Page last updated: 2024-08-23

phenyl acetate and ursodeoxycholic acid

phenyl acetate has been researched along with ursodeoxycholic acid in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's3 (60.00)2.80

Authors

AuthorsStudies
Bacon, BR; Bernstein, DE; Boudes, PF; Bowlus, CL; Buggisch, P; Chera, H; Choi, YJ; Clark, V; Corless, L; Doerffel, Y; Freilich, BL; Galambos, MR; Gitlin, N; Gordon, SC; Hartleb, M; Hartmann, H; Hirschfield, GM; Janczewska, E; Jonas, ME; Jones, D; Kremer, AE; Levy, C; Martin, R; McWherter, CA; Mells, GF; Odin, JA; Rochling, F; Shah, H; Sheridan, D; Shiffman, ML; Smith, JH; Steinberg, A; Swain, MG; Varga, M; Vierling, JM; Wörns, MA1
Mothersill, C; Rollo, D; Seymour, C; Vo, NTK; Vukmirovic, D1
Aspinall, RJ; Berg, CP; Boudes, P; Bowlus, CL; Choi, YJ; Dörffel, Y; Galambos, MR; Goel, A; Gordon, SC; Harrison, SA; Hirschfield, GM; Jones, DEJ; Kremer, AE; Levy, C; Mayo, MJ; McWherter, CA; Neff, GW; Sheridan, DA; Shiffman, ML; Stanca, CM; Steinberg, A; Swain, MG; Thuluvath, PJ; Vierling, JM1
Mishra, AK; Singh, SP1
Andreone, P; Aspinall, RJ; Boudes, PF; Bowlus, CL; Choi, YJ; Corpechot, C; Dalekos, GN; Drenth, JPH; Fassio, E; Forman, L; Gonzalez-Huezo, MS; Gordon, SC; Gulamhusein, A; Heneghan, MA; Hinrichsen, H; Hirschfield, GM; Invernizzi, P; Janczewska, E; Jeong, SH; Jones, DEJ; Kowdley, KV; Kremer, AE; Ladrón de Guevara, AL; Lawitz, EJ; Leggett, BA; Levy, C; Mayo, MJ; McWherter, CA; Nevens, F; Pratt, DS; Raikhelson, K; Ryder, SD; Shiffman, ML; Steinberg, A; Swain, MG; Trivedi, PJ; Vargas, V; Vierling, JM; Zigmond, E; Zuckerman, E1

Trials

3 trial(s) available for phenyl acetate and ursodeoxycholic acid

ArticleYear
Seladelpar (MBX-8025), a selective PPAR-δ agonist, in patients with primary biliary cholangitis with an inadequate response to ursodeoxycholic acid: a double-blind, randomised, placebo-controlled, phase 2, proof-of-concept study.
    The lancet. Gastroenterology & hepatology, 2017, Volume: 2, Issue:10

    Topics: Acetates; Adult; Aged; Alanine Transaminase; Cholangitis; Diarrhea; Double-Blind Method; Drug Administration Schedule; Female; Humans; Liver; Male; Middle Aged; Nausea; PPAR delta; Pruritus; Treatment Outcome; Triazoles; Ursodeoxycholic Acid

2017
A phase II, randomized, open-label, 52-week study of seladelpar in patients with primary biliary cholangitis.
    Journal of hepatology, 2022, Volume: 77, Issue:2

    Topics: Acetates; Adult; Alkaline Phosphatase; Disease Progression; Humans; Liver Cirrhosis, Biliary; Pruritus; Ursodeoxycholic Acid

2022
Seladelpar efficacy and safety at 3 months in patients with primary biliary cholangitis: ENHANCE, a phase 3, randomized, placebo-controlled study.
    Hepatology (Baltimore, Md.), 2023, 08-01, Volume: 78, Issue:2

    Topics: Acetates; Alkaline Phosphatase; Cholagogues and Choleretics; Humans; Liver Cirrhosis, Biliary; Pruritus; Ursodeoxycholic Acid

2023

Other Studies

2 other study(ies) available for phenyl acetate and ursodeoxycholic acid

ArticleYear
Characterization of Radioprotective, Radiomitigative and Bystander Signaling Modulating Effects of Endogenous Metabolites - Phenylacetate, Ursodeoxycholate and Tauroursodeoxycholate - on HCT116 Human Colon Carcinoma Cell Line.
    Radiation research, 2019, Volume: 192, Issue:1

    Topics: Acetates; Bystander Effect; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Radiation; HCT116 Cells; Humans; Phenols; Radiation-Protective Agents; Signal Transduction; Taurochenodeoxycholic Acid; Ursodeoxycholic Acid

2019
Seladelpar in patients with primary biliary cholangitis: Need for a closer look!
    Journal of hepatology, 2022, Volume: 77, Issue:5

    Topics: Acetates; Cholagogues and Choleretics; Cholangitis; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2022