Compounds > phenyl biguanide

phenyl biguanide and tropisetron

phenyl biguanide has been researched along with tropisetron in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (45.45)18.2507
2000's5 (45.45)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Borrelli, G; Budriesi, R; Butini, S; Caccia, S; Cagnotto, A; Campiani, G; Catalanotti, B; Chiarini, A; Coccone, SS; Colovic, M; Fattorusso, C; Fiorini, I; Fracasso, C; Gemma, S; Hamon, M; Ioan, P; Mennini, T; Morelli, E; Nacci, V; Novellino, E; Persico, M; Ros, S1
Smith, DJ; Smith, DL; Williams, GM1
Higgins, GA; Joharchi, N; Sellers, EM1
Barrett, JE; Critchett, D; Hu, W; Sokol, PT; Solomon, AJ; Toral, J; Ziai, MR1
Jordan, D; Ramage, AG; Wang, Y1
Blandina, P; Ceccarelli, I; Cecchi, M; Giovannini, MG; Goldfarb, J; Molinari, B1
Linz, P; Veelken, R1
Funahashi, M; Matsuo, R; Mitoh, Y1
Katsuumi, I; Matsumoto, S; Oshima, K; Takeda, M; Tanimoto, T1
Ikeda, M; Matsumoto, S; Takeda, M; Tsutsui, Y1
Bartman, ME; Johnson, SM; Wilkerson, JE1

Other Studies

11 other study(ies) available for phenyl biguanide and tropisetron

ArticleYear
Specific targeting of peripheral serotonin 5-HT(3) receptors. Synthesis, biological investigation, and structure-activity relationships.
    Journal of medicinal chemistry, 2009, Jun-11, Volume: 52, Issue:11

    Topics: Animals; Baroreflex; Chemical Phenomena; Female; Guinea Pigs; Heart; Heart Atria; Male; Mice; Models, Molecular; Myocardium; Pyrroles; Quinoxalines; Quipazine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists; Structure-Activity Relationship

2009
5-HT3 receptors are not involved in the modulation of the K(+)-evoked release of [3H]5-HT from spinal cord synaptosomes of rat.
    Neuropharmacology, 1992, Volume: 31, Issue:8

    Topics: Animals; Biguanides; Bufotenin; Hydroxyindoleacetic Acid; In Vitro Techniques; Indoles; Male; Potassium; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spinal Cord; Synaptosomes; Tropisetron

1992
Behavioral effects of the 5-hydroxytryptamine3 receptor agonists 1-phenylbiguanide and m-chlorophenylbiguanide in rats.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:3

    Topics: Animals; Behavior, Animal; Biguanides; Conditioning, Psychological; Dopamine; Haloperidol; Indoles; Injections, Intraventricular; Male; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists; Tropisetron

1993
5-HT3 receptor-independent inhibition of the depolarization-induced 86Rb efflux from human neuroblastoma cells, TE671, by ondansetron.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:7

    Topics: Anti-Anxiety Agents; Benzamides; Benzofurans; Biguanides; Bridged Bicyclo Compounds, Heterocyclic; Humans; Hypoglycemic Agents; Indazoles; Indoles; Neuroblastoma; Neurotoxins; Ondansetron; Potassium Channels; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Rubidium Radioisotopes; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Tropanes; Tropisetron; Tumor Cells, Cultured

1995
Mediation by 5-HT3 receptors of an excitatory effect of 5-HT on dorsal vagal preganglionic neurones in anaesthetized rats: an ionophoretic study.
    British journal of pharmacology, 1996, Volume: 118, Issue:7

    Topics: Anesthesia, General; Animals; Biguanides; Extracellular Space; Granisetron; Indoles; Iontophoresis; Male; Motor Neurons; Nerve Fibers; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tropisetron; Vagus Nerve

1996
Serotonergic modulation of acetylcholine release from cortex of freely moving rats.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:3

    Topics: Acetylcholine; Animals; Biguanides; Cerebral Cortex; Hippocampus; Indoles; Male; Potassium; Rats; Rats, Wistar; Serotonin Antagonists; Serotonin Receptor Agonists; Tetrodotoxin; Tropisetron

1998
Serotonin 5-HT(3) receptors on mechanosensitive neurons with cardiac afferents.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:5

    Topics: Afferent Pathways; Angiotensin II; Animals; Biguanides; Cells, Cultured; Electric Conductivity; Gadolinium; Heart; Hypotonic Solutions; Indoles; Male; Mechanoreceptors; Neurons; Nodose Ganglion; Osmolar Concentration; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists; Stress, Mechanical; Tropisetron

2002
Activation of presynaptic 5-HT3 receptors facilitates glutamatergic synaptic inputs to area postrema neurons in rat brain slices.
    Methods and findings in experimental and clinical pharmacology, 2004, Volume: 26, Issue:8

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Antiemetics; Area Postrema; Biguanides; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Indoles; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Presynaptic; Serotonin; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Serotonin Receptor Agonists; Synaptic Transmission; Tropisetron

2004
Tooth-pulp-evoked rostral spinal trigeminal neuronal excitation is attenuated by the activation of 5-HT3 receptors via GABAergic interneurons in the rat.
    Brain research, 2006, Sep-13, Volume: 1109, Issue:1

    Topics: Action Potentials; Animals; Bicuculline; Biguanides; Dental Pulp; Dose-Response Relationship, Drug; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Indoles; Interneurons; Iontophoresis; Male; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists; Trigeminal Nucleus, Spinal; Tropisetron

2006
Excitability of small-diameter trigeminal ganglion neurons by 5-HT is mediated by enhancement of the tetrodotoxin-resistant sodium current due to the activation of 5-HT(4) receptors and/or by the inhibition of the transient potassium current.
    Neuroscience, 2008, Dec-02, Volume: 157, Issue:3

    Topics: Aniline Compounds; Animals; Animals, Newborn; Antibodies, Heterophile; Biguanides; Biophysics; Cells, Cultured; Dose-Response Relationship, Drug; Electric Stimulation; Indoles; Membrane Potentials; Neurons; Patch-Clamp Techniques; Piperidines; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sodium Channel Blockers; Tetrodotoxin; Trigeminal Ganglion; Tropisetron

2008
5-HT3 receptor-dependent modulation of respiratory burst frequency, regularity, and episodicity in isolated adult turtle brainstems.
    Respiratory physiology & neurobiology, 2010, Jun-30, Volume: 172, Issue:1-2

    Topics: Action Potentials; Afferent Pathways; Animals; Biguanides; Dose-Response Relationship, Drug; Hypoglossal Nerve; In Vitro Techniques; Indoles; Physical Stimulation; Receptors, Serotonin, 5-HT3; Respiration; Respiratory Center; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Serotonin Agents; Time Factors; Tropanes; Tropisetron; Turtles

2010