Oxides; Nitroso Compounds; Spin Labels

2001
Inactivation of the 2-oxo acid dehydrogenase complexes upon generation of intrinsic radical species.
    European journal of biochemistry, 2002, Volume: 269, Issue:20

    Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Catalysis; Coenzyme A; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Enzyme Activation; Flavin-Adenine Dinucleotide; Free Radicals; Ketone Oxidoreductases; Multienzyme Complexes; NAD; Nitrogen Oxides; Spin Labels; Superoxides; Thioctic Acid; Thioredoxins

2002
In vitro genotoxicity of lead acetate: induction of single and double DNA strand breaks and DNA-protein cross-links.
    Mutation research, 2003, Mar-03, Volume: 535, Issue:2

    Topics: Calcium Chloride; Comet Assay; Cyclic N-Oxides; DNA; DNA Damage; DNA Repair; Endopeptidase K; Humans; In Vitro Techniques; Kinetics; Lymphocytes; Male; Nitrogen Oxides; Organometallic Compounds; Proteins

2003
Electron spin resonance study of phosphorus-nitroxides from 1,3-additions of silicon-phosphorus reagents to nitrones.
    Magnetic resonance in chemistry : MRC, 2004, Volume: 42, Issue:10

    Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Hydroxylamines; Magnetic Resonance Spectroscopy; Molecular Structure; Nitrogen Oxides; Organometallic Compounds; Organosilicon Compounds; Phosphorus; Phosphorus Compounds; Silicon

2004
Study of the oxidative stress in a rat model of chronic brain hypoperfusion.
    Neurochemistry international, 2005, Volume: 46, Issue:8

    Topics: Animals; Ascorbic Acid; Brain; Brain Ischemia; Chronic Disease; Creatine Kinase; Cyclic N-Oxides; Dementia; Disease Models, Animal; Energy Metabolism; Free Radicals; Hydroxyl Radical; Male; Mitochondria; Molecular Conformation; Nitrogen Oxides; Oxidative Phosphorylation; Oxidative Stress; Rats; Rats, Wistar; Spin Trapping

2005
ESR spin trapping of a carbon-centered free radical from agonist-stimulated human platelets.
    Free radical biology & medicine, 2005, Jul-15, Volume: 39, Issue:2

    Topics: Arachidonic Acid; Blood Platelets; Carbon; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Humans; Models, Biological; Nitric Oxide; Nitrogen Oxides; Peroxides; Platelet Aggregation; Prostaglandins; Time Factors

2005
Free radical generation during chemical depolymerization of heparin.
    Analytical biochemistry, 2005, Sep-15, Volume: 344, Issue:2

    Topics: Catalysis; Copper; Cyclic N-Oxides; Disaccharides; Electron Spin Resonance Spectroscopy; Ferrous Compounds; Free Radicals; Heparin; Heparin, Low-Molecular-Weight; Hydrogen-Ion Concentration; Hydroxyl Radical; Nitrogen Oxides; Reproducibility of Results; Spin Labels

2005
High static pressure alters spin trapping rates in solution. Dependence on the structure of nitrone spin traps.
    Organic & biomolecular chemistry, 2006, Mar-07, Volume: 4, Issue:5

    Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Molecular Structure; Nitrogen Oxides; Pressure; Pyridines; Solutions; Spin Labels; Spin Trapping

2006
Assessment of genotoxicity of methyl-tert-butyl ether, benzene, toluene, ethylbenzene, and xylene to human lymphocytes using comet assay.
    Journal of hazardous materials, 2008, May-01, Volume: 153, Issue:1-2

    Topics: Adult; Cells, Cultured; Comet Assay; Cyclic N-Oxides; DNA Breaks, Double-Stranded; DNA Breaks, Single-Stranded; DNA Repair; Environmental Pollutants; Female; Free Radical Scavengers; Humans; Hydrocarbons, Aromatic; Lymphocytes; Methyl Ethers

2008
Mechanistic studies of the reactions of nitrone spin trap PBN with glutathiyl radical.
    The journal of physical chemistry. B, 2008, Apr-17, Volume: 112, Issue:15

    Topics: Antioxidants; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Glutathione; Lasers; Magnetic Resonance Spectroscopy; Magnetics; Molecular Structure; Nitrogen Oxides; Oxidation-Reduction; Photolysis; S-Nitrosoglutathione; Time Factors

2008
Using cyclodextrins to encapsulate oxygen-centered and carbon-centered radical adducts: the case of DMPO, PBN, and MNP spin traps.
    The journal of physical chemistry. A, 2010, Jun-03, Volume: 114, Issue:21

    Topics: Acetic Acid; Butanes; Carbon; Cyclic N-Oxides; Cyclodextrins; Free Radicals; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Conformation; Nitroso Compounds; Oxygen; Spin Trapping

2010
Inhibition of ROS-induced apoptosis in endothelial cells by nitrone spin traps via induction of phase II enzymes and suppression of mitochondria-dependent pro-apoptotic signaling.
    Biochemical pharmacology, 2012, Aug-15, Volume: 84, Issue:4

    Topics: Animals; Aorta; Apoptosis; Caspase 3; Cattle; Cell Nucleus; Cells, Cultured; Cyclic N-Oxides; Cytoprotection; Endothelial Cells; Enzyme Activation; Glutathione Peroxidase; Glutathione Reductase; Heme Oxygenase-1; Hydrogen Peroxide; Mitochondria; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oxidative Stress; Oxidoreductases; Protein Transport; Reactive Oxygen Species; Signal Transduction; Spin Trapping

2012