phenyl acetate has been researched along with piperidines in 142 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 36 (25.35) | 18.7374 |
| 1990's | 20 (14.08) | 18.2507 |
| 2000's | 42 (29.58) | 29.6817 |
| 2010's | 35 (24.65) | 24.3611 |
| 2020's | 9 (6.34) | 2.80 |
| Authors | Studies |
|---|---|
| Cayen, MN; Dubuc, J; Dvornik, D | 1 |
| Igata, H; Nishida, T; Okabe, S; Takagi, K | 1 |
| Aoki, I; Kamei, C; Tasaka, K; Tsujimoto, S; Yoshida, T | 1 |
| Burstein, M; Michaelson, DM | 1 |
| Coleman, JE; Mushak, P; Taylor, JS | 1 |
| Ali, B; Dwivedi, C; Parmar, SS | 1 |
| McConnell, HM; Morrisett, JD; Wien, RW | 1 |
| Adams, E; Chang, YF | 1 |
| Paleg, L; Sabine, JR | 1 |
| Blumenfeld, LA; Ignatéva, LG | 1 |
| Iida, K; Inai, S; Nagaki, K | 1 |
| Barker, KK; Fox, RM; Lewis, NJ; Mertes, MP | 1 |
| Indenbom, ML; Khromov-Borisov, NV; Rozengart, EV; Soboleva, IN; Tikhonova, LN | 1 |
| Carter, P | 1 |
| Koss, FW; Vollmer, KO | 1 |
| Herrmann, M; Koss, FW; Vollmer, KO | 1 |
| Bloomer, W; Lewis, FS; Rutman, RJ | 1 |
| Böhme, H; Dehmel, H | 2 |
| Casy, AF | 1 |
| Brown, RG; Delgado, JN; Isaacson, EI; Schwartz, HF | 1 |
| Lakshmi, SU; Ramachandran, LK | 1 |
| Keup, U; Schneider, F; Seeber, S | 1 |
| Kulicki, M; Noszczyk, W; Szretter-Szmid, M; Wichrzycka, E | 1 |
| Ho, RS; Kelly, LA; Timms, AR; Trapold, JH | 1 |
| Cudlín, J; Půza, M; Rickards, RW; Vanĕk, Z; Vondrácek, M | 1 |
| Camerman, A; Camerman, N; Cheng, AC; DeGraw, JI; Keys, C; Loew, GH; Spangler, D; Toll, L; Uyeno, ET | 1 |
| Reddy, JK; Simmon, VF; Warren, JR | 1 |
| Braden, B; Caspary, WF; Duan, LP; Lembcke, B | 1 |
| Ikarashi, Y; Misaki, N; Ohba, S; Ohbayashi, S; Uchida, M | 1 |
| Aijima, H; Hamada, K; Nishino, K; Sekiguchi, H; Taga, F; Uchida, H | 1 |
| Pichersky, E | 1 |
| Bandi, JC; Bustos Fernandez, L; Celener, D; De Paula, JA; Gravelle, PC; Ledesma de Paolo, MI; Rosembeck, G | 1 |
| Fan, A; Fang, Z; Wang, J; Wang, Y; Zhang, L | 1 |
| Fukushi, K; Ikota, N; Irie, T; Iyo, M; Nagatsuka, S; Namba, H; Tamagami, H | 1 |
| Kobayashi, F; Ohkubo, H; Ohsawa, A; Sekiguchi, H; Taga, F | 1 |
| Alig, L; Beresini, M; Blackburn, B; Bunting, S; Hadváry, P; Knopp, D; Levet-Trafit, B; Lipari, MT; Modi, NB; Müller, M; Müller, MH; Refino, CJ; Schmitt, M; Schönholzer, P; Steiner, B; Weiss, S; Weller, T | 1 |
| Dervan, PB; Grant, KB | 1 |
| Bormans, G; Kilbourn, MR; Sherman, P; Snyder, SE | 1 |
| Carroll, PT | 1 |
| Fitzgerald, DJ; Murphy, NP; Pratico, D | 1 |
| Besse, P; Combourieu, B; Delort, AM; Poupin, P; Sancelme, M; Truffaut, N; Veschambre, H | 1 |
| Aoki, T; Honda, S; Kurata, Y; Matsuzawa, Y; Seki, J; Shiraga, M; Tomiyama, Y | 1 |
| Fukushi, K; Irie, T; Iyo, M; Nagatsuka, S; Namba, H; Shinotoh, H; Sudo, Y; Suhara, T; Suzuki, K | 1 |
| Boyce, S; Hill, RG; Mason, G; O'Donnell, R; Rigby, M; Rupniak, NM; Sirinathsinghji, D; Webb, JK; Wyatt, A | 1 |
| Buffa, C; Dallocchio, C; Mazzarello, P | 1 |
| Falkiewicz, B | 1 |
| Jang, IK; Sabatine, MS | 1 |
| Bachmann, LM; Golder, S; Kleijnen, J; McDonagh, MS; ter Riet, G | 1 |
| Barabás, P; Egyed, O; Kardos, J; Kökösi, J; Kovács, I; Nagy, PI; Nyikos, L; Skuban, N; Szárics , E; Takács-Novák, K; Temesváriné-Major, E | 1 |
| Aotsuka, A; Fukushi, K; Irie, T; Iyo, M; Nagatsuka , S; Namba, H; Ota, T; Shinotoh, H; Tanada, S; Tanaka, N | 1 |
| Bauer, B; Heiss, WD; Herholz, K; Lenz, O; Lercher, M; Wienhard, K | 1 |
| Hughes, J; Maneuf, YP; McKnight, AT | 1 |
| Bauer, B; Heiss, WD; Herholz, K; Kracht, L; Lenz, MO; Mielke, R; Strotmann, T; Wienhard, K | 1 |
| Evans, CS; Goodall, DM; Keely, BJ; Startin, JR | 1 |
| Aotsuka, A; Fukushi, K; Irie, T; Iyo, M; Nagatsuka Si, S; Namba, H; Ota, T; Shinotoh, H; Tanada, S; Tanaka, N | 1 |
| Ikeura, Y; Inatomi, N; Okano, S | 1 |
| Carroll, PT; Roghani, A | 1 |
| Furutsuka, K; Haradahira, T; Irie, T; Kida, T; Noguchi, J; Suzuki, K; Tsuchiyama, A; Yoshida, Y; Zhang, MR | 1 |
| Field, MJ; Gonzalez, MI; Singh, L; Tallarida, RJ | 1 |
| Assié, MB; Bardin, L; Carilla-Durand, E; Colpaert, FC; Cosi, C; Koek, W; Pauwels, PJ; Tarayre, JP; Vacher, B; Wiesenfeld-Hallin, Z; Xu, XJ | 1 |
| Järvenpää, T; Kaasinen, V; Kurki, T; Någren, K; Oikonen, V; Rinne, JO; Roivainen, A; Yu, M | 1 |
| Furutsuka, K; Irie, T; Kida, T; Kikuchi, T; Maeda, J; Okauchi, T; Suzuki, K; Zhang, MR | 1 |
| Freeman, MP; Gelenberg, AJ; Gnanadesikan, M | 1 |
| Blanco, C; Blanco-Jerez, CR; Liebowitz, MR; Marshall, RD; Sánchez-Lacay, A; Schmidt, A; Schneier, FR | 1 |
| KLOSA, J | 2 |
| GROSS, F; MEIER, R; TRIPOD, J | 1 |
| BELLUCCI, G | 1 |
| KARIYONE, K | 1 |
| DVORAK, G; ROTH, HJ | 1 |
| DVORAK, G; ROTH, HJ; SCHWENKE, C | 1 |
| CUGURRA, F; PAPADIA, S; PONTREMOLI, M; VACCARI, A | 1 |
| BARBARA, A; CUGURRA, F; PAPADIA, S | 1 |
| RIESE, JA | 1 |
| Bauer, B; Heiss, WD; Herholz, K; Kalbe, E; Lenz, O; Schröder, H; Weisenbach, S; Zündorf, G | 1 |
| Felouzis, E; Gustorff, B; Hoechtl, K; Kress, HG; Lehr, S; Sycha, T | 1 |
| Carella, A; Carver, G; Chapman, KT; Danzeisen, R; DeMartino, JA; Emini, EA; Gould, SL; Hale, JJ; Hazuda, D; Holmes, K; Kessler, J; Kwei, GY; Lineberger, J; Lynch, CL; Lyons, K; Malkowitz, L; Miller, MD; Mills, SG; Pivnichny, JV; Schleif, WA; Shah, S; Shen, DM; Shu, M; Siciliano, SJ; Springer, MS; Willoughby, CA | 1 |
| Hirai, Y; Kinoshita, Y; Mori, S; Yamauchi, S | 1 |
| Carella, A; Carver, G; Donnelly, KL; Emini, EA; Gould, SL; Guthikonda, RN; Hazuda, D; Holmes, K; Kessler, J; Lineberger, J; MacCoss, M; Malkowitz, L; Miller, MD; Mills, SG; Schleif, WA; Shah, SK; Shankaran, K; Siciliano, SJ; Springer, MS | 1 |
| Fujita, M; Fujiwara, K; Hirayama, S; Kim, WH; Ohki, Y; Okuyama, T; Sakanishi, Y; Tatsumi, K; Yoshioka, Y | 1 |
| Aotsuka, A; Arai, H; Fukushi, K; Irie, T; Iyo, M; Nagatsuka, S; Namba, H; Ota, T; Sato, K; Shinotoh, H; Shiraishi, T; Tanada, S; Tanaka, N | 1 |
| Häkkinen, ST; Laakso, I; Maaheimo, H; Oksman-Caldentey, KM; Rischer, H; Seppänen-Laakso, T | 1 |
| Arano, Y; Fukushi, K; Ikota, N; Irie, T; Kikuchi, T; Okamura, T; Suzuki, K; Zhang, MR | 1 |
| Couture, R; Deschamps, K | 1 |
| Bradshaw, EL; Gustafson, DL; Long, ME; Zirrolli, JA | 1 |
| Karaki, S; Kuwahara, A; Mitsui, R; Ono, S | 1 |
| Bosso, N; Carpinelli, A; Cattaneo, A; Fazio, F; Galli Kienle, M; Magni, F; Matarrese, M; Todde, S; Turolla, E | 1 |
| Burghaus, L; Heiss, WD; Herholz, K; Hilker, R; Jacobs, AH; Kalbe, E; Klein, JC; Thomas, AV; Weisenbach, S | 1 |
| Baldwin, JJ; Chiba, J; Hussain, Z; Machinaga, N; McDonald, E; Moriarty, KJ; Nakayama, A; Saionz, KW; Sarko, CR; Swanson, R; Takashi, T; Takayama, G; Wong, A; Yokoyama, M | 1 |
| Brouillette, J; Cloutier, F; Couture, R; Deschamps, K; Neugebauer, W; Ongali, B | 1 |
| Backman, JT; Kajosaari, LI; Neuvonen, PJ; Niemi, M | 1 |
| Arora, H; Brady, ED; Brechbiel, MW; Chong, HS; Garmestani, K; Milenic, DE; Pfiester, C | 1 |
| Bueno, L; Furness, JB; Sanger, GJ; Tuladhar, BR | 1 |
| Bäckvall, JE; Bogár, K; Fransson, AB; Olofsson, B | 1 |
| Hampton, T | 1 |
| Bachar, SC; Das, B; Kundu, J; Kundu, JK; Uddin, MA | 1 |
| Hizue, M; Imai, A; Toide, K | 1 |
| Fukushi, K; Irie, T; Kikuchi, T; Okamura, T; Zhang, MR | 1 |
| Andrade, P; Angagaw, M; Bi, G; Black, RM; Crispino, J; Cruz, JC; Fan, E; Farris, G; Hamblett, C; Hubbs, J; Hughes, BL; Kenific, CM; Middleton, RE; Munoz, B; Nikov, G; Sajonz, P; Shah, S; Shearman, M; Shomer, N; Sloman, D; Stanton, MG; Szewczak, AA; Tanga, F; Tudge, MT | 1 |
| Elliott, RL; Giblin, GM; Hall, A; Hussain, I; Musgrave, J; Naylor, A; Sasse, R; Smith, B | 1 |
| Ahmed, S; Brackenborough, K; Chapman, T; Facci, L; Giblin, GM; Gonzalez, MI; Hall, A; Harrison, DC; Hawkins, J; Hussain, I; Marshall, I; Mead, TL; Richardson, JC; Skaper, SD; Smith, BB | 1 |
| Honda, S; Kawaura, K; Miki, R; Shehata, AM; Shirasaki, T; Soeda, F; Takahama, K; Urashima, Y | 1 |
| Fukumura, T; Fukushi, K; Irie, T; Kikuchi, T; Nagai, Y; Ohya, T; Okamura, T; Suhara, T; Zhang, MR | 1 |
| Futatsubashi, M; Irie, T; Iwata, Y; Kikuchi, M; Matsumoto, K; Mori, N; Nakamura, K; Ouchi, Y; Suda, S; Sugihara, G; Sugiyama, T; Suzuki, K; Takebayashi, K; Takei, N; Tsuchiya, KJ; Tsujii, M; Wakuda, T; Yoshihara, Y | 1 |
| Ahmed, S; Chapman, T; Davis, RP; Giblin, GM; Gonzalez, MI; Hall, A; Harrison, DC; Hawkins, J; Hussain, I; Marshall, I; Mead, TL; Medhurst, A; Richardson, J; Smith, B | 1 |
| Arponen, E; Luoto, P; Någren, K; Oikonen, V; Östberg, A; Rinne, JO; Tenovuo, O; Virta, J | 1 |
| Foti, RS; Rock, DA; VandenBrink, BM; Wahlstrom, JL; Wienkers, LC | 1 |
| Choi, SY; Chung, JK; Chung, YK; Hoigebazar, L; Jeong, JM; Lee, DS; Lee, JY; Lee, MC; Lee, YS; Shetty, D | 1 |
| D'hooghe, M; De Kimpe, N; Törnroos, KW; Vervisch, K | 1 |
| Bertoldo, A; Borroni, B; Cappa, SF; Carpinelli, A; Florea, I; Garibotto, V; Herholz, K; Marcone, A; Moresco, RM; Padovani, A; Panzacchi, A; Perani, D; Rinne, JO; Tettamanti, M; Virta, JR | 1 |
| Fukumura, T; Fukushi, K; Irie, T; Kikuchi, T; Ohya, T; Zhang, MR | 1 |
| Bahekar, R; Jadav, P; Jain, M; Joharapurkar, A; Patel, D; Sairam, KV; Shah, K; Shah, SR; Shaikh, M | 1 |
| Akashiba, H; Matsuoka, N; Mitani, Y; Ni, K; Shitaka, Y; Yarimizu, J | 1 |
| Fukumura, T; Irie, T; Kikuchi, T; Ohya, T; Zhang, MR | 1 |
| Cappa, SF; Florea, I; Garibotto, V; Marcone, A; Moresco, R; Panzacchi, A; Perani, D; Rinne, J; Tettamanti, M; Virta, JR | 1 |
| Li, Y; Liu, J; Wang, C; Xue, Z; Yao, J; Ye, W | 1 |
| Allendorf, I; Dietlein, M; Fink, GR; Kracht, L; Kukolja, J; Neumaier, B; Onur, OA; Richter, N; Tittgemeyer, M | 1 |
| Choo, YM; De La Rosa, A; Leal, WS; Xu, P | 1 |
| Andrés, M; Buil, MA; Calbet, M; Casado, O; Castro, J; Eastwood, PR; Eichhorn, P; Ferrer, M; Forns, P; Moreno, I; Petit, S; Roberts, RS | 1 |
| Aswar, M; Aswar, U; Chepurwar, S; Shintre, S | 1 |
| Franke, J; Krische, MJ; Ngo, CQ; Wang, G | 1 |
| Bruchas, MR; Carroll, FI; Chang, SD; Gurevich, VV; Mascarella, SW; Navarro, HA; Spangler, SM | 1 |
| Cho, MH; Jang, Y; Jeong, SH; Kim, JE; Kim, JS; Paik, MK | 1 |
| Dietlein, M; Fink, GR; Kracht, L; Kukolja, J; Michel, A; Neumaier, B; Onur, OA; Richter, N; Tittgemeyer, M | 1 |
| Goda, H; Ito, K; Komatsu, S; Kudo, T; Tanaka, R; Yokosuka, Y | 1 |
| Ahlijanian, MK; Albright, CF; Banks, M; Drexler, DM; Iben, LG; Meredith, JE; Olson, RE; Robertson, AS; Thompson, LA; Toyn, JH; Vite, GD; Wei, C | 1 |
| Morissette, MF; Tso, J; Wigman, L | 1 |
| Beckers, N; Dietlein, M; Fink, GR; Kracht, L; Kukolja, J; Neumaier, B; Onur, OA; Richter, N; Tittgemeyer, M | 1 |
| Kong, L; Li, L; Tian, YP; Xin, CQ; Yang, JX; Yang, L; Zhang, HH; Zhang, MZ; Zhou, HP; Zhu, SJ | 1 |
| Fukushi, K; Higuchi, M; Hirano, S; Irie, T; Kuwabara, S; Ota, T; Sato, K; Shimada, H; Shinotoh, H; Suhara, T; Tanaka, N; Zhang, MR | 1 |
| Fleet, GWJ; Hollinshead, J; Jenkinson, SF; Kato, A; Martínez, RF; Nakagawa, S; Nash, RJ; Wormald, MR | 1 |
| Lavorini, F; Matucci, A; Pistolesi, M; Rossi, O | 1 |
| Dietlein, M; Dillen, K; Dronse, J; Fink, GR; Jacobs, HIL; Kracht, L; Kukolja, J; Langen, KJ; Nellessen, N; Neumaier, B; Onur, OA; Richter, N | 1 |
| Egorov, MP; Elinson, MN; Goloveshkin, AS; Hansford, KA; Karpenko, KA; Minaeva, AP; Vereshchagin, AN | 1 |
| Aoyagi, H; Hirasawa, N; Kajiwara, D; Miyoshi, K; Tanaka, K; Tsunekuni, K | 1 |
| Allocca, M; Correale, C; Danese, S; Fiorino, G; Furfaro, F; Gabbiadini, R; Gilardi, D; Peyrin-Biroulet, L; Zilli, A | 1 |
| Hanada, R | 1 |
| Mahajan, AN; Patel, A; Patel, D; Surti, N; Surti, Z | 1 |
| Mishra, A; Prajapati, P; Surati, P; Tamboli, J | 1 |
| Mishra, A; Prajapati, P; Tamboli, J | 1 |
6 review(s) available for phenyl acetate and piperidines
| Article | Year |
|---|---|
The use of glycoprotein IIb/IIIa inhibitors in patients with coronary artery disease.
Topics: Abciximab; Acetates; Acute Disease; Administration, Oral; Alanine; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Benzamidines; Coronary Disease; Eptifibatide; Hemorrhage; Humans; Immunoglobulin Fab Fragments; Myocardial Infarction; Oximes; Peptides; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Randomized Controlled Trials as Topic; Stents; Syndrome; Thrombocytopenia; Thrombolytic Therapy; Tirofiban; Tyrosine | 2000 |
A rapid and systematic review of the clinical effectiveness and cost-effectiveness of glycoprotein IIb/IIIa antagonists in the medical management of unstable angina.
Topics: Acetates; Angina, Unstable; Biphenyl Compounds; Cost-Benefit Analysis; Eptifibatide; Female; Humans; Male; Oximes; Peptides; Piperidines; Platelet Aggregation Inhibitors; Pyrrolidines; Tirofiban; Tyrosine | 2000 |
Alternatives to lithium and divalproex in the maintenance treatment of bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Calcium Channel Blockers; Carbamazepine; Clozapine; Cyclohexanecarboxylic Acids; Dibenzothiazepines; Donepezil; Fatty Acids, Omega-3; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Indans; Lamotrigine; Lithium Carbonate; Olanzapine; Piperazines; Piperidines; Pirenzepine; Quetiapine Fumarate; Risperidone; Thiazoles; Topiramate; Treatment Outcome; Triazines; Valproic Acid | 2003 |
Pharmacological treatment of social anxiety disorder: a meta-analysis.
Topics: Acetates; Amines; Anti-Anxiety Agents; Antidepressive Agents; Antimanic Agents; Anxiety Disorders; Calcium Channel Blockers; Clonazepam; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Monoamine Oxidase Inhibitors; Phenelzine; Phobic Disorders; Piperidines; Selective Serotonin Reuptake Inhibitors; Treatment Outcome | 2003 |
Defensive and pathological functions of the gastrointestinal NK3 receptor.
Topics: Abdominal Pain; Acetates; Animals; Gastrointestinal Tract; Humans; Piperidines; Quinolines; Receptors, Neurokinin-3; Tachykinins | 2006 |
PK, PD, and interactions: the new scenario with JAK inhibitors and S1P receptor modulators, two classes of small molecule drugs, in IBD.
Topics: Acetates; Animals; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Heterocyclic Compounds, 3-Ring; Humans; Indans; Indoles; Janus Kinase Inhibitors; Oxadiazoles; Piperidines; Pyridines; Pyrimidines; Quinolones; Sphingosine-1-Phosphate Receptors; Triazoles | 2020 |
8 trial(s) available for phenyl acetate and piperidines
| Article | Year |
|---|---|
Positron emission tomographic measurement of brain acetylcholinesterase activity using N-[(11)C]methylpiperidin-4-yl acetate without arterial blood sampling: methodology of shape analysis and its diagnostic power for Alzheimer's disease.
Topics: Acetates; Acetylcholinesterase; Aged; Alzheimer Disease; Arteries; Blood Specimen Collection; Brain; Carbon Radioisotopes; Humans; Middle Aged; Monte Carlo Method; Piperidines; Tomography, Emission-Computed | 2001 |
Kinetic analysis of [(11)C]MP4A using a high-radioactivity brain region that represents an integrated input function for measurement of cerebral acetylcholinesterase activity without arterial blood sampling.
Topics: Acetates; Acetylcholinesterase; Adult; Aged; Alzheimer Disease; Blood Specimen Collection; Brain; Carbon Radioisotopes; Computer Simulation; Humans; Kinetics; Least-Squares Analysis; Middle Aged; Models, Biological; Piperidines; Tomography, Emission-Computed | 2001 |
Brain acetylcholinesterase activity in mild cognitive impairment and early Alzheimer's disease.
Topics: Acetates; Acetylcholinesterase; Aged; Alzheimer Disease; Analysis of Variance; Brain; Carbon Radioisotopes; Cognition Disorders; Female; Hippocampus; Humans; Imaging, Three-Dimensional; Male; Middle Aged; Neuropsychological Tests; Piperidines; Predictive Value of Tests; Reference Values; Tomography, Emission-Computed | 2003 |
The effects of remifentanil and gabapentin on hyperalgesia in a new extended inflammatory skin pain model in healthy volunteers.
Topics: Acetates; Adult; Amines; Analgesics, Opioid; Cross-Over Studies; Cyclohexanecarboxylic Acids; Diazepam; Double-Blind Method; Drug Synergism; Excitatory Amino Acid Antagonists; Female; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Inflammation; Male; Pain Measurement; Pain Threshold; Physical Stimulation; Piperidines; Reaction Time; Remifentanil; Skin; Sunburn; Treatment Outcome | 2004 |
A simple method for the detection of abnormal brain regions in Alzheimer's disease patients using [11C]MP4A: comparison with [123I]IMP SPECT.
Topics: Acetates; Acetylcholinesterase; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Carbon Radioisotopes; Cerebral Cortex; Female; Humans; Image Interpretation, Computer-Assisted; Iofetamine; Male; Middle Aged; Piperidines; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2004 |
Dementia in Parkinson disease: functional imaging of cholinergic and dopaminergic pathways.
Topics: Acetates; Acetylcholine; Acetylcholinesterase; Aged; Atrophy; Binding, Competitive; Brain; Brain Mapping; Dihydroxyphenylalanine; Dopamine; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neural Pathways; Neuropsychological Tests; Parkinson Disease; Piperidines; Positron-Emission Tomography; Synaptic Transmission | 2005 |
Telithromycin, but not montelukast, increases the plasma concentrations and effects of the cytochrome P450 3A4 and 2C8 substrate repaglinide.
Topics: Acetates; Adolescent; Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Biotransformation; Blood Glucose; Carbamates; Cross-Over Studies; Cyclopropanes; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Humans; Hypoglycemic Agents; Ketolides; Leukotriene Antagonists; Male; Piperidines; Quinolines; Sulfides | 2006 |
Safety and Pharmacokinetics of High-Dose TAS-303 in Healthy Japanese Volunteers: A Single-Center, Single-Blind, Randomized, Placebo-Controlled, Parallel-Group, Multiple-Ascending-Dose Study.
Topics: Acetates; Administration, Oral; Adrenergic Uptake Inhibitors; Adult; Area Under Curve; Asian People; Case-Control Studies; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Drug Tolerance; Healthy Volunteers; Humans; Male; Piperidines; Placebos; Safety; Single-Blind Method; Urinary Incontinence, Stress | 2020 |
128 other study(ies) available for phenyl acetate and piperidines
| Article | Year |
|---|---|
Effect of tibric acid on hepatic cholesterol synthesis in rats.
Topics: Acetates; Animals; Cholesterol; Hypolipidemic Agents; Liver; Male; Mevalonic Acid; Phospholipids; Piperidines; Rats; Triglycerides | 1977 |
[Effects of IT-066, a new histamine H2-receptor antagonist, on gastric acid secretion and experimental gastric ulcers in rats and dogs].
Topics: Acetates; Animals; Anti-Ulcer Agents; Carbachol; Depression, Chemical; Dogs; Famotidine; Female; Gastric Acid; Histamine Antagonists; Histamine H2 Antagonists; Male; Pentagastrin; Piperidines; Pyridines; Rats; Rats, Inbred Strains; Stomach Ulcer | 1990 |
Central effect of the potent long-acting H1-antihistamine levocabastine.
Topics: Acetates; Animals; Avoidance Learning; Central Nervous System; Electroencephalography; Histamine H1 Antagonists; Male; Mice; Mice, Inbred Strains; Motor Activity; Oxotremorine; Pain; Piperidines; Rats; Rats, Inbred Strains; Salivation; Sleep; Thiopental; Tremor | 1990 |
Biochemical evidence that acetylcholine release from cholinergic nerve terminals is mostly vesicular.
Topics: Acetates; Acetylcholine; Animals; Electric Organ; In Vitro Techniques; Phencyclidine; Piperidines; Synaptic Vesicles; Synaptosomes; Torpedo | 1985 |
Proton hyperfine splitting in the ESR spectra of a stable hydroxynitroxide and its esters. Application to an ESR assay procedure for alkaline phosphatase.
Topics: Acetates; Alcohols; Alkaline Phosphatase; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Escherichia coli; Esters; Hydrogen-Ion Concentration; Methods; Phosphoric Acids; Piperidines; Protons | 1971 |
Substituted carbamides: interrelationship between anticonvulsant activity and inhibition of nicotinamide adenine dinucleotide-dependent pyruvic acid oxidation.
Topics: Acetates; Amides; Animals; Anticonvulsants; Brain; Carbamates; Chlorine; Enzyme Repression; Mice; Morphine; NAD; Oxidation-Reduction; Oxygen Consumption; Piperidines; Pyrrolidinones; Pyruvate Oxidase; Pyruvates; Rats; Structure-Activity Relationship | 1972 |
Spin-label-induced nuclear relaxation. Distances between bound saccharides, histidine-15, and tryptophan-123 on lysozyme in solution.
Topics: Acetamides; Acetates; Binding Sites; Chemical Phenomena; Chemistry; Cyclic N-Oxides; Deuterium; Electron Spin Resonance Spectroscopy; Glucosamine; Histidine; Magnetic Resonance Spectroscopy; Mathematics; Models, Chemical; Models, Structural; Muramidase; Oligosaccharides; Piperidines; Protein Conformation; Tryptophan | 1972 |
D-lysine catabolic pathway in Pseudomonas putida: interrelations with L-lysine catabolism.
Topics: Acetates; Adipates; Aldehydes; Alkanesulfonates; Amino Acid Isomerases; Carbon Radioisotopes; Carboxylic Acids; Cell-Free System; Chromatography, Ion Exchange; Enzyme Induction; Glutamates; Glutarates; Lysine; Mutagens; Mutation; Nitrosoguanidines; Oxidoreductases, N-Demethylating; Pipecolic Acids; Piperidines; Pseudomonas; Stereoisomerism; Valerates | 1974 |
Inhibition by plant growth retardants of cholesterol biosynthesis in slices of rat liver and hepatoma.
Topics: Acetates; Animals; Anticholesteremic Agents; Carcinoma, Hepatocellular; Cholesterol; Fatty Acids; Liver; Liver Neoplasms; Male; Mevalonic Acid; Neoplasm Transplantation; Neoplasms, Experimental; Onium Compounds; Organophosphorus Compounds; Piperidines; Plant Growth Regulators; Quaternary Ammonium Compounds; Rats | 1971 |
Conformational changes in myosin under ATP hydrolysis.
Topics: Acetates; Adenosine Diphosphate; Adenosine Triphosphate; Binding Sites; Electron Spin Resonance Spectroscopy; Hydrolysis; Kinetics; Myosins; Piperidines; Protein Conformation; Spin Labels; Sulfhydryl Compounds | 1974 |
A new method for the preparation of EAC14 cell with human or guinea-pig serum.
Topics: Acetates; Animals; Calcium; Complement System Proteins; Erythrocytes; Guinea Pigs; Hemolysis; Humans; Immunologic Techniques; Magnesium; Piperidines; Quaternary Ammonium Compounds; Sheep; Temperature | 1974 |
Diacetoxypiperidinium analogs of acetylcholine.
Topics: Acetates; Acetylcholine; Animals; Cholinesterase Inhibitors; Cholinesterases; Eels; Guinea Pigs; Horses; Ileum; In Vitro Techniques; Magnetic Resonance Spectroscopy; Molecular Conformation; Muscle Contraction; Piperidines; Pyridinium Compounds; Stereoisomerism; Structure-Activity Relationship | 1973 |
[New specific substrate for acetylcholinesterase].
Topics: Acetates; Acetylcholinesterase; Animals; Cattle; Cholinesterases; Erythrocytes; Horses; Piperidines; Pyrrolidines | 1973 |
Submicrogram serum copper quantification by spectrophotometry with bis(1-piperidylthiocarbonyl) disulfide.
Topics: Acetates; Bilirubin; Centrifugation; Ceruloplasmin; Copper; Disulfides; Drug Stability; Evaluation Studies as Topic; Humans; Methanol; Methods; Microchemistry; Piperidines; Spectrophotometry; Sulfides; Ultraviolet Rays | 1972 |
[The pharmacokinetics and metabolism of a new choleretic, 3-ethyl-4-oxo-5-piperidino- 2, -thiazolidineacetic acid ethyl ester (Piprozolin) after enteral administration in the rat].
Topics: Acetates; Administration, Oral; Animals; Bile; Carbon Isotopes; Cholagogues and Choleretics; Digestive System; Ethylamines; Feces; Ketones; Kinetics; Male; Piperidines; Rats; Thiazoles | 1972 |
[Research with experimental animals on the mechanism of action of the new choleretic, 3-ethyl-4-oxo-5-piperidino-delta 2, alpha-thiazolidine-acetic acid ethyl ester (Piprozolin)].
Topics: 1-Propanol; Acetates; Animals; Bile; Carbon Isotopes; Catheterization; Cats; Cholagogues and Choleretics; Dogs; Ethylamines; Ketones; Male; Piperidines; Rabbits; Rats; Rats, Inbred Strains; Thiazoles | 1972 |
Metabolic investigations during the development of obesity in bipiperidyl mustard-treated mice.
Topics: Acetates; Adipose Tissue; Animals; Carbon Isotopes; Glucose; Hydroxybutyrates; Mice; Mustard Compounds; Obesity; Piperidines; Starvation | 1967 |
[Chlorination of N-acetyl-piperidine. 15. N-alpha halogen alkyl-carbonic acid amide].
Topics: Acetates; Aluminum; Chemical Phenomena; Chemistry; Chlorine; Chromates; Deuterium; Lithium; Oxidation-Reduction; Piperidines; Spectrum Analysis | 1971 |
[N-alpha-halogen alkyl-carbonic acid amide. 16. Reaction of 2,3,3-trichloro-1-acetyl-piperidine with nucleophilic partners].
Topics: Acetates; Chemical Phenomena; Chemistry; Chlorine; Piperidines | 1971 |
Probable conformations of some reversed esters of meperidine as solutes in water. Conformational factors in 4-phenylpiperidine analgetics.
Topics: Acetates; Alcohols; Animals; Butyrates; Chemical Phenomena; Chemistry; Magnetic Resonance Spectroscopy; Meperidine; Mice; Piperidines; Propionates; Protons; Solubility; Water | 1968 |
Structure-activity relationships among some selected substituted cyanoacetamides.
Topics: Acetates; Amides; Animals; Anticonvulsants; Cyanates; Electroshock; Female; Injections, Intraperitoneal; Morpholines; Piperidines; Pyrrolidines; Rats | 1968 |
A colorimetric micro method for the determination of formyl groups.
Topics: Acetates; Acetone; Amino Acids; Chromatography; Chromatography, Paper; Colorimetry; Formates; Methods; Muramidase; Phenylhydrazines; Piperidines; Tyrothricin | 1969 |
[Cytostatically active N-acyloxymethyl compounds].
Topics: Acetates; Animals; Antineoplastic Agents; Benzoates; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cinnamates; Depression, Chemical; DNA, Neoplasm; Esters; Imidazoles; Imides; In Vitro Techniques; Leucine; Mice; Morpholines; Neoplasm Proteins; Oxazoles; Piperidines; Pyrrolidinones; RNA, Neoplasm; Thymidine; Uridine | 1969 |
[Experimental wound closure by means of our cellular glue].
Topics: Acetates; Animals; Female; Formaldehyde; Granulation Tissue; Male; Methods; Mice; Piperidines; Tissue Adhesives; Wound Healing | 1969 |
Laboratory studies of 1-methyl-4-piperidyl bis(p-chlorophenoxy) acetate (SaH 42-348)--a new hypolipidemic agent.
Topics: Acetates; Animals; Anticholesteremic Agents; Body Weight; Butyrates; Carbon Isotopes; Cholesterol; Hyperlipidemias; Hypolipidemic Agents; Lipids; Liver; Male; Organ Size; Phospholipids; Piperidines; Propylthiouracil; Rats; Triglycerides | 1969 |
Metabolites of Streptomyces noursei. 8. Biogenesis of cycloheximide from the point of view of the glutarimide ring symetry.
Topics: Acetates; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Cycloheximide; Malonates; Methionine; Piperidines; Streptomyces | 1967 |
Analgesics. 3. Synthesis, resolution, X-ray structure determination, receptor binding, and analgesic properties of 3-methyl-3-m-hydroxyphenylpiperidines with N-substituent variation.
Topics: Acetates; Acetic Acid; Analgesics; Animals; Isomerism; Magnetic Resonance Spectroscopy; Models, Chemical; Piperidines; Receptors, Opioid; Receptors, Opioid, mu; Software; Structure-Activity Relationship; X-Ray Diffraction | 1984 |
Properties of hypolipidemic peroxisome proliferators in the lymphocyte [3H]thymidine and Salmonella mutagenesis assays.
Topics: Acetates; Animals; Clofibrate; Concanavalin A; DNA Replication; Glycolates; Hypolipidemic Agents; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Mice; Mice, Inbred C57BL; Microbodies; Microsomes, Liver; Mutagens; Nafenopin; Organoids; Piperidines; Pyrimidines; Rats; Salmonella typhimurium; Thioacetamide; Thymidine | 1980 |
Influence of cisapride on gastric emptying of solids and liquids monitored by 13C breath tests.
Topics: Acetates; Adult; Anti-Ulcer Agents; Breath Tests; Caprylates; Carbon Isotopes; Cisapride; Dyspepsia; Female; Gastric Emptying; Humans; Least-Squares Analysis; Male; Middle Aged; Piperidines; Reference Values; Statistics, Nonparametric | 1995 |
[Therapeutic effect of IGN-2098, a new antiulcer drug (H2-antagonist), in the ulcer diminishing period against acetic acid-induced gastric ulcer in rats].
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Famotidine; Histamine H2 Antagonists; Male; Piperidines; Pyrimidinones; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 1995 |
Healing-promoting action of the new histamine H2-receptor antagonist N-ethyl-N'-[3-[3-(piperidinomethyl)phenoxy]propyl]urea with dual action on chronic gastric and duodenal ulcers induced by acetic acid in rats.
Topics: Acetates; Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Duodenal Ulcer; Famotidine; Gastric Mucosa; Histamine H2 Antagonists; Intestinal Mucosa; Male; Phenylurea Compounds; Piperidines; Rats; Rats, Wistar; Stomach Ulcer | 1993 |
DNA sequencing by the chemical method.
Topics: Acetates; Acetic Acid; Cacodylic Acid; Chemical Precipitation; Electrophoresis, Polyacrylamide Gel; Hydrazines; Piperidines; Sequence Analysis, DNA; Sulfuric Acid Esters | 1993 |
Action of cisapride on rat colonic secretion.
Topics: Acetates; Acetic Acid; Animals; Body Water; Cisapride; Colon; Electrolytes; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Male; Piperidines; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists | 1993 |
[The pharmacodynamics of troxipide on experimental gastric ulcers in rats].
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidine; Female; Male; Piperidines; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Stress, Physiological | 1993 |
Brain acetylcholinesterase activity: validation of a PET tracer in a rat model of Alzheimer's disease.
Topics: Acetates; Acetylcholinesterase; Alzheimer Disease; Amphetamines; Animals; Brain; Carbon Radioisotopes; Iodine Radioisotopes; Iofetamine; Male; Piperidines; Propionates; Rats; Rats, Wistar; Sensitivity and Specificity; Tomography, Emission-Computed | 1996 |
[Influence of KU-1257 on the recurrence and relapse of acetic acid-induced chronic gastric ulcers in rats].
Topics: Acetates; Acetic Acid; Animals; Chronic Disease; Cimetidine; Histamine H2 Antagonists; Male; Phenylurea Compounds; Piperidines; Rats; Rats, Wistar; Recurrence; Stomach Ulcer; Time Factors | 1996 |
Orally active fibrinogen receptor antagonists. 2. Amidoximes as prodrugs of amidines.
Topics: Acetates; Administration, Oral; Amidines; Animals; Anticoagulants; Dogs; Macaca mulatta; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Molecular Structure; Oximes; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prodrugs; Rats; Tyrosine | 1996 |
Sequence-specific alkylation and cleavage of DNA mediated by purine motif triple helix formation.
Topics: Acetates; Alkylation; Binding Sites; DNA; DNA Restriction Enzymes; Electrophoresis, Polyacrylamide Gel; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Piperidines; Plasmids; Purines; Pyrimidines | 1996 |
Synthesis of carbon-11- and fluorine-18-labeled 1-methyl-4-piperidyl-4'-fluorobenzoate and their biodistribution in mice.
Topics: Acetates; Animals; Benzoates; Carbon Radioisotopes; Female; Fluorine Radioisotopes; Isotope Labeling; Mice; Mice, Inbred Strains; Piperidines; Tissue Distribution | 1996 |
Evidence to suggest that extracellular acetate is accumulated by rat hippocampal cholinergic nerve terminals for acetylcholine formation and release.
Topics: Acetate-CoA Ligase; Acetates; Acetylcholine; Animals; Biological Transport; Cholinesterase Inhibitors; Hippocampus; Male; Membrane Potentials; Nerve Endings; Paraoxon; Piperidines; Potassium; Rats; Rats, Inbred Strains; Temperature | 1997 |
Interaction of a thrombin inhibitor and a platelet GP IIb/IIIa antagonist in vivo: evidence that thrombin mediates platelet aggregation and subsequent thromboxane A2 formation during coronary thrombolysis.
Topics: Acetates; Animals; Antithrombins; Coronary Vessels; Dogs; Drug Interactions; Naphthalenes; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin; Thromboxane A2; Tyrosine | 1997 |
Degradation of morpholine by an environmental Mycobacterium strain involves a cytochrome P-450.
Topics: Acetates; Biodegradation, Environmental; Carbon Monoxide; Cytochrome P-450 Enzyme System; Ethanolamine; Ethylamines; Glycolates; Hydrogen; Industrial Waste; Magnetic Resonance Spectroscopy; Metyrapone; Morpholines; Mycobacterium; Piperidines; Pyrrolidines; Sewage; Succinic Acid | 1998 |
Association between ligand-induced conformational changes of integrin IIbbeta3 and IIbbeta3-mediated intracellular Ca2+ signaling.
Topics: Acetates; Antibodies, Monoclonal; Benzamidines; Calcium Signaling; Dipeptides; Humans; Intracellular Fluid; Molecular Structure; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Conformation; Structure-Activity Relationship; Tirofiban; Tyrosine; Valerates | 1998 |
Human cerebral acetylcholinesterase activity measured with positron emission tomography: procedure, normal values and effect of age.
Topics: Acetates; Acetylcholinesterase; Adult; Aged; Aged, 80 and over; Aging; Brain; Carbon Radioisotopes; Cerebral Cortex; Chromatography, Thin Layer; Female; Humans; Male; Middle Aged; Nerve Degeneration; Piperidines; Reference Values; Thalamus; Tomography, Emission-Computed | 1999 |
Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Lamotrigine; Male; Motor Activity; Pain Measurement; Phenols; Piperidines; Pyrrolidinones; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Triazines | 1999 |
Combination of donepezil and gabapentin for behavioral disorders in Alzheimer's disease.
Topics: Acetates; Aged; Aged, 80 and over; Alzheimer Disease; Amines; Anticonvulsants; Cholinesterase Inhibitors; Cyclohexanecarboxylic Acids; Donepezil; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Indans; Male; Mental Disorders; Piperidines; Psychiatric Status Rating Scales; Treatment Outcome | 2000 |
Comparison of the efficiency of various coupling systems in the acylation of model secondary amines with thymin-1-ylacetic acid.
Topics: Acetates; Acylation; Amines; Carbodiimides; Hydrocarbons, Brominated; Indicators and Reagents; Peptide Nucleic Acids; Piperidines; Proline; Thymine | 1999 |
Quinazolone-alkyl-carboxylic acid derivatives inhibit transmembrane Ca(2+) ion flux to (+)-(S)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid.
Topics: Acetates; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Calcium; Calcium Channels; Cell Membrane; Cerebral Cortex; Excitatory Amino Acid Agents; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Ion Channel Gating; Ligands; Male; Models, Molecular; Molecular Structure; Piperidines; Propionates; Quinazolines; Rats; Rats, Wistar; Receptors, AMPA; Structure-Activity Relationship | 2001 |
PET measurement of cerebral acetylcholine esterase activity without blood sampling.
Topics: Acetates; Acetylcholinesterase; Aged; Algorithms; Alzheimer Disease; Basal Ganglia; Brain; Female; Humans; Lewy Body Disease; Male; Middle Aged; Piperidines; Radiopharmaceuticals; Tomography, Emission-Computed | 2001 |
Gabapentin inhibits the substance P-facilitated K(+)-evoked release of [(3)H]glutamate from rat caudial trigeminal nucleus slices.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neurokinin-1 Receptor Antagonists; Organ Culture Techniques; Piperidines; Potassium; Pregabalin; Rats; Rats, Inbred Strains; Stereoisomerism; Substance P; Trigeminal Nucleus, Spinal; Tritium | 2001 |
In-vivo measurements of regional acetylcholine esterase activity in degenerative dementia: comparison with blood flow and glucose metabolism.
Topics: Acetates; Acetylcholinesterase; Aged; Alzheimer Disease; Brain; Brain Stem; Carbon Radioisotopes; Cerebellum; Cerebrovascular Circulation; Corpus Striatum; Female; Glucose; Humans; Lewy Body Disease; Male; Mental Status Schedule; Middle Aged; Piperidines; Reference Values; Regression Analysis; Thalamus; Tomography, Emission-Computed | 2000 |
Formation of gas-phase clusters monitored during electrospray mass spectrometry: a study of quaternary ammonium pesticides.
Topics: Acetates; Cations; Chlorides; Chlormequat; Chromatography, Liquid; Diquat; Molecular Structure; Paraquat; Pesticides; Piperidines; Pyrazoles; Quaternary Ammonium Compounds; Spectrometry, Mass, Electrospray Ionization | 2001 |
Effects of tachykinin NK1 receptor antagonists on the viscerosensory response caused by colorectal distention in rabbits.
Topics: Acetates; Animals; Catheterization; Central Nervous System; Colon; Irritants; Male; Naphthyridines; Neurokinin-1 Receptor Antagonists; Pain; Peripheral Nervous System; Physical Stimulation; Piperidines; Rabbits; Rectum; Sensation | 2002 |
Analysis of uptake and release of newly synthesized acetylcholine in PC12 cells overexpressing the rat vesicular acetylcholine transporter (VAChT).
Topics: Acetates; Acetylcholine; Animals; Brain Chemistry; Carbon Radioisotopes; Carrier Proteins; Central Nervous System; Choline; Choline O-Acetyltransferase; Clone Cells; Cloning, Molecular; Gene Expression Regulation; Membrane Potentials; Membrane Transport Proteins; Neuromuscular Depolarizing Agents; PC12 Cells; Piperidines; Potassium; Presynaptic Terminals; Rats; Subcellular Fractions; Synaptic Membranes; Synaptic Transmission; Synaptic Vesicles; Transfection; Vesicular Acetylcholine Transport Proteins; Vesicular Transport Proteins | 2002 |
Synthesis and preliminary evaluation of [18F]FEtP4A, a promising PET tracer for mapping acetylcholinesterase in vivo.
Topics: Acetates; Acetylcholinesterase; Animals; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Fluorine Radioisotopes; Mice; Piperidines; Radionuclide Imaging; Sensitivity and Specificity; Tissue Distribution | 2002 |
Gabapentin and the neurokinin(1) receptor antagonist CI-1021 act synergistically in two rat models of neuropathic pain.
Topics: Acetates; Amines; Animals; Benzofurans; Carbamates; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Neurokinin-1 Receptor Antagonists; Pain; Pain Measurement; Peripheral Nervous System Diseases; Piperidines; Rats; Rats, Sprague-Dawley | 2002 |
Large-amplitude 5-HT1A receptor activation: a new mechanism of profound, central analgesia.
Topics: Acetates; Adrenergic Uptake Inhibitors; Amines; Aminopyridines; Analgesia; Analgesics; Animals; Cells, Cultured; CHO Cells; Cricetinae; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Synergism; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Hyperalgesia; Imipramine; Ketamine; Male; Morphine; Pain; Pain Measurement; Pain Threshold; Piperidines; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Time Factors; Transfection | 2002 |
N-[18F]fluoroethyl-4-piperidyl acetate ([18F]FEtP4A): A PET tracer for imaging brain acetylcholinesterase in vivo.
Topics: Acetates; Acetylcholinesterase; Animals; Autoradiography; Brain; Carbon Radioisotopes; Fluorine Radioisotopes; Hydrolysis; Macaca mulatta; Male; Piperidines; Radiopharmaceuticals; Rats; Sensitivity and Specificity; Tomography, Emission-Computed | 2003 |
[Synthesis of spasmolytic alkanolamine esters of alpha-phenyl-alpha-piperidine acetic acid].
Topics: Acetates; Esters; Parasympatholytics; Piperidines | 1953 |
[Synthesis of various alpha-alkyl-alpha-piperidineacetic acid esters. 7. Synthesis of spasmolytic substances].
Topics: Acetates; Esters; Parasympatholytics; Piperidines | 1953 |
[Ritalin, a new synthetic compound with specific analeptic components].
Topics: Acetates; Central Nervous System; Central Nervous System Stimulants; Methylphenidate; Piperidines | 1954 |
[(2-Diphenylmethyl-piperidine hydrochloride and the methyl ester of 2-chloro-2-phenyl-2-(2-piperidyl)-acetic acid), drugs with waking effect in anesthesia].
Topics: Acetates; Anesthesia; Anesthesiology; Piperidines | 1955 |
[Studies on insecticides. VII. Synthesis of 1-benzyl-2-oxo-5-isopropyl-4-piperidineacetic acid].
Topics: Acetates; Insecticides; Oxotremorine; Piperidines | 1963 |
[Acetolysis of omega-N-piperidino-propiophenone and 1-N-piperidino-3-butanone].
Topics: Acetates; Butanones; Ketones; Piperidines; Propiophenones | 1963 |
[ACETOLYSIS OF 2-PIPERIODONOMETHYLCYCLOHEPTANONE. 3. ACETOLYSIS OF MANNICH BASES].
Topics: Acetates; Chemistry, Pharmaceutical; Ketones; Mannich Bases; Piperidines; Research | 1964 |
[EXPERIMENTAL RESEARCH ON A NEW ANTISPASMODIC ANALGESIC: 2-PIPERIDINOETHYL 2-PHENYL-2-(1-PIPERIDONO)-ACETATE DI-HC1)].
Topics: Acetates; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Mice; Muscle Relaxants, Central; Parasympatholytics; Pharmacology; Piperidines; Research; Toxicology | 1964 |
[ON THE USE OF A NEW ANTISPASTIC: ALPHA-PHENYL-ALPHA-(1-PIPERIDINE)-ACETATE OF BETA-PIPERIDINO-ETHYL-DIHYDROCHLORIDE, IN LABOR].
Topics: Acetates; Female; Humans; Labor, Obstetric; Muscle Relaxants, Central; Piperidines; Pregnancy | 1965 |
Peptic ulcer management with JB 323 (piptal) a new anticholinergic.
Topics: Acetates; Cholinergic Antagonists; Humans; Parasympatholytics; Peptic Ulcer; Piperidines | 1955 |
In vivo study of acetylcholine esterase in basal forebrain, amygdala, and cortex in mild to moderate Alzheimer disease.
Topics: Acetates; Acetylcholinesterase; Aged; Alzheimer Disease; Amygdala; Basal Nucleus of Meynert; Blood Glucose; Carbon Radioisotopes; Cerebral Cortex; Cholinergic Fibers; Female; Fluorodeoxyglucose F18; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Piperidines; Tomography, Emission-Computed | 2004 |
Antagonists of human CCR5 receptor containing 4-(pyrazolyl)piperidine side chains. Part 2: Discovery of potent, selective, and orally bioavailable compounds.
Topics: Acetates; Administration, Oral; Animals; Anti-HIV Agents; Biological Availability; CCR5 Receptor Antagonists; Dogs; HeLa Cells; Humans; Macaca mulatta; Molecular Structure; Monocytes; Piperidines; Pyrazoles; Rats; Structure-Activity Relationship | 2004 |
Syntheses of (+)- and (-)-dihydropinidine and (+)- and (-)-epidihydropinidine by using yeast reduction of methyl (2-oxocyclohexyl)acetate.
Topics: Acetates; Cyclohexanones; Molecular Structure; Oxidation-Reduction; Piperidines; Saccharomyces cerevisiae | 2004 |
Syntheses and SAR studies of 4-(heteroarylpiperdin-1-yl-methyl)-pyrrolidin-1-yl-acetic acid antagonists of the human CCR5 chemokine receptor.
Topics: Acetates; Anti-HIV Agents; Binding Sites; CCR5 Receptor Antagonists; Cell Division; HeLa Cells; HIV-1; Humans; Piperidines; Pyrrolidines; Structure-Activity Relationship | 2004 |
Elimination-addition mechanism for nucleophilic substitution reaction of cyclohexenyl iodonium salts and regioselectivity of nucleophilic addition to the cyclohexyne intermediate.
Topics: Acetates; Alkenes; Alkynes; Cyclohexanes; Deuterium; Kinetics; Molecular Structure; Onium Compounds; Oxidation-Reduction; Piperidines; Stereoisomerism | 2004 |
Anatalline and other methyl jasmonate-inducible nicotine alkaloids from Nicotiana tabacum cv. By-2 cell cultures.
Topics: Acetates; Alkaloids; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclopentanes; Gas Chromatography-Mass Spectrometry; Humans; Magnetic Resonance Spectroscopy; Nicotiana; Nicotine; Oxylipins; Phytotherapy; Piperidines; Plant Leaves; Pyridines | 2004 |
N-[18F] fluoroethylpiperidin-4ylmethyl acetate, a novel lipophilic acetylcholine analogue for PET measurement of brain acetylcholinesterase activity.
Topics: Acetates; Acetylcholine; Acetylcholinesterase; Animals; Blood-Brain Barrier; Brain; Cholinesterase Inhibitors; Fluorine Radioisotopes; Humans; Hydrolysis; In Vitro Techniques; Male; Membranes, Artificial; Permeability; Piperidines; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Wistar; Structure-Activity Relationship; Tissue Distribution | 2005 |
The ventral tegmental area as a putative target for tachykinins in cardiovascular regulation.
Topics: Acetates; Adrenergic beta-Antagonists; Animals; Atenolol; Behavior, Animal; Benzamides; Benzazepines; Blood Pressure; Dopamine D2 Receptor Antagonists; Glutamic Acid; Heart Rate; Indoles; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Quinolines; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Ventral Tegmental Area | 2005 |
Rapid and sensitive LC/MS/MS analysis of the novel tyrosine kinase inhibitor ZD6474 in mouse plasma and tissues.
Topics: Acetates; Animals; Antineoplastic Agents; Calibration; Chemistry, Pharmaceutical; Chromatography; Chromatography, Liquid; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Humans; Ions; Liver; Mass Spectrometry; Mice; Mice, Inbred BALB C; Models, Chemical; Neoplasms; Pentanes; Piperidines; Protein-Tyrosine Kinases; Quinazolines; Reproducibility of Results; Sensitivity and Specificity; Time Factors; Tissue Distribution; Trazodone | 2005 |
Neural and non-neural mediation of propionate-induced contractile responses in the rat distal colon.
Topics: Acetates; Anesthetics, Local; Animals; Atropine; Butyrates; Colon; Cyclooxygenase Inhibitors; Dioxanes; Dose-Response Relationship, Drug; Enteric Nervous System; Fatty Acids, Volatile; Intestinal Mucosa; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Organ Culture Techniques; Piperidines; Piroxicam; Propionates; Rats; Receptors, Serotonin; Serotonin Antagonists | 2005 |
Improved synthesis and radiolabeling of [11C]MP4A, a suitable ligand for the investigation of the cholinergic system using PET.
Topics: Acetates; Acetylation; Acetylcholinesterase; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Hydrocarbons, Iodinated; Isotope Labeling; Magnetic Resonance Spectroscopy; Piperidines; Positron-Emission Tomography; Radiopharmaceuticals | 2006 |
Synthesis, biological evaluation, and pharmacokinetic study of prolyl-1-piperazinylacetic acid and prolyl-4-piperidinylacetic acid derivatives as VLA-4 antagonists.
Topics: Acetates; Animals; Dogs; Integrin alpha4beta1; Magnetic Resonance Spectroscopy; Male; Piperazines; Piperidines; Proline; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Fast Atom Bombardment | 2006 |
Upregulation of tachykinin NK-1 and NK-3 receptor binding sites in the spinal cord of spontaneously hypertensive rat: impact on the autonomic control of blood pressure.
Topics: Acetates; Animals; Autonomic Nervous System; Autoradiography; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Indoles; Injections, Spinal; Male; Peptide Fragments; Piperidines; Quinolines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Spinal Cord; Substance P; Thoracic Vertebrae; Up-Regulation | 2006 |
In vitro and in vivo evaluation of novel ligands for radioimmunotherapy.
Topics: Acetates; Animals; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Chelating Agents; Drug Design; Female; Glycine; Isotope Labeling; Metabolic Clearance Rate; Mice; Mice, Nude; Organ Specificity; Piperidines; Radioimmunotherapy; Radiopharmaceuticals; Tissue Distribution | 2006 |
Divergent asymmetric synthesis of 3,5-disubstituted piperidines.
Topics: Acetates; Alcohols; Catalysis; Enzymes; Hydroxy Acids; Oxygen; Piperidines; Ruthenium | 2006 |
Arthritis clinical trial results revealed.
Topics: Acetates; Antirheumatic Agents; Arthritis, Rheumatoid; Chondroitin Sulfates; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Osteoarthritis; Piperidines; Pyrimidines; Pyrroles | 2007 |
Antitumor and antibacterial activity of ethylacetate extract of Ludwigia hyssopifolia linn and its active principle piperine.
Topics: Acetates; Agrobacterium tumefaciens; Alkaloids; Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Benzodioxoles; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Onagraceae; Piperidines; Plant Extracts; Plant Tumors; Polyunsaturated Alkamides; Solvents | 2007 |
Synergy between a NR2B receptor antagonist DHQ and 3-methyl-gabapentin in mice with neuropathic pain.
Topics: Acetates; Animals; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Male; Mice; Piperidines; Quinolones; Receptors, N-Methyl-D-Aspartate; Sciatic Neuropathy | 2008 |
In vivo evaluation of N-[18F]fluoroethylpiperidin-4ylmethyl acetate in rats compared with MP4A as a probe for measuring cerebral acetylcholinesterase activity.
Topics: Acetates; Acetylcholinesterase; Animals; Cerebral Cortex; Male; Models, Neurological; Piperidines; Positron-Emission Tomography; Rats; Rats, Wistar; Time Factors; Tissue Distribution | 2010 |
Fluorinated piperidine acetic acids as gamma-secretase modulators.
Topics: Acetates; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Diazonium Compounds; Disease Models, Animal; Fluorine; Mice; Mice, Transgenic; Peptide Fragments; Piperidines; Rats; Receptors, Notch | 2010 |
Piperidine-derived gamma-secretase modulators.
Topics: Acetates; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Cell Line, Tumor; Dogs; Humans; Mice; Peptide Fragments; Piperidines; Rats; Structure-Activity Relationship; Substrate Specificity | 2010 |
TASTPM mice expressing amyloid precursor protein and presenilin-1 mutant transgenes are sensitive to γ-secretase modulation and amyloid-β₄₂ lowering by GSM-10h.
Topics: Acetates; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Cell Death; Cerebral Cortex; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Mice; Mice, Transgenic; Neurons; Peptide Fragments; Piperidines; Presenilin-1; RNA, Messenger; Transgenes | 2011 |
Tipepidine enhances the antinociceptive-like action of carbamazepine in the acetic acid writhing test.
Topics: Acetates; Analgesics; Animals; Behavior, Animal; Carbamazepine; Drug Synergism; Male; Mice; Piperidines | 2011 |
Effect of radiolabeled metabolite elimination from the brain on the accuracy of cerebral enzyme activity estimation using positron emission tomography with substrate tracers.
Topics: Acetates; Acetylcholinesterase; Algorithms; Animals; Brain; Computer Simulation; Fluorine Radioisotopes; Least-Squares Analysis; Macaca mulatta; Male; Monte Carlo Method; Nonlinear Dynamics; Piperidines; Positron-Emission Tomography; Radiopharmaceuticals | 2011 |
Reduced acetylcholinesterase activity in the fusiform gyrus in adults with autism spectrum disorders.
Topics: Acetates; Acetylcholinesterase; Adolescent; Adult; Brain Mapping; Carbon Radioisotopes; Child; Child Development Disorders, Pervasive; Communication; Female; Humans; Image Processing, Computer-Assisted; Male; Piperidines; Positron-Emission Tomography; Reference Values; Social Behavior; Stereotyped Behavior; Temporal Lobe; Young Adult | 2011 |
Dynamics of Aβ42 reduction in plasma, CSF and brain of rats treated with the γ-secretase modulator, GSM-10h.
Topics: Acetates; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Basic Helix-Loop-Helix Transcription Factors; Brain Chemistry; Cell Count; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Homeodomain Proteins; Male; Neurons; Peptide Fragments; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Notch; RNA, Messenger; Signal Transduction; Thymus Gland; Transcription Factor HES-1 | 2011 |
Cholinergic dysfunction after traumatic brain injury: preliminary findings from a PET study.
Topics: Acetates; Acetylcholinesterase; Adult; Brain; Brain Injuries; Brain Mapping; Carbon Radioisotopes; Cognition Disorders; Female; Humans; Male; Middle Aged; Piperidines; Positron-Emission Tomography; Radioligand Assay | 2011 |
Evaluation of CYP2C8 inhibition in vitro: utility of montelukast as a selective CYP2C8 probe substrate.
Topics: Acetates; Amodiaquine; Aryl Hydrocarbon Hydroxylases; Binding Sites; Carbamates; Cyclopropanes; Cytochrome P-450 CYP2C8; Drug Interactions; Humans; Microsomes, Liver; Paclitaxel; Piperidines; Quinolines; Rosiglitazone; Sensitivity and Specificity; Substrate Specificity; Sulfides; Thiazolidinediones | 2011 |
Stable aluminium fluoride chelates with triazacyclononane derivatives proved by X-ray crystallography and 18F-labeling study.
Topics: Acetates; Aluminum Compounds; Animals; Aza Compounds; Chelating Agents; Crystallography, X-Ray; Fluorides; Fluorine Radioisotopes; Isotope Labeling; Mice; Models, Molecular; Molecular Conformation; Piperidines | 2011 |
Radical-mediated nitrile translocation as the key step in the stereoselective transformation of 2-(4-chloro-2-cyanobutyl)aziridines to methyl cis-(1-arylmethyl-4-phenylpiperidin-2-yl)acetates.
Topics: Acetates; Aziridines; Methylation; Nitriles; Piperidines; Stereoisomerism | 2012 |
[11C]-MP4A PET cholinergic measurements in amnestic mild cognitive impairment, probable Alzheimer's disease, and dementia with Lewy bodies: a Bayesian method and voxel-based analysis.
Topics: Acetates; Acetylcholinesterase; Aged; Aged, 80 and over; Amnesia; Bayes Theorem; Carbon Radioisotopes; Cognitive Dysfunction; Female; Humans; Lewy Body Disease; Male; Middle Aged; Piperidines; Positron-Emission Tomography | 2012 |
A method to predict the ratio of the tracer conversion rate to the tracer back-diffusion rate of an irreversible-type radiotracer in humans by preclinical evaluations.
Topics: Acetates; Acetylcholinesterase; Animals; Cerebral Cortex; Diffusion; Humans; Kinetics; Models, Biological; Piperidines; Positron-Emission Tomography; Propionates; Radioactive Tracers; Rats; Reproducibility of Results; Species Specificity | 2012 |
Peptidomimetics as potent and selective PTP1B inhibitors.
Topics: Acetates; Amides; Dipeptides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Models, Molecular; Molecular Structure; Peptidomimetics; Piperidines; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Structure-Activity Relationship; Substrate Specificity | 2013 |
Amelioration of cognitive deficits in plaque-bearing Alzheimer's disease model mice through selective reduction of nascent soluble Aβ42 without affecting other Aβ pools.
Topics: Acetates; Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Antibodies; Chromatography, Liquid; Cognition Disorders; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Hippocampus; Humans; Mass Spectrometry; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Peptide Fragments; Piperidines | 2013 |
Non-input analysis for incomplete trapping irreversible tracer with PET.
Topics: Acetates; Kinetics; Monte Carlo Method; Piperidines; Positron-Emission Tomography; Radioactive Tracers | 2013 |
Cholinergic activity correlates with reserve proxies in Alzheimer's disease.
Topics: Acetates; Acetylcholine; Aged; Aged, 80 and over; Alzheimer Disease; Carbon Isotopes; Cognitive Dysfunction; Cognitive Reserve; Educational Status; Employment; Female; Fluorodeoxyglucose F18; Humans; Male; Mental Status Schedule; Middle Aged; Piperidines; Positron-Emission Tomography; Radiography; Statistics, Nonparametric; Tomography Scanners, X-Ray Computed | 2013 |
One-pot multicomponent synthesis of highly functionalized piperidines from substituted β-nitrostyrenes, Meldrum's acid, aromatic aldehydes, and ammonium acetate.
Topics: Acetates; Aldehydes; Combinatorial Chemistry Techniques; Dioxanes; Molecular Structure; Piperidines; Styrenes | 2014 |
The integrity of the cholinergic system determines memory performance in healthy elderly.
Topics: Acetates; Acetylcholinesterase; Aged; Aging; Cerebral Cortex; Female; Humans; Magnetic Resonance Imaging; Male; Memory, Episodic; Middle Aged; Piperidines; Positron-Emission Tomography | 2014 |
Mosquito odorant receptor for DEET and methyl jasmonate.
Topics: Acetates; Aldehydes; Animals; Arthropod Antennae; Avoidance Learning; beta-Alanine; Cloning, Molecular; Culex; Cyclohexane Monoterpenes; Cyclopentanes; DEET; Electrophysiology; Feeding Behavior; Female; Insect Repellents; Menthol; Models, Neurological; Molecular Sequence Data; Oocytes; Oxylipins; Piperidines; Receptors, Ionotropic Glutamate; Receptors, Odorant; Recombinant Fusion Proteins; RNA Interference; Smell; Transcription, Genetic; Xenopus laevis | 2014 |
Structure-activity relationships (SAR) and structure-kinetic relationships (SKR) of pyrrolopiperidinone acetic acids as CRTh2 antagonists.
Topics: Acetates; Administration, Oral; Animals; Caco-2 Cells; Cell Membrane Permeability; Half-Life; Humans; Piperidines; Pyrazoles; Rats; Receptors, Immunologic; Receptors, Prostaglandin; Structure-Activity Relationship | 2014 |
Antiallergic effect of piperine on ovalbumin-induced allergic rhinitis in mice.
Topics: Acetates; Alkaloids; Animals; Anti-Allergic Agents; Benzodioxoles; Biomarkers; Cell Degranulation; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Eosinophils; Histamine; Immunoglobulin E; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Mast Cells; Nitric Oxide; Ovalbumin; Piperidines; Polyunsaturated Alkamides; Quinolines; Rhinitis, Allergic; Spleen; Sulfides; Time Factors | 2015 |
Diastereo- and Enantioselective Iridium Catalyzed Coupling of Vinyl Aziridines with Alcohols: Site-Selective Modification of Unprotected Diols and Synthesis of Substituted Piperidines.
Topics: 2-Propanol; Acetates; Alcohols; Aldehydes; Allyl Compounds; Aziridines; Catalysis; Iridium; Oxidation-Reduction; Piperidines; Stereoisomerism; Vinyl Compounds | 2015 |
Quantitative Signaling and Structure-Activity Analyses Demonstrate Functional Selectivity at the Nociceptin/Orphanin FQ Opioid Receptor.
Topics: Acetates; Benzimidazoles; HEK293 Cells; Humans; Narcotic Antagonists; Nociceptin Receptor; Piperidines; Protein Binding; Receptors, Opioid; Spiro Compounds; Structure-Activity Relationship | 2015 |
Trifloxystrobin-induced mitophagy through mitochondrial damage in human skin keratinocytes.
Topics: Acetates; Autophagy; Cell Line; Dose-Response Relationship, Drug; Free Radical Scavengers; Fungicides, Industrial; Humans; Imines; Keratinocytes; Membrane Potential, Mitochondrial; Methacrylates; Mitochondria; Mitophagy; Organophosphorus Compounds; Piperidines; Protein Kinases; Strobilurins; Ubiquitin-Protein Ligases; Up-Regulation | 2016 |
White matter lesions and the cholinergic deficit in aging and mild cognitive impairment.
Topics: Acetates; Acetylcholinesterase; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cognitive Dysfunction; Female; Humans; Male; Memory; Middle Aged; Neuropsychological Tests; Piperidines; Positron-Emission Tomography; White Matter | 2017 |
Estimation of the Contribution of CYP2C8 and CYP3A4 in Repaglinide Metabolism by Human Liver Microsomes Under Various Buffer Conditions.
Topics: Acetates; Buffers; Carbamates; Cyclopropanes; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inducers; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Humans; Hypoglycemic Agents; Ketoconazole; Microsomes, Liver; Piperidines; Quinolines; Sulfides | 2017 |
Synergistic inhibition of Aβ production by combinations of γ-secretase modulators.
Topics: Acetates; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Cell Line, Tumor; Drug Synergism; Humans; Mice; Peptide Fragments; Piperidines; Protease Inhibitors | 2017 |
Trace level determination of chloroacetyl chloride and degradation products by derivatization gas chromatography.
Topics: Acetates; Chromatography, Gas; Ethylene Dichlorides; Flame Ionization; Limit of Detection; Piperidines | 2018 |
Effect of cholinergic treatment depends on cholinergic integrity in early Alzheimer's disease.
Topics: Acetates; Acetylcholinesterase; Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cerebral Cortex; Cholinergic Agents; Cognitive Dysfunction; Female; Humans; Magnetic Resonance Imaging; Male; Mental Status Schedule; Middle Aged; Neuropsychological Tests; Oxygen; Piperidines; Positron-Emission Tomography; Rivastigmine | 2018 |
A novel flurophore-cyano-carboxylic-Ag microhybrid: Enhanced two photon absorption for two-photon photothermal therapy of HeLa cancer cells by targeting mitochondria.
Topics: Acetates; Acetonitriles; Carbazoles; Cell Survival; Dose-Response Relationship, Drug; Fluorescent Dyes; HeLa Cells; Humans; Metal Nanoparticles; Mitochondria; Photons; Phototherapy; Piperidines; Silver; Surface Plasmon Resonance | 2018 |
Voxel-Based Acetylcholinesterase PET Study in Early and Late Onset Alzheimer's Disease.
Topics: Acetates; Acetylcholinesterase; Age of Onset; Aged; Aging; Alzheimer Disease; Brain; Brain Mapping; Carbon Radioisotopes; Female; Humans; Male; Middle Aged; Piperidines; Positron-Emission Tomography; Radiopharmaceuticals | 2018 |
Isolation from Stevia rebaudiana of DMDP acetic acid, a novel iminosugar amino acid: synthesis and glycosidase inhibition profile of glycine and β-alanine pyrrolidine amino acids.
Topics: Acetates; alpha-Galactosidase; Amino Acids; beta-Alanine; beta-Galactosidase; Enzyme Inhibitors; Gas Chromatography-Mass Spectrometry; Glycine; Glycoside Hydrolases; Glycosides; Hydroxyproline; Imino Sugars; Piperidines; Propionates; Pyrrolidines; Stevia | 2019 |
Concomitant bilastine and montelukast as additive therapy for seasonal allergic rhinoconjunctivits and mild-to-moderate asthma. The SKY study.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Benzimidazoles; Cyclopropanes; Humans; Piperidines; Quinolines; Seasons; Sulfides | 2020 |
Spatial distributions of cholinergic impairment and neuronal hypometabolism differ in MCI due to AD.
Topics: Acetates; Acetylcholinesterase; Aged; Aged, 80 and over; Alzheimer Disease; Cognitive Dysfunction; Female; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Piperidines; Positron-Emission Tomography; Radiopharmaceuticals | 2019 |
One-pot five-component high diastereoselective synthesis of polysubstituted 2-piperidinones from aromatic aldehydes, nitriles, dialkyl malonates and ammonium acetate.
Topics: Acetates; Acinetobacter baumannii; Aldehydes; Catalysis; Malonates; Nitriles; Piperidines; Piperidones; Staphylococcus aureus; Stereoisomerism | 2020 |
Potential synergistic effects of novel hematopoietic prostaglandin D synthase inhibitor TAS-205 and different types of anti-allergic medicine on nasal obstruction in a Guinea pig model of experimental allergic rhinitis.
Topics: Acetates; Animals; Anti-Allergic Agents; Cell Line; Cyclopropanes; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Guinea Pigs; Humans; Intramolecular Oxidoreductases; Lipocalins; Male; Morpholines; Nasal Mucosa; Nasal Obstruction; Ovalbumin; Piperidines; Prostaglandin D2; Pyrroles; Quality of Life; Quinolines; Rats; Rhinitis, Allergic; Sulfides; Terfenadine | 2020 |
Spray dried solid dispersion of repaglinide using hypromellose acetate succinate:
Topics: Acetates; Animals; Carbamates; Chemistry, Pharmaceutical; Hypromellose Derivatives; Pharmaceutical Preparations; Piperidines; Rats; Solubility; Succinates | 2020 |
Risk Assessment-Based Enhanced Analytical Quality-by-Design Approach to Eco-Friendly and Economical Multicomponent Spectrophotometric Methods for Simultaneous Estimation of Montelukast Sodium and Bilastine.
Topics: Acetates; Benzimidazoles; Cyclopropanes; Piperidines; Quinolines; Risk Assessment; Sulfides | 2021 |
Risk and DoE-Based Analytical Failure Mode Effect Analysis (AFMEA) to Simultaneous Estimation of Montelukast Sodium and Bilastine by HPTLC Method Using Enhanced AQbD Approach.
Topics: Acetates; Benzimidazoles; Chromatography, Thin Layer; Cyclopropanes; Humans; Piperidines; Quinolines; Research Design; Sulfides | 2022 |
Difelikefalin Acetate.
Topics: Acetates; Humans; Piperidines | 2022 |