phenyl acetate has been researched along with montelukast in 1741 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 82 (4.71) | 18.2507 |
| 2000's | 854 (49.05) | 29.6817 |
| 2010's | 614 (35.27) | 24.3611 |
| 2020's | 191 (10.97) | 2.80 |
| Authors | Studies |
|---|---|
| Belley, M; Champion, E; Charette, L; Evans, J; Ford-Hutchinson, AW; Gauthier, JY; Jones, TR; Labelle, M; Lord, A; Masson, P | 1 |
| Amin, RD; Cheng, H; Rogers, JD | 1 |
| Amin, R; Cheng, H; De Smet, M; Larson, P; Margolskee, D; Reiss, T; Schoors, DF; Somers, G | 1 |
| Amin, R; Cheng, H; De Smet, M; Gertz, BJ; Leff, JA; Malbecq, W; Meisner, D; Noonan, N; Rogers, JD; Somers, G | 1 |
| Altman, LC; Bewtra, A; Chervinsky, P; Kundu, S; Noonan, GP; Reiss, TF; Stricker, WE; Zhang, J | 1 |
| Botto, A; De Lepeleire, I; Decramer, M; Kundu, S; Reiss, TF; Rochette, F; Zhang, J | 1 |
| Botto, A; Busse, WW; Kundu, S; Reiss, TF; Sorkness, CA; Stricker, W; Zhang, J | 1 |
| Egan, R; Walden, S; Wang, T | 1 |
| Cheng, H; Liu, L; Rogers, JD; Zhao, JJ | 1 |
| Balani, SK; Chiba, M; Lin, JH; Nishime, JA; Xu, X | 1 |
| Amin, RD; Arison, BH; Baillie, TA; Balani, SK; Chiba, M; Doss, GA; Dufresne, C; Freeman, A; Gertz, BJ; Holland, SD; Isenberg, JI; Koss, MA; Lasseter, KC; Lin, JH; Miller, RR; Pratha, V; Rogers, JD; Schwartz, JI; Xu, X | 1 |
| Bronsky, EA; Guerreiro, D; Kemp, JP; Reiss, TF; Zhang, J | 1 |
| Amin, RD; Cheng, H; Freeman, A; Haesen, R; Holland, SD; Larson, P; Merz, M; Rogers, JD; Seiberling, M; Zhao, JJ | 1 |
| Gallant, M; Metters, KM; Sawyer, N; Zamboni, RJ | 1 |
| Bronsky, E; Guerreiro, D; Harman, E; Hendeles, L; Hill, JB; Reiss, TF; Tanaka, WK; Zhang, J | 1 |
| Massie, RJ | 1 |
| Tan, RA | 1 |
| Becker, A; Bernstein, JA; Knorr, B; Matz, J; Nguyen, H; Reiss, TF; Seidenberg, BC | 1 |
| Anderson, GP; Ball, HA; Beck, A; Bittiger, H; Bray, MA; Felner, A; Gentsch, C; Gerspacher, M; Giese, K; Hauser, K; Kraetz, J; Niederhauser, U; Subramanian, N; Vassout, A; von Sprecher, A | 1 |
| Chervinsky, P; Dockhorn, RJ; Edwards, TB; Reiss, TF; Seidenberg, B; Shingo, S | 1 |
| Aharony, D | 1 |
| Bernstein, PR | 1 |
| Brandon, M; Chervinsky, P; Kundu, S; McBurney, J; Noonan, MJ; Reiss, TF; Zhang, J | 1 |
| Bronsky, EA; Busse, WW; Dockhorn, R; Hendeles, L; Kemp, J; Kundu, S; Leff, JA; Pearlman, D; Reiss, TF; Seidenberg, BC; Zhang, J | 1 |
| Hansen-Flaschen, J; Schotland, H | 1 |
| Breznay, JB; Ellsworth, A | 1 |
| Altman, LC; Munk, Z; Noonan, N; Reiss, TF; Seltzer, J; Shingo, S; Zhang, J | 1 |
| Faulds, D; Markham, A | 1 |
| Dockhorn, RJ; Kemp, JP; Knorr, B; Nguyen, HH; Reiss, TF; Seidenberg, BC; Shapiro, GG | 1 |
| Hara, K; Kamei, T; Ochiai, H; Takano, T; Uchiyama, N | 1 |
| Lawyer, C | 1 |
| Adelman, A | 1 |
| Lane, SJ | 1 |
| Jébrak, G | 1 |
| Honig, PK; Jenkins, JK | 1 |
| Stempel, DA | 4 |
| Dufresne, C; Gauthier, JY; Guay, D; Jones, TR; McAuliffe, M; McFarlane, C; Metters, KM; Prasit, P; Rochette, C; Roy, P; Sawyer, N; Zamboni, R | 1 |
| Lipworth, BJ | 2 |
| De Smet, M; Diamant, Z; Grootendorst, DC; Leff, JA; Peszek, I; Seidenberg, BC; Sterk, PJ; Timmers, MC; Veselic-Charvat, M; Zwinderman, AH | 1 |
| Rosenwasser, LJ | 1 |
| Guerra, J; Malmstrom, K; Piñeiro, A; Reiss, TF; Rodriguez-Gomez, G; Seidenberg, BC; Villaran, C; Wei, LX | 1 |
| Bachmann, K; Ebel, D; Huhn, RD; Hunt, TL; Jauregui, L; Larson, P; Malmstrom, K; Miller, K; Peszek, I; Reese, JH; Reiss, TF; Schwartz, J; Scott, M; Shingo, S; Sullivan, TJ | 1 |
| Davis, WM; Waters, IW | 1 |
| Arnout, J; De Lepeleire, I; De Schepper, PJ; Depré, M; Freeman, A; Gertz, B; Holland, S; Van Hecken, A; Verbesselt, R; Wong, PH; Wynants, K | 1 |
| Artés, MJ; Franco, J | 1 |
| Mallet, JP | 1 |
| Jones, TR; Rodger, IW | 1 |
| Enrique, E; Gaig, P; García-Ortega, P; San Miguel, MM | 1 |
| Capizzi, T; Finn, AF; Godard, P; Israel, E; Kundu, S; Leff, JA; Löfdahl, CG; Noonan, MJ; Reiss, TF; Seidenberg, BC | 1 |
| Matthys, H; Virchow, JC | 1 |
| Richardson, CR | 1 |
| Amin, RD; Blake, K; Chervinsky, P; Freeman, A; Gertz, BJ; Haesen, R; Holland, S; Knorr, B; Larson, P; Michiels, N; Nguyen, HH; Noonan, G; Reiss, TF; Rogers, JD; Seidenberg, BC; Spielberg, S; van Nispen, CH; Xu, X; Zhao, J | 1 |
| Wedekind, CA | 1 |
| Friesen, C; Neustrom, MR | 1 |
| De Lepeleire, I; De Schepper, PJ; Depré, M; Freeman, A; Gertz, B; Holland, S; Shahane, A; Van Hecken, A; Verbesselt, R; Wynants, K | 1 |
| Chuchalin, AG; Gunawardena, KA; Helbling, A; Jasan, J; Langley, SJ; Laurenzi, M; Lee, TH; Leff, JA; Menten, J; O'Neill, SJ; Suskovic, S; van Noord, JA; Villaran, C | 1 |
| Boulet, LP; Efthimiadis, AE; Hargreave, FE; Hendeles, L; Leff, JA; Pizzichini, E; Reiss, TF; Wei, LX; Zhang, J | 1 |
| Barber, BL; Reiss, TF; Santanello, NC; Seidenberg, B; Zhang, J | 1 |
| Bisgaard, H; Loland, L; Oj, JA | 1 |
| Anderson, P | 1 |
| Drazen, JM; Pauwels, R; Wechsler, ME | 1 |
| Bensch, G; Borish, L | 1 |
| Bratton, DL; Lanz, MJ; Miyazawa, N; Silkoff, PE; White, CW | 1 |
| Chervinsky, P; Laviolette, M; Lu, S; Malmstrom, K; Peszek, I; Pujet, JC; Reiss, TF; Zhang, J | 1 |
| Cameron, L; Hamid, Q; Ihaku, D; Martin, J; Molet, S; Suzuki, M | 1 |
| Blau, H; Gil-Ad, I; Nussinovitch, M; Shtaif, B; Tabachnik, E; Varsano, I; Volovitz, B; Weizman, A | 1 |
| Thien, FC | 1 |
| Kuna, P; Kupczyk, M | 1 |
| Hampson, NB | 1 |
| Blake, KV | 1 |
| Bronsky, EA; DeLucca, PT; Edelman, JM; Ghannam, AF; Gormley, GJ; Grossman, J; Kemp, JP; Pearlman, DS; Turpin, JA | 1 |
| Barker, A; Drazen, JM; Finn, D; Gunawardena, D; Haranath, SP; Kips, JC; Pauwels, RA; Wechsler, ME; Westlake, R | 1 |
| Barnes, NC; Kuitert, LM | 1 |
| Baumgartner, RA; Dockhorn, RJ; Leff, JA; Noonan, M; Reiss, TF; Stricker, W; Vandormael, K; Weinland, DE | 1 |
| Berkun, Y; Shalit, M | 1 |
| Becker, A | 2 |
| Price, D | 1 |
| Coutinho, SV; Geller, M; Melo, LR | 1 |
| Hidalgo, R; Martin-Escribano, P; Sotelo, MT; Villena, V | 1 |
| Baskin, S; Gammerman, I; Rapoport, A; Sheftell, F; Walker, B; Weeks, R | 1 |
| Dempsey, OJ; Lipworth, BJ; Mistry, C; Sims, EJ; Wilson, AM | 1 |
| Chapman, KR; D'Urzo, AD | 1 |
| Jarvis, B; Markham, A | 1 |
| Lu, S; Malmstrom, K; Meltzer, EO; Prenner, BM; Reiss, TF; Wei, LX; Weinstein, SF; Wolfe, JD | 1 |
| Stey, C | 1 |
| Geller, M | 1 |
| Coutie, WJ; Dempsey, OJ; Lipworth, BJ; Paterson, MC; Sims, EJ; Wilson, A | 1 |
| Dellaripa, PF; Drazen, J; Roth, ME; Wechsler, ME | 1 |
| Gøransson, LG; Omdal, R | 1 |
| Bisgaard, H; Nielsen, KG | 1 |
| Pregent, E | 1 |
| D'Urzo, AD | 1 |
| Bisgaard, H; Bjermer, L; Bousquet, J; Fabbri, LM; Greening, A; Haahtela, T; Holgate, ST; Leff, JA; Picado, C | 1 |
| Kemp, JP | 2 |
| Hosker, HS; Tuggey, JM | 2 |
| Casper, C; Hani, N; Hartmann, K; Hunzelmann, N; Peters, T; Scharffetter-Kochanek, K; Schneider, LA | 1 |
| Szefler, SJ | 1 |
| Bjermer, L; Holand, B; Sandsund, M; Sue-Chu, M | 1 |
| Finn, AF; Geissler, L; Nguyen, H; Peszek, I; Reicin, A; Seidenberg, BC; Weinstein, SF; White, R | 1 |
| Brestel, EP | 1 |
| Burstein-Stein, J; Grieco, AJ | 1 |
| Holland, S; Knorr, B; Nguyen, HH; Reiss, TF; Rogers, JD | 1 |
| Abraham, WM; Allegra, L; Botvinnikova, Y; Forteza, R; Lauredo, I; Sabater, JR; Scuri, M | 1 |
| Dempsey, OJ; Lipworth, BJ | 1 |
| Dempsey, OJ; Lipworth, BJ; Orr, LC; Sims, EJ; Wilson, AM | 1 |
| Corless, JA; Warburton, CJ | 1 |
| Cohen, GN | 1 |
| Stempel, DA; Stoloff, S | 1 |
| Dempsey, OJ | 1 |
| Mehta, PN | 1 |
| Brehler, R; Kütting, B; Nieschalk, M | 1 |
| Airaghi, L; Lorini, M; Suli, C; Tedeschi, A | 1 |
| Busse, WW; Church, N; Emmett, A; Kerwin, E; Knobil, K; Nelson, HS; Rickard, K | 1 |
| García de Lucas, MD; García-Alegría, J; Peralta-Camisuli, L; Trujillo-Santos, AJ | 1 |
| David-Bajar, K; Yanase, DJ | 1 |
| Christiansen, SC; Mathison, DA; Simon, RA; Stevenson, DD | 1 |
| Bisgaard, H | 3 |
| Belvisi, MG; Birrell, MA; Foster, ML; Hele, DJ; Webber, SE | 1 |
| Lipworth, BJ; Orr, LC; Sims, EJ; Wilson, AM | 1 |
| Knorr, B; Michele, TM; Noonan, G; Reiss, TF; Shapiro, G; Shingo, S; Storms, W; Zhang, J | 1 |
| Heyse, JF; Stine, RA | 1 |
| Anderson, KR; Clark, KW; Gong, H; Linn, WS; Terrell, SL | 1 |
| Donohue, JF | 1 |
| D'Oronzio, L; Dambra, P; Ferrannini, A; Loria, MP; Nettis, E; Tursi, A | 1 |
| Pereiro Alonso, ME; Sala Félix, J; Salas Antón, C | 1 |
| Allen, DJ; Singh, SD | 1 |
| Chan, HK; Chau, KW; Law, AK; Ng, DK | 1 |
| Gu, X; Johnston, L; Simons, FE; Simons, KJ | 1 |
| Ben-Joseph, RH; Price, DB; Zhang, Q | 1 |
| Busse, W; Edwards, L; Galant, S; Goode-Sellers, S; Kalberg, C; Raphael, GD; Rickard, K; Srebro, S | 1 |
| Lipworth, BJ; Wilson, AM | 1 |
| Aziz, I; Kastelik, JA; Morice, AH | 1 |
| Bold, T; Gruer, P; Vilardo, L | 1 |
| Mauskopf, J; McLaughlin, T; Stanford, RH; Stempel, DA; Yazdani, C | 1 |
| Artuso, A; Cerqua, N; Di Rienzo, L | 1 |
| Bayram, NG; Dikensoy, O; Filiz, A | 1 |
| Dempsey, OJ; Lipworth, BJ; Sims, EJ; Wilson, AM | 2 |
| Reiss, TF; Shingo, S; Zhang, J | 1 |
| Weschler, M | 1 |
| Krawiec, ME; Wenzel, SE | 1 |
| García-Marcos, L; Schuster, A | 1 |
| Al-Ahmadi, W; Al-Gazlan, S; Al-Rawithi, S; Alshowaier, IA; Raines, DA; Yusuf, A | 1 |
| Aristizabal, G; Laessig, W; Lee, BW; Leff, JA; Lyttle, B; Menten, J; Perez-Frias, J; Schuster, A; Sekerel, BE; Simons, FE; Teper, AM; Villa, JR | 1 |
| Asero, R; Lorini, M; Tedeschi, A | 1 |
| Anderson, SD; Brannan, JD; Chan, HK; Gomes, K; King, GG; Seale, JP | 1 |
| Mukhopadhyay, A; Stanley, NN | 1 |
| Bouchelouche, K; Hald, T; Horn, T; Larsen, S; Nordling, J | 1 |
| Bouchelouche, K; Bouchelouche, P; Hald, T; Nordling, J | 2 |
| Barnes, N; Edelman, JM; Leff, JA; Reiss, TF; Shingo, S; Wei, LX; Yu, C | 1 |
| Bukstein, D; O'Brien, K | 1 |
| Boza, ML; Kearns, GL; Knorr, B; Larson, P; Nguyen, HH; Reiss, TF; Rogers, JD; Spielberg, S; Villaran, C; Zhang, J | 1 |
| Busse, WW | 1 |
| Bock, S; Faehndrich, S; Luttmann, W; Matthys, H; Nassenstein, C; Virchow, JC | 1 |
| Guerra, J; Knorr, B; Matz, J; Noonan, G; Reiss, TF; White, R; Williams, B | 1 |
| Spector, SL | 1 |
| Fernández-Ovide, E; González-Quintela, A; Nuñez, R; Piñeiro, J; Vidal, C | 1 |
| Angner, R; Knorr, B; Lu, S; Noonan, GP; Reiss, TF; Williams, B | 1 |
| Green, RH; Pavord, ID | 1 |
| Barnes, PJ; Campbell, D; Robinson, DS | 1 |
| Liebke, C; Niggemann, B; Sommerfeld, C; Wahn, U | 1 |
| Canalías, J; Jolis, R; Sabadell, C | 1 |
| Chan, HH; Leung, TF; Pei, AY | 1 |
| Skoner, D | 1 |
| Louis, R | 1 |
| Boone, R; Emmett, A; Fish, JE; Israel, E; Murray, JJ; Rickard, KA; Yancey, SW | 1 |
| Murray, JA; Pardi, DS; Schwartz, DA | 1 |
| Wergowske, GL | 1 |
| Bisgaard, H; Bratton, DL; Franchi, LM; Knorr, B; LeSouef, P; Michele, TM; Nguyen, HH; Reiss, TF; Santanello, N; Vermeulen, JH | 1 |
| Schubert, MS | 1 |
| Calhoun, WJ; Dorinsky, P; Emmett, A; Kalberg, C; Nathan, RA; Nelson, HS; Pepsin, PJ; Rickard, KA | 1 |
| Saenghirunvattana, S | 1 |
| Bukstein, DA; Henk, HJ; Luskin, AT | 1 |
| Darby, YC; Parikh, A; Ragab, S; Scadding, GK | 1 |
| Grundmann, T; Töpfner, M | 1 |
| Blonski, J; Cash, R | 1 |
| Ernst, ME; Maynard, ML | 1 |
| Adachi, M; Minoguchi, K | 1 |
| Corrocher, R; Di Lorenzo, G; Pacor, ML | 1 |
| Coutie, WJ; Gardiner, Q; Lipworth, BJ; Orr, LC; Sims, EJ; White, PS; Wilson, AM | 1 |
| Holma, R; Korpela, R; Riutta, A; Salmenperä, P; Vapaatalo, H; Virtanen, I | 1 |
| Morice, AH | 1 |
| Currie, G; Fowler, S; Lipworth, BJ | 1 |
| Mastalerz, L; Nizankowska, E; Sanak, M; Szczeklik, A | 1 |
| Gardiner, Q; Lipworth, BJ; Nassif, R; White, PS; Wilson, AM | 1 |
| Białoruska, B; Cichocka-Jarosz, E; Głodzik, I; Lis, G; Szczerbiński, T | 1 |
| Amrani, Y; Hoffman, R; Moore, PE; Panettieri, RA; Shore, SA | 1 |
| Capriles, E; Pérez, C; Sánchez-Borges, M | 1 |
| González-Crespo, F; Jiménez-Alonso, J; Sabio, JM | 1 |
| Kägi, MK | 1 |
| Dueñas-Meza, E; Kosa, L; Leff, JA; Maspero, JF; Pinacho Daza, C; Volovitz, B; Vrijens, F | 1 |
| Hayden, ML | 1 |
| Bobrowska, M; Grzelewski, T; Jerzyńska, J; Kuna, P; Majak, J; Majak, P; Stelmach, I | 1 |
| Alonso, E; de Sousa, AV; Ferreira, MB; Michelena, T; Palma-Carlos, AG; Pereira, E; Pregal, AL; Santos, AS | 1 |
| Chesrown, S; Hendeles, L; Hutson, A; Patel, P; Sherman, J | 1 |
| Biswas, P; Shakir, SA; Wilton, LV | 1 |
| Young, RN | 1 |
| Bousquet, J; Dahlén, B; Dahlén, SE; Holgate, ST; Kowalski, M; Kuna, P; Lumry, WR; Malmström, K; Nizankowska, E; Pauwels, R; Picado, C; Reiss, TF; Shahane, A; Stevenson, DD; Szczeklik, A; Zhang, J | 1 |
| Chi, EY; Chiang, GK; Chu, SJ; Henderson, WR; Jonas, M; Jones, F; Pae, C; Tang, LO; Tsao, SM; Wang, H | 1 |
| Dempsey, OJ; Kennedy, G; Lipworth, BJ | 1 |
| Berisa, F; Cortés, CM; Mateo, ML | 1 |
| Bosch, JA; Orriols, R; Selva, A; Solans, R; Vilardell, M | 1 |
| Koziol, JA; Mathison, DA | 1 |
| Hendeles, L; Segal, R | 1 |
| Davis, EA; Pathak, DS; Stanford, RH | 1 |
| Frew, AJ | 1 |
| Jerzynska, J; Kuna, P; Stelmach, I | 2 |
| Bowers, B; Dorinsky, P; Emmett, A; Kalberg, C; Lieberman, AK; Pearlman, DS; Pepsin, PJ; Rickard, KA; White, MV | 1 |
| Muijsers, RB; Noble, S | 2 |
| Adachi, M; Kihara, N; Kohno, Y; Minoguchi, H; Minoguchi, K; Sano, Y; Yasuhara, H | 1 |
| Meyer, JW; O'Donnell, JC; Stempel, DA | 1 |
| Wiebicke, W | 1 |
| Arshad, H; Holgate, ST; Jeffs, JA; Jennison, S; Rorke, S; Sampson, AP | 1 |
| Abbott, CL; Cobb, DB; Fernández, MC; Watson, WA | 1 |
| Ilowite, J | 1 |
| Jackson, CM; Lipworth, BJ | 2 |
| Aukrust, P; Frøland, SS; Hammer, HB | 1 |
| Wilson, AM | 1 |
| Janson, S; Lazarus, SC | 1 |
| Meltzer, EO | 1 |
| Fregonese, L; Rossi, GA; Sabatini, F; Silvestri, M | 1 |
| Eggleston, PA; Kesavan, J; Nowak-Wegrzyn, A; Phipatanakul, W; Schuberth, K; Van Natta, M; Wood, RA | 1 |
| Dadas, E; Jung, A; Kalicki, B; Straz-Zebrowska, E; Zuber, J | 1 |
| Górski, P; Grzelewski, T; Jerzyńska, J; Kuna, P; Majak, P; Stelmach, I; Stelmach, W | 2 |
| Martínez González, A; Mendia, JL; Naberan Toña, KX | 1 |
| Capra, V; Nicosia, S; Panigalli, T; Ravasi, S; Rovati, GE | 1 |
| Bodini, A; Boner, AL; Costella, S; Del Giudice, MM; Peroni, DG; Piacentini, GL; Vicentini, L | 1 |
| Coutie, WJ; Lipworth, BJ; Orr, LC; Sims, EJ; Wilson, AM | 1 |
| Edwards, L; Friedman, BF; Goode-Sellers, S; Kalberg, C; Lockey, RF; Meltzer, EO; Rickard, K; Srebro, S | 1 |
| Addis, A; Buzzetti, R; D'Amico, R | 1 |
| Cohen, P; Guillevin, L; Guilpain, P; Kambouchner, M; Lagarde, P; Pellegrin, JL; Viallard, JF | 1 |
| Noonan, G; Reiss, TF; Yu, C; Zhang, J | 1 |
| Parra Arrondo, A; Pérez de Llano, LA; Veres Racamonde, A | 1 |
| Lötvall, J; Praks, L; Pullerits, T; Ristioja, V | 1 |
| Virchow, JC | 1 |
| Lu, S; Malice, MP; Nayak, AS; Philip, G; Reiss, TF | 1 |
| Hampel, FC; LaForce, CF; Malice, MP; Malmstrom, K; Philip, G; Ratner, PH; Reiss, TF; Weinstein, SF | 1 |
| Fowler, SJ; Hall, IP; Lipworth, BJ; Wheatley, AP; Wilson, AM | 1 |
| Baatjes, AJ; Braccioni, F; Denburg, JA; Dorman, SC; Foley, R; Gauvreau, GM; Inman, MD; O'byrne, PM; Parameswaran, K | 1 |
| Edell, D; Khoshoo, V; Ross, G | 1 |
| Boner, AL; De Gasperi, W; Loiacono, A; Micciolo, R; Peroni, DG; Piacentini, GL; Pietrobelli, A; Sabbion, A | 1 |
| Droste, G; Köhler, D; Lauter, H; Riffelmann, FW | 2 |
| Fujimura, M; Igarashi, T; Nakajima, S; Takagi, K; Takahashi, K; Taniguchi, H; Tohda, Y; Yasuhara, H | 1 |
| Bjermer, L; Sandsund, M; Steinshamn, S; Sue-Chu, M | 2 |
| Gal, AA; Morris, RJ; Pine, JR; Spraker, MK | 1 |
| Erbagci, Z | 1 |
| Cmiel, A; Gawlewicz-Mroczka, A; Mastalerz, L; Nizankowska, E; Szczeklik, A | 1 |
| Baraldi, E; Ghiro, L; Pasquale, MF; Piovan, V; Rampon, O; Zanconato, S | 1 |
| Becler, K; Håkansson, L; Rak, S | 1 |
| Fanelli, M; Ferrannini, A; Nettis, E; Pannofino, A; Tursi, A | 1 |
| Fee, WH | 1 |
| Borker, R; Dorinsky, P; Emmett, A; Rickard, K; Sheth, K | 1 |
| Delorme, N; Drouet, M; Thibaudeau, A; Verret, JL | 1 |
| Inman, MD; Leigh, R; O'Byrne, PM; Rerecich, T; Vethanayagam, D; Watson, RM; Yoshida, M | 1 |
| Abraham, WM; Sabater, JR; Wanner, A | 1 |
| Eschenhagen, T; Mühlhäuser, U; Münzel, F | 1 |
| Böhme, S; Jörres, RA; Kanniess, F; Magnussen, H; Richter, K | 1 |
| Christensen, G; Finsnes, F; Lyberg, T; Skjønsberg, OH | 1 |
| Janicki, S; Jörres, RA; Kanniess, F; Magnussen, H; Richter, K; Schleiss, MB | 1 |
| Camargo, CA; Green, SA; Malice, MP; Reiss, TF; Smithline, HA | 1 |
| Bates, CE; Currie, GP; Haggart, K; Lee, DK; Lipworth, BJ | 1 |
| Gewirtz, AT; Kucharzik, T; Madara, JL; Merlin, D; Williams, IR | 1 |
| Korenblat, PE; Strunk, RC | 1 |
| Bird, SR; Chervinsky, PS; Edelman, JM; Friedman, B; Ghannam, AF; Israel, E; Skalky, CS; Van Bavel, J | 1 |
| Akveld, M; Burke, CM; O'Sullivan, S; Poulter, LW | 1 |
| Aralla, R; Bodini, A; Boner, AL; Loiacono, A; Peroni, DG; Piacentini, GL; Ress, M | 1 |
| Bez, C; Eickmeier, O; Schmitt-Grohé, S; Schubert, R; Zielen, S | 1 |
| Nishikibe, M; Suzuki, J | 1 |
| Campbell, H; Eidelman, DH; Eum, SY; Hamid, Q; Maghni, K; Martin, JG | 1 |
| Bonnans, C; Bousquet, J; Chanez, P; Mainprice, B; Urbach, V | 1 |
| Bailey, B; Carrière, B; Chabot, G; Lebel, D | 1 |
| Berger, ML; Edelman, JM; Markson, LE; Narayanan, S | 1 |
| Kulus, M | 1 |
| Graff, GR; Smith, AL; Weber, A; Wessler-Starman, D | 1 |
| Armstrong, GR; Attwood, SE; Bronder, CS; Lewis, CJ; Morris, CD; Whittam, J | 1 |
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| Bagood, MD; Caryotakis, SE; Isseroff, RR; Nguyen, AV; Shen, H; Smith, G; Soulika, AM; Wang, M; Yee, S | 1 |
| Goto, M; Hatakeyama, S; Kosaki, R; Murashima, A; Nagase, S; Ogura, J; Takahashi, K; Tsutsumi, S; Watanabe, N; Yakuwa, N; Yamaguchi, H; Yamamoto, A; Yamane, R | 1 |
| Giallongo, A; Indolfi, C; Leonardi, S; Licari, A; Manti, S; Marseglia, GL; Miraglia Del Giudice, M; Papale, M; Parisi, GF; Salpietro, C | 1 |
| Cummings, TH; Hardin, JW; Magagnoli, J; Sutton, SS | 1 |
| Fazel, S; Forton, J; Herttua, K; Luciano, S; Paljarvi, T | 1 |
| Alba-Muñoz, J; Calvín-Lamas, M; Parra-Arrondo, A; Pérez-Quintero, O; Rodríguez, RL; Veleiro-Pérez, B | 1 |
| Chen, Y; Shi, H; Wang, X; Zou, P | 1 |
| Attalla, M; Kaminsky, E; Taavola, H; Watson, S; Yue, QY | 1 |
| Enrique, N; Garofalo, FM; Gavernet, L; Llanos, MA; Martín, P; Sbaraglini, ML; Talevi, A | 1 |
| Conrad, LA; Nandalike, K; Rani, S; Rastogi, D | 1 |
| Jun, X; Jun, Z; Ping, Z; Yan, W | 1 |
| Dolatshahi, K; Hakamifard, A; Khorvash, F; Nasirharandi, S; Nasirian, M; Soltani, R | 1 |
| Al-Mudhafar, DH; Al-Nafakh, RT; Alnfakh, ZA; Hadi, NR; Jasim, AE | 1 |
| Abdallah, DM; Ahmed, KA; El-Abhar, HS; Fleifel, AM; Soubh, AA | 1 |
| Campbell, EH; Hwang, AS; Sartori-Valinotti, JC | 1 |
| Choi, JH; Choi, YS; Choi, YW; Ho, MJ; Joung, MY; Kang, MJ; Kim, MS; Lee, S; Park, HJ; Park, JS; Seo, JH; Song, WH | 1 |
| Alipour, S; Dastgheib, L; Fazelzadeh Haghighi, N; Ranjbar, S; Saki, N | 1 |
| Huang, Z; Jian, X; Li, J; Li, K; Liang, B | 1 |
| Azab, AN; Betesh-Abay, B; Biton, L; Kaplanski, J; Nassar, A; Rostevanov, IS; Rubin, E; Uzzan, S | 1 |
| Cho, YJ; Choi, BW; Jung, JW; Kim, MH; Kwon, JW; Nam, YH; Park, CS; Park, HJ; Park, JS; Shin, YS; Sohn, KH | 1 |
| Chen, Q; Lai, K; Li, H; Liu, B; Luo, W; Peng, W; Tang, J; Yi, F; Zhan, C; Zhou, J | 1 |
| Justino, GC; Marques, CF; Marques, MM | 1 |
| Alfonso Martin, C; Alkhader, LF; Batalle, D; Cai, V; Dimitrova, R; Edwards, AD; Fernandes, C; Goikolea-Vives, A; Gressens, P; Hammond, B; Kislitsyna, E; Sewell, AL; Skaland, A; Stolp, HB; Thornton, C; Yates, AG; Zhang, J | 1 |
| Caliendo, G; Camerlingo, R; Cerqua, I; Cirino, G; Costa, SKP; Feitosa, KB; Fiorino, F; Frecentese, F; Granato, E; Muscara, M; Pavese, R; Petti, A; Rea, G; Roviezzo, F; Santagada, V; Severino, B; Soares, AG | 1 |
| Chung, H; Gerke, AK; Hanken, K; Lund, BC | 1 |
| Chen, Y; Wei, S; Zhang, J | 1 |
| Justino, GC; Marques, CF; Pinheiro, PF | 1 |
| Larsson, H; Liu, B; Ludvigsson, JF; Lundholm, C; Pedersen, NL; Sjölander, A; Svenningsson, P; Wallin, J; Williams, DM; Wirdefeldt, K | 1 |
| Can, D; Erdem, SB; Nacaroglu, HT | 1 |
| Bacelar, ACZ; Barreto, AJM; Biguetti, CC; Chaves-Neto, AH; da Silva, RBP; Duarte, MAH; Ervolino, E; Fakhouri, WD; Matsumoto, MA; Ribeiro, KHC; Roseno, ACB | 1 |
| McCarthy, MW | 1 |
| Bønnelykke, K; Eklöf, J; Jordan, A; Meteran, H; Sivapalan, P; Stæhr Jensen, JU; Toennesen, LL; Ulrik, CS | 1 |
| Chen, F; Chu, F; Liang, L | 1 |
| Gales, C; Nechifor, M; Rusu-Zota, G; Stoica, B | 1 |
| Bijandi, M; Erfan Talab Evini, P; Gachkar, L; Mostafazadeh, B; Rahimi, M; Ramezani, M; Shadnia, S | 1 |
| Bloom, CI; Chan, EWY; Fung, LWY; Lo, CWH; Pathadka, S; Qin, SX; Wong, ICK; Yan, VKC; Yiu, HHE | 1 |
| Li, S; Wei, Z | 1 |
184 review(s) available for phenyl acetate and montelukast
| Article | Year |
|---|---|
The role of antileukotrienes in asthma management.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Chromones; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 1998 |
Pharmacology of leukotriene receptor antagonists.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Bronchoconstriction; Cyclopropanes; Dicarboxylic Acids; Disease Models, Animal; Humans; In Vitro Techniques; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 1998 |
Chemistry and structure--activity relationships of leukotriene receptor antagonists.
Topics: Acetates; Anti-Asthmatic Agents; Biological Availability; Chromones; Cyclopropanes; Indoles; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Phenylcarbamates; Quinolines; SRS-A; Structure-Activity Relationship; Sulfides; Sulfonamides; Tosyl Compounds | 1998 |
Montelukast.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Drug Tolerance; Humans; Quinolines; Sulfides | 1998 |
Leukotriene antagonism in asthma and rhinitis.
Topics: Acetates; Asthma; Bronchi; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotriene D4; Lipoxygenase Inhibitors; Membrane Proteins; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Rhinitis; Sinusitis; Sulfides; Sulfonamides; Tosyl Compounds | 1998 |
Leukotriene-receptor antagonists.
Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Drug Administration Schedule; Humans; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Perennial; Sulfides; Sulfonamides; Tosyl Compounds | 1999 |
Montelukast and zafirlukast in asthma.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Asthma, Exercise-Induced; Child; Cyclopropanes; Humans; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Randomized Controlled Trials as Topic; Sulfides; Sulfonamides; Tosyl Compounds | 1998 |
[Leukotriene antagonists].
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 1999 |
Role of leukotrienes and leukotriene receptor antagonists in asthma.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 1999 |
Leukotriene modifiers in chronic urticaria.
Topics: Acetates; Adolescent; Adult; Child; Chronic Disease; Cyclopropanes; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Female; Follow-Up Studies; Histamine H1 Antagonists; Humans; Indoles; Leukotriene Antagonists; Male; Middle Aged; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome; Urticaria | 1999 |
[The role of leukotrienes in inflammation and leukotriene inhibitors].
Topics: Acetates; Arachidonate 5-Lipoxygenase; Asthma; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 1999 |
Montelukast: data from clinical trials in the management of asthma.
Topics: Acetates; Adult; Animals; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Quinolines; Sulfides | 1999 |
Clinical evidence with montelukast in the management of chronic childhood asthma.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Child; Chronic Disease; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2000 |
Tolerability of montelukast.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Child; Churg-Strauss Syndrome; Controlled Clinical Trials as Topic; Cyclopropanes; Humans; Leukotriene Antagonists; Product Surveillance, Postmarketing; Quinolines; Sulfides | 2000 |
Leukotriene-receptor antagonists. Role in asthma management.
Topics: Acetates; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Bronchial Spasm; Chronic Disease; Cyclopropanes; Double-Blind Method; Humans; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Randomized Controlled Trials as Topic; Respiratory Therapy; Sulfides; Sulfonamides; Time Factors; Tosyl Compounds | 2000 |
Montelukast: a review of its therapeutic potential in persistent asthma.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Quinolines; Sulfides | 2000 |
[Leukotriene antagonists--do they have a value?].
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome | 2000 |
Asthma: the new advances.
Topics: Acetates; Administration, Inhalation; Adult; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Glucocorticoids; Humans; Leukotriene Antagonists; Pulmonary Ventilation; Quinolines; Risk Factors; Severity of Illness Index; Sulfides; Theophylline | 2000 |
Montelukast adult (10-mg film-coated tablet) and pediatric (5-mg chewable tablet) dose selections.
Topics: Acetates; Adult; Asthma; Child; Child, Preschool; Cyclopropanes; Dose-Response Relationship, Drug; Humans; Leukotriene Antagonists; Quinolines; Sulfides; Tablets | 2000 |
Leukotriene receptor antagonists for non-cystic fibrosis bronchiectasis.
Topics: Acetates; Bronchiectasis; Clinical Trials as Topic; Cyclopropanes; Humans; Indoles; Leukotriene Antagonists; Phenylcarbamates; Placebos; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 2000 |
Leukotriene receptor antagonist therapy.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Asthma, Exercise-Induced; Chronic Disease; Cyclopropanes; Humans; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 2000 |
Leukotriene modifiers in pediatric asthma management.
Topics: Acetates; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Membrane Proteins; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds | 2001 |
Clinical safety and tolerability of montelukast, a leukotriene receptor antagonist, in controlled clinical trials in patients aged > or = 6 years.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Child; Chronic Disease; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Multicenter Studies as Topic; Quinolines; Randomized Controlled Trials as Topic; Sulfides; Treatment Outcome | 2001 |
[Treatment of asthma with antileukotrienes and Churg-Strauss syndrome].
Topics: Acetates; Adult; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2001 |
Leukotriene inhibitors and non-steroidal therapies in the treatment of asthma.
Topics: Acetates; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Asthma; Bronchoconstriction; Child; Clinical Trials as Topic; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Phenylcarbamates; Phosphodiesterase Inhibitors; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome | 2001 |
Antileukotrienes in asthma: present situation.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Chromones; Clinical Trials as Topic; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 2001 |
Analysis of montelukast in mild persistent asthmatic patients with near-normal lung function.
Topics: Acetates; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Analysis of Variance; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Eosinophils; Female; Forced Expiratory Volume; Humans; Leukocyte Count; Male; Middle Aged; Quinolines; Randomized Controlled Trials as Topic; Severity of Illness Index; Sulfides; Treatment Outcome | 2001 |
Use of oral montelukast in the treatment of asthma.
Topics: Acetates; Administration, Oral; Adult; Anti-Asthmatic Agents; Asthma; Bronchoconstriction; Child; Clinical Trials as Topic; Cyclopropanes; Drug Interactions; Exercise; Humans; Inflammation Mediators; Quinolines; Sulfides | 2001 |
[Churg-Strauss syndrome associated with montelukast therapy].
Topics: Acetates; Adult; Anti-Asthmatic Agents; Churg-Strauss Syndrome; Cyclopropanes; Female; Humans; Quinolines; Sulfides | 2001 |
Montelukast in 2- to 5-year-old children with asthma.
Topics: Acetates; Administration, Oral; Asthma; Child, Preschool; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2001 |
Leukotriene receptor antagonists in the treatment of allergic rhinitis.
Topics: Acetates; Adolescent; Adult; Aged; Cyclopropanes; Humans; Indoles; Leukotriene Antagonists; Middle Aged; Phenylcarbamates; Quinolines; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Perennial; Sulfides; Sulfonamides; Tosyl Compounds; United States | 2001 |
[Leukotriene modifiers].
Topics: Acetates; Asthma; Chromones; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Membrane Proteins; Phenylcarbamates; Practice Guidelines as Topic; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds | 2001 |
Leukotriene receptor antagonists--a novel therapeutic approach in atopic dermatitis?
Topics: Acetates; Cyclopropanes; Dermatitis, Atopic; Humans; Leukotriene Antagonists; Leukotrienes; Quinolines; Sulfides; Urticaria | 2001 |
Leukotriene modifiers. Expanded role may be on horizon.
Topics: Acetates; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Cyclopropanes; Drug Interactions; Drug Therapy, Combination; Forced Expiratory Volume; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Patient Compliance; Phenylcarbamates; Quinolines; Safety; Steroids; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome | 2000 |
Discovery of montelukast: a once-a-day oral antagonist of leukotriene D4 for the treatment of chronic asthma.
Topics: Acetates; Administration, Oral; Animals; Asthma; Chromones; Chronic Disease; Cyclopropanes; Humans; Leukotriene Antagonists; Leukotriene D4; Lung; Quinolines; Sulfides | 2001 |
Montelukast: a review of its therapeutic potential in asthma in children 2 to 14 years of age.
Topics: Acetates; Adolescent; Asthma; Bronchoconstriction; Child; Child, Preschool; Cyclopropanes; Humans; Leukotriene Antagonists; Membrane Proteins; Quinolines; Randomized Controlled Trials as Topic; Receptors, Leukotriene; Sulfides; Treatment Outcome | 2002 |
Are antihistamines useful in managing asthma?
Topics: Acetates; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchospirometry; Cetirizine; Cyclopropanes; Drug Therapy, Combination; Histamine H1 Antagonists; Humans; Loratadine; Mannitol; Quinolines; Rhinitis; Sulfides; Terfenadine | 2002 |
Where do leukotriene modifiers fit in asthma management?
Topics: Acetates; Asthma; Child; Churg-Strauss Syndrome; Cyclopropanes; Forced Expiratory Volume; Humans; Indoles; Leukotriene Antagonists; Leukotrienes; Phenylcarbamates; Quinolines; Severity of Illness Index; Sulfides; Sulfonamides; Tosyl Compounds | 2002 |
Clinical evidence for antileukotriene therapy in the management of allergic rhinitis.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Cyclopropanes; Histamine H1 Antagonists; Humans; Leukotriene Antagonists; Loratadine; Middle Aged; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides | 2002 |
[Reflections on antileukotrienes].
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 2002 |
Churg-Strauss syndrome in two patients receiving montelukast.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Churg-Strauss Syndrome; Cyclophosphamide; Cyclopropanes; Drug Therapy, Combination; Glucocorticoids; Humans; Immunosuppressive Agents; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Sulfides | 2002 |
Effect of interventions during acute respiratory syncytial virus bronchiolitis on subsequent long term respiratory morbidity.
Topics: Acetates; Acute Disease; Adrenal Cortex Hormones; Antiviral Agents; Bronchiolitis, Viral; Cromolyn Sodium; Cyclopropanes; Humans; Infant; Infant Welfare; Infant, Newborn; Leukotriene Antagonists; Morbidity; Prospective Studies; Quinolines; Respiratory Syncytial Virus Infections; Retrospective Studies; Sulfides | 2002 |
[Cold-induced urticaria].
Topics: Acetates; Adrenal Cortex Hormones; Aminophylline; Cold Temperature; Cyclopropanes; Doxepin; Drug Therapy, Combination; Female; Genes, Dominant; Histamine H1 Antagonists; Humans; Hypotension; Male; Quinolines; Stanozolol; Sulfides; Terbutaline; Urticaria | 2002 |
[Leukotriene antagonist drugs].
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 2002 |
A case of montelukast-induced hepatotoxicity.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Chemical and Drug Induced Liver Injury; Cyclopropanes; Humans; Leukotriene Antagonists; Liver; Liver Function Tests; Male; Quinolines; Sulfides | 2003 |
New treatments for asthma: the role of leukotriene modifier agents.
Topics: Acetates; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Asthma, Exercise-Induced; Cyclopropanes; Drug Evaluation; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome | 1999 |
The role of leukotrienes in nasal allergy.
Topics: Acetates; Anti-Allergic Agents; Collagen; Cyclopropanes; Eosinophils; Goblet Cells; Humans; Immunoglobulin E; Interleukin-4; Leukotriene Antagonists; Leukotrienes; Loratadine; Mucociliary Clearance; Nasal Mucosa; Nasal Polyps; Quinolines; Rhinitis, Allergic, Perennial; Sulfides | 2003 |
Seasonal allergic rhinitis.
Topics: Acetates; Administration, Intranasal; Administration, Oral; Cyclopropanes; Histamine H1 Antagonists; Humans; Leukotriene Antagonists; Nasal Decongestants; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides | 2003 |
Atopic diseases of childhood.
Topics: Acetates; Adrenergic beta-Agonists; Animals; Asthma; Child; Cyclopropanes; Dermatitis, Atopic; Environmental Exposure; Feces; Genetic Predisposition to Disease; Hepatitis A Virus Cellular Receptor 1; Hepatitis A Virus Cellular Receptor 2; Humans; Hypersensitivity, Immediate; Immunosuppressive Agents; Leukotriene Antagonists; Membrane Proteins; Mice; Quinolines; Receptors, Virus; Skin; Sulfides; T-Lymphocytes; Tacrolimus | 2003 |
[Anti-leukotrienes in allergic diseases in children].
Topics: Acetates; Asthma; Child; Cyclopropanes; Humans; Hydroxyurea; Leukotriene Antagonists; Leukotrienes; Membrane Proteins; Quinolines; Receptors, Leukotriene; Sulfides | 2003 |
Recent advances in the management of asthma using leukotriene modifiers.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Asthma; Child; Child, Preschool; Chromones; Controlled Clinical Trials as Topic; Cyclopropanes; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydroxyurea; Leukotriene Antagonists; Male; Middle Aged; Peak Expiratory Flow Rate; Quinolines; Respiratory Function Tests; Severity of Illness Index; Sulfides; Treatment Outcome | 2003 |
Spotlight on montelukast in asthma in children 2 to 14 years of age.
Topics: Acetates; Administration, Oral; Adolescent; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Drug Administration Schedule; Drug Therapy, Combination; Humans; Quinolines; Randomized Controlled Trials as Topic; Sulfides | 2002 |
Advances in adult and pediatric asthma.
Topics: Acetates; ADAM Proteins; Administration, Inhalation; Adrenal Cortex Hormones; Adult; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Female; Humans; Male; Metalloendopeptidases; Osteoporosis; Pregnancy; Pregnancy Complications; Quinolines; Respiratory System; Sulfides; United States | 2004 |
A review of montelukast in the treatment of asthma and allergic rhinitis.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Leukotriene Antagonists; Membrane Proteins; Quinolines; Randomized Controlled Trials as Topic; Receptors, Leukotriene; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sulfides | 2004 |
Problems in the management of asthma in young children--a potential role for montelukast.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Humans; Infant; Patient Compliance; Quality of Life; Quinolines; Sulfides; Treatment Outcome | 2004 |
Asthma and other wheezing disorders in infants and children.
Topics: Acetates; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cromolyn Sodium; Cyclopropanes; Drug Therapy, Combination; Humans; Infant; Ipratropium; Nebulizers and Vaporizers; Nedocromil; Quinolines; Respiratory Sounds; Sulfides; Theophylline | 2004 |
[Mechanisms of action of cysteinyl leukotriene receptor antagonist and progresses in relevant studies in children with asthma].
Topics: Acetates; Animals; Asthma; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Receptors, Leukotriene; Sulfides | 2005 |
Antiinflammatory therapies for cystic fibrosis: past, present, and future.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adult; Anti-Inflammatory Agents; Azithromycin; Child; Clinical Trials as Topic; Cyclopropanes; Cystic Fibrosis; Deoxyribonuclease I; Dietary Supplements; Humans; Methotrexate; Pentoxifylline; Quinolines; Sulfides | 2005 |
Inhaled salmeterol/fluticasone propionate: a review of its use in asthma.
Topics: Acetates; Administration, Inhalation; Albuterol; Androstadienes; Asthma; Asthma, Exercise-Induced; Bronchodilator Agents; Budesonide; Clinical Trials as Topic; Cyclopropanes; Drug Combinations; Economics, Pharmaceutical; Ethanolamines; Fluticasone; Fluticasone-Salmeterol Drug Combination; Formoterol Fumarate; Humans; Quinolines; Salmeterol Xinafoate; Sulfides; Therapeutic Equivalency | 2005 |
Childhood asthma. Balancing efficacy and adherence for optimum management.
Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Humans; Indoles; Infant; Leukotriene Antagonists; Phenylcarbamates; Practice Guidelines as Topic; Quinolines; Severity of Illness Index; Sulfides; Sulfonamides; Tosyl Compounds | 2005 |
Leukotriene receptor antagonists--an update.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Asthma; Child; Child, Preschool; Cyclopropanes; Delayed-Action Preparations; Humans; Indoles; Infant; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome | 2005 |
Treatment of asthma with antileukotrienes: first line or last resort therapy?
Topics: Acetates; Animals; Asthma; Clinical Trials as Topic; Cyclopropanes; Humans; Hydroxyurea; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Lipoxygenase Inhibitors; Membrane Proteins; Quinolines; Receptors, Leukotriene; Respiratory System; Rhinitis; Sulfides | 2006 |
Montelukast (Singulair) for perennial allergic rhinitis.
Topics: Acetates; Adult; Cross-Over Studies; Cyclopropanes; Female; Follow-Up Studies; Humans; Leukotriene Antagonists; Quinolines; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Perennial; Risk Assessment; Severity of Illness Index; Sulfides; Treatment Outcome | 2006 |
Leukotriene receptor antagonist for prolonged non-specific cough in children.
Topics: Acetates; Child; Cough; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2006 |
Montelukast treatment of urticaria.
Topics: Acetates; Clinical Trials as Topic; Cyclopropanes; Drug Therapy, Combination; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Quinolines; Sulfides; Urticaria | 2006 |
Montelukast in pediatric asthma management.
Topics: Acetates; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Asthma; Bronchial Diseases; Child; Constriction, Pathologic; Cyclopropanes; Humans; Infant; Leukotriene Antagonists; Practice Guidelines as Topic; Quinolines; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Seasonal; Sulfides | 2006 |
Evolving role of leukotrienes in the pathogenesis of viral infections, including otitis media.
Topics: Acetates; Cyclopropanes; Humans; Infant; Leukotriene Antagonists; Leukotrienes; Otitis Media; Quinolines; Sulfides; Virus Diseases | 2006 |
Managing asthma in the 21st century: role of pharmacogenetics.
Topics: Acetates; Adrenergic beta-Agonists; Anti-Asthmatic Agents; Asthma; Beclomethasone; Cyclopropanes; Genotype; Humans; Pharmacogenetics; Polymorphism, Single Nucleotide; Quinolines; Receptors, Adrenergic, beta; Sulfides | 2006 |
Single-inhaler combination therapy for asthma: a review of cost effectiveness.
Topics: Acetates; Androstadienes; Anti-Asthmatic Agents; Asthma; Budesonide; Clinical Trials as Topic; Cost-Benefit Analysis; Cyclopropanes; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ethanolamines; Fluticasone; Formoterol Fumarate; Humans; Nebulizers and Vaporizers; Quinolines; Sulfides | 2006 |
Montelukast in allergic rhinitis: a systematic review and meta-analysis.
Topics: Acetates; Adrenal Cortex Hormones; Clinical Trials as Topic; Cyclopropanes; Drug Therapy, Combination; Histamine H1 Antagonists; Humans; Leukotriene Antagonists; Quality of Life; Quinolines; Rhinitis, Allergic, Perennial; Sulfides; Surveys and Questionnaires; Treatment Outcome | 2006 |
Cysteinyl-leukotriene receptor antagonists: present situation and future opportunities.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Leukotriene Antagonists; Membrane Proteins; Quinolines; Receptors, Leukotriene; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sulfides; Treatment Outcome | 2006 |
Leukotriene inhibitors in the treatment of allergy and asthma.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Asthma, Exercise-Induced; Cyclopropanes; Dermatitis, Atopic; Humans; Hydroxyurea; Hypersensitivity; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sulfides; Sulfonamides; Tosyl Compounds | 2007 |
Eosinophilic esophagitis: an update.
Topics: Acetates; Adrenal Cortex Hormones; Allergens; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Catheterization; Cyclopropanes; Diet; Eosinophilia; Esophagitis; Food Hypersensitivity; Humans; Leukotriene Antagonists; Prognosis; Quinolines; Sulfides | 2007 |
[Antileukotrienes and Churg-Strauss syndrome].
Topics: Acetates; Adult; Anti-Asthmatic Agents; Antibodies, Antineutrophil Cytoplasmic; Asthma; Chromones; Churg-Strauss Syndrome; Cohort Studies; Cyclopropanes; Humans; Incidence; Indoles; Leukotriene Antagonists; Leukotrienes; Phenylcarbamates; Quinolines; Retrospective Studies; Sulfides; Sulfonamides; Tosyl Compounds | 2007 |
Montelukast in the treatment of allergic rhinitis: an evidence-based review.
Topics: Acetates; Asthma; Child; Cyclopropanes; Drug Administration Schedule; Evidence-Based Medicine; Humans; Leukotriene Antagonists; Placebo Effect; Quinolines; Receptors, Leukotriene; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sulfides | 2007 |
Leukotriene synthesis inhibitors versus antagonists: the pros and cons.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Arachidonate 5-Lipoxygenase; Asthma; Chromones; Cyclopropanes; Humans; Hypersensitivity; Indoles; Inflammation Mediators; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds | 2007 |
Update on montelukast and its role in the treatment of asthma, allergic rhinitis and exercise-induced bronchoconstriction.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Asthma, Exercise-Induced; Bronchoconstriction; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sulfides | 2007 |
Desloratadine for chronic idiopathic urticaria: a review of clinical efficacy.
Topics: Acetates; Adolescent; Adult; Child; Chronic Disease; Cyclopropanes; Drug Therapy, Combination; Histamine H1 Antagonists, Non-Sedating; Humans; Infant; Leukotriene Antagonists; Loratadine; Quality of Life; Quinolines; Sulfides; Urticaria | 2007 |
[Adverse effects of leukotriene-antagonists].
Topics: Acetates; Anaphylaxis; Chemical and Drug Induced Liver Injury; Chromones; Cyclopropanes; Drug Interactions; Enzyme Inhibitors; Hematologic Diseases; Humans; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung Diseases, Interstitial; Membrane Proteins; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds | 2007 |
[Eosinophilic esophagitis--pathogenesis, clinical presentation and therapeutic management].
Topics: Acetates; Adrenal Cortex Hormones; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bezoars; Catheterization; Cyclopropanes; Deglutition Disorders; Eosinophilia; Eosinophils; Esophagitis; Esophagoscopy; Humans; Leukocyte Count; Quinolines; Sulfides; Th2 Cells | 2007 |
Inhaled corticosteroids or montelukast as the preferred primary long-term treatment for pediatric asthma?
Topics: Acetates; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Androstadienes; Asthma; Bronchodilator Agents; Child; Child, Preschool; Cyclopropanes; Fluticasone; Humans; Infant; Leukotriene Antagonists; Quinolines; Randomized Controlled Trials as Topic; Sulfides; Treatment Outcome | 2008 |
Dyspepsia in childhood and adolescence: insights and treatment considerations.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Acetates; Acupuncture Therapy; Adolescent; Animals; Child; Cognitive Behavioral Therapy; Cyclopropanes; Dyspepsia; Endoscopy, Gastrointestinal; Gastric Emptying; Gastrointestinal Motility; Helicobacter Infections; Helicobacter pylori; Humans; Hypnosis; Imagery, Psychotherapy; Lansoprazole; Leukotriene Antagonists; Phytotherapy; Plant Extracts; Proton Pump Inhibitors; Quinolines; Serotonin; Stomach; Sulfides; Viscera; Zingiber officinale | 2007 |
Churg-Strauss syndrome associated with montelukast therapy.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Drug Eruptions; Female; Humans; Middle Aged; Quinolines; Respiratory Function Tests; Sulfides; Treatment Outcome | 2008 |
Montelukast as add-on therapy to inhaled corticosteroids in the treatment of mild to moderate asthma: a systematic review.
Topics: Acetates; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Albuterol; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Drug Therapy, Combination; Female; Humans; Male; Quinolines; Randomized Controlled Trials as Topic; Salmeterol Xinafoate; Sulfides | 2008 |
Review of recent results of montelukast use as a monotherapy in children with mild asthma.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adolescent; Anti-Asthmatic Agents; Asthma; Asthma, Exercise-Induced; Bronchoconstriction; Child; Child, Preschool; Cyclopropanes; Glucocorticoids; Humans; Hypersensitivity, Immediate; Leukotriene Antagonists; Patient Compliance; Quinolines; Randomized Controlled Trials as Topic; Sulfides | 2008 |
Obstructive sleep disordered breathing in children: beyond adenotonsillectomy.
Topics: Acetates; Adenoidectomy; Child; Child, Preschool; Cyclopropanes; Humans; Leukotriene Antagonists; Orthodontics, Corrective; Quinolines; Sleep Apnea Syndromes; Sulfides; Tonsillectomy | 2008 |
Montelukast and emotional well-being as a marker for depression: results from 3 randomized, double-masked clinical trials.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Depression; Double-Blind Method; Emotions; Female; Humans; Male; Multicenter Studies as Topic; Quality of Life; Quinolines; Randomized Controlled Trials as Topic; Suicide; Sulfides | 2008 |
Montelukast sodium for exercise-induced asthma.
Topics: Acetates; Administration, Oral; Adolescent; Anti-Asthmatic Agents; Asthma, Exercise-Induced; Child; Child, Preschool; Cyclopropanes; Humans; Leukotriene Antagonists; Meta-Analysis as Topic; Molecular Structure; Quinolines; Sulfides | 2008 |
Eosinophilic oesophagitis in adults.
Topics: Acetates; Adrenal Cortex Hormones; Adult; Cyclopropanes; Dilatation; Eosinophils; Esophagitis; Esophagoscopy; Food Hypersensitivity; Humans; Immunologic Factors; Proton Pump Inhibitors; Quinolines; Sulfides | 2009 |
Safety and tolerability of montelukast in placebo-controlled pediatric studies and their open-label extensions.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Humans; Infant; Quinolines; Rhinitis, Allergic, Perennial; Sulfides | 2009 |
Suicidality and montelukast.
Topics: Acetates; Cyclopropanes; Humans; Hypersensitivity; Quinolines; Risk Factors; Suicide; Suicide Prevention; Sulfides | 2009 |
Update on the medical treatment of allergic rhinitis.
Topics: Acetates; Adrenal Cortex Hormones; Allergens; Anti-Inflammatory Agents; Cyclopropanes; Disease Progression; Drug Administration Routes; Histamine Antagonists; Humans; Immunosuppression Therapy; Immunotherapy; Meta-Analysis as Topic; Quinolines; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Severity of Illness Index; Skin Tests; Sulfides | 2009 |
Montelukast in guidelines and beyond.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Leukotriene Antagonists; Practice Guidelines as Topic; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides | 2009 |
Targeting leukotrienes for the treatment of COPD?
Topics: 5-Lipoxygenase-Activating Proteins; Acetates; Arachidonate 5-Lipoxygenase; Bronchoconstriction; Capillary Permeability; Carrier Proteins; CD8-Positive T-Lymphocytes; Cell Movement; Chromones; Cyclopropanes; Eosinophils; Humans; Indoles; Leukotriene Antagonists; Leukotrienes; Membrane Proteins; Neutrophils; Phenylcarbamates; Pulmonary Disease, Chronic Obstructive; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 2009 |
Recurrent wheezing illness in preschool-aged children: assessment and management in primary care practice.
Topics: Acetates; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Asthmatic Agents; Asthma; Causality; Child; Child, Preschool; Comorbidity; Cyclopropanes; Diagnosis, Differential; Europe; Female; Humans; Hypersensitivity; Infant; Infant, Newborn; Male; Predictive Value of Tests; Prednisolone; Primary Health Care; Quinolines; Recurrence; Respiratory Sounds; Risk Assessment; Sulfides; Terminology as Topic; United States | 2009 |
The role of inhaled corticosteroids and montelukast in children with mild-moderate asthma: results of a systematic review with meta-analysis.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Drug Therapy, Combination; Forced Expiratory Volume; Glucocorticoids; Humans; Peak Expiratory Flow Rate; Quinolines; Randomized Controlled Trials as Topic; Sulfides; Treatment Outcome | 2010 |
Human rhinoviruses, allergy, and asthma: a clinical approach.
Topics: Acetates; Adult; Allergens; Antiviral Agents; Asthma; Child; Child, Preschool; Consensus; Cyclopropanes; Disease Susceptibility; Follow-Up Studies; Humans; Infant; Interferons; Picornaviridae Infections; Prevalence; Quinolines; Randomized Controlled Trials as Topic; Recurrence; Respiratory Hypersensitivity; Respiratory Sounds; Rhinovirus; Sulfides; Time Factors | 2009 |
Body mass index and response to asthma therapy: fluticasone propionate/salmeterol versus montelukast.
Topics: Acetates; Adult; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Body Mass Index; Cyclopropanes; Double-Blind Method; Drug Combinations; Female; Fluticasone-Salmeterol Drug Combination; Forced Expiratory Volume; Humans; Male; Middle Aged; Multicenter Studies as Topic; Obesity; Overweight; Quinolines; Randomized Controlled Trials as Topic; Sulfides; Time Factors; Treatment Outcome | 2010 |
Congestion and sleep impairment in allergic rhinitis.
Topics: Acetates; Administration, Intranasal; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Cyclopropanes; Fatigue; Humans; Hypersensitivity; Nasal Obstruction; Quality of Life; Quinolines; Rhinitis; Sleep; Sleep Apnea Syndromes; Sleep Stages; Sulfides | 2010 |
Inter-country variations in anti-asthmatic drug prescriptions for children. Systematic review of studies published during the 2000-2009 period.
Topics: Acetates; Adolescent; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Beclomethasone; Budesonide; Canada; Child; Cromolyn Sodium; Cyclopropanes; Drug Prescriptions; Ethanolamines; Europe; Fluocinolone Acetonide; Fluticasone; Humans; Italy; Prevalence; Quinolines; Salmeterol Xinafoate; Sulfides; United States | 2010 |
The employment of leukotriene antagonists in cutaneous diseases belonging to allergological field.
Topics: Acetates; Animals; Cyclopropanes; Humans; Hypersensitivity; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Skin Diseases; Sulfides; Sulfonamides; Tosyl Compounds | 2010 |
Archimedes. Question 2. Is oral montelukast beneficial in treating acute asthma exacerbations in children?
Topics: Acetates; Acute Disease; Administration, Oral; Anti-Asthmatic Agents; Asthma; Child, Preschool; Cyclopropanes; Evidence-Based Medicine; Female; Humans; Quinolines; Sulfides | 2010 |
Long term treatment with montelukast and levocetirizine combination in persistent allergic rhinitis: review of recent evidence.
Topics: Acetates; Cetirizine; Cyclopropanes; Drug Therapy, Combination; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Quality of Life; Quinolines; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Perennial; Sulfides | 2010 |
Pediatric asthma controller therapy.
Topics: Acetates; Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Adult; Age Factors; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Glucocorticoids; Humans; Practice Guidelines as Topic; Quinolines; Sulfides | 2011 |
Montelukast: more than a cysteinyl leukotriene receptor antagonist?
Topics: Acetates; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Cyclopropanes; Humans; Leukotriene Antagonists; Neutrophils; Pulmonary Disease, Chronic Obstructive; Quinolines; Receptors, Leukotriene; Sulfides | 2010 |
Anti-inflammatory medications for obstructive sleep apnea in children.
Topics: Acetates; Administration, Intranasal; Administration, Oral; Androstadienes; Anti-Inflammatory Agents; Budesonide; Child; Child, Preschool; Cyclopropanes; Fluticasone; Humans; Quinolines; Randomized Controlled Trials as Topic; Sleep Apnea, Obstructive; Sulfides | 2011 |
Association between leukotriene-modifying agents and suicide: what is the evidence?
Topics: Acetates; Adverse Drug Reaction Reporting Systems; Cyclopropanes; Drug Labeling; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Suicide; Sulfides; Sulfonamides; Tosyl Compounds; United States; United States Food and Drug Administration | 2011 |
[Montelukast in the treatment of mild to moderate persistent asthma].
Topics: Acetates; Adrenal Cortex Hormones; Adult; Airway Remodeling; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Child; Cyclopropanes; Cytokines; Drug Therapy, Combination; France; Humans; Inflammation; Leukotriene Antagonists; Leukotrienes; Models, Biological; Practice Guidelines as Topic; Prevalence; Quinolines; Randomized Controlled Trials as Topic; Receptors, Leukotriene; Sulfides | 2011 |
Montelukast for the treatment of asthma in the adult population.
Topics: Acetates; Adult; Animals; Anti-Inflammatory Agents; Asthma; Clinical Trials as Topic; Cyclopropanes; Humans; Quinolines; Randomized Controlled Trials as Topic; Sulfides | 2011 |
[What helps for persistent symptoms of asthma during inhalative steroid therapy?].
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Adult; Albuterol; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Child; Cyclopropanes; Drug Therapy, Combination; Ethanolamines; Formoterol Fumarate; Humans; Hydroxyurea; Leukotriene Antagonists; Quality of Life; Quinolines; Randomized Controlled Trials as Topic; Respiratory Function Tests; Salmeterol Xinafoate; Sulfides; Treatment Failure | 2011 |
Clinical effectiveness of inhaled corticosteroids versus montelukast in children with asthma: prescription patterns and patient adherence as key factors.
Topics: Acetates; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Female; Follow-Up Studies; Hospitalization; Humans; Male; Patient Compliance; Practice Patterns, Physicians'; Quinolines; Risk Factors; Sulfides; Treatment Outcome | 2012 |
Airway obstruction lability helps distinguish levels of disease activity in asthma.
Topics: Acetates; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Anti-Asthmatic Agents; Asthma; Beclomethasone; Circadian Rhythm; Clinical Trials, Phase III as Topic; Cyclopropanes; Drug Administration Schedule; Female; Forced Expiratory Volume; Glucocorticoids; Humans; Leukotriene Antagonists; Male; Middle Aged; Peak Expiratory Flow Rate; Quinolines; Randomized Controlled Trials as Topic; Severity of Illness Index; Sulfides; Treatment Outcome; Young Adult | 2012 |
Update on leukotriene receptor antagonists in preschool children wheezing disorders.
Topics: Acetates; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Child, Preschool; Cyclopropanes; Humans; Leukotriene Antagonists; Practice Guidelines as Topic; Quinolines; Respiratory Sounds; Sulfides | 2012 |
Role of leukotriene antagonists and antihistamines in the treatment of allergic rhinitis.
Topics: Acetates; Cyclopropanes; Histamine Antagonists; Humans; Leukotriene Antagonists; Quinolines; Rhinitis, Allergic; Rhinitis, Allergic, Perennial; Sulfides | 2013 |
[Leukotriene and respiratory syncytial virus].
Topics: Acetates; Asthma; Bronchiolitis, Viral; Cyclopropanes; Cysteine; Humans; Infant; Infant, Newborn; Leukotriene Antagonists; Leukotrienes; Nasopharynx; Quinolines; Respiratory Syncytial Virus Infections; Risk Factors; Sulfides | 2013 |
Cough, asthma, and cysteinyl-leukotrienes.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Antitussive Agents; Asthma; Cough; Cyclopropanes; Cysteine; Glucocorticoids; Humans; Leukotriene Antagonists; Leukotrienes; Quinolines; Sputum; Sulfides | 2013 |
Impact of montelukast on asthma associated with rhinitis, and other triggers and co-morbidities.
Topics: Acetates; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Comorbidity; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Rhinitis; Sulfides | 2014 |
Addition of anti-leukotriene agents to inhaled corticosteroids in children with persistent asthma.
Topics: Acetates; Adolescent; Asthma; Child; Cyclopropanes; Drug Therapy, Combination; Humans; Leukotriene Antagonists; Quinolines; Randomized Controlled Trials as Topic; Sulfides | 2013 |
Systematic review of montelukast's efficacy for preventing post-bronchiolitis wheezing.
Topics: Acetates; Age Factors; Bronchiolitis, Viral; Chi-Square Distribution; Child, Preschool; Cyclopropanes; Humans; Infant; Infant, Newborn; Leukotriene Antagonists; Odds Ratio; Quinolines; Respiratory Sounds; Respiratory Syncytial Virus Infections; Risk Factors; Sulfides; Treatment Outcome | 2014 |
Safety and efficacy of montelukast as adjunctive therapy for treatment of asthma in elderly patients.
Topics: Acetates; Aged; Aged, 80 and over; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Female; Humans; Male; Middle Aged; Quinolines; Sulfides | 2013 |
Pharmacotherapy of chronic spontaneous urticaria.
Topics: Acetates; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal, Humanized; Chronic Disease; Cyclopropanes; Cyclosporine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Histamine H1 Antagonists; Histamine Release; Humans; Omalizumab; Practice Guidelines as Topic; Quinolines; Sulfides; Treatment Outcome; Urticaria | 2013 |
Effectiveness of montelukast in pediatric patients with allergic rhinitis.
Topics: Acetates; Administration, Intranasal; Administration, Oral; Adolescent; Adrenal Cortex Hormones; Child; Child, Preschool; Cyclopropanes; Female; Follow-Up Studies; Humans; Leukotriene Antagonists; Male; Pediatrics; Quinolines; Randomized Controlled Trials as Topic; Rhinitis, Allergic; Rhinitis, Allergic, Perennial; Risk Assessment; Severity of Illness Index; Sulfides; Treatment Outcome | 2013 |
Management of critical asthma syndrome during pregnancy.
Topics: Abortion, Spontaneous; Acetates; Adrenal Cortex Hormones; Animals; Asthma; Bronchodilator Agents; Contraindications; Critical Illness; Cyclopropanes; Epinephrine; Female; Humans; Intensive Care Units; Medication Adherence; Pregnancy; Pregnancy Complications; Quinolines; Sulfides; Syndrome | 2015 |
Is montelukast indicated for treatment of chronic rhinosinusitis with polyposis?
Topics: Acetates; Chronic Disease; Cyclopropanes; Humans; Leukotriene Antagonists; Nasal Polyps; Quinolines; Rhinitis; Sinusitis; Sulfides | 2014 |
Leukotriene receptor antagonists pranlukast and montelukast for treating asthma.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Chromones; Cyclopropanes; Cysteine; Humans; Leukotriene Antagonists; Leukotrienes; Quinolines; Sulfides | 2014 |
Evaluation and treatment of critical asthma syndrome in children.
Topics: Acetates; Animals; Asthma; Caregivers; Child; Critical Illness; Cyclopropanes; Humans; Hyperbaric Oxygenation; Immunoglobulins, Intravenous; Patient Compliance; Patient Education as Topic; Practice Guidelines as Topic; Quinolines; Respiration, Artificial; Sulfides; Syndrome | 2015 |
Eosinophilic oesophagitis: investigations and management.
Topics: Acetates; Administration, Inhalation; Anti-Inflammatory Agents; Biopsy; Budesonide; Cyclopropanes; Deglutition Disorders; Eosinophilic Esophagitis; Esophagoscopy; Feeding Behavior; Female; Glucocorticoids; Humans; Immunologic Factors; Male; Quinolines; Sulfides | 2014 |
A meta-analysis of sublingual allergen immunotherapy and pharmacotherapy in pollen-induced seasonal allergic rhinoconjunctivitis.
Topics: Acetates; Administration, Sublingual; Adolescent; Adrenal Cortex Hormones; Adult; Allergens; Androstadienes; Child; Conjunctivitis, Allergic; Cyclopropanes; Desensitization, Immunologic; Double-Blind Method; Drug Combinations; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Phthalazines; Pollen; Quinolines; Rhinitis, Allergic, Seasonal; Seasons; Sublingual Immunotherapy; Sulfides | 2014 |
Cysteinyl leukotriene receptor-1 antagonists as modulators of innate immune cell function.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetates; Anti-Asthmatic Agents; Arachidonate 5-Lipoxygenase; Asthma; Chromones; Cyclopropanes; Gene Expression Regulation; Humans; Immunity, Innate; Immunologic Factors; Indoles; Leukotriene Antagonists; Monocytes; Neutrophils; NF-kappa B; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds | 2014 |
Clinical effectiveness and safety of montelukast in asthma. What are the conclusions from clinical trials and meta-analyses?
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Child; Clinical Trials as Topic; Cyclopropanes; Glucocorticoids; Humans; Medication Adherence; Quality of Life; Quinolines; Sulfides | 2014 |
Montelukast-induced adverse drug reactions: a review of case reports in the literature.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Risk Factors; Sulfides | 2014 |
Symptomatic treatment of the cough in whooping cough.
Topics: Acetates; Adolescent; Adult; Albuterol; Anti-Inflammatory Agents; Bordetella pertussis; Child; Cough; Cyclopropanes; Dexamethasone; Diphenhydramine; Histamine H1 Antagonists; Humans; Immunoglobulins; Length of Stay; Quinolines; Randomized Controlled Trials as Topic; Sulfides; Whooping Cough | 2014 |
[Meta-analysis of leukotriene receptor antagonist montelukast in the treatment of allergic rhinitis].
Topics: Acetates; Cyclopropanes; Drug Therapy, Combination; Humans; Leukotriene Antagonists; Loratadine; Nose; Quality of Life; Quinolines; Rhinitis, Allergic; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sulfides; Surveys and Questionnaires; Treatment Outcome | 2014 |
Montelukast in paediatric asthma: where we are now and what still needs to be done?
Topics: Acetates; Administration, Inhalation; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Glucocorticoids; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2015 |
Leukotriene inhibitors for bronchiolitis in infants and young children.
Topics: Acetates; Bronchiolitis; Cyclopropanes; Humans; Infant; Length of Stay; Leukotriene Antagonists; Quinolines; Randomized Controlled Trials as Topic; Sulfides | 2015 |
New cellular and molecular targets for the treatment of portal hypertension.
Topics: Acetates; Antioxidants; Biopterins; Chenodeoxycholic Acid; Cyclopropanes; Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Portal; Leukotriene Antagonists; Liver Circulation; Liver Cirrhosis; Microvessels; Molecular Targeted Therapy; Naphthalenes; Neovascularization, Pathologic; Propionates; Quinolines; Sulfides; Vascular Resistance | 2015 |
[Recent advances in allergic rhinitis].
Topics: Acetates; Allergens; Anti-Inflammatory Agents; Asthma; Child; Cyclopropanes; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Immunotherapy; Inflammation; Leukotriene Antagonists; Prevalence; Quinolines; Rhinitis, Allergic; Sulfides | 2015 |
Recent advances in paediatric respiratory medicine.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Bronchopulmonary Dysplasia; Ciliary Motility Disorders; Cyclopropanes; Humans; Lung Diseases, Interstitial; Medication Adherence; Pediatrics; Pulmonary Medicine; Quinolines; Saline Solution, Hypertonic; Sleep Apnea, Obstructive; Sulfides | 2016 |
Leukotriene receptor antagonists as maintenance and intermittent therapy for episodic viral wheeze in children.
Topics: Acetates; Child, Preschool; Common Cold; Cyclopropanes; Humans; Leukotriene Antagonists; Maintenance Chemotherapy; Quinolines; Randomized Controlled Trials as Topic; Respiratory Sounds; Respiratory Tract Infections; Sulfides; Time Factors; Virus Diseases | 2015 |
Leukotriene receptor antagonists as maintenance or intermittent treatment in pre-school children with episodic viral wheeze.
Topics: Acetates; Adrenal Cortex Hormones; Child, Preschool; Cyclopropanes; Humans; Leukotriene Antagonists; Maintenance Chemotherapy; Quinolines; Respiratory Sounds; Respiratory Tract Infections; Sulfides; Virus Diseases | 2016 |
Postnasal drip and postnasal drip-related cough.
Topics: Acetates; Capsaicin; Chronic Disease; Cough; Cyclopropanes; Humans; Leukotriene Antagonists; Mucus; Nasal Mucosa; Quinolines; Rhinitis; Sensory System Agents; Sulfides; Viscosity | 2016 |
Montelukast-induced metamorphopsia in a pediatric patient: A case report and a pharmacovigilance database analysis.
Topics: Acetates; Asthma; Child; Cyclopropanes; Databases, Factual; Evidence-Based Medicine; Female; Humans; Immunosuppressive Agents; Pharmacovigilance; Quinolines; Sulfides; Vision Disorders; Withholding Treatment | 2016 |
Montelukast medicines of today and tomorrow: from molecular pharmaceutics to technological formulations.
Topics: Acetates; Administration, Oral; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Biological Availability; Chemistry, Pharmaceutical; Cyclopropanes; Drug Delivery Systems; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2016 |
The efficacy and safety of H1-antihistamine versus Montelukast for allergic rhinitis: A systematic review and meta-analysis.
Topics: Acetates; Cyclopropanes; Drug Therapy, Combination; Histamine Antagonists; Humans; Placebos; Publication Bias; Quality of Life; Quinolines; Receptors, Histamine H1; Rhinitis, Allergic; Sulfides; Surveys and Questionnaires; Treatment Outcome | 2016 |
Exercise intolerance and exercise-induced bronchoconstriction in children.
Topics: Acetates; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Bronchoconstriction; Child; Cyclopropanes; Energy Metabolism; Exercise; Humans; Oxygen; Pulmonary Gas Exchange; Quinolines; Respiratory Hypersensitivity; Sulfides | 2017 |
[Therapeutic effect and safety of montelukast sodium combined with budesonide in children with cough variant asthma: a Meta analysis].
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Budesonide; Child; Cough; Cyclopropanes; Drug Therapy, Combination; Humans; Quinolines; Sulfides | 2016 |
A shocking diagnosis.
Topics: Acetates; Aged; Anti-Inflammatory Agents; Cyclopropanes; Diagnosis, Differential; Humans; Hypotension; Leukotriene Antagonists; Male; Mastocytosis, Systemic; Prednisone; Quinolines; Sulfides; Tachycardia | 2017 |
The leukotriene receptor antagonist montelukast and its possible role in the cardiovascular field.
Topics: Acetates; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cardiovascular Diseases; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Signal Transduction; Sulfides | 2017 |
[Chronic urticaria in childhood : Rational diagnostics and treatment].
Topics: Acetates; Angioedema; Child; Child, Preschool; Chronic Disease; Cyclopropanes; Cyclosporine; Diagnosis, Differential; Guideline Adherence; Histamine Antagonists; Humans; Infant; Long-Term Care; Omalizumab; Quinolines; Skin; Sulfides; Urticaria | 2017 |
A meta-analysis of montelukast for recurrent wheeze in preschool children.
Topics: Acetates; Anti-Asthmatic Agents; Child; Child, Preschool; Cyclopropanes; Humans; Infant; Models, Statistical; Quinolines; Recurrence; Respiratory Sounds; Respiratory Tract Diseases; Sulfides; Treatment Outcome | 2017 |
Therapeutic effects of different drugs on obstructive sleep apnea/hypopnea syndrome in children.
Topics: Acetates; Bayes Theorem; Bronchodilator Agents; Budesonide; Child; Child, Preschool; Cyclopropanes; Female; Fluticasone; Humans; Male; Prognosis; Quinolines; Randomized Controlled Trials as Topic; Risk Assessment; Severity of Illness Index; Sleep Apnea, Obstructive; Sulfides; Treatment Outcome | 2017 |
Emerging therapies for atopic dermatitis: The prostaglandin/leukotriene pathway.
Topics: Acetates; Adult; Animals; Cyclopropanes; Dermatitis, Atopic; Female; Forecasting; Humans; Hydroxyurea; Leukotriene Antagonists; Male; Molecular Targeted Therapy; Prostaglandin Antagonists; Quinolines; Severity of Illness Index; Sulfides; Treatment Outcome | 2018 |
Interventions for autumn exacerbations of asthma in children.
Topics: Acetates; Adrenal Cortex Hormones; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Behavior Therapy; Child; Chromones; Cyclopropanes; Disease Progression; Humans; Leukotriene Antagonists; Omalizumab; Quinolines; Randomized Controlled Trials as Topic; Seasons; Sulfides | 2018 |
Question 2: Is there a role for Montelukast in the management of viral-induced wheeze in preschool children?
Topics: Acetates; Anti-Asthmatic Agents; Child, Preschool; Cyclopropanes; Evidence-Based Medicine; Humans; Leukotriene Antagonists; Quinolines; Respiratory Sounds; Respiratory Tract Infections; Sulfides; Virus Diseases | 2018 |
Interventions for autumn exacerbations of asthma in children.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Disease Progression; Humans; Omalizumab; Quinolines; Seasons; Sulfides | 2018 |
A systematic review on the off-label use of montelukast in atopic dermatitis treatment.
Topics: Acetates; Cyclopropanes; Dermatitis, Atopic; Humans; Immunosuppressive Agents; Leukotriene Antagonists; Off-Label Use; Quinolines; Randomized Controlled Trials as Topic; Sulfides | 2018 |
Potential role of leukotriene receptor antagonists in reducing cardiovascular and cerbrovascular risk: A systematic review of human clinical trials and in vivo animal studies.
Topics: Acetates; Animals; Cardiovascular Diseases; Cardiovascular System; Cerebrovascular Disorders; Clinical Trials as Topic; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Risk Factors; Sulfides | 2018 |
Targeting cysteinyl-leukotrienes in abdominal aortic aneurysm.
Topics: Acetates; Aortic Aneurysm, Abdominal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Blood Vessels; Cyclopropanes; Cysteine; Humans; Leukotriene Antagonists; Leukotrienes; Quinolines; Receptors, Leukotriene; Sulfides; Thrombosis | 2018 |
Leukotriene receptor antagonists for eczema.
Topics: Acetates; Administration, Oral; Cyclopropanes; Eczema; Humans; Leukotriene Antagonists; Quinolines; Randomized Controlled Trials as Topic; Sulfides | 2018 |
Daily inhaled corticosteroids or montelukast for preschoolers with asthma or recurrent wheezing: A systematic review.
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Child, Preschool; Cyclopropanes; Drug Therapy, Combination; Hospitalization; Humans; Infant; Leukotriene Antagonists; Prospective Studies; Quinolines; Recurrence; Respiratory Sounds; Sulfides | 2018 |
Montelukast and Nasal Corticosteroids to Treat Pediatric Obstructive Sleep Apnea: A Systematic Review and Meta-analysis.
Topics: Acetates; Administration, Intranasal; Adolescent; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Child; Child, Preschool; Cyclopropanes; Humans; Quinolines; Sleep Apnea, Obstructive; Sulfides | 2019 |
Pediatric asthma: Principles and treatment.
Topics: Acetates; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cough; Cyclopropanes; Humans; Inflammation; Pediatrics; Quinolines; Respiratory Sounds; Sulfides | 2019 |
The leukotriene receptor antagonist Montelukast can induce adverse skin reactions in asthmatic patients.
Topics: Acetates; Adult; Aged; Anti-Asthmatic Agents; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Skin; Sulfides | 2020 |
A Review of Different Analytical Techniques for Fexofenadine Hydrochloride and Montelukast Sodium in Different Matrices.
Topics: Acetates; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Chemistry Techniques, Analytical; Cyclopropanes; Drug Monitoring; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Quinolines; Sulfides; Terfenadine | 2021 |
Anti-inflammatory medications for obstructive sleep apnoea in children.
Topics: Acetates; Adenoidectomy; Adolescent; Anti-Inflammatory Agents; Child; Child, Preschool; Cyclopropanes; Female; Humans; Infant; Male; Quinolines; Randomized Controlled Trials as Topic; Sleep Apnea, Obstructive; Sulfides; Tonsillectomy | 2020 |
Suppressive Effect of Leukotriene Antagonists on Capsular Contracture in Patients Who Underwent Breast Surgery with Prosthesis: A Meta-Analysis.
Topics: Acetates; Adolescent; Adult; Breast Implantation; Breast Implants; Cyclopropanes; Female; Humans; Implant Capsular Contracture; Indoles; Leukotriene Antagonists; Middle Aged; Phenylcarbamates; Quinolines; Randomized Controlled Trials as Topic; Risk Factors; Sulfides; Sulfonamides; Tosyl Compounds; Young Adult | 2020 |
Anti-inflammatory medications for the treatment of pediatric obstructive sleep apnea.
Topics: Acetates; Administration, Intranasal; Administration, Oral; Adolescent; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Child; Child, Preschool; Cyclopropanes; Humans; Infant; Leukotriene Antagonists; Quinolines; Sleep Apnea, Obstructive; Sulfides; Treatment Outcome | 2020 |
What's new in atopic eczema? An analysis of systematic reviews published in 2018. Part 2: systemic therapies.
Topics: Acetates; Adrenal Cortex Hormones; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biological Therapy; Child; Complementary Therapies; Cyclopropanes; Cyclosporine; Cytochrome P-450 CYP1A2 Inducers; Dermatitis, Atopic; Eczema; Humans; Immunosuppressive Agents; Janus Kinase Inhibitors; Naltrexone; Narcotic Antagonists; Omalizumab; Placebo Effect; Probiotics; Quinolines; Sulfides; Ustekinumab; Vitamin D | 2020 |
Efficacy of Montelukast in Allergic Rhinitis Treatment: A Systematic Review and Meta-Analysis.
Topics: Acetates; Administration, Intranasal; Administration, Oral; Adrenal Cortex Hormones; Cyclopropanes; Drug Therapy, Combination; Histamine H1 Antagonists; Humans; Leukotriene Antagonists; Photoperiod; Quality of Life; Quinolines; Randomized Controlled Trials as Topic; Rhinitis, Allergic; Severity of Illness Index; Sulfides; Treatment Outcome | 2020 |
Leukotriene D
Topics: Acetates; Airway Remodeling; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Cyclopropanes; Cysteine; Gene Expression; Humans; Hypersensitivity; Indoles; Inflammation Mediators; Leukotriene Antagonists; Leukotriene D4; Leukotrienes; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds | 2020 |
The efficacy and safety of montelukast in children with obstructive sleep apnea: a systematic review and meta-analysis.
Topics: Acetates; Adenoids; Child; Cyclopropanes; Humans; Quinolines; Sleep Apnea, Obstructive; Sulfides | 2021 |
A Boxed Warning for Montelukast: The FDA Perspective.
Topics: Acetates; Cyclopropanes; Drug Labeling; Humans; Observational Studies as Topic; Quinolines; Sulfides; United States; United States Food and Drug Administration | 2021 |
Role of leukotriene pathway and montelukast in pulmonary and extrapulmonary manifestations of Covid-19: The enigmatic entity.
Topics: Acetates; COVID-19; COVID-19 Drug Treatment; Cyclopropanes; Cytokine Release Syndrome; Humans; Leukotriene Antagonists; Leukotrienes; Lung Diseases; Quinolines; Receptors, Leukotriene; Signal Transduction; Sulfides | 2021 |
Potential Effects of Leukotriene Receptor Antagonist Montelukast in Treatment of Neuroinflammation in Parkinson's Disease.
Topics: Acetates; Anti-Inflammatory Agents; Astrocytes; Cyclopropanes; Humans; Inflammation; Leukotriene Antagonists; Lewy Bodies; Microglia; Parkinson Disease; Quinolines; Receptors, Leukotriene; Sulfides | 2021 |
Successful use of montelukast in eosinophilic gastroenteritis: a case report and a literature review.
Topics: Acetates; Adult; Cyclopropanes; Enteritis; Eosinophilia; Female; Gastritis; Gastroenteritis; Humans; Middle Aged; Quinolines; Sulfides | 2021 |
Possible Therapeutic Potential of Cysteinyl Leukotriene Receptor Antagonist Montelukast in Treatment of SARS-CoV-2-Induced COVID-19.
Topics: Acetates; Adenosine Monophosphate; Alanine; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Receptors, Leukotriene; Sulfides | 2021 |
Eicosanoid receptors as therapeutic targets for asthma.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Benzoquinones; Biomarkers; Cyclopropanes; Heptanoic Acids; Humans; Lung; Mice; Quinolines; Receptors, Eicosanoid; Sulfides | 2021 |
Montelukast and Coronavirus Disease 2019: A Scoping Review.
Topics: Acetates; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; SARS-CoV-2; Sulfides; Treatment Outcome | 2021 |
Targeted Delivery of Montelukast for the Treatment of Alzheimer's Disease.
Topics: Acetates; Alzheimer Disease; Cyclopropanes; Humans; Leukotrienes; Quinolines; Sulfides | 2022 |
Efficacy and safety of salmeterol/fluticasone compared with montelukast alone (or add-on therapy to fluticasone) in the treatment of bronchial asthma in children and adolescents: a systematic review and meta-analysis.
Topics: Acetates; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Albuterol; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Drug Therapy, Combination; Fluticasone; Humans; Quinolines; Salmeterol Xinafoate; Sulfides | 2021 |
Deprescribing montelukast in children with asthma: a systematic review.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Deprescriptions; Forced Expiratory Volume; Humans; Infant; Infant, Newborn; Quinolines; Sulfides | 2022 |
Montelukast as a potential treatment for COVID-19.
Topics: Acetates; Asthma; COVID-19; Cyclopropanes; Double-Blind Method; Humans; Leukotriene Antagonists; Quinolines; Randomized Controlled Trials as Topic; SARS-CoV-2; Sulfides | 2023 |
Neuropsychiatric events associated with montelukast in patients with asthma: a systematic review.
Topics: Acetates; Aged; Animals; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Humans; Quinolines | 2023 |
An efficacy and safety evaluation of montelukast + fluticasone propionate vs. fluticasone propionate in the treatment of cough variant asthma in children: a meta-analysis.
Topics: Acetates; Androstadienes; Anti-Asthmatic Agents; Asthma; Child; Cough; Cyclopropanes; Fluticasone; Humans; Quinolines | 2023 |
531 trial(s) available for phenyl acetate and montelukast
| Article | Year |
|---|---|
Single dose pharmacokinetics, safety and tolerability of MK-0476, a new leukotriene D4-receptor antagonist, in healthy volunteers.
Topics: Acetates; Administration, Oral; Adult; Cyclopropanes; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Male; Quinolines; Receptors, Dopamine; Safety; Sulfides; Time Factors | 1995 |
Pharmacokinetics, bioavailability, and safety of montelukast sodium (MK-0476) in healthy males and females.
Topics: Acetates; Administration, Oral; Adult; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Injections, Intravenous; Leukotriene Antagonists; Male; Membrane Proteins; Placebos; Quinolines; Receptors, Leukotriene; Sex Factors; Sulfides | 1996 |
Effects of montelukast (MK-0476), a new potent cysteinyl leukotriene (LTD4) receptor antagonist, in patients with chronic asthma.
Topics: Acetates; Adolescent; Adrenal Cortex Hormones; Adult; Asthma; Chronic Disease; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Leukotriene D4; Male; Membrane Proteins; Middle Aged; Quinolines; Receptors, Leukotriene; Sulfides | 1996 |
Montelukast causes prolonged, potent leukotriene D4-receptor antagonism in the airways of patients with asthma.
Topics: Acetates; Adult; Asthma; Bronchoconstriction; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Humans; Leukotriene Antagonists; Male; Membrane Proteins; Middle Aged; Quinolines; Receptors, Leukotriene; Sulfides; Time Factors; Treatment Outcome | 1997 |
Effects of montelukast (MK-0476); a potent cysteinyl leukotriene receptor antagonist, on bronchodilation in asthmatic subjects treated with and without inhaled corticosteroids.
Topics: Acetates; Adolescent; Adult; Albuterol; Analysis of Variance; Asthma; Bronchodilator Agents; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Quinolines; Receptors, Leukotriene B4; Sulfides | 1997 |
Metabolic profiles of montelukast sodium (Singulair), a potent cysteinyl leukotriene1 receptor antagonist, in human plasma and bile.
Topics: Acetates; Adult; Bile; Biotransformation; Chromatography, High Pressure Liquid; Cyclopropanes; Female; Humans; Interleukin-1; Leukotriene Antagonists; Male; Mass Spectrometry; Middle Aged; Quinolines; Sulfides | 1997 |
Dose-related protection of exercise bronchoconstriction by montelukast, a cysteinyl leukotriene-receptor antagonist, at the end of a once-daily dosing interval.
Topics: Acetates; Adult; Analysis of Variance; Area Under Curve; Bronchoconstriction; Cross-Over Studies; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Exercise; Humans; Middle Aged; Quinolines; Receptors, Leukotriene B4; Sulfides | 1997 |
Pharmacokinetics and bioavailability of montelukast sodium (MK-0476) in healthy young and elderly volunteers.
Topics: Acetates; Administration, Oral; Adult; Age Factors; Aged; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Cyclopropanes; Female; Half-Life; Humans; Male; Middle Aged; Quinolines; Sulfides | 1997 |
Increased urinary excretion of LTE4 after exercise and attenuation of exercise-induced bronchospasm by montelukast, a cysteinyl leukotriene receptor antagonist.
Topics: Acetates; Adolescent; Adult; Asthma, Exercise-Induced; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Exercise; Exercise Test; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Leukotriene E4; Male; Middle Aged; Quinolines; Sulfides | 1997 |
Montelukast for chronic asthma in 6- to 14-year-old children: a randomized, double-blind trial. Pediatric Montelukast Study Group.
Topics: Acetates; Adolescent; Adrenergic beta-Agonists; Analysis of Variance; Anti-Asthmatic Agents; Asthma; Child; Chronic Disease; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides | 1998 |
Montelukast, a once-daily leukotriene receptor antagonist, in the treatment of chronic asthma: a multicenter, randomized, double-blind trial. Montelukast Clinical Research Study Group.
Topics: Acetates; Adolescent; Adult; Aged; Analysis of Variance; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Respiration; Single-Blind Method; Sulfides; Treatment Outcome | 1998 |
Montelukast, a potent leukotriene receptor antagonist, causes dose-related improvements in chronic asthma. Montelukast Asthma Study Group.
Topics: Acetates; Adolescent; Adult; Aged; Asthma; Chronic Disease; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Middle Aged; Peak Expiratory Flow Rate; Quality of Life; Quinolines; Spirometry; Sulfides | 1998 |
Montelukast, a leukotriene-receptor antagonist, for the treatment of mild asthma and exercise-induced bronchoconstriction.
Topics: Acetates; Adolescent; Adrenergic beta-Agonists; Adult; Anti-Asthmatic Agents; Asthma, Exercise-Induced; Bronchial Provocation Tests; Bronchoconstriction; Cyclopropanes; Double-Blind Method; Exercise; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Methacholine Chloride; Middle Aged; Quinolines; Sulfides | 1998 |
New oral therapy for childhood asthma.
Topics: Acetates; Administration, Oral; Adolescent; Asthma; Child; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Long-Term Care; Male; Quinolines; Sulfides; Treatment Outcome | 1998 |
A placebo-controlled, dose-ranging study of montelukast, a cysteinyl leukotriene-receptor antagonist. Montelukast Asthma Study Group.
Topics: Acetates; Adolescent; Adult; Aged; Anti-Asthmatic Agents; Asthma; Consumer Product Safety; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Single-Blind Method; Sulfides; Treatment Outcome | 1998 |
Montelukast.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Drug Tolerance; Humans; Quinolines; Sulfides | 1998 |
Montelukast once daily inhibits exercise-induced bronchoconstriction in 6- to 14-year-old children with asthma.
Topics: Acetates; Administration, Oral; Adolescent; Analysis of Variance; Asthma; Bronchoconstriction; Child; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Physical Exertion; Placebos; Quinolines; Sulfides; Tablets; Time Factors; Treatment Outcome | 1998 |
[Leukotriene receptor antagonist effective in chronic asthma].
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Chronic Disease; Cyclopropanes; Double-Blind Method; Humans; Leukotriene Antagonists; Placebos; Quinolines; Sulfides; Time Factors | 1998 |
The effect of montelukast (MK-0476), a cysteinyl leukotriene receptor antagonist, on allergen-induced airway responses and sputum cell counts in asthma.
Topics: Acetates; Adult; Allergens; Anti-Asthmatic Agents; Asthma; Blood Proteins; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cell Count; Cell Survival; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Eosinophil Granule Proteins; Forced Expiratory Volume; Humans; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Leukotriene Antagonists; Male; Patient Compliance; Quinolines; Ribonucleases; Sputum; Sulfides; Treatment Outcome | 1999 |
Oral montelukast, inhaled beclomethasone, and placebo for chronic asthma. A randomized, controlled trial. Montelukast/Beclomethasone Study Group.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Anti-Asthmatic Agents; Asthma; Beclomethasone; Blood Cell Count; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Eosinophils; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Peak Expiratory Flow Rate; Placebos; Quality of Life; Quinolines; Sulfides | 1999 |
Effect of montelukast on single-dose theophylline pharmacokinetics.
Topics: Acetates; Administration, Oral; Adult; Anti-Asthmatic Agents; Bronchodilator Agents; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Interactions; Drug Monitoring; Humans; Injections, Intravenous; Leukotriene Antagonists; Male; Quinolines; Sulfides; Theophylline; Time Factors | 1998 |
Effect of montelukast on the pharmacokinetics and pharmacodynamics of warfarin in healthy volunteers.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Anticoagulants; Area Under Curve; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Interactions; Humans; International Normalized Ratio; Leukotriene Antagonists; Male; Prothrombin Time; Quinolines; Sulfides; Warfarin | 1999 |
Randomised, placebo controlled trial of effect of a leukotriene receptor antagonist, montelukast, on tapering inhaled corticosteroids in asthmatic patients.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Chronic Disease; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Female; Glucocorticoids; Humans; Leukotriene Antagonists; Lung; Male; Middle Aged; Quinolines; Single-Blind Method; Sulfides | 1999 |
Montelukast dose selection in 6- to 14-year-olds: comparison of single-dose pharmacokinetics in children and adults.
Topics: Acetates; Administration, Oral; Adolescent; Adult; Area Under Curve; Asthma; Child; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Female; Half-Life; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides; Tablets; Tablets, Enteric-Coated; Treatment Outcome | 1999 |
Effect of multiple doses of montelukast, a CysLT1 receptor antagonist, on digoxin pharmacokinetics in healthy volunteers.
Topics: Acetates; Adult; Anti-Arrhythmia Agents; Cross-Over Studies; Cyclopropanes; Digoxin; Double-Blind Method; Drug Interactions; Electrocardiography; Female; Humans; Hypokalemia; Immunochemistry; Leukotriene Antagonists; Male; Middle Aged; Patient Dropouts; Quinolines; Sulfides; Time Factors | 1999 |
Montelukast versus salmeterol in patients with asthma and exercise-induced bronchoconstriction. Montelukast/Salmeterol Exercise Study Group.
Topics: Acetates; Adolescent; Adult; Albuterol; Asthma, Exercise-Induced; Bronchial Diseases; Bronchodilator Agents; Constriction, Pathologic; Cyclopropanes; Double-Blind Method; Female; Humans; Male; Middle Aged; Quinolines; Salmeterol Xinafoate; Single-Blind Method; Sulfides | 1999 |
Montelukast reduces airway eosinophilic inflammation in asthma: a randomized, controlled trial.
Topics: Acetates; Adult; Asthma; Cyclopropanes; Double-Blind Method; Eosinophils; Female; Humans; Leukocyte Count; Leukotriene Antagonists; Male; Middle Aged; Pulmonary Eosinophilia; Quinolines; Respiratory Function Tests; Respiratory Tract Diseases; Safety; Sputum; Sulfides; Treatment Outcome | 1999 |
What are minimal important changes for asthma measures in a clinical trial?
Topics: Acetates; Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Adult; Age Factors; Aged; Asthma; Circadian Rhythm; Cyclopropanes; Double-Blind Method; Epidemiologic Measurements; Female; Humans; Leukotriene Antagonists; Lung; Male; Middle Aged; Quinolines; Respiratory Function Tests; Severity of Illness Index; Sex Factors; Single-Blind Method; Sulfides | 1999 |
NO in exhaled air of asthmatic children is reduced by the leukotriene receptor antagonist montelukast.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Breath Tests; Child; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Forced Expiratory Volume; Glucocorticoids; Humans; Leukotriene Antagonists; Maximal Midexpiratory Flow Rate; Nitric Oxide; Quinolines; Spirometry; Sulfides | 1999 |
Exhaled nitric oxide before and after montelukast sodium therapy in school-age children with chronic asthma: a preliminary study.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Analysis of Variance; Asthma; Biomarkers; Breath Tests; Child; Cross-Over Studies; Cyclopropanes; Female; Follow-Up Studies; Humans; Leukotriene Antagonists; Male; Nitric Oxide; Quinolines; Reference Values; Respiratory Function Tests; Sulfides; Treatment Outcome | 1999 |
Montelukast added to inhaled beclomethasone in treatment of asthma. Montelukast/Beclomethasone Additivity Group.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Aged; Anti-Asthmatic Agents; Asthma; Beclomethasone; Chronic Disease; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Forced Expiratory Volume; Glucocorticoids; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Single-Blind Method; Sulfides | 1999 |
Montelukast, a leukotriene receptor antagonist, reduces the concentration of leukotrienes in the respiratory tract of children with persistent asthma.
Topics: Acetates; Asthma; Beclomethasone; Blood Proteins; Child; Cromolyn Sodium; Cross-Over Studies; Cyclopropanes; Eosinophil Granule Proteins; Female; Humans; Inflammation Mediators; Leukotriene Antagonists; Leukotrienes; Male; Quinolines; Respiratory System; Ribonucleases; Sulfides | 1999 |
Oral montelukast compared with inhaled salmeterol to prevent exercise-induced bronchoconstriction. A randomized, double-blind trial. Exercise Study Group.
Topics: Acetates; Administration, Oral; Adolescent; Adult; Albuterol; Area Under Curve; Asthma, Exercise-Induced; Bronchoconstriction; Bronchodilator Agents; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Salmeterol Xinafoate; Sulfides | 2000 |
Comparison of the effects of intravenous and oral montelukast on airway function: a double blind, placebo controlled, three period, crossover study in asthmatic patients.
Topics: Acetates; Adolescent; Adult; Analysis of Variance; Anti-Asthmatic Agents; Asthma; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Quinolines; Sulfides | 2000 |
Montelukast in the prophylaxis of migraine: a potential role for leukotriene modifiers.
Topics: Acetates; Adolescent; Adult; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Migraine Disorders; Prospective Studies; Quinolines; Sulfides | 2000 |
Additive bronchoprotective and bronchodilator effects with single doses of salmeterol and montelukast in asthmatic patients receiving inhaled corticosteroids.
Topics: Acetates; Adenosine Monophosphate; Administration, Inhalation; Administration, Oral; Adrenergic beta-Agonists; Albuterol; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cross-Over Studies; Cyclopropanes; Drug Therapy, Combination; Glucocorticoids; Humans; Leukotriene Antagonists; Quinolines; Respiratory Function Tests; Salmeterol Xinafoate; Single-Blind Method; Sulfides; Treatment Outcome | 2000 |
Concomitant montelukast and loratadine as treatment for seasonal allergic rhinitis: a randomized, placebo-controlled clinical trial.
Topics: Acetates; Adolescent; Adult; Aged; Anti-Allergic Agents; Cyclopropanes; Drug Therapy, Combination; Female; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Placebos; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides; Time Factors | 2000 |
Evaluation of treatment response in patients with seasonal allergic rhinitis using domiciliary nasal peak inspiratory flow.
Topics: Acetates; Adolescent; Adult; Aged; Anti-Allergic Agents; Cetirizine; Cyclopropanes; Drug Therapy, Combination; Histamine H1 Antagonists; Humans; Inspiratory Capacity; Leukotriene Antagonists; Middle Aged; Mometasone Furoate; Pollen; Pregnadienediols; Quinolines; Rhinitis, Allergic, Seasonal; Self Administration; Single-Blind Method; Sulfides; Treatment Outcome | 2000 |
Bronchoprotection with a leukotriene receptor antagonist in asthmatic preschool children.
Topics: Acetates; Asthma; Child, Preschool; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2000 |
Montelukast or salmeterol combined with an inhaled steroid in adult asthma: design and rationale of a randomized, double-blind comparative study (the IMPACT Investigation of Montelukast as a Partner Agent for Complementary Therapy-trial).
Topics: Acetates; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Middle Aged; Peak Expiratory Flow Rate; Quality of Life; Quinolines; Quinolones; Sulfides; Surveys and Questionnaires | 2000 |
Leukotriene receptor antagonists: efficacy and safety in children with asthma.
Topics: Acetates; Activities of Daily Living; Adolescent; Asthma; Child; Cyclopropanes; Double-Blind Method; Emotions; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Quality of Life; Quinolines; Sulfides; Treatment Outcome | 2000 |
Montelukast does not affect exercise performance at subfreezing temperature in highly trained non-asthmatic endurance athletes.
Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Cold Temperature; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Humans; Male; Oxygen Consumption; Physical Endurance; Quinolines; Running; Spirometry; Sulfides | 2000 |
Montelukast, a leukotriene receptor antagonist, in combination with loratadine, a histamine receptor antagonist, in the treatment of chronic asthma.
Topics: Acetates; Adolescent; Adult; Aged; Asthma; Chronic Disease; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Histamine H1 Antagonists; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Quinolines; Sulfides | 2000 |
Antiasthmatic effects of mediator blockade versus topical corticosteroids in allergic rhinitis and asthma.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Anti-Asthmatic Agents; Asthma; Bronchial Provocation Tests; Budesonide; Cetirizine; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Forced Expiratory Volume; Humans; Inflammation Mediators; Leukotriene Antagonists; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides | 2000 |
Fluticasone propionate/salmeterol combination provides more effective asthma control than low-dose inhaled corticosteroid plus montelukast.
Topics: Acetates; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Adult; Albuterol; Androstadienes; Asthma; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Fluticasone; Humans; Male; Patient Compliance; Quinolines; Salmeterol Xinafoate; Sulfides | 2000 |
The leukotriene antagonist montelukast as a therapeutic agent for atopic dermatitis.
Topics: Acetates; Adolescent; Adult; Cyclopropanes; Dermatitis, Atopic; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Pilot Projects; Quinolines; Sulfides; Treatment Outcome | 2001 |
Effects of monotherapy with intra-nasal corticosteroid or combined oral histamine and leukotriene receptor antagonists in seasonal allergic rhinitis.
Topics: Acetates; Administration, Intranasal; Anti-Inflammatory Agents; Cetirizine; Cross-Over Studies; Cyclopropanes; Drug Therapy, Combination; Histamine H1 Antagonists; Humans; Leukotriene Antagonists; Mometasone Furoate; Pregnadienediols; Quinolines; Rhinitis, Allergic, Seasonal; Single-Blind Method; Sulfides; Treatment Outcome | 2001 |
Anti-inflammatory and lung function effects of montelukast in asthmatic volunteers exposed to sulfur dioxide.
Topics: Acetates; Adult; Asthma; Cyclopropanes; Double-Blind Method; Eosinophils; Female; Forced Expiratory Volume; Humans; Leukocyte Count; Leukotriene Antagonists; Lung; Male; Middle Aged; Quinolines; Sputum; Sulfides; Sulfur Dioxide | 2001 |
Comparison of montelukast and fexofenadine for chronic idiopathic urticaria.
Topics: Acetates; Adult; Aged; Chronic Disease; Cyclopropanes; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Sulfides; Terfenadine; Treatment Outcome; Urticaria | 2001 |
Suppression of the early and late cutaneous allergic responses using fexofenadine and montelukast.
Topics: Acetates; Adult; Allergens; Cyclopropanes; Depression, Chemical; Dermatitis, Allergic Contact; Drug Therapy, Combination; Female; Histamine; Humans; Injections; Leukotriene D4; Male; Middle Aged; Quinolines; Sulfides; Terfenadine; Time Factors | 2001 |
Low-dose fluticasone propionate compared with montelukast for first-line treatment of persistent asthma: a randomized clinical trial.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Androstadienes; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Cyclopropanes; Dose-Response Relationship, Drug; Female; Fluticasone; Humans; Male; Middle Aged; Quinolines; Sulfides | 2001 |
Comparison of asthma costs in patients starting fluticasone propionate compared to patients starting montelukast.
Topics: Acetates; Adolescent; Adult; Androstadienes; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Female; Fluticasone; Health Care Costs; Humans; Linear Models; Logistic Models; Male; Middle Aged; Quinolines; Regression Analysis; Retrospective Studies; Statistics, Nonparametric; Sulfides | 2001 |
Evaluation of salmeterol or montelukast as second-line therapy for asthma not controlled with inhaled corticosteroids.
Topics: Acetates; Adenosine Monophosphate; Administration, Inhalation; Administration, Topical; Adrenergic beta-Agonists; Adult; Albuterol; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Breath Tests; Bronchial Provocation Tests; Bronchodilator Agents; Cross-Over Studies; Cyclopropanes; Eosinophils; Female; Glucocorticoids; Humans; Leukocyte Count; Leukotriene Antagonists; Male; Nitric Oxide; Peak Expiratory Flow Rate; Quinolines; Respiratory Mechanics; Salmeterol Xinafoate; Single-Blind Method; Steroids; Sulfides | 2001 |
Montelukast added to budesonide in children with persistent asthma: a randomized, double-blind, crossover study.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Budesonide; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Forced Expiratory Volume; Humans; Predictive Value of Tests; Quality of Life; Quinolines; Sulfides; Treatment Outcome | 2001 |
A comparison of topical budesonide and oral montelukast in seasonal allergic rhinitis and asthma.
Topics: Acetates; Administration, Oral; Administration, Topical; Adult; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Biomarkers; Budesonide; Confidence Intervals; Cross-Over Studies; Cyclopropanes; Humans; Quinolines; Rhinitis, Allergic, Seasonal; Single-Blind Method; Sulfides | 2001 |
Fexofenadine decreases sensitivity to and montelukast improves recovery from inhaled mannitol.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Aged; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cyclopropanes; Double-Blind Method; Drug Interactions; Female; Forced Expiratory Volume; Histamine H1 Antagonists; Humans; Leukotriene Antagonists; Male; Mannitol; Middle Aged; Quinolines; Recovery of Function; Sulfides; Terfenadine; Time Factors | 2001 |
Montelukast dose selection in children ages 2 to 5 years: comparison of population pharmacokinetics between children and adults.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Area Under Curve; Asthma; Child; Child, Preschool; Cyclopropanes; Dosage Forms; Female; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2001 |
Long-term asthma control with oral montelukast and inhaled beclomethasone for adults and children 6 years and older.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Asthmatic Agents; Asthma; Beclomethasone; Child; Chronic Disease; Cyclopropanes; Double-Blind Method; Eosinophils; Female; Follow-Up Studies; Forced Expiratory Volume; Humans; Leukocyte Count; Leukotriene Antagonists; Male; Middle Aged; Predictive Value of Tests; Quinolines; Sulfides; Time | 2001 |
Addition of leukotriene antagonists to therapy in chronic persistent asthma: a randomised double-blind placebo-controlled trial.
Topics: Acetates; Adrenergic beta-Agonists; Adult; Aged; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Chronic Disease; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Leukotriene Antagonists; Male; Middle Aged; Peak Expiratory Flow Rate; Quinolines; Steroids; Sulfides | 2001 |
[Preventive monotherapy with montelukast versus DNCG in children with mild asthma. Results of and exploratory pilot study].
Topics: Acetates; Administration, Inhalation; Adolescent; Anti-Asthmatic Agents; Asthma; Child; Cromolyn Sodium; Cross-Over Studies; Cyclopropanes; Female; Forced Expiratory Volume; Humans; Male; Pilot Projects; Quinolines; Respiratory Function Tests; Sulfides | 2001 |
Montelukast in the treatment of children with moderate-to-severe atopic dermatitis: a pilot study.
Topics: Acetates; Activities of Daily Living; Administration, Oral; Adolescent; Child; Cyclopropanes; Dermatitis, Atopic; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Pilot Projects; Quinolines; Sulfides | 2001 |
Salmeterol powder provides significantly better benefit than montelukast in asthmatic patients receiving concomitant inhaled corticosteroid therapy.
Topics: Acetates; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Albuterol; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Powders; Quinolines; Salmeterol Xinafoate; Sulfides | 2001 |
Montelukast, a leukotriene receptor antagonist, for the treatment of persistent asthma in children aged 2 to 5 years.
Topics: Acetates; Administration, Oral; Analysis of Variance; Anti-Asthmatic Agents; Asthma; Child, Preschool; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Eosinophils; Female; Humans; Leukocyte Count; Leukotriene Antagonists; Male; Quality of Life; Quinolines; Sulfides; Tablets; Treatment Outcome | 2001 |
Comparison of fluticasone propionate-salmeterol combination therapy and montelukast in patients who are symptomatic on short-acting beta(2)-agonists alone.
Topics: Acetates; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Androstadienes; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Fluticasone; Humans; Male; Middle Aged; Quinolines; Salmeterol Xinafoate; Sulfides | 2001 |
In patients with asthma that is not well controlled with inhaled steroids, does salmeterol (Serevent) or montelukast (Singulair) offer better symptom relief?
Topics: Acetates; Adrenal Cortex Hormones; Albuterol; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Cross-Over Studies; Cyclopropanes; Drug Therapy, Combination; Humans; Quinolines; Salmeterol Xinafoate; Sulfides | 2001 |
Efficacy of leukotriene receptor antagonist in chronic urticaria. A double-blind, placebo-controlled comparison of treatment with montelukast and cetirizine in patients with chronic urticaria with intolerance to food additive and/or acetylsalicylic acid.
Topics: Acetates; Adolescent; Adult; Aged; Aspirin; Cetirizine; Chronic Disease; Cyclopropanes; Double-Blind Method; Female; Food Additives; Food Hypersensitivity; Histamine H1 Antagonists; Humans; Incidence; Italy; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Sleep Stages; Sulfides; Treatment Outcome; Urticaria | 2001 |
Effects of topical corticosteroid and combined mediator blockade on domiciliary and laboratory measurements of nasal function in seasonal allergic rhinitis.
Topics: Acetates; Administration, Inhalation; Administration, Intranasal; Adult; Airway Resistance; Anti-Allergic Agents; Anti-Inflammatory Agents; Asthma; Budesonide; Cetirizine; Cross-Over Studies; Cyclopropanes; Female; Glucocorticoids; Histamine H1 Antagonists; Humans; Leukotriene Antagonists; Male; Nasal Obstruction; Quinolines; Rhinitis, Allergic, Seasonal; Rhinomanometry; Rhinometry, Acoustic; Sulfides | 2001 |
[Montelukast in treatment mild chronic asthma].
Topics: Acetates; Adolescent; Asthma; Child; Chronic Disease; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Predictive Value of Tests; Quinolines; Spirometry; Sulfides; Treatment Outcome | 2001 |
Oral montelukast versus inhaled beclomethasone in 6- to 11-year-old children with asthma: results of an open-label extension study evaluating long-term safety, satisfaction, and adherence with therapy.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adolescent; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Beclomethasone; Child; Cross-Over Studies; Cyclopropanes; Female; Forced Expiratory Volume; Health Resources; Humans; Male; Patient Compliance; Patient Satisfaction; Quinolines; Sulfides; Time Factors; Treatment Outcome | 2001 |
[The effect of triamcinolone, montelukast and formoterol on serum levels of il-4, IgE and clinical parameters in children with asthma].
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchodilator Agents; Child; Cyclopropanes; Double-Blind Method; Ethanolamines; Female; Formoterol Fumarate; Humans; Immunoglobulin E; Interleukin-4; Male; Quinolines; Sulfides; Triamcinolone | 2001 |
Leukotriene receptor antagonists (Montelukast) in the treatment of asthma crisis: preliminary results of a double-blind placebo controlled randomized study.
Topics: Acetates; Adrenal Cortex Hormones; Adult; Aminophylline; Anti-Asthmatic Agents; Bronchodilator Agents; Cyclopropanes; Double-Blind Method; Emergency Medical Services; Female; Humans; Length of Stay; Leukotriene Antagonists; Male; Peak Expiratory Flow Rate; Quinolines; Status Asthmaticus; Sulfides; Treatment Outcome | 2001 |
Improvement of aspirin-intolerant asthma by montelukast, a leukotriene antagonist: a randomized, double-blind, placebo-controlled trial.
Topics: Acetates; Administration, Oral; Adult; Aged; Anti-Asthmatic Agents; Aspirin; Asthma; Cyclopropanes; Double-Blind Method; Drug Hypersensitivity; Drug Monitoring; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Leukotriene E4; Male; Middle Aged; Peak Expiratory Flow Rate; Quality of Life; Quinolines; Sulfides; Treatment Outcome | 2002 |
Comparative efficacy and anti-inflammatory profile of once-daily therapy with leukotriene antagonist or low-dose inhaled corticosteroid in patients with mild persistent asthma.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Asthma; Bronchial Hyperreactivity; Cross-Over Studies; Cyclopropanes; Drug Administration Schedule; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Single-Blind Method; Sulfides; Triamcinolone | 2002 |
Marginal utility of montelukast for persistent asthma.
Topics: Acetates; Adolescent; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Humans; Leukotriene Antagonists; Middle Aged; Quinolines; Retrospective Studies; Sulfides; Treatment Outcome | 2002 |
A randomized, double-blind trial of the effect of treatment with montelukast on bronchial hyperresponsiveness and serum eosinophilic cationic protein (ECP), soluble interleukin 2 receptor (sIL-2R), IL-4, and soluble intercellular adhesion molecule 1 (sICA
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Blood Proteins; Bronchial Hyperreactivity; Child; Cyclopropanes; Double-Blind Method; Eosinophil Granule Proteins; Female; Humans; Intercellular Adhesion Molecule-1; Interleukin-4; Leukotriene Antagonists; Male; Quinolines; Receptors, Interleukin-2; Ribonucleases; Sulfides | 2002 |
Fluticasone propionate/salmeterol combination compared with montelukast for the treatment of persistent asthma.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Chronic Disease; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Fluticasone; Humans; Male; Middle Aged; Quinolines; Salmeterol Xinafoate; Sulfides | 2002 |
Reduction of eosinophilic inflammation in the airways of patients with asthma using montelukast.
Topics: Acetates; Adult; Asthma; Bronchi; Bronchial Hyperreactivity; Cell Count; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Eosinophils; Humans; Inflammation; Leukotriene Antagonists; Middle Aged; Quinolines; Respiratory Function Tests; Sputum; Sulfides | 2002 |
Role of cysteinyl leukotrienes in adenosine 5'-monophosphate induced bronchoconstriction in asthma.
Topics: Acetates; Adenosine Monophosphate; Adult; Anti-Asthmatic Agents; Asthma; Bronchoconstriction; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Leukotriene E4; Male; Membrane Proteins; Middle Aged; Quinolines; Receptors, Leukotriene; Sulfides | 2002 |
A randomized, double-blind trial of the effect of glucocorticoid, antileukotriene and beta-agonist treatment on IL-10 serum levels in children with asthma.
Topics: Acetates; Adolescent; Adrenergic beta-Agonists; Anti-Asthmatic Agents; Asthma; Blood Proteins; Child; Cyclopropanes; Double-Blind Method; Eosinophil Granule Proteins; Eosinophils; Ethanolamines; Female; Forced Expiratory Volume; Formoterol Fumarate; Glucocorticoids; Humans; Interleukin-10; Leukocyte Count; Leukotriene Antagonists; Male; Quinolines; Ribonucleases; Sulfides; Triamcinolone | 2002 |
The efficacy of montelukast in the treatment of cat allergen-induced asthma in children.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Child; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Glycoproteins; Humans; Male; Quinolines; Respiratory System; Sulfides | 2002 |
[Spirometry evaluation of montelukast treatment in children with bronchial asthma].
Topics: Acetates; Adolescent; Asthma; Child; Cyclopropanes; Female; Humans; Male; Quinolines; Spirometry; Sulfides; Treatment Outcome | 2002 |
[The effect of triamcinolone acetonide, montelukast, nedocromil sodium, formoterol on levels levels of sICAM-1, sIL-2R in serum and clinical course of asthma in children].
Topics: Acetates; Adolescent; Asthma; Biomarkers; Child; Cyclopropanes; Double-Blind Method; Ethanolamines; Formoterol Fumarate; Humans; Intercellular Adhesion Molecule-1; Interleukin-2 Receptor alpha Subunit; Nedocromil; Quinolines; Receptors, Interleukin; Sulfides; Triamcinolone Acetonide | 2002 |
Effect of montelukast on exhaled NO in asthmatic children exposed to relevant allergens.
Topics: Acetates; Adolescent; Allergens; Androstadienes; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Breath Tests; Child; Cyclopropanes; Dust; Fluticasone; Humans; Leukotriene Antagonists; Mites; Nitric Oxide; Quinolines; Respiratory Function Tests; Respiratory Hypersensitivity; Sulfides; Treatment Outcome | 2002 |
A comparison of once daily fexofenadine versus the combination of montelukast plus loratadine on domiciliary nasal peak flow and symptoms in seasonal allergic rhinitis.
Topics: Acetates; Adult; Anti-Allergic Agents; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Humans; Leukotriene Antagonists; Loratadine; Nasal Cavity; Poaceae; Pollen; Pulmonary Ventilation; Quinolines; Rhinitis, Allergic, Seasonal; Single-Blind Method; Skin Tests; Sulfides; Terfenadine | 2002 |
Efficacy and safety of low-dose fluticasone propionate compared with montelukast for maintenance treatment of persistent asthma.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Aged; Androstadienes; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Chronic Disease; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fluticasone; Headache; Humans; Male; Middle Aged; Nebulizers and Vaporizers; Patient Satisfaction; Quality of Life; Quinolines; Respiratory Tract Infections; Sleep Initiation and Maintenance Disorders; Sulfides; Treatment Outcome | 2002 |
[Effect of triamcinolone acetonide, montelukast, nedocromil sodium and formoterol on eosinophil blood counts, ECP serum levels and clinical progression of asthma in children].
Topics: Acetates; Adolescent; Anti-Inflammatory Agents; Asthma; Biomarkers; Blood Proteins; Child; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Eosinophil Granule Proteins; Eosinophils; Ethanolamines; Formoterol Fumarate; Humans; Leukocyte Count; Nedocromil; Quinolines; Ribonucleases; Sulfides; Triamcinolone Acetonide | 2002 |
Comparison of a nasal glucocorticoid, antileukotriene, and a combination of antileukotriene and antihistamine in the treatment of seasonal allergic rhinitis.
Topics: Acetates; Administration, Intranasal; Adult; Androstadienes; Circadian Rhythm; Cyclopropanes; Double-Blind Method; Eosinophils; Female; Fluticasone; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Nasal Mucosa; Pollen; Quinolines; Rhinitis; Rhinitis, Allergic, Seasonal; Sulfides | 2002 |
Efficacy and tolerability of montelukast alone or in combination with loratadine in seasonal allergic rhinitis: a multicenter, randomized, double-blind, placebo-controlled trial performed in the fall.
Topics: Acetates; Adult; Aged; Anti-Asthmatic Agents; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Quality of Life; Quinolines; Rhinitis, Allergic, Seasonal; Seasons; Sulfides | 2002 |
Montelukast for treating seasonal allergic rhinitis: a randomized, double-blind, placebo-controlled trial performed in the spring.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Cyclopropanes; Double-Blind Method; Eosinophils; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides | 2002 |
The combination of single-dose montelukast and loratadine on exercise-induced bronchospasm in children.
Topics: Acetates; Adolescent; Age Factors; Asthma; Asthma, Exercise-Induced; Child; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Exercise Test; Female; Forced Expiratory Volume; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Loratadine; Male; Quinolines; Sulfides | 2002 |
[Influence of montelukast on inhalational bronchial allergen provocation].
Topics: Acetates; Adult; Allergens; Anti-Asthmatic Agents; Asthma; Bronchial Provocation Tests; Cyclopropanes; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Quinolines; Reproducibility of Results; Sulfides | 2002 |
Leukotriene receptor antagonist, montelukast, can reduce the need for inhaled steroid while maintaining the clinical stability of asthmatic patients.
Topics: Acetates; Administration, Inhalation; Adult; Analysis of Variance; Asthma; Betamethasone; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Forced Expiratory Volume; Glucocorticoids; Humans; Leukotriene Antagonists; Male; Middle Aged; Peak Expiratory Flow Rate; Quinolines; Statistics, Nonparametric; Sulfides | 2002 |
Effects of montelukast on physical performance and exercise economy in adult asthmatics with exercise-induced bronchoconstriction.
Topics: Acetates; Adult; Analysis of Variance; Asthma, Exercise-Induced; Bronchial Provocation Tests; Bronchoconstriction; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Exercise Tolerance; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Pulmonary Gas Exchange; Quinolines; Respiration; Spirometry; Statistics, Nonparametric; Sulfides | 2002 |
The leukotriene receptor antagonist montelukast in the treatment of chronic idiopathic urticaria: a single-blind, placebo-controlled, crossover clinical study.
Topics: Acetates; Adult; Chronic Disease; Cross-Over Studies; Cyclopropanes; Female; Histamine H1 Antagonists; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Single-Blind Method; Sulfides; Urticaria | 2002 |
Protection against exercise-induced bronchoconstriction by montelukast in aspirin-sensitive and aspirin-tolerant patients with asthma.
Topics: Acetates; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma, Exercise-Induced; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Hypersensitivity; Exercise Test; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Leukotriene E4; Lung; Male; Middle Aged; Quinolines; Sulfides | 2002 |
Effect of montelukast added to inhaled corticosteroids on fractional exhaled nitric oxide in asthmatic children.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adolescent; Androstadienes; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Breath Tests; Budesonide; Child; Cyclopropanes; Drug Therapy, Combination; Female; Fluticasone; Forced Expiratory Volume; Humans; Male; Maximal Midexpiratory Flow Rate; Nitric Oxide; Prospective Studies; Quinolines; Single-Blind Method; Sulfides | 2002 |
Efficacy and tolerability of montelukast as a therapeutic agent for severe atopic dermatitis in adults.
Topics: Acetates; Adolescent; Adult; Cyclopropanes; Dermatitis, Atopic; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2002 |
Cost-effectiveness comparison of salmeterol/fluticasone propionate versus montelukast in the treatment of adults with persistent asthma.
Topics: Acetates; Adolescent; Adult; Aged; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Chronic Disease; Cost-Benefit Analysis; Cyclopropanes; Double-Blind Method; Drug Combinations; Female; Fluticasone; Humans; Male; Middle Aged; Quinolines; Salmeterol Xinafoate; Sulfides | 2002 |
Effects of montelukast and budesonide on airway responses and airway inflammation in asthma.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Anti-Inflammatory Agents; Asthma; Budesonide; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Humans; Inflammation; Leukotriene Antagonists; Prospective Studies; Quinolines; Respiratory Hypersensitivity; Respiratory System; Sulfides | 2002 |
A randomized trial of montelukast in respiratory syncytial virus postbronchiolitis.
Topics: Acetates; Bronchiolitis, Viral; Cyclopropanes; Double-Blind Method; Female; Humans; Infant; Leukotriene Antagonists; Male; Quinolines; Respiratory Syncytial Virus Infections; Sulfides | 2003 |
Montelukast versus fluticasone: effects on lung function, airway responsiveness and inflammation in moderate asthma.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Airway Resistance; Analysis of Variance; Androstadienes; Asthma; Bronchial Hyperreactivity; Cross-Over Studies; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Fluticasone; Follow-Up Studies; Humans; Male; Middle Aged; Nitric Oxide; Probability; Quinolines; Reference Values; Respiratory Function Tests; Severity of Illness Index; Sputum; Sulfides; Treatment Outcome | 2002 |
Dose reduction of inhaled corticosteroids under concomitant medication with montelukast in patients with asthma.
Topics: Acetates; Administration, Inhalation; Adult; Albuterol; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Beclomethasone; Breath Tests; Bronchial Provocation Tests; Bronchodilator Agents; Cyclopropanes; Drug Therapy, Combination; Female; Forced Expiratory Volume; Glucocorticoids; Humans; Leukotriene Antagonists; Male; Nitric Oxide; Peak Expiratory Flow Rate; Quinolines; Sputum; Sulfides | 2002 |
A randomized controlled trial of intravenous montelukast in acute asthma.
Topics: Acetates; Acute Disease; Adolescent; Adrenergic beta-Agonists; Adult; Albuterol; Analysis of Variance; Asthma; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Injections, Intravenous; Leukotriene Antagonists; Male; Middle Aged; Pilot Projects; Quinolines; Regression Analysis; Sulfides | 2003 |
Effects of montelukast on surrogate inflammatory markers in corticosteroid-treated patients with asthma.
Topics: Acetates; Adenosine Monophosphate; Adolescent; Adult; Aged; Albuterol; Androstadienes; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Biomarkers; Bronchial Provocation Tests; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Fluticasone; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Salmeterol Xinafoate; Severity of Illness Index; Sulfides; Treatment Outcome | 2003 |
Effects of montelukast and beclomethasone on airway function and asthma control.
Topics: Acetates; Adolescent; Adult; Aged; Asthma; Beclomethasone; Cyclopropanes; Double-Blind Method; Forced Expiratory Volume; Humans; Middle Aged; Quinolines; Sulfides | 2002 |
Effect of the addition of montelukast to inhaled fluticasone propionate on airway inflammation.
Topics: Acetates; Administration, Inhalation; Administration, Topical; Adult; Androstadienes; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Biopsy; Bronchi; Bronchodilator Agents; Cross-Over Studies; Cyclopropanes; Data Interpretation, Statistical; Double-Blind Method; Drug Therapy, Combination; Female; Fluticasone; Forced Expiratory Volume; Glucocorticoids; Humans; Immunohistochemistry; Inflammation; Interferon-gamma; Interleukin-4; Leukotriene Antagonists; Male; Middle Aged; Placebos; Quinolines; Sulfides; Time Factors | 2003 |
Time efficacy of a single dose of montelukast on exercise-induced asthma in children.
Topics: Acetates; Adolescent; Asthma, Exercise-Induced; Child; Child Welfare; Cross-Over Studies; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Exercise Test; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides; Time Factors; Treatment Outcome | 2002 |
Anti-inflammatory effects of montelukast in mild cystic fibrosis.
Topics: Acetates; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Child; Cross-Over Studies; Cyclopropanes; Cystic Fibrosis; Double-Blind Method; Eosinophil Granule Proteins; Eosinophilia; Humans; Inflammation; Interleukin-8; Leukocyte Count; Leukotriene Antagonists; Membrane Proteins; Pilot Projects; Quinolines; Receptors, Leukotriene; Respiratory Function Tests; Ribonucleases; Sulfides; Treatment Outcome | 2002 |
Clinical and genetic features underlying the response of patients with bronchial asthma to treatment with a leukotriene receptor antagonist.
Topics: Acetates; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclopropanes; Eosinophils; Female; Humans; Leukotriene Antagonists; Leukotriene C4; Lung; Male; Middle Aged; Peak Expiratory Flow Rate; Quinolines; Single-Blind Method; Statistics, Nonparametric; Sulfides | 2002 |
Distribution of therapeutic response in asthma control between oral montelukast and inhaled beclomethasone.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Aged; Anti-Asthmatic Agents; Asthma; Beclomethasone; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Quinolines; Spirometry; Sulfides; Time Factors | 2003 |
Exercise-induced bronchoconstriction in children: montelukast attenuates the immediate-phase and late-phase responses.
Topics: Acetates; Administration, Oral; Adolescent; Anti-Asthmatic Agents; Asthma; Bronchoconstriction; Child; Cross-Over Studies; Cyclopropanes; Exercise; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2003 |
Randomized controlled trial evaluating the clinical benefit of montelukast for treating spring seasonal allergic rhinitis.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Quality of Life; Quinolines; Rhinitis, Allergic, Seasonal; Severity of Illness Index; Sulfides; Treatment Outcome | 2003 |
Effect of montelukast added to inhaled budesonide on control of mild to moderate asthma.
Topics: Acetates; Administration, Inhalation; Adult; Aged; Analysis of Variance; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Budesonide; Cyclopropanes; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Quality of Life; Quinolines; Sulfides; Treatment Outcome | 2003 |
Randomised controlled trial of montelukast plus inhaled budesonide versus double dose inhaled budesonide in adult patients with asthma.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Aged; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Budesonide; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Quinolines; Single-Blind Method; Sulfides; Treatment Outcome | 2003 |
The salmeterol/fluticasone combination is more effective than fluticasone plus oral montelukast in asthma.
Topics: Acetates; Administration, Oral; Adolescent; Adult; Aged; Albuterol; Androstadienes; Asthma; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Fluticasone; Forced Expiratory Volume; Humans; Male; Middle Aged; Peak Expiratory Flow Rate; Quinolines; Salmeterol Xinafoate; Sulfides; Treatment Outcome | 2003 |
Comparison of montelukast and budesonide on bronchial reactivity in subjects with mild-moderate persistent asthma.
Topics: Acetates; Adult; Analysis of Variance; Anti-Asthmatic Agents; Asthma; Bronchi; Bronchial Provocation Tests; Budesonide; Cyclopropanes; Female; Humans; Male; Quinolines; Sulfides; Treatment Outcome | 2003 |
Response to montelukast among subgroups of children aged 2 to 14 years with asthma.
Topics: Acetates; Adolescent; Asthma; Child; Child, Preschool; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2003 |
Inhibitory effect of a leukotriene receptor antagonist (montelukast) on neurokinin A-induced bronchoconstriction.
Topics: Acetates; Adult; Bronchoconstriction; Cross-Over Studies; Cyclopropanes; Cysteine; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Leukotriene D4; Leukotrienes; Male; Methacholine Chloride; Neurokinin A; Quinolines; Sulfides | 2003 |
Effects of oral montelukast on airway function in acute asthma.
Topics: Acetates; Acute Disease; Administration, Oral; Aged; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Leukotriene Antagonists; Male; Middle Aged; Peak Expiratory Flow Rate; Prednisolone; Quinolines; Single-Blind Method; Sulfides | 2003 |
A randomized controlled trial on the effect of montelukast on sputum eosinophil cationic protein in children with corticosteroid-dependent asthma.
Topics: Acetates; Adolescent; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Blood Proteins; Budesonide; Child; Cyclopropanes; Drug Therapy, Combination; Eosinophil Granule Proteins; Eosinophils; Female; Humans; Male; Quinolines; Ribonucleases; Sputum; Sulfides; Treatment Outcome | 2003 |
Comparative effects of desloratadine versus montelukast on asthma symptoms and use of beta 2-agonists in patients with seasonal allergic rhinitis and asthma.
Topics: Acetates; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Double-Blind Method; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Middle Aged; Pulmonary Ventilation; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides; Treatment Outcome | 2003 |
Montelukast, a leukotriene receptor antagonist, in vernal keratoconjunctivitis associated with asthma.
Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Conjunctivitis, Allergic; Cyclopropanes; Enzyme-Linked Immunosorbent Assay; Female; Humans; Leukotriene Antagonists; Leukotriene B4; Leukotriene E4; Male; Ophthalmic Solutions; Peak Expiratory Flow Rate; Pilot Projects; Quinolines; Sulfides; Tears | 2003 |
Fluticasone nasal spray and the combination of loratadine and montelukast in seasonal allergic rhinitis.
Topics: Acetates; Adult; Androstadienes; Anti-Inflammatory Agents; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Fluticasone; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides | 2003 |
Fluticasone propionate aqueous nasal spray provided significantly greater improvement in daytime and nighttime nasal symptoms of seasonal allergic rhinitis compared with montelukast.
Topics: Acetates; Administration, Intranasal; Administration, Oral; Adult; Androstadienes; Anti-Allergic Agents; Cyclopropanes; Female; Fluticasone; Humans; Leukotriene Antagonists; Loratadine; Male; Nasal Obstruction; Pruritus; Quinolines; Rhinitis, Allergic, Seasonal; Sneezing; Sulfides | 2003 |
"Real-world" effectiveness of daily controller medicine in children with mild persistent asthma.
Topics: Acetates; Administration, Intranasal; Administration, Oral; Adolescent; Adrenergic beta-Agonists; Androstadienes; Anti-Bacterial Agents; Asthma; Bronchodilator Agents; Child; Cyclopropanes; Emergency Medical Services; Female; Fluticasone; Humans; Leukotriene Antagonists; Male; Patient Compliance; Peak Expiratory Flow Rate; Pilot Projects; Prednisolone; Prospective Studies; Quinolines; Sulfides | 2003 |
The effect of montelukast on allergen-induced cutaneous responses in house dust mite allergic children.
Topics: Acetates; Adolescent; Allergens; Child; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Humans; Hypersensitivity, Immediate; Leukotriene Antagonists; Male; Pyroglyphidae; Quinolines; Sulfides; Treatment Outcome | 2003 |
Effects of mediator antagonism on mannitol and adenosine monophosphate challenges.
Topics: Acetates; Adenosine Monophosphate; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Leukotriene Antagonists; Loratadine; Male; Mannitol; Middle Aged; Quinolines; Sulfides; Time Factors | 2003 |
Montelukast as an adjuvant to mainstay therapies in patients with seasonal allergic rhinitis.
Topics: Acetates; Adjuvants, Immunologic; Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Cyclopropanes; Drug Therapy, Combination; Female; Histamine H1 Antagonists; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Mometasone Furoate; Patient Satisfaction; Pregnadienediols; Prospective Studies; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides | 2003 |
A proof of concept study to evaluate putative benefits of montelukast in moderate persistent asthmatics.
Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Chronic Disease; Cyclopropanes; Double-Blind Method; Drug Evaluation; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Peak Expiratory Flow Rate; Quinolines; Sulfides; Treatment Outcome | 2003 |
The effects of histamine and leukotriene receptor antagonism on nasal mannitol challenge in allergic rhinitis.
Topics: Acetates; Adult; Cross-Over Studies; Cyclopropanes; Diuretics, Osmotic; Double-Blind Method; Histamine H1 Antagonists, Non-Sedating; Humans; Inspiratory Capacity; Loratadine; Mannitol; Middle Aged; Nasal Provocation Tests; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides | 2003 |
Efficacy of montelukast, in combination with loratadine, in the treatment of delayed pressure urticaria.
Topics: Acetates; Adult; Aged; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Histamine H1 Antagonists; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Quinolines; Sulfides; Urticaria | 2003 |
Add-on therapy with montelukast or formoterol in patients with the glycine-16 beta2-receptor genotype.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Down-Regulation; Drug Therapy, Combination; Ethanolamines; Forced Expiratory Volume; Formoterol Fumarate; Humans; Peak Expiratory Flow Rate; Quinolines; Receptors, Adrenergic, beta-2; Sulfides | 2003 |
Short-term effect of the addition of leukotriene receptor antagonists to the current therapy in severe asthmatics.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Female; Humans; Indoles; Leukotriene Antagonists; Lung Volume Measurements; Male; Middle Aged; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome | 2003 |
[The effectiveness of leukotriene antagonists in the treatment of aspirin-intolerant asthmatic patients].
Topics: Acetates; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bleeding Time; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Quality of Life; Quinolines; Rhinitis; Severity of Illness Index; Spirometry; Sulfides; Surveys and Questionnaires | 2003 |
Montelukast improves asthma control in asthmatic children maintained on inhaled corticosteroids.
Topics: Acetates; Administration, Intranasal; Adolescent; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Double-Blind Method; Drug Synergism; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Pilot Projects; Quinolines; Sulfides | 2003 |
[Montelukast-free interval before inhalational bronchial allergen provocation].
Topics: Acetates; Adult; Allergens; Anti-Asthmatic Agents; Bronchial Provocation Tests; Cyclopropanes; Drug Administration Schedule; Female; Humans; Male; Quinolines; Reproducibility of Results; Sulfides; Time Factors | 2003 |
The effects of montelukast on intradermal wheal and flare.
Topics: Acetates; Adolescent; Adult; Aged; Anti-Allergic Agents; Candida albicans; Cyclopropanes; Double-Blind Method; Female; Follow-Up Studies; Histamine; Humans; Hypersensitivity, Immediate; Injections, Intradermal; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Prospective Studies; Quinolines; Rhinitis, Allergic, Seasonal; Skin Tests; Sulfides | 2003 |
Effect of montelukast on time-course of exhaled nitric oxide in asthma: influence of LTC4 synthase A(-444)C polymorphism.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Breath Tests; Child; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Glutathione Transferase; Humans; Male; Nitric Oxide; Pharmacogenetics; Polymorphism, Genetic; Quinolines; Spirometry; Sulfides; Time Factors | 2003 |
Evaluation of parental preference for the treatment of asthmatic children aged 6 to 11 years with oral montelukast or inhaled cromolyn: a randomized, open-label, crossover study.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Albuterol; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Child; Cromolyn Sodium; Cross-Over Studies; Cyclopropanes; Female; Humans; Male; Parents; Patient Compliance; Patient Satisfaction; Quinolines; Sulfides | 2003 |
Comparisons of the complementary effect on exhaled nitric oxide of salmeterol vs montelukast in asthmatic children taking regular inhaled budesonide.
Topics: Acetates; Administration, Inhalation; Adolescent; Albuterol; Asthma; Breath Tests; Bronchodilator Agents; Budesonide; Child; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Humans; Nitric Oxide; Quinolines; Salmeterol Xinafoate; Sulfides | 2003 |
Effect of montelukast on exhaled nitric oxide and nonvolatile markers of inflammation in mild asthma.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Biomarkers; Breath Tests; Cross-Over Studies; Cyclopropanes; Cysteine; Double-Blind Method; Exhalation; Female; Forced Expiratory Volume; Humans; Hydrogen Peroxide; Inflammation Mediators; Leukotrienes; Male; Nitric Oxide; Peak Expiratory Flow Rate; Pneumonia; Quinolines; Severity of Illness Index; Sulfides | 2003 |
Montelukast and fluticasone compared with salmeterol and fluticasone in protecting against asthma exacerbation in adults: one year, double blind, randomised, comparative trial.
Topics: Acetates; Adolescent; Adult; Aged; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Fluticasone; Forced Expiratory Volume; Humans; Middle Aged; Quinolines; Salmeterol Xinafoate; Sulfides; Treatment Outcome | 2003 |
Montelukast improves symptoms of seasonal allergic rhinitis over a 4-week treatment period.
Topics: Acetates; Adolescent; Adult; Aged; Anti-Allergic Agents; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides; Treatment Outcome | 2003 |
The effect of montelukast on bronchial provocation tests and exhaled nitric oxide levels in asthmatic patients.
Topics: Acetates; Adenosine; Administration, Oral; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Bronchial Provocation Tests; Bronchoconstrictor Agents; Child; Cyclopropanes; Exercise; Female; Humans; Male; Methacholine Chloride; Middle Aged; Nitric Oxide; Quinolines; Spirometry; Sulfides; Treatment Outcome; Vasodilator Agents | 2003 |
No effect of montelukast on asthma-like symptoms in elite ice hockey players.
Topics: Acetates; Administration, Oral; Adult; Analysis of Variance; Asthma, Exercise-Induced; Bronchial Hyperreactivity; Cross-Over Studies; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Finland; Hockey; Humans; Leukotriene Antagonists; Male; Probability; Quinolines; Reference Values; Risk Assessment; Severity of Illness Index; Spirometry; Statistics, Nonparametric; Sulfides; Treatment Failure | 2004 |
Montelukast attenuates the airway response to hypertonic saline in moderate-to-severe COPD.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Aged; Airway Obstruction; Albuterol; Bronchodilator Agents; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Metered Dose Inhalers; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quinolines; Recovery of Function; Respiratory Function Tests; Saline Solution, Hypertonic; Solutions; Sulfides; Treatment Outcome | 2003 |
Comparative efficacy of once-daily therapy with inhaled corticosteroid, leukotriene antagonist or sustained-release theophylline in patients with mild persistent asthma.
Topics: Acetates; Administration, Inhalation; Adrenergic beta-2 Receptor Antagonists; Adult; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Budesonide; Cyclopropanes; Delayed-Action Preparations; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Middle Aged; Peak Expiratory Flow Rate; Quinolines; Sulfides; Theophylline; Treatment Outcome | 2003 |
[A fixed combination of fluticasone and salmeterol permits better control of asthma than a beclomethasone dipropionate and montelukast combination].
Topics: Acetates; Administration, Inhalation; Adult; Aerosols; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Beclomethasone; Bronchodilator Agents; Cyclopropanes; Drug Combinations; Female; Fluticasone; Humans; Leukotriene Antagonists; Male; Middle Aged; Peak Expiratory Flow Rate; Powders; Prospective Studies; Quinolines; Salmeterol Xinafoate; Sulfides; Treatment Outcome | 2003 |
Comparison of the combinations of fexofenadine-pseudoephedrine and loratadine-montelukast in the treatment of seasonal allergic rhinitis.
Topics: Acetates; Adolescent; Adult; Ambrosia; Anti-Allergic Agents; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Ephedrine; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Quality of Life; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides; Surveys and Questionnaires; Terfenadine; Treatment Outcome; Vasoconstrictor Agents | 2004 |
Montelukast plus cetirizine in the prophylactic treatment of seasonal allergic rhinitis: influence on clinical symptoms and nasal allergic inflammation.
Topics: Acetates; Adolescent; Adult; Cetirizine; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Eosinophil Cationic Protein; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Quinolines; Rhinitis, Allergic, Seasonal; Serine Endopeptidases; Sulfides; Tryptases | 2004 |
Montelukast 10 mg improves nasal function and nasal response to aspirin in ASA-sensitive asthmatics: a controlled study vs placebo.
Topics: Acetates; Adult; Airway Resistance; Aspirin; Asthma; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Nasal Provocation Tests; Nose; Quinolines; Sulfides | 2004 |
Randomized placebo-controlled trial comparing fluticasone aqueous nasal spray in mono-therapy, fluticasone plus cetirizine, fluticasone plus montelukast and cetirizine plus montelukast for seasonal allergic rhinitis.
Topics: Acetates; Administration, Intranasal; Adolescent; Adult; Analysis of Variance; Androstadienes; Blood Proteins; Cetirizine; Child; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Eosinophil Granule Proteins; Female; Fluticasone; Glucocorticoids; Histamine H1 Antagonists; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Rhinitis, Allergic, Seasonal; Ribonucleases; Sulfides | 2004 |
The effects of butterbur on the histamine and allergen cutaneous response.
Topics: Acetates; Adult; Anti-Inflammatory Agents; Cross-Over Studies; Cyclopropanes; Dermatitis, Atopic; Double-Blind Method; Female; Histamine; Humans; Male; Petasites; Phytotherapy; Quinolines; Skin Tests; Sulfides; Terfenadine | 2004 |
Effect of montelukast and fluticasone propionate on airway mucosal blood flow in asthma.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Aged; Androstadienes; Asthma; Blood Flow Velocity; Bronchi; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluticasone; Follow-Up Studies; Humans; Male; Middle Aged; Mucous Membrane; Multivariate Analysis; Probability; Pulmonary Circulation; Quinolines; Severity of Illness Index; Spirometry; Sulfides; Treatment Outcome | 2004 |
Montelukast for treating fall allergic rhinitis: effect of pollen exposure in 3 studies.
Topics: Acetates; Adult; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Pollen; Quinolines; Rhinitis, Allergic, Seasonal; Seasons; Sulfides | 2004 |
Antihistamines added to an antileukotriene in treating seasonal allergic rhinitis: histamine and leukotriene antagonism.
Topics: Acetates; Adolescent; Adult; Asthma; Cetirizine; Cyclopropanes; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Forced Expiratory Volume; Histamine H1 Antagonists; Humans; Interleukin-15; Interleukin-18; Leukocyte Count; Leukotriene Antagonists; Male; Nasal Mucosa; Pruritus; Quinolines; Rhinitis, Allergic, Seasonal; Sneezing; Sulfides; Therapeutic Irrigation | 2004 |
Clinical efficacy and pharmacokinetics of montelukast in dyspeptic children with duodenal eosinophilia.
Topics: Acetates; Adolescent; Child; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Duodenal Diseases; Dyspepsia; Eosinophilia; Female; Humans; Intestinal Mucosa; Leukotriene Antagonists; Male; Pain; Quinolines; Sulfides; Treatment Outcome | 2004 |
Repeated dosing effects of mediator antagonists in inhaled corticosteroid-treated atopic asthmatic patients.
Topics: Acetates; Adenosine Monophosphate; Administration, Inhalation; Adrenal Cortex Hormones; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Peak Expiratory Flow Rate; Quinolines; Respiratory Hypersensitivity; Sulfides; Terfenadine; Treatment Outcome | 2004 |
Pharmacokinetics of montelukast in asthmatic patients 6 to 24 months old.
Topics: Acetates; Administration, Oral; Area Under Curve; Asthma; Blood Urea Nitrogen; Chemistry, Pharmaceutical; Child, Preschool; Cyclopropanes; Diarrhea; Half-Life; Humans; Infant; Male; Mastication; Quinolines; Receptors, Leukotriene B4; Sulfides; Tablets | 2004 |
The use of the leukotriene receptor antagonist montelukast (Singulair) in the management of dysmenorrhea in adolescents.
Topics: Acetates; Adolescent; Adult; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Dysmenorrhea; Female; Humans; Leukotriene Antagonists; Menstrual Cycle; Quinolines; Sulfides; Treatment Outcome | 2004 |
Effects of single or combined histamine H1-receptor and leukotriene CysLT1-receptor antagonism on nasal adenosine monophosphate challenge in persistent allergic rhinitis.
Topics: Acetates; Adult; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Combinations; Female; Humans; Leukotriene Antagonists; Male; Nucleotidases; Quinolines; Receptors, Histamine H1; Rhinitis, Allergic, Perennial; Sulfides; Terfenadine; Treatment Outcome | 2004 |
Cysteinyl leukotriene blockade does not prevent acute mountain sickness.
Topics: Acetates; Administration, Oral; Adult; Altitude Sickness; Analysis of Variance; Chromatography, High Pressure Liquid; Cross-Over Studies; Cyclopropanes; Cysteine; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female; Humans; Leukotriene Antagonists; Leukotrienes; Male; Prevalence; Quinolines; Severity of Illness Index; Statistics, Nonparametric; Sulfides; Treatment Outcome | 2004 |
Addition of montelukast versus double dose of inhaled budesonide in moderate persistent asthma.
Topics: Acetates; Adult; Asthma; Bronchodilator Agents; Budesonide; Cyclopropanes; Drug Therapy, Combination; Female; Humans; Leukotriene Antagonists; Male; Quinolines; Spirometry; Sulfides | 2004 |
Montelukast for migraine prophylaxis: a randomized, double-blind, placebo-controlled study.
Topics: Acetates; Adult; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Migraine Disorders; Quinolines; Sulfides; Treatment Outcome | 2004 |
Effect of cysteinyl leukotriene receptor antagonist on CD11b and CD23 expression in asthmatic children.
Topics: Acetates; Asthma; CD11b Antigen; Child; Cyclopropanes; Eosinophils; Female; Flow Cytometry; Forced Expiratory Volume; Humans; Immunoglobulin E; Leukocyte Count; Leukotriene Antagonists; Lung; Lymphocyte Count; Male; Membrane Proteins; Peak Expiratory Flow Rate; Quinolines; Receptors, IgE; Receptors, Leukotriene; Statistics, Nonparametric; Sulfides; T-Lymphocytes | 2004 |
A clinical trial of the efficacy and safety of montelukast as monotherapy in patients with chronic stable bronchial asthma.
Topics: Acetates; Adult; Aged; Anti-Asthmatic Agents; Asthma; Chronic Disease; Cyclopropanes; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Middle Aged; Peak Expiratory Flow Rate; Prospective Studies; Quinolines; Sulfides; Treatment Outcome | 2004 |
Addition of montelukast or salmeterol to fluticasone for protection against asthma attacks: a randomized, double-blind, multicenter study.
Topics: Acetates; Adolescent; Adult; Aged; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Fluticasone; Forced Expiratory Volume; History, 16th Century; Humans; Male; Middle Aged; Quinolines; Salmeterol Xinafoate; Sulfides; Treatment Outcome | 2004 |
Comparative effect of triamcinolone, nedocromil and montelukast on asthma control in children: A randomized pragmatic study.
Topics: Acetates; Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Child; Cyclopropanes; Eosinophils; Female; Humans; Male; Nedocromil; Quinolines; Respiratory Function Tests; Sulfides; Triamcinolone | 2004 |
Montelukast protects against nasal lysine-aspirin challenge in patients with aspirin-induced asthma.
Topics: Acetates; Administration, Inhalation; Adult; Aspirin; Asthma; Confidence Intervals; Cross-Over Studies; Cyclopropanes; Cysteine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Leukotrienes; Lysine; Male; Middle Aged; Nasal Provocation Tests; Peak Expiratory Flow Rate; Quinolines; Reference Values; Reproducibility of Results; Spirometry; Sulfides | 2004 |
Variability of symptoms in mild persistent asthma: baseline data from the MIAMI study.
Topics: Acetates; Administration, Oral; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Albuterol; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Cohort Studies; Cyclopropanes; Double-Blind Method; Exercise; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Middle Aged; Patient Acceptance of Health Care; Quinolines; Severity of Illness Index; Sulfides | 2004 |
Effect of montelukast compared with inhaled fluticasone on airway inflammation.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adult; Androstadienes; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Cyclopropanes; Double-Blind Method; Eosinophil Cationic Protein; Female; Fluticasone; Humans; Immunohistochemistry; Interleukin-5; Leukotriene Antagonists; Lung; Male; Mast Cells; Middle Aged; Quinolines; Receptors, Interleukin-2; Sulfides; T-Lymphocytes | 2004 |
Desloratadine in combination with montelukast in the treatment of chronic urticaria: a randomized, double-blind, placebo-controlled study.
Topics: Acetates; Administration, Oral; Adolescent; Adult; Aged; Chronic Disease; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Pruritus; Quality of Life; Quinolines; Severity of Illness Index; Sulfides; Treatment Outcome; Urticaria | 2004 |
Randomized placebo-controlled trial comparing desloratadine and montelukast in monotherapy and desloratadine plus montelukast in combined therapy for chronic idiopathic urticaria.
Topics: Acetates; Adolescent; Adult; Aged; Chronic Disease; Cyclopropanes; Double-Blind Method; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Quinolines; Sulfides; Treatment Outcome; Urticaria | 2004 |
A double-blind placebo-controlled trial of a leukotriene receptor antagonist in chronic pancreatitis in humans.
Topics: Acetates; Adult; Aged; C-Reactive Protein; Chronic Disease; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Pain Measurement; Pancreatitis; Quinolines; Sulfides; Treatment Failure | 2004 |
Montelukast - evaluation in 6 to 14 years old children with persistent asthma - pediatric montelukast study group.
Topics: Acetates; Administration, Oral; Adolescent; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Drug Administration Schedule; Female; Humans; Male; Prospective Studies; Quinolines; Sulfides | 2004 |
The effect of montelukast on rhinitis symptoms in patients with asthma and seasonal allergic rhinitis.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Double-Blind Method; Female; Humans; Male; Middle Aged; Quinolines; Rhinitis, Allergic, Seasonal; Single-Blind Method; Sulfides; Treatment Outcome | 2004 |
Montelukast in asthmatic patients 6 years-14 years old with an FEV1 > 75%.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Placebos; Quinolines; Severity of Illness Index; Sulfides; Treatment Outcome | 2004 |
Effectiveness of montelukast in the treatment of cough variant asthma.
Topics: Acetates; Adrenergic beta-Agonists; Adult; Aged; Anti-Asthmatic Agents; Antitussive Agents; Asthma; Bronchial Provocation Tests; Cough; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Methacholine Chloride; Middle Aged; Monitoring, Ambulatory; Pilot Projects; Quinolines; Severity of Illness Index; Sulfides; Treatment Outcome | 2004 |
Montelukast and airway remodeling in children with chronic persistent asthma: an open study.
Topics: Acetates; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Child; Chronic Disease; Cyclopropanes; Drug Therapy, Combination; Fluticasone; Follow-Up Studies; Humans; Lung; Quinolines; Respiratory Function Tests; Salmeterol Xinafoate; Sulfides | 2004 |
Effects of montelukast and salmeterol on physical performance and exercise economy in adult asthmatics with exercise-induced bronchoconstriction.
Topics: Acetates; Adolescent; Adrenergic beta-Agonists; Adult; Albuterol; Anti-Asthmatic Agents; Asthma, Exercise-Induced; Bronchoconstriction; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Lactates; Male; Pulmonary Gas Exchange; Quinolines; Salmeterol Xinafoate; Sulfides | 2004 |
Montelukast has no ergogenic effect on cycle ergometry in cold temperature.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Cold Temperature; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Exercise; Exercise Test; Hockey; Humans; Lung; Male; Quinolines; Respiratory Function Tests; Sulfides; Task Performance and Analysis | 2004 |
A comparison of the effects of oral montelukast and inhaled salmeterol on response to rescue bronchodilation after challenge.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adolescent; Adrenergic beta-Agonists; Adult; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma, Exercise-Induced; Bronchodilator Agents; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Fluticasone; Forced Expiratory Volume; Humans; Middle Aged; Quinolines; Salmeterol Xinafoate; Sulfides; Treatment Outcome | 2004 |
Montelukast reduces asthma exacerbations in 2- to 5-year-old children with intermittent asthma.
Topics: Acetates; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Asthmatic Agents; Asthma; Child, Preschool; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Eosinophils; Female; Humans; Male; Quinolines; Respiratory Tract Infections; Severity of Illness Index; Sulfides; Time Factors; Treatment Outcome | 2005 |
Protective effect of montelukast on lower and upper respiratory tract responses to short-term cat allergen exposure.
Topics: Acetates; Adolescent; Adult; Allergens; Animals; Area Under Curve; Asthma; Cats; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Hypersensitivity; Male; Middle Aged; Quinolines; Respiratory System; Rhinitis, Allergic, Seasonal; Sulfides | 2004 |
Differential effects of fluticasone and montelukast on allergen-induced asthma.
Topics: Acetates; Adult; Allergens; Androstadienes; Asthma; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Eosinophils; Female; Fluticasone; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Methacholine Chloride; Quinolines; Sputum; Sulfides; Time Factors | 2005 |
Prolonged effect of montelukast in asthmatic children with exercise-induced bronchoconstriction.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Bronchoconstriction; Child; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Exercise Test; Female; Forced Expiratory Volume; Humans; Male; Quinolines; Spirometry; Sulfides; Time Factors; Treatment Outcome | 2005 |
The effect of montelukast versus usual care on health care resource utilization in children aged 2 to 5 years with asthma.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Child, Preschool; Cromolyn Sodium; Cyclopropanes; Double-Blind Method; Female; Health Resources; Humans; Male; Quinolines; Sulfides | 2004 |
Failure of montelukast to reduce sputum eosinophilia in high-dose corticosteroid-dependent asthma.
Topics: Acetates; Adult; Aged; Analysis of Variance; Asthma; Cross-Over Studies; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Eosinophilia; Eosinophils; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Prednisone; Probability; Quinolines; Reference Values; Respiratory Function Tests; Risk Assessment; Severity of Illness Index; Sputum; Sulfides; Treatment Failure | 2005 |
Effect of budesonide and montelukast in asthmatic children exposed to relevant allergens.
Topics: Acetates; Allergens; Anti-Asthmatic Agents; Antigens, Dermatophagoides; Asthma; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Bronchodilator Agents; Budesonide; Child; Cyclopropanes; Eosinophils; Exhalation; Female; Humans; Lung; Male; Methacholine Chloride; Nitric Oxide; Quinolines; Respiratory Function Tests; Sputum; Sulfides | 2005 |
Steroid naive eosinophilic asthma: anti-inflammatory effects of fluticasone and montelukast.
Topics: Acetates; Adult; Androstadienes; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Double-Blind Method; Eosinophils; Female; Fluticasone; Humans; Leukotriene Antagonists; Male; Patient Compliance; Pulmonary Eosinophilia; Quinolines; Sputum; Sulfides; Treatment Outcome | 2005 |
The effect of montelukast on lung function and exhaled nitric oxide in infants with early childhood asthma.
Topics: Acetates; Administration, Inhalation; Analysis of Variance; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Infant; Male; Nitric Oxide; Prospective Studies; Quinolines; Statistics, Nonparametric; Sulfides; Treatment Outcome | 2005 |
Characterization of within-subject responses to fluticasone and montelukast in childhood asthma.
Topics: Acetates; Administration, Inhalation; Adolescent; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Child; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Eosinophil Cationic Protein; Eosinophils; Exhalation; Female; Fluticasone; Forced Expiratory Volume; Humans; Immunoglobulin E; Leukocyte Count; Male; Nitric Oxide; Predictive Value of Tests; Quinolines; Sulfides; Vital Capacity | 2005 |
[Effect of montelukast on lung function and clinical symptoms in patients with cystic fibrosis].
Topics: Acetates; Adolescent; Adult; Child; Cross-Over Studies; Cyclopropanes; Cystic Fibrosis; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Plethysmography, Whole Body; Quinolines; Spirometry; Sulfides; Treatment Outcome | 2004 |
Short-term effects of montelukast in stable patients with moderate to severe COPD.
Topics: Acetates; Aged; Cyclopropanes; Dyspnea; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Neutrophils; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Quality of Life; Quinolines; Respiratory Function Tests; Single-Blind Method; Sputum; Sulfides | 2005 |
Bronchoconstriction provoked by exercise in a high-particulate-matter environment is attenuated by montelukast.
Topics: Acetates; Adolescent; Adult; Air Pollutants; Anti-Asthmatic Agents; Bronchoconstriction; Cyclopropanes; Double-Blind Method; Environmental Exposure; Exercise; Hockey; Humans; Male; Particle Size; Placebos; Quinolines; Spirometry; Sulfides; Treatment Outcome; Vehicle Emissions | 2005 |
Effects of montelukast on airway narrowing from eucapnic voluntary hyperventilation and cold air exercise.
Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Asthma, Exercise-Induced; Bronchoconstriction; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Exercise; Exercise Test; Female; Forced Expiratory Volume; Humans; Hyperventilation; Leukotriene Antagonists; Male; Quinolines; Sulfides; Temperature; Treatment Outcome; Vital Capacity | 2005 |
Montelukast protects against bradykinin-induced bronchospasm.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Bradykinin; Bronchial Provocation Tests; Bronchial Spasm; Cyclopropanes; Forced Expiratory Volume; Humans; Quinolines; Sulfides | 2005 |
[Clinical effects of montelukast sodium in treatment of allergic rhinetis in children].
Topics: Acetates; Child; Child, Preschool; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Quinolines; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Single-Blind Method; Sulfides | 2005 |
A population pharmacokinetic model for montelukast disposition in adults and children.
Topics: Acetates; Adolescent; Adult; Age Factors; Aged; Anti-Asthmatic Agents; Area Under Curve; Body Weight; Child; Cyclopropanes; Double-Blind Method; Humans; Injections, Intravenous; Middle Aged; Models, Biological; Quinolines; Sulfides | 2005 |
Leukotriene modifier therapy for mild sleep-disordered breathing in children.
Topics: Acetates; Administration, Oral; Case-Control Studies; Child; Child, Preschool; Cyclopropanes; Drug Administration Schedule; Female; Humans; Leukotriene Antagonists; Male; Polysomnography; Quinolines; Receptors, Leukotriene; Sleep Apnea Syndromes; Sulfides; Treatment Outcome | 2005 |
Brief case series: montelukast, at doses recommended for asthma treatment, reduces disease severity and increases soluble CD14 in children with atopic dermatitis.
Topics: Acetates; Administration, Oral; Adolescent; Child; Child, Preschool; Cyclopropanes; Dermatitis, Atopic; Female; Humans; Leukotriene Antagonists; Lipopolysaccharide Receptors; Male; Quinolines; Statistics, Nonparametric; Sulfides; Treatment Outcome | 2005 |
Short-term and long-term asthma control in patients with mild persistent asthma receiving montelukast or fluticasone: a randomized controlled trial.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Androstadienes; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Double-Blind Method; Fluticasone; Forced Expiratory Volume; Humans; Quinolines; Sulfides; Treatment Outcome | 2005 |
Role of leukotriene inhibitors in the postoperative management of nasal polyps.
Topics: Acetates; Adolescent; Adult; Aged; Anti-Asthmatic Agents; Beclomethasone; Chi-Square Distribution; Cyclopropanes; Double-Blind Method; Female; Glucocorticoids; Headache; Humans; Leukotriene Antagonists; Male; Middle Aged; Nasal Polyps; Olfaction Disorders; Postoperative Care; Postoperative Complications; Prospective Studies; Pruritus; Quinolines; Sneezing; Sulfides | 2005 |
The effect of montelukast and different doses of budesonide on IgE serum levels and clinical parameters in children with newly diagnosed asthma.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adolescent; Anti-Asthmatic Agents; Antigens, Dermatophagoides; Asthma; Budesonide; Child; Child, Preschool; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Immunoglobulin E; Male; Quinolines; Severity of Illness Index; Sulfides; Treatment Outcome | 2005 |
Discrepant clinical responses and blood chemokine profiles between two non-steroidal anti-inflammatory medications for children with mild persistent asthma.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Chemokine CCL17; Chemokine CCL22; Chemokines; Chemokines, CC; Child; Cyclopropanes; Double-Blind Method; Histamine H1 Antagonists; Humans; Ketotifen; Leukotriene Antagonists; Peak Expiratory Flow Rate; Quinolines; Respiratory Function Tests; Sulfides; Th2 Cells | 2005 |
Inflammatory basis of exercise-induced bronchoconstriction.
Topics: Acetates; Adolescent; Adult; Asthma; Bronchitis; Bronchoconstriction; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Exercise; Female; Forced Expiratory Volume; Histamine H1 Antagonists, Non-Sedating; Humans; Inflammation Mediators; Leukotriene Antagonists; Loratadine; Lung; Male; Middle Aged; Quinolines; Severity of Illness Index; Sulfides | 2005 |
Montelukast treatment of moderate to severe atopic dermatitis in adults: a randomized, double-blind, placebo-controlled trial.
Topics: Acetates; Adolescent; Adult; Age Factors; Aged; Cyclopropanes; Dermatitis, Atopic; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Prospective Studies; Quinolines; Severity of Illness Index; Sulfides | 2005 |
Safety, tolerability, and exploratory efficacy of montelukast in 6- to 24-month-old patients with asthma.
Topics: Acetates; Administration, Oral; Adrenergic beta-Agonists; Anti-Asthmatic Agents; Asthma; Child, Preschool; Cyclopropanes; Double-Blind Method; Female; Humans; Infant; Male; Placebos; Quinolines; Sulfides | 2005 |
Traditional and patient-centred outcomes with three classes of asthma medication.
Topics: Acetates; Adolescent; Adult; Aged; Androstadienes; Asthma; Cross-Over Studies; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Ethanolamines; Female; Fluticasone; Follow-Up Studies; Forced Expiratory Volume; Formoterol Fumarate; Humans; Linear Models; Male; Middle Aged; New South Wales; Patient Satisfaction; Patient-Centered Care; Probability; Quality of Life; Quinolines; Respiratory Function Tests; Severity of Illness Index; Single-Blind Method; Sulfides; Treatment Outcome | 2005 |
The effectiveness of montelukast for the treatment of anti-histamine-resistant chronic urticaria.
Topics: Acetates; Adolescent; Adult; Aged; Child; Child, Preschool; Chronic Disease; Cyclopropanes; Drug Resistance; Female; Histamine H1 Antagonists; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Sulfides; Urticaria | 2005 |
Montelukast, compared with fluticasone, for control of asthma among 6- to 14-year-old patients with mild asthma: the MOSAIC study.
Topics: Acetates; Administration, Inhalation; Adolescent; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Child; Cyclopropanes; Double-Blind Method; Female; Fluticasone; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2005 |
[The effect of antianaphylaxis drugs on specific IgE and eosinophil in serum of patients with allergic rhinitis].
Topics: Acetates; Adult; Cyclopropanes; Eosinophils; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Immunoglobulin E; Leukotriene Antagonists; Loratadine; Male; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides | 2005 |
Tapering dose of inhaled budesonide in subjects with mild-to-moderate persistent asthma treated with montelukast: a 16-week single-blind randomized study.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Budesonide; Cyclopropanes; Female; Humans; Male; Middle Aged; Quinolines; Respiratory Function Tests; Single-Blind Method; Sulfides; Time Factors | 2005 |
Leukotriene receptor antagonists are not as effective as intranasal corticosteroids for managing nighttime symptoms of allergic rhinitis.
Topics: Acetates; Administration, Intranasal; Androstadienes; Circadian Rhythm; Cyclopropanes; Double-Blind Method; Fluticasone; Humans; Leukotriene Antagonists; Quinolines; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sulfides | 2005 |
Comparative efficacy and safety of low-dose fluticasone propionate and montelukast in children with persistent asthma.
Topics: Acetates; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Child; Cyclopropanes; Double-Blind Method; Female; Fluticasone; Humans; Hydrocortisone; Male; Quinolines; Respiratory Function Tests; Severity of Illness Index; Sulfides; Treatment Outcome | 2005 |
Leukotriene D4-induced hypoxaemia in asthma is mediated by the cys-leukotriene1 receptor.
Topics: Acetates; Adult; Asthma; Bronchial Provocation Tests; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Humans; Hypoxia; Leukotriene Antagonists; Leukotriene D4; Male; Membrane Proteins; Quinolines; Receptors, Leukotriene; Severity of Illness Index; Sulfides; Ventilation-Perfusion Ratio | 2005 |
Determining economic feasibility of fluticasone propionate-salmeterol vs montelukast in the treatment of persistent asthma using a net benefit approach and cost-effectiveness acceptability curves.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Cost-Benefit Analysis; Cyclopropanes; Double-Blind Method; Drug Combinations; Drug Costs; Female; Fluticasone-Salmeterol Drug Combination; Humans; Leukotriene Antagonists; Male; Middle Aged; Prospective Studies; Quinolines; Respiratory Function Tests; Sulfides | 2005 |
Effect of combined montelukast and desloratadine on the early asthmatic response to inhaled allergen.
Topics: Acetates; Adult; Allergens; Anti-Asthmatic Agents; Asthma; Bronchial Provocation Tests; Cross-Over Studies; Cyclopropanes; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Loratadine; Male; Middle Aged; Quinolines; Sulfides; Time Factors | 2005 |
Fluticasone propionate nasal spray is superior to montelukast for allergic rhinitis while neither affects overall asthma control.
Topics: Acetates; Administration, Inhalation; Adult; Androstadienes; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Female; Fluticasone; Forced Expiratory Volume; Humans; Male; Patient Selection; Quinolines; Reproducibility of Results; Respiratory Distress Syndrome; Respiratory Function Tests; Rhinitis, Allergic, Perennial; Sleep Wake Disorders; Sulfides; Treatment Outcome; Wakefulness | 2005 |
Effect of montelukast on exhaled leukotrienes and quality of life in asthmatic patients.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Breath Tests; Cyclopropanes; Exhalation; Family Practice; Female; Forced Expiratory Volume; Humans; Leukotrienes; Male; Middle Aged; Quality of Life; Quinolines; Sulfides; Vital Capacity | 2005 |
Montelukast (Singulair) for perennial allergic rhinitis.
Topics: Acetates; Adult; Cross-Over Studies; Cyclopropanes; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Enzyme Inhibitors; Humans; Quinolines; Rhinitis, Allergic, Perennial; Sulfides | 2005 |
Effects of montelukast treatment on clinical and inflammatory variables in patients with cystic fibrosis.
Topics: Acetates; Adolescent; Airway Resistance; Anti-Asthmatic Agents; Child; Cough; Cross-Over Studies; Cyclopropanes; Cystic Fibrosis; Double-Blind Method; Eosinophil Cationic Protein; Female; Forced Expiratory Volume; Humans; Interleukin-10; Interleukin-8; Male; Peroxidase; Quinolines; Respiratory Sounds; Sputum; Sulfides; Treatment Outcome | 2005 |
Montelukast improves pulmonary function measured by impulse oscillometry in children with asthma (Mio study).
Topics: Acetates; Administration, Oral; Adolescent; Airway Resistance; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Oscillometry; Peak Expiratory Flow Rate; Quinolines; Sulfides; Treatment Outcome | 2006 |
Effects of montelukast on symptoms and eNO in children with mild to moderate asthma.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Breath Tests; Child; Cyclopropanes; Female; Humans; Male; Nitric Oxide; Peak Expiratory Flow Rate; Quinolines; Sulfides; Time Factors; Treatment Outcome | 2005 |
Effect of montelukast on basophil releasability in patients with asthma.
Topics: Acetates; Adult; Asthma; Basophils; Cyclopropanes; Cysteine; Female; Histamine; Humans; Immunologic Factors; Leukotriene Antagonists; Leukotrienes; Male; Quinolines; Sulfides | 2005 |
Response profiles to fluticasone and montelukast in mild-to-moderate persistent childhood asthma.
Topics: Acetates; Adolescent; Androstadienes; Asthma; Child; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Fluticasone; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Nitric Oxide; Quinolines; Sulfides | 2006 |
Randomized, double-blind, placebo-controlled study of montelukast for treating perennial allergic rhinitis.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Rhinitis, Allergic, Perennial; Sulfides; Treatment Outcome | 2005 |
Double-blind, randomised, controlled trial assessing controller medications in asthma.
Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Budesonide; Cyclopropanes; Delayed-Action Preparations; Double-Blind Method; Forced Expiratory Volume; Humans; Middle Aged; Patient Selection; Quinolines; Sulfides; Theophylline | 2006 |
Montelukast in asthma treatment in Croatia.
Topics: Acetates; Analysis of Variance; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Drug Therapy, Combination; Humans; Quinolines; Safety; Sulfides | 2005 |
Efficacy of montelukast in the treatment of nasal polyposis.
Topics: Acetates; Administration, Intranasal; Biopsy; Cyclopropanes; Eosinophilia; Humans; Leukotriene Antagonists; Nasal Polyps; Prospective Studies; Quinolines; Sulfides; Treatment Outcome | 2005 |
Randomized placebo-controlled trial comparing montelukast and cetirizine for treating perennial allergic rhinitis in children aged 2-6 yr.
Topics: Acetates; Anti-Allergic Agents; Cetirizine; Child; Child, Preschool; Cyclopropanes; Double-Blind Method; Female; Humans; Male; Quinolines; Rhinitis, Allergic, Perennial; Sulfides | 2006 |
Montelukast administered in the morning or evening to prevent exercise-induced bronchoconstriction in children.
Topics: Acetates; Adolescent; Analysis of Variance; Area Under Curve; Asthma, Exercise-Induced; Bronchial Hyperreactivity; Bronchoconstriction; Child; Cross-Over Studies; Cyclopropanes; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Probability; Prospective Studies; Quinolines; Risk Assessment; Severity of Illness Index; Sulfides; Treatment Outcome | 2006 |
Efficacy of montelukast during the allergy season in patients with chronic asthma and seasonal aeroallergen sensitivity.
Topics: Acetates; Administration, Oral; Adolescent; Adult; Aged; Anti-Asthmatic Agents; Asthma; Chronic Disease; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Logistic Models; Male; Middle Aged; Peak Expiratory Flow Rate; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides | 2006 |
Improvement of otitis media with effusion after treatment of asthma with leukotriene antagonists in children with co-existing disease.
Topics: Acetates; Administration, Inhalation; Adolescent; Asthma; Bronchodilator Agents; Budesonide; Child; Cyclopropanes; Drug Therapy, Combination; Humans; Leukotriene Antagonists; Otitis Media with Effusion; Quinolines; Sulfides; Terbutaline | 2005 |
Montelukast improves regional air-trapping due to small airways obstruction in asthma.
Topics: Acetates; Adolescent; Adult; Aged; Anti-Asthmatic Agents; Asthma; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Humans; Linear Models; Male; Methacholine Chloride; Middle Aged; Quinolines; Respiratory Function Tests; Statistics, Nonparametric; Sulfides; Tomography, X-Ray Computed; Treatment Outcome | 2006 |
Comparison of asthma treatment given in addition to inhaled corticosteroids on airway inflammation and responsiveness.
Topics: Acetates; Administration, Inhalation; Adult; Aged; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Budesonide; Cross-Over Studies; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Eosinophils; Ethanolamines; Formoterol Fumarate; Glucocorticoids; Humans; Leukocyte Count; Lung Volume Measurements; Male; Methacholine Chloride; Middle Aged; Quinolines; Sputum; Sulfides | 2006 |
Effectiveness of montelukast in the treatment of atopic dermatitis.
Topics: Acetates; Adolescent; Adult; Cyclopropanes; Dermatitis, Atopic; Female; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides; Treatment Outcome | 2006 |
Comparison of montelukast and pseudoephedrine in the treatment of allergic rhinitis.
Topics: Acetates; Administration, Oral; Adolescent; Adrenergic alpha-Agonists; Adult; Cyclopropanes; Double-Blind Method; Ephedrine; Female; Follow-Up Studies; Humans; Leukotriene Antagonists; Male; Middle Aged; Patient Satisfaction; Quality of Life; Quinolines; Retrospective Studies; Rhinitis, Allergic, Seasonal; Sulfides; Treatment Outcome | 2006 |
Influence of body mass index on the response to asthma controller agents.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Asthmatic Agents; Asthma; Beclomethasone; Body Mass Index; Cyclopropanes; Double-Blind Method; Female; Humans; Male; Middle Aged; Quinolines; Sulfides; Treatment Outcome | 2006 |
Telithromycin, but not montelukast, increases the plasma concentrations and effects of the cytochrome P450 3A4 and 2C8 substrate repaglinide.
Topics: Acetates; Adolescent; Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Biotransformation; Blood Glucose; Carbamates; Cross-Over Studies; Cyclopropanes; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Humans; Hypoglycemic Agents; Ketolides; Leukotriene Antagonists; Male; Piperidines; Quinolines; Sulfides | 2006 |
The effect of montelukast (10mg daily) and loratadine (10mg daily) on wheal, flare and itching reactions in skin prick tests.
Topics: Acetates; Allergens; Antipruritics; Capsules; Codeine; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Histamine; Humans; Leukotriene Antagonists; Loratadine; Male; Pollen; Pruritus; Quinolines; Skin; Skin Tests; Sulfides; Time Factors; Treatment Outcome; Urticaria | 2007 |
Efficacy and safety of montelukast in adults with asthma and allergic rhinitis.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Product Surveillance, Postmarketing; Quality of Life; Quinolines; Respiratory Hypersensitivity; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sulfides; Treatment Outcome | 2006 |
The effect of montelukast on nasal mucociliary clearance.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Mucociliary Clearance; Nasal Mucosa; Quinolines; Saccharin; Sulfides | 2006 |
Lack of tolerance to the protective effect of montelukast in exercise-induced bronchoconstriction in children.
Topics: Acetates; Anti-Asthmatic Agents; Asthma, Exercise-Induced; Bronchoconstriction; Case-Control Studies; Child; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Quinolines; Sulfides | 2006 |
Montelukast and zafirlukast do not affect the pharmacokinetics of the CYP2C8 substrate pioglitazone.
Topics: Acetates; Administration, Oral; Adult; Anti-Asthmatic Agents; Aryl Hydrocarbon Hydroxylases; Cyclopropanes; Cytochrome P-450 CYP2C8; Drug Administration Schedule; Drug Interactions; Female; Humans; Hypoglycemic Agents; Indoles; Male; Phenylcarbamates; Pioglitazone; Quinolines; Substrate Specificity; Sulfides; Sulfonamides; Thiazolidinediones; Tosyl Compounds | 2006 |
Effect of montelukast on peripheral airflow obstruction in children with asthma.
Topics: Acetates; Adolescent; Airway Obstruction; Airway Resistance; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Lung Volume Measurements; Male; Oscillometry; Plethysmography; Quinolines; Spirometry; Sulfides | 2006 |
Pharmacokinetics and safety of montelukast in children aged 3 to 6 months.
Topics: Acetates; Anti-Asthmatic Agents; Bronchiolitis; Cyclopropanes; Double-Blind Method; Female; Humans; Infant; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2006 |
Oral montelukast treatment of preschool-aged children with acute asthma.
Topics: Acetates; Acute Disease; Administration, Oral; Albuterol; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Child; Child, Preschool; Cyclopropanes; Drug Therapy, Combination; Female; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2006 |
Do the leukotriene receptor antagonists work in children with grass pollen-induced allergic rhinitis?
Topics: Acetates; Anti-Allergic Agents; Anti-Asthmatic Agents; Area Under Curve; Child; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Loratadine; Male; Poaceae; Quinolines; Respiratory Function Tests; Rhinitis, Allergic, Seasonal; Rhinomanometry; Sulfides; Time Factors; Treatment Outcome | 2006 |
Linear growth in prepubertal asthmatic children treated with montelukast, beclomethasone, or placebo: a 56-week randomized double-blind study.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Beclomethasone; Body Height; Child; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2006 |
Comparison of fluticasone propionate aqueous nasal spray and oral montelukast for the treatment of seasonal allergic rhinitis symptoms.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adult; Androstadienes; Anti-Allergic Agents; Anti-Asthmatic Agents; Cyclopropanes; Double-Blind Method; Female; Fluticasone; Humans; Leukotriene Antagonists; Male; Multicenter Studies as Topic; Nebulizers and Vaporizers; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides; Texas | 2006 |
Effects of a leukotriene receptor antagonist on exhaled leukotriene E4 and prostanoids in children with asthma.
Topics: Acetates; Allergens; Anti-Asthmatic Agents; Asthma; Biomarkers; Breath Tests; Child; Cross-Sectional Studies; Cyclopropanes; Dinoprost; Dinoprostone; Humans; Hypersensitivity; Leukotriene Antagonists; Leukotriene E4; Nitric Oxide; Quinolines; Skin Tests; Spirometry; Sulfides | 2006 |
Onset and duration of protection against exercise-induced bronchoconstriction by a single oral dose of montelukast.
Topics: Acetates; Administration, Oral; Adolescent; Adrenergic beta-Agonists; Adult; Area Under Curve; Asthma, Exercise-Induced; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Exercise Test; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Sulfides; Time Factors | 2006 |
Effect of obesity on clinical presentation and response to treatment in asthma.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Cyclopropanes; Cytokines; Disease Progression; Double-Blind Method; Female; Forced Expiratory Volume; Gastroesophageal Reflux; Humans; Male; Middle Aged; Obesity; Quinolines; Risk Factors; Sleep Wake Disorders; Sulfides; Theophylline; Treatment Outcome; Vital Capacity | 2006 |
Montelukast treatment attenuates the increase in myofibroblasts following low-dose allergen challenge.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Bronchial Provocation Tests; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fibroblasts; Forced Expiratory Volume; Humans; Male; Muscle, Smooth; Pneumonia; Quinolines; Respiratory System; Sulfides | 2006 |
Combination therapy with a long-acting beta-agonist and a leukotriene antagonist in moderate asthma.
Topics: Acetates; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Anti-Asthmatic Agents; Asthma; Combined Modality Therapy; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Placebos; Quinolines; Salmeterol Xinafoate; Sulfides; Treatment Outcome | 2007 |
Effect of multiple doses of montelukast on the pharmacokinetics of rosiglitazone, a CYP2C8 substrate, in humans.
Topics: Acetates; Adult; Cross-Over Studies; Cyclopropanes; Drug Interactions; Humans; Hypoglycemic Agents; Leukotriene Antagonists; Male; Quinolines; Rosiglitazone; Sulfides; Thiazolidinediones | 2007 |
Clinical trial of low-dose theophylline and montelukast in patients with poorly controlled asthma.
Topics: Acetates; Administration, Inhalation; Adult; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Forced Expiratory Flow Rates; Glucocorticoids; Humans; Leukotriene Antagonists; Lung; Male; Middle Aged; Quinolines; Severity of Illness Index; Sulfides; Theophylline; Treatment Outcome | 2007 |
Salmeterol response is not affected by beta2-adrenergic receptor genotype in subjects with persistent asthma.
Topics: Acetates; Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Drug Therapy, Combination; Female; Fluticasone; Genotype; Humans; Male; Middle Aged; Polymorphism, Genetic; Quinolines; Receptors, Adrenergic, beta-2; Respiratory Function Tests; Salmeterol Xinafoate; Sulfides | 2006 |
Efficacy and safety of montelukast as monotherapy in children with mild persistent asthma.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Female; Humans; Male; Quinolines; Sulfides; Treatment Outcome | 2006 |
Treatment with 400 microg of inhaled budesonide vs 200 microg of inhaled budesonide and oral montelukast in children with moderate persistent asthma: randomized controlled trial.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Anti-Asthmatic Agents; Asthma; Budesonide; Child; Cyclopropanes; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Male; Quinolines; Respiratory Function Tests; Sulfides | 2006 |
A randomized, double-blind trial of the effect of anti-asthma treatment on lung function in children with asthma.
Topics: Acetates; Adolescent; Airway Resistance; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Budesonide; Child; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Ethanolamines; Female; Forced Expiratory Volume; Formoterol Fumarate; Humans; Male; Maximal Midexpiratory Flow Rate; Plethysmography, Whole Body; Quinolines; Respiratory Function Tests; Sulfides | 2007 |
A randomized open-label comparative study of montelukast versus theophylline added to inhaled corticosteroid in asthmatic children.
Topics: Acetates; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Child; Cyclopropanes; Delayed-Action Preparations; Female; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides; Theophylline | 2006 |
Desloratadine in combination with montelukast suppresses the dermographometer challenge test papule, and is effective in the treatment of delayed pressure urticaria: a randomized, double-blind, placebo-controlled study.
Topics: Acetates; Administration, Oral; Adolescent; Adult; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Pressure; Quinolines; Skin Tests; Sulfides; Urticaria | 2006 |
Short-course montelukast for intermittent asthma in children: a randomized controlled trial.
Topics: Absenteeism; Acetates; Adolescent; Adrenergic beta-Agonists; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Drug Utilization; Emergency Service, Hospital; Female; Glucocorticoids; Hospitalization; Humans; Male; Office Visits; Physicians, Family; Prednisolone; Quinolines; Severity of Illness Index; Sulfides; Treatment Outcome | 2007 |
Long-term comparison of 3 controller regimens for mild-moderate persistent childhood asthma: the Pediatric Asthma Controller Trial.
Topics: Acetates; Adolescent; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Body Height; Child; Cyclopropanes; Drug Therapy, Combination; Female; Fluticasone; Forced Expiratory Volume; Humans; Male; Quinolines; Salmeterol Xinafoate; Sulfides | 2007 |
Combined mediator blockade or topical steroid for treating the unified allergic airway.
Topics: Acetates; Administration, Topical; Adolescent; Adult; Aged; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Beclomethasone; Cetirizine; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Administration Routes; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Quinolines; Rhinitis, Allergic, Perennial; Sulfides | 2007 |
Montelukast decreases plasma endothelin-1 and serum eosinophil cationic protein levels in paediatric atopic asthma.
Topics: Acetates; Administration, Intranasal; Adolescent; Albuterol; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Child; Cyclopropanes; Drug Administration Schedule; Endothelin-1; Eosinophil Cationic Protein; Female; Humans; Leukotriene Antagonists; Male; Quinolines; Severity of Illness Index; Sulfides; Time Factors | 2006 |
Montelukast with desloratadine or levocetirizine for the treatment of persistent allergic rhinitis.
Topics: Acetates; Adolescent; Adult; Aged; Anti-Asthmatic Agents; Cetirizine; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Eosinophil Cationic Protein; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Middle Aged; Nasal Lavage Fluid; Piperazines; Quinolines; Rhinitis, Allergic, Perennial; Rhinometry, Acoustic; Sulfides; Treatment Outcome | 2006 |
Effect of leukotriene modifier drugs on the safety of oral aspirin challenges.
Topics: Acetates; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Asthmatic Agents; Aspirin; Asthma; Cyclopropanes; Desensitization, Immunologic; Drug Hypersensitivity; Female; Forced Expiratory Volume; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Middle Aged; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome | 2006 |
Improvements in distal lung function correlate with asthma symptoms after treatment with oral montelukast.
Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Residual Volume; Respiratory Mechanics; Statistics as Topic; Sulfides; Vital Capacity | 2006 |
Effect of montelukast on symptoms and exhaled nitric oxide levels in 7- to 14-year-old children with seasonal allergic rhinitis.
Topics: Acetates; Adolescent; Child; Cyclopropanes; Double-Blind Method; Eosinophils; Female; Humans; Leukocyte Count; Leukotriene Antagonists; Male; Nitric Oxide; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides | 2006 |
Smoking affects response to inhaled corticosteroids or leukotriene receptor antagonists in asthma.
Topics: Acetates; Adult; Asthma; Beclomethasone; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Glucocorticoids; Humans; Leukotriene Antagonists; Male; Quality of Life; Quinolines; Respiratory Function Tests; Smoking; Sulfides; Treatment Outcome | 2007 |
The effect of montelukast on bronchial hyperreactivity in preschool children.
Topics: Acetates; Analysis of Variance; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Child, Preschool; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Quinolines; Spirometry; Sulfides; Treatment Outcome | 2007 |
Effect of azelastine, montelukast, and their combination on allergen-induced bronchoconstriction in asthma.
Topics: Acetates; Adult; Anti-Allergic Agents; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Phthalazines; Quinolines; Respiratory Function Tests; Sulfides | 2008 |
Regulation of stromal cell-derived factor-1 and exhaled nitric oxide in asthmatic children following montelukast and ketotifen treatment.
Topics: Acetates; Administration, Oral; Adolescent; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Budesonide; Calcium; Cell Line; Cell Movement; Chemokine CXCL12; Chemokines, CXC; Chemotaxis; Child; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Exhalation; Female; Flavonoids; Humans; Ketotifen; Male; Monocytes; Nitric Oxide; Peak Expiratory Flow Rate; Prospective Studies; Quinolines; Sulfides | 2007 |
[Polyposis nasi--improvement in quality of life by the influence of leukotrien receptor antagonists].
Topics: Acetates; Cyclopropanes; Data Interpretation, Statistical; Double-Blind Method; Eosinophil Cationic Protein; Female; Follow-Up Studies; Humans; Leukotriene Antagonists; Male; Middle Aged; Nasal Mucosa; Nasal Polyps; Placebos; Prospective Studies; Quality of Life; Quinolines; Sensitivity and Specificity; Sulfides; Surveys and Questionnaires; Time Factors; Treatment Outcome | 2007 |
Montelukast as add-on therapy to beta-agonists and late airway response.
Topics: Acetates; Administration, Oral; Adrenergic beta-Agonists; Adult; Anti-Asthmatic Agents; Asthma; Bronchi; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Placebos; Quinolines; Sulfides; Time Factors | 2007 |
Safety of leukotriene receptor antagonists in pregnancy.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Female; Fetus; Humans; Indoles; Infant, Newborn; Leukotriene Antagonists; Phenylcarbamates; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Quinolines; Safety; Sulfides; Sulfonamides; Teratogens; Tosyl Compounds | 2007 |
Adherence with montelukast or fluticasone in a long-term clinical trial: results from the mild asthma montelukast versus inhaled corticosteroid trial.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Androstadienes; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Female; Fluticasone; Humans; Male; Middle Aged; Patient Compliance; Quinolines; Sulfides | 2007 |
Montelukast in chronic graft-versus-host disease: a breath of fresh air?
Topics: Acetates; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Chronic Disease; Cyclopropanes; Graft vs Host Disease; Humans; Leukotriene Antagonists; Pilot Projects; Quinolines; Sulfides | 2007 |
Formoterol, montelukast, and budesonide in asthmatic children: effect on lung function and exhaled nitric oxide.
Topics: Acetates; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Breath Tests; Bronchodilator Agents; Budesonide; Child; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Ethanolamines; Female; Formoterol Fumarate; Humans; Male; Nitric Oxide; Quinolines; Sulfides | 2007 |
Roles of angiopoietin-1 and angiopoietin-2 on airway microvascular permeability in asthmatic patients.
Topics: Acetates; Adult; Androstadienes; Angiopoietin-1; Angiopoietin-2; Asthma; Biomarkers; Bronchi; Bronchodilator Agents; Capillary Permeability; Cyclopropanes; Female; Fluticasone; Follow-Up Studies; Humans; Immunoassay; Male; Microcirculation; Prognosis; Quinolines; Severity of Illness Index; Sputum; Sulfides; Vascular Endothelial Growth Factor A | 2007 |
Protection against exercise-induced bronchoconstriction two hours after a single oral dose of montelukast.
Topics: Acetates; Administration, Oral; Adolescent; Adult; Asthma, Exercise-Induced; Bronchoconstriction; Cross-Over Studies; Cyclopropanes; Exercise; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides; Time Factors | 2007 |
Pharmacogenetics of the 5-lipoxygenase biosynthetic pathway and variable clinical response to montelukast.
Topics: Acetates; Adolescent; Adult; Arachidonate 5-Lipoxygenase; Asthma; Cyclopropanes; Double-Blind Method; Female; Haplotypes; Humans; Male; Membrane Proteins; Middle Aged; Pharmacogenetics; Placebos; Quinolines; Receptors, Leukotriene; Signal Transduction; Sulfides | 2007 |
Effects of montelukast compared to double dose budesonide on airway inflammation and asthma control.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Aged; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Budesonide; Cyclopropanes; Double-Blind Method; Female; Humans; Male; Middle Aged; Quinolines; Sputum; Sulfides; Treatment Outcome | 2007 |
Randomized comparison of strategies for reducing treatment in mild persistent asthma.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Albuterol; Androstadienes; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Child; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluticasone; Forced Expiratory Volume; Humans; Kaplan-Meier Estimate; Male; Peak Expiratory Flow Rate; Quinolines; Salmeterol Xinafoate; Sulfides; Treatment Failure; Vital Capacity | 2007 |
Differential anti-inflammatory effects of large and small particle size inhaled corticosteroids in asthma.
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Beclomethasone; Chemistry, Pharmaceutical; Chlorofluorocarbons; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Eosinophils; Humans; Hydrocarbons, Fluorinated; Inflammation; Nitric Oxide; Particle Size; Quinolines; Sulfides | 2007 |
Montelukast decreased exhaled nitric oxide in children with perennial allergic rhinitis.
Topics: Acetates; Administration, Intranasal; Administration, Oral; Adolescent; Anti-Allergic Agents; Anti-Asthmatic Agents; Breath Tests; Budesonide; Child; Child, Preschool; Cromolyn Sodium; Cyclopropanes; Drug Therapy, Combination; Female; Follow-Up Studies; Glucocorticoids; Humans; Leukotriene Antagonists; Loratadine; Male; Nitric Oxide; Peak Expiratory Flow Rate; Quinolines; Rhinitis, Allergic, Perennial; Single-Blind Method; Sulfides; Treatment Outcome | 2007 |
Premedication with montelukast reduces local reactions of allergen immunotherapy.
Topics: Acetates; Adult; Aged; Allergens; Anaphylaxis; Animals; Cyclopropanes; Desensitization, Immunologic; Double-Blind Method; Drug Therapy, Combination; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Insect Bites and Stings; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Premedication; Quinolines; Sulfides; Wasp Venoms; Wasps | 2007 |
Single-dose montelukast or salmeterol as protection against exercise-induced bronchoconstriction.
Topics: Acetates; Adolescent; Adult; Albuterol; Anti-Asthmatic Agents; Bronchial Diseases; Bronchodilator Agents; Constriction, Pathologic; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Exercise; Female; Forced Expiratory Volume; Humans; Male; Quinolines; Salmeterol Xinafoate; Sulfides | 2007 |
Leukotriene receptor blockade does not prevent acute mountain sickness induced by normobaric hypoxia.
Topics: Acclimatization; Acetates; Administration, Oral; Adult; Altitude Sickness; Atmosphere Exposure Chambers; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Humans; Hypoxia; Leukotriene Antagonists; Leukotriene E4; Male; Premedication; Quinolines; Severity of Illness Index; Statistics, Nonparametric; Sulfides | 2007 |
Montelukast vs. inhaled low-dose budesonide as monotherapy in the treatment of mild persistent asthma: a randomized double blind controlled trial.
Topics: Acetates; Administration, Inhalation; Adolescent; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Budesonide; Child; Child, Preschool; Chronic Disease; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; India; Male; Quinolines; Sulfides | 2007 |
The effect of montelukast and low-dose theophylline on cardiovascular disease risk factors in asthmatics.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Cyclopropanes; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Interleukin-6; Lipids; Male; Middle Aged; Quinolines; Risk Factors; Sulfides; Theophylline | 2007 |
Placebo-controlled study of montelukast and budesonide on short-term growth in prepubertal asthmatic children.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Body Height; Budesonide; Child; Cyclopropanes; Double-Blind Method; Female; Humans; Leg; Male; Quinolines; Sulfides; Treatment Outcome | 2007 |
Attenuation of the September epidemic of asthma exacerbations in children: a randomized, controlled trial of montelukast added to usual therapy.
Topics: Acetates; Adolescent; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Age Factors; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Common Cold; Cyclopropanes; Disease Outbreaks; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Multivariate Analysis; Office Visits; Ontario; Quinolines; Schools; Seasons; Severity of Illness Index; Sex Factors; Sulfides; Surveys and Questionnaires | 2007 |
A double-blind, placebo-controlled trial of montelukast in adult atopic eczema.
Topics: Acetates; Adolescent; Adult; Cyclopropanes; Dermatitis, Atopic; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Placebos; Quinolines; Sulfides; Treatment Outcome | 2007 |
Salmeterol plus fluticasone propionate versus fluticasone propionate plus montelukast: a randomised controlled trial investigating the effects on airway inflammation in asthma.
Topics: Acetates; Adrenergic beta-Agonists; Adult; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Cyclopropanes; Cysteine; Double-Blind Method; Drug Combinations; Female; Fluticasone; Fluticasone-Salmeterol Drug Combination; Forced Expiratory Volume; Histamine; Humans; Interleukin-8; Leukotriene Antagonists; Leukotrienes; Lung; Male; Quinolines; Spirometry; Sputum; Sulfides; Time Factors; Treatment Outcome; United Kingdom | 2007 |
Prevalence of alpha-1 antitrypsin deficiency in poorly controlled asthma--results from the ALA-ACRC low-dose theophylline trial.
Topics: Acetates; Adolescent; Adult; Aged; alpha 1-Antitrypsin Deficiency; Asthma; Bronchodilator Agents; Cohort Studies; Cyclopropanes; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Phenotype; Prevalence; Quinolines; Statistics, Nonparametric; Sulfides; Theophylline; United States | 2007 |
Effect of different antiasthmatic treatments on exercise-induced bronchoconstriction in children with asthma.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Antigens, Dermatophagoides; Asthma; Bronchoconstriction; Bronchodilator Agents; Budesonide; Child; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Ethanolamines; Exercise; Female; Forced Expiratory Volume; Formoterol Fumarate; Glucocorticoids; Humans; Hypersensitivity; Male; Quinolines; Sulfides; Treatment Outcome | 2008 |
Comparative study of budesonide inhalation suspension and montelukast in young children with mild persistent asthma.
Topics: Acetates; Administration, Inhalation; Age Factors; Anti-Asthmatic Agents; Asthma; Budesonide; Child; Child, Preschool; Cyclopropanes; Female; Humans; Infant; Infant, Newborn; Male; Quinolines; Sulfides; Treatment Outcome | 2007 |
Effects of montelukast treatment and withdrawal on fractional exhaled nitric oxide and lung function in children with asthma.
Topics: Acetates; Administration, Oral; Analysis of Variance; Asthma; Child; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Nitric Oxide; Placebos; Quinolines; Skin Tests; Sulfides; Treatment Outcome; Vital Capacity | 2007 |
Effects of montelukast on subjective and objective outcome measures in preschool asthmatic children.
Topics: Acetates; Adenosine Monophosphate; Anti-Asthmatic Agents; Asthma; Child, Preschool; Cyclopropanes; Exhalation; Female; Forced Expiratory Volume; Humans; Infant; Leukotriene Antagonists; Male; Nitric Oxide; Prospective Studies; Quinolines; Respiratory Function Tests; Severity of Illness Index; Spirometry; Sulfides; Treatment Outcome; Vital Capacity | 2008 |
Pilot study of oral montelukast added to standard therapy for acute asthma exacerbations in children aged 6 to 14 years.
Topics: Acetates; Administration, Oral; Adolescent; Anti-Asthmatic Agents; Asthma; Child; Confidence Intervals; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Forced Expiratory Volume; Humans; Male; Pilot Projects; Probability; Prospective Studies; Quinolines; Recurrence; Reference Values; Risk Assessment; Severity of Illness Index; Statistics, Nonparametric; Sulfides; Treatment Outcome | 2008 |
Montelukast treatment in children with moderately severe atopic dermatitis.
Topics: Acetates; Administration, Oral; Adolescent; Blood Cell Count; Child; Child, Preschool; Cyclopropanes; Dermatitis, Atopic; Drug Administration Schedule; Eosinophils; Female; Histamine H1 Antagonists; Humans; Immunoglobulin E; Male; Quinolines; Sleep; Sulfides; Treatment Outcome | 2007 |
Pretreatment with albuterol versus montelukast for exercise-induced bronchospasm in children.
Topics: Acetates; Adolescent; Adrenergic beta-Agonists; Albuterol; Anti-Asthmatic Agents; Asthma, Exercise-Induced; Child; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Hospitals, University; Humans; Male; Prospective Studies; Quinolines; Spirometry; Sulfides | 2008 |
Pharmacokinetics and safety of montelukast oral granules in children 1 to 3 months of age with bronchiolitis.
Topics: Acetates; Anti-Asthmatic Agents; Area Under Curve; Asthma; Bronchiolitis; Child, Preschool; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Infant; Male; Nonlinear Dynamics; Powders; Quinolines; Sulfides | 2008 |
ALOX5 promoter genotype and response to montelukast in moderate persistent asthma.
Topics: Acetates; Adolescent; Adult; Age Distribution; Anti-Asthmatic Agents; Arachidonate 5-Lipoxygenase; Asthma; Cyclopropanes; Female; Forced Expiratory Volume; Genotype; Humans; Immunoglobulin E; Male; Middle Aged; Polymorphism, Genetic; Promoter Regions, Genetic; Quinolines; Sex Distribution; Sulfides; Tandem Repeat Sequences; Treatment Outcome | 2008 |
Leukotriene receptor antagonists: a good choice in the treatment of premenstrual asthma?
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Estrogens; Female; Follicle Stimulating Hormone; Humans; Leukotriene Antagonists; Luteinizing Hormone; Menstruation; Middle Aged; Premenstrual Syndrome; Progesterone; Quinolines; Respiratory Function Tests; Severity of Illness Index; Sulfides; Treatment Outcome | 2008 |
Effects of exercise training and montelukast in children with mild asthma.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Asthma, Exercise-Induced; Breath Tests; Bronchoconstriction; Bronchospirometry; Child; Cyclopropanes; Exercise Test; Exercise Therapy; Exhalation; Female; Humans; Italy; Male; Methacholine Chloride; Physical Fitness; Quinolines; Sulfides | 2008 |
Sleep quality in asthma: results of a large prospective clinical trial.
Topics: Acetates; Adult; Asthma; Bronchodilator Agents; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Quality of Life; Quinolines; Respiratory Function Tests; Sleep Wake Disorders; Sulfides; Surveys and Questionnaires; Theophylline | 2008 |
The efficacy of montelukast and airway mast cell profiles in patients with cough variant asthma.
Topics: Acetates; Adult; Aged; Anti-Asthmatic Agents; Asthma; Basophils; Cough; Cyclopropanes; Eosinophils; Female; Humans; Immunoglobulin E; Leukocyte Count; Leukotriene Antagonists; Male; Mast Cells; Middle Aged; Quinolines; Respiratory Mucosa; Sulfides; Treatment Outcome | 2008 |
Exposure to tobacco smoke increases leukotriene E4-related albuterol usage and response to montelukast.
Topics: Acetates; Adolescent; Albuterol; Anti-Asthmatic Agents; Asthma; Biomarkers; Breath Tests; Bronchodilator Agents; Child; Cotinine; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Leukotriene E4; Male; Nitric Oxide; Quinolines; Sex Factors; Sulfides; Tobacco Smoke Pollution | 2008 |
Urticaria unresponsive to antihistaminic treatment: an open study of therapeutic options based on histopathologic features.
Topics: Acetates; Adult; Anti-Infective Agents; Chronic Disease; Colchicine; Cyclopropanes; Dapsone; Drug Therapy, Combination; Female; Histamine H1 Antagonists; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Sulfides; Tubulin Modulators; Urticaria | 2008 |
Real-life effectiveness of Singulair (montelukast) in 506 children with mild to moderate asthma.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Patient Satisfaction; Quinolines; Severity of Illness Index; Sulfides; Treatment Outcome | 2008 |
Association of IL-13 polymorphisms with leukotriene receptor antagonist drug responsiveness in Korean children with exercise-induced bronchoconstriction.
Topics: Acetates; Anti-Asthmatic Agents; Asthma, Exercise-Induced; Bronchoconstriction; Child; Cyclopropanes; Drug Resistance; Exercise Test; Female; Forced Expiratory Volume; Gene Frequency; Genotype; Humans; Immunoglobulin E; Interleukin-13; Korea; Leukotriene Antagonists; Male; Polymorphism, Single Nucleotide; Quinolines; Sulfides | 2008 |
Therapeutic effect of montelukast, a cysteinyl leukotriene receptor 1 antagonist, on Japanese patients with seasonal allergic rhinitis.
Topics: Acetates; Adult; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Japan; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Rhinitis, Allergic, Seasonal; Severity of Illness Index; Sulfides | 2008 |
Study of montelukast for the treatment of respiratory symptoms of post-respiratory syncytial virus bronchiolitis in children.
Topics: Acetates; Bronchiolitis; Child, Preschool; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Infant; Leukotriene Antagonists; Male; Pilot Projects; Quinolines; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Retrospective Studies; Severity of Illness Index; Sulfides; Treatment Outcome | 2008 |
Fluticasone or montelukast for preschool children with asthma-like symptoms: Randomized controlled trial.
Topics: Acetates; Administration, Oral; Androstadienes; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Child, Preschool; Cyclopropanes; Double-Blind Method; Female; Fluticasone; Humans; Male; Metered Dose Inhalers; Netherlands; Outpatient Clinics, Hospital; Quinolines; Respiratory Function Tests; Sulfides; Tablets; Time Factors; Treatment Outcome | 2008 |
Prevention of exercise-induced asthma by a fixed combination of disodium cromoglycate plus reproterol compared with montelukast in young patients.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma, Exercise-Induced; Bronchodilator Agents; Child, Preschool; Cromolyn Sodium; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Combinations; Exercise Test; Female; Forced Expiratory Flow Rates; Humans; Male; Metaproterenol; Quinolines; Sulfides; Theophylline | 2008 |
Efficacy and tolerability of salmeterol/fluticasone propionate versus montelukast in childhood asthma: A prospective, randomized, double-blind, double-dummy, parallel-group study.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adolescent; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Child; Cyclopropanes; Double-Blind Method; Drug Combinations; Female; Fluticasone; Humans; Male; Peak Expiratory Flow Rate; Prospective Studies; Quality of Life; Quinolines; Sulfides | 2008 |
The effect of montelukast on exhaled nitric oxide of alveolar and bronchial origin in inhaled corticosteroid-treated asthma.
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Adult; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchi; Cyclopropanes; Female; Fluticasone; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Nitric Oxide; Prospective Studies; Quinolines; Sulfides | 2009 |
Efficacy comparison of levocetirizine vs montelukast in ragweed sensitized patients.
Topics: Abdominal Pain; Acetates; Adolescent; Adult; Aged; Ambrosia; Cetirizine; Cyclopropanes; Double-Blind Method; Exanthema; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Male; Middle Aged; Patient Satisfaction; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides; Time Factors; Treatment Outcome | 2008 |
A double-blind non-inferiority clinical study of montelukast, a cysteinyl leukotriene receptor 1 antagonist, compared with pranlukast in patients with seasonal allergic rhinitis.
Topics: Acetates; Adult; Chromones; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Nasal Obstruction; Quinolines; Rhinitis, Allergic, Seasonal; Severity of Illness Index; Sleep Initiation and Maintenance Disorders; Sneezing; Sulfides; Treatment Outcome | 2008 |
Deterioration in asthma control when subjects receiving fluticasone propionate/salmeterol 100/50 mcg Diskus are "stepped-down".
Topics: Acetates; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Fluticasone; Fluticasone-Salmeterol Drug Combination; Forced Expiratory Flow Rates; Humans; Kaplan-Meier Estimate; Male; Patient Satisfaction; Peak Expiratory Flow Rate; Quinolines; Salmeterol Xinafoate; Sulfides; Surveys and Questionnaires | 2008 |
Azithromycin or montelukast as inhaled corticosteroid-sparing agents in moderate-to-severe childhood asthma study.
Topics: Acetates; Adolescent; Albuterol; Anti-Bacterial Agents; Asthma; Azithromycin; Bronchodilator Agents; Budesonide; Child; Cyclopropanes; Double-Blind Method; Female; Glucocorticoids; Humans; Male; Medication Adherence; Quinolines; Salmeterol Xinafoate; Severity of Illness Index; Sulfides; Time Factors | 2008 |
Quality of life in patients with persistent allergic rhinitis treated with montelukast alone or in combination with levocetirizine or desloratadine.
Topics: Acetates; Adolescent; Adult; Aged; Cetirizine; Chronic Disease; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Interactions; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Quality of Life; Quinolines; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sulfides; Treatment Outcome | 2008 |
Episodic use of an inhaled corticosteroid or leukotriene receptor antagonist in preschool children with moderate-to-severe intermittent wheezing.
Topics: Acetates; Administration, Inhalation; Albuterol; Bronchodilator Agents; Budesonide; Child, Preschool; Cyclopropanes; Double-Blind Method; Female; Glucocorticoids; Humans; Infant; Leukotriene Antagonists; Male; Quinolines; Respiratory Sounds; Respiratory Tract Diseases; Sulfides | 2008 |
Montelukast as an adjunct to oral and inhaled steroid therapy in chronic nasal polyposis.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adult; Aged; Aged, 80 and over; Budesonide; Cohort Studies; Cyclopropanes; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Leukotriene Antagonists; Male; Middle Aged; Nasal Polyps; Prednisolone; Quinolines; Sulfides; Treatment Outcome | 2008 |
A double-blind, placebo-controlled, randomized trial of montelukast for acute bronchiolitis.
Topics: Acetates; Acute Disease; Bronchiolitis; Cross-Over Studies; Cyclopropanes; Cytokines; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Delivery Systems; Female; Follow-Up Studies; Hospitalization; Humans; Infant; Infant, Newborn; Inflammation Mediators; Leukotriene Antagonists; Male; Probability; Prospective Studies; Quinolines; Severity of Illness Index; Statistics, Nonparametric; Sulfides; Treatment Outcome | 2008 |
Impulse oscillometry versus spirometry in a long-term study of controller therapy for pediatric asthma.
Topics: Acetates; Adolescent; Albuterol; Androstadienes; Asthma; Biomarkers; Child; Cyclopropanes; Double-Blind Method; Female; Fluticasone; Forced Expiratory Volume; Humans; Male; Oscillometry; Quinolines; Salmeterol Xinafoate; Spirometry; Sulfides; Vital Capacity | 2009 |
Efficacy of leukotriene receptor antagonist with an anti-H1 receptor antagonist for treatment of chronic idiopathic urticaria.
Topics: Acetates; Adolescent; Adult; Cetirizine; Chronic Disease; Cyclopropanes; Drug Therapy, Combination; Famotidine; Female; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Hydroxyzine; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Single-Blind Method; Sulfides; Urticaria; Young Adult | 2009 |
Effects of loratadine/montelukast on vigilance and alertness task performance in a simulated cabin environment.
Topics: Acetates; Adult; Altitude; Anti-Allergic Agents; Atmospheric Pressure; Cross-Over Studies; Cyclopropanes; Diphenhydramine; Double-Blind Method; Drug Combinations; Humans; Loratadine; Male; Psychomotor Performance; Quinolines; Sulfides; Young Adult | 2009 |
[Therapeutic efficacy and follow-up study of inhaled corticosteroids vs. oral montelukast in treatment of cough variant asthma].
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Beclomethasone; Child; Child, Preschool; Cough; Cyclopropanes; Female; Follow-Up Studies; Humans; Male; Quinolines; Risk Factors; Sulfides; Treatment Outcome | 2008 |
Montelukast is not effective in controlling allergic symptoms outside the airways: a randomised double-blind placebo-controlled crossover study.
Topics: Acetates; Adolescent; Adult; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Humans; Hypersensitivity; Leukotriene Antagonists; Male; Pollen; Quinolines; Sulfides; Treatment Failure; Young Adult | 2009 |
Molecular mechanism of the additive effects of leukotriene modifier in asthmatic patients receiving steroid therapy.
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Adult; Asthma; Chemokine CCL5; Chromones; Cyclopropanes; Cysteine; Cytokines; Drug Synergism; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Leukotrienes; Male; Middle Aged; Quinolines; Sulfides | 2009 |
Single-dose desloratadine and montelukast and allergen-induced late airway responses.
Topics: Acetates; Adult; Allergens; Analysis of Variance; Anti-Asthmatic Agents; Asthma; Bronchial Provocation Tests; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Eosinophils; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Loratadine; Male; Methacholine Chloride; Middle Aged; Nitric Oxide; Placebos; Quinolines; Respiratory Function Tests; Sputum; Sulfides; Treatment Outcome | 2009 |
Efficacy of add-on montelukast in patients with non-controlled asthma: a Belgian open-label study.
Topics: Acetates; Adult; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Belgium; Budesonide; Cyclopropanes; Drug Therapy, Combination; Ethanolamines; Female; Fluticasone; Formoterol Fumarate; Humans; Male; Middle Aged; Quinolines; Salmeterol Xinafoate; Sulfides; Surveys and Questionnaires | 2009 |
5-lipoxygenase pharmacogenetics in asthma: overlap with Cys-leukotriene receptor antagonist loci.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Cysteine; Female; Forced Expiratory Volume; Genotype; Humans; Hydroxyurea; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Middle Aged; Polymorphism, Single Nucleotide; Quinolines; Receptors, Leukotriene; Sulfides | 2009 |
Acetylsalicylic acid and montelukast block mast cell mediator-related symptoms during rapid desensitization.
Topics: Acetates; Aged; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Colonic Neoplasms; Cyclopropanes; Desensitization, Immunologic; Drug Hypersensitivity; Drug Therapy, Combination; Female; Humans; Inflammation Mediators; Mast Cells; Middle Aged; Organoplatinum Compounds; Ovarian Neoplasms; Quinolines; Reference Standards; Sulfides | 2009 |
Montelukast and bronchial inflammation in asthma: a randomised, double-blind placebo-controlled trial.
Topics: Acetates; Adolescent; Adult; Analysis of Variance; Anti-Asthmatic Agents; Asthma; Cell Count; Cyclopropanes; Double-Blind Method; Eosinophils; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Mast Cells; Middle Aged; Quinolines; Respiratory Mucosa; Sulfides; Treatment Outcome; Young Adult | 2009 |
The effect of an inhaled corticosteroid on glucose control in type 2 diabetes.
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Aged; Androstadienes; Anti-Asthmatic Agents; Bronchodilator Agents; Cross-Over Studies; Cyclopropanes; Diabetes Complications; Diabetes Mellitus, Type 2; Double-Blind Method; Fluticasone; Glucose; Glycated Hemoglobin; Humans; Male; Middle Aged; Placebos; Pulmonary Disease, Chronic Obstructive; Quinolines; Sulfides; Treatment Outcome | 2009 |
The targeted oral, once-daily phosphodiesterase 4 inhibitor roflumilast and the leukotriene receptor antagonist montelukast do not exhibit significant pharmacokinetic interactions.
Topics: Acetates; Administration, Oral; Adolescent; Adult; Aminopyridines; Anti-Asthmatic Agents; Benzamides; Cyclopropanes; Drug Interactions; Drug Therapy, Combination; Humans; Leukotriene Antagonists; Male; Middle Aged; Phosphodiesterase Inhibitors; Quinolines; Sulfides | 2009 |
Signs and symptoms that precede wheezing in children with a pattern of moderate-to-severe intermittent wheezing.
Topics: Acetates; Adult; Albuterol; Anti-Asthmatic Agents; Asthenia; Bronchodilator Agents; Budesonide; Causality; Child, Preschool; Cough; Cyclopropanes; Double-Blind Method; Female; Glucocorticoids; Humans; Infant; Male; Quinolines; Respiratory Sounds; Respiratory Tract Infections; Sensitivity and Specificity; Socioeconomic Factors; Sulfides; Surveys and Questionnaires | 2009 |
Montelukast for treatment of refractory pruritus in patients on hemodialysis.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Cross-Over Studies; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Pruritus; Quinolines; Renal Dialysis; Sulfides; Young Adult | 2007 |
Montelukast in the treatment of duodenal eosinophilia in children with dyspepsia: effect on eosinophil density and activation in relation to pharmacokinetics.
Topics: Acetates; Adolescent; Biopsy; Cell Count; Child; Cyclopropanes; Cytokines; Dose-Response Relationship, Drug; Duodenum; Dyspepsia; Eosinophilia; Eosinophils; Female; Humans; Intestinal Mucosa; Leukotriene Antagonists; Male; Quinolines; Sulfides; Treatment Outcome | 2009 |
Efficacy of loratadine-montelukast on nasal congestion in patients with seasonal allergic rhinitis in an environmental exposure unit.
Topics: Acetates; Administration, Intranasal; Adult; Ambrosia; Anti-Allergic Agents; Anti-Asthmatic Agents; Cyclopropanes; Double-Blind Method; Female; Humans; Loratadine; Male; Pollen; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides; Tablets; Treatment Outcome | 2009 |
The efficacy of montelukast during the allergy season in pediatric patients with persistent asthma and seasonal aeroallergen sensitivity.
Topics: Acetates; Administration, Oral; Adolescent; Asthma; Child; Cross-Over Studies; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Forced Expiratory Volume; Humans; Hypersensitivity; Male; Multivariate Analysis; Probability; Prognosis; Quinolines; Reference Values; Respiratory Function Tests; Rhinitis, Allergic, Seasonal; Risk Assessment; Severity of Illness Index; Sulfides; Treatment Outcome | 2009 |
A randomized study comparing the effect of loratadine added to montelukast with montelukast, loratadine, and beclomethasone monotherapies in patients with chronic asthma.
Topics: Acetates; Adolescent; Adult; Aged; Anti-Allergic Agents; Asthma; Beclomethasone; Chronic Disease; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Loratadine; Male; Middle Aged; Quality of Life; Quinolines; Sulfides; Young Adult | 2009 |
Asthma morbidity among inner-city adolescents receiving guidelines-based therapy: role of predictors in the setting of high adherence.
Topics: Acetates; Adolescent; Adrenergic beta-Agonists; Albuterol; Allergens; Androstadienes; Anti-Asthmatic Agents; Asthma; Biomarkers; Child; Cyclopropanes; Double-Blind Method; Exhalation; Female; Fluticasone; Follow-Up Studies; Humans; Immunoglobulin E; Male; Nitric Oxide; Patient Compliance; Practice Guidelines as Topic; Quinolines; Salmeterol Xinafoate; Skin Tests; Sulfides; Urban Population; Young Adult | 2009 |
Randomized trial of the effect of drug presentation on asthma outcomes: the American Lung Association Asthma Clinical Research Centers.
Topics: Acetates; Administration, Oral; Adult; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Double-Blind Method; Female; Follow-Up Studies; Humans; Leukotriene Antagonists; Lung; Male; Middle Aged; Quinolines; Sulfides; Surveys and Questionnaires; Treatment Outcome | 2009 |
Can montelukast shorten prednisolone therapy in children with mild to moderate acute asthma? A randomized controlled trial.
Topics: Acetates; Adolescent; Anti-Inflammatory Agents; Asthma; Bronchodilator Agents; Child; Child, Preschool; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Emergency Service, Hospital; Female; Hospitalization; Humans; Leukotriene Antagonists; Male; Prednisolone; Quinolines; Sulfides; Treatment Outcome | 2009 |
Montelukast does not prevent reactive airway disease in young children hospitalized for RSV bronchiolitis.
Topics: Acetates; Bronchiolitis, Viral; Bronchodilator Agents; Chi-Square Distribution; Cough; Cyclopropanes; Double-Blind Method; Follow-Up Studies; Hospitalization; Humans; Infant; Prospective Studies; Quinolines; Respiratory Hypersensitivity; Respiratory Sounds; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Statistics, Nonparametric; Sulfides; Treatment Outcome | 2009 |
[Efficacy of montelukas in the prevention of acute asthma episode in children].
Topics: Acetates; Acute Disease; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2009 |
Leukotriene receptor antagonist in the treatment of childhood allergic rhinitis--a randomized placebo-controlled study.
Topics: Acetates; Adolescent; Asthma; Child; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Male; Quinolines; Rhinitis, Allergic, Perennial; Rhinometry, Acoustic; Sulfides; Terfenadine | 2009 |
Clinical studies of the DP1 antagonist laropiprant in asthma and allergic rhinitis.
Topics: Acetates; Adolescent; Adult; Aged; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Cetirizine; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Genetic Predisposition to Disease; Haplotypes; Humans; Indoles; Male; Middle Aged; Promoter Regions, Genetic; Quinolines; Receptors, Prostaglandin; Rhinitis, Allergic, Seasonal; Sulfides; Young Adult | 2009 |
Clinical studies of combination montelukast and loratadine in patients with seasonal allergic rhinitis.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Beclomethasone; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides; Treatment Outcome; Young Adult | 2009 |
Pilot study on recurrent aphthous stomatitis (RAS): a randomized placebo-controlled trial for the comparative therapeutic effects of systemic prednisone and systemic montelukast in subjects unresponsive to topical therapy.
Topics: Acetates; Adolescent; Adult; Cyclopropanes; Double-Blind Method; Female; Glucocorticoids; Humans; Leukotriene Antagonists; Male; Middle Aged; Pain; Pilot Projects; Prednisolone; Quinolines; Stomatitis, Aphthous; Sulfides; Treatment Outcome | 2010 |
Efficacy of montelukast, a leukotriene receptor antagonist, for the treatment of dysmenorrhea: a prospective, double-blind, randomized, placebo-controlled study.
Topics: Acetates; Adult; Cyclopropanes; Double-Blind Method; Dysmenorrhea; Female; Humans; Leukotriene Antagonists; Prospective Studies; Quinolines; Sulfides | 2010 |
Predicting short term response to anti-inflammatory therapy in young children with asthma.
Topics: Acetates; Algorithms; Androstadienes; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Biomarkers, Pharmacological; Breath Tests; Child; Child, Preschool; Cyclopropanes; Female; Fluticasone; Humans; Male; Prognosis; Quinolines; Sulfides; Time Factors; Treatment Outcome | 2010 |
Evaluation of 3-5 months' add-on therapy with montelukast in patients with non-controlled asthma in Austria: the STAR open-label, real-world, observational study.
Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Austria; Child; Cohort Studies; Cyclopropanes; Female; Humans; Male; Middle Aged; Practice Guidelines as Topic; Quality of Life; Quinolines; Sulfides; Surveys and Questionnaires; Time Factors | 2010 |
Add-on montelukast to inhaled corticosteroids protects against excessive airway narrowing.
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Adult; Asthma; Bronchial Hyperreactivity; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Methacholine Chloride; Middle Aged; Quinolines; Sulfides; Treatment Outcome; Young Adult | 2010 |
One-year evaluation of combined treatment with an intranasal corticosteroid and montelukast for chronic rhinosinusitis associated with asthma.
Topics: Acetates; Administration, Intranasal; Adrenal Cortex Hormones; Adult; Aged; Androstadienes; Anti-Allergic Agents; Asthma; Chronic Disease; Cyclopropanes; Drug Therapy, Combination; Eosinophils; Female; Fluticasone; Humans; Leukotriene Antagonists; Male; Middle Aged; Nasal Polyps; Quinolines; Rhinitis, Allergic, Perennial; Sinusitis; Sulfides; Tomography, X-Ray Computed; Treatment Outcome | 2010 |
A randomized placebo-controlled study of intravenous montelukast for the treatment of acute asthma.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Infusions, Intravenous; Male; Middle Aged; Quinolines; Respiratory Function Tests; Sulfides; Young Adult | 2010 |
A randomized intervention of montelukast for post-bronchiolitis: effect on eosinophil degranulation.
Topics: Acetates; Acute Disease; Bronchiolitis, Viral; Cell Degranulation; Cyclopropanes; Double-Blind Method; Eosinophil-Derived Neurotoxin; Eosinophils; Humans; Infant; Quinolines; Recurrence; Respiratory Sounds; Respiratory Syncytial Virus Infections; Sulfides | 2010 |
Step-up therapy for children with uncontrolled asthma receiving inhaled corticosteroids.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adolescent; Adrenergic beta-Agonists; Albuterol; Androstadienes; Asthma; Bronchodilator Agents; Child; Cross-Over Studies; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Eczema; Female; Fluticasone; Forced Expiratory Volume; Glucocorticoids; Humans; Leukotriene Antagonists; Logistic Models; Male; Prednisone; Quinolines; Salmeterol Xinafoate; Sulfides; Treatment Outcome | 2010 |
Effect of inhaled steroid and montelukast on clinical symptoms in children with newly diagnosed asthma: a pilot study.
Topics: Acetates; Administration, Inhalation; Adolescent; Animals; Antigens, Dermatophagoides; Asthma; Budesonide; Child; Child, Preschool; Cyclopropanes; Evidence-Based Medicine; Female; Humans; Male; Pilot Projects; Pyroglyphidae; Quinolines; Respiratory Function Tests; Sulfides | 2010 |
Montelukast as monotherapy in children with mild persistent asthma.
Topics: Acetates; Adolescent; Asthma; Child; Child, Preschool; Cyclopropanes; Disease Progression; Female; Humans; Leukotriene Antagonists; Male; Peak Expiratory Flow Rate; Prospective Studies; Quinolines; Severity of Illness Index; Sulfides; Treatment Outcome | 2009 |
A randomized, placebo-controlled study of intravenous montelukast in children with acute asthma.
Topics: Acetates; Acute Disease; Adolescent; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Hospitalization; Humans; Injections, Intravenous; Leukotriene Antagonists; Male; Quinolines; Sulfides; Treatment Failure | 2010 |
Exercise-induced wheeze: Fraction of exhaled nitric oxide-directed management.
Topics: Acetates; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Androstadienes; Anti-Asthmatic Agents; Asthma, Exercise-Induced; Bronchoconstriction; Bronchodilator Agents; Child; Cromolyn Sodium; Cyclopropanes; Ethanolamines; Exercise; Female; Fluticasone; Forced Expiratory Volume; Formoterol Fumarate; Humans; Male; Mannitol; Middle Aged; Nitric Oxide; Quinolines; Respiratory Sounds; Sulfides; Young Adult | 2010 |
Effects of montelukast on quality of life in patients with persistent allergic rhinitis.
Topics: Acetates; Administration, Oral; Adult; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Quality of Life; Quinolines; Rhinitis, Allergic, Perennial; Sulfides; Tablets; Treatment Outcome | 2010 |
Montelukast treatment may alter the early efficacy of immunotherapy in children with asthma.
Topics: Acetates; Administration, Inhalation; Animals; Anti-Asthmatic Agents; Antigens, Dermatophagoides; Asthma; Budesonide; Chemotherapy, Adjuvant; Child; Cyclopropanes; Desensitization, Immunologic; Double-Blind Method; Follow-Up Studies; Humans; Lymphocyte Activation; Pyroglyphidae; Quinolines; Sulfides; T-Lymphocytes, Regulatory; Time Factors | 2010 |
Randomized open comparison of montelukast and sublingual immunotherapy as add-on treatment in moderate persistent asthma due to birch pollen.
Topics: Acetates; Administration, Sublingual; Adolescent; Adult; Aged; Antigens, Plant; Asthma; Betula; Cell Count; Cyclopropanes; Desensitization, Immunologic; Disease Progression; Eosinophilia; Female; Follow-Up Studies; Humans; Leukotriene Antagonists; Male; Middle Aged; Nasal Obstruction; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides | 2010 |
Acute additive effect of montelukast and beclomethasone on AMP induced bronchoconstriction.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Anti-Inflammatory Agents; Asthma; Beclomethasone; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Male; Quinolines; Sulfides; Treatment Outcome; Young Adult | 2010 |
Effect of addition of single dose of oral montelukast to standard treatment in acute moderate to severe asthma in children between 5 and 15 years of age: a randomised, double-blind, placebo controlled trial.
Topics: Acetates; Administration, Oral; Adolescent; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Male; Quinolines; Severity of Illness Index; Sulfides | 2010 |
Sodium cromoglycate alone and in combination with montelukast on the airway response to mannitol in asthmatic subjects.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Cromolyn Sodium; Cyclopropanes; Dose-Response Relationship, Drug; Drug Combinations; Female; Forced Expiratory Volume; Humans; Male; Mannitol; Quinolines; Sulfides | 2010 |
Onset of action of loratadine/montelukast in seasonal allergic rhinitis patients exposed to grass pollen.
Topics: Acetates; Adult; Anti-Allergic Agents; Anti-Asthmatic Agents; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Combinations; Endpoint Determination; Female; Humans; Loratadine; Male; Poaceae; Pollen; Prospective Studies; Quinolines; Rhinitis, Allergic, Seasonal; Rhinomanometry; Sulfides; Young Adult | 2010 |
Effect of montelukast or salmeterol added to inhaled fluticasone on exercise-induced bronchoconstriction in children.
Topics: Acetates; Adolescent; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchoconstriction; Child; Cross-Sectional Studies; Cyclopropanes; Double-Blind Method; Exercise; Female; Fluticasone; Forced Expiratory Volume; Humans; Male; Quinolines; Salmeterol Xinafoate; Sulfides | 2010 |
Gemfibrozil markedly increases the plasma concentrations of montelukast: a previously unrecognized role for CYP2C8 in the metabolism of montelukast.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cross-Over Studies; Cyclopropanes; Cytochrome P-450 CYP2C8; DNA; Drug Interactions; Female; Gemfibrozil; Genotype; Glucuronides; Half-Life; Humans; Hypolipidemic Agents; Leukotriene Antagonists; Male; Mass Spectrometry; Microsomes, Liver; Quinolines; Sulfides; Young Adult | 2010 |
Effect of the addition of montelukast to fluticasone propionate for the treatment of perennial allergic rhinitis.
Topics: Acetates; Adolescent; Adult; Androstadienes; Anti-Inflammatory Agents; Chemotherapy, Adjuvant; Cyclopropanes; Feasibility Studies; Female; Fluticasone; Humans; Leukotriene Antagonists; Male; Middle Aged; Quality of Life; Quinolines; Rhinitis, Allergic, Perennial; Skin Tests; Sulfides; Surveys and Questionnaires; Treatment Outcome | 2010 |
The Back to School asthma study: the effect of montelukast on asthma burden when initiated prophylactically at the start of the school year.
Topics: Acetates; Adolescent; Anti-Allergic Agents; Asthma; Child; Clinical Protocols; Cyclopropanes; Disease Progression; Female; Humans; Male; Periodicity; Quinolines; Schools; Seasons; Sulfides; Treatment Outcome | 2010 |
Montelukast added to fluticasone propionate does not alter inflammation or outcomes.
Topics: Acetates; Administration, Inhalation; Adult; Androstadienes; Asthma; Bronchi; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Eosinophilia; Female; Fluticasone; Forced Expiratory Volume; Humans; Male; Quinolines; Sulfides; Treatment Outcome | 2010 |
Efficacy of leukotriene antagonists as concomitant therapy in allergic rhinitis.
Topics: Acetates; Adult; Airway Resistance; Anti-Allergic Agents; Case-Control Studies; Cyclopropanes; Drug Therapy, Combination; Female; Humans; Leukotriene Antagonists; Male; Pain Measurement; Patient Satisfaction; Quinolines; Rhinitis, Allergic, Perennial; Rhinomanometry; Sulfides; Terfenadine; Treatment Outcome | 2010 |
Urinary leukotriene E4/exhaled nitric oxide ratio and montelukast response in childhood asthma.
Topics: Acetates; Adolescent; Age of Onset; Asthma; Biomarkers; Child; Cyclopropanes; Female; Humans; Immunoglobulin E; Leukotriene Antagonists; Leukotriene E4; Male; Nitric Oxide; Predictive Value of Tests; Quinolines; Sulfides; Treatment Outcome | 2010 |
Baseline predictors of placebo response in exercise-induced bronchoconstriction (EIB): pooled regression analysis >from three studies of montelukast in EIB.
Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Asthma, Exercise-Induced; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Placebo Effect; Quinolines; Sulfides; Young Adult | 2010 |
A subgroup analysis of the MONICA study: a 12-month, open-label study of add-on montelukast treatment in asthma patients.
Topics: Acetates; Adrenergic beta-2 Receptor Agonists; Age Factors; Anti-Asthmatic Agents; Asthma; Clinical Trials as Topic; Cyclopropanes; Drug Therapy, Combination; Glucocorticoids; Humans; Leukotriene Antagonists; Quality of Life; Quinolines; Severity of Illness Index; Sex Factors; Sulfides; Time Factors | 2010 |
A prospective, randomized, placebo-controlled, double-blind study of montelukast's effect on persistent middle ear effusion.
Topics: Acetates; Child; Child, Preschool; Chronic Disease; Cyclopropanes; Double-Blind Method; Humans; Leukotriene Antagonists; Otitis Media with Effusion; Quinolines; Sulfides; Treatment Failure | 2010 |
Bioequivalence study of two generic formulations of 10 mg montelukast tablets in healthy Thai male volunteers.
Topics: Acetates; Adolescent; Adult; Area Under Curve; Cross-Over Studies; Cyclopropanes; Drugs, Generic; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides; Tablets; Thailand; Therapeutic Equivalency; Young Adult | 2010 |
A phase I randomized, placebo-controlled, dose-exploration study of single-dose inhaled montelukast in patients with chronic asthma.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Chronic Disease; Cross-Over Studies; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Forced Expiratory Volume; Humans; Least-Squares Analysis; Leukotriene Antagonists; Middle Aged; Quinolines; Sulfides; Young Adult | 2010 |
Oral montelukast in acute asthma exacerbations: a randomised, double-blind, placebo-controlled trial.
Topics: Acetates; Acute Disease; Administration, Oral; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glucocorticoids; Hospitalization; Humans; Leukotriene Antagonists; Male; Middle Aged; Peak Expiratory Flow Rate; Quinolines; Sulfides; Treatment Outcome; Young Adult | 2011 |
Effect of citrus juice and SLCO2B1 genotype on the pharmacokinetics of montelukast.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Area Under Curve; Asthma; Beverages; Citrus paradisi; Citrus sinensis; Cross-Over Studies; Cyclopropanes; Female; Florida; Food-Drug Interactions; Fruit; Heterozygote; Homozygote; Humans; Isotonic Solutions; Leukotriene Antagonists; Male; Models, Biological; Organic Anion Transporters; Phenotype; Polymorphism, Genetic; Quinolines; Sulfides | 2011 |
Randomized controlled trial of fish oil and montelukast and their combination on airway inflammation and hyperpnea-induced bronchoconstriction.
Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Breath Tests; Bronchitis; Bronchoconstriction; Cyclopropanes; Double-Blind Method; Exhalation; Female; Fish Oils; Humans; Male; Quinolines; Respiratory Function Tests; Sulfides | 2010 |
Cysteinyl leukotriene antagonism inhibits bronchoconstriction in response to hypertonic saline inhalation in asthma.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Bronchoconstriction; Cyclopropanes; Cysteine; Epidemiologic Methods; Female; Humans; Leukotriene Antagonists; Leukotrienes; Male; Middle Aged; Polymorphism, Genetic; Quinolines; Receptors, Leukotriene; Saline Solution, Hypertonic; Sulfides; Young Adult | 2011 |
Cost-effectiveness analysis of fluticasone versus montelukast in children with mild-to-moderate persistent asthma in the Pediatric Asthma Controller Trial.
Topics: Acetates; Androstadienes; Anti-Asthmatic Agents; Asthma; Child; Cost-Benefit Analysis; Cyclopropanes; Female; Fluticasone; Humans; Male; Quinolines; Respiratory Function Tests; Sulfides | 2011 |
Efficacy and safety of montelukast add-on therapy in allergic rhinitis.
Topics: Acetates; Administration, Intranasal; Administration, Oral; Adult; Androstadienes; Anti-Allergic Agents; Cetirizine; Cyclopropanes; Drug Therapy, Combination; Female; Fluticasone; Follow-Up Studies; Humans; Leukotriene Antagonists; Male; Nasal Sprays; Prospective Studies; Quinolines; Rhinitis; Sulfides | 2010 |
Inhaled corticosteroids may have a beneficial effect on bone metabolism in newly diagnosed asthmatic children.
Topics: Acetates; Administration, Inhalation; Adolescent; Asthma; Bone and Bones; Budesonide; Child; Child, Preschool; Cyclopropanes; Double-Blind Method; Female; Glucocorticoids; Humans; Male; Parathyroid Hormone; Phosphorus; Quinolines; Sulfides | 2011 |
Effects of montelukast on patients with asthma after experimental inoculation with human rhinovirus 16.
Topics: Acetates; Asthma; Common Cold; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Pilot Projects; Quinolines; Respiratory Function Tests; Reverse Transcriptase Polymerase Chain Reaction; Rhinovirus; RNA, Viral; Sulfides; Young Adult | 2011 |
Anti-inflammatory properties of montelukast, a leukotriene receptor antagonist in patients with asthma and nasal polyposis.
Topics: Acetates; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Asthma, Aspirin-Induced; Cell Count; Cyclopropanes; Cysteine; Eosinophils; Female; Humans; Leukotriene Antagonists; Leukotrienes; Male; Middle Aged; Nasal Lavage Fluid; Nasal Polyps; Neurokinin A; Quinolines; Substance P; Sulfides; Treatment Outcome | 2011 |
Influence of leukotriene pathway polymorphisms on clinical responses to montelukast in Japanese patients with asthma.
Topics: Acetates; Adult; Aged; Alleles; Anti-Asthmatic Agents; Arachidonate 5-Lipoxygenase; Asian People; Asthma; Cyclopropanes; Epoxide Hydrolases; Female; Forced Expiratory Volume; Genotype; Humans; Japan; Leukotriene Antagonists; Leukotrienes; Male; Middle Aged; Peak Expiratory Flow Rate; Polymorphism, Single Nucleotide; Quinolines; Sequence Analysis, DNA; Sulfides; Treatment Outcome | 2012 |
The efficacy and tolerability of inhaled montelukast plus inhaled mometasone compared with mometasone alone in patients with chronic asthma.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Chronic Disease; Confidence Intervals; Cross-Over Studies; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Linear Models; Male; Maximum Tolerated Dose; Middle Aged; Mometasone Furoate; Patient Compliance; Pregnadienediols; Quinolines; Reference Values; Risk Assessment; Severity of Illness Index; Spirometry; Sulfides; Treatment Outcome; United States; Young Adult | 2011 |
Intermittent or daily montelukast versus placebo for episodic asthma in children.
Topics: Acetates; Administration, Oral; Anti-Asthmatic Agents; Asthma; Child, Preschool; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Female; Humans; Infant; Male; Placebos; Quinolines; Sulfides; Treatment Outcome | 2011 |
CYP2C8 but not CYP3A4 is important in the pharmacokinetics of montelukast.
Topics: 14-alpha Demethylase Inhibitors; Acetates; Adult; Anti-Asthmatic Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cross-Over Studies; Cyclopropanes; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Drug Interactions; Female; Gemfibrozil; Humans; Hypolipidemic Agents; Itraconazole; Male; Quinolines; Sulfides; Young Adult | 2012 |
Time-effect of montelukast on protection against exercise-induced bronchoconstriction.
Topics: Acetates; Asthma, Exercise-Induced; Bronchoconstriction; Child; Cross-Over Studies; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Exercise Test; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides; Time Factors | 2011 |
Neutrophil predominance in induced sputum from asthmatic patients. Therapeutic implications and role of clara cell 16-KD protein.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Budesonide; Cell Count; Cyclopropanes; Drug Therapy, Combination; Eosinophils; Female; Humans; Male; Neutrophils; Quinolines; Severity of Illness Index; Single-Blind Method; Sputum; Sulfides; Uteroglobin; Young Adult | 2011 |
The effect of montelukast on bronchial hyperreactivity and lung function in asthmatic children aged 6-13 years.
Topics: Acetates; Adolescent; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Cyclopropanes; Disease Progression; Female; Humans; Leukotriene Antagonists; Lung; Male; Quinolines; Respiratory Function Tests; Sulfides; Thailand; Treatment Outcome | 2011 |
Add-on montelukast in antihistamine-resistant chronic idiopathic urticaria.
Topics: Acetates; Chronic Disease; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Middle Aged; Quinolines; Sulfides; Surveys and Questionnaires; Treatment Outcome; Urticaria | 2011 |
Risk factors for montelukast treatment failure in step-down therapy for controlled asthma.
Topics: Acetates; Administration, Inhalation; Age of Onset; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Double-Blind Method; Forced Expiratory Volume; Glucocorticoids; Humans; Logistic Models; Quinolines; Risk Factors; Sensitivity and Specificity; Sulfides; Treatment Failure | 2011 |
Comparison of montelukast and mometasone furoate in the prevention of recurrent nasal polyps.
Topics: Acetates; Administration, Intranasal; Adult; Aged; Anti-Inflammatory Agents; Cyclopropanes; Endoscopy; Eosinophils; Ethmoid Sinus; Female; Follow-Up Studies; Humans; Leukotriene Antagonists; Male; Middle Aged; Mometasone Furoate; Nasal Polyps; Nasal Sprays; Pregnadienediols; Prospective Studies; Quinolines; Secondary Prevention; Sphenoid Sinus; Sulfides; Tomography, X-Ray Computed; Treatment Outcome | 2012 |
[Effect of montelukast sodium on TGF-beta(1) of peripheral blood mononuclear cells from children with mild persistent asthma].
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Female; Humans; Male; Quinolines; Single-Blind Method; Sulfides; T-Lymphocytes, Regulatory; Transforming Growth Factor beta1 | 2011 |
RCT of montelukast as prophylaxis for upper respiratory tract infections in children.
Topics: Acetates; Administration, Oral; Ambulatory Care Facilities; Anti-Asthmatic Agents; Child, Preschool; Cross-Sectional Studies; Cyclopropanes; Double-Blind Method; Female; Humans; Infant; Israel; Male; Quinolines; Respiratory Tract Infections; Sulfides | 2012 |
Bioequivalence studies of film-coated tablet and chewable tablet generic formulations of montelukast in healthy volunteers.
Topics: Acetates; Adult; Analysis of Variance; Anti-Asthmatic Agents; Area Under Curve; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cross-Over Studies; Cyclopropanes; Drugs, Generic; Female; Humans; Male; Middle Aged; Quinolines; Sulfides; Tablets; Tablets, Enteric-Coated; Tandem Mass Spectrometry; Therapeutic Equivalency; Young Adult | 2011 |
Effect of clarithromycin and fluconazole on the pharmacokinetics of montelukast in human volunteers.
Topics: Acetates; Administration, Oral; Adult; Analysis of Variance; Anti-Asthmatic Agents; Anti-Bacterial Agents; Antifungal Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Biotransformation; Chromatography, High Pressure Liquid; Clarithromycin; Cross-Over Studies; Cyclopropanes; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Administration Schedule; Drug Interactions; Egypt; Enzyme Inhibitors; Fluconazole; Half-Life; Humans; Leukotriene Antagonists; Male; Membrane Transport Modulators; Membrane Transport Proteins; Metabolic Clearance Rate; Models, Biological; Quinolines; Sulfides | 2012 |
Relative bioavailability of two 5-mg montelukast sodium chewable tablets: a single dose, randomized, open-label, 2-period crossover comparison in healthy korean adult male volunteers.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Area Under Curve; Asian People; Biological Availability; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cross-Over Studies; Cyclopropanes; Drugs, Generic; Half-Life; Humans; Male; Mass Spectrometry; Quinolines; Reproducibility of Results; Sulfides; Tablets; Young Adult | 2012 |
The effect of montelukast, budesonide alone, and in combination on exercise-induced bronchoconstriction.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Anti-Asthmatic Agents; Asthma, Exercise-Induced; Budesonide; Child; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukotriene Antagonists; Male; Placebos; Quinolines; Receptors, Leukotriene; Signal Transduction; Sulfides | 2012 |
Montelukast as an add-on therapy to inhaled corticosteroids in the treatment of severe asthma in elderly patients.
Topics: Acetates; Administration, Inhalation; Age Factors; Aged; Aged, 80 and over; Albuterol; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Budesonide; Chi-Square Distribution; Cyclopropanes; Drug Therapy, Combination; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Salmeterol Xinafoate; Spirometry; Sulfides; Surveys and Questionnaires | 2012 |
The efficacy and tolerability of intravenous montelukast in acute asthma exacerbations in Japanese patients.
Topics: Acetates; Adolescent; Adult; Aged; Anti-Asthmatic Agents; Asian People; Asthma; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Infusions, Intravenous; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Sulfides; Treatment Outcome; Young Adult | 2012 |
Montelukast effects on inflammation in allergic rhinitis: a double blind placebo controlled pilot study.
Topics: Acetates; Adult; Cell Count; Cyclopropanes; Double-Blind Method; Eosinophils; Female; Humans; Hypersensitivity; Inflammation; Leukotriene Antagonists; Lymphocytes; Macrophages; Male; Neutrophils; Pilot Projects; Quinolines; Rhinitis, Allergic, Perennial; Sulfides | 2012 |
Add-on montelukast vs double-dose budesonide in nonasthmatic eosinophilic bronchitis: a pilot study.
Topics: Acetates; Adult; Aged; Bronchitis; Bronchodilator Agents; Budesonide; Chronic Disease; Cough; Cyclopropanes; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Middle Aged; Pilot Projects; Pulmonary Eosinophilia; Quinolines; Sulfides; Treatment Outcome; Young Adult | 2012 |
Montelukast for children with obstructive sleep apnea: a double-blind, placebo-controlled study.
Topics: Acetates; Adenoids; Administration, Oral; Child; Child, Preschool; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Nasopharynx; Polysomnography; Quinolines; Sleep Apnea, Obstructive; Sulfides | 2012 |
The effect of montelukast on respiratory symptoms and lung function in wheezy infants.
Topics: Acetates; Anti-Asthmatic Agents; Bronchial Provocation Tests; Child, Preschool; Cyclopropanes; Female; Humans; Infant; Inflammation; Lung; Male; Nitric Oxide; Plethysmography; Quinolines; Respiration; Respiratory Function Tests; Respiratory Sounds; Sulfides; Treatment Outcome | 2013 |
Tailored second-line therapy in asthmatic children with the Arg(16) genotype.
Topics: Acetates; Adolescent; Adrenergic beta-2 Receptor Agonists; Albuterol; Amino Acid Motifs; Anti-Asthmatic Agents; Arginine; Asthma; Child; Child, Preschool; Cyclopropanes; Drug Therapy, Combination; Female; Genotype; Humans; Male; Polymorphism, Genetic; Quinolines; Receptors, Adrenergic, beta-2; Salmeterol Xinafoate; Sulfides | 2013 |
Implementation strategies of internet-based asthma self-management support in usual care. Study protocol for the IMPASSE cluster randomized trial.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Clinical Protocols; Cost-Benefit Analysis; Cyclopropanes; Female; Glucocorticoids; Health Status; Humans; Information Dissemination; Internet; Male; Medication Adherence; Middle Aged; Patient Education as Topic; Quality of Life; Quinolines; Randomized Controlled Trials as Topic; Self Care; Single-Blind Method; Sulfides; Young Adult | 2012 |
Management of Asthma in School age Children On Therapy (MASCOT): a randomised, double-blind, placebo-controlled, parallel study of efficacy and safety.
Topics: Absenteeism; Acetates; Adolescent; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Child; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Fluticasone; Humans; Male; Quality of Life; Quinolines; Salmeterol Xinafoate; Sulfides; United Kingdom | 2013 |
Effect of montelukast for treatment of asthma in cigarette smokers.
Topics: Acetates; Adolescent; Adult; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Fluticasone; Humans; Male; Middle Aged; Quinolines; Smoking; Sulfides; Young Adult | 2013 |
Formulation and in vitro and in vivo evaluation of film-coated montelukast sodium tablets using Opadry® yellow 20A82938 on an industrial scale.
Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Chromatography, High Pressure Liquid; Coloring Agents; Cross-Over Studies; Cyclopropanes; Drug Compounding; Drug Stability; Humans; Quinolines; Reproducibility of Results; Sodium Dodecyl Sulfate; Solubility; Sulfides; Tablets; Therapeutic Equivalency; Young Adult | 2013 |
Bioequivalence study of montelukast tablets in healthy Pakistani volunteers.
Topics: Acetates; Administration, Oral; Adult; Analysis of Variance; Anti-Asthmatic Agents; Area Under Curve; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cross-Over Studies; Cyclopropanes; Half-Life; Humans; Least-Squares Analysis; Leukotriene Antagonists; Male; Metabolic Clearance Rate; Models, Biological; Pakistan; Quinolines; Spectrophotometry, Ultraviolet; Sulfides; Tablets; Therapeutic Equivalency; Young Adult | 2013 |
A randomized, double-blind, placebo-controlled trial of oral montelukast in acute asthma exacerbation.
Topics: Acetates; Acute Disease; Administration, Oral; Adult; Aged; Asthma; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Lung; Male; Middle Aged; Peak Expiratory Flow Rate; Placebos; Quinolines; Recovery of Function; Sulfides; Treatment Outcome | 2013 |
Effects of 24-week add-on treatment with ciclesonide and montelukast on small airways inflammation in asthma.
Topics: Acetates; Aged; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Cell Count; Cell Movement; Cyclopropanes; Drug Therapy, Combination; Eosinophils; Female; Humans; Male; Middle Aged; Nitric Oxide; Pregnenediones; Pulmonary Alveoli; Quinolines; Respiratory Function Tests; Sulfides | 2013 |
[Bioequivalence study of montelukast 5 mg chewable tablets].
Topics: Acetates; Adolescent; Adult; Biological Availability; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cross-Over Studies; Cyclopropanes; Drugs, Generic; Female; Humans; Intestinal Absorption; Male; Middle Aged; Molecular Structure; Quinolines; Sulfides; Tablets; Therapeutic Equivalency; Young Adult | 2012 |
Desloratadine-montelukast combination improves quality of life and decreases nasal obstruction in patients with perennial allergic rhinitis.
Topics: Acetates; Adult; Cyclopropanes; Drug Combinations; Female; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Nasal Obstruction; Quality of Life; Quinolines; Rhinitis, Allergic, Perennial; Sulfides; Treatment Outcome; Young Adult | 2013 |
Bioequivalence studies for two different strengths of montelukast in healthy volunteers: 10 mg film-coated tablets and 5 mg chewable tablets.
Topics: Acetates; Adult; Cross-Over Studies; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Sulfides; Tablets; Therapeutic Equivalency | 2013 |
Montelukast improves air trapping, not airway remodeling, in patients with moderate-to-severe asthma: a pilot study.
Topics: Acetates; Adult; Airway Remodeling; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Middle Aged; Pilot Projects; Quinolines; Sulfides; Total Lung Capacity | 2013 |
The effect of montelukast on wheal reactions in skin prick tests: a double-blind-placebo-controlled randomized trial.
Topics: Acetates; Allergens; Animals; Asthma; Chi-Square Distribution; Child; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Pyroglyphidae; Quinolines; Reference Values; Rhinitis, Allergic; Rhinitis, Allergic, Perennial; Sensitivity and Specificity; Skin Tests; Statistics, Nonparametric; Sulfides; Terfenadine; Urticaria | 2013 |
Effect of combination of montelukast and levocetirizine on otitis media with effusion: a prospective, placebo-controlled trial.
Topics: Acetates; Administration, Oral; Cetirizine; Child; Child, Preschool; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Male; Otitis Media with Effusion; Otoscopy; Prospective Studies; Quinolines; Sulfides; Treatment Outcome | 2013 |
Hyperpolarized Helium-3 MRI of exercise-induced bronchoconstriction during challenge and therapy.
Topics: Acetates; Adult; Bronchial Diseases; Bronchodilator Agents; Constriction, Pathologic; Cyclopropanes; Exercise Test; Female; Helium; Humans; Isotopes; Lung Volume Measurements; Magnetic Resonance Imaging; Male; Middle Aged; Quinolines; Radiopharmaceuticals; Sulfides; Treatment Outcome; Young Adult | 2014 |
Predictors of asthma control and lung function responsiveness to step 3 therapy in children with uncontrolled asthma.
Topics: Acetates; Adolescent; Adrenergic beta-Agonists; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Biomarkers; Bronchodilator Agents; Child; Cross-Over Studies; Cyclopropanes; Eosinophils; Female; Fluticasone; Forced Expiratory Volume; Humans; Leukocyte Count; Leukotriene Antagonists; Leukotriene E4; Male; Quinolines; Salmeterol Xinafoate; Sulfides; Vital Capacity | 2014 |
Childhood asthma clusters and response to therapy in clinical trials.
Topics: Acetates; Adolescent; Adrenergic beta-2 Receptor Agonists; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Child; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Combinations; Female; Fluticasone; Fluticasone-Salmeterol Drug Combination; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2014 |
Budesonide inhalation suspension versus montelukast in children aged 2 to 4 years with mild persistent asthma.
Topics: Acetates; Administration, Inhalation; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Budesonide; Child, Preschool; Cyclopropanes; Drug Administration Schedule; Female; Humans; Male; Quinolines; Sulfides; Suspensions; Treatment Outcome | 2013 |
Wheal and flare reactions in skin prick tests of patients treated with montelukast alone or in combination with antihistamines.
Topics: Acetates; Adolescent; Adult; Aged; Antigens; Antigens, Dermatophagoides; Cetirizine; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Histamine Antagonists; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Prospective Studies; Quinolines; Rhinitis, Allergic, Perennial; Skin; Skin Tests; Sulfides; Young Adult | 2014 |
Add-on therapy with montelukast in the treatment of Henoch-Schönlein purpura.
Topics: Acetates; Child; Cyclopropanes; Double-Blind Method; Female; Humans; IgA Vasculitis; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2014 |
Sensitive LC-MS/MS-ESI method for simultaneous determination of montelukast and fexofenadine in human plasma: application to a bioequivalence study.
Topics: Acetates; Adult; Chromatography, High Pressure Liquid; Cross-Over Studies; Cyclopropanes; Drug Stability; Humans; Linear Models; Male; Quinolines; Reproducibility of Results; Sensitivity and Specificity; Single-Blind Method; Spectrometry, Mass, Electrospray Ionization; Sulfides; Tandem Mass Spectrometry; Terfenadine; Therapeutic Equivalency | 2014 |
Montelukast for postinfectious cough in adults: a double-blind randomised placebo-controlled trial.
Topics: Acetates; Adolescent; Adult; Analysis of Variance; Cough; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Quality of Life; Quinolines; Respiratory Tract Infections; Sulfides; Treatment Outcome; Young Adult | 2014 |
Leukotriene D4 inhalation challenge for predicting short-term efficacy of montelukast: a pilot study.
Topics: Acetates; Administration, Inhalation; Adult; Asthma; Bronchial Provocation Tests; Cyclopropanes; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Leukotriene D4; Male; Middle Aged; Pilot Projects; Predictive Value of Tests; Quality of Life; Quinolines; Sulfides; Treatment Outcome; Young Adult | 2015 |
Beneficial role for supplemental vitamin D3 treatment in chronic urticaria: a randomized study.
Topics: Acetates; Adult; Aged; Cetirizine; Cholecalciferol; Chronic Disease; Cyclopropanes; Dietary Supplements; Disease Progression; Female; Humans; Male; Middle Aged; Prospective Studies; Quinolines; Ranitidine; Sulfides; Urticaria; Young Adult | 2014 |
Montelukast versus budesonide as a first line preventive therapy in mild persistent asthma in 2 to 18 y.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Budesonide; Child; Child, Preschool; Cyclopropanes; Female; Humans; Male; Prospective Studies; Quinolines; Severity of Illness Index; Sulfides | 2014 |
Quality of life assessment in patients with moderate to severe allergic rhinitis treated with montelukast and/or intranasal steroids: a randomised, double-blind, placebo-controlled study.
Topics: Acetates; Administration, Intranasal; Adolescent; Adult; Androstadienes; Anti-Allergic Agents; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Fluticasone; Follow-Up Studies; Glucocorticoids; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Male; Middle Aged; Outcome Assessment, Health Care; Prospective Studies; Quality of Life; Quinolines; Rhinitis, Allergic, Seasonal; Severity of Illness Index; Sulfides; Surveys and Questionnaires; Treatment Outcome | 2014 |
Pulmonary function assessment in mild to moderate persistent asthma patients receiving montelukast, doxofylline, and tiotropium with budesonide: a randomized controlled study.
Topics: Acetates; Adult; Asthma; Bronchodilator Agents; Budesonide; Cyclopropanes; Drug Therapy, Combination; Female; Forced Expiratory Volume; Formoterol Fumarate; Humans; Male; Middle Aged; Quinolines; Respiratory Function Tests; Sulfides; Theophylline; Tiotropium Bromide | 2014 |
The effects of a Gly16Arg ADRB2 polymorphism on responses to salmeterol or montelukast in Japanese patients with mild persistent asthma.
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Adult; Albuterol; Asthma; Cyclopropanes; Female; Genotype; Humans; Male; Middle Aged; Polymorphism, Genetic; Quinolines; Receptors, Adrenergic, beta-2; Salmeterol Xinafoate; Sulfides | 2014 |
Clinical efficacy of montelukast sodium in treating infantile wheezing.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Case-Control Studies; Cyclopropanes; Female; Humans; Infant; Male; Prospective Studies; Quinolines; Respiratory Sounds; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Sulfides; Treatment Outcome | 2014 |
Eczema and race as combined determinants for differential response to step-up asthma therapy.
Topics: Acetates; Adolescent; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Black or African American; Child; Cross-Over Studies; Cyclopropanes; Drug Combinations; Drug Monitoring; Eczema; Female; Fluticasone; Fluticasone-Salmeterol Drug Combination; Hispanic or Latino; Humans; Male; Quinolines; Sulfides; White People | 2014 |
Effects of JNJ-40929837, a leukotriene A4 hydrolase inhibitor, in a bronchial allergen challenge model of asthma.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Bronchial Provocation Tests; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Epoxide Hydrolases; Female; Forced Expiratory Volume; Humans; Leukotriene B4; Male; Quinolines; Sputum; Sulfides; Thiazoles; Treatment Outcome; Tropanes; Young Adult | 2014 |
Leukotriene receptor blockade as a life-saving treatment in severe bronchopulmonary dysplasia.
Topics: Acetates; Bronchopulmonary Dysplasia; Cyclopropanes; Drug Dosage Calculations; Drug Monitoring; Female; Humans; Infant; Infant, Extremely Low Birth Weight; Infant, Newborn; Infant, Premature; Leukotriene Antagonists; Male; Prospective Studies; Quinolines; Radiography; Receptors, Leukotriene; Respiration, Artificial; Severity of Illness Index; Sulfides; Survival Rate; Treatment Outcome | 2014 |
Intermittent montelukast in children aged 10 months to 5 years with wheeze (WAIT trial): a multicentre, randomised, placebo-controlled trial.
Topics: Acetates; Anti-Asthmatic Agents; Appointments and Schedules; Arachidonate 5-Lipoxygenase; Asthma; Child, Preschool; Cyclopropanes; Cysteine; Drug Administration Schedule; Female; Genotype; Humans; Infant; Leukotrienes; Male; Quinolines; Respiratory Sounds; Sulfides; Treatment Outcome | 2014 |
Fluticasone or montelukast in preschool wheeze: a randomized controlled trial.
Topics: Acetates; Androstadienes; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Child, Preschool; Cyclopropanes; Female; Fluticasone; Humans; Infant; Male; Quinolines; Respiratory Sounds; Severity of Illness Index; Sulfides; Treatment Outcome | 2015 |
Efficacy of add-on montelukast in nonasthmatic eosinophilic bronchitis: the additive effect on airway inflammation, cough and life quality.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Bronchitis; Budesonide; Cough; Cyclopropanes; Female; Humans; Inflammation; Male; Middle Aged; Quality of Life; Quinolines; Sulfides; Young Adult | 2015 |
Assessment of montelukast, doxofylline, and tiotropium with budesonide for the treatment of asthma: which is the best among the second-line treatment? A randomized trial.
Topics: Acetates; Adolescent; Adult; Asthma; Bronchodilator Agents; Budesonide; Cyclopropanes; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Male; Quinolines; Respiratory Function Tests; Sulfides; Theophylline; Tiotropium Bromide | 2015 |
Do children with stable asthma benefit from addition of montelukast to inhaled corticosteroids: randomized, placebo controlled trial.
Topics: Acetates; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Animals; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Dose-Response Relationship, Drug; Drug Therapy, Combination; Exercise Test; Female; Humans; Hypersensitivity; Male; Nitric Oxide; Pyroglyphidae; Quinolines; Respiratory Function Tests; Severity of Illness Index; Sulfides | 2015 |
Characteristics of respiratory syncytial virus-induced bronchiolitis co-infection with Mycoplasma pneumoniae and add-on therapy with montelukast.
Topics: Acetates; Bronchiolitis; Coinfection; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Infant; Leukotriene Antagonists; Male; Pneumonia, Mycoplasma; Prospective Studies; Quinolines; Respiratory Syncytial Virus Infections; Sulfides | 2016 |
Does Montelukast Have an Effect on Post-tonsillectomy Pain Control in Children? A Randomized Trial Study.
Topics: Acetates; Administration, Oral; Adolescent; Analgesics; Child; Child, Preschool; Cyclopropanes; Double-Blind Method; Female; Humans; Male; Pain Measurement; Pain, Postoperative; Quinolines; Sulfides; Tablets; Tonsillectomy | 2015 |
Genome-wide association study of leukotriene modifier response in asthma.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cohort Studies; Cyclopropanes; Gene-Environment Interaction; Genetic Loci; Genome-Wide Association Study; Genotype; Humans; Hydroxyurea; Leukotrienes; Phenotype; Polymorphism, Single Nucleotide; Quinolines; Sulfides | 2016 |
Expression of leukotriene and its receptors in eosinophilic chronic rhinosinusitis with nasal polyps.
Topics: Acetates; Adult; Anti-Inflammatory Agents; Biomarkers; Blotting, Western; Budesonide; Case-Control Studies; Chronic Disease; Cyclopropanes; Drug Therapy, Combination; Eosinophils; Female; Humans; Leukotriene Antagonists; Leukotrienes; Male; Middle Aged; Nasal Polyps; Prospective Studies; Quinolines; Receptors, Leukotriene; Reverse Transcriptase Polymerase Chain Reaction; Rhinitis; Sinusitis; Sulfides; Treatment Outcome | 2016 |
Investigation of the bioequivalence of montelukast chewable tablets after a single oral administration using a validated LC-MS/MS method.
Topics: Acetates; Administration, Oral; Adolescent; Adult; Area Under Curve; Chemistry, Pharmaceutical; Chromatography, Liquid; Cross-Over Studies; Cyclopropanes; Drugs, Generic; Healthy Volunteers; Humans; Leukotriene Antagonists; Linear Models; Male; Mastication; Middle Aged; Models, Biological; Quinolines; Reproducibility of Results; Sulfides; Tablets; Tandem Mass Spectrometry; Therapeutic Equivalency; Young Adult | 2015 |
Roflumilast for asthma: Efficacy findings in non-placebo-controlled comparator and dosing studies.
Topics: Acetates; Adolescent; Adult; Aged; Aminopyridines; Asthma; Beclomethasone; Benzamides; Child; Cyclopropanes; Double-Blind Method; Forced Expiratory Volume; Humans; Middle Aged; Phosphodiesterase 4 Inhibitors; Quinolines; Sulfides; Young Adult | 2015 |
Fluticasone, Azithromycin, and Montelukast Treatment for New-Onset Bronchiolitis Obliterans Syndrome after Hematopoietic Cell Transplantation.
Topics: Acetates; Adult; Aged; Anti-Inflammatory Agents; Azithromycin; Bronchiolitis Obliterans; Cyclopropanes; Disease Progression; Fluticasone; Forced Expiratory Volume; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Lung; Male; Middle Aged; Quality of Life; Quinolines; Sulfides; Survival Analysis; Transplantation, Homologous; Treatment Outcome | 2016 |
[Clinical efficacy of montelukast for the treatment of bronchiolitis in infants].
Topics: Acetates; Bronchiolitis; Cyclopropanes; Humans; Infant; Leukotriene B4; Leukotriene E4; Quinolines; Sulfides | 2015 |
Roflumilast combined with montelukast versus montelukast alone as add-on treatment in patients with moderate-to-severe asthma.
Topics: Acetates; Aged; Aged, 80 and over; Aminopyridines; Anti-Asthmatic Agents; Asthma; Benzamides; Cyclopropanes; Disease Progression; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Leukocyte Count; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Risk Factors; Severity of Illness Index; Spirometry; Sulfides; Treatment Outcome | 2016 |
Montelukast as an add-on treatment in steroid dependant nephrotic syndrome, randomised-controlled trial.
Topics: Acetates; Adolescent; Child; Cyclopropanes; Drug Therapy, Combination; Female; Follow-Up Studies; Glucocorticoids; Humans; Kidney Function Tests; Leukotriene Antagonists; Male; Nephrotic Syndrome; Quinolines; Sulfides; Treatment Outcome | 2016 |
[Clinical evaluation of Montelukast plus Budesonide nasal spray and Desloratadine citrate disodium in treating moderate and severe persistent allergic rhinitis].
Topics: Acetates; Budesonide; Cyclopropanes; Humans; Loratadine; Nasal Sprays; Quinolines; Rhinitis, Allergic, Perennial; Sulfides; Surveys and Questionnaires | 2015 |
Montelukast for Children with Obstructive Sleep Apnea: Results of a Double-Blind, Randomized, Placebo-Controlled Trial.
Topics: Acetates; Anti-Inflammatory Agents; Child; Child, Preschool; Cyclopropanes; Double-Blind Method; Female; Humans; Kentucky; Leukotriene Antagonists; Male; Palatine Tonsil; Polysomnography; Prospective Studies; Quinolines; Sleep Apnea, Obstructive; Sulfides | 2016 |
Montelukast Does not Maintain Symptom Remission After Topical Steroid Therapy for Eosinophilic Esophagitis.
Topics: Acetates; Adolescent; Adult; Aged; Cyclopropanes; Cytochrome P-450 CYP1A2 Inducers; Double-Blind Method; Eosinophilic Esophagitis; Female; Humans; Leukotriene Antagonists; Maintenance Chemotherapy; Male; Middle Aged; Minnesota; Placebos; Prospective Studies; Quinolines; Steroids; Sulfides; Treatment Outcome; Young Adult | 2017 |
Fluctuation Analysis of Peak Expiratory Flow and Its Association with Treatment Failure in Asthma.
Topics: Acetates; Administration, Inhalation; Adult; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Cyclopropanes; Drug Therapy, Combination; Female; Fluticasone; Humans; Male; Peak Expiratory Flow Rate; Quinolines; Salmeterol Xinafoate; Sulfides; Treatment Failure | 2017 |
A randomized placebo-controlled trial of traditional Chinese medicine as an add-on therapy to oral montelukast in the treatment of mild persistent asthma in children.
Topics: Acetates; Adolescent; Asthma; Child; Cyclopropanes; Double-Blind Method; Drugs, Chinese Herbal; Female; Humans; Male; Medicine, Chinese Traditional; Quality of Life; Quinolines; Sulfides | 2016 |
Comparison of the effects of nasal steroids and montelukast on olfactory functions in patients with allergic rhinitis.
Topics: Acetates; Administration, Intranasal; Adolescent; Adult; Aged; Anti-Allergic Agents; Cyclopropanes; Glucocorticoids; Humans; Olfaction Disorders; Prospective Studies; Quinolines; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal; Sensory Thresholds; Smell; Sulfides; Treatment Outcome | 2017 |
Therapeutic Effect of Montelukast for Treatment of Uremic Pruritus in Hemodialysis Patients.
Topics: Acetates; Adult; C-Reactive Protein; Cyclopropanes; Drug Monitoring; Female; Humans; Kidney Failure, Chronic; Leukotriene Antagonists; Male; Middle Aged; Pruritus; Quinolines; Renal Dialysis; Sulfides; Treatment Outcome; Uremia | 2017 |
Clinical effect of montelukast sodium combined with inhaled corticosteroids in the treatment of OSAS children.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Cervical Vertebrae; Child, Preschool; Cyclopropanes; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Mometasone Furoate; Nasal Sprays; Polysomnography; Quinolines; Respiratory System Agents; Sleep Apnea, Obstructive; Sulfides; Surveys and Questionnaires; Treatment Outcome | 2017 |
Early control treatment with montelukast in preschool children with asthma: A randomized controlled trial.
Topics: Acetates; Adrenergic beta-2 Receptor Agonists; Asthma; Child, Preschool; Cyclopropanes; Female; Humans; Infant; Japan; Male; Quinolines; Registries; Sulfides | 2018 |
Montelukast Treatment of Acute Asthma Exacerbations in Children Aged 2 to 5 Years: A Randomized, Double-Blind, Placebo-Controlled Trial.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Child, Preschool; China; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Quinolines; Sulfides; Treatment Outcome | 2018 |
Effectiveness of montelukast in overweight and obese atopic asthmatics.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Double-Blind Method; Female; Humans; Male; Obesity; Overweight; Prospective Studies; Quinolines; Sulfides | 2017 |
Fevipiprant, an oral prostaglandin DP
Topics: Acetates; Adult; Airway Management; Anti-Asthmatic Agents; Asthma; Budesonide; Cyclopropanes; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Monitoring; Female; Forced Expiratory Volume; Glucocorticoids; Humans; Indoleacetic Acids; Male; Middle Aged; Pyridines; Quinolines; Receptors, Immunologic; Receptors, Prostaglandin; Severity of Illness Index; Sulfides; Treatment Outcome | 2017 |
The effect of montelukast on early-life wheezing: A randomized, double-blinded placebo-controlled study.
Topics: Acetates; Anti-Asthmatic Agents; Child, Preschool; Cyclopropanes; Double-Blind Method; Eicosanoids; Female; Humans; Infant; Male; Prospective Studies; Quinolines; Respiratory Sounds; Sulfides; Treatment Outcome | 2018 |
Lack of long-term add-on effect by montelukast in postoperative chronic rhinosinusitis patients with nasal polyps.
Topics: Acetates; Administration, Intranasal; Adrenal Cortex Hormones; Adult; Aged; Chronic Disease; Cyclopropanes; Drug Therapy, Combination; Endoscopy; Female; Follow-Up Studies; Humans; Leukotriene Antagonists; Male; Middle Aged; Nasal Polyps; Paranasal Sinuses; Postoperative Period; Prospective Studies; Quinolines; Rhinitis; Sinusitis; Sulfides; Treatment Outcome | 2018 |
Clopidogrel but Not Prasugrel Significantly Inhibits the CYP2C8-Mediated Metabolism of Montelukast in Humans.
Topics: Acetates; Adult; Clopidogrel; Computer Simulation; Cross-Over Studies; Cyclopropanes; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C8 Inhibitors; Drug Interactions; Female; Healthy Volunteers; Humans; Inactivation, Metabolic; Leukotriene Antagonists; Male; Models, Biological; Oxidation-Reduction; Pharmacogenetics; Pharmacogenomic Variants; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Quinolines; Risk Assessment; Substrate Specificity; Sulfides; Young Adult | 2018 |
[Micro-invasive embedding combined with montelukast sodium for children cough variant asthma:a randomized controlled trial].
Topics: Acetates; Acupuncture Points; Acupuncture Therapy; Anti-Asthmatic Agents; Asthma; Child; Cough; Cyclopropanes; Forced Expiratory Volume; Humans; Quinolines; Sulfides | 2017 |
Evaluation of the effects of montelukast, mometasone furoate, and combined therapyon adenoid size: a randomized, prospective, clinical trial with objective data
Topics: Acetates; Adenoids; Administration, Intranasal; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Child; Child, Preschool; Cyclopropanes; Drug Therapy, Combination; Female; Humans; Hypertrophy; Male; Mometasone Furoate; Nasal Obstruction; Prospective Studies; Quinolines; Recurrence; Sulfides; Treatment Outcome | 2017 |
Traditional Chinese medicine as an adjunctive therapy to oral montelukast for treating patients with chronic asthma.
Topics: Acetates; Administration, Oral; Adolescent; Adult; Asthma; China; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Follow-Up Studies; Hospitals, University; Humans; Male; Medicine, Chinese Traditional; Middle Aged; Quality of Life; Quinolines; Respiratory Function Tests; Risk Assessment; Statistics, Nonparametric; Sulfides; Treatment Outcome; Young Adult | 2017 |
Efficacy and safety of lebrikizumab in adult patients with mild-to-moderate asthma not receiving inhaled corticosteroids.
Topics: Acetates; Administration, Inhalation; Adult; Anti-Asthmatic Agents; Antibodies, Monoclonal; Asthma; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Glucocorticoids; Humans; Injections, Subcutaneous; Male; Middle Aged; Quinolines; Severity of Illness Index; Sulfides; Treatment Failure; Treatment Outcome | 2018 |
Phenotyping patients with chronic cough: Evaluating the ability to predict the response to anti-inflammatory therapy.
Topics: Acetates; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Breath Tests; Chronic Disease; Cough; Cyclopropanes; Exhalation; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Nitric Oxide; Phenotype; Pilot Projects; Prednisolone; Quinolines; Sulfides; Treatment Outcome | 2018 |
Leukotriene E
Topics: Acetates; Adult; Aspirin; Asthma; Bronchoconstriction; Bronchoconstrictor Agents; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Eicosanoids; Female; Humans; Leukotriene Antagonists; Male; Mast Cells; Middle Aged; Quinolines; Receptors, Leukotriene; Sulfides; Young Adult | 2018 |
Montelukast for bronchiolitis obliterans syndrome after lung transplantation: A randomized controlled trial.
Topics: Acetates; Bronchiolitis Obliterans; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Graft Rejection; Humans; Leukotriene Antagonists; Lung; Lung Transplantation; Male; Middle Aged; Quinolines; Respiratory Function Tests; Sulfides; Survival Rate; Treatment Outcome | 2018 |
Seasonality of sputum eosinophilia in adolescents with asthma remission: effects of montelukast.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Eosinophilia; Female; Humans; Male; Poland; Prospective Studies; Quinolines; Seasons; Spirometry; Sputum; Sulfides | 2018 |
[Effect of nasal glucocorticoid combined with loratadine or montelukast on allergic rhinitis].
Topics: Acetates; Administration, Intranasal; Anti-Allergic Agents; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Glucocorticoids; Histamine Antagonists; Humans; Leukotriene Antagonists; Loratadine; Mometasone Furoate; Quinolines; Rhinitis, Allergic; Sulfides; Treatment Outcome | 2017 |
A Randomized, Multicenter, Double-blind, Phase III Study to Evaluate the Efficacy on Allergic Rhinitis and Safety of a Combination Therapy of Montelukast and Levocetirizine in Patients With Asthma and Allergic Rhinitis.
Topics: Acetates; Adult; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Cetirizine; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Quinolines; Republic of Korea; Respiratory Function Tests; Rhinitis, Allergic, Perennial; Sulfides; Treatment Outcome | 2018 |
Comparison of the pharmacokinetics and tolerability of montelukast/levocetirizine administered as a fixed-dose combination and as separate tablets.
Topics: Acetates; Administration, Oral; Adult; Area Under Curve; Biological Availability; Cetirizine; Cross-Over Studies; Cyclopropanes; Drug Compounding; Half-Life; Healthy Volunteers; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Male; Metabolic Clearance Rate; Middle Aged; Quinolines; Republic of Korea; Sulfides; Tablets; Young Adult | 2018 |
Efficacy of montelukast as prophylactic treatment for seasonal allergic rhinitis.
Topics: Acetates; Adolescent; Adult; Allergens; Anti-Asthmatic Agents; Cyclopropanes; Female; Humans; Male; Middle Aged; Pollen; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides; Treatment Outcome; Young Adult | 2018 |
Combination therapy with montelukast and loratadine alleviates pharyngolaryngeal symptoms related to seasonal allergic rhinitis.
Topics: Acetates; Adolescent; Adult; Allergens; Anti-Allergic Agents; Cryptomeria; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Pollen; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides; Young Adult | 2019 |
Comparison of the efficacy and mechanisms of intranasal budesonide, montelukast, and their combination in treatment of patients with seasonal allergic rhinitis.
Topics: Acetates; Administration, Intranasal; Adolescent; Adult; Anti-Inflammatory Agents; Budesonide; Cyclopropanes; Drug Therapy, Combination; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides; Treatment Outcome; Young Adult | 2018 |
Results of an early access treatment protocol of daratumumab in United States patients with relapsed or refractory multiple myeloma.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Agents, Immunological; Cyclopropanes; Drug Administration Schedule; Drug Approval; Female; Humans; Infusions, Intravenous; Injection Site Reaction; Male; Middle Aged; Multiple Myeloma; Neoplasm Recurrence, Local; Quinolines; Sulfides; Survival Analysis; Treatment Outcome; United States | 2018 |
Exercise training as an adjunctive therapy to montelukast in children with mild asthma: A randomized controlled trial.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Combined Modality Therapy; Cyclopropanes; Exercise Therapy; Female; Follow-Up Studies; Humans; Male; Quinolines; Severity of Illness Index; Sulfides; Treatment Outcome | 2019 |
An Open-Label, Multi-Institutional, Randomized Study to Evaluate the Additive Effect of a Leukotriene Receptor Antagonist on Cough Score in Patients with Cough-Variant Asthma Being Treated with Inhaled Corticosteroids.
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Adult; Asthma; Cough; Cyclopropanes; Drug Therapy, Combination; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Sulfides | 2018 |
[Clinical effect of fluticasone propionate, montelukast sodium and ketotifen in treatment of cough variant asthma in children].
Topics: Acetates; Androstadienes; Anti-Asthmatic Agents; Asthma; Child; Cough; Cyclopropanes; Drug Combinations; Fluticasone; Humans; Ketotifen; Quinolines; Sulfides | 2019 |
Effect of montelukast combined with methylprednisolone for the treatment of mycoplasma pneumonia.
Topics: Acetates; Anti-Inflammatory Agents; Child; Child, Preschool; Cyclopropanes; Cytokines; Drug Therapy, Combination; Female; Humans; Leukotriene Antagonists; Male; Methylprednisolone; Pneumonia, Mycoplasma; Prognosis; Quinolines; Sulfides; T-Lymphocyte Subsets | 2019 |
Effects of Medical Therapy on Mild Obstructive Sleep Apnea in Adult Patients.
Topics: Acetates; Administration, Intranasal; Anti-Inflammatory Agents; Cyclopropanes; Double-Blind Method; Female; Fluticasone; Humans; Leukotriene Antagonists; Male; Middle Aged; Prospective Studies; Quinolines; Sleep Apnea, Obstructive; Sulfides; Treatment Outcome | 2019 |
Effect of cysteinyl leukotriene receptor 1 blockade on aeroallergen-induced nasal recruitment of CD49d expressing neutrophils.
Topics: Acetates; Adult; Air Pollutants; Allergens; Animals; Cyclopropanes; Double-Blind Method; Female; Humans; Hypersensitivity; Integrin alpha4; Leukotriene Antagonists; Male; Mice; Middle Aged; Nasal Lavage Fluid; Neutrophils; Quinolines; Receptors, Leukotriene; Sulfides; Young Adult | 2019 |
Efficacy of montelukast sodium chewable tablets combined with inhaled budesonide in treating pediatric asthma and its effect on inflammatory factors.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Anti-Asthmatic Agents; Asthma; Budesonide; Child; Child, Preschool; Cyclopropanes; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Inflammation; Male; Quinolines; Respiratory Function Tests; Sulfides; Tablets; Treatment Outcome | 2019 |
A Randomized Trial of Comparing a Combination of Montelukast and Budesonide With Budesonide in Allergic Rhinitis.
Topics: Acetates; Administration, Intranasal; Adult; Bronchodilator Agents; Budesonide; China; Cyclopropanes; Drug Therapy, Combination; Female; Humans; Leukotriene Antagonists; Male; Nasal Obstruction; Quinolines; Rhinitis, Allergic; Sulfides | 2021 |
Developmental Pharmacogenetics of SLCO2B1 on Montelukast Pharmacokinetics in Chinese Children.
Topics: Acetates; Asthma; Child; Child, Preschool; China; Cyclopropanes; Female; Genotype; Humans; Infant; Leukotriene Antagonists; Male; Organic Anion Transporters; Pharmacogenetics; Prospective Studies; Quinolines; Receptors, Leukotriene; Sulfides | 2019 |
Phase 2 trial of montelukast for prevention of pain in sickle cell disease.
Topics: Acetates; Adolescent; Adult; Anemia, Sickle Cell; Cyclopropanes; Humans; Leukotriene Antagonists; Pain; Quinolines; Sulfides | 2020 |
Comparative pharmacokinetics of a montelukast/levocetirizine fixed-dose combination chewable tablet versus individual administration of montelukast and levocetirizine after a single oral administration in healthy Korean male subjects
.
Topics: Acetates; Administration, Oral; Area Under Curve; Cetirizine; Cross-Over Studies; Cyclopropanes; Drug Combinations; Healthy Volunteers; Humans; Male; Quinolines; Republic of Korea; Sulfides; Tablets; Therapeutic Equivalency | 2020 |
The efficacy of a leukotriene receptor antagonist in the treatment of human rectal aberrant crypt foci: a nonrandomized, open-label, controlled trial.
Topics: Aberrant Crypt Foci; Acetates; Administration, Oral; Adult; Aged; Aged, 80 and over; Biopsy; Cell Proliferation; Colon; Colonic Polyps; Colonoscopy; Controlled Clinical Trials as Topic; Cyclopropanes; Female; Humans; Intestinal Mucosa; Leukotriene Antagonists; Male; Middle Aged; Pilot Projects; Prospective Studies; Quinolines; Rectum; Sulfides; Treatment Outcome | 2020 |
Efficacy of Chinese Medicine Acupoint Application Combined with Montelukast on Children with Perennial Allergic Rhinitis: A Randomized Controlled Trial.
Topics: Acetates; Acupuncture Points; Administration, Topical; Child; Child, Preschool; Cyclopropanes; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Humans; Male; Prospective Studies; Quinolines; Rhinitis, Allergic, Perennial; Single-Blind Method; Sulfides | 2020 |
Comparison of Outcomes Between Mometasone Furoate Intranasal Spray and Oral Montelukast in Patients with Allergic Rhinitis.
Topics: Acetates; Anti-Allergic Agents; Cyclopropanes; Humans; Mometasone Furoate; Nepal; Pregnadienediols; Prospective Studies; Quinolines; Rhinitis, Allergic; Sulfides; Treatment Outcome | 2020 |
Pharmacokinetics and Bioequivalence Evaluation of Two Montelukast Sodium Chewable Tablets in Healthy Chinese Volunteers Under Fasted and Fed Conditions.
Topics: Acetates; Administration, Oral; Adolescent; Adult; Asian People; Cross-Over Studies; Cyclopropanes; Drug Compounding; Fasting; Female; Healthy Volunteers; Humans; Male; Middle Aged; Quinolines; Sulfides; Tablets; Therapeutic Equivalency; Young Adult | 2021 |
Effects of using montelukast during acute wheezing attack in hospitalized preschool children on the discharge rate and the clinical asthma score.
Topics: Acetates; Asthma; Child; Child, Preschool; Cyclopropanes; Double-Blind Method; Humans; Infant; Leukotriene Antagonists; Patient Discharge; Quinolines; Respiratory Sounds; Sulfides | 2021 |
Efficacy of montelukast in preventing seasonal recurrence of vernal keratoconjunctivitis in children.
Topics: Acetates; Child; Conjunctivitis, Allergic; Cyclopropanes; Humans; Ophthalmic Solutions; Prospective Studies; Pruritus; Quinolines; Seasons; Sulfides; Treatment Outcome | 2022 |
The leukotriene receptor antagonist montelukast in the treatment of non-alcoholic steatohepatitis: A proof-of-concept, randomized, double-blind, placebo-controlled trial.
Topics: Acetates; Adult; Biomarkers; Cyclopropanes; Double-Blind Method; Elasticity Imaging Techniques; Female; Humans; Leukotriene Antagonists; Liver; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Placebos; Proof of Concept Study; Prospective Studies; Quinolines; Sulfides; Treatment Outcome | 2021 |
Comparative study evaluating antihistamine versus leukotriene receptor antagonist as adjuvant therapy for rheumatoid arthritis.
Topics: Acetates; Adult; Arthritis, Rheumatoid; Body Mass Index; C-Reactive Protein; Clusterin; Cyclopropanes; Cyproheptadine; Double-Blind Method; Drug Therapy, Combination; E-Selectin; Egypt; Female; Histamine Antagonists; Humans; Immunosuppressive Agents; Interleukins; Leukotriene Antagonists; Male; Methotrexate; Middle Aged; Quinolines; Sulfides | 2021 |
Bioavailability assessment of fexofenadine and montelukast in a fixed-dose combination tablet
Topics: Acetates; Area Under Curve; Biological Availability; Cross-Over Studies; Cyclopropanes; Humans; Quinolines; Rhinitis, Allergic; Sulfides; Tablets; Terfenadine | 2021 |
What Is the Effect of Pre-Emptive Oral Montelukast on Postoperative Pain Following Bimaxillary Orthognathic Surgery? A Triple-Blind Randomized Clinical Trial.
Topics: Acetates; Adult; Analgesics, Opioid; Cyclopropanes; Double-Blind Method; Female; Humans; Male; Orthognathic Surgery; Pain, Postoperative; Quinolines; Sulfides; Young Adult | 2022 |
Study of montelukast in children with sickle cell disease (SMILES): a study protocol for a randomised controlled trial.
Topics: Acetates; Anemia, Sickle Cell; Anti-Inflammatory Agents; Child; Child, Preschool; Cyclopropanes; Humans; Quinolines; Randomized Controlled Trials as Topic; Sulfides | 2021 |
Efficacy, tolerability, and safety of montelukast versus finasteride for the treatment of moderate acne in women: A prospective, randomized, single-blinded, active-controlled trial.
Topics: Acetates; Acne Vulgaris; Cyclopropanes; Female; Finasteride; Humans; Prospective Studies; Quinolines; Sulfides | 2021 |
Effect of montelukast therapy on clinical course, pulmonary function, and mortality in patients with COVID-19.
Topics: Acetates; COVID-19 Drug Treatment; Cyclopropanes; Humans; Prospective Studies; Quinolines; SARS-CoV-2; Sulfides | 2022 |
Double-blind placebo-controlled randomized clinical trial to assess the efficacy of montelukast in mild to moderate respiratory symptoms of patients with long COVID: E-SPERANZA COVID Project study protocol.
Topics: Acetates; COVID-19; Cyclopropanes; Double-Blind Method; Humans; Oxygen Saturation; Post-Acute COVID-19 Syndrome; Quality of Life; Quinolines; Randomized Controlled Trials as Topic; SARS-CoV-2; Sulfides; Treatment Outcome | 2022 |
MOntelukast as a potential CHondroprotective treatment following Anterior cruciate ligament reconstruction (MOCHA Trial): study protocol for a double-blind, randomized, placebo-controlled clinical trial.
Topics: Acetates; Adult; Anterior Cruciate Ligament Reconstruction; Cyclopropanes; Humans; Middle Aged; Multicenter Studies as Topic; Quinolines; Randomized Controlled Trials as Topic; Sulfides | 2022 |
Prospective Phase II Trial of Montelukast to Treat Bronchiolitis Obliterans Syndrome after Hematopoietic Cell Transplantation and Investigation into Bronchiolitis Obliterans Syndrome Pathogenesis.
Topics: Acetates; Bronchiolitis Obliterans; Cyclopropanes; Hematopoietic Stem Cell Transplantation; Humans; Prospective Studies; Quinolines; Sulfides; Syndrome | 2022 |
A Comparative Study of Montelukast and Azelastine add on Therapy in Moderate to Severe Allergic Rhinitis Treatment: A Double-Blind Randomized Clinical Trial.
Topics: Acetates; Administration, Intranasal; Adolescent; Adrenal Cortex Hormones; Adult; Asthma; Budesonide; Cyclopropanes; Double-Blind Method; Histamine Antagonists; Histamine H1 Antagonists; Humans; Nasal Sprays; Phthalazines; Quality of Life; Quinolines; Rhinitis, Allergic; Sulfides; Treatment Outcome; Young Adult | 2022 |
Addition of a nutraceutical to montelukast or inhaled steroid in the treatment of wheezing during COVID-19 pandemic: a multicenter, open-label, randomized controlled trial.
Topics: Acetates; Administration, Inhalation; Anti-Asthmatic Agents; Asthma; Child; Communicable Disease Control; COVID-19; Cyclopropanes; Dietary Supplements; Humans; Pandemics; Quinolines; Respiratory Sounds; Steroids; Sulfides | 2022 |
The effectiveness of gabapentin and gabapentin/montelukast combination compared with dextromethorphan in the improvement of COVID-19- related cough: A randomized, controlled clinical trial.
Topics: Acetates; Cough; COVID-19; COVID-19 Drug Treatment; Cyclopropanes; Dextromethorphan; Gabapentin; Humans; Quinolines; SARS-CoV-2; Sulfides; Treatment Outcome | 2022 |
Montelukast as an effective adjuvant in the treatment of moderate acne vulgaris.
Topics: Acetates; Acne Vulgaris; Anti-Bacterial Agents; Benzoyl Peroxide; Cyclopropanes; Dermatologic Agents; Double-Blind Method; Doxycycline; Gels; Humans; Immunoglobulin A; Leukotriene B4; Quinolines; Sulfides; Treatment Outcome | 2022 |
Effects of treatment with montelukast alone, budesonide/formoterol alone and a combination of both in cough variant asthma.
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Antitussive Agents; Asthma; Budesonide; Budesonide, Formoterol Fumarate Drug Combination; Capsaicin; Cough; Cyclopropanes; Formoterol Fumarate; Humans; Inflammation; Leukotriene Antagonists; Quinolines; Sulfides | 2022 |
Effect of budesonide combined with montelukast sodium on pulmonary function parameters and immunoglobulin levels in children with bronchial asthma.
Topics: Acetates; Administration, Inhalation; Anti-Asthmatic Agents; Asthma; Budesonide; Child; Humans; Quinolines | 2023 |
Montelukast Is Effective in Treating Rhabdomyolysis Due to Intoxication: A Randomized Clinical Trial.
Topics: Acetates; Adult; Creatinine; Cyclopropanes; Humans; Middle Aged; Single-Blind Method; Young Adult | 2023 |
1027 other study(ies) available for phenyl acetate and montelukast
| Article | Year |
|---|---|
Pharmacology of montelukast sodium (Singulair), a potent and selective leukotriene D4 receptor antagonist.
Topics: Acetates; Animals; Binding, Competitive; Cyclopropanes; Guinea Pigs; Leukotriene Antagonists; Leukotriene D4; Lung; Male; Mucous Membrane; Muscle Contraction; Muscle, Smooth; Quinolines; Rats; Rats, Inbred Strains; Receptors, Leukotriene; Respiratory System; Saimiri; Sheep; Sulfides | 1995 |
Determination of MK-0476 in human plasma by liquid chromatography.
Topics: Acetates; Chromatography, Liquid; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Sensitivity and Specificity; Sulfides | 1995 |
Development and validation of a general non-digestive method for the determination of palladium in bulk pharmaceutical chemicals and their synthetic intermediates by graphite furnace atomic absorption spectroscopy.
Topics: Acetates; Anticonvulsants; Chemistry, Pharmaceutical; Cyclohexylamines; Cyclopropanes; Enzyme Inhibitors; Graphite; Indoles; Linear Models; Nitric Acid; Palladium; Quinolines; Reproducibility of Results; Sensitivity and Specificity; Serotonin Receptor Agonists; Solvents; Spectrophotometry, Atomic; Sulfides; Triazoles; Tryptamines | 1997 |
Determination of montelukast (MK-0476) and its S-enantiomer in human plasma by stereoselective high-performance liquid chromatography with column-switching.
Topics: Acetates; Chromatography, High Pressure Liquid; Cyclopropanes; Humans; Leukotriene Antagonists; Membrane Proteins; Quinolines; Receptors, Leukotriene; Reproducibility of Results; Stereoisomerism; Sulfides | 1997 |
Hepatic microsomal metabolism of montelukast, a potent leukotriene D4 receptor antagonist, in humans.
Topics: Acetates; Adult; Child; Cyclopropanes; Cytochrome P-450 Enzyme System; Female; Humans; In Vitro Techniques; Male; Microsomes, Liver; Middle Aged; Monoamine Oxidase; Quinolines; Sulfides | 1997 |
A novel photoaffinity probe for the LTD4 receptor.
Topics: Acetates; Animals; Autoradiography; Azirines; Cyclopropanes; Guinea Pigs; Iodine Radioisotopes; Isotope Labeling; Leukotriene Antagonists; Lung; Membrane Proteins; Molecular Weight; Photoaffinity Labels; Quinolines; Receptors, Leukotriene; Sulfides | 1998 |
Montelukast (MK-0476)
Topics: Acetates; Anxiety; Asthma; Cyclopropanes; Headache; Humans; Leukotriene Antagonists; Quinolines; Sulfides; Vertigo | 1997 |
CGP57698: a structurally simple, highly potent peptido-leukotriene (pLT) antagonist of the quinoline type.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Bronchoconstriction; Cyclopropanes; Guinea Pigs; Indoles; Leukotriene Antagonists; Leukotriene D4; Lung; Molecular Structure; Muscle, Smooth; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 1997 |
Montelukast approved for asthma management.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Drug Approval; Humans; Quinolines; Sulfides; United States; United States Food and Drug Administration | 1998 |
[Montelukast--a new building block in the therapy of bronchial asthma. Introductory Symposium, MSD Sharp & Dohme GMBH. Telfs (Austria) 6-8 March 1998].
Topics: Acetates; Asthma; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 1998 |
New treatments for exercise-induced asthma.
Topics: Acetates; Adrenergic beta-Agonists; Albuterol; Anti-Asthmatic Agents; Asthma, Exercise-Induced; Bronchoconstriction; Cyclopropanes; Drug Tolerance; Humans; Leukotriene Antagonists; Quinolines; Salmeterol Xinafoate; Sulfides | 1998 |
Montelukast for persistent asthma.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Beclomethasone; Child; Clinical Trials as Topic; Cyclopropanes; Double-Blind Method; Drug Interactions; Fees, Pharmaceutical; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 1998 |
Exercise-induced asthma.
Topics: Acetates; Albuterol; Asthma, Exercise-Induced; Bronchodilator Agents; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Salmeterol Xinafoate; Sulfides | 1998 |
Determination of montelukast sodium in human plasma by column-switching high-performance liquid chromatography with fluorescence detection.
Topics: Acetates; Administration, Oral; Anti-Asthmatic Agents; Chromatography, High Pressure Liquid; Cyclopropanes; Humans; Leukotriene Antagonists; Male; Quinolines; Sensitivity and Specificity; Spectrometry, Fluorescence; Stereoisomerism; Sulfides; Ultraviolet Rays | 1998 |
Montelukast for children with asthma.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 1998 |
Montelukast for mild and exercise-induced asthma.
Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Asthma, Exercise-Induced; Cyclopropanes; Double-Blind Method; Humans; Leukotriene Antagonists; Middle Aged; Multicenter Studies as Topic; Quinolines; Randomized Controlled Trials as Topic; Reproducibility of Results; Sulfides; Treatment Outcome | 1998 |
Exercise-induced asthma.
Topics: Acetates; Adolescent; Adrenergic beta-Agonists; Adult; Anti-Asthmatic Agents; Asthma, Exercise-Induced; Child; Cyclopropanes; Forced Expiratory Volume; Humans; Quinolines; Sulfides | 1998 |
Exercise-induced asthma.
Topics: Acetates; Adrenergic beta-Agonists; Albuterol; Anti-Asthmatic Agents; Area Under Curve; Asthma, Exercise-Induced; Cold Temperature; Cyclopropanes; Forced Expiratory Volume; Humans; Humidity; Quinolines; Salmeterol Xinafoate; Sulfides | 1998 |
A series of non-quinoline cysLT1 receptor antagonists: SAR study on pyridyl analogs of Singulair.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Cyclopropanes; Guinea Pigs; Humans; Leukotriene Antagonists; Membrane Proteins; Pyridines; Quinolines; Rats; Receptors, Leukotriene; Saimiri; Structure-Activity Relationship; Sulfides | 1998 |
["Bronchial asthma--therapeutic advances due to leukotriene antagonists." Symposium: "Leukotriene antagonists: a therapeutic advance in the control of asthma." 30-31 October 1998, Copenhagen].
Topics: Acetates; Asthma; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 1998 |
Drugs for asthma.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adolescent; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Asthma; Bone Density; Bronchial Spasm; Bronchodilator Agents; Child; Child, Preschool; Choice Behavior; Cromolyn Sodium; Cyclopropanes; Exercise; Female; Growth; Humans; Hydroxyurea; Indoles; Infant, Newborn; Ipratropium; Lactation; Leukotriene Antagonists; Phenylcarbamates; Pregnancy; Pregnancy Complications; Quinolines; Salmeterol Xinafoate; Sulfides; Sulfonamides; Tachycardia; Theophylline; Tosyl Compounds | 1999 |
The emerging role of leukotriene antagonists in asthma therapy.
Topics: Acetates; Adrenergic beta-Agonists; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Glucocorticoids; Humans; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome | 1999 |
Leukotriene modifiers: new drugs, old and new reactions.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Autoimmune Diseases; Chromones; Churg-Strauss Syndrome; Cyclopropanes; Drug Hypersensitivity; Eosinophilia; Humans; Indoles; Leukotriene Antagonists; Leukotrienes; Lupus Erythematosus, Systemic; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Th2 Cells; Tosyl Compounds | 1999 |
A new-drug roundup.
Topics: Acetates; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antitubercular Agents; Antiviral Agents; Capecitabine; Cyclopropanes; Deoxycytidine; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Etanercept; Fluorouracil; Humans; Immunoglobulin G; Isoxazoles; Leflunomide; Phosphodiesterase Inhibitors; Piperazines; Purines; Quinolines; Receptors, Tumor Necrosis Factor; Rifampin; Sildenafil Citrate; Sulfides; Sulfones; Thionucleotides | 1999 |
Pulmonary eosinophilia associated with montelukast.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Fever; Humans; Leukotriene Antagonists; Male; Pulmonary Eosinophilia; Quinolines; Respiratory Sounds; Sulfides | 1999 |
[The value of leukotriene receptor antagonists in the therapy of bronchial asthma one year following the introduction of Montelukast. Symposium at Munich, 6 March 1999].
Topics: Acetates; Asthma; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 1999 |
Failure of montelukast to prevent anaphylaxis to diclofenac.
Topics: Acetates; Adult; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclopropanes; Diclofenac; Drug Hypersensitivity; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides; Treatment Failure | 1999 |
[Asthma therapy in children and adults. Comment on the contribution by Wettengel R., et al. Recommendations of the German Respiratory League in the German Society of Pneumology].
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Humans; Leukotriene Antagonists; Leukotrienes; Quinolines; Sulfides | 1999 |
Leukotriene receptor antagonists versus inhaled steroids in asthma.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Beclomethasone; Chronic Disease; Cyclopropanes; Double-Blind Method; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Middle Aged; Quinolines; Randomized Controlled Trials as Topic; Reproducibility of Results; Sulfides; Treatment Outcome | 1999 |
Leukotriene modifiers--a new treatment option for asthma.
Topics: Acetates; Anti-Asthmatic Agents; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome | 1999 |
Treatment of eosinophilic gastroenteritis with montelukast.
Topics: Acetates; Adolescent; Cyclopropanes; Eosinophilia; Female; Gastroenteritis; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 1999 |
Taking a look at new advances in asthma therapy.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Indoles; Leukotriene Antagonists; Nebulizers and Vaporizers; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 1999 |
Leukotriene modifiers and Churg-Strauss syndrome: adverse effect or response to corticosteroid withdrawal?
Topics: Acetates; Adrenal Cortex Hormones; Asthma; Chromones; Churg-Strauss Syndrome; Cyclopropanes; Eosinophils; Female; Humans; Indoles; Leukotriene Antagonists; Leukotrienes; Middle Aged; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 1999 |
Montelukast, a leukotriene receptor antagonist, inhibits the late airway response to antigen, airway eosinophilia, and IL-5-expressing cells in Brown Norway rats.
Topics: Acetates; Airway Resistance; Animals; Antigens; Area Under Curve; Bronchoalveolar Lavage Fluid; Cyclopropanes; Eosinophils; Gene Expression; Immunohistochemistry; Immunophenotyping; In Situ Hybridization; Interleukin-5; Leukotriene Antagonists; Lung; Myelin Basic Protein; Ovalbumin; Quinolines; Rats; Rats, Inbred BN; RNA, Messenger; Sulfides | 1999 |
Leukotriene receptor antagonist drugs for asthma.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Chronic Disease; Cyclopropanes; Humans; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 1999 |
Inhaled corticosteroids or antileukotrienes for asthma?
Topics: Acetates; Administration, Inhalation; Anti-Asthmatic Agents; Asthma; Beclomethasone; Cyclopropanes; Glucocorticoids; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 1999 |
[Successful and effective: Montelukast in clinical practice].
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides; Treatment Outcome | 1999 |
Montelukast. No current use for asthma.
Topics: Acetates; Administration, Inhalation; Anti-Asthmatic Agents; Asthma; Chronic Disease; Cyclopropanes; Drug Costs; Humans; Quinolines; Steroids; Sulfides | 2000 |
Churg-Strauss syndrome in patients receiving montelukast as treatment for asthma.
Topics: Acetates; Adrenal Cortex Hormones; Adult; Anti-Asthmatic Agents; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Diagnosis, Differential; Drug Therapy, Combination; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Risk Factors; Sulfides | 2000 |
Leukotriene receptor antagonists: useful in acute asthma?
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2000 |
Successful treatment of delayed pressure urticaria with montelukast.
Topics: Acetates; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Middle Aged; Pressure; Quinolines; Sulfides; Urticaria | 2000 |
Successful outcome of montelukast overdosage in an asthmatic child.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Child, Preschool; Cyclopropanes; Drug Overdose; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides; Treatment Outcome | 2000 |
Drugs for asthma.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adult; Albuterol; Asthma; Bronchial Spasm; Child; Cromolyn Sodium; Cyclopropanes; Exercise; Female; Growth Disorders; Humans; Hydroxyurea; Indoles; Ipratropium; Lactation; Leukotriene Antagonists; Nebulizers and Vaporizers; Nedocromil; Phenylcarbamates; Pregnancy; Pregnancy Complications; Quinolines; Salmeterol Xinafoate; Sulfides; Sulfonamides; Theophylline; Tosyl Compounds | 2000 |
Montelukast and Churg-Strauss syndrome.
Topics: Acetates; Adult; Churg-Strauss Syndrome; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2000 |
The use of newer asthma and allergy medications during pregnancy. The American College of Obstetricians and Gynecologists (ACOG) and The American College of Allergy, Asthma and Immunology (ACAAI).
Topics: Abnormalities, Drug-Induced; Acetates; Administration, Inhalation; Administration, Intranasal; Administration, Oral; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Albuterol; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Budesonide; Chlorpheniramine; Cyclopropanes; Ephedrine; Female; Histamine H1 Antagonists; Humans; Hydroxyurea; Hypersensitivity; Indoles; Ipratropium; Leukotriene Antagonists; Metaproterenol; Nasal Decongestants; Nebulizers and Vaporizers; Nedocromil; Phenylcarbamates; Pregnancy; Pregnancy Complications; Quinolines; Salmeterol Xinafoate; Sulfides; Sulfonamides; Terbutaline; Tosyl Compounds; Tripelennamine | 2000 |
Marked peripheral edema associated with montelukast and prednisone.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Cyclopropanes; Drug Interactions; Edema; Humans; Male; Prednisone; Quinolines; Sulfides | 2000 |
Recurrent panniculitis in a man with asthma receiving treatment with leukotriene-modifying agents.
Topics: Acetates; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Cyclopropanes; Diagnosis, Differential; Erythema Induratum; Humans; Hydroxyurea; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Middle Aged; Panniculitis, Nodular Nonsuppurative; Quinolines; Sulfides | 2000 |
A severe systemic inflammatory reaction following therapy with montelukast (Singulair).
Topics: Acetates; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Cyclopropanes; Dose-Response Relationship, Drug; Female; Glomerulonephritis; Humans; Hypereosinophilic Syndrome; Methylprednisolone; Middle Aged; Prednisolone; Quinolines; Sulfides | 2000 |
Montelukast added to inhaled beclomethasone in treatment of asthma.
Topics: Acetates; Administration, Inhalation; Anti-Asthmatic Agents; Asthma; Beclomethasone; Cyclopropanes; Drug Therapy, Combination; Humans; Quinolines; Sulfides | 2000 |
[Leukotriene antagonists against bronchial asthma. Not a replacement for steroids].
Topics: Acetates; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Drug Therapy, Combination; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 1999 |
Singulair slam.
Topics: Acetates; Anti-Asthmatic Agents; Canada; Cyclopropanes; Humans; Leukotriene Antagonists; Practice Guidelines as Topic; Quinolines; Sulfides | 2000 |
Conflicting message in the title.
Topics: Acetates; Anti-Asthmatic Agents; Canada; Cyclopropanes; Humans; Leukotriene Antagonists; Practice Guidelines as Topic; Quinolines; Sulfides | 2000 |
Role of leukotriene receptor antagonists in pediatric asthma.
Topics: Acetates; Administration, Oral; Asthma; Asthma, Exercise-Induced; Child; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Respiratory Function Tests; Severity of Illness Index; Sulfides | 2000 |
Churg-Strauss syndrome associated with montelukast therapy.
Topics: Acetates; Aged; Anti-Asthmatic Agents; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Quinolines; Radiography; Sulfides; Vital Capacity | 2000 |
Improvement of cold urticaria by treatment with the leukotriene receptor antagonist montelukast.
Topics: Acetates; Adult; Cold Temperature; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Quinolines; Sulfides; Urticaria | 2000 |
Oral montelukast versus inhaled salmeterol to prevent exercise-induced bonchonconstriction.
Topics: Acetates; Albuterol; Anti-Asthmatic Agents; Asthma, Exercise-Induced; Bronchodilator Agents; Cyclopropanes; Ethics, Medical; Humans; Quinolines; Salmeterol Xinafoate; Sulfides | 2000 |
Oral montelukast versus inhaled salmeterol to prevent exercise-induced bronchoconstriction.
Topics: Acetates; Aged; Albuterol; Anti-Asthmatic Agents; Asthma, Exercise-Induced; Bronchodilator Agents; Chemical and Drug Induced Liver Injury; Cyclopropanes; Female; Humans; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Salmeterol Xinafoate; Sulfides; Sulfonamides; Tosyl Compounds | 2000 |
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 30-2000. A 25-year-old man with asthma, cardiac failure, diarrhea, and weakness of the right hand.
Topics: Acetates; Adult; Androstadienes; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Diagnosis, Differential; Diarrhea; Fluticasone; Glucocorticoids; Heart Failure; Humans; Leukotriene Antagonists; Lung; Male; Muscle Hypotonia; Prednisone; Quinolines; Radiography; Sulfides | 2000 |
Inhaled porcine pancreatic elastase causes bronchoconstriction via a bradykinin-mediated mechanism.
Topics: Acetates; Administration, Inhalation; Aerosols; Animals; Bradykinin; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Cyclooxygenase Inhibitors; Cyclopropanes; Diphenhydramine; Histamine Antagonists; Humans; Indomethacin; Leukocyte Elastase; Oligopeptides; Pancreatic Elastase; Quinolines; Sheep; Sulfides; Swine; Tissue Kallikreins | 2000 |
Intravenous montelukast in acute asthma: expensive aminophylline?
Topics: Acetates; Acute Disease; Aminophylline; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Forced Expiratory Volume; Humans; Injections, Intravenous; Leukotriene Antagonists; Quinolines; Sulfides | 2000 |
Follow-up in Montelukast treatment.
Topics: Acetates; Anti-Asthmatic Agents; Biopsy; Churg-Strauss Syndrome; Cyclopropanes; Diagnosis, Differential; Follow-Up Studies; Humans; Lung; Quinolines; Sulfides; Treatment Outcome | 2000 |
Churg-Strauss syndrome: is there an association with leukotriene modifiers?
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Humans; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 2000 |
Montelukast in childhood asthma.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2000 |
A new concept for treatment of sinonasal polyposis.
Topics: Acetates; Adrenal Cortex Hormones; Cyclopropanes; Drug Therapy, Combination; Humans; Leukotriene Antagonists; Nasal Polyps; Paranasal Sinus Diseases; Quinolines; Recurrence; Sulfides | 2000 |
Successful treatment of chronic urticaria.
Topics: Acetates; Adult; Chronic Disease; Cyclopropanes; Drug Therapy, Combination; Female; Humans; Leukotriene Antagonists; Prednisone; Quinolines; Sulfides; Urticaria | 2000 |
[Leukotriene antagonism. Inhibiting inflammation plus bronchodilatation].
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2000 |
[Churg-Strauss syndrome associated with montelukast].
Topics: Acetates; Anti-Asthmatic Agents; Churg-Strauss Syndrome; Cyclopropanes; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Status Asthmaticus; Sulfides; Time Factors | 2000 |
Montelukast is only partially effective in inhibiting aspirin responses in aspirin-sensitive asthmatics.
Topics: Acetates; Adult; Aged; Aspirin; Asthma; Bronchial Spasm; Cyclopropanes; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Quinolines; Sulfides | 2000 |
Mediator involvement in antigen-induced bronchospasm and microvascular leakage in the airways of ovalbumin sensitized Brown Norway rats.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Bronchi; Bronchial Spasm; Capillary Permeability; Cyclopropanes; Histamine; Histamine H1 Antagonists; Leukotriene D4; Male; Methysergide; Ovalbumin; Pyrilamine; Quinolines; Rats; Rats, Inbred BN; Respiratory Hypersensitivity; Serotonin; Serotonin Antagonists; Sulfides; Trachea | 2001 |
Non-parametric estimates of overlap.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Beclomethasone; Computer Simulation; Cyclopropanes; Data Interpretation, Statistical; Female; Hip; Humans; Models, Biological; Osteoporosis, Postmenopausal; Quinolines; Statistics, Nonparametric; Sulfides | 2001 |
Montelukast and Churg-Strauss syndrome.
Topics: Acetates; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2001 |
Intravenous montelukast.
Topics: Acetates; Administration, Oral; Anti-Asthmatic Agents; Cyclopropanes; Forced Expiratory Volume; Humans; Injections, Intravenous; Quinolines; Sulfides | 2000 |
Use of montelukast in the treatment of early childhood wheezing from clinical experience with three cases.
Topics: Acetates; Acute Disease; Age Factors; Bronchiolitis, Viral; Cyclopropanes; Female; Humans; Infant; Leukotriene Antagonists; Leukotrienes; Male; Quinolines; Respiratory Sounds; Sulfides; Treatment Outcome | 2000 |
Changes in asthma drug therapy costs for patients receiving chronic montelukast therapy in the U.K.
Topics: Acetates; Administration, Topical; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Cyclopropanes; Drug Administration Schedule; Drug Costs; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Male; Middle Aged; Quinolines; Retrospective Studies; Salmeterol Xinafoate; Sulfides; United Kingdom | 2001 |
[Anti-inflammatory asthma therapy. Effectiveness depends on compliance].
Topics: Acetates; Administration, Oral; Adult; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Child; Cyclopropanes; Drug Therapy, Combination; Humans; Nebulizers and Vaporizers; Patient Compliance; Quinolines; Steroids; Sulfides | 2001 |
Montelukast and Churg-Strauss syndrome.
Topics: Acetates; Administration, Inhalation; Androstadienes; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Dose-Response Relationship, Drug; Eosinophilia; Fluticasone; Humans; Nebulizers and Vaporizers; Prednisolone; Quinolines; Sulfides | 2001 |
Montelukast and Churg-Strauss syndrome.
Topics: Acetates; Administration, Inhalation; Aged; Anti-Asthmatic Agents; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2001 |
Montelukast sodium in cystic fibrosis.
Topics: Acetates; Adolescent; Adult; Asthma; Cyclopropanes; Cystic Fibrosis; Exercise Tolerance; Female; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides; Treatment Outcome | 2001 |
Case 30-2000: Churg-Strauss syndrome.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Glucocorticoids; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2001 |
[Antileukotrienes in the prevention of postoperative recurrence of nasal polyposis in ASA syndrome].
Topics: Acetates; Adult; Aged; Aspirin; Asthma; Cyclopropanes; Drug Hypersensitivity; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Nasal Polyps; Neoplasm Recurrence, Local; Quinolines; Sulfides; Syndrome | 2000 |
Severe asthma attack in a patient with premenstrual asthma: hot pepper is the possible trigger.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Menstrual Cycle; Quinolines; Sulfides; Vegetables | 2001 |
Correlation of airway obstruction and patient-reported endpoints in clinical studies.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Asthmatic Agents; Asthma; Clinical Trials as Topic; Cyclopropanes; Cysteine; Endpoint Determination; Female; Follow-Up Studies; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Leukotrienes; Male; Middle Aged; Peak Expiratory Flow Rate; Pulmonary Ventilation; Quinolines; Sulfides; Treatment Outcome | 2001 |
Churg-Strauss syndrome with montelukast.
Topics: Acetates; Anti-Asthmatic Agents; Churg-Strauss Syndrome; Cyclopropanes; Humans; Quinolines; Sulfides | 2001 |
Expedient liquid chromatographic method with fluorescence detection for montelukast sodium in micro-samples of plasma.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Chromatography, High Pressure Liquid; Cyclopropanes; Fluorescence; Humans; Light; Quality Control; Quinolines; Reference Standards; Sulfides | 2001 |
Leukotriene receptor antagonists in chronic urticaria.
Topics: Acetates; Adult; Aged; Chronic Disease; Cyclopropanes; Female; Follow-Up Studies; Humans; Indoles; Leukotriene Antagonists; Leukotrienes; Male; Middle Aged; Phenylcarbamates; Quinolines; Remission Induction; Severity of Illness Index; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome; Urticaria | 2001 |
Churg-Strauss syndrome associated with montelukast.
Topics: Acetates; Anti-Asthmatic Agents; Churg-Strauss Syndrome; Cyclopropanes; Follow-Up Studies; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Sulfides | 2001 |
Cysteinyl-leukotriene D(4) receptors in smooth muscle cells.
Topics: Acetates; Cyclopropanes; Dose-Response Relationship, Drug; Humans; Leukotriene Antagonists; Leukotriene D4; Membrane Proteins; Muscle, Smooth; Quinolines; Receptors, Leukotriene; Sulfides; Urinary Bladder | 2001 |
Treatment of interstitial cystitis with montelukast, a leukotriene D(4) receptor antagonist.
Topics: Acetates; Cyclopropanes; Cystitis, Interstitial; Female; Humans; Leukotriene Antagonists; Pain; Pilot Projects; Quinolines; Sulfides; Urination Disorders | 2001 |
What is "more effective asthma control"?
Topics: Acetates; Albuterol; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Chronic Disease; Cyclopropanes; Humans; Peak Expiratory Flow Rate; Quinolines; Salmeterol Xinafoate; Sulfides | 2001 |
[Chewable leukotriene antagonist. New therapy option for asthmatic patients of preschool age].
Topics: Acetates; Administration, Oral; Asthma; Child, Preschool; Clinical Trials as Topic; Cyclopropanes; Dosage Forms; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2001 |
Does leukotriene modulation of eosinophil function explain the therapeutic effectiveness of receptor antagonists in some patients with asthma?
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Endothelium, Vascular; Eosinophils; Humans; Leukotriene Antagonists; Leukotrienes; Quinolines; Sulfides; Treatment Outcome | 2001 |
Effect of a specific cysteinyl leukotriene-receptor 1-antagonist (montelukast) on the transmigration of eosinophils across human umbilical vein endothelial cells.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Cell Movement; Cell Survival; Chemotaxis, Leukocyte; Cyclopropanes; Endothelium, Vascular; Eosinophils; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-13; Leukotriene Antagonists; Male; Membrane Proteins; Platelet Activating Factor; Quinolines; Receptors, Leukotriene; RNA, Messenger; Sensitivity and Specificity; Sulfides; Umbilical Veins | 2001 |
Safety of antileukotriene agents in asthma management.
Topics: Acetates; Asthma; Churg-Strauss Syndrome; Clinical Trials as Topic; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 2001 |
Comparison of montelukast versus budesonide in the treatment of exercise-induced bronchoconstriction.
Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Asthma, Exercise-Induced; Bronchoconstriction; Bronchodilator Agents; Budesonide; Child; Cyclopropanes; Female; Forced Expiratory Volume; Humans; Male; Quinolines; Spirometry; Sulfides | 2001 |
Leukotriene antagonists and symptom control in chronic persistent asthma.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Chronic Disease; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2001 |
[Pharma-clinics. Medication of the month. Montelukast (Singulair)].
Topics: Acetates; Administration, Oral; Adolescent; Adrenal Cortex Hormones; Adult; Asthma; Child; Cyclopropanes; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2001 |
Use of montelukast as steroid-sparing agent for recurrent eosinophilic gastroenteritis.
Topics: Acetates; Adult; Cyclopropanes; Eosinophilia; Gastroenteritis; Glucocorticoids; Humans; Leukotriene Antagonists; Male; Prednisone; Quinolines; Recurrence; Sulfides | 2001 |
Treatment-resistant atopic dermatitis.
Topics: Acetates; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antipruritics; Cyclopropanes; Dermatitis, Atopic; Diabetes Complications; Female; Humans; Hydroxyzine; Leukotriene Antagonists; Prednisone; Quinolines; Sulfides; Treatment Failure | 2001 |
Antileukotriene therapy for allergic fungal sinusitis.
Topics: Acetates; Adult; Cyclopropanes; Female; Humans; Hypersensitivity; Leukotriene Antagonists; Quinolines; Rhinitis; Sinusitis; Sulfides | 2001 |
Effects of antileukotriene among asthmatic patients.
Topics: Acetates; Administration, Oral; Adult; Aged; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Leukotriene Antagonists; Middle Aged; Prospective Studies; Quinolines; Spirometry; Sulfides; Treatment Outcome | 2001 |
The cysteinyl leukotriene D4 receptor antagonist montelukast for the treatment of interstitial cystitis.
Topics: Acetates; Aged; Cyclopropanes; Cystitis, Interstitial; Humans; Leukotriene Antagonists; Male; Mastocytosis; Middle Aged; Pilot Projects; Prospective Studies; Quinolines; Sulfides; Urinary Bladder Diseases | 2001 |
A comparison of asthma-related expenditures for patients started on montelukast versus fluticasone propionate as monotherapy.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Androstadienes; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cohort Studies; Cyclopropanes; Female; Fluticasone; Health Care Costs; Humans; Insurance Claim Review; Male; Middle Aged; Patient Compliance; Quinolines; Respiratory Function Tests; Retrospective Studies; Sulfides; Treatment Outcome | 2001 |
An open audit of montelukast, a leukotriene receptor antagonist, in nasal polyposis associated with asthma.
Topics: Acetates; Adult; Aged; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bleeding Time; Cyclopropanes; Female; Humans; Inspiratory Capacity; Leukotriene Antagonists; Male; Middle Aged; Nasal Polyps; Nitric Oxide; Peak Expiratory Flow Rate; Quinolines; Sensitivity and Specificity; Skin Tests; Sulfides | 2001 |
[Treatment of ASS-Associated Polyposis (ASSAP) with a cysteinyl leukotriene receptor antagonist - a prospective drug study on its antiinflammatory effects].
Topics: Acetates; Adult; Anti-Asthmatic Agents; Aspirin; Asthma; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Nasal Polyps; Quinolines; Recurrence; Sulfides | 2001 |
Acute effects of the cys-leukotriene-1 receptor antagonist, montelukast, on experimental colitis in rats.
Topics: Acetates; Animals; Colitis; Cyclooxygenase 2; Cyclopropanes; Isoenzymes; Leukotriene Antagonists; Leukotriene B4; Male; Membrane Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Quinolines; Rats; Rats, Wistar; Receptors, Leukotriene; Severity of Illness Index; Sulfides | 2001 |
Montelukast for persistent asthma.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Patient Selection; Quinolines; Randomized Controlled Trials as Topic; Reproducibility of Results; Sulfides | 2001 |
Montelukast for persistent asthma.
Topics: Acetates; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Polypharmacy; Quinolines; Reproducibility of Results; Sulfides | 2001 |
Montelukast for persistent asthma.
Topics: Acetates; Anti-Asthmatic Agents; Aspirin; Asthma; Cyclopropanes; Humans; Leukotriene E4; Prednisone; Quinolines; Sulfides | 2001 |
[Pediatric exercise-induced asthma. Still, sports are permitted].
Topics: Acetates; Adolescent; Asthma, Exercise-Induced; Child; Cyclopropanes; Humans; Physical Fitness; Quinolines; Sports; Sulfides | 2001 |
Effects of leukotriene receptor antagonist therapy in patients with chronic rhinosinusitis in a real life rhinology clinic setting.
Topics: Acetates; Chronic Disease; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Rhinitis; Sinusitis; Spirometry; Sulfides | 2001 |
Interferon-gamma modulates cysteinyl leukotriene receptor-1 expression and function in human airway myocytes.
Topics: Acetates; Asthma; Bradykinin; Cells, Cultured; Constriction, Pathologic; Cyclopropanes; Cytoskeleton; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Interferon-gamma; Leukotriene Antagonists; Membrane Proteins; Muscle, Smooth; Pliability; Quinolines; Receptors, Leukotriene; Respiratory Muscles; Reverse Transcriptase Polymerase Chain Reaction; Sulfides; Up-Regulation | 2001 |
Pretreatment with montelukast blocks NSAID-induced urticaria and angioedema.
Topics: Acetates; Adolescent; Adult; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Sulfides; Urticaria | 2001 |
More about Churg-Strauss syndrome and montelukast treatment.
Topics: Acetates; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Duodenum; Female; Humans; Middle Aged; Pyloric Antrum; Quinolines; Sulfides | 2001 |
Adherence to oral montelukast and inhaled fluticasone in children with persistent asthma.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Androstadienes; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Fluticasone; Humans; Infant; Patient Compliance; Quinolines; Retrospective Studies; Sulfides | 2001 |
[Leukotrienes. Interlopers on trips to the park].
Topics: Acetates; Asthma; Cyclopropanes; Humans; Leukotriene Antagonists; Leukotrienes; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides | 2001 |
Montelukast and improvement of eczema: observations from a prescription event monitoring study in England.
Topics: Acetates; Adult; Aged; Child; Cohort Studies; Cyclopropanes; Drug Evaluation; Drug Monitoring; Eczema; England; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Sulfides; Surveys and Questionnaires; Treatment Outcome; Urticaria | 2001 |
A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model.
Topics: Acetates; Acute Disease; Allergens; Analysis of Variance; Animals; Asthma; Bronchoalveolar Lavage Fluid; Chronic Disease; Cyclopropanes; Disease Models, Animal; Drug Evaluation, Preclinical; Eosinophils; Fibrosis; Glycoproteins; Goblet Cells; Hyperplasia; Inflammation; Leukotriene Antagonists; Leukotrienes; Lysophospholipase; Macrophages, Alveolar; Mice; Ovalbumin; Quinolines; Respiratory Mechanics; Sulfides | 2002 |
[Churg-Strauss Syndrome associted with administration of Montelukast in an asthmatic patient withour underlying maintenance corticosteroid treatment].
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Female; Humans; Quinolines; Sulfides | 2002 |
Montelukast and Churg-Strauss syndrome.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Sulfides | 2002 |
Pharmacoeconomic studies of asthma controller drugs: marketing gimmick or icing on the cake?
Topics: Acetates; Administration, Inhalation; Administration, Oral; Androstadienes; Anti-Inflammatory Agents; Asthma; Cohort Studies; Cyclopropanes; Economics, Pharmaceutical; Fluticasone; Humans; Indoles; Leukotriene Antagonists; Managed Care Programs; Marketing of Health Services; Phenylcarbamates; Quinolines; Randomized Controlled Trials as Topic; Sulfides; Sulfonamides; Tosyl Compounds | 2002 |
Economic impact of asthma therapy with fluticasone propionate, montelukast, or zafirlukast in a managed care population.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Androstadienes; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Child; Cohort Studies; Cyclopropanes; Female; Fluticasone; Humans; Indoles; Male; Managed Care Programs; Middle Aged; Phenylcarbamates; Quinolines; Retrospective Studies; Sulfides; Sulfonamides; Tosyl Compounds; United States | 2002 |
Asthma biomarkers and drug trials.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Clinical Trials as Topic; Cyclopropanes; Humans; Inflammation Mediators; Leukotriene Antagonists; Quinolines; Sulfides; Treatment Outcome | 2002 |
Inhaled corticosteroids plus salmeterol or montelukast: effects on resource utilization and costs.
Topics: Acetates; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Adult; Albuterol; Asthma; Bronchodilator Agents; Child; Cyclopropanes; Drug Therapy, Combination; Female; Health Care Costs; Health Maintenance Organizations; Humans; Male; Quinolines; Salmeterol Xinafoate; Sulfides | 2002 |
[Interview with Dr. W. Wiebicke, Bremen. To treat early with anti-inflammatory drugs!].
Topics: Acetates; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Age Factors; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Drug Therapy, Combination; Humans; Leukotriene Antagonists; Lung; Patient Compliance; Phosphodiesterase Inhibitors; Quinolines; Radionuclide Imaging; Respiratory Therapy; Sulfides; Time Factors | 2002 |
High-dose montelukast exposures in a 3-year-old and a 5-year-old child.
Topics: Accidents; Acetates; Anti-Asthmatic Agents; Asthma; Child, Preschool; Cyclopropanes; Dose-Response Relationship, Drug; Emergency Medical Services; Humans; Male; Quinolines; Sulfides | 2002 |
Initial therapy in clinical asthma studies often does not equal therapy for mild, persistent asthma.
Topics: Acetates; Adrenergic beta-Agonists; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Drug Therapy, Combination; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2002 |
Bronchodilator reversibility to albuterol predicts bronchodilator response to salmeterol.
Topics: Acetates; Administration, Inhalation; Airway Resistance; Albuterol; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Cyclopropanes; Drug Therapy, Combination; Forced Expiratory Volume; Humans; Peak Expiratory Flow Rate; Quinolines; Salmeterol Xinafoate; Sulfides; Treatment Outcome | 2002 |
[Churg-Strauss syndrome after treatment with Singulair (montelukast)].
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2002 |
Cysteinyl leukotrienes induce human eosinophil locomotion and adhesion molecule expression via a CysLT1 receptor-mediated mechanism.
Topics: Acetates; Cell Adhesion Molecules; Cell Movement; Child; Cyclopropanes; Cysteine; Eosinophils; Humans; Leukotrienes; Quinolines; Sulfides | 2002 |
Pharmacological differences among CysLT(1) receptor antagonists with respect to LTC(4) and LTD(4) in human lung parenchyma.
Topics: Acetates; Anti-Asthmatic Agents; Binding, Competitive; Chromones; Cyclopropanes; Humans; Kinetics; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Membrane Proteins; Quinolines; Receptors, Leukotriene; Sulfides | 2002 |
New drug treatment for asthma: clinical versus statistical significance.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Forced Expiratory Volume; Humans; Quinolines; Sulfides; Treatment Outcome | 2002 |
[Exercise-induced asthma. Prevention with long-term effect is preferred].
Topics: Acetates; Adolescent; Albuterol; Asthma, Exercise-Induced; Child; Cyclopropanes; Drug Administration Schedule; Humans; Quinolines; Salmeterol Xinafoate; Sulfides; Treatment Outcome | 2002 |
Effect of montelukast, a once-daily leukotriene receptor antagonist, on peak expiratory flow variability.
Topics: Acetates; Adolescent; Adult; Aged; Anti-Asthmatic Agents; Asthma; Chronic Disease; Cyclopropanes; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Middle Aged; Multicenter Studies as Topic; Peak Expiratory Flow Rate; Quinolines; Randomized Controlled Trials as Topic; Respiratory Function Tests; Retrospective Studies; Sulfides | 2002 |
[Churg-Strauss syndrome in an asthmatic man treated with montelukast: continued controversy].
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides; Time Factors | 2002 |
Salmeterol powder provides significantly better benefit than montelukast in asthmatic patients receiving concomitant inhaled corticosteroid therapy.
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Albuterol; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Cyclopropanes; Drug Therapy, Combination; Humans; Powders; Quinolines; Salmeterol Xinafoate; Sulfides | 2002 |
5-Lipoxygenase polymorphism and in-vivo response to leukotriene receptor antagonists.
Topics: Acetates; Adult; Arachidonate 5-Lipoxygenase; Asthma; Cyclopropanes; Forced Expiratory Volume; Genotype; Humans; Indoles; Leukotriene Antagonists; Phenylcarbamates; Polymorphism, Genetic; Quinolines; Retrospective Studies; Sulfides; Sulfonamides; Tosyl Compounds | 2002 |
The effect of cysteinyl leukotrienes on growth of eosinophil progenitors from peripheral blood and bone marrow of atopic subjects.
Topics: Acetates; Adult; Cell Differentiation; Cells, Cultured; Cyclopropanes; Dose-Response Relationship, Drug; Eosinophils; Hematopoietic Stem Cells; Humans; Hypersensitivity, Immediate; Leukotriene Antagonists; Leukotriene D4; Leukotriene E4; Quinolines; Sulfides | 2002 |
Cutaneous lesions of Churg-Strauss syndrome associated with montelukast therapy.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Drug Eruptions; Humans; Leg Dermatoses; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Sulfides | 2002 |
Treatment of asthmatic patients with a cysteinyl leukotriene receptor-1 antagonist montelukast (Singulair), decreases the eosinophil survival-enhancing activity produced by peripheral blood mononuclear leukocytes in vitro.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Cell Survival; Controlled Clinical Trials as Topic; Cyclopropanes; Cytokines; Double-Blind Method; Eosinophils; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukocytes, Mononuclear; Leukotriene Antagonists; Male; Membrane Proteins; Middle Aged; Quinolines; Receptors, Leukotriene; Staining and Labeling; Statistics as Topic; Sulfides; Time Factors; Treatment Outcome | 2002 |
Irritable bowel syndrome helped by montelukast.
Topics: Acetates; Asthma; Celiac Disease; Colonic Diseases, Functional; Cyclopropanes; Humans; Leukotriene Antagonists; Patient Satisfaction; Quinolines; Sulfides; Treatment Outcome | 2002 |
[When children experience asthma during exercise. Excluding sports is outdated].
Topics: Acetates; Anti-Asthmatic Agents; Asthma, Exercise-Induced; Child; Combined Modality Therapy; Cyclopropanes; Humans; Physical Education and Training; Quinolines; Sulfides | 2002 |
Montelukast prevents antigen-induced mucociliary dysfunction in sheep.
Topics: Acetates; Animals; Antigens, Helminth; Ascaris suum; Cyclopropanes; Leukotriene Antagonists; Mucociliary Clearance; Mucus; Quinolines; Respiratory Hypersensitivity; Sheep; Sulfides; Time Factors; Trachea | 2002 |
[Montelukast].
Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Clinical Trials as Topic; Cyclopropanes; Dose-Response Relationship, Drug; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2002 |
Leukotriene antagonism reduces the generation of endothelin-1 and interferon-gamma and inhibits eosinophilic airway inflammation.
Topics: Acetates; Animals; Bronchoalveolar Lavage Fluid; Cell Count; Cyclopropanes; Endothelin-1; Eosinophils; Interferon-gamma; Interleukin-8; Leukotriene Antagonists; Lung; Male; Quinolines; Rats; Rats, Wistar; Sulfides; Tumor Necrosis Factor-alpha | 2002 |
Lateral membrane LXA4 receptors mediate LXA4's anti-inflammatory actions on intestinal epithelium.
Topics: Acetates; Anti-Inflammatory Agents, Non-Steroidal; Cyclopropanes; Genetic Vectors; Humans; Hydroxyeicosatetraenoic Acids; Interleukin-8; Intestinal Mucosa; Leukotriene Antagonists; Lipoxins; Membrane Proteins; Quinolines; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Leukotriene; Receptors, Lipoxin; Retroviridae; Sulfides; Tissue Distribution; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2003 |
Choice of a medication to treat asthma: is an improvement in symptoms sufficient for deciding?
Topics: Acetates; Asthma; Beclomethasone; Cyclopropanes; Forced Expiratory Volume; Humans; Quinolines; Sulfides | 2002 |
[Pharmacological profile and clinical effects of montelukast sodium (Singulair chewable tablet), an antiasthmatic agent].
Topics: Acetates; Animals; Anti-Asthmatic Agents; Cyclopropanes; Guinea Pigs; Humans; Quinolines; Rats; Saimiri; Sulfides | 2002 |
Involvement of the cysteinyl-leukotrienes in allergen-induced airway eosinophilia and hyperresponsiveness in the mouse.
Topics: Acetates; Allergens; Animals; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chemokine CCL11; Chemokines, CC; Cyclopropanes; Eosinophilia; Interleukin-5; Leukotrienes; Male; Mice; Mice, Inbred BALB C; Quinolines; Sulfides | 2003 |
Lipoxin A4 stimulates a cytosolic Ca2+ increase in human bronchial epithelium.
Topics: Acetates; Alkaloids; Base Sequence; Benzophenanthridines; Bronchi; Calcium; Cell Line, Transformed; Cyclic AMP; Cyclopropanes; Cytosol; DNA Primers; Epithelial Cells; Humans; Hydroxyeicosatetraenoic Acids; Imines; Lipoxins; Pertussis Toxin; Phenanthridines; Quinolines; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin; Reverse Transcriptase Polymerase Chain Reaction; Sulfides | 2003 |
Dispensing error leading to alendronate ingestion.
Topics: Acetates; Alendronate; Asthma; Calcium Channel Blockers; Child; Cyclopropanes; Drug Packaging; Esophagitis; Humans; Leukotriene Antagonists; Male; Medication Errors; Quinolines; Sulfides | 2003 |
Asthma control and patient satisfaction among early pediatric users of montelukast.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Child; Child Welfare; Cyclopropanes; Disease Management; Female; Follow-Up Studies; Humans; Male; Patient Satisfaction; Prospective Studies; Quinolines; Sulfides; Time; Time Factors; Treatment Outcome; United States | 2002 |
Montelukast pharmacokinetics in cystic fibrosis.
Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Case-Control Studies; Chromatography, High Pressure Liquid; Cyclopropanes; Cystic Fibrosis; Drug Administration Schedule; Female; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2003 |
Eosinophilic oesophagitis: a novel treatment using Montelukast.
Topics: Acetates; Adult; Age of Onset; Biopsy; Cyclopropanes; Deglutition Disorders; Eosinophilia; Esophagitis; Esophagoscopy; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Sulfides; Treatment Outcome | 2003 |
[Leukotriene antagonist. All around talent in asthma and allergies].
Topics: Acetates; Asthma; Cyclopropanes; Dermatitis, Atopic; Humans; Leukotriene Antagonists; Quinolines; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sulfides; Treatment Outcome | 2002 |
Montelukast reduces peripheral blood eosinophilia but not tissue eosinophilia or symptoms in a patient with eosinophilic gastroenteritis and esophageal stricture.
Topics: Acetates; Adult; Cyclopropanes; Eosinophilia; Eosinophils; Esophageal Stenosis; Gastroenteritis; Humans; Leukocyte Count; Leukotriene Antagonists; Male; Quinolines; Sulfides; Treatment Outcome | 2003 |
Montelukast: use in pediatric patients with eosinophilic gastrointestinal disease.
Topics: Acetates; Adolescent; Child; Child, Preschool; Cyclopropanes; Eosinophilia; Female; Gastroenteritis; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides; Treatment Outcome | 2003 |
Montelukast for respiratory syncytial virus bronchiolitis: significant effect or provocative findings?
Topics: Acetates; Bronchiolitis, Viral; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Respiratory Syncytial Virus Infections; Sulfides | 2003 |
Impact of montelukast on symptoms in mild-to-moderate persistent asthma and exercise-induced asthma: results of the ASTHMA survey. Adding Singulair Treatment to Handle symptoms in Mild to moderate Asthmatics.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Belgium; Child; Cyclopropanes; Data Collection; Exercise; Female; Humans; Male; Patient Satisfaction; Physicians, Family; Quinolines; Sulfides | 2002 |
Broadening the therapeutic options in acute asthma.
Topics: Acetates; Acute Disease; Asthma; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2003 |
[Montelukast induced cytolytic acute hepatitis].
Topics: Acetates; Acute Disease; Adult; Anti-Asthmatic Agents; Chemical and Drug Induced Liver Injury; Cyclopropanes; Female; Follow-Up Studies; Humans; Leukotriene Antagonists; Quinolines; Sulfides; Time Factors | 2003 |
[Acute hepatitis due to montelukast].
Topics: Acetates; Acute Disease; Anti-Asthmatic Agents; Chemical and Drug Induced Liver Injury; Cyclopropanes; Female; Humans; Middle Aged; Quinolines; Sulfides | 2003 |
Simultaneous determination of montelukast and loratadine by HPLC and derivative spectrophotometric methods.
Topics: Acetates; Anti-Asthmatic Agents; Calibration; Chromatography, High Pressure Liquid; Cyclopropanes; Histamine H1 Antagonists, Non-Sedating; Loratadine; Pharmaceutical Preparations; Quinolines; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Sulfides | 2003 |
Anti-inflammatory effects of high-dose montelukast in an animal model of acute asthma.
Topics: Acetates; Administration, Inhalation; Animals; Asthma; Bronchoalveolar Lavage Fluid; Chemokines, CC; Cyclopropanes; Eosinophils; Humans; Immunoglobulin E; Interleukins; Leukocyte Count; Leukotriene Antagonists; Mice; Mice, Inbred BALB C; Models, Animal; Ovalbumin; Quinolines; RNA, Messenger; Sulfides; Th2 Cells; Vascular Cell Adhesion Molecule-1 | 2003 |
Anti-leukotriene drugs in the prevention and treatment of hepatorenal syndrome.
Topics: Acetates; Arachidonic Acid; Cyclopropanes; Hepatorenal Syndrome; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Liver; Phenylcarbamates; Protein Structure, Tertiary; Quinolines; Sulfides; Sulfonamides; Thromboxanes; Tosyl Compounds | 2003 |
Effect of pharmacist counseling in patients hospitalized with acute exacerbation of asthma.
Topics: Acetates; Acute Disease; Administration, Inhalation; Adrenal Cortex Hormones; Adult; Albuterol; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Counseling; Cyclopropanes; Female; Hospitals, Teaching; Humans; Inpatients; Male; Middle Aged; Patient Compliance; Patient Education as Topic; Patient Satisfaction; Pharmacists; Quinolines; Salmeterol Xinafoate; Sulfides; United States | 2003 |
Montelukast (singulair) for allergic rhinitis.
Topics: Acetates; Administration, Intranasal; Administration, Oral; Adrenal Cortex Hormones; Cyclopropanes; Double-Blind Method; Humans; Inflammation Mediators; Intestinal Absorption; Leukotriene Antagonists; Quinolines; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Seasonal; Sulfides | 2003 |
A semi-automated 96-well protein precipitation method for the determination of montelukast in human plasma using high performance liquid chromatography/fluorescence detection.
Topics: Acetates; Chemical Precipitation; Chromatography, High Pressure Liquid; Cyclopropanes; Humans; Proteins; Quinolines; Spectrometry, Fluorescence; Sulfides | 2003 |
Acute hepatitis associated with montelukast.
Topics: Acetates; Acute Disease; Aged; Anti-Asthmatic Agents; Asthma; Chemical and Drug Induced Liver Injury; Cyclopropanes; Humans; Male; Quinolines; Sulfides | 2003 |
Montelukast does not protect against hyperoxia-induced inhibition of alveolarization in newborn rats.
Topics: Acetates; Animals; Animals, Newborn; Cyclopropanes; Hyperoxia; Leukotriene Antagonists; Pulmonary Alveoli; Quinolines; Rats; Rats, Wistar; Sulfides | 2003 |
Wheeze monitoring in children for assessment of nocturnal asthma and response to therapy.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Bronchial Provocation Tests; Child; Cyclopropanes; Female; Humans; Male; Monitoring, Physiologic; Pilot Projects; Prospective Studies; Quinolines; Respiratory Sounds; Sleep; Statistics, Nonparametric; Sulfides | 2003 |
Protective effect of leukotriene receptor antagonist montelukast on smoking-induced lung injury in Wistar rats.
Topics: Acetates; Animals; Cyclopropanes; Female; Leukotriene Antagonists; Lung Diseases; Macrophages, Alveolar; Mast Cells; Protective Agents; Quinolines; Rats; Rats, Wistar; Smoking; Sulfides | 2003 |
Asthma variability.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Beclomethasone; Clinical Trials as Topic; Cyclopropanes; Humans; Quinolines; Sulfides; Treatment Outcome | 2003 |
Role of leukotrienes in the regulation of human granulocyte behaviour: dissociation between agonist-induced activation and retardation of apoptosis.
Topics: Acetates; Adjuvants, Immunologic; Apoptosis; Benzopyrans; Calcium; Carboxylic Acids; Cell Survival; Cells, Cultured; Cyclopropanes; Eosinophils; Humans; Leukotriene Antagonists; Leukotriene B4; Leukotriene D4; Neutrophils; Quinolines; Sulfides | 2003 |
Do leukotriene receptor antagonists have a place in pharmacotherapy of allergic rhinitis?
Topics: Acetates; Administration, Intranasal; Administration, Oral; Androstadienes; Anti-Allergic Agents; Cyclopropanes; Fluticasone; Humans; Leukotriene Antagonists; Loratadine; Quinolines; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Seasonal; Sulfides | 2003 |
Childhood pemphigus associated with montelukast administration.
Topics: Acetates; Anti-Asthmatic Agents; Child; Cyclopropanes; Drug Eruptions; Female; Humans; Leukotriene Antagonists; Pemphigus; Quinolines; Sulfides | 2003 |
The early allergic response in small airways of human precision-cut lung slices.
Topics: Acetates; Anti-Allergic Agents; Anti-Asthmatic Agents; Bridged Bicyclo Compounds, Heterocyclic; Bronchi; Bronchial Provocation Tests; Bronchoconstriction; Cilia; Culture Techniques; Cyclopropanes; Fatty Acids, Unsaturated; Humans; Hydrazines; Hypersensitivity; Immunization, Passive; Lung; Quinolines; Reaction Time; Sulfides; Time Factors; Triprolidine | 2003 |
[Leukotriene antagonist added in asthma therapy. Loophole in anti-inflammatory therapy closed].
Topics: Acetates; Adult; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Budesonide; Clinical Trials as Topic; Cyclopropanes; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2003 |
Acute Churg-Strauss syndrome in an asthmatic patient receiving montelukast therapy.
Topics: Acetates; Acute Disease; Anti-Asthmatic Agents; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Humans; Male; Middle Aged; Quinolines; Skin Diseases; Sulfides | 2003 |
The cysteinyl-leukotriene D4 induces cytosolic Ca2+ elevation and contraction of the human detrusor muscle.
Topics: Acetates; Calcium; Cells, Cultured; Cyclopropanes; Cysteine; Cytosol; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Indoles; Leukotriene Antagonists; Leukotriene D4; Leukotrienes; Membrane Proteins; Muscle Contraction; Muscle, Smooth; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Sarcoplasmic Reticulum; Sulfides; Sulfonamides; Tosyl Compounds; Urinary Bladder | 2003 |
Effects of cysteinyl leukotrienes in small human bronchus and antagonist activity of montelukast and its metabolites.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cyclopropanes; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Male; Middle Aged; Quinolines; Reverse Transcriptase Polymerase Chain Reaction; Sulfides | 2003 |
Efficacy of montelukast in the treatment of chronic obstructive pulmonary disease in five horses.
Topics: Acetates; Animals; Cyclopropanes; Female; Horse Diseases; Horses; Leukotriene Antagonists; Male; Pulmonary Disease, Chronic Obstructive; Quinolines; Respiration; Severity of Illness Index; Sulfides; Treatment Outcome | 2003 |
Eosinophilic oesophagitis: treatment using Montelukast.
Topics: Acetates; Cyclopropanes; Eosinophilia; Esophagitis; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2003 |
Effect of montelukast on polymorphonuclear leukocyte functions in asthmatic patients.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Candida albicans; Cyclopropanes; Humans; Leukotriene Antagonists; Middle Aged; Neutrophils; Phagocytosis; Quinolines; Sulfides | 2003 |
[Preventive effects of montelukast on hypoxic pulmonary hypertension in rats].
Topics: Acetates; Animals; Cyclopropanes; Hypertension, Pulmonary; Hypoxia; Leukotriene Antagonists; Leukotriene C4; Male; Membrane Proteins; Quinolines; Random Allocation; Rats; Rats, Wistar; Receptors, Leukotriene; Sulfides | 2003 |
Adherence to montelukast versus inhaled corticosteroids in children with asthma.
Topics: Acetates; Androstadienes; Beclomethasone; Bronchodilator Agents; Child; Cyclopropanes; Female; Fluticasone; Glucocorticoids; Humans; Leukotriene Antagonists; Male; Patient Compliance; Quinolines; Retrospective Studies; Sulfides; Treatment Outcome; Triamcinolone Acetonide | 2003 |
Montelukast-associated Churg-Strauss syndrome.
Topics: Acetates; Aged; Anti-Asthmatic Agents; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2003 |
Outcomes of patients treated with fluticasone propionate or montelukast sodium.
Topics: Acetates; Adolescent; Adult; Androstadienes; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Emergency Service, Hospital; Female; Fluticasone; Hospitalization; Humans; Male; Middle Aged; Multivariate Analysis; Outcome Assessment, Health Care; Quinolines; Retrospective Studies; Sulfides; United States | 2003 |
Churg-Strauss syndrome: clinical presentation, antineutrophil cytoplasmic antibodies, and leukotriene receptor antagonists.
Topics: Acetates; Adolescent; Adult; Aged; Antibodies, Antineutrophil Cytoplasmic; Asthma; Biopsy; Central Nervous System Diseases; Child; Churg-Strauss Syndrome; Cyclopropanes; Electromyography; Eosinophilic Granuloma; Female; Follow-Up Studies; Glucocorticoids; Humans; Immunosuppressive Agents; Indoles; Leukotriene Antagonists; Male; Middle Aged; Minnesota; Peroxidase; Phenylcarbamates; Predictive Value of Tests; Quinolines; Statistics as Topic; Sulfides; Sulfonamides; Survival Analysis; Tosyl Compounds; Treatment Outcome | 2003 |
Distribution of therapeutic response in asthma control.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Beclomethasone; Cyclopropanes; Humans; Quinolines; Statistics as Topic; Sulfides | 2003 |
A leukotriene receptor antagonist modulates iNOS in the lung and in a leukotriene-free cell model.
Topics: Acetates; Allergens; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchoalveolar Lavage Fluid; Cell Line; Cyclopropanes; Cysteine; Cytokines; Dexamethasone; Epithelial Cells; Immunohistochemistry; Leukotriene Antagonists; Leukotrienes; Lung; Male; Models, Animal; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Quinolines; Rats; Rats, Inbred BN; Sulfides | 2003 |
[A study on the heterogeneous apoptosis of lymphocytes, eosinophils, and neutrophils from peripheral blood of asthmatic patients].
Topics: Acetates; Adult; Apoptosis; Asthma; Caspase 3; Caspases; Cyclopropanes; Dexamethasone; Eosinophils; fas Receptor; Female; Humans; Lymphocytes; Male; Neutrophils; Quinolines; Sulfides | 2003 |
Nasal cytokine modulation by montelukast in allergic children: a pilot study.
Topics: Acetates; Adolescent; Child; Cyclopropanes; Drug Evaluation; Female; Humans; Interferon-gamma; Interleukin-13; Interleukin-4; Leukotriene Antagonists; Lymphokines; Male; Nasal Cavity; Pilot Projects; Quinolines; Single-Blind Method; Sulfides; Th1 Cells; Th2 Cells | 2003 |
Effect of montelukast pretreatment on inducible nitric oxide synthase mRNA expression in the lungs of antigen-challenged allergic mice.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Antigens; Asthma; Cyclopropanes; Dexamethasone; Female; Leukotriene Antagonists; Lung; Mice; Mice, Inbred BALB C; Models, Animal; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Quinolines; RNA, Messenger; Skin Tests; Sulfides | 2003 |
Characterization of cysteinyl leukotriene receptors on human saphenous veins: antagonist activity of montelukast and its metabolites.
Topics: Acetates; Adult; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Membrane Proteins; Middle Aged; Muscle, Smooth, Vascular; Quinolines; Receptors, Leukotriene; Reverse Transcriptase Polymerase Chain Reaction; Saphenous Vein; Sulfides; Vasoconstriction | 2004 |
Intravenous montelukast in acute asthma.
Topics: Acetates; Acute Disease; Adult; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Female; Humans; Infusions, Intravenous; Male; Peak Expiratory Flow Rate; Quinolines; Randomized Controlled Trials as Topic; Risk Assessment; Severity of Illness Index; Sulfides; Treatment Outcome | 2004 |
Montelukast and fluticasone propionate.
Topics: Acetates; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Cyclopropanes; Fluticasone; Humans; Leukotriene Antagonists; Peak Expiratory Flow Rate; Quinolines; Sulfides | 2003 |
[An anti-leukotriene combined with inhaled corticosteroids: results of the COMPACT study].
Topics: Acetates; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Asthma; Bronchodilator Agents; Budesonide; Chronic Disease; Cyclopropanes; Drug Therapy, Combination; Humans; Leukotriene Antagonists; Middle Aged; Quinolines; Sulfides | 2003 |
[Adding a prolonged action beta-2-agonist].
Topics: Acetates; Adrenergic beta-Agonists; Albuterol; Asthma; Bronchodilator Agents; Chronic Disease; Cyclopropanes; Delayed-Action Preparations; Drug Therapy, Combination; Humans; Leukotriene Antagonists; Quinolines; Salmeterol Xinafoate; Sulfides | 2003 |
[Adding an anti-leukotriene: results of the IMPACT study].
Topics: Acetates; Adrenergic beta-Agonists; Albuterol; Androstadienes; Asthma; Bronchodilator Agents; Chronic Disease; Cyclopropanes; Delayed-Action Preparations; Drug Therapy, Combination; Ethanolamines; Fluticasone; Formoterol Fumarate; Humans; Leukotriene Antagonists; Quinolines; Salmeterol Xinafoate; Sulfides | 2003 |
Effectiveness of leukotriene receptor antagonists for dysmenorrhea of endometriosis.
Topics: Acetates; Cyclopropanes; Dysmenorrhea; Endometriosis; Female; Humans; Leukotriene Antagonists; Pilot Projects; Quinolines; Sulfides; Treatment Outcome | 2004 |
Inverse agonist activity of selected ligands of the cysteinyl-leukotriene receptor 1.
Topics: Acetates; Animals; Chlorocebus aethiops; COS Cells; Cyclopropanes; GTP-Binding Proteins; Humans; Indoles; Leukotriene Antagonists; Membrane Proteins; Phenylcarbamates; Propionates; Quinolines; Radioligand Assay; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds; Transfection | 2004 |
Intravenous montelukast in acute asthma.
Topics: Acetates; Acute Disease; Anti-Asthmatic Agents; Asthma; Critical Care; Cyclopropanes; Female; Humans; Infusions, Intravenous; Male; Prognosis; Quinolines; Risk Assessment; Severity of Illness Index; Sulfides; Treatment Outcome | 2004 |
Comparison of glucocorticoid and cysteinyl leukotriene receptor antagonist treatments in an experimental model of chronic airway inflammation in guinea-pigs.
Topics: Acetates; Animals; Asthma; Chronic Disease; Cyclopropanes; Dexamethasone; Eosinophils; Glucocorticoids; Guinea Pigs; Leukocyte Count; Leukotriene Antagonists; Lung; Male; Quinolines; Sulfides | 2004 |
Increase in urinary leukotriene LTE4 levels in acute asthma: correlation with airflow limitation.
Topics: Acetates; Acute Disease; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Forced Expiratory Volume; Humans; Infusions, Intravenous; Leukotriene Antagonists; Leukotriene E4; Middle Aged; Quinolines; Sulfides | 2004 |
Montelukast in RSV-bronchiolitis.
Topics: Acetates; Bronchiolitis, Viral; Child, Preschool; Cyclopropanes; Humans; Quinolines; Respiratory Syncytial Virus Infections; Sulfides | 2004 |
Improved refill persistence with fluticasone propionate and salmeterol in a single inhaler compared with other controller therapies.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adult; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Cohort Studies; Cyclopropanes; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluticasone; Health Maintenance Organizations; Humans; Male; Nebulizers and Vaporizers; Patient Compliance; Quinolines; Retrospective Studies; Salmeterol Xinafoate; Sulfides | 2004 |
Leukotriene-receptor inhibition for the treatment of systemic mastocytosis.
Topics: Acetates; Anti-Inflammatory Agents; Cyclopropanes; Drug Therapy, Combination; Humans; Infant; Leukotriene Antagonists; Male; Mastocytosis, Systemic; Prednisone; Quinolines; Sulfides | 2004 |
Long-term montelukast therapy in moderate to severe COPD--a preliminary observation.
Topics: Acetates; Aged; Cyclopropanes; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Long-Term Care; Male; Pulmonary Disease, Chronic Obstructive; Quinolines; Retrospective Studies; Sulfides; Vital Capacity | 2004 |
Combined mediator antagonism for allergic rhinitis.
Topics: Acetates; Cetirizine; Cyclopropanes; Drug Therapy, Combination; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides | 2004 |
Leukotriene receptor antagonists are ineffective for severe atopic dermatitis.
Topics: Acetates; Adolescent; Adult; Aged; Child; Child, Preschool; Cyclopropanes; Dermatitis, Atopic; Female; Humans; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome | 2004 |
[Cardioprotective effect and influence on NOS expression of Montelukast sodium in rats].
Topics: Acetates; Animals; Cardiotonic Agents; Cyclopropanes; Female; Isoproterenol; Leukotriene Antagonists; Male; Myocardial Ischemia; Myocardium; Necrosis; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Quinolines; Rats; Rats, Sprague-Dawley; Sulfides | 2003 |
Exhaled gas analysis and airway inflammation.
Topics: Acetates; Asthma; Breath Tests; Carbon Monoxide; Cyclopropanes; Glucocorticoids; Humans; Leukotriene Antagonists; Nitric Oxide; Quinolines; Respiratory Function Tests; Sulfides | 2004 |
Airway inflammation and asthma treatment modalities.
Topics: Acetates; Asthma; Bronchial Hyperreactivity; Child; Cyclopropanes; Humans; Immune System; Immunotherapy; Inflammation; Leukotriene Antagonists; Quinolines; Sulfides | 2004 |
Leukotriene modifier use and asthma severity: how is a new medication being used by adults with asthma?
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Female; Health Status Indicators; Hospitalization; Humans; Hydroxyurea; Leukotriene Antagonists; Logistic Models; Longitudinal Studies; Male; Middle Aged; Prospective Studies; Quinolines; Sulfides | 2004 |
Exhaled nitric oxide.
Topics: Acetates; Albuterol; Asthma; Breath Tests; Bronchodilator Agents; Budesonide; Cyclopropanes; Exhalation; Humans; Nitric Oxide; Quinolines; Respiratory Function Tests; Salmeterol Xinafoate; Sulfides | 2004 |
Churg-Strauss syndrome associated with the leukotriene antagonist montelukast.
Topics: Acetates; Aged; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Electrophysiology; Female; Humans; Leukotriene Antagonists; Pain; Peripheral Nervous System Diseases; Quinolines; Sulfides | 2004 |
Montelukast-induced hepatitis.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Chemical and Drug Induced Liver Injury; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2004 |
Natural history of primary eosinophilic esophagitis: a follow up of 30 adult patients for up to 11.5 years.
Topics: Acetates; Child; Cyclopropanes; Deglutition Disorders; Diet; Eosinophilia; Esophagitis; Esophagus; Follow-Up Studies; Humans; Leukotriene Antagonists; Quinolines; Steroids; Sulfides; Treatment Outcome | 2004 |
Churg Strauss syndrome during treatment of bronchial asthma with a leucotriene receptor antagonist presenting with polyneuropathy.
Topics: Acetates; Aged; Anti-Asthmatic Agents; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Humans; Leukotriene Antagonists; Male; Muscle, Skeletal; Quinolines; Sulfides; Sural Nerve | 2004 |
Effects of glucocorticoid and cysteinyl leukotriene 1 receptor antagonist on CD(34+) hematopoietic cells in bone marrow of asthmatic mice.
Topics: Acetates; Animals; Antigens, CD34; Asthma; Cell Count; Cyclopropanes; Hematopoietic Stem Cells; Immunohistochemistry; In Situ Hybridization; Interleukin-5; Male; Mice; Mice, Inbred BALB C; Prednisone; Quinolines; Sulfides | 2004 |
Montelukast-induced generalized urticaria.
Topics: Acetates; Adult; Cyclopropanes; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides; Urticaria | 2004 |
[The effects of anti-inflammatory and anti-asthmatic agents on CD34+ hematopoietic cells in bone marrow of asthmatic mice].
Topics: Acetates; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Antigens, CD34; Asthma; Bronchoalveolar Lavage Fluid; Cyclopropanes; Hematopoietic Stem Cells; Interleukin-5 Receptor alpha Subunit; Male; Mice; Mice, Inbred BALB C; Prednisone; Quinolines; Receptors, Interleukin; RNA, Messenger; Sulfides | 2004 |
Montelukast in respiratory syncytial virus postbronchiolitis.
Topics: Acetates; Bronchiolitis, Viral; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Respiratory Syncytial Virus Infections; Sulfides | 2004 |
Effect of montelukast, a cysteinyl receptor antagonist, on myofibroblasts in interstitial lung disease.
Topics: Acetates; Actins; Adult; Cell Proliferation; Cells, Cultured; Cyclopropanes; Female; Fibroblasts; Fibrosis; Humans; Lung Diseases, Interstitial; Male; Middle Aged; Quinolines; RNA, Messenger; Sarcoidosis; Sulfides; Transforming Growth Factor beta | 2004 |
Acquired thrombopathia related to montelukast therapy.
Topics: Acetates; Adult; Asthma; Blood Platelet Disorders; Cyclopropanes; Female; Hemorrhage; Humans; Leukotriene Antagonists; Platelet Function Tests; Quinolines; Sulfides | 2004 |
Evaluating the effectiveness of asthma treatment in real-life practice.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Evidence-Based Medicine; Humans; Pilot Projects; Quinolines; Randomized Controlled Trials as Topic; Sulfides; United Kingdom | 2004 |
Asthma hospitalization risk and costs for patients treated with fluticasone propionate vs montelukast.
Topics: Acetates; Adult; Androstadienes; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Female; Fluticasone; Health Care Costs; Hospitalization; Humans; Male; Quinolines; Retrospective Studies; Sulfides; Treatment Outcome | 2004 |
Reduced eosinophil pro-fibrogenic effect in severe childhood asthma compared to mild disease: an effect of corticosteroids?
Topics: Acetates; Adolescent; Albuterol; Androstadienes; Asthma; Child; Cyclopropanes; Dexamethasone; Eosinophils; Female; Fibroblasts; Fluticasone; Glucocorticoids; Humans; In Vitro Techniques; Male; Quinolines; Salmeterol Xinafoate; Sulfides | 2004 |
Cysteinyl leukotrienes and collagen type I synthesis in asthma.
Topics: Acetates; Adult; Androstadienes; Anti-Inflammatory Agents; Asthma; Collagen Type I; Cyclopropanes; Eosinophils; Female; Fluticasone; Humans; Leukotriene Antagonists; Male; Membrane Proteins; Middle Aged; Peptide Fragments; Pilot Projects; Procollagen; Quinolines; Receptors, Leukotriene; Sputum; Sulfides | 2004 |
Successful combined therapy for refractory chronic urticaria in a 10-year-old boy.
Topics: Acetates; Aminocaproic Acid; Child; Chronic Disease; Cyclopropanes; Drug Therapy, Combination; Humans; Male; Quinolines; Ranitidine; Sulfides; Urticaria | 2004 |
Cost effectiveness of fluticasone propionate plus salmeterol versus fluticasone propionate plus montelukast in the treatment of persistent asthma.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adult; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Chronic Disease; Cost-Benefit Analysis; Cyclopropanes; Drug Therapy, Combination; Female; Fluticasone; Humans; Male; Nebulizers and Vaporizers; Prospective Studies; Quinolines; Randomized Controlled Trials as Topic; Salmeterol Xinafoate; Sulfides | 2004 |
Blockade of leukotriene B4 prevents articular incapacitation in rat zymosan-induced arthritis.
Topics: Acetates; Animals; Arthritis, Experimental; Benzeneacetamides; Cell Movement; Cyclopropanes; Exudates and Transudates; Hindlimb; Hydroxamic Acids; Indoles; Joints; Leukotriene Antagonists; Leukotriene B4; Male; Quinolines; Rats; Rats, Wistar; Sulfides; Zymosan | 2004 |
Montelukast and Churg-Strauss syndrome.
Topics: Acetates; Asthma; Biopsy, Needle; Churg-Strauss Syndrome; Cyclopropanes; Drug Therapy, Combination; Follow-Up Studies; Humans; Immunohistochemistry; Immunosuppressive Agents; Leukotriene Antagonists; Male; Middle Aged; Pulmonary Eosinophilia; Quinolines; Radiography, Thoracic; Risk Assessment; Severity of Illness Index; Sulfides; Switzerland; Treatment Outcome | 2004 |
The benign clinical course following a large pediatric montelukast ingestion.
Topics: Acetates; Anti-Asthmatic Agents; Cyclopropanes; Drug Overdose; Emergency Medical Services; Female; Humans; Infant; Leukotriene Antagonists; Quinolines; Sulfides | 2004 |
Effects of a cysteinyl leukotriene receptor antagonist on eosinophil recruitment in experimental allergic rhinitis.
Topics: Acetates; Animals; Basophils; Bone Marrow; Cell Differentiation; Culture Techniques; Cyclopropanes; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoiesis; Interleukin-3; Interleukin-5; Leukocyte Count; Leukotriene Antagonists; Membrane Proteins; Mice; Mice, Inbred BALB C; Nasal Mucosa; Quinolines; Receptors, Leukotriene; Rhinitis, Allergic, Perennial; Stem Cells; Sulfides | 2004 |
[The effect of montelukast on airway remodeling and the expression of interleukins and transforming growth factor-beta2 mRNA].
Topics: Acetates; Animals; Asthma; Bronchi; Cyclopropanes; Disease Models, Animal; Eosinophils; Female; Interleukins; Leukotriene Antagonists; Mice; Mice, Inbred BALB C; Quinolines; Random Allocation; RNA, Messenger; Sulfides; Transforming Growth Factor beta; Transforming Growth Factor beta2 | 2004 |
Montelukast, a cysteinyl leukotriene receptor-1 antagonist, dose- and time-dependently protects against focal cerebral ischemia in mice.
Topics: Acetates; Animals; Antipyrine; Blood-Brain Barrier; Brain; Brain Edema; Brain Ischemia; Chromones; Cyclopropanes; Dose-Response Relationship, Drug; Edaravone; Free Radical Scavengers; Infarction, Middle Cerebral Artery; Leukotriene Antagonists; Mice; Nervous System; Neuroprotective Agents; Psychomotor Performance; Quinolines; Receptors, Leukotriene; Sulfides; Survival Analysis; Time Factors | 2005 |
Asthma update: Part II. Medical management.
Topics: Acetates; Adrenergic beta-Agonists; Anti-Bacterial Agents; Asthma; Child; Cyclopropanes; Drug Therapy, Combination; Glucocorticoids; Humans; Leukotriene Antagonists; Practice Guidelines as Topic; Quinolines; Respiratory Function Tests; Sulfides | 2004 |
Montelukast modulates lung CysLT(1) receptor expression and eosinophilic inflammation in asthmatic mice.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Cyclopropanes; Eosinophils; Interleukin-5; Leukocyte Count; Leukotriene Antagonists; Lung; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Ovalbumin; Quinolines; Receptors, Leukotriene; RNA, Messenger; Sulfides; Up-Regulation | 2004 |
Comparison study between the mechanisms of allergic asthma amelioration by a cysteinyl-leukotriene type 1 receptor antagonist montelukast and methylprednisolone.
Topics: Acetates; Airway Resistance; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bile; Bronchoalveolar Lavage Fluid; Cyclopropanes; Cysteine; Hypersensitivity; In Vitro Techniques; Leukocyte Count; Leukotriene A4; Leukotriene Antagonists; Leukotrienes; Lung; Methylprednisolone; Quinolines; Rats; Rats, Inbred BN; Receptors, Leukotriene; Sulfides | 2005 |
Novel inhibitory effect on 5-lipoxygenase activity by the anti-asthma drug montelukast.
Topics: Acetates; Allosteric Site; Animals; Anti-Asthmatic Agents; Asthma; Calcimycin; Calcium; Catalysis; Cell Line; Cell Line, Tumor; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclopropanes; Dexamethasone; Dose-Response Relationship, Drug; HL-60 Cells; Humans; Inhibitory Concentration 50; Kinetics; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Mast Cells; Neutrophils; Protein Binding; Quinolines; Rats; Recombinant Proteins; Sulfides | 2004 |
[A case report of systemic capillary leak syndrome. Effective treatment with immunoadsorption and leukotriene antagonist].
Topics: Acetates; Adult; Blood Proteins; Capillary Leak Syndrome; Cyclopropanes; Female; Humans; Immunosorbent Techniques; Leukotriene Antagonists; Quinolines; Sulfides; Treatment Outcome | 2004 |
An automated method for the determination of montelukast in human plasma using dual-column HPLC analysis and peak height summation of the parent compound and its photodegradation product.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Automation; Chromatography, High Pressure Liquid; Cyclopropanes; Drug Stability; Female; Humans; Light; Male; Middle Aged; Molecular Structure; Quinolines; Reproducibility of Results; Sulfides; Therapeutic Equivalency | 2004 |
Comparative cutoff points for adenosine monophosphate and methacholine challenge testing.
Topics: Acetates; Adenosine Monophosphate; Administration, Inhalation; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Cyclopropanes; Forced Expiratory Volume; Humans; Methacholine Chloride; Quinolines; Retrospective Studies; Sulfides | 2004 |
Observational study of the effects of using montelukast vs fluticasone in patients matched at baseline.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Androstadienes; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Child; Child, Preschool; Cohort Studies; Cyclopropanes; Female; Fluticasone; Hospitalization; Humans; Insurance Claim Review; Leukotriene Antagonists; Male; Managed Care Programs; Middle Aged; Quinolines; Retrospective Studies; Sulfides; Treatment Outcome | 2004 |
Cysteinyl leukotriene receptor antagonist regulates vascular permeability by reducing vascular endothelial growth factor expression.
Topics: Acetates; Animals; Bronchial Hyperreactivity; Capillary Permeability; Chromones; Cyclopropanes; Cytokines; Female; Indoles; Membrane Proteins; Mice; Mice, Inbred BALB C; NF-kappa B; Ovalbumin; Quinolines; Receptors, Leukotriene; Receptors, Vascular Endothelial Growth Factor; Sulfides; Transcription Factor RelA; Vascular Endothelial Growth Factor A | 2004 |
Weaving a blanket to protect the entire airway: the goal of comprehensive therapy.
Topics: Acetates; Allergens; Animals; Cats; Cyclopropanes; Humans; Hypersensitivity; Quinolines; Respiratory Tract Diseases; Sulfides | 2004 |
Treatment of chronic cough in children with montelukast,a leukotriene receptor antagonist.
Topics: Acetates; Biomarkers; Chronic Disease; Cough; Cyclopropanes; Dose-Response Relationship, Drug; Drug Administration Schedule; Eosinophil Cationic Protein; Eosinophils; Female; Follow-Up Studies; Humans; Immunoglobulin E; Leukotriene Antagonists; Male; Probability; Prospective Studies; Quinolines; Risk Assessment; Severity of Illness Index; Sulfides; Treatment Outcome | 2004 |
Gastroprotective effect of leukotriene receptor blocker montelukast in alendronat-induced lesions of the rat gastric mucosa.
Topics: Acetates; Alendronate; Animals; Cyclopropanes; Female; Gastric Acidity Determination; Gastric Mucosa; Glutathione; Hydrogen-Ion Concentration; Kidney; Leukotriene Antagonists; Liver; Male; Malondialdehyde; Peroxidase; Quinolines; Rats; Rats, Wistar; Stomach Ulcer; Sulfides | 2005 |
[Effect of montelukast on the apoptosis of lymphocytes in asthmatic rats and its molecular mechanism].
Topics: Acetates; Animals; Anti-Asthmatic Agents; Apoptosis; Asthma; CD4-Positive T-Lymphocytes; Cells, Cultured; Cyclopropanes; Male; Ovalbumin; Quinolines; Random Allocation; Rats; Rats, Sprague-Dawley; Sulfides | 2003 |
Selective inhibition of human cytochrome P4502C8 by montelukast.
Topics: Acetates; Amodiaquine; Anti-Asthmatic Agents; Aryl Hydrocarbon Hydroxylases; Cyclopropanes; Cytochrome P-450 CYP2C8; Drug Interactions; Enzyme Inhibitors; Humans; In Vitro Techniques; Leukotriene Antagonists; Microsomes, Liver; Paclitaxel; Quinolines; Recombinant Proteins; Rosiglitazone; Sulfides; Thiazolidinediones | 2005 |
Effect of fluticasone propionate and salmeterol in a single device, fluticasone propionate, and montelukast on overall asthma control, exacerbations, and costs.
Topics: Acetates; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Clinical Trials as Topic; Cost of Illness; Cyclopropanes; Drug Combinations; Fluticasone; Humans; Middle Aged; Quinolines; Salmeterol Xinafoate; Sulfides | 2004 |
The national montelukast survey.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cross-Sectional Studies; Cyclopropanes; Demography; Female; Humans; Male; Middle Aged; Quinolines; Retrospective Studies; Sulfides; Surveys and Questionnaires; Treatment Outcome; United Kingdom | 2005 |
[Effect of the leukotriene receptor antagonist montelukast therapy on asthma in childhood].
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Drug Administration Schedule; Female; Humans; Leukotriene Antagonists; Male; Quinolines; Severity of Illness Index; Sulfides; Surveys and Questionnaires; Time Factors; Treatment Outcome | 2004 |
Biological effects of montelukast, a cysteinyl-leukotriene receptor-antagonist, on T lymphocytes.
Topics: Acetates; Anti-Inflammatory Agents; Apoptosis; Cell Proliferation; Clone Cells; Cyclopropanes; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Humans; Interferon-gamma; Interleukin-4; Jurkat Cells; Lymphocyte Activation; Membrane Proteins; Oligonucleotide Array Sequence Analysis; Quinolines; Receptors, Leukotriene; Sulfides; T-Lymphocytes; Transcriptional Activation | 2004 |
[Value of leukotriene antagonists in bronchial asthma].
Topics: Acetates; Airway Obstruction; Asthma; Bronchial Hyperreactivity; Cyclopropanes; Eosinophilia; Humans; Leukotriene Antagonists; Quinolines; Respiratory Hypersensitivity; Sulfides; Treatment Outcome | 2004 |
[Effects of montelukast on apoptosis and Fas mRNA expression of eosinophils in airway of asthmatic guinea pigs].
Topics: Acetates; Animals; Anti-Asthmatic Agents; Apoptosis; Asthma; Cyclopropanes; Eosinophils; fas Receptor; Female; Guinea Pigs; Leukotriene Antagonists; Male; Ovalbumin; Quinolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfides | 2004 |
The effect of montelukast on exhaled nitric oxide and lung function in asthmatic children 2 to 5 years old.
Topics: Acetates; Airway Resistance; Anti-Asthmatic Agents; Asthma; Breath Tests; Bronchodilator Agents; Child, Preschool; Cyclopropanes; Female; Genetic Predisposition to Disease; Humans; Leukotriene Antagonists; Male; Nitric Oxide; Quinolines; Radioallergosorbent Test; Respiratory Hypersensitivity; Sulfides; Terbutaline; Treatment Outcome | 2005 |
The effect of treatment with montelukast on in vitro interleukin-10 production of mononuclear cells of children with asthma.
Topics: Acetates; Adolescent; Analysis of Variance; Asthma; Child; Cyclopropanes; Eosinophils; Female; Forced Expiratory Volume; Humans; Hypersensitivity; Interleukin-10; Leukocyte Count; Leukocytes, Mononuclear; Leukotriene Antagonists; Lung; Male; Quinolines; Seasons; Sulfides; Treatment Outcome | 2005 |
Outcomes associated with initiation of different controller therapies in a Medicaid asthmatic population: a retrospective data analysis.
Topics: Acetates; Adolescent; Adrenergic beta-Agonists; Adult; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Cohort Studies; Cyclopropanes; Drug Therapy, Combination; Female; Fluticasone; Health Care Costs; Humans; Leukotriene Antagonists; Male; Medicaid; Patient Compliance; Quinolines; Retrospective Studies; Salmeterol Xinafoate; Sulfides; Treatment Outcome | 2005 |
Exhaled breath condensate cysteinyl leukotrienes are increased in children with exercise-induced bronchoconstriction.
Topics: Acetates; Adolescent; Ammonia; Asthma, Exercise-Induced; Biomarkers; Breath Tests; Bronchoconstriction; Child; Cyclopropanes; Cysteine; Exhalation; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Leukotriene B4; Leukotrienes; Nitric Oxide; Quinolines; Respiratory Function Tests; Sulfides | 2005 |
[Preventive effects of montelukast on the collagen expression of pulmonary arterioles in rats with chronic hypoxia].
Topics: Acetates; Animals; Arterioles; Collagen Type I; Cyclopropanes; Hypertension, Pulmonary; Hypoxia; Leukotriene Antagonists; Male; Pulmonary Artery; Quinolines; Random Allocation; Rats; Rats, Wistar; Sulfides | 2005 |
Salmeterol/fluticasone propionate versus fluticasone propionate plus montelukast: a cost-effective comparison for asthma.
Topics: Acetates; Adolescent; Adult; Aged; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Cost-Benefit Analysis; Cyclopropanes; Drug Combinations; Drug Therapy, Combination; Fluticasone; Fluticasone-Salmeterol Drug Combination; Humans; Middle Aged; Multicenter Studies as Topic; Netherlands; Quinolines; Randomized Controlled Trials as Topic; Sulfides | 2005 |
[The effect of montelukast, a leukotriene antagonist, on improvement of exercise-induced bronchoconstriction].
Topics: Acetates; Adolescent; Adult; Asthma, Exercise-Induced; Bronchial Provocation Tests; Bronchoconstriction; Cyclopropanes; Female; Forced Expiratory Volume; Glucocorticoids; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Respiratory Function Tests; Sulfides | 2005 |
Bronchoprotective effects of single doses of salmeterol combined with montelukast in thermally induced bronchospasm.
Topics: Acetates; Adult; Albuterol; Anti-Asthmatic Agents; Bronchodilator Agents; Cyclopropanes; Deglutition Disorders; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Salmeterol Xinafoate; Sulfides; Temperature | 2005 |
Burn-induced oxidative injury of the gut is ameliorated by the leukotriene receptor blocker montelukast.
Topics: Acetates; Animals; Biomarkers; Burns; Cyclopropanes; Glutathione; Intestines; L-Lactate Dehydrogenase; Leukotriene Antagonists; Malondialdehyde; Neutrophils; Oxidative Stress; Quinolines; Rats; Rats, Wistar; Skin; Sulfides; Tumor Necrosis Factor-alpha | 2005 |
Differential effect of zileuton, a 5-lipoxygenase inhibitor, against nociceptive paradigms in mice and rats.
Topics: Acetates; Acetic Acid; Analgesics; Animals; Capillary Permeability; Carrageenan; Cyclopropanes; Dose-Response Relationship, Drug; Female; Hindlimb; Hydroxyurea; Hyperalgesia; Indoles; Inflammation; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Mice; Pain; Pain Measurement; Phenylcarbamates; Quinolines; Rats; Rats, Wistar; Receptors, Leukotriene B4; Sulfides; Sulfonamides; Tosyl Compounds | 2005 |
Leukotriene receptor blocker montelukast protects against burn-induced oxidative injury of the skin and remote organs.
Topics: Acetates; Animals; Blood Urea Nitrogen; Burns; Cyclopropanes; Enzymes; Female; Glutathione; Kidney; Leukotriene Antagonists; Liver; Lung; Male; Malondialdehyde; Neutrophils; Oxidative Stress; Quinolines; Rats; Rats, Wistar; Skin; Sulfides; Tumor Necrosis Factor-alpha | 2005 |
Leukotriene inhibitors in combination with steroids: potential role in the development of primary bacterial peritonitis.
Topics: Acetates; Aged; Anti-Inflammatory Agents; Asthma; Cyclopropanes; Drug Therapy, Combination; Escherichia coli Infections; Female; Humans; Leukotriene Antagonists; Peritoneal Lavage; Peritonitis; Prednisolone; Quinolines; Sulfides | 2005 |
State and trait anxiety in patients affected by nasal polyposis before and after medical treatment.
Topics: Acetates; Administration, Intranasal; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Anxiety; Cyclopropanes; Depression; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Mometasone Furoate; Nasal Polyps; Pregnadienediols; Quinolines; Severity of Illness Index; Sulfides; Surveys and Questionnaires; Time Factors | 2004 |
Increased risk of asthma attacks and emergency visits among asthma patients with allergic rhinitis: a subgroup analysis of the investigation of montelukast as a partner agent for complementary therapy [corrected].
Topics: Acetates; Administration, Inhalation; Adult; Albuterol; Androstadienes; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Cyclopropanes; Double-Blind Method; Emergencies; Female; Fluticasone; Humans; Male; Patient Acceptance of Health Care; Quinolines; Rhinitis, Allergic, Perennial; Risk Factors; Salmeterol Xinafoate; Sulfides | 2005 |
Improving asthma control in patients suboptimally controlled on inhaled steroids and long-acting beta2-agonists: addition of montelukast in an open-label pilot study.
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Anti-Asthmatic Agents; Asthma; Belgium; Cyclopropanes; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pilot Projects; Quinolines; Sulfides; Surveys and Questionnaires | 2005 |
Effect of montelukast on nuclear factor kappaB activation and proinflammatory molecules.
Topics: Acetates; Anti-Inflammatory Agents; Cell Line, Tumor; Chemokine CCL2; Cyclopropanes; Dose-Response Relationship, Drug; Humans; Inflammation Mediators; Interleukin-6; Leukocytes, Mononuclear; Leukotriene Antagonists; NF-kappa B; Quinolines; Sulfides; Tumor Necrosis Factor-alpha | 2005 |
Effects of montelukast in patients with persistent asthma using inhaled corticosteroids plus additional second-line therapy.
Topics: Acetates; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Nebulizers and Vaporizers; Quinolines; Sulfides; Treatment Outcome | 2005 |
[Churg-Strauss syndrome relapse when antileucotriene in taggered].
Topics: Acetates; Adrenal Cortex Hormones; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Radiography, Thoracic; Recurrence; Sulfides; Time Factors; Tomography, X-Ray Computed | 2005 |
Eosinophilic gastroenteritis in a young girl--long term remission under Montelukast.
Topics: Acetates; Adolescent; Cyclopropanes; Eosinophilia; Female; Gastroenteritis; Humans; Leukotriene Antagonists; Quinolines; Remission Induction; Sulfides | 2005 |
Is it time to consider a new treatment for children with sleep-disordered breathing?
Topics: Acetates; Child; Child, Preschool; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Sleep Apnea Syndromes; Sulfides; Treatment Outcome | 2005 |
Usefulness of montelukast to prevent adverse reactions to COX-2 selective inhibitors: a case report.
Topics: Acetates; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Cyclopropanes; Drug Hypersensitivity; Female; Humans; Middle Aged; Quinolines; Sulfides | 2005 |
Treatment of mild asthma.
Topics: Acetates; Adrenal Cortex Hormones; Adult; Albuterol; Anti-Asthmatic Agents; Asthma; Budesonide; Child; Cyclopropanes; Drug Administration Schedule; Humans; Quinolines; Sulfides | 2005 |
When an asthma drug has an inferiority complex: a noninferiority trial.
Topics: Acetates; Administration, Inhalation; Adolescent; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Child; Cyclopropanes; Fluticasone; Humans; Leukotriene Antagonists; Quinolines; Research Design; Sulfides | 2005 |
Bradykinin and tachykinin-induced leukotriene release in airway virus infections.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Bradykinin; Child, Preschool; Cyclopropanes; Humans; Leukotrienes; Quinolines; Sulfides; Tachykinins; Virus Diseases | 2005 |
Asthma rescue and allergy medication use among asthmatic children with prior allergy prescriptions who initiated asthma controller therapy.
Topics: Acetates; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Child; Cohort Studies; Cyclopropanes; Drug Costs; Drug Prescriptions; Female; Humans; Longitudinal Studies; Male; Multivariate Analysis; Quinolines; Regression Analysis; Retrospective Studies; Rhinitis, Allergic, Perennial; Sulfides | 2005 |
Adherence to asthma controller medication regimens.
Topics: Acetates; Administration, Inhalation; Adult; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Cohort Studies; Cyclopropanes; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluticasone; Humans; Male; Middle Aged; Nebulizers and Vaporizers; Patient Compliance; Quinolines; Retrospective Studies; Salmeterol Xinafoate; Sulfides | 2005 |
Montelukast for viral respiratory infection-induced exacerbations of asthma.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Quinolines; Respiratory Tract Infections; Sulfides; Virus Diseases | 2005 |
Amelioration of sepsis-induced hepatic and ileal injury in rats by the leukotriene receptor blocker montelukast.
Topics: Acetates; Animals; Cecum; Collagen; Cyclopropanes; Glutathione; Ileal Diseases; Ileum; L-Lactate Dehydrogenase; Leukotriene Antagonists; Ligation; Liver; Liver Diseases; Luminescent Measurements; Malondialdehyde; Peroxidase; Quinolines; Rats; Rats, Wistar; Sepsis; Sulfides; Tumor Necrosis Factor-alpha | 2005 |
[Nose and lung breathe the same air].
Topics: Acetates; Asthma; Cyclopropanes; Desensitization, Immunologic; Diagnosis, Differential; Humans; Leukotrienes; Nursing Diagnosis; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides | 2005 |
[One tablet daily against asthma and allergic rhinitis].
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Asthma; Clinical Trials as Topic; Cyclopropanes; Delayed-Action Preparations; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lung Volume Measurements; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides | 2005 |
[The role of leukotriene D4 antagonist in allergic rhinitis with steroid resistance].
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Aged; Child; Child, Preschool; Cyclopropanes; Female; Glucocorticoids; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Rhinitis, Allergic, Perennial; Sulfides | 2005 |
Successful treatment of severe atopic dermatitis with cysteinyl leukotriene receptor antagonist montelukast.
Topics: Acetates; Adult; Cyclopropanes; Dermatitis, Atopic; Female; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2005 |
Antileukotriene treatment and allergic rhinitis-related cough in guinea pigs.
Topics: Acetates; Administration, Oral; Animals; Citric Acid; Cough; Cyclopropanes; Disease Models, Animal; Guinea Pigs; Laryngeal Mucosa; Leukotriene Antagonists; Male; Membrane Proteins; Ovalbumin; Quinolines; Receptors, Leukotriene; Rhinitis, Allergic, Perennial; Sulfides; Time Factors | 2005 |
CysLT1 leukotriene receptor antagonists inhibit the effects of nucleotides acting at P2Y receptors.
Topics: Acetates; Base Sequence; Calcium; Chromones; Cyclopropanes; DNA Primers; Humans; Membrane Proteins; Quinolines; Receptors, Leukotriene; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sulfides; U937 Cells; Uridine Triphosphate | 2005 |
Influence of leukotriene pathway polymorphisms on response to montelukast in asthma.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Female; Gene Frequency; Genotype; Humans; Leukotrienes; Male; Polymorphism, Genetic; Quinolines; Sulfides | 2006 |
Asthma-related health care resource use among patients starting fluticasone or montelukast therapy.
Topics: Acetates; Adolescent; Adult; Androstadienes; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cohort Studies; Cyclopropanes; Female; Fluticasone; Health Services; Humans; Male; Middle Aged; Quinolines; Retrospective Studies; Sulfides | 2005 |
The cysteinyl-leukotriene-1 receptor antagonist zafirlukast is a potent secretagogue in rat and human airways.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetates; Animals; Arachidonic Acid; Bronchi; Chromones; Cyclooxygenase Inhibitors; Cyclopropanes; Dose-Response Relationship, Drug; Humans; Ibuprofen; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Membrane Proteins; Morpholines; Phenylcarbamates; Phosphoinositide-3 Kinase Inhibitors; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds; Trachea | 2005 |
Spectrofluorometric determination of montelukast in dosage forms and spiked human plasma.
Topics: Acetates; Anti-Asthmatic Agents; Chromatography, High Pressure Liquid; Cyclopropanes; Dosage Forms; Indicators and Reagents; Linear Models; Quinolines; Reproducibility of Results; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Sulfides; Tablets | 2005 |
Ribavirin and cysteinyl leukotriene-1 receptor blockade as treatment for severe bronchiolitis.
Topics: Acetates; Animals; Antiviral Agents; Bronchiolitis, Viral; Cyclopropanes; Cysteine; Disease Models, Animal; Drug Therapy, Combination; Humans; Leukotriene Antagonists; Leukotrienes; Lung; Mice; Mice, Inbred C57BL; Murine pneumonia virus; Pneumovirus Infections; Quinolines; Ribavirin; Sulfides; Treatment Outcome; Virus Replication | 2006 |
Reversal of allergen-induced airway remodeling by CysLT1 receptor blockade.
Topics: Acetates; Animals; Asthma; Cyclopropanes; Disease Models, Animal; Female; Follow-Up Studies; Glucocorticoids; Leukotriene Antagonists; Lung; Membrane Proteins; Mice; Mice, Inbred BALB C; Muscle, Smooth; Quinolines; Receptors, Leukotriene; Respiratory Mucosa; Sulfides; Treatment Outcome | 2006 |
Intranasal steroids and oral leukotriene modifier therapy in residual sleep-disordered breathing after tonsillectomy and adenoidectomy in children.
Topics: Acetates; Adenoidectomy; Administration, Intranasal; Administration, Oral; Budesonide; Child; Cyclopropanes; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Leukotriene Antagonists; Male; Polysomnography; Quinolines; Sleep Apnea Syndromes; Sulfides; Tonsillectomy | 2006 |
Fibrodysplasia ossificans progressiva: case report.
Topics: Acetates; Adrenal Cortex Hormones; Child; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Myositis Ossificans; Quinolines; Sulfides; Tomography, X-Ray Computed | 2005 |
Assessing the role of antiinflammatory medications in children with mild sleep-disordered breathing.
Topics: Acetates; Anti-Inflammatory Agents; Budesonide; Child; Cyclopropanes; Humans; Leukotriene Antagonists; Polysomnography; Quinolines; Severity of Illness Index; Sleep Apnea Syndromes; Sulfides; Treatment Outcome | 2006 |
"Inferiority complex" for a reason.
Topics: Acetates; Adolescent; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Child; Cyclopropanes; Fluticasone; Forced Expiratory Volume; Humans; Quinolines; Sulfides | 2006 |
Multimodality measurements of small airways disease.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Quinolines; Respiratory Function Tests; Sulfides; Tomography, X-Ray Computed | 2006 |
Eosinophilic cystitis: successful long-term treatment with montelukast sodium.
Topics: Acetates; Child; Cyclopropanes; Cystitis; Eosinophilia; Humans; Leukotriene Antagonists; Male; Quinolines; Remission Induction; Sulfides; Time Factors | 2006 |
Invalid and irrelevant comparisons: apples or oranges?
Topics: Acetates; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Cost-Benefit Analysis; Cyclopropanes; Drug Combinations; Fluticasone-Salmeterol Drug Combination; Humans; Leukotriene Antagonists; Quinolines; Randomized Controlled Trials as Topic; Respiratory Function Tests; Sulfides | 2006 |
Comparing outcomes in patients with persistent asthma: a registry of two therapeutic alternatives.
Topics: Acetates; Adolescent; Adult; Aged; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Cyclopropanes; Drug Therapy, Combination; Emergency Service, Hospital; Female; Fluticasone; Humans; Male; Middle Aged; Multivariate Analysis; Patient Satisfaction; Prospective Studies; Quality of Life; Quinolines; Registries; Salmeterol Xinafoate; Sulfides; Surveys and Questionnaires; Treatment Outcome | 2006 |
Montelukast protects against renal ischemia/reperfusion injury in rats.
Topics: Acetates; Animals; Blood Urea Nitrogen; Creatinine; Cyclopropanes; Glutathione; Interleukin-1; Interleukin-6; Kidney; L-Lactate Dehydrogenase; Leukotriene Antagonists; Leukotriene B4; Male; Malondialdehyde; Neutrophil Infiltration; Peroxidase; Quinolines; Rats; Rats, Wistar; Reperfusion Injury; Sulfides; Tumor Necrosis Factor-alpha | 2006 |
Exhaled breath condensate cysteinyl leukotrienes and airway remodeling in childhood asthma: a pilot study.
Topics: Acetates; Adolescent; Asthma; Basement Membrane; Bronchi; Child; Child, Preschool; Cyclopropanes; Cysteine; Exhalation; Female; Humans; Leukotrienes; Male; Pilot Projects; Quinolines; Sulfides | 2006 |
[Airway diseases--leukotriene antagonist kills two flies with one fly-flap].
Topics: Acetates; Administration, Inhalation; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchodilator Agents; Budesonide; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Humans; Leukotriene Antagonists; Quinolines; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Seasonal; Sulfides; Time Factors | 2006 |
Expression of urocortin in rat lung and its effect on pulmonary vascular permeability.
Topics: Acetates; Administration, Inhalation; Aerosols; Animals; Blotting, Western; Bronchi; Capillary Permeability; Corticotropin-Releasing Hormone; Cromolyn Sodium; Cyclopropanes; Epithelium; Histamine H1 Antagonists; Immunohistochemistry; Leukotriene Antagonists; Lung; Male; Mast Cells; Ovalbumin; Peptide Fragments; Phthalazines; Pulmonary Alveoli; Quinolines; Rats; Rats, Sprague-Dawley; Respiratory Mucosa; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfides; Urocortins | 2006 |
Montelukast in general pediatric practices.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Dermatitis, Atopic; Family Practice; Humans; Leukotriene Antagonists; Pediatrics; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides | 2005 |
Suppressive effect of verproside isolated from Pseudolysimachion longifolium on airway inflammation in a mouse model of allergic asthma.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Cyclopropanes; Disease Models, Animal; Female; Glucosides; Immunoglobulin E; Interleukin-13; Interleukin-4; Iridoid Glucosides; Iridoids; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Molecular Structure; Mucus; Ovalbumin; Plant Extracts; Pneumonia; Pulmonary Eosinophilia; Quinolines; Sulfides; Veronica | 2006 |
[Churg-Strauss syndrome--a case report].
Topics: Acetates; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Antihypertensive Agents; Churg-Strauss Syndrome; Combined Modality Therapy; Cyclopropanes; Female; Humans; Hypertension; Methylprednisolone; Middle Aged; Quinolines; Sulfides | 2006 |
The effects of low dose leukotriene receptor antagonist therapy on airway remodeling and cysteinyl leukotriene expression in a mouse asthma model.
Topics: Acetates; Airway Obstruction; Animals; Anti-Asthmatic Agents; Asthma; Collagen; Cyclopropanes; Cysteine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Goblet Cells; Hyperplasia; Hypertrophy; Leukotriene Antagonists; Leukotrienes; Lung; Mice; Mice, Inbred BALB C; Mucus; Muscle, Smooth; Pulmonary Fibrosis; Quinolines; Receptors, Leukotriene; Respiratory Mucosa; Sulfides | 2006 |
Effect of montelukast on lung function in asthma patients with allergic rhinitis: analysis from the COMPACT trial.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchodilator Agents; Budesonide; Cyclopropanes; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Lung; Male; Peak Expiratory Flow Rate; Quinolines; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sulfides | 2006 |
Distinct roles of CysLT1 and CysLT2 receptors in oxygen glucose deprivation-induced PC12 cell death.
Topics: Acetates; Animals; Bisbenzimidazole; Cell Death; Cyclopropanes; Flow Cytometry; Glucose; Hypoxia-Ischemia, Brain; Membrane Proteins; Mice; PC12 Cells; Quinolines; Rats; Receptors, Leukotriene; SRS-A; Sulfides | 2006 |
Effects of leukotriene receptor antagonists on monocyte chemotaxis, p38 and cytoplasmic calcium.
Topics: Acetates; Anti-Asthmatic Agents; Blotting, Western; Calcium; Cell Separation; Chemotaxis; Cyclopropanes; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Fetal Blood; Flow Cytometry; Humans; Indoles; Intracellular Fluid; Leukotriene Antagonists; Monocytes; p38 Mitogen-Activated Protein Kinases; Phenylcarbamates; Photometry; Pregnancy; Quinolines; Reference Values; Sulfides; Sulfonamides; Time Factors; Tosyl Compounds | 2006 |
Differential effects of salbutamol and montelukast on eosinophil adhesion and superoxide anion generation.
Topics: Acetates; Adrenergic beta-Agonists; Adult; Albuterol; Cell Adhesion; Cells, Cultured; Cyclopropanes; Eosinophils; Female; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides; Superoxides | 2006 |
Administrative claims analysis of asthma-related health care utilization for patients who received inhaled corticosteroids with either montelukast or salmeterol as combination therapy.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Albuterol; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cohort Studies; Cyclopropanes; Drug Therapy, Combination; Emergency Medical Services; Female; Glucocorticoids; Health Services; Hospitalization; Humans; Insurance Claim Review; Male; Middle Aged; Quinolines; Retrospective Studies; Salmeterol Xinafoate; Sulfides | 2006 |
PP-ICONS--another tool to help interpret asthma utilization studies.
Topics: Abstracting and Indexing; Acetates; Albuterol; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Drug Therapy, Combination; Glucocorticoids; Health Services; Humans; Quinolines; Retrospective Studies; Salmeterol Xinafoate; Sulfides | 2006 |
More evolution of the evidence in asthma disease management--SMART versus GOAL clinical trials debate the cost-benefit of LABA while the value of leukotriene modifiers, particularly montelukast, is uncertain.
Topics: Acetates; Adrenergic beta-Agonists; Asthma; Clinical Trials as Topic; Cost-Benefit Analysis; Cyclopropanes; Delayed-Action Preparations; Disease Management; Emergency Medical Services; Glucocorticoids; Hospitalization; Humans; Insurance Claim Review; Leukotriene Antagonists; Quinolines; Sulfides | 2006 |
Montelukast exerts no acute direct effect on NO synthases.
Topics: Acetates; Animals; Aorta, Thoracic; Cyclopropanes; Dose-Response Relationship, Drug; Female; Gene Expression; Humans; In Vitro Techniques; Leukotriene Antagonists; Lipopolysaccharides; Lung; Male; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Penis; Quinolines; Rabbits; Rats; Rats, Wistar; Sulfides; Vascular Resistance; Vasoconstriction; Vasodilation | 2007 |
Montelukast regulates eosinophil protease activity through a leukotriene-independent mechanism.
Topics: Acetates; Adult; Arachidonic Acids; Cell Movement; Cyclopropanes; Cysteine; Enzyme Activation; Eosinophils; Female; Humans; Indoles; Leukotriene Antagonists; Leukotrienes; Male; Matrix Metalloproteinase 9; Quinolines; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Sulfides; Urokinase-Type Plasminogen Activator | 2006 |
Evaluating the effects of "triple therapy" with inhaled corticosteroids, long-acting beta2-agonists, and leukotriene modifiers in asthma.
Topics: Acetates; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Drug Therapy, Combination; Humans; Leukotriene Antagonists; Peak Expiratory Flow Rate; Quinolines; Sulfides | 2006 |
Patterns of asthma-related health care resource use in children treated with montelukast or fluticasone.
Topics: Acetates; Adolescent; Androstadienes; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Delivery of Health Care; Emergency Medical Services; Female; Fluticasone; Humans; Male; Medication Systems; Pharmaceutical Services; Quinolines; Retrospective Studies; Sulfides | 2006 |
Effects of long-term low-dose corticosteroid therapy on humoral immunity.
Topics: Acetates; Agammaglobulinemia; Albuterol; Anti-Asthmatic Agents; Antibodies, Bacterial; Antibody Formation; Asthma; B-Lymphocytes; Cyclopropanes; Drug Therapy, Combination; Female; Humans; Immunoglobulin G; Immunologic Memory; Lymphopenia; Methylprednisolone; Middle Aged; Nasal Polyps; Pneumococcal Vaccines; Quinolines; Sinusitis; Sulfides; T-Lymphocyte Subsets | 2006 |
Montelukast prevents the decrease of interleukin-10 and inhibits NF-kappaB activation in inflammatory airway of asthmatic guinea pigs.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Cyclopropanes; Eosinophils; Guinea Pigs; Interleukin-10; Leukocyte Count; Leukotriene Antagonists; Lung; Male; NF-kappa B; Quinolines; Sulfides | 2006 |
Leukotriene receptor antagonists as potential steroid sparing agents in a patient with serosal eosinophilic gastroenteritis.
Topics: Acetates; Adolescent; Cyclopropanes; Eosinophilia; Gastroenteritis; Glucocorticoids; Humans; Leukotriene Antagonists; Male; Prednisolone; Quinolines; Recurrence; Sulfides | 2006 |
Systemic reaction to omalizumab.
Topics: Acetates; Adrenal Cortex Hormones; Aged; Albuterol; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis; Asthma; Cyclopropanes; Depression; Drug Hypersensitivity; Drug Therapy, Combination; Epinephrine; Female; Humans; Hypersensitivity; Hypertension; Methylprednisolone; Omalizumab; Quinolines; Rhinitis; Salmeterol Xinafoate; Seizures; Sulfides; Syncope | 2006 |
Pathophysiological role of mast cells in collagen-induced arthritis: study with a cysteinyl leukotriene receptor antagonist, montelukast.
Topics: Acetates; Animals; Arthritis, Experimental; Cyclopropanes; Leukotriene Antagonists; Male; Mast Cells; Mice; Mice, Inbred DBA; Quinolines; RNA, Messenger; Stem Cell Factor; Sulfides; Tumor Necrosis Factor-alpha | 2006 |
Urine leukotriene E4 levels are associated with decreased pulmonary function in children with persistent airway obstruction.
Topics: Acetates; Adolescent; Airway Obstruction; Albuterol; Asthma; Child; Chronic Disease; Cyclopropanes; Disease Susceptibility; Female; Forced Expiratory Volume; Humans; Leukotriene E4; Male; Quinolines; Severity of Illness Index; Sulfides | 2006 |
Irrational combination of montelukast and bambuterol for management of childhood asthma.
Topics: Acetates; Asthma; Bronchodilator Agents; Child; Cyclopropanes; Drug Approval; Drug Combinations; Drug Industry; Humans; Leukotriene Antagonists; Quinolines; Sulfides; Terbutaline | 2006 |
Eosinophilic esophagitis.
Topics: Acetates; Adult; Androstadienes; Anti-Inflammatory Agents; Biopsy; Cyclopropanes; Diagnosis, Differential; Drug Therapy, Combination; Endoscopy, Gastrointestinal; Eosinophilia; Esophagitis; Fluticasone; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2006 |
Montelukast is an effective monotherapy for mild asthma and for asthma with co-morbid allergic rhinitis.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Child, Preschool; Clinical Trials as Topic; Cyclopropanes; Humans; Practice Guidelines as Topic; Quinolines; Sulfides | 2006 |
Adenosine A1 receptor antagonist versus montelukast on airway reactivity and inflammation.
Topics: Acetates; Adenosine A1 Receptor Antagonists; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cyclopropanes; Disease Models, Animal; Eosinophils; Histamine; Inflammation; Leukotriene Antagonists; Lung Compliance; Lymphocytes; Macrophages, Alveolar; Neutrophils; Purines; Pyroglyphidae; Quinolines; Rabbits; Sulfides; Time Factors | 2006 |
Effect of montelukast on bacterial sinusitis in allergic mice.
Topics: Acetates; Animals; Cyclopropanes; Female; Flow Cytometry; Hypersensitivity; Leukotriene Antagonists; Male; Mice; Mice, Inbred BALB C; Nasal Lavage Fluid; Ovalbumin; Pneumococcal Infections; Quinolines; Sinusitis; Streptococcus pneumoniae; Sulfides | 2006 |
Allergens induce enhanced bronchoconstriction and leukotriene production in C5 deficient mice.
Topics: Acetates; Allergens; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Choline; Cockroaches; Complement C5; Cyclopropanes; Disease Models, Animal; Dust; Genetic Predisposition to Disease; Immunoglobulin E; Interleukin-12; Leukotriene Antagonists; Leukotrienes; Mice; Mice, Knockout; Quinolines; Respiratory Hypersensitivity; Sulfides | 2006 |
The use of rhinitis medications in children receiving initial controller therapy for asthma.
Topics: Acetates; Administration, Intranasal; Adolescent; Adrenal Cortex Hormones; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Child; Child, Preschool; Cyclopropanes; Drug Combinations; Drug Prescriptions; Fluticasone; Fluticasone-Salmeterol Drug Combination; Histamine H1 Antagonists, Non-Sedating; Humans; Hypersensitivity; Leukotriene Antagonists; Quinolines; Retrospective Studies; Rhinitis; Sulfides | 2006 |
Association between leukotriene C4 synthase A-444C polymorphism and asthma in Chinese Han population in Beijing.
Topics: Acetates; Adult; Alleles; Asian People; Asthma; China; Cyclopropanes; Female; Genotype; Glutathione Transferase; Humans; Male; Middle Aged; Polymorphism, Genetic; Quinolines; Sulfides | 2006 |
Complexation study of cinalukast and montelukast with cyclodextrines.
Topics: Acetates; Calibration; Cyclodextrins; Cyclopropanes; Excipients; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Leukotriene Antagonists; Models, Molecular; Quinolines; Reference Standards; Spectrometry, Fluorescence; Sulfides; Thiazoles | 2007 |
Asthma and allergy medication use and costs among pediatric primary care patients on asthma controller therapy.
Topics: Acetates; Adolescent; Anti-Allergic Agents; Anti-Asthmatic Agents; Child; Cohort Studies; Cyclopropanes; Drug Costs; Drug Prescriptions; Female; Humans; Male; Quinolines; Retrospective Studies; Rhinitis; Steroids; Sulfides; Treatment Outcome | 2006 |
Effects of KP-496, a novel dual antagonist for leukotriene D4 and thromboxane A2 receptors, on contractions induced by various agonists in the guinea pig trachea.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetates; Acetylcholine; Albuterol; Animals; Atropine; Benzoquinones; Carbachol; Chromones; Cyclopropanes; Dinoprost; Drug Evaluation, Preclinical; Guinea Pigs; Heptanoic Acids; Histamine; In Vitro Techniques; Indoles; Indomethacin; Ketanserin; Ketotifen; Leukotriene Antagonists; Leukotriene D4; Male; Muscle Contraction; Muscle, Smooth; Phenylcarbamates; Powders; Procaterol; Prostaglandin Antagonists; Prostaglandin D2; Quinolines; Receptors, Thromboxane A2, Prostaglandin H2; Serotonin; Substance P; Sulfides; Sulfonamides; Tosyl Compounds; Trachea; Tryptophan | 2006 |
Inhibitory effects of angiotensin II receptor antagonists and leukotriene receptor antagonists on the transport of human organic anion transporter 4.
Topics: Acetates; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biological Transport; Biphenyl Compounds; Blotting, Western; Cell Line; Chromones; Cyclopropanes; Dose-Response Relationship, Drug; Estrone; Humans; Imidazoles; Indoles; Leukotriene Antagonists; Losartan; Molecular Structure; Organic Anion Transporters, Sodium-Independent; Phenylcarbamates; Quinolines; Structure-Activity Relationship; Sulfides; Sulfonamides; Tetrazoles; Tosyl Compounds; Transfection; Tritium; Valine; Valsartan | 2006 |
Treatment and outcomes in patients with asthma and allergic rhinitis in the United kingdom.
Topics: Acetates; Adolescent; Adrenergic beta-Agonists; Adult; Androstadienes; Anti-Asthmatic Agents; Asthma; Beclomethasone; Budesonide; Cohort Studies; Comorbidity; Cyclopropanes; Drug Therapy, Combination; Female; Fluticasone; Humans; Male; Middle Aged; Quinolines; Rhinitis; Sulfides; Treatment Outcome; United Kingdom | 2007 |
Montelukast in the treatment of HIV associated immune reconstitution disease.
Topics: Acetates; Adjuvants, Immunologic; Cyclopropanes; Female; HIV Infections; Humans; Immune System Diseases; Male; Quinolines; Sulfides | 2006 |
Proton magnetic resonance spectroscopy findings and clinical effects of montelukast sodium in a case with Sjögren-Larsson syndrome.
Topics: Acetates; Aldehyde Dehydrogenase; Brain; Child, Preschool; Cyclopropanes; Fatty Acids; Humans; Ichthyosis; Leukotriene Antagonists; Leukotrienes; Lipid Metabolism; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Predictive Value of Tests; Pruritus; Quinolines; Sjogren-Larsson Syndrome; Sulfides; Treatment Outcome | 2006 |
Fatal liver failure following food supplements during chronic treatment with montelukast.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Chemical and Drug Induced Liver Injury; Cyclopropanes; Dietary Supplements; Drug Interactions; Fatal Outcome; Female; Humans; Liver Failure, Acute; Middle Aged; Quinolines; Sulfides | 2007 |
Oxidative renal damage in pyelonephritic rats is ameliorated by montelukast, a selective leukotriene CysLT1 receptor antagonist.
Topics: Acetates; Animals; Blood Urea Nitrogen; Creatinine; Cyclopropanes; Escherichia coli; Female; Glutathione; L-Lactate Dehydrogenase; Leukotriene Antagonists; Lipid Peroxidation; Luminescent Measurements; Male; Malondialdehyde; Membrane Proteins; Peroxidase; Pyelonephritis; Quinolines; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, Leukotriene; Sulfides; Tumor Necrosis Factor-alpha | 2007 |
Effects of long-term treatment with montelukast in mild cystic fibrosis (long term treatment with montelukast in cystic fibrosis).
Topics: Acetates; Adolescent; Child; Cyclopropanes; Cystic Fibrosis; Female; Humans; Leukotriene Antagonists; Long-Term Care; Male; Quinolines; Sulfides; Treatment Outcome | 2007 |
Heterogeneous effect of leucotriene CysLT1 receptor antagonists on antigen-induced motor and inflammatory responses in guinea-pig airways.
Topics: Acetates; Animals; Antigens; Benzopyrans; Bronchoconstriction; Cyclopropanes; Dose-Response Relationship, Drug; Evans Blue; Guinea Pigs; Inflammation; Injections, Intravenous; Leukotriene Antagonists; Male; Membrane Proteins; Ovalbumin; Quinolines; Receptors, Leukotriene; Respiratory System; Sulfides; Tetrazoles | 2007 |
Cysteinyl leukotrienes synergize with growth factors to induce proliferation of human bronchial fibroblasts.
Topics: Acetates; Bronchi; Cell Proliferation; Cells, Cultured; Cyclopropanes; ErbB Receptors; Fibroblasts; Humans; Intercellular Signaling Peptides and Proteins; Leukotriene C4; Leukotriene D4; Membrane Proteins; Propionates; Protein Serine-Threonine Kinases; Quinolines; Receptors, Leukotriene; RNA, Messenger; SRS-A; Sulfides | 2007 |
Cysteinyl leukotriene upregulates IL-11 expression in allergic airway disease of mice.
Topics: Acetates; Animals; Bronchoalveolar Lavage Fluid; Cells, Cultured; Chromones; Collagen; Cyclopropanes; Epithelial Cells; Female; Interleukin-11; Interleukin-13; Interleukin-4; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Lung; Mice; Mice, Inbred C57BL; Nitriles; Ovalbumin; Quinolines; Respiratory Hypersensitivity; RNA, Messenger; Sulfides; Sulfones; Transcription Factor RelA | 2007 |
Histamine, but not leukotriene C4, is an essential mediator in cold urticaria wheals.
Topics: Acetates; Adult; Anti-Allergic Agents; Cetirizine; Cold Temperature; Cyclopropanes; Female; Histamine; Humans; Leukotriene Antagonists; Leukotriene C4; Male; Middle Aged; Quinolines; Sulfides; Urticaria | 2007 |
Comparative efficacy and cost of asthma care in children with asthma treated with fluticasone propionate and montelukast.
Topics: Acetates; Administration, Inhalation; Adolescent; Androstadienes; Asthma; Bronchodilator Agents; Child; Child, Preschool; Cohort Studies; Confidence Intervals; Cost-Benefit Analysis; Cyclopropanes; Female; Fluticasone; Follow-Up Studies; Humans; Male; Odds Ratio; Probability; Quinolines; Respiratory Function Tests; Retrospective Studies; Severity of Illness Index; Sulfides; Treatment Outcome | 2007 |
Successful drug treatment of immune reconstitution disease with the leukotriene receptor antagonist, montelukast: a clue to pathogenesis?
Topics: Acetates; Antiretroviral Therapy, Highly Active; Cyclopropanes; HIV Infections; Humans; Immune System Diseases; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Sulfides; Syndrome | 2007 |
[A rare cause of dysphagia and bolus obstruction in adults].
Topics: Acetates; Adult; Biopsy; Catheterization; Cyclopropanes; Deglutition Disorders; Diagnosis, Differential; Dilatation; Drug Therapy, Combination; Endoscopy, Digestive System; Eosinophilia; Esophageal Stenosis; Esophagitis; Esophagus; Glucocorticoids; Humans; Leukotriene Antagonists; Male; Prednisolone; Quinolines; Sulfides | 2007 |
Montelukast-related Churg-Strauss vasculitis presenting with peripheral neuropathy.
Topics: Acetates; Adult; Churg-Strauss Syndrome; Cyclopropanes; Electromyography; Female; Glucocorticoids; Humans; Leukotriene Antagonists; Peripheral Nervous System Diseases; Quinolines; Sulfides; Treatment Outcome | 2007 |
Sparing effect by montelukast treatment for chronic graft versus host disease: a pilot study.
Topics: Acetates; Administration, Oral; Adolescent; Adult; Chronic Disease; Cyclopropanes; Female; Graft vs Host Disease; Humans; Leukotriene Antagonists; Male; Middle Aged; Pilot Projects; Quinolines; Retrospective Studies; Sulfides; Treatment Outcome | 2007 |
Effect of montelukast in a guinea pig model of cough variant asthma.
Topics: Acetates; Airway Resistance; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cough; Cyclopropanes; Disease Models, Animal; Guinea Pigs; Leukotrienes; Male; Ovalbumin; Quinolines; Sulfides | 2008 |
Asthma control in patients with asthma and allergic rhinitis receiving add-on montelukast therapy for 12 months: a retrospective observational study.
Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Chemotherapy, Adjuvant; Cyclopropanes; Female; Humans; Male; Middle Aged; Quinolines; Retrospective Studies; Rhinitis, Allergic, Seasonal; Sulfides; Treatment Outcome | 2007 |
[Effects of cysteinyl receptor agonist and antagonists on rat primary cortical neurons].
Topics: Acetates; Animals; Animals, Newborn; Calcium; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromones; Cyclopropanes; Glucose; Leukotriene Antagonists; Leukotriene D4; Neurons; Quinolines; Rats; Receptors, Leukotriene; Sulfides | 2007 |
Montelukast and theophylline: no use or some use in persistent asthma?
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Quinolines; Randomized Controlled Trials as Topic; Sulfides; Theophylline | 2007 |
Chronic renal failure-induced multiple-organ injury in rats is alleviated by the selective CysLT1 receptor antagonist montelukast.
Topics: Acetates; Animals; Antioxidants; Apoptosis; Blood Urea Nitrogen; Collagen; Creatinine; Cyclopropanes; Glutathione; Interleukin-1beta; Interleukin-6; Kidney; Kidney Failure, Chronic; L-Lactate Dehydrogenase; Leukocytes; Leukotriene Antagonists; Lung; Male; Malondialdehyde; Membrane Proteins; Multiple Organ Failure; Quinolines; Random Allocation; Rats; Rats, Wistar; Receptors, Leukotriene; Sulfides; Tumor Necrosis Factor-alpha | 2007 |
9 years of recurrent dysphagia.
Topics: Acetates; Cyclopropanes; Deglutition Disorders; Gastroscopy; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Steroids; Sulfides | 2007 |
Overexpression of cysteinyl LT1 receptor in prostate cancer and CysLT1R antagonist inhibits prostate cancer cell growth through apoptosis.
Topics: Acetates; Aged; Apoptosis; Cell Proliferation; Cyclopropanes; Disease Progression; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Immunoenzyme Techniques; Leukotriene Antagonists; Male; Membrane Proteins; Middle Aged; Prostate; Prostatic Hyperplasia; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Quinolines; Receptors, Leukotriene; Sulfides; Tumor Cells, Cultured | 2007 |
Role of cysteinyl leukotrienes in the proliferation and the migration of murine vascular smooth muscle cells in vivo and in vitro.
Topics: Acetates; Animals; Anti-Bacterial Agents; Calcimycin; Cell Movement; Cell Proliferation; Cells, Cultured; Cyclopropanes; Cysteine; Femoral Artery; Leukotriene Antagonists; Leukotrienes; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred C57BL; Models, Animal; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neovascularization, Physiologic; Quinolines; Sulfides; Wound Healing | 2007 |
Lipoxin A4 stable analogs reduce allergic airway responses via mechanisms distinct from CysLT1 receptor antagonism.
Topics: Acetates; Allergens; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Plant; Cyclopropanes; Disease Models, Animal; Leukotriene Antagonists; Lipoxins; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Ovalbumin; Phenyl Ethers; Quinolines; Receptors, Leukotriene; Respiratory Hypersensitivity; Structure-Activity Relationship; Sulfides | 2007 |
The effects of montelukast on tissue inflammatory and bone marrow responses in murine experimental allergic rhinitis: interaction with interleukin-5 deficiency.
Topics: Acetates; Animals; Basophils; Bone Marrow; Colony-Forming Units Assay; Cyclopropanes; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Eosinophils; Hematopoietic Stem Cells; Interleukin-5; Leukotriene Antagonists; Mice; Mice, Inbred BALB C; Nasal Mucosa; Ovalbumin; Quinolines; Rhinitis, Allergic, Perennial; Sulfides | 2007 |
Leukotriene D(4) enhances the function of endothelin-1-primed fibroblasts.
Topics: Acetates; Actins; Cyclopropanes; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Fetus; Fibroblasts; Flow Cytometry; Humans; Leukotriene Antagonists; Leukotriene D4; Lung; Matrix Metalloproteinases; Membrane Proteins; Peptide Fragments; Procollagen; Quinolines; Receptors, Leukotriene; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfides; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor beta1 | 2007 |
Montelukast reduces ischaemia/reperfusion-induced bladder dysfunction and oxidant damage in the rat.
Topics: Acetates; Animals; Cyclopropanes; Female; Glutathione; Isometric Contraction; Leukotriene Antagonists; Lipid Peroxidation; Male; Muscle, Smooth; Oxidative Stress; Peroxidase; Quinolines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sulfides; Urinary Bladder; Urinary Bladder Diseases | 2007 |
Healthcare utilisation and costs associated with adding montelukast to current therapy in patients with mild to moderate asthma and co-morbid allergic rhinitis: PRAACTICAL study.
Topics: Acetates; Adolescent; Adult; Asthma; Cohort Studies; Cyclopropanes; Delivery of Health Care; Female; Health Care Costs; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Retrospective Studies; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sulfides | 2007 |
Montelukast in 2 atopic patients with intolerance to nonsteroidal anti-inflammatory drugs and paracetamol: 5-year follow-up.
Topics: Acetaminophen; Acetates; Adult; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclopropanes; Drug Hypersensitivity; Female; Follow-Up Studies; Humans; Quinolines; Sulfides | 2007 |
A rapid and sensitive method for the quantitation of montelukast in sheep plasma using liquid chromatography/tandem mass spectrometry.
Topics: Acetates; Animals; Chromatography, Liquid; Cyclopropanes; Molecular Structure; Quinolines; Reproducibility of Results; Sheep; Sulfides; Tandem Mass Spectrometry | 2007 |
Effect of light and heat on the stability of montelukast in solution and in its solid state.
Topics: Acetates; Anti-Asthmatic Agents; Buffers; Chromatography, High Pressure Liquid; Cyclopropanes; Drug Stability; Hot Temperature; Hydrogen-Ion Concentration; Light; Molecular Structure; Quinolines; Solutions; Solvents; Sulfides; Tablets | 2007 |
Efficacy of nasal corticosteroids alone or combined with antihistamines or montelukast in treatment of allergic rhinitis.
Topics: Acetates; Administration, Intranasal; Administration, Oral; Adolescent; Adult; Anti-Allergic Agents; Cyclopropanes; Drug Therapy, Combination; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Intradermal Tests; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Mometasone Furoate; Pregnadienediols; Pulmonary Ventilation; Quality of Life; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides | 2008 |
Responsiveness to montelukast is associated with bronchial hyperresponsiveness and total immunoglobulin E but not polymorphisms in the leukotriene C4 synthase and cysteinyl leukotriene receptor 1 genes in Korean children with exercise-induced asthma (EIA)
Topics: Acetates; Asthma, Exercise-Induced; Bronchial Hyperreactivity; Child; Cyclopropanes; Drug Resistance; Female; Glutathione Transferase; Humans; Immunoglobulin E; Korea; Leukotriene Antagonists; Male; Membrane Proteins; Polymorphism, Genetic; Prognosis; Quinolines; Receptors, Leukotriene; Sulfides; Treatment Outcome | 2007 |
Oral monteleukast in urticaria induced by nonsteroidal anti-inflammatory drugs.
Topics: Acetates; Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Sulfides; Treatment Outcome; Urticaria | 2007 |
Gastroprotective and antioxidant effects of montelukast on indomethacin-induced gastric ulcer in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetates; Animals; Anti-Ulcer Agents; Antioxidants; Catalase; Cyclopropanes; Dose-Response Relationship, Drug; Famotidine; Gastrointestinal Agents; Glutathione Reductase; Glutathione Transferase; Histamine H2 Antagonists; Indomethacin; Intubation, Gastrointestinal; Lansoprazole; Male; Molecular Structure; Peroxidase; Quinolines; Ranitidine; Rats; Rats, Sprague-Dawley; Stomach; Stomach Ulcer; Sulfides; Superoxide Dismutase | 2007 |
Blockade of avidity and focal clustering of beta 2-integrin by cysteinyl leukotriene antagonism attenuates eosinophil adhesion.
Topics: Acetates; Arachidonate 5-Lipoxygenase; Benzoquinones; CD11b Antigen; CD18 Antigens; Cell Adhesion; Cells, Cultured; Chemokine CCL11; Cyclopropanes; Cysteine; Eosinophils; Humans; Inflammation Mediators; Interleukin-5; Leukotriene Antagonists; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Quinolines; Sulfides | 2007 |
Montelukast inhibits inflammatory responses in small airways of the Guinea-pig.
Topics: Acetates; Animals; Bronchi; Bronchoconstriction; Capillary Permeability; Cyclopropanes; Eosinophils; Guinea Pigs; Hypersensitivity; In Vitro Techniques; Leukotriene Antagonists; Male; Microcirculation; Ovalbumin; Quinolines; Receptors, Leukotriene; Sulfides | 2008 |
Differential responses to various classes of drugs in a model of allergic rhinitis in guinea pigs.
Topics: Acetates; Acute Disease; Animals; Cetirizine; Cyclopropanes; Dexamethasone; Disease Models, Animal; Guinea Pigs; Heparin; Histamine H1 Antagonists; Male; Nasal Obstruction; NG-Nitroarginine Methyl Ester; Ovalbumin; Pyrilamine; Quinolines; Rhinitis, Allergic, Seasonal; Sneezing; Sulfides | 2008 |
Prophylactic potential of montelukast against mild colitis induced by dextran sulphate sodium in rats.
Topics: Acetates; Administration, Oral; Animals; Blotting, Western; Body Weight; Bridged Bicyclo Compounds; Colitis; Colon; Cyclooxygenase 1; Cyclooxygenase 2; Cyclopropanes; Dextran Sulfate; Dinoprostone; Immunochemistry; Immunoglobulin G; Leukotriene Antagonists; Leukotriene B4; Male; Nitric Oxide Synthase Type II; Occult Blood; Quinolines; Rats; Rats, Wistar; Severity of Illness Index; Sulfides; Thromboxane B2 | 2007 |
Pediatric montelukast ingestions reported to Texas poison control centers, 2000-2005.
Topics: Acetates; Administration, Oral; Anti-Asthmatic Agents; Child, Preschool; Cyclopropanes; Dose-Response Relationship, Drug; Drug Overdose; Female; Humans; Infant; Male; Poison Control Centers; Quinolines; Retrospective Studies; Sulfides; Texas | 2007 |
Improvement in vulvar vestibulitis with montelukast.
Topics: Acetates; Adult; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Middle Aged; Quinolines; Retrospective Studies; Sulfides; Treatment Outcome; Vulvar Vestibulitis | 2007 |
Effects of KP-496, a novel dual antagonist at the cysteinyl leukotriene receptor 1 and the thromboxane A(2) receptor, on airway obstruction in guinea pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetates; Administration, Inhalation; Administration, Oral; Airway Obstruction; Animals; Anti-Asthmatic Agents; Benzoates; Benzoquinones; Bronchoconstriction; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Guinea Pigs; Heptanoic Acids; Leukotriene Antagonists; Leukotriene D4; Lung; Male; Membrane Proteins; Ovalbumin; Prostaglandin Antagonists; Quinolines; Receptors, Leukotriene; Receptors, Thromboxane A2, Prostaglandin H2; Respiratory Hypersensitivity; Sulfides; Thiazoles; Time Factors | 2008 |
Comparative study to elucidate the mechanism underlying the difference in airway hyperresponsiveness between two mouse strains.
Topics: Acetates; Administration, Inhalation; Animals; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cyclopropanes; Cysteine; Eosinophils; Immunoglobulin G; Leukotriene Antagonists; Leukotrienes; Macrophages; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Ovalbumin; Quinolines; Receptors, Leukotriene; Respiratory Hypersensitivity; Species Specificity; Sulfides | 2007 |
Suppression of plasma matrix metalloproteinase-9 following montelukast treatment in childhood asthma.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Breath Tests; Child; Cyclopropanes; Female; Histamine H1 Antagonists; Humans; Ketotifen; Leukotriene Antagonists; Male; Matrix Metalloproteinase 9; Nitric Oxide; Peak Expiratory Flow Rate; Quinolines; Severity of Illness Index; Statistics, Nonparametric; Sulfides; Tissue Inhibitor of Metalloproteinase-1 | 2007 |
[A case of chest pain variant asthma].
Topics: Acetates; Asthma; Chest Pain; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Middle Aged; Quinolines; Sulfides | 2007 |
Effects of zileuton and montelukast in mouse experimental spinal cord injury.
Topics: Acetates; Animals; Apoptosis; Arachidonate 5-Lipoxygenase; Cyclooxygenase 2; Cyclopropanes; Cysteine; Dinoprostone; Disease Models, Animal; Gene Expression Regulation; Hydroxyurea; Inflammation; Leukotrienes; Lipoxygenase Inhibitors; Male; Mice; Neutrophil Infiltration; Quinolines; Recovery of Function; Spinal Cord Injuries; Sulfides; Tumor Necrosis Factor-alpha | 2008 |
Emerging therapies for respiratory diseases.
Topics: Acetates; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Albuterol; Budesonide; Budesonide, Formoterol Fumarate Drug Combination; Cyclopropanes; Drug Combinations; Drug Therapy; Ethanolamines; Humans; Leukotriene Antagonists; Molecular Structure; Quinolines; Respiratory Tract Diseases; Sulfides | 2007 |
Does leukotriene affect intracellular glutathione redox state in cultured human airway epithelial cells?
Topics: Acetates; Cells, Cultured; Cyclopropanes; Dose-Response Relationship, Drug; Glutathione; Glutathione Disulfide; Humans; Leukotriene C4; Leukotrienes; Oxidation-Reduction; Quinolines; Respiratory Mucosa; Sulfides | 2008 |
[Biased about the treatment of asthma in children].
Topics: Acetates; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Child; Cyclopropanes; Fluticasone; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2007 |
[Case of chest pain variant asthma].
Topics: Acetates; Adult; Androstadienes; Asthma; Chest Pain; Cyclopropanes; Drug Therapy, Combination; Fluticasone; Humans; Leukotriene Antagonists; Male; Membrane Proteins; Prednisolone; Procaterol; Quinolines; Receptors, Leukotriene; Sulfides | 2008 |
In vitro metabolism of 2-[6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl] acetic acid (licofelone, ML3000), an inhibitor of cyclooxygenase-1 and -2 and 5-lipoxygenase.
Topics: Acetates; Animals; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cyclopropanes; Cytochrome P-450 Enzyme System; Glucuronosyltransferase; Hepatocytes; Humans; Lipoxygenase Inhibitors; Macaca fascicularis; Mice; Mice, Inbred Strains; Microsomes; Paclitaxel; Pyrroles; Quinolines; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sulfides | 2008 |
The leucotriene receptor antagonist montelukast and the risk of Churg-Strauss syndrome: a case-crossover study.
Topics: Acetates; Acute Disease; Anti-Asthmatic Agents; Antibodies, Antineutrophil Cytoplasmic; Asthma; Case-Control Studies; Churg-Strauss Syndrome; Cross-Over Studies; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Sulfides | 2008 |
Cysteinyl leukotriene-1 receptor activation in a human bronchial epithelial cell line leads to signal transducer and activator of transcription 1-mediated eosinophil adhesion.
Topics: Acetates; Bronchi; Cell Adhesion; Cell Line; Cells, Cultured; Cyclopropanes; Eosinophils; Epithelial Cells; Humans; Indoles; Intercellular Adhesion Molecule-1; Interferon-gamma; Leukotriene Antagonists; Leukotriene D4; Maleimides; Membrane Proteins; Mitogen-Activated Protein Kinases; Quinolines; Receptors, Leukotriene; STAT1 Transcription Factor; Sulfides | 2008 |
Montelukast inhibits tumour necrosis factor-alpha-mediated interleukin-8 expression through inhibition of nuclear factor-kappaB p65-associated histone acetyltransferase activity.
Topics: Acetates; Cyclopropanes; Histone Acetyltransferases; Humans; Interleukin-8; Leukotriene Antagonists; Macrophages; NF-kappa B; Quinolines; Signal Transduction; Sulfides; Tumor Necrosis Factor-alpha; U937 Cells | 2008 |
Extrapolating evidence beyond age groups.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Age Factors; Anti-Asthmatic Agents; Asthma; Budesonide; Child; Child, Preschool; Cyclopropanes; Female; Humans; Infant; Leukotriene Antagonists; Male; Quinolines; Randomized Controlled Trials as Topic; Research Design; Sulfides; Treatment Outcome | 2008 |
Montelukast inhibition of resting and GM-CSF-stimulated eosinophil adhesion to VCAM-1 under flow conditions appears independent of cysLT(1)R antagonism.
Topics: Acetates; Cell Adhesion; Cyclopropanes; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukotriene Antagonists; Membrane Proteins; Quinolines; Receptors, Leukotriene; Sulfides; Vascular Cell Adhesion Molecule-1 | 2008 |
Determination of montelukast sodium by capillary electrophoresis.
Topics: Acetates; Chromatography, High Pressure Liquid; Cyclodextrins; Cyclopropanes; Electrophoresis, Capillary; Isomerism; Molecular Structure; Quinolines; Sulfides | 2008 |
Individual case safety reports in children in commonly used drug groups - signal detection.
Topics: Acetates; Adolescent; Adverse Drug Reaction Reporting Systems; Child; Child, Preschool; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Humans; Leukotriene Antagonists; Pediatrics; Quinolines; Sulfides; Sweden | 2008 |
Leukotriene D4 receptor antagonist montelukast alleviates water avoidance stress-induced degeneration of the gastrointestinal mucosa.
Topics: Acetates; Animals; Cyclopropanes; Gastric Mucosa; Glutathione; Intestinal Mucosa; Leukotriene Antagonists; Malondialdehyde; Quinolines; Rats; Rats, Inbred Strains; Receptors, Leukotriene; Stress, Physiological; Sulfides | 2008 |
[Churg-Strauss syndrome in a patient with asthma treated with montelukast].
Topics: Acetates; Aged; Anti-Asthmatic Agents; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Eosinophilia; Female; Humans; Quinolines; Sulfides | 2008 |
Determinants of cytochrome P450 2C8 substrate binding: structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid.
Topics: Acetates; Alitretinoin; Aryl Hydrocarbon Hydroxylases; Binding Sites; Chromans; Crystallography, X-Ray; Cyclopropanes; Cytochrome P-450 CYP2C8; Felodipine; Heme; Humans; Iron; Leukotriene Antagonists; Ligands; Molecular Conformation; Protein Binding; Quinolines; Substrate Specificity; Sulfides; Thiazolidinediones; Tretinoin; Troglitazone | 2008 |
[Asthma patients with allergic rhinitis, To treat airways as a whole!].
Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Budesonide; Cyclopropanes; Drug Therapy, Combination; Germany; Glucocorticoids; Humans; Leukotriene Antagonists; Multicenter Studies as Topic; Quinolines; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sulfides | 2005 |
[Therapy of bronchial asthma. To fight inflammation].
Topics: Acetates; Adolescent; Adult; Aged; Androstadienes; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchodilator Agents; Budesonide; Cyclopropanes; Drug Therapy, Combination; Fluticasone; Glucocorticoids; Humans; Leukotriene Antagonists; Middle Aged; Multicenter Studies as Topic; Quinolines; Randomized Controlled Trials as Topic; Sulfides; Time Factors | 2005 |
Urticaria triggered by antiallergy treatment.
Topics: Acetates; Anti-Asthmatic Agents; Chronic Disease; Cyclopropanes; Female; Humans; Immunologic Tests; Middle Aged; Quinolines; Sulfides; Urticaria | 2008 |
A simple bioanalytical assay for determination of montelukast in human plasma: application to a pharmacokinetic study.
Topics: Acetates; Anti-Asthmatic Agents; Calibration; Chromatography, High Pressure Liquid; Cyclopropanes; Humans; Leukotriene Antagonists; Male; Quinolines; Reproducibility of Results; Sulfides | 2008 |
Gender differences in the effectiveness of asthma treatment.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Female; Humans; Lung; Male; Quinolines; Sex Characteristics; Sulfides | 2008 |
[Importance of leukotriene antagonists in asthma therapy raised].
Topics: Acetates; Adolescent; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Algorithms; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Clinical Trials as Topic; Cohort Studies; Cyclopropanes; Drug Therapy, Combination; Humans; Leukotriene Antagonists; Practice Guidelines as Topic; Quinolines; Respiratory Therapy; Smoking; Sulfides; Time Factors | 2008 |
Magnesium and other bivalent cations influence upon sodium montelukast effect in experimental-induced thermoalgesia.
Topics: Acetates; Animals; Cations; Copper; Cyclopropanes; Hot Temperature; Hyperalgesia; Injections, Intraperitoneal; Leukotriene Antagonists; Magnesium; Male; Quinolines; Rats; Rats, Wistar; Sulfides; Zinc | 2008 |
Dynamic dissolution testing to establish in vitro/in vivo correlations for montelukast sodium, a poorly soluble drug.
Topics: Acetates; Computer Simulation; Cyclopropanes; Humans; Particle Size; Quinolines; Solubility; Sulfides | 2008 |
Clarithromycin, montelukast, and pentoxifylline combination treatment ameliorates experimental neonatal hyperoxic lung injury.
Topics: Acetates; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Bronchopulmonary Dysplasia; Clarithromycin; Cyclopropanes; Disease Models, Animal; Drug Therapy, Combination; Humans; Infant, Newborn; Leukotriene Antagonists; Oxygen Inhalation Therapy; Pentoxifylline; Quinolines; Rats; Sulfides | 2008 |
The leukotriene d4 receptor antagonist, montelukast, inhibits mast cell degranulation in the dermis induced by water avoidance stress.
Topics: Acetates; Animals; Cell Degranulation; Cyclopropanes; Dermis; Female; Immunohistochemistry; Injections, Intraperitoneal; Leukotriene Antagonists; Mast Cells; Quinolines; Rats; Rats, Wistar; Stress, Physiological; Sulfides; Tolonium Chloride; Tryptases | 2009 |
Cysteinyl leucotriene receptor type 1 mediates contraction in human and guinea-pig oesophagus.
Topics: Acetates; Animals; Atropine; Capsaicin; Carbachol; Cholinergic Agonists; Cyclopropanes; Esophagus; Guinea Pigs; Humans; Indoles; Leukotriene Antagonists; Leukotrienes; Male; Muscarinic Antagonists; Muscle Contraction; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Sensory System Agents; Sodium Channel Blockers; SRS-A; Sulfides; Sulfonamides; Tetrodotoxin; Tosyl Compounds | 2008 |
Effect of montelukast and MK-886 on hepatic ischemia-reperfusion injury in rats.
Topics: Acetates; Animals; Cyclopropanes; Disease Models, Animal; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Liver Diseases; Male; Quinolines; Rats; Rats, Wistar; Reperfusion Injury; Sulfides | 2009 |
[Churg-Strauss syndrome in a patient with asthma treated with montelukast].
Topics: Acetates; Anti-Asthmatic Agents; Churg-Strauss Syndrome; Cyclopropanes; Evidence-Based Medicine; Humans; Quinolines; Sulfides | 2008 |
Joint statement on FDA investigation of Singulair from the ACAAI and AAAAI.
Topics: Academies and Institutes; Acetates; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Suicide; Sulfides; United States; United States Food and Drug Administration | 2008 |
Identification, synthesis, isolation and spectral characterization of potential impurities of montelukast sodium.
Topics: Acetates; Chromatography, High Pressure Liquid; Cyclopropanes; Drug Contamination; Leukotriene Antagonists; Mass Spectrometry; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Quinolines; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Sulfides | 2008 |
Confirmation that cytochrome P450 2C8 (CYP2C8) plays a minor role in (S)-(+)- and (R)-(-)-ibuprofen hydroxylation in vitro.
Topics: Acetates; Antibodies, Monoclonal; Aryl Hydrocarbon Hydroxylases; Catalysis; Cyclopropanes; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diclofenac; Enzyme Inhibitors; Genotype; Humans; Hydroxylation; Ibuprofen; Ketoconazole; Kinetics; Mephenytoin; Microsomes, Liver; Quinolines; Recombinant Proteins; Stereoisomerism; Sulfaphenazole; Sulfides; Tandem Mass Spectrometry | 2008 |
Influence of leukotriene inhibitor montelukast on wound contraction and cutaneous healing process in rats.
Topics: Acetates; Animals; Collagen; Cyclopropanes; Dermatologic Surgical Procedures; Disease Models, Animal; Leukotriene Antagonists; Male; Probability; Quinolines; Random Allocation; Rats; Rats, Wistar; Reference Values; Sensitivity and Specificity; Skin; Statistics, Nonparametric; Sulfides; Wound Healing | 2009 |
Pharmacological modulation of leukotriene D(4) attenuates the development of opioid dependence in a mouse model of naloxone-induced opioid withdrawal syndrome.
Topics: Acetates; Animals; Cyclopropanes; Female; Leukotriene Antagonists; Leukotriene D4; Male; Mice; Motor Activity; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Pain Measurement; Pain Threshold; Quinolines; Signal Transduction; Substance Withdrawal Syndrome; Sulfides; Tetrahydroisoquinolines | 2008 |
The effect of montelukast on atherogenesis in apoE/LDLR-double knockout mice.
Topics: Acetates; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cholesterol; Cyclopropanes; Female; Leukotriene Antagonists; Lipids; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Quinolines; Receptors, LDL; Sulfides; Triglycerides | 2008 |
Intercellular Ca2+ wave propagation involving positive feedback between CRAC channels and cysteinyl leukotrienes.
Topics: Acetates; Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Cells, Cultured; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Leukotriene C4; Mast Cells; Paracrine Communication; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Leukotriene; Sulfides | 2009 |
Histological appearances of putative montelukast related Churg-Strauss syndrome.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Biopsy; Churg-Strauss Syndrome; Cyclopropanes; Humans; Leukotriene Antagonists; Lung; Male; Quinolines; Sulfides | 2008 |
Emergency pretreatment for contrast allergy before direct percutaneous coronary intervention for ST-elevation myocardial infarction.
Topics: Acetates; Angioplasty, Balloon, Coronary; Anti-Inflammatory Agents; Antiemetics; Cimetidine; Contrast Media; Cyclopropanes; Drug Hypersensitivity; Drug Therapy, Combination; Emergency Medical Services; Heart Conduction System; Histamine H2 Antagonists; Humans; Leukotriene Antagonists; Methylprednisolone; Myocardial Infarction; Prochlorperazine; Quinolines; Sulfides; Time Factors | 2008 |
The protective effect of montelukast sodium on carbon tetrachloride induced hepatopathy in rat.
Topics: Acetates; Alanine Transaminase; Animals; Bilirubin; Carbon Tetrachloride; Catalase; Chemical and Drug Induced Liver Injury; Cyclopropanes; Liver; Liver Diseases; Male; Malondialdehyde; Quinolines; Rats; Rats, Wistar; Sulfides; Superoxide Dismutase | 2009 |
Montelukast inhibits neutrophil pro-inflammatory activity by a cyclic AMP-dependent mechanism.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acetates; Calcium; Chemotactic Factors; Cyclic AMP; Cyclopropanes; Dose-Response Relationship, Drug; Fluorescent Dyes; Fura-2; Humans; In Vitro Techniques; Leukotriene Antagonists; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Pancreatic Elastase; Quinolines; Reactive Oxygen Species; Receptors, Leukotriene; Sulfides | 2009 |
[The relevance of leukotriene C(4) synthase gene A (-444) C polymorphism to clinical responsiveness to montelukast in patients with asthma].
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asian People; Asthma; Case-Control Studies; Cyclopropanes; Female; Gene Frequency; Genotype; Glutathione Transferase; Humans; Leukotriene Antagonists; Male; Middle Aged; Polymorphism, Single Nucleotide; Quinolines; Sulfides; Treatment Outcome | 2008 |
Asthma in the preschool child: still a rose by any other name?
Topics: Acetates; Administration, Inhalation; Albuterol; Bronchodilator Agents; Budesonide; Child, Preschool; Cyclopropanes; Double-Blind Method; Female; Glucocorticoids; Humans; Infant; Leukotriene Antagonists; Male; Quinolines; Respiratory Sounds; Respiratory Tract Diseases; Sulfides | 2008 |
Anti-atherogenic effects of montelukast associated with reduced MCP-1 expression in a rabbit carotid balloon injury model.
Topics: Acetates; Animals; Atherosclerosis; Atorvastatin; Carotid Arteries; Catheterization; Chemokine CCL2; Cyclopropanes; Diet, Atherogenic; Disease Progression; Heptanoic Acids; Immunohistochemistry; Leukotriene Antagonists; Lipids; Male; Pyrroles; Quinolines; Rabbits; Random Allocation; Sulfides | 2009 |
Leukotriene pathways and in vitro adenotonsillar cell proliferation in children with obstructive sleep apnea.
Topics: Acetates; Adenoids; Apoptosis; Cell Proliferation; Cells, Cultured; Child; Child, Preschool; Cyclopropanes; Dose-Response Relationship, Drug; Humans; Hydroxyurea; Immunohistochemistry; Interleukins; Leukotriene Antagonists; Leukotriene D4; Palatine Tonsil; Polysomnography; Quinolines; Sleep Apnea, Obstructive; SRS-A; Sulfides | 2009 |
Predicting an asthma exacerbation in children 2 to 5 years of age.
Topics: Acetates; Adrenergic beta-Agonists; Anti-Asthmatic Agents; Asthma; Child, Preschool; Cough; Cyclopropanes; Drug Administration Schedule; Humans; Multivariate Analysis; Prognosis; Quinolines; Remission, Spontaneous; Respiratory Sounds; Severity of Illness Index; Sulfides | 2008 |
Phenotypic predictors of long-term response to inhaled corticosteroid and leukotriene modifier therapies in pediatric asthma.
Topics: Acetates; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Androstadienes; Anti-Allergic Agents; Asthma; Child; Cyclopropanes; Exhalation; Female; Fluticasone; Humans; Leukotriene Antagonists; Male; Nitric Oxide; Prognosis; Quinolines; Randomized Controlled Trials as Topic; Sulfides; Treatment Outcome | 2009 |
[Churg-Strauss syndrome associated with montelukast].
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Eosinophilia; Eosinophils; Female; Humans; Middle Aged; Quinolines; Sulfides | 2008 |
Effects of the immunomodulatory agent Cordyceps militaris on airway inflammation in a mouse asthma model.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Cordyceps; Cyclopropanes; Disease Models, Animal; Female; Immunologic Factors; Mice; Mice, Inbred BALB C; Prednisolone; Quinolines; Random Allocation; Sulfides | 2008 |
Absorption of montelukast is transporter mediated: a common variant of OATP2B1 is associated with reduced plasma concentrations and poor response.
Topics: Absorption; Acetates; Adult; Caco-2 Cells; Cyclopropanes; Genetic Variation; Genotype; Humans; Organic Anion Transporters; Phenotype; Quinolines; Sulfides | 2009 |
Rate of suicide in patients taking montelukast.
Topics: Acetates; Anti-Asthmatic Agents; Cohort Studies; Cyclopropanes; Databases, Factual; Female; Humans; Middle Aged; Quinolines; Risk; Suicide; Sulfides; United Kingdom | 2009 |
Leukotrienes C4 and D4 sensitize human neutrophils for hyperreactivity to chemoattractants.
Topics: Acetates; Adult; Chemotactic Factors; Cyclopropanes; Fluorescent Dyes; Fura-2; Humans; Inflammation; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Matrix Metalloproteinase 8; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Quinolines; Sulfides; Superoxides | 2009 |
Cough reflex sensitivity is increased in the guinea pig model of allergic rhinitis.
Topics: Acetates; Allergens; Animals; Anti-Asthmatic Agents; Citric Acid; Cough; Cyclopropanes; Guinea Pigs; Inflammation; Leukotriene Antagonists; Male; Nasal Mucosa; Ovalbumin; Quinolines; Reflex; Rhinitis, Allergic, Seasonal; Sulfides | 2008 |
[Effects of montelukast and BCG-PSN on the expression of STAT5b mRNA and IL-4 mRNA in blood mononuclearcells of rats with asthma].
Topics: Acetates; Animals; Asthma; BCG Vaccine; Cyclopropanes; Interferon-gamma; Interleukin-4; Leukocytes, Mononuclear; Male; Quinolines; Rats; Rats, Sprague-Dawley; RNA, Messenger; STAT5 Transcription Factor; Sulfides | 2009 |
Leukotriene D4 stimulates the migration but not proliferation of endothelial cells mediated by the cysteinyl leukotriene cyslt(1) receptor via the extracellular signal-regulated kinase pathway.
Topics: Acetates; Butadienes; Cell Line; Cell Movement; Cell Proliferation; Cyclopropanes; Endothelial Cells; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Humans; Leukotriene Antagonists; Leukotriene D4; Nitriles; Quinolines; Receptors, Leukotriene; SRS-A; Sulfides | 2009 |
15-lipoxygenase metabolites play an important role in the development of a T-helper type 1 allergic inflammation induced by double-stranded RNA.
Topics: Acetates; Allergens; Alum Compounds; Animals; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Cyclopropanes; Disease Models, Animal; Fatty Alcohols; Fluorenes; Glycols; Hypersensitivity; Inflammation; Leukotriene Antagonists; Lipoxygenase Inhibitors; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Ovalbumin; Poly I-C; Quinolines; Receptors, Leukotriene; Receptors, Leukotriene B4; RNA, Double-Stranded; Sulfides; Th1 Cells; Th2 Cells | 2009 |
Cysteinyl leukotrienes enhance the degranulation of bone marrow-derived mast cells through the autocrine mechanism.
Topics: Acetates; Animals; Autocrine Communication; Bone Marrow Cells; Cell Degranulation; Chromatography, Liquid; Cyclopropanes; Mast Cells; Mice; Quinolines; SRS-A; Sulfides; Tandem Mass Spectrometry | 2009 |
Singulair-induced anaphylaxis?
Topics: Acetates; Anaphylaxis; Anti-Asthmatic Agents; Asthma; Child, Preschool; Conjunctivitis, Allergic; Cyclopropanes; Dermatitis, Atopic; Humans; Infant; Leukotriene Antagonists; Male; Prognosis; Quinolines; Respiratory Hypersensitivity; Sulfides | 2009 |
Urinary cysteinyl leukotriene E4 significantly increases during pain in children and adults with sickle cell disease.
Topics: Acetates; Adolescent; Adult; Anemia, Sickle Cell; Anti-Asthmatic Agents; Asthma; beta-Thalassemia; Biomarkers; Child; Cohort Studies; Cyclopropanes; Female; Fetal Hemoglobin; Hemoglobin C Disease; Heterozygote; Hospitalization; Humans; Ischemia; Leukotriene Antagonists; Leukotriene E4; Male; Pain; Quinolines; Retrospective Studies; Sickle Cell Trait; Sulfides; Young Adult | 2009 |
Quantification of montelukast, a selective cysteinyl leukotriene receptor (CysLT1) antagonist in human plasma by liquid chromatography-mass spectrometry: validation and its application to a human pharmacokinetic study.
Topics: Acetates; Chromatography, Liquid; Cyclopropanes; Humans; Leukotriene Antagonists; Male; Quinolines; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Sulfides; Tandem Mass Spectrometry; Time Factors | 2009 |
Rates of asthma attacks in patients with previously inadequately controlled mild asthma treated in clinical practice with combination drug therapy: an exploratory post-hoc analysis.
Topics: Acetates; Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Adult; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Drug Therapy, Combination; Europe; Female; Follow-Up Studies; Glucocorticoids; Humans; Incidence; Male; Middle Aged; Quinolines; Recurrence; Retrospective Studies; Sulfides; Time Factors; Young Adult | 2009 |
Asthma drugs counter-regulate interleukin-8 release stimulated by sodium sulfite in an A549 cell line.
Topics: Acetates; Air Pollutants; Albuterol; Androstadienes; Anti-Asthmatic Agents; Cell Line; Cell Survival; Cyclopropanes; Dose-Response Relationship, Drug; Epithelial Cells; Fluticasone; Humans; Inflammation; Interleukin-8; Lung; Quinolines; Salmeterol Xinafoate; Signal Transduction; Sulfides; Sulfites | 2009 |
Montelukast-associated Churg-Strauss vasculitis: another associated report.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Churg-Strauss Syndrome; Cough; Cyclopropanes; Eosinophils; Female; Humans; Quinolines; Skin; Sulfides | 2009 |
Cysteinyl-leukotriene receptor antagonist montelukast decreases blood-brain barrier permeability but does not prevent oedema formation in traumatic brain injury.
Topics: Acetates; Animals; Blood-Brain Barrier; Brain Edema; Brain Injuries; Cyclopropanes; Immunologic Factors; Leukotriene Antagonists; Neuroprotective Agents; Oxidative Stress; Permeability; Quinolines; Rats; Rats, Sprague-Dawley; Sulfides | 2009 |
The anti-inflammatory effects of inhaled corticosteroids versus anti-leukotrienes on the lymphocyte P-glycoprotein (PGP) expression in asthmatic children.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adolescent; Adrenal Cortex Hormones; Asthma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Budesonide; Case-Control Studies; Child; Child, Preschool; Cyclopropanes; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Follow-Up Studies; Humans; Inflammation Mediators; Leukotriene Antagonists; Male; Nebulizers and Vaporizers; Probability; Quinolines; Reference Values; Sensitivity and Specificity; Severity of Illness Index; Sulfides; T-Lymphocytes; Treatment Outcome | 2009 |
A prostaglandin D2 receptor antagonist modifies experimental asthma in sheep.
Topics: Acetates; Allergens; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Cyclic AMP; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Prostaglandin D2; Quinolines; Receptors, Immunologic; Receptors, Prostaglandin; Sulfides; Thiophenes; Time Factors | 2009 |
[Churg-Strauss syndrome: diagnostic and therapeutic challenge - a case report].
Topics: Acetates; Adult; Churg-Strauss Syndrome; Cyclopropanes; Humans; Leukotriene Antagonists; Male; Pericarditis; Pneumonia; Quinolines; Sulfides | 2009 |
Protective potential of montelukast against hepatic ischemia/reperfusion injury in rats.
Topics: Acetates; Animals; Cyclopropanes; Cytokines; Glutathione; Leukotriene Antagonists; Liver; Liver Diseases; Liver Function Tests; Male; Malondialdehyde; Peroxidase; Quinolines; Rats; Rats, Wistar; Reperfusion Injury; Sulfides | 2010 |
[Non-interventional study with remarkable results. Improved asthma control and quality of life with montelukast].
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Delayed-Action Preparations; Drug Therapy, Combination; Humans; Quinolines; Sulfides | 2009 |
Enhanced fracture repair by leukotriene antagonism is characterized by increased chondrocyte proliferation and early bone formation: a novel role of the cysteinyl LT-1 receptor.
Topics: Acetates; Animals; Arachidonate 5-Lipoxygenase; Cell Proliferation; Chondrocytes; Cyclopropanes; Fracture Healing; Fractures, Bone; Gene Expression Regulation; Hydroxyurea; Hypertrophy; Leukotriene Antagonists; Leukotriene B4; Mice; Models, Biological; Osteogenesis; Quinolines; Radiography; Receptors, Leukotriene; Sulfides | 2009 |
Montelukast and psychiatric disorders in children.
Topics: Acetates; Adolescent; Adverse Drug Reaction Reporting Systems; Anti-Asthmatic Agents; Child; Child, Preschool; Cyclopropanes; Female; Humans; Infant; Male; Mental Disorders; Quinolines; Sulfides; Sweden | 2009 |
Sleep-related breathing in children with mucopolysaccharidosis.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Child; Child, Preschool; Cyclopropanes; Female; Humans; Infant; Male; Mucopolysaccharidoses; Polysomnography; Positive-Pressure Respiration; Prevalence; Quinolines; Respiration; Retrospective Studies; Sleep; Sleep Apnea Syndromes; Sulfides; Tonsillectomy; Treatment Outcome | 2009 |
[Effects of leukotriene receptor antagonists on vascular endothelial growth factor and its receptors in a sensitized rat model].
Topics: Acetates; Airway Remodeling; Animals; Asthma; Cyclopropanes; Leukotriene Antagonists; Leukotriene D4; Male; Neovascularization, Pathologic; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Vascular Endothelial Growth Factor; Sulfides; Vascular Endothelial Growth Factor A | 2009 |
Montelukast protects axial pattern rat skin flaps against ischemia/reperfusion injury.
Topics: Acetates; Animals; Cell Movement; Cyclopropanes; Glutathione; Graft Survival; Injections, Intraperitoneal; Leukotriene Antagonists; Male; Malondialdehyde; Models, Animal; Neutrophils; Peroxidase; Quinolines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Skin Transplantation; Sulfides; Surgical Flaps; Treatment Outcome | 2009 |
Role of sphingosine-1-phosphate (S1P) and the S1P(2) receptor in allergen-induced, mast cell-dependent contraction of rat lung parenchymal strips.
Topics: Acetates; Adenosine; Allergens; Animals; Bronchoconstriction; Cyclopropanes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Injections, Subcutaneous; Leukotriene Antagonists; Lung; Lysophospholipids; Male; Mast Cells; Methysergide; Ovalbumin; Phosphotransferases (Alcohol Group Acceptor); Pyrazoles; Pyridines; Quinolines; Rats; Rats, Inbred BN; Receptors, Lysosphingolipid; Serotonin; Serotonin Antagonists; Signal Transduction; Sphingosine; Sulfides; Thiazoles | 2009 |
Churg-Strauss syndrome associated with montelukast therapy.
Topics: Acetates; Adult; Aged, 80 and over; Anti-Asthmatic Agents; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Pulmonary Eosinophilia; Quinolines; Sulfides | 2009 |
[Eosinophilic esophagitis: report of three cases].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetates; Adolescent; Child; Cyclopropanes; Eosinophilia; Esophagitis; Esophagoscopy; Humans; Lansoprazole; Male; Omeprazole; Quinolines; Sulfides | 2009 |
Inhaled montelukast inhibits cysteinyl-leukotriene-induced bronchoconstriction in ovalbumin-sensitized guinea-pigs: the potential as a new asthma medication.
Topics: Acetates; Administration, Inhalation; Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Cyclopropanes; Cysteine; Disease Models, Animal; Guinea Pigs; Immunologic Factors; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotrienes; Lung; Male; Ovalbumin; Quinolines; Sulfides | 2009 |
Montelukast use during pregnancy: a multicentre, prospective, comparative study of infant outcomes.
Topics: Acetates; Adult; Asthma; Cyclopropanes; Female; Humans; Infant, Newborn; Leukotriene Antagonists; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Quinolines; Sulfides | 2009 |
The placebo effect in asthma: Far more complex than simply "I shall please".
Topics: Acetates; Asthma; Central Nervous System; Cyclopropanes; Humans; Leukotriene Antagonists; Placebo Effect; Quinolines; Randomized Controlled Trials as Topic; Sulfides | 2009 |
Predictors of asthma control in everyday clinical practice in Switzerland.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Cohort Studies; Cyclopropanes; Female; Humans; Male; Middle Aged; Quinolines; Sulfides; Switzerland | 2009 |
Churg-Strauss syndrome secondary to antileucotriene therapy in a patient not receiving oral corticosteroids.
Topics: Acetates; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Drug Eruptions; Female; Glucocorticoids; Humans; Leukotriene Antagonists; Quinolines; Sulfides; Vasculitis, Leukocytoclastic, Cutaneous; Young Adult | 2009 |
Possible montelukast-induced angioedema.
Topics: Acetates; Angioedema; Cyclopropanes; Female; Humans; Hypersensitivity; Leukotriene Antagonists; Middle Aged; Quinolines; Sulfides | 2009 |
Reports of suicidality in clinical trials of montelukast.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Mental Disorders; Quinolines; Retrospective Studies; Risk Assessment; Self-Injurious Behavior; Suicide; Sulfides | 2009 |
Assessing risk: Data from montelukast clinical trials.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Leukotriene Antagonists; Mental Disorders; Quinolines; Risk Assessment; Suicide; Sulfides | 2009 |
Analysis of behavior-related adverse experiences in clinical trials of montelukast.
Topics: Acetates; Adolescent; Adult; Aged; Anti-Asthmatic Agents; Asthma; Behavioral Symptoms; Child; Child, Preschool; Clinical Trials as Topic; Cyclopropanes; Female; Humans; Male; Mental Disorders; Middle Aged; Quinolines; Retrospective Studies; Sulfides; Young Adult | 2009 |
Targeting Ca2+ release-activated Ca2+ channel channels and leukotriene receptors provides a novel combination strategy for treating nasal polyposis.
Topics: Acetates; Arachidonate 5-Lipoxygenase; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cyclopropanes; Humans; Hydroxyurea; Leukotriene Antagonists; Leukotriene C4; Mast Cells; Nasal Polyps; Quinolines; Receptors, Leukotriene; Sulfides; Thapsigargin | 2009 |
Adherence to combined montelukast and fluticasone treatment in economically disadvantaged african american youth with asthma.
Topics: Acetates; Adolescent; Albuterol; Ambulatory Care; Androstadienes; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Black or African American; Caregivers; Child; Child, Preschool; Cyclopropanes; Emergency Medical Services; Female; Fluticasone; Follow-Up Studies; Hospitalization; Humans; Male; Medication Adherence; Poverty; Quinolines; Sulfides; Time Factors; Treatment Outcome | 2009 |
Treatment of allergic rhinitis in infants and children: efficacy and safety of second-generation antihistamines and the leukotriene receptor antagonist montelukast.
Topics: Acetates; Administration, Oral; Adult; Anti-Allergic Agents; Anti-Asthmatic Agents; Astemizole; Cetirizine; Child; Cyclopropanes; Drug Administration Schedule; Drug Interactions; Histamine H1 Antagonists, Non-Sedating; Humans; Ketotifen; Leukotriene Antagonists; Loratadine; Piperazines; Quinolines; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Safety; Sulfides; Tablets; Terfenadine; Treatment Outcome | 2009 |
Montelukast is a potent and durable inhibitor of multidrug resistance protein 2-mediated efflux of taxol and saquinavir.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Antineoplastic Agents, Phytogenic; Biological Transport; Cell Line; Chemotherapy, Adjuvant; Cyclopropanes; Dogs; Drug Resistance, Neoplasm; Drug Resistance, Viral; Fluoresceins; HIV Infections; HIV Protease Inhibitors; Indoles; Leukotriene Antagonists; Multidrug Resistance-Associated Proteins; Neoplasms; Paclitaxel; Phenylcarbamates; Propionates; Quinolines; Saquinavir; Sulfides; Sulfonamides; Time Factors; Tosyl Compounds | 2009 |
Effect of ciclesonide on bronchial asthma in athletes.
Topics: Acetates; Adolescent; Asthma; Athletes; Breath Tests; Cyclopropanes; Female; Forced Expiratory Volume; Humans; Male; Maximal Midexpiratory Flow Rate; Nitric Oxide; Pregnenediones; Quinolines; Retrospective Studies; Sulfides; Treatment Outcome; Vital Capacity; Young Adult | 2009 |
Montelukast inhibits matrix metalloproteinases expression in atherosclerotic rabbits.
Topics: Acetates; Animals; Atherosclerosis; Atorvastatin; Cyclopropanes; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukotriene Antagonists; Lipids; Macrophages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocytes, Smooth Muscle; Pyrroles; Quinolines; Rabbits; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; Sulfides | 2009 |
Add-on montelukast in inadequately controlled asthma patients in a 6-month open-label study: the MONtelukast In Chronic Asthma (MONICA) study.
Topics: Acetates; Adrenergic beta-Agonists; Adult; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Prospective Studies; Quality of Life; Quinolines; Sulfides; Surveys and Questionnaires; Treatment Outcome; Young Adult | 2010 |
Oral ulcerations in a patient with severe asthma.
Topics: Acetates; Adrenal Cortex Hormones; Aged; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Diagnosis, Differential; Female; Histoplasmosis; Humans; Immunosuppression Therapy; Leukotriene Antagonists; Mouth Mucosa; Mouth Neoplasms; Oral Ulcer; Prednisone; Quinolines; Severity of Illness Index; Stomatitis, Aphthous; Sulfides; Tongue Diseases | 2010 |
Corticosteroids and montelukast: effects on airway epithelial and human umbilical vein endothelial cells.
Topics: Acetates; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Apoptosis; Asthma; Cell Line; Cyclopropanes; Cytokines; Desmosomes; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Leukotriene Antagonists; Necrosis; Quinolines; Respiratory Mucosa; Sulfides; Umbilical Veins | 2010 |
Concentration-dependent noncysteinyl leukotriene type 1 receptor-mediated inhibitory activity of leukotriene receptor antagonists.
Topics: Acetates; Calcium; Calcium Signaling; Cell Line; Cell Migration Inhibition; Cells, Cultured; Chemotaxis, Leukocyte; Cyclopropanes; Humans; Indoles; Inflammation Mediators; Intracellular Fluid; Leukotriene Antagonists; Models, Immunological; Monocytes; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds; Uridine Diphosphate | 2010 |
Protective effect of montelukast on paraquat-induced lung toxicity in rats.
Topics: Acetates; Animals; Cyclopropanes; DNA Fragmentation; Glutathione; L-Lactate Dehydrogenase; Lung; Male; Malondialdehyde; Paraquat; Peroxidase; Quinolines; Rats; Rats, Wistar; Sulfides; Tumor Necrosis Factor-alpha | 2009 |
FDC of montelukast with levocetirizine: focus on bilayer technology.
Topics: Acetates; Cetirizine; Cyclopropanes; Drug Combinations; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Quality of Life; Quinolines; Rhinitis, Allergic, Perennial; Sulfides; Tablets; Treatment Outcome | 2009 |
The efficacy of montelukast monotherapy in moderate persistent asthmatic children.
Topics: Acetates; Adolescent; Asthma; Budesonide; Child; Cyclopropanes; Drug Therapy, Combination; Humans; Leukotriene Antagonists; Prospective Studies; Quinolines; Sulfides | 2009 |
Paradoxical exacerbation of chronic urticaria by H1-antihistamines and montelukast.
Topics: Acetates; Adult; Azathioprine; Chronic Disease; Cyclopropanes; Cyclosporine; Histamine H1 Antagonists; Humans; Male; Quinolines; Sulfides; Urticaria | 2009 |
Recent-onset bronchial asthma as a manifestation of systemic mastocytosis.
Topics: Abdominal Pain; Acetates; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Budesonide; Capillary Permeability; Cough; Cyclopropanes; Diarrhea; Dyspnea; Female; Humans; Lung; Mast Cells; Mastocytosis, Systemic; Middle Aged; Nedocromil; Quinolines; Sulfides | 2009 |
Antisecretory, antioxidative and antiapoptotic effects of montelukast on pyloric ligation and water immersion stress induced peptic ulcer in rat.
Topics: Acetates; Animals; Cyclopropanes; Disease Models, Animal; DNA Fragmentation; Gastric Mucosa; Glutathione; Leukotriene Antagonists; Male; Peptic Ulcer; Peroxidase; Quinolines; Rats; Rats, Wistar; Stomach; Stress, Psychological; Sulfides; Thiobarbituric Acid Reactive Substances | 2010 |
Cysteinyl leukotrienes acting via granule membrane-expressed receptors elicit secretion from within cell-free human eosinophil granules.
Topics: Acetates; Blotting, Western; Cell Separation; Cell-Free System; Cyclopropanes; Cysteine; Eosinophil Cationic Protein; Eosinophils; Flow Cytometry; Humans; Leukotriene Antagonists; Leukotrienes; Quinolines; Receptors, Leukotriene; Secretory Vesicles; Sulfides | 2010 |
Choosing asthma step-up care.
Topics: Acetates; Adolescent; Albuterol; Androstadienes; Asthma; Bronchodilator Agents; Child; Cyclopropanes; Drug Therapy, Combination; Fluticasone; Humans; Quinolines; Salmeterol Xinafoate; Sulfides | 2010 |
An academic perspective on the APPEs' educational significance.
Topics: Accreditation; Acetates; Citalopram; Cyclopropanes; Drug Labeling; Education, Pharmacy; Evidence-Based Medicine; Humans; Leukotriene Antagonists; Omeprazole; Practice Guidelines as Topic; Problem-Based Learning; Proton Pump Inhibitors; Quinolines; Schools, Pharmacy; Selective Serotonin Reuptake Inhibitors; Sulfides; United States | 2009 |
Antitussive effects of the leukotriene receptor antagonist montelukast in patients with cough variant asthma and atopic cough.
Topics: Acetates; Adult; Aged; Antitussive Agents; Asthma; Clenbuterol; Cough; Cyclopropanes; Drug Therapy, Combination; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Respiratory Function Tests; Sulfides; Treatment Outcome | 2010 |
Cysteinyl leukotriene receptor antagonists inhibit tumor metastasis by inhibiting capillary permeability.
Topics: Acetates; Animals; Capillary Permeability; Carcinoma, Lewis Lung; Cell Line, Tumor; Chromones; Colonic Neoplasms; Cyclopropanes; Female; Leukotriene Antagonists; Male; Mice; Neoplasm Metastasis; Neoplastic Cells, Circulating; Quinolines; Rats; Rats, Inbred F344; Sulfides | 2010 |
Combined cetirizine-montelukast preventive treatment for food-dependent exercise-induced anaphylaxis.
Topics: Acetates; Adolescent; Anaphylaxis; Anti-Allergic Agents; Anti-Asthmatic Agents; Cetirizine; Cyclopropanes; Drug Therapy, Combination; Exercise; Food Hypersensitivity; Humans; Male; Prunus; Quinolines; Sulfides | 2010 |
sCD14 in bronchoalveolar lavage 18, 42 and 162 hours after segmental allergen provocation.
Topics: Acetates; Adolescent; Adult; Allergens; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cyclopropanes; Enzyme-Linked Immunosorbent Assay; Female; Humans; Leukotriene Antagonists; Leukotriene D4; Lipopolysaccharide Receptors; Lipopolysaccharides; Male; Quinolines; Sulfides; Time; Young Adult | 2010 |
Interactive inhibitory effects of formoterol and montelukast on activated human neutrophils.
Topics: Acetates; Adrenergic beta-2 Receptor Agonists; Adult; Albuterol; Calcium Channels; CD18 Antigens; Cyclic AMP; Cyclopropanes; Cytochalasin B; Drug Interactions; Ethanolamines; Formoterol Fumarate; Humans; Leukotriene Antagonists; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Pancreatic Elastase; Quinolines; Rolipram; Sulfides; Superoxides | 2010 |
Synergistic organocatalysis in the kinetic resolution of secondary thiols with concomitant desymmetrization of an anhydride.
Topics: Acetates; Anhydrides; Anti-Asthmatic Agents; Catalysis; Cyclopropanes; Kinetics; Molecular Structure; Quinolines; Stereoisomerism; Sulfhydryl Compounds; Sulfides | 2010 |
Montelukast during primary infection prevents airway hyperresponsiveness and inflammation after reinfection with respiratory syncytial virus.
Topics: Acetates; Animals; Animals, Newborn; Anti-Asthmatic Agents; Bronchiolitis, Viral; Bronchoalveolar Lavage Fluid; Cyclopropanes; Cysteine; Disease Models, Animal; Inflammation; Interferon-gamma; Leukotriene Antagonists; Leukotrienes; Mice; Mice, Inbred BALB C; Quinolines; Recurrence; Respiratory Hypersensitivity; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Sulfides | 2010 |
Concomitant activity of histamine and cysteinyl leukotrienes on porcine nasal mucosal vessels and nasal inflammation in the rat.
Topics: Acetates; Animals; Cyclopropanes; Cysteine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Histamine; Histamine H1 Antagonists, Non-Sedating; Hypersensitivity; In Vitro Techniques; Leukotriene Antagonists; Leukotriene D4; Leukotrienes; Loratadine; Male; Nasal Mucosa; Neutrophil Infiltration; Quinolines; Rats; Rats, Inbred BN; Rhinitis; Sulfides; Sus scrofa | 2010 |
Montelukast prevents vascular endothelial dysfunction from internal combustion exhaust inhalation during exercise.
Topics: Acetates; Air Pollutants; Brachial Artery; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Exercise Test; Humans; Leukotriene Antagonists; Male; Microcirculation; Oxygen Consumption; Quinolines; Regional Blood Flow; Sulfides; Vasoconstriction; Vasodilation; Vehicle Emissions; Young Adult | 2010 |
Montelukast, a selective cysteinyl leukotriene receptor 1 antagonist, reduces cerulein-induced pancreatic injury in rats.
Topics: Acetates; Acute Disease; Animals; Ceruletide; Cyclopropanes; Cytokines; Female; Glutathione; Leukotriene Antagonists; Leukotriene B4; Lipid Peroxidation; Male; Pancreas; Pancreatitis; Peroxidase; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Leukotriene; Sodium-Potassium-Exchanging ATPase; Sulfides | 2010 |
Treatment with the leukotriene inhibitor montelukast for 10 days attenuates portal hypertension in rat liver cirrhosis.
Topics: Acetates; Animals; Cyclopropanes; Hypertension, Portal; Kupffer Cells; Leukotriene Antagonists; Leukotrienes; Ligation; Liver; Liver Cirrhosis; Male; Quinolines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Sulfides; Thioacetamide; Thromboxane A2 | 2010 |
Prevention of Escherichia coli K1 penetration of the blood-brain barrier by counteracting the host cell receptor and signaling molecule involved in E. coli invasion of human brain microvascular endothelial cells.
Topics: Acetates; Animals; Animals, Newborn; Blood-Brain Barrier; Brain; Cells, Cultured; Cyclopropanes; Endothelial Cells; Escherichia coli; Etoposide; Female; Humans; Leukotriene Antagonists; Meningitis, Escherichia coli; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Laminin; Sulfides | 2010 |
Interactive medical case. A rash hypothesis.
Topics: Acetates; Adult; Anti-Inflammatory Agents; Cromolyn Sodium; Cyclopropanes; Diarrhea; Drug Therapy, Combination; Enzyme Inhibitors; Exanthema; Female; Flushing; Histamine H2 Antagonists; Humans; Leukotriene Antagonists; Mastocytosis, Systemic; Prednisone; Protein-Tyrosine Kinases; Quinolines; Ranitidine; Staurosporine; Sulfides; Tryptases; Vomiting | 2010 |
Malabsorption syndrome and leukotriene inhibitor.
Topics: Acetates; Child; Cyclopropanes; Diagnosis, Differential; Diarrhea; Endoscopy, Gastrointestinal; Enteritis; Eosinophilia; Female; Gastritis; Humans; Leukotriene Antagonists; Malabsorption Syndromes; Quinolines; Sulfides; Treatment Outcome | 2011 |
Effects of combination therapy with montelukast and carbocysteine in allergen-induced airway hyperresponsiveness and airway inflammation.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Carbocysteine; Cyclopropanes; Dexamethasone; Drug Synergism; Drug Therapy, Combination; Eosinophils; Female; Inflammation; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; Ovalbumin; Quinolines; Sulfides | 2010 |
Churg-Strauss syndrome with severe granulomatous angiitis and crescentic glomerulonephritis, which developed during therapy with a leukotriene receptor antagonist.
Topics: Acetates; Aged; Antibodies, Antineutrophil Cytoplasmic; Asthma; C-Reactive Protein; Churg-Strauss Syndrome; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Prednisolone; Quinolines; Sulfides; Vasculitis, Central Nervous System | 2010 |
Montelukast treatment (cysteinyl leukotriene receptor antagonist) in a model of food allergy: modifications in lymphatic cell population from rectal mucosa.
Topics: Acetates; Animals; Cyclopropanes; Disease Models, Animal; Food Hypersensitivity; Intestinal Mucosa; Leukotriene Antagonists; Quinolines; Rabbits; Sulfides | 2010 |
Dual inhibition of wound healing and oxidative process by montelukast in experimental colon anastomoses.
Topics: Acetates; Anastomosis, Surgical; Animals; Colon; Cyclopropanes; Disease Models, Animal; Leukotriene Antagonists; Oxidative Stress; Quinolines; Rats; Rats, Wistar; Sulfides; Treatment Outcome; Wound Healing | 2010 |
Blockade of cysteinyl leukotriene-1 receptors suppresses airway remodelling in mice overexpressing GATA-3.
Topics: Acetates; Airway Remodeling; Animals; Cyclopropanes; Disease Models, Animal; GATA3 Transcription Factor; Mice; Mice, Inbred BALB C; Mice, Transgenic; Quinolines; Receptors, Leukotriene; Reverse Transcriptase Polymerase Chain Reaction; Sulfides; Th2 Cells | 2011 |
Patient characteristics and prescription fill patterns for allergic rhinitis medications, with a focus on montelukast, in a commercially insured population.
Topics: Acetates; Adolescent; Adult; Age Factors; Anti-Asthmatic Agents; Child; Child, Preschool; Cohort Studies; Cyclopropanes; Drug Utilization; Female; Humans; Insurance Claim Review; Insurance, Health; Insurance, Pharmaceutical Services; Male; Medication Adherence; Middle Aged; Quinolines; Residence Characteristics; Retrospective Studies; Rhinitis, Allergic, Seasonal; Sex Factors; Sulfides; Young Adult | 2010 |
Leukotriene D4 receptor antagonist montelukast alleviates protamine sulphate-induced changes in rat urinary bladder.
Topics: Acetates; Animals; Cell Count; Cyclopropanes; Cystitis, Interstitial; Disease Models, Animal; Female; Glutathione; Glycosaminoglycans; Immunohistochemistry; Leukotriene Antagonists; Malondialdehyde; Mast Cells; Microscopy, Electron, Transmission; Protamines; Quinolines; Rats; Rats, Wistar; Sulfides; Tryptases; Urinary Bladder; Urothelium | 2011 |
Leukotrienes produced in allergic lung inflammation activate alveolar macrophages.
Topics: Acetates; Allergens; Animals; Asthma; Cyclopropanes; Cysteine; Disease Models, Animal; Klebsiella pneumoniae; Leukotriene Antagonists; Leukotriene C4; Leukotrienes; Lung; Macrophages, Alveolar; Male; Nitric Oxide; Ovalbumin; Phagocytosis; Pneumonia; Quinolines; Rats; Rats, Wistar; Receptors, IgG; Sulfides | 2010 |
Protective effect of montelukast against quinolinic acid/malonic acid induced neurotoxicity: possible behavioral, biochemical, mitochondrial and tumor necrosis factor-α level alterations in rats.
Topics: Acetates; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Brain; Brain Chemistry; Catalase; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Gene Expression Regulation; Lipid Peroxidation; Male; Malonates; Mitochondria; Motor Activity; Neuroprotective Agents; Neurotoxicity Syndromes; Nitrites; Quinolines; Quinolinic Acid; Rats; Rats, Wistar; Sulfides; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2010 |
Safety of using montelukast during pregnancy.
Topics: Abnormalities, Drug-Induced; Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Pregnancy; Pregnancy Complications; Quinolines; Sulfides | 2010 |
Protective effects of montelukast on ischemia-reperfusion injury in rat ovaries subjected to torsion and detorsion: biochemical and histopathologic evaluation.
Topics: Acetates; Animals; Antioxidants; Cyclopropanes; Female; Ovarian Diseases; Oxidative Stress; Protective Agents; Quinolines; Rats; Rats, Wistar; Reperfusion Injury; Sulfides | 2011 |
Montelukast might improve compliance with subcutaneous immunotherapy treatments in patients with allergic asthma.
Topics: Acetates; Allergens; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Desensitization, Immunologic; Humans; Hypersensitivity; Injections, Subcutaneous; Patient Compliance; Quinolines; Sulfides | 2011 |
[New approaches to treatment of occupational bronchial asthma].
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclic AMP; Cyclic GMP; Cyclopropanes; Humans; Leukotriene Antagonists; Occupational Diseases; Quinolines; Sulfides | 2010 |
De novo development of eosinophilic myocarditis with left ventricular assist device support as bridge to transplant.
Topics: Acetates; Cardiomyopathy, Dilated; Cyclopropanes; Eosinophilia; Female; Heart Transplantation; Heart-Assist Devices; Humans; Leukotriene Antagonists; Middle Aged; Myocarditis; Quinolines; Sulfides; Thrombosis | 2010 |
Effects of montelukast, a cysteinyl-leukotriene type 1 receptor antagonist, on the pathogenesis of bleomycin-induced pulmonary fibrosis in mice.
Topics: Acetates; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Cyclopropanes; Cytokines; Female; Gene Expression Regulation; Hydroxyproline; Leukotriene Antagonists; Lung; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Quinolines; Receptors, Leukotriene; RNA, Messenger; Sulfides | 2011 |
The effects of methylprednisolone, montelukast and indomethacine in experimental otitis media with effusion.
Topics: Acetates; Administration, Oral; Animals; Biopsy, Needle; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Immunohistochemistry; Indomethacin; Injections, Intraperitoneal; Male; Methylprednisolone; Otitis Media with Effusion; Otoscopy; Quinolines; Random Allocation; Rats; Rats, Wistar; Reference Values; Statistics, Nonparametric; Sulfides; Treatment Outcome | 2011 |
Stability indicating method for sodium montelukast in pharmaceutical preparations by micellar electrokinetic capillary chromatography.
Topics: Acetates; Buffers; Chromatography, High Pressure Liquid; Chromatography, Micellar Electrokinetic Capillary; Cyclopropanes; Drug Stability; Electrochemistry; Hydrogen-Ion Concentration; Indicators and Reagents; Leukotriene Antagonists; Quinolines; Reference Standards; Reproducibility of Results; Solutions; Sulfides; Tablets | 2010 |
Observations on use of montelukast in pediatric eosinophilic esophagitis: insights for the future.
Topics: Acetates; Adolescent; Child; Child, Preschool; Cyclopropanes; Eosinophilic Esophagitis; Esophagitis; Esophagus; Female; Follow-Up Studies; Humans; Leukotriene Antagonists; Male; Quinolines; Retrospective Studies; Sulfides; Treatment Outcome; Young Adult | 2011 |
Antispasmodic effects of eugenol on rat airway smooth muscle.
Topics: Acetates; Animals; Calcium; Calcium Channels; Cyclopropanes; Dose-Response Relationship, Drug; Electric Stimulation; Eugenol; Indomethacin; Inhibitory Concentration 50; Male; Muscle Contraction; Muscle, Smooth; Quinolines; Rats; Rats, Wistar; Sarcoplasmic Reticulum; Sulfides; Trachea | 2011 |
Involvement of cysteinyl leukotriene receptors in angiogenesis in rat thoracic aortic rings.
Topics: Acetates; Animals; Aorta, Thoracic; Capillaries; Culture Media, Serum-Free; Cyclopropanes; Leukotriene Antagonists; Leukotriene D4; Neovascularization, Pathologic; Organ Culture Techniques; Quinolines; Rats; Receptors, Leukotriene; Sulfides | 2010 |
Inhibition of leukotriene C4 action reduces oxidative stress and apoptosis in cardiomyocytes and impedes remodeling after myocardial injury.
Topics: Acetates; Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Cyclopropanes; Echocardiography; Heart Ventricles; Leukotriene C4; Male; Mice; Mice, Transgenic; Myocardial Ischemia; Myocytes, Cardiac; Oxidative Stress; Quinolines; Reactive Oxygen Species; Sulfides; Ventricular Remodeling | 2011 |
Fluticasone, azithromycin and montelukast therapy in reducing corticosteroid exposure in bronchiolitis obliterans syndrome after allogeneic hematopoietic SCT: a case series of eight patients.
Topics: Acetates; Adrenal Cortex Hormones; Adult; Androstadienes; Azithromycin; Bronchiolitis Obliterans; Cyclopropanes; Female; Fluticasone; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Male; Middle Aged; Quinolines; Retrospective Studies; Sulfides; Transplantation, Homologous; Young Adult | 2011 |
Effects of montelukast on burn wound healing in a rat model.
Topics: Acetates; Animals; Anti-Bacterial Agents; Burns; Cyclopropanes; Leukotriene Antagonists; Male; Neutrophil Infiltration; Quinolines; Random Allocation; Rats; Rats, Sprague-Dawley; Sulfides; Wound Healing | 2010 |
Oral montelukast may have a role in severe and in life-threatening acute asthma.
Topics: Acetates; Acute Disease; Administration, Oral; Adult; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Humans; Quinolines; Sulfides | 2011 |
Lack of pretreatment cost-effectiveness and side effects of omalizumab versus prednisone/montelukast on tolerability of immunotherapy.
Topics: Acetates; Anti-Asthmatic Agents; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Asthma; Cost-Benefit Analysis; Cyclopropanes; Desensitization, Immunologic; Humans; Hypersensitivity; Omalizumab; Prednisone; Quinolines; Sulfides | 2011 |
Reevaluation of the microsomal metabolism of montelukast: major contribution by CYP2C8 at clinically relevant concentrations.
Topics: Acetates; Aryl Hydrocarbon Hydroxylases; Cyclopropanes; Cytochrome P-450 CYP2C8; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Isoenzymes; Leukotriene Antagonists; Leukotrienes; Microsomes, Liver; Models, Theoretical; Oxidation-Reduction; Quinolines; Recombinant Proteins; Sulfides; Time Factors | 2011 |
Polymorphisms of the PTGDR and LTC4S influence responsiveness to leukotriene receptor antagonists in Korean children with asthma.
Topics: Acetates; Asthma; Child; Cyclopropanes; Exercise Test; Fluorescence; Genome-Wide Association Study; Genotype; Glutathione Transferase; Humans; Immunoenzyme Techniques; Immunoglobulin E; Korea; Leukotriene Antagonists; Odds Ratio; Phenotype; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Quinolines; Receptors, Immunologic; Receptors, Prostaglandin; Sulfides | 2011 |
Montelukast in childhood asthma: what is the evidence for its use?
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Bronchoconstriction; Child; Child, Preschool; Cyclopropanes; Dose-Response Relationship, Drug; Humans; Leukotriene Antagonists; Leukotrienes; Quinolines; Sulfides; Treatment Outcome | 2011 |
Detecting unexpected adverse drug reactions in children.
Topics: Acetates; Adolescent; Adverse Drug Reaction Reporting Systems; Asthma, Exercise-Induced; Child; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Humans; Hypersensitivity; Male; Quinolines; Research Report; Sulfides | 2011 |
Effect of leukotriene receptor antagonists on lung fibrosis in rats.
Topics: Acetates; Animals; Bleomycin; Collagen; Cyclopropanes; Dose-Response Relationship, Drug; Drug Combinations; Hydroxyproline; Leukotriene Antagonists; Lung; Male; Prednisone; Pulmonary Fibrosis; Quinolines; Rats; Sulfides | 2011 |
Leukotriene-induced contraction is mediated by cysteinyl leukotriene receptor CysLT1 in guinea pig fundus but by CysLT1 and CysLT2 in antrum.
Topics: Acetates; Animals; Cyclopropanes; Dose-Response Relationship, Drug; Gastric Fundus; Guinea Pigs; Leukotriene C4; Leukotriene D4; Leukotriene E4; Male; Muscle Contraction; Pyloric Antrum; Quinolines; Receptors, Leukotriene; SRS-A; Sulfides | 2011 |
Clinical trials and tribulations: the MASCOT study.
Topics: Acetates; Adrenergic beta-Agonists; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Drug Therapy, Combination; Glucocorticoids; Humans; Patient Selection; Quinolines; Randomized Controlled Trials as Topic; Research Design; Sulfides | 2011 |
Montelukast, a cysteinyl leukotriene receptor-1 antagonist, attenuates chronic brain injury after focal cerebral ischaemia in mice and rats.
Topics: Acetates; Administration, Oral; Animals; Antipyrine; Atrophy; Behavior, Animal; Brain Injury, Chronic; Chromones; Cyclopropanes; Disease Models, Animal; Drug Evaluation, Preclinical; Edaravone; Free Radical Scavengers; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Leukotriene Antagonists; Male; Mice; Mice, Inbred ICR; Nerve Degeneration; Quinolines; Rats; Rats, Sprague-Dawley; Sulfides | 2011 |
Montelukast for bronchiolitis obliterans syndrome after lung transplantation: a pilot study.
Topics: Acetates; Azithromycin; Bronchiolitis Obliterans; Cyclopropanes; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Lung Transplantation; Male; Middle Aged; Pilot Projects; Quinolines; Sulfides; Treatment Outcome | 2011 |
The effects of leukotriene receptor antagonist montelukast on histological, radiological and densitometric parameters of fracture healing.
Topics: Absorptiometry, Photon; Acetates; Animals; Bone Density; Cyclopropanes; Female; Fracture Healing; Fractures, Closed; Leukotriene Antagonists; Quinolines; Random Allocation; Rats; Rats, Wistar; Sulfides; Tibial Fractures; Treatment Outcome | 2011 |
Ontology-based knowledge discovery in pharmacogenomics.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Computational Biology; Cyclopropanes; Data Interpretation, Statistical; Data Mining; Databases, Genetic; Genetic Association Studies; Humans; Knowledge Bases; Logistic Models; Pharmacogenetics; Quinolines; Sulfides | 2011 |
[Effects of agonist and antagonist of cysteinyl leukotriene receptors on differentiation of rat glioma C6 cells].
Topics: Acetates; Animals; Cell Differentiation; Cell Line, Tumor; Colforsin; Cyclopropanes; Cysteine; Glioma; Leukotriene Antagonists; Leukotriene D4; Leukotrienes; Quinolines; Rats; Receptors, Leukotriene; Sulfides | 2011 |
The effect of montelukast in a model of gouty arthritis induced by sodium monourate crystals.
Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Cell Migration Assays, Leukocyte; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Indomethacin; Inflammation; Leukocytes, Mononuclear; Leukotriene Antagonists; Male; Mice; Mice, Inbred BALB C; Neutrophils; Premedication; Quinolines; Sulfides; Uric Acid | 2011 |
Association of the variants in AGT gene with modified drug response in Korean aspirin-intolerant asthma patients.
Topics: Acetates; Adolescent; Adult; Aged; Algorithms; Angiotensinogen; Anti-Asthmatic Agents; Asian People; Aspirin; Asthma, Aspirin-Induced; Bronchial Spasm; Case-Control Studies; Cyclopropanes; Drug Hypersensitivity; Female; Genetic Predisposition to Disease; Genetic Variation; Genotype; Haplotypes; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Quinolines; Republic of Korea; Sulfides; Young Adult | 2011 |
Modulation of leukotriene D4 attenuates the development of seizures in mice.
Topics: Acetates; Animals; Cyclopropanes; Dose-Response Relationship, Drug; gamma-Glutamyltransferase; Leukotriene Antagonists; Leukotriene D4; Male; Mice; Models, Animal; Pilocarpine; Quinolines; Receptors, Leukotriene; Seizures; Sulfides; Tetrahydroisoquinolines | 2011 |
Effects of a cysteinyl leukotriene dual 1/2 receptor antagonist on antigen-induced airway hypersensitivity and airway inflammation in a guinea pig asthma model.
Topics: Acetates; Acetylcholine; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cyclopropanes; Eosinophils; Guinea Pigs; Inflammation; Leukotriene Antagonists; Lung; Male; Ovalbumin; Quinolines; Receptors, Leukotriene; SRS-A; Sulfides | 2011 |
Eosinophilic gastrointestinal disorders (EGID) with peripheral eosinophilia: a retrospective review at Mayo Clinic.
Topics: Acetates; Adolescent; Adult; Aged; Antibodies, Monoclonal; Antineoplastic Agents; Biomarkers; Cyclopropanes; Enteritis; Eosinophilia; Female; Gastritis; Gastrointestinal Tract; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Retrospective Studies; Sulfides; Young Adult | 2011 |
Montelukast was inefficient in maintaining steroid-induced remission in adult eosinophilic esophagitis.
Topics: Acetates; Adult; Androstadienes; Anti-Inflammatory Agents; Biopsy; Cyclopropanes; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endoscopy, Gastrointestinal; Eosinophilic Esophagitis; Female; Fluticasone; Follow-Up Studies; Humans; Leukotriene Antagonists; Male; Middle Aged; Patient Satisfaction; Prospective Studies; Quinolines; Remission Induction; Sulfides; Surveys and Questionnaires; Treatment Outcome; Young Adult | 2011 |
Montelukast attenuates side effects of cisplatin including testicular, spermatological, and hormonal damage in male rats.
Topics: Acetates; Administration, Oral; Animals; Antineoplastic Agents; Cisplatin; Cyclopropanes; Injections, Intraperitoneal; Leukotriene Antagonists; Male; Oxidative Stress; Quinolines; Rats; Rats, Sprague-Dawley; Reproduction; Sperm Motility; Spermatozoa; Sulfides; Testis; Testosterone; Thiobarbituric Acid Reactive Substances | 2012 |
Successful treatment of eosinophilia-associated Budd-Chiari syndrome in a child.
Topics: Abdominal Pain; Acetates; Angioplasty; Ascites; Budd-Chiari Syndrome; Child; Constriction, Pathologic; Cyclopropanes; Diagnosis, Differential; Humans; Hypereosinophilic Syndrome; Leukotriene Antagonists; Male; Quinolines; Sulfides; Treatment Outcome; Vena Cava, Inferior | 2011 |
Evaluation of CYP2C8 inhibition in vitro: utility of montelukast as a selective CYP2C8 probe substrate.
Topics: Acetates; Amodiaquine; Aryl Hydrocarbon Hydroxylases; Binding Sites; Carbamates; Cyclopropanes; Cytochrome P-450 CYP2C8; Drug Interactions; Humans; Microsomes, Liver; Paclitaxel; Piperidines; Quinolines; Rosiglitazone; Sensitivity and Specificity; Substrate Specificity; Sulfides; Thiazolidinediones | 2011 |
[Association of leukotriene gene polymorphisms with response to antileukotriene treatment in patients with asthma].
Topics: Acetates; Adolescent; Adult; Alleles; Asthma; Case-Control Studies; Cyclopropanes; Female; Gene Frequency; Genotype; Haplotypes; Humans; Leukotriene Antagonists; Leukotrienes; Male; Middle Aged; Polymorphism, Single Nucleotide; Quinolines; Sulfides; Young Adult | 2011 |
[Antileukotrienes in asthma: a nice story, still to be completed].
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2011 |
The effects of montelukast on antioxidant enzymes and proinflammatory cytokines on the heart, liver, lungs, and kidneys in a rat model of cecal ligation and puncture-induced sepsis.
Topics: Acetates; Animals; Cecum; Cyclopropanes; Cytokines; Disease Models, Animal; Glutathione; Heart; Kidney; Lipid Peroxides; Liver; Lung; Multiple Organ Failure; Myocardium; Peroxidase; Protective Agents; Quinolines; Rats; Reactive Oxygen Species; Sepsis; Sulfides; Superoxide Dismutase | 2011 |
Differential inhibitory effects of CysLT(1) receptor antagonists on P2Y(6) receptor-mediated signaling and ion transport in human bronchial epithelia.
Topics: Acetates; Bronchi; Calcium; Cell Line; Chlorides; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclopropanes; Electric Conductivity; Enzyme Activation; Gene Expression Regulation; Guanine Nucleotide Exchange Factors; Humans; Ion Transport; Leukotriene Antagonists; Quinolines; Receptors, Leukotriene; Receptors, Purinergic P2; Respiratory Mucosa; Signal Transduction; Sulfides; Uridine Diphosphate | 2011 |
Stability indicating LC method to determination of sodium montelukast in pharmaceutical dosage form and its photodegradation kinetics.
Topics: Acetates; Chromatography, High Pressure Liquid; Cyclopropanes; Dosage Forms; Drug Stability; Kinetics; Photolysis; Quinolines; Sensitivity and Specificity; Sulfides | 2011 |
Antiasthmatic drugs targeting the cysteinyl leukotriene receptor 1 alleviate central nervous system inflammatory cell infiltration and pathogenesis of experimental autoimmune encephalomyelitis.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Blood-Brain Barrier; Blotting, Western; Cell Separation; Cyclopropanes; Encephalomyelitis, Autoimmune, Experimental; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Fluorescent Antibody Technique; Indoles; Inflammation; Mice; Mice, Inbred C57BL; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Spinal Cord; Sulfides; Sulfonamides; Tosyl Compounds | 2011 |
Effects of cysteinyl-leukotriene receptors' antagonism by montelukast on lung mechanics and olfactory system histology in healthy mice.
Topics: Acetates; Animals; Cyclopropanes; Injections, Intraperitoneal; Leukotriene Antagonists; Lung; Male; Mice; Olfactory Mucosa; Quinolines; Receptors, Leukotriene; Structure-Activity Relationship; Sulfides | 2012 |
Montelukast for symptom control of interstitial cystitis.
Topics: Acetates; Cyclopropanes; Cystitis, Interstitial; Humans; Leukotriene Antagonists; Male; Middle Aged; Quality of Life; Quinolines; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sulfides | 2011 |
Montelukast ameliorates kidney function and urinary bladder sensitivity in experimentally induced renal dysfunction in rats.
Topics: Acetates; Acetylcholine; Animals; Antineoplastic Agents; Antioxidants; Blood Urea Nitrogen; Cisplatin; Creatinine; Cyclopropanes; Glutathione; Kidney; L-Lactate Dehydrogenase; Lipid Peroxides; Male; Malondialdehyde; Oxidative Stress; Quinolines; Random Allocation; Rats; Rats, Sprague-Dawley; Renal Insufficiency; Serum Albumin; Sulfides; Superoxide Dismutase; Urinary Bladder | 2013 |
Congenital malformations among infants born to women receiving montelukast, inhaled corticosteroids, and other asthma medications.
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Congenital Abnormalities; Cyclopropanes; Female; Humans; Infant; Pregnancy; Quinolines; Sulfides | 2012 |
A case of Churg-Strauss syndrome treated with montelukast.
Topics: Acetates; Asthma; Churg-Strauss Syndrome; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Middle Aged; Quinolines; Sulfides | 2012 |
Clinical, physiological and anti-inflammatory effect of montelukast in patients with cough variant asthma.
Topics: Acetates; Adult; Aged; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cohort Studies; Cough; Cyclopropanes; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Leukotriene Antagonists; Linear Models; Male; Methacholine Chloride; Middle Aged; Multivariate Analysis; Odds Ratio; Prospective Studies; Quinolines; Respiratory Function Tests; Risk Assessment; Severity of Illness Index; Sulfides; Treatment Outcome | 2012 |
[Pathogenesis, diagnosis and therapy of bronchial asthma. How can the lungs be freed?].
Topics: Acetates; Administration, Inhalation; Adult; Airway Obstruction; Asthma; Atherosclerosis; Bronchodilator Agents; Bronchoscopy; Child; Cyclopropanes; Glucocorticoids; Humans; Hyperthermia, Induced; Leukotriene Antagonists; Quinolines; Scopolamine Derivatives; Sulfides; Tiotropium Bromide | 2011 |
Inhibition of leukotriene receptors boosts neural progenitor proliferation.
Topics: Acetates; Animals; Cell Proliferation; Cyclopropanes; Female; Leukotriene Antagonists; Leukotrienes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neural Stem Cells; Neurogenesis; Phosphorylation; Quinolines; Rats; Receptors, G-Protein-Coupled; Receptors, Leukotriene; Signal Transduction; Sulfides | 2011 |
Anti-cholinergic effect of singulair on isolated rat's tracheal smooth muscle.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Bronchoconstrictor Agents; Cholinergic Antagonists; Cyclopropanes; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Methacholine Chloride; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Quinolines; Rats; Sulfides; Trachea | 2012 |
Characterization of a model of tracheal plasma extravasation in passively sensitized rats using anti-allergic and anti-inflammatory drugs by oral and intratracheal route.
Topics: Acetates; Administration, Oral; Androstadienes; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Cell Degranulation; Cetirizine; Cromolyn Sodium; Cyclopropanes; Dinitrophenols; Fluticasone; Immunization, Passive; Indicators and Reagents; Intracellular Signaling Peptides and Proteins; Intubation, Intratracheal; Male; Mast Cells; Oxazines; Plasma; Protein-Tyrosine Kinases; Pyridines; Quinolines; Rats; Rats, Wistar; Sulfides; Syk Kinase; Trachea | 2012 |
Nationwide cohort study of the leukotriene receptor antagonist montelukast and incident or recurrent cardiovascular disease.
Topics: Acetates; Aged; Asthma; Cardiovascular Diseases; Cohort Studies; Comorbidity; Cyclopropanes; Drug Utilization; Female; Follow-Up Studies; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Risk; Sex Factors; Socioeconomic Factors; Sulfides; Survival Analysis; Sweden | 2012 |
Higher levels of soluble Fas ligand and transforming growth factor-β after omalizumab treatment: a case report.
Topics: Acetates; Adolescent; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal, Humanized; Apoptosis; Asthma; Budesonide; Cyclopropanes; Fas Ligand Protein; Female; Humans; Immunologic Factors; Lung; Omalizumab; Quinolines; Respiratory Function Tests; Sulfides; T-Lymphocytes, Regulatory; Transforming Growth Factor beta; Treatment Outcome | 2012 |
Beneficial effects of montelukast against cisplatin-induced acute renal damage in rats.
Topics: Acetates; Acute Kidney Injury; Animals; Blood Urea Nitrogen; Cisplatin; Creatinine; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glutathione; Injections, Intraperitoneal; Kidney; Leukotriene Antagonists; Malondialdehyde; Oxidative Stress; Peroxidase; Quinolines; Rats; Rats, Wistar; Spectrophotometry; Sulfides; Treatment Outcome | 2012 |
Cost, utilization, and patterns of medication use associated with chronic idiopathic urticaria.
Topics: Acetates; Administration, Oral; Adolescent; Adrenal Cortex Hormones; Adult; Angioedema; Chronic Disease; Cross-Sectional Studies; Cyclopropanes; Doxepin; Drug Prescriptions; Fees, Pharmaceutical; Female; Health Care Costs; Histamine Antagonists; Humans; Insurance Claim Review; Male; Middle Aged; Practice Patterns, Physicians'; Quinolines; Sulfides; Urticaria; Young Adult | 2012 |
Montelukast as a treatment modality for eosinophilic gastroenteritis.
Topics: Acetates; Adult; Cyclopropanes; Eosinophilia; Gastroenteritis; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2011 |
Influence of inhaled beclomethasone and montelukast on airway remodeling in mice.
Topics: Acetates; Administration, Inhalation; Airway Remodeling; Animals; Anti-Asthmatic Agents; Asthma; Beclomethasone; Cyclopropanes; Disease Models, Animal; Inflammation; Male; Mice; Ovalbumin; Quinolines; Severity of Illness Index; Sulfides; Time Factors | 2013 |
Pharmacogenetics of asthma controller treatment.
Topics: Acetates; Administration, Inhalation; Adolescent; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Clinical Trials as Topic; Cyclopropanes; Drug Combinations; Female; Fluticasone; Forced Expiratory Volume; Genetic Association Studies; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Precision Medicine; Quinolines; Receptors, Adrenergic, beta-2; Salmeterol Xinafoate; Sulfides | 2013 |
A novel prostacyclin agonist protects against airway hyperresponsiveness and remodeling in mice.
Topics: Acetates; Airway Remodeling; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cyclopropanes; Dexamethasone; Epoprostenol; Female; Goblet Cells; Hepatocyte Growth Factor; Inflammation; Lung; Metaplasia; Mice; Mice, Inbred BALB C; Muscle, Smooth; Ovalbumin; Pulmonary Fibrosis; Pyridines; Quinolines; Receptors, Leukotriene; Sulfides; Thromboxanes; Up-Regulation | 2012 |
Montelukast abrogates rhabdomyolysis-induced acute renal failure via rectifying detrimental changes in antioxidant profile and systemic cytokines and apoptotic factors production.
Topics: Acetates; alpha-Tocopherol; Animals; Anti-Asthmatic Agents; Antioxidants; Cyclopropanes; Cytokines; Fas-Associated Death Domain Protein; Glycerol; Kidney; Kidney Tubular Necrosis, Acute; Leukotriene Antagonists; Male; Malondialdehyde; Oxidative Stress; Oxidoreductases; Quinolines; Random Allocation; Rats; Rats, Wistar; Receptors, Leukotriene; Rhabdomyolysis; Sulfides | 2012 |
Efficacy of montelukast as added therapy in patients with chronic idiopathic urticaria.
Topics: Acetates; Adolescent; Adult; Aged; Chronic Disease; Cyclopropanes; Drug Therapy, Combination; Female; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Immunoglobulin E; Leukotriene Antagonists; Male; Middle Aged; Practice Guidelines as Topic; Quinolines; Retrospective Studies; Sulfides; Treatment Outcome; Urticaria; Young Adult | 2012 |
Ameliorative potential of montelukast on ischemia-reperfusion injury induced vasculitic neuropathic pain in rat.
Topics: Acetates; Animals; Behavior, Animal; Calcium; Cyclopropanes; Glutathione; Hot Temperature; Immersion; Leukotriene Antagonists; Neuralgia; Pain Measurement; Peroxidase; Physical Stimulation; Quinolines; Rats; Rats, Wistar; Reaction Time; Reperfusion Injury; Sciatic Nerve; Sulfides; Thiobarbituric Acid Reactive Substances; Vasculitis | 2012 |
Asthma treatment outcome in children is associated with vascular endothelial growth factor A (VEGFA) polymorphisms.
Topics: Acetates; Androstadienes; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Female; Fluticasone; Forced Expiratory Volume; Humans; Male; Polymorphism, Single Nucleotide; Quinolines; Sulfides; Treatment Outcome; Vascular Endothelial Growth Factor A | 2012 |
Churg-Strauss syndrome related to montelukast.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Churg-Strauss Syndrome; Cough; Cyclopropanes; Dyspnea; Hemoptysis; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2012 |
Beneficial effects of montelukast against methotrexate-induced liver toxicity: a biochemical and histological study.
Topics: Acetates; Animals; Chemical and Drug Induced Liver Injury; Cyclopropanes; Drug Evaluation, Preclinical; Female; Glutathione; Glycogen; Hepatocytes; Liver; Malondialdehyde; Methotrexate; Oxidative Stress; Periodic Acid-Schiff Reaction; Peroxidase; Quinolines; Rats; Rats, Wistar; Sulfides | 2012 |
The leukotriene receptor antagonist montelukast and aortic stenosis.
Topics: Acetates; Aortic Valve Stenosis; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2013 |
Bronchoalveolar lavage fluid exosomes contribute to cytokine and leukotriene production in allergic asthma.
Topics: Acetates; Adult; Allergens; Anti-Asthmatic Agents; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Cyclopropanes; Cytokines; Eosinophils; Epithelial Cells; Exosomes; Female; Humans; Leukotrienes; Male; Middle Aged; Quinolines; Sulfides; Young Adult | 2012 |
The effects of montelukast against amikacin-induced acute renal damage.
Topics: Acetates; Acute Disease; Amikacin; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Blood Urea Nitrogen; Creatinine; Cyclopropanes; Cytoprotection; Disease Models, Animal; Female; Glutathione; Immunohistochemistry; Interleukin-1beta; Kidney; Kidney Diseases; Malondialdehyde; Peroxidase; Quinolines; Rats; Rats, Wistar; Sulfides; Tumor Necrosis Factor-alpha | 2012 |
[Effect of montelukast on morphological changes in neurons after ischemic injury].
Topics: Acetates; Animals; Animals, Newborn; Cell Hypoxia; Cell Survival; Cells, Cultured; Cyclopropanes; Glucose; Leukotriene Antagonists; Neurons; Neuroprotective Agents; Quinolines; Rats; Rats, Sprague-Dawley; Sulfides | 2012 |
Humanized mouse model used to monitor MUC gene expression in nasal polyps and to preclinically evaluate the efficacy of montelukast in reducing mucus production.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Biomarkers, Tumor; Cyclopropanes; Disease Models, Animal; Gene Expression Regulation; Goblet Cells; Humans; Mice; Mice, SCID; Mucin 5AC; Mucin-4; Mucins; Nasal Mucosa; Nasal Polyps; Quinolines; Salivary Proteins and Peptides; Sulfides | 2012 |
Saliva versus plasma pharmacokinetics: theory and application of a salivary excretion classification system.
Topics: Acetates; Anthraquinones; Azithromycin; Benzhydryl Compounds; Cinacalcet; Cloxacillin; Cresols; Cyclopropanes; Female; Fluorobenzenes; Humans; Hydrochlorothiazide; Losartan; Male; Metformin; Naphthalenes; Phenylpropanolamine; Piroxicam; Pyrazines; Pyrimidines; Quinolines; Rosuvastatin Calcium; Saliva; Sitagliptin Phosphate; Sulfides; Sulfonamides; Tamsulosin; Tolterodine Tartrate; Triazoles | 2012 |
Montelukast inhibits leukotriene stimulation of human dendritic cells in vitro.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cell Proliferation; Chemokine CCL5; Coculture Techniques; Cyclopropanes; Dendritic Cells; Humans; Leukotriene C4; Primary Cell Culture; Quinolines; Receptors, Leukotriene; Respiratory Syncytial Viruses; Sulfides; T-Lymphocytes | 2012 |
Cysteinyl leukotriene receptor antagonist montelukast ameliorates acute lung injury following haemorrhagic shock in rats.
Topics: Acetates; Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Cyclopropanes; Glutathione; Interleukin-6; Leukotriene Antagonists; Leukotrienes; Male; Malondialdehyde; Oxidative Stress; Proteins; Quinolines; Rats; Shock, Hemorrhagic; Sulfides; Tumor Necrosis Factor-alpha | 2013 |
[A case of Alice-in-Wonderland syndrome probably associated with the use of montelukast].
Topics: Acetates; Alice in Wonderland Syndrome; Anti-Asthmatic Agents; Child; Cyclopropanes; Female; Humans; Quinolines; Sulfides | 2013 |
Montelukast potentiates the protective effect of rofecoxib against kainic acid-induced cognitive dysfunction in rats.
Topics: Acetates; Acetylcholinesterase; Animals; Antioxidants; Caffeic Acids; Cognition Disorders; Cyclooxygenase 2 Inhibitors; Cyclopropanes; Drug Synergism; Glutathione; Hippocampus; Kainic Acid; Lactones; Leukotriene Antagonists; Lipoxygenase Inhibitors; Maze Learning; Memory; Motor Activity; Neuroprotective Agents; Neurotoxins; Oxidation-Reduction; Oxidative Stress; Quinolines; Rats; Rats, Wistar; Sulfides; Sulfones; Tumor Necrosis Factor-alpha | 2012 |
Effect of grapefruit juice on bioavailability of montelukast.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Beverages; Biological Availability; Citrus paradisi; Cross-Over Studies; Cyclopropanes; Female; Food-Drug Interactions; Humans; Male; Prospective Studies; Quinolines; Sulfides; Young Adult | 2013 |
Montelukast inhibits caspase-3 activity and ameliorates oxidative damage in the spinal cord and urinary bladder of rats with spinal cord injury.
Topics: Acetates; Animals; Behavior, Animal; Caspase 3; Cyclopropanes; Down-Regulation; Glutathione; Interleukin-1beta; Leukotriene Antagonists; Leukotriene B4; Lipid Peroxidation; Luminescent Measurements; Luminol; Malondialdehyde; Neutrophil Infiltration; Neutrophils; Oxidative Stress; Peroxidase; Quinolines; Rats; Rats, Wistar; Spinal Cord; Spinal Cord Injuries; Sulfides; Tumor Necrosis Factor-alpha; Urinary Bladder | 2012 |
Effects of corticosteroid, montelukast and iNOS inhibition on distal lung with chronic inflammation.
Topics: Acetates; Amidines; Animals; Anti-Inflammatory Agents; Benzylamines; Chronic Disease; Cyclopropanes; Cytokines; Dexamethasone; Disease Models, Animal; Enzyme Inhibitors; Eosinophils; Guinea Pigs; Lung; Male; Ovalbumin; Pneumonia; Quinolines; Statistics, Nonparametric; Sulfides | 2013 |
Neuropsychiatric reactions to montelukast.
Topics: Acetates; Adolescent; Asthma; Child; Child Behavior Disorders; Cyclopropanes; Humans; Male; Mood Disorders; Quinolines; Sulfides | 2012 |
Effects of montelukast and zileuton on testicular torsion/detorsion injury in rats.
Topics: Acetates; Animals; Cyclopropanes; Hydroxyurea; Male; Malondialdehyde; Quinolines; Rats; Rats, Wistar; Spermatic Cord Torsion; Sulfides | 2014 |
SLCO2B1 c.935G>A single nucleotide polymorphism has no effect on the pharmacokinetics of montelukast and aliskiren.
Topics: Acetates; Adult; Amides; Antihypertensive Agents; Chromatography, Liquid; Cross-Over Studies; Cyclopropanes; Female; Fumarates; Genotype; Humans; Leukotriene Antagonists; Male; Middle Aged; Organic Anion Transporters; Polymorphism, Single Nucleotide; Quinolines; Radioimmunoassay; Renin; Sulfides; Tandem Mass Spectrometry; Tissue Distribution; Young Adult | 2013 |
Nightmares induced by montelukast in children and adults.
Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Child; Cyclopropanes; Dreams; Female; Humans; Male; Quinolines; Risk; Sleep Initiation and Maintenance Disorders; Spain; Sulfides | 2012 |
The effects of montelukast on eosinophilic gastroenteritis in a mouse model.
Topics: Acetates; Animals; Body Weight; Cyclopropanes; Enteritis; Eosinophilia; Eosinophils; Female; Gastric Mucosa; Gastritis; Gastroenteritis; Immunoglobulin E; Inflammation; Jejunum; Leukotriene D4; Mice; Mice, Inbred BALB C; Ovalbumin; Quinolines; Stomach; Sulfides | 2013 |
Simultaneous determination of montelukast as sparing therapy with some inhaled corticosteroids in plasma of asthmatic patients.
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Adult; Asthma; Chromatography, High Pressure Liquid; Cyclopropanes; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Quinolines; Sulfides | 2013 |
A rare adverse effect of montelukast treatment: ecchymosis.
Topics: Acetates; Adult; Cyclopropanes; Ecchymosis; Female; Humans; Leukotriene Antagonists; Lower Extremity; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides | 2013 |
Protective effect of montelukast which is cysteinyl-leukotriene receptor antagonist on gentamicin-induced nephrotoxicity and oxidative damage in rat kidney.
Topics: Acetates; Acute Kidney Injury; Animals; Anti-Bacterial Agents; Cyclopropanes; Drug Evaluation, Preclinical; Gentamicins; Kidney; Leukotriene Antagonists; Male; Quinolines; Rats; Rats, Wistar; Receptors, Leukotriene; Sulfides; Urine | 2013 |
[Psychiatric disorders associated with montelukast: data from the National Pharmacovigilance Database].
Topics: Acetates; Adolescent; Adult; Aged; Anti-Asthmatic Agents; Child; Child, Preschool; Cyclopropanes; Databases, Factual; Female; France; Humans; Male; Mental Disorders; Middle Aged; Pharmacovigilance; Quinolines; Sulfides; Young Adult | 2013 |
Methacholine PC20 in African Americans and whites with asthma with homozygous genotypes at ADRB2 codon 16.
Topics: Acetates; Adolescent; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Adult; Anti-Asthmatic Agents; Asthma; Black or African American; Bronchial Hyperreactivity; Bronchodilator Agents; Cyclopropanes; Female; Genotype; Histamine Antagonists; Humans; Ipratropium; Male; Methacholine Chloride; Middle Aged; Quinolines; Receptors, Adrenergic, beta-2; Respiratory Function Tests; Sulfides; White People; Young Adult | 2013 |
The efficacy of montelukast as a protective agent against 131I-induced salivary gland damage in rats: scintigraphic and histopathological findings.
Topics: Acetates; Animals; Cyclopropanes; Female; Iodine Radioisotopes; Organ Size; Quinolines; Radiation-Protective Agents; Radionuclide Imaging; Rats; Rats, Wistar; Salivary Glands; Sodium Pertechnetate Tc 99m; Sulfides; Thyroidectomy | 2013 |
Optimal management of DRESS syndrome in course of infectious endocarditis.
Topics: Acetates; Aged; Anti-Bacterial Agents; Cyclopropanes; Drug Eruptions; Endocarditis, Bacterial; Eosinophilia; Humans; Immunoglobulins, Intravenous; Male; Methylprednisolone; Quinolines; Sulfides; Syndrome; Treatment Outcome; Vancomycin | 2013 |
Efficacy of iloprost and montelukast combination on spinal cord ischemia/reperfusion injury in a rat model.
Topics: Acetates; Animals; Biomarkers; Cyclopropanes; Drug Administration Schedule; Drug Therapy, Combination; Iloprost; Injections, Intraperitoneal; Male; Neuroprotective Agents; Oxidative Stress; Quinolines; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Spinal Cord; Spinal Cord Injuries; Sulfides; Treatment Outcome | 2013 |
[Effect of montelukast on the expression of neurokinin-1 receptor in young asthmatic rats with airway remodeling].
Topics: Acetates; Airway Remodeling; Animals; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Female; Leukotriene Antagonists; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; RNA, Messenger; Sulfides | 2013 |
Comparison of the efficacy of KOB03, ketotifen, and montelukast in an experimental mouse model of allergic rhinitis.
Topics: Acetates; Animals; Anti-Allergic Agents; Antigens; Cyclopropanes; Cytokines; Disease Models, Animal; Histamine H1 Antagonists; Immunoglobulin E; Ketotifen; Leukotriene Antagonists; Leukotriene C4; Male; Mice; Mice, Inbred BALB C; Nasal Mucosa; Ovalbumin; Plant Extracts; Quinolines; Rhinitis, Allergic; Rhinitis, Allergic, Perennial; Sulfides | 2013 |
Montelukast can reduce the severity and extent of atopic dermatitis.
Topics: Acetates; Asthma; Child; Clinical Trials as Topic; Cyclopropanes; Dermatitis, Atopic; Humans; Information Storage and Retrieval; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2013 |
Therapeutic potential of curcumin in experimentally induced allergic rhinitis in guinea pigs.
Topics: Acetates; Animals; Cromolyn Sodium; Curcumin; Cyclopropanes; Dose-Response Relationship, Drug; Eosinophil Peroxidase; Female; Gene Expression Regulation; Guinea Pigs; Humidity; Interleukin-4; Male; Nitric Oxide; Ovalbumin; Quinolines; Rhinitis, Allergic; Rhinitis, Allergic, Perennial; Sulfides | 2013 |
A contraction assay system using primary cultured mouse bronchial smooth muscle cells.
Topics: Acetates; Animals; Bronchi; Cells, Cultured; Cyclopropanes; Leukotriene D4; Methacholine Chloride; Mice; Muscle Contraction; Muscle, Smooth; Myocytes, Smooth Muscle; Primary Cell Culture; Quinolines; Sulfides | 2013 |
HAMI 3379, a CysLT2 receptor antagonist, attenuates ischemia-like neuronal injury by inhibiting microglial activation.
Topics: Acetates; Animals; Animals, Newborn; Astrocytes; Brain Ischemia; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Cyclohexanecarboxylic Acids; Cyclopropanes; Cytokines; Female; Glucose; Leukotriene Antagonists; Male; Microglia; Necrosis; Neurons; Oxygen; Phagocytosis; Phthalic Acids; Primary Cell Culture; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Leukotriene; Sulfides | 2013 |
Simultaneous determination of montelukast and fexofenadine using Fourier transform convolution emission data under non- parametric linear regression method.
Topics: Acetates; Calibration; Cyclopropanes; Linear Models; Quinolines; Spectroscopy, Fourier Transform Infrared; Sulfides; Terfenadine | 2013 |
Samter's triad in childhood: a warning for those prescribing NSAIDs.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Asthma, Aspirin-Induced; Bronchodilator Agents; Cranial Sinuses; Critical Care; Cyclopropanes; Epinephrine; Humans; Male; Nasal Polyps; Quinolines; Respiration, Artificial; Respiratory Tract Diseases; Sulfides; Tomography, X-Ray Computed | 2013 |
Mast cell mediators cause early allergic bronchoconstriction in guinea-pigs in vivo: a model of relevance to asthma.
Topics: Acetates; Animals; Asthma; Bronchial Hyperreactivity; Constriction, Pathologic; Cyclopropanes; Disease Models, Animal; Guinea Pigs; Histamine Antagonists; Hypersensitivity; Indomethacin; Leukotriene Antagonists; Lung; Mast Cells; Ovalbumin; Prostaglandin Antagonists; Pyrilamine; Quinolines; Sulfides | 2013 |
[Leukotriene D4 activates BV2 microglia in vitro].
Topics: Acetates; Cell Line; Cell Proliferation; Cyclohexanecarboxylic Acids; Cyclopropanes; Humans; Interleukin-6; Leukotriene Antagonists; Leukotriene D4; Microglia; Phagocytosis; Phthalic Acids; Quinolines; Receptors, Leukotriene; SRS-A; Sulfides | 2013 |
Effects of montelukast on the healing of ischemic colon anastomoses.
Topics: Acetates; Alanine Transaminase; Anastomosis, Surgical; Animals; Aspartate Aminotransferases; Caspase 3; Catalase; Colon; Cyclopropanes; Glutathione; Hydroxyproline; Interleukin-6; Leukotriene Antagonists; Lipid Peroxidation; Male; Malondialdehyde; Models, Animal; Nitric Oxide; Quinolines; Rats; Rats, Wistar; Reperfusion Injury; Sulfides; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Wound Healing | 2013 |
Protective effect of high-dose montelukast on salbutamol-induced homologous desensitisation in airway smooth muscle.
Topics: Acetates; Albuterol; Animals; Bronchi; Bronchodilator Agents; Cell Membrane; Cyclic AMP; Cyclopropanes; Cytosol; Dose-Response Relationship, Drug; Drug Tolerance; Gene Expression Profiling; Guinea Pigs; Humans; Injections, Intraperitoneal; Leukotriene Antagonists; Male; Myocytes, Smooth Muscle; Quinolines; Receptors, Leukotriene; Sulfides; Time Factors; Trachea | 2013 |
Assessment of absorption potential of poorly water-soluble drugs by using the dissolution/permeation system.
Topics: Absorption; Acetates; Administration, Oral; Animals; Area Under Curve; Caco-2 Cells; Celecoxib; Chemistry, Pharmaceutical; Cyclopropanes; Humans; Indoles; Intestinal Absorption; Male; Permeability; Phenylcarbamates; Pyrazoles; Quinolines; Rats; Rats, Wistar; Solubility; Sulfides; Sulfonamides; Technology, Pharmaceutical; Tosyl Compounds; Water | 2013 |
Foxa2 regulates leukotrienes to inhibit Th2-mediated pulmonary inflammation.
Topics: Acetates; Animals; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Cyclopropanes; Cysteine; Disease Models, Animal; Eosinophils; Goblet Cells; Hepatocyte Nuclear Factor 3-beta; Inflammation Mediators; Leukotriene Antagonists; Leukotrienes; Metaplasia; Mice; Mice, Knockout; Mice, Transgenic; Pneumonia; Quinolines; Signal Transduction; Sulfides; Th2 Cells | 2013 |
Antidepressant medication dispensing among montelukast initiators.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Antidepressive Agents; Asthma; Cyclopropanes; Depression; Female; Humans; Male; Quinolines; Sulfides; Young Adult | 2013 |
Anaphylaxislike cholinergic urticaria.
Topics: Acetates; Anaphylaxis; Cyclopropanes; Diagnosis, Differential; Hot Temperature; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides; Urticaria; Young Adult | 2013 |
Protection of montelukast on OVA-induced eosinophilic gastroenteritis via modulating IL-5, eotaxin-1 and MBP expression.
Topics: Acetates; Animals; Chemokine CCL11; Cyclopropanes; Enteritis; Eosinophil Major Basic Protein; Eosinophilia; Gastritis; Gene Expression Regulation; Interleukin-5; Leukotriene Antagonists; Mice; Mice, Inbred BALB C; Ovalbumin; Quinolines; Sulfides | 2013 |
Determination of the enantiomeric purity of the antiasthmatic drug montelukast by means of 1H NMR spectroscopy.
Topics: Acetates; Anti-Asthmatic Agents; Cinchona Alkaloids; Cyclopropanes; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Naphthalenes; Quinolines; Solubility; Stereoisomerism; Sulfides; Water | 2013 |
Does desloratadine alter the serum levels of montelukast when administered in a fixed-dose combination?
Topics: Acetates; Adult; Biological Availability; Cross-Over Studies; Cyclopropanes; Drug Interactions; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Loratadine; Male; Prospective Studies; Quinolines; Sulfides; Young Adult | 2013 |
Histopathologic evaluation of anti-ulcerogenic effect of montelukast in indomethacin-induced experimental ulcer model.
Topics: Acetates; Animals; Anti-Ulcer Agents; Cyclopropanes; Disease Models, Animal; Famotidine; Gastric Mucosa; Indomethacin; Leukocyte Count; Leukotriene Antagonists; Male; Neutrophils; Quinolines; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Sulfides | 2013 |
Effect of a cysteinyl leukotriene receptor antagonist on experimental emphysema and asthma combined with emphysema.
Topics: Acetates; Animals; Asthma; Bronchoalveolar Lavage Fluid; Chemokines; Cyclopropanes; Cysteine; Female; Leukotriene Antagonists; Leukotrienes; Lung; Mice; Mice, Inbred BALB C; Pneumonia; Pulmonary Emphysema; Quinolines; Receptors, Leukotriene; Sulfides; Tumor Necrosis Factor-alpha | 2014 |
Montelukast prevents microparticle-induced inflammatory and functional alterations in human bronchial smooth muscle cells.
Topics: Acetates; Active Transport, Cell Nucleus; Anti-Asthmatic Agents; Bronchi; Cell Line; Cell-Derived Microparticles; Cells, Cultured; Cyclooxygenase 2; Cyclopropanes; Gene Expression Regulation; Humans; Interleukin-8; Monocytes; Myocytes, Smooth Muscle; NF-kappa B; Quinolines; Receptors, Adrenergic, beta; Signal Transduction; Sulfides | 2013 |
Effects of polymorphisms of the SLCO2B1 transporter gene on the pharmacokinetics of montelukast in humans.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Cyclopropanes; Humans; Leukotriene Antagonists; Male; Organic Anion Transporters; Polymorphism, Single Nucleotide; Quinolines; Sulfides; Young Adult | 2013 |
Hallucination development with montelukast in a child with asthma: case presentation.
Topics: Acetates; Adolescent; Adult; Asthma; Cyclopropanes; Hallucinations; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides | 2013 |
Restoration of the normal Clara cell phenotype after chronic allergic inflammation.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchi; Budesonide; Chronic Disease; Cyclopropanes; Cytochrome P-450 CYP2E1; Disease Models, Animal; Epithelium; Female; Mice; Mice, Inbred BALB C; Ovalbumin; Phenotype; Pulmonary Surfactant-Associated Protein D; Quinolines; Sulfides; Uteroglobin | 2013 |
Montelukast is as effective as penicillin in treatment of acute otitis media: an experimental rat study.
Topics: Acetates; Animals; Cyclopropanes; Disease Models, Animal; Ear, Middle; Female; Mucous Membrane; Otitis Media; Penicillins; Quinolines; Rats; Rats, Wistar; Sulfides | 2013 |
Inhibitory effects of Montelukast on mediator release by nasal epithelial cells from asthmatic subjects with or without allergic rhinitis.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Cells, Cultured; Cyclopropanes; Cytokines; Epithelial Cells; Female; Humans; Male; Middle Aged; Nasal Mucosa; Quinolines; Rhinitis, Allergic; Rhinitis, Allergic, Perennial; Sulfides | 2013 |
High-performance liquid chromatographic method for the determination of dasatinib in rabbit plasma using fluorescence detection and its application to a pharmacokinetic study.
Topics: Acetates; Animals; Chromatography, High Pressure Liquid; Cyclopropanes; Dasatinib; Drug Stability; Limit of Detection; Linear Models; Male; Pyrimidines; Quinolines; Rabbits; Reproducibility of Results; Spectrometry, Fluorescence; Sulfides; Thiazoles | 2013 |
Effects of montelukast on subepithelial/peribronchial fibrosis in a murine model of ovalbumin induced chronic asthma.
Topics: Acetates; Allergens; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Cyclopropanes; Cytokines; Disease Models, Animal; Female; Immunoglobulin E; Leukotriene Antagonists; Lung; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Pulmonary Fibrosis; Quinolines; Smad3 Protein; Sulfides; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A | 2013 |
Montelukast sodium-induced hematuria: a case report and literature review of 19 cases in mainland China.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cyclopropanes; Female; Hematuria; Humans; Infant; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Sulfides | 2013 |
Antileukotriene reverts the early effects of inflammatory response of distal parenchyma in experimental chronic allergic inflammation.
Topics: Acetates; Administration, Inhalation; Animals; Chronic Disease; Cyclopropanes; Dexamethasone; Disease Models, Animal; Guinea Pigs; Hypersensitivity; Inflammation; Leukotriene Antagonists; Lung; Ovalbumin; Quinolines; Sulfides | 2013 |
Anti-inflammatory Montelukast prevents toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin: Oxidative stress, histological alterations in liver, and serum cytokine levels.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Catalase; Cyclopropanes; Female; Glutathione; Interleukin-1beta; Liver; Oxidative Stress; Polychlorinated Dibenzodioxins; Quinolines; Rats; Rats, Wistar; Sulfides; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha | 2016 |
Osmotically controlled pulsatile release capsule of montelukast sodium for chronotherapy: statistical optimization, in vitro and in vivo evaluation.
Topics: Acetates; Animals; Capsules; Chronotherapy; Cyclopropanes; Delayed-Action Preparations; Drug Evaluation, Preclinical; Intestinal Absorption; Osmosis; Quinolines; Rabbits; Sulfides | 2014 |
Effect of concomitant use of montelukast and efavirenz on neuropsychiatric adverse events.
Topics: Acetates; Adult; Alkynes; Anti-Asthmatic Agents; Anti-HIV Agents; Asthma; Benzoxazines; Cyclopropanes; Drug Interactions; Female; HIV Infections; Humans; Neurotoxicity Syndromes; Quinolines; Sulfides | 2014 |
Presentation of untreated systemic mastocytosis as recurrent, pulseless-electrical-activity cardiac arrests resistant to cardiac pacemaker.
Topics: Acetates; Aged, 80 and over; Aspirin; Cromolyn Sodium; Cyclopropanes; Death, Sudden, Cardiac; Drug Therapy, Combination; Electrocardiography; Female; Heart Rate; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Interleukin-2 Receptor alpha Subunit; Mast Cells; Mastocytosis, Systemic; Methylhistamines; Mutation; Pacemaker, Artificial; Quinolines; Recurrence; Stem Cell Factor; Sulfides; Tryptases | 2014 |
Potentiation of indomethacin-induced anti-inflammatory response by montelukast in formalin-induced inflammation in rats.
Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclopropanes; Dose-Response Relationship, Drug; Drug Synergism; Formaldehyde; Indomethacin; Inflammation; Male; Quinolines; Rats; Rats, Wistar; Sulfides | 2013 |
Montelukast: a novel therapeutic option in eosinophilic peritonitis.
Topics: Acetates; Adolescent; Cyclopropanes; Eosinophilia; Female; Humans; Leukotriene Antagonists; Peritoneal Dialysis; Peritonitis; Quinolines; Sulfides | 2014 |
The effect of montelukast and antiadhesion barrier solution on the capsule formation after insertion of silicone implants in a white rat model.
Topics: Acetates; Animals; Breast Implants; Collagen; Cyclopropanes; Immunohistochemistry; Postoperative Complications; Quinolines; Rats; Rats, Sprague-Dawley; Silicones; Solutions; Sulfides; Transforming Growth Factor beta | 2013 |
Montelukast prevents ischaemia/reperfusion-induced ovarian damage in rats.
Topics: Acetates; Animals; Caspase 3; Cyclopropanes; Female; Glutathione; Leukotriene Antagonists; Lipid Peroxidation; Malondialdehyde; Ovary; Pneumoperitoneum, Artificial; Quinolines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sulfides | 2014 |
Renoprotective effects of montelukast, a cysteinyl leukotriene receptor antagonist, against methotrexate-induced kidney damage in rats.
Topics: Acetates; Animals; Antimetabolites, Antineoplastic; Cyclopropanes; Glutathione; Kidney; Kidney Diseases; Leukotriene Antagonists; Male; Malondialdehyde; Methotrexate; NF-kappa B; Peroxidase; Protective Agents; Quinolines; Rats; Rats, Wistar; Sulfides; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2014 |
Montelukast and irbesartan ameliorate metabolic and hepatic disorders in fructose-induced metabolic syndrome in rats.
Topics: Acetates; Alanine Transaminase; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Blood Glucose; Caspase 3; Cyclopropanes; Fructose; Insulin; Irbesartan; Leukotriene Antagonists; Lipids; Liver; Liver Diseases; Male; Metabolic Syndrome; Quinolines; Rats; Rats, Wistar; Sulfides; Tetrazoles | 2014 |
Immune reconstitution inflammatory syndrome Kaposi sarcoma in the liver manifesting as acute obstructive hepatitis: another potential role for montelukast?
Topics: Acetates; Anti-Retroviral Agents; Antineoplastic Agents; Biopsy; CD4 Lymphocyte Count; Cyclopropanes; HIV Infections; Humans; Immune Reconstitution Inflammatory Syndrome; Jaundice, Obstructive; Leukotriene Antagonists; Liver; Liver Function Tests; Male; Middle Aged; Quinolines; Sarcoma, Kaposi; Skin Neoplasms; Sulfides; Treatment Outcome; Viral Load | 2013 |
Montelukast targeting the cysteinyl leukotriene receptor 1 ameliorates Aβ1-42-induced memory impairment and neuroinflammatory and apoptotic responses in mice.
Topics: Acetates; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Caspase 3; Cerebral Cortex; Cyclopropanes; Cytokines; Hippocampus; Leukotriene Antagonists; Male; Maze Learning; Memory Disorders; Mice; Mice, Inbred ICR; Neuroprotective Agents; NF-kappa B; Nootropic Agents; Peptide Fragments; Proto-Oncogene Proteins c-bcl-2; Quinolines; Receptors, Leukotriene; Sulfides | 2014 |
Postinfectious cough and pertussis in primary care.
Topics: Acetates; Cough; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Quinolines; Respiratory Tract Infections; Sulfides | 2014 |
Development of an LC-tandem mass spectrometry method for the separation of montelukast and its application to a pharmacokinetic study in humans.
Topics: Acetates; Adult; Chromatography, Liquid; Cyclopropanes; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides; Tandem Mass Spectrometry | 2014 |
Preparation, characterization and pulmonary pharmacokinetics of xyloglucan microspheres as dry powder inhalation.
Topics: Acetates; Administration, Inhalation; Animals; Calorimetry, Differential Scanning; Cyclopropanes; Glucans; Lung; Male; Microscopy, Electron, Scanning; Microspheres; Powders; Quinolines; Rats; Rats, Wistar; Sulfides; Xylans | 2014 |
Case study 4. Predicting the drug interaction potential for inhibition of CYP2C8 by montelukast.
Topics: Acetates; Aryl Hydrocarbon Hydroxylases; Cyclopropanes; Cytochrome P-450 CYP2C8; Drug Interactions; Enzyme Assays; Enzyme Inhibitors; Hepatocytes; Humans; Intracellular Space; Quinolines; Rosiglitazone; Sulfides; Thiazolidinediones | 2014 |
Classification and pharmacological treatment of preschool wheezing: changes since 2008.
Topics: Acetates; Administration, Oral; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Biomarkers; Child; Child, Preschool; Cyclopropanes; Glucocorticoids; Humans; International Cooperation; Practice Guidelines as Topic; Pulmonary Medicine; Quinolines; Respiratory Sounds; Sulfides | 2014 |
Low-level environmental tobacco smoke exposure and inflammatory biomarkers in children with asthma.
Topics: Acetates; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Child; Cohort Studies; Cotinine; Cyclopropanes; Environmental Monitoring; Female; Follow-Up Studies; Humans; Inflammation Mediators; Leukotriene E4; Male; Prospective Studies; Quinolines; Risk Assessment; Severity of Illness Index; Spirometry; Sulfides; Tobacco Smoke Pollution; Treatment Outcome | 2014 |
Biodegradable injectable in situ implants and microparticles for sustained release of montelukast: in vitro release, pharmacokinetics, and stability.
Topics: Absorbable Implants; Acetates; Animals; Chemistry, Pharmaceutical; Cyclopropanes; Dimethyl Sulfoxide; Drug Implants; Drug Stability; Injections, Intramuscular; Lactic Acid; Leukotriene Antagonists; Male; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Pyrrolidinones; Quinolines; Rats, Sprague-Dawley; Solubility; Solvents; Sulfides; Technology, Pharmaceutical; Temperature; Triacetin | 2014 |
Drugs to avoid during pregnancy: omalizumab and montelukast, too many uncertainties.
Topics: Acetates; Anti-Asthmatic Agents; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal, Humanized; Asthma; Cyclopropanes; Female; Humans; Omalizumab; Pregnancy; Pregnancy Complications; Quinolines; Sulfides | 2014 |
Montelukast attenuates neuropathic pain through inhibiting p38 mitogen-activated protein kinase and nuclear factor-kappa B in a rat model of chronic constriction injury.
Topics: Acetates; Animals; Astrocytes; Blotting, Western; Chronic Disease; Constriction, Pathologic; Cyclopropanes; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Hot Temperature; Interleukins; Leukotriene Antagonists; Male; Microglia; Neuralgia; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Physical Stimulation; Protein Kinase Inhibitors; Quinolines; Rats; Rats, Sprague-Dawley; Spinal Cord; Sulfides; Tumor Necrosis Factor-alpha | 2014 |
Leukotriene receptor antagonist as a novel tocolytic in an in vitro model of human uterine contractility.
Topics: Acetates; Adult; Area Under Curve; Calcium; Cyclopropanes; Extraembryonic Membranes; Female; Humans; Inhibitory Concentration 50; Leukotriene Antagonists; Leukotriene D4; Muscle Contraction; Myometrium; Nifedipine; Placenta; Pregnancy; Quinolines; Receptors, Leukotriene; Sulfides; Tissue Culture Techniques; Tocolytic Agents; Young Adult | 2014 |
Flushing, fatigue, and recurrent anaphylaxis: a delayed diagnosis of mastocytosis.
Topics: Acetates; Adult; Anaphylaxis; Cyclopropanes; Delayed Diagnosis; Drug Therapy, Combination; Epinephrine; Fatigue; Flushing; Histamine Antagonists; Humans; Leukotriene Antagonists; Loratadine; Male; Mastocytosis; Quinolines; Ranitidine; Recurrence; Sulfides | 2014 |
IL-33 enhanced the proliferation and constitutive production of IL-13 and IL-5 by fibrocytes.
Topics: Acetates; Actins; Cell Proliferation; Cells, Cultured; Cyclopropanes; Dexamethasone; Humans; Interleukin-1 Receptor-Like 1 Protein; Interleukins; Leukocytes, Mononuclear; Quinolines; Receptors, Cell Surface; Sulfides | 2014 |
Montelukast photodegradation: elucidation of Ф-order kinetics, determination of quantum yields and application to actinometry.
Topics: Acetates; Cyclopropanes; Drug Stability; Ethanol; Kinetics; Light; Models, Chemical; Molecular Structure; Photochemistry; Quantum Theory; Quinolines; Solutions; Spectrophotometry; Stereoisomerism; Sulfides | 2014 |
Montelukast suppresses epithelial to mesenchymal transition of bronchial epithelial cells induced by eosinophils.
Topics: Acetates; Airway Remodeling; Asthma; Bronchi; Cell Line, Tumor; Coculture Techniques; Collagen Type I; Cyclopropanes; Cysteine; Eosinophils; Epithelial-Mesenchymal Transition; Humans; Leukotriene Antagonists; Leukotrienes; Phosphorylation; Quinolines; Respiratory Mucosa; Smad3 Protein; Sulfides; Transforming Growth Factor beta1; Vimentin | 2014 |
Impact of a prior authorization policy for montelukast on clinical outcomes for asthma and allergic rhinitis among children and adolescents in a state Medicaid program.
Topics: Acetates; Adolescent; Age Factors; Anti-Allergic Agents; Anti-Asthmatic Agents; Anti-Bacterial Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Drug Utilization Review; Emergency Medical Services; Female; Humans; Infant; Infant, Newborn; Insurance Coverage; Insurance, Pharmaceutical Services; Linear Models; Logistic Models; Male; Medicaid; Odds Ratio; Office Visits; Policy Making; Program Evaluation; Quinolines; Retrospective Studies; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal; State Health Plans; Sulfides; Time Factors; Treatment Outcome; United States | 2014 |
Montelukast-loaded nanostructured lipid carriers: part I oral bioavailability improvement.
Topics: Acetates; Animals; Area Under Curve; Asthma; Calorimetry, Differential Scanning; Chromatography, High Pressure Liquid; Cyclopropanes; Drug Carriers; Lipids; Male; Microscopy, Electron, Transmission; Nanoparticles; Nanostructures; Particle Size; Quinolines; Rats; Rats, Wistar; Solubility; Spectroscopy, Fourier Transform Infrared; Sulfides; Surface-Active Agents; X-Ray Diffraction | 2014 |
Montelukast rescues primary neurons against Aβ1-42-induced toxicity through inhibiting CysLT1R-mediated NF-κB signaling.
Topics: Acetates; Amyloid beta-Peptides; Animals; Caspase 3; Cyclopropanes; Cytokines; Enzyme Activation; Inflammation Mediators; Leukotriene Antagonists; Mice; Mice, Inbred ICR; Neurons; NF-kappa B; Peptide Fragments; Proto-Oncogene Proteins c-bcl-2; Quinolines; Receptors, Leukotriene; Signal Transduction; Sulfides | 2014 |
[A case of neuroendocrine cell hyperplasia of infancy (NEHI)].
Topics: Acetates; Cyclopropanes; Diagnosis, Differential; Female; Follow-Up Studies; Humans; Hyperplasia; Infant; Lung; Lung Diseases, Interstitial; Methylprednisolone; Neuroendocrine Cells; Quinolines; Sulfides; Tomography, X-Ray Computed | 2014 |
[Onset feature and efficacy of early interventional treatment of Artemisia pollinosis].
Topics: Acetates; Adolescent; Adult; Age of Onset; Allergens; Artemisia; Child; China; Cyclopropanes; Female; Humans; Male; Middle Aged; Mometasone Furoate; Pollen; Pregnadienediols; Quinolines; Rhinitis, Allergic, Seasonal; Seasons; Sulfides; Treatment Outcome; Young Adult | 2014 |
Aerosolized montelukast polymeric particles-an alternative to oral montelukast-alleviate symptoms of asthma in a rodent model.
Topics: Acetates; Aerosols; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cyclopropanes; Cysteine; Disease Models, Animal; Inflammation; L-Lactate Dehydrogenase; Lactic Acid; Leukotrienes; Lung; Ovalbumin; Peroxidase; Polyesters; Polymers; Quinolines; Rats; Rats, Sprague-Dawley; Sulfides | 2014 |
Role of cysteinyl leukotriene signaling in a mouse model of noise-induced cochlear injury.
Topics: Acetates; Animals; Cochlea; Cyclopropanes; Cysteine; Disease Models, Animal; Gene Expression Profiling; Leukotriene Antagonists; Leukotrienes; Matrix Metalloproteinase 3; Mice; Noise; Quinolines; Receptors, Leukotriene; Signal Transduction; Sulfides; Wounds and Injuries | 2014 |
Dose escalation of montelukast in the treatment of nine patients with nasal polyposis: an open pilot study: our experience.
Topics: Acetates; Adult; Cyclopropanes; Endoscopy; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Nasal Polyps; Pilot Projects; Quinolines; Sulfides | 2014 |
Effects of montelukast and methylprednisolone on experimental spinal cord injury in rats.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Creatine Kinase; Cyclopropanes; Glutathione Peroxidase; L-Lactate Dehydrogenase; Laminectomy; Male; Malondialdehyde; Methylprednisolone; Neuroprotective Agents; Nitric Oxide; Quinolines; Rats, Wistar; Spinal Cord Injuries; Sulfides; Superoxide Dismutase | 2014 |
[Antioxidative effects of cysteinyl leukotriene receptor antagonists montelukast and HAMI 3379 on ischemic injury in rat cortical neurons in vitro].
Topics: Acetates; Animals; Antioxidants; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Cyclohexanecarboxylic Acids; Cyclopropanes; Leukotriene Antagonists; Neurons; Phthalic Acids; Quinolines; Rats; Reactive Oxygen Species; Sulfides | 2014 |
No FDA approval for over-the-counter use of montelukast.
Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Child; Cyclopropanes; Drug Approval; Humans; Nonprescription Drugs; Quinolines; Sulfides; United States; United States Food and Drug Administration; Young Adult | 2014 |
Management of acute loss of asthma control in the yellow zone: a practice parameter.
Topics: Acetates; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Asthma; Bronchodilator Agents; Cyclopropanes; Humans; Leukotriene Antagonists; Nebulizers and Vaporizers; Quinolines; Respiratory Tract Infections; Self Care; Sulfides | 2014 |
An evaluation of prophylactic treatments to prevent post traumatic joint stiffness.
Topics: Acetates; Administration, Oral; Animals; Colforsin; Contracture; Cyclopropanes; Fibrosis; Hindlimb; Injections, Intra-Articular; Joint Capsule; Joints; Knee Injuries; Male; Quinolines; Range of Motion, Articular; Rats; Rats, Sprague-Dawley; Sulfides; Triamcinolone | 2014 |
Montelukast-loaded nanostructured lipid carriers: part II pulmonary drug delivery and in vitro-in vivo aerosol performance.
Topics: Acetates; Administration, Inhalation; Aerosols; Animals; Cell Line, Tumor; Cyclopropanes; Diglycerides; Drug Delivery Systems; Dry Powder Inhalers; Humans; Lipids; Lung; Male; Nanoparticles; Particle Size; Polymers; Powders; Propylene Glycols; Quinolines; Rats; Rats, Wistar; Sulfides | 2014 |
An open-label study examining the effect of pharmacological treatment on mannitol- and exercise-induced airway hyperresponsiveness in asthmatic children and adolescents with exercise-induced bronchoconstriction.
Topics: Acetates; Administration, Inhalation; Adolescent; Anti-Asthmatic Agents; Asthma, Exercise-Induced; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents; Budesonide; Child; Cyclopropanes; Drug Administration Schedule; Exercise Test; Female; Forced Expiratory Volume; Humans; Male; Mannitol; Quinolines; Sulfides; Treatment Outcome; Young Adult | 2014 |
Cysteinyl leukotriene receptor (CysLT) antagonists decrease pentylenetetrazol-induced seizures and blood-brain barrier dysfunction.
Topics: Acetates; Animals; Anticonvulsants; Blood-Brain Barrier; Brain; Capillary Permeability; Chromones; Cyclopropanes; Dose-Response Relationship, Drug; Immunoglobulin G; Leukocyte Common Antigens; Leukocytes; Leukotriene Antagonists; Leukotriene D4; Male; Mice; Neuroprotective Agents; Pentylenetetrazole; Quinolines; Receptors, Leukotriene; Seizures; SRS-A; Sulfides | 2014 |
Improvement of sinus disease in cystic fibrosis with ivacaftor therapy.
Topics: Acetates; Adult; Aminophenols; Androstadienes; Anti-Allergic Agents; Cyclopropanes; Cystic Fibrosis; Female; Fluticasone; Humans; Leukotriene Antagonists; Paranasal Sinus Diseases; Quinolines; Quinolones; Rhinitis, Allergic, Perennial; Sulfides; Treatment Outcome; Young Adult | 2014 |
Simultaneous determination of desloratadine and montelukast sodium using second-derivative synchronous fluorescence spectrometry enhanced by an organized medium with applications to tablets and human plasma.
Topics: Acetates; Calibration; Carboxymethylcellulose Sodium; Chemistry, Pharmaceutical; Cyclopropanes; Humans; Hydrogen-Ion Concentration; Limit of Detection; Loratadine; Quinolines; Reproducibility of Results; Sensitivity and Specificity; Solvents; Spectrometry, Fluorescence; Sulfides; Tablets | 2015 |
Wheezing in young children: WAITing for pharmacogenomics?
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Female; Humans; Male; Quinolines; Respiratory Sounds; Sulfides | 2014 |
Montelukast reduces sepsis-induced lung and renal injury in rats.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Antioxidants; Body Weight; Cyclopropanes; Kidney; Lipopolysaccharides; Lung; Male; Oxidative Stress; Quinolines; Random Allocation; Rats, Sprague-Dawley; Sulfides; Systemic Inflammatory Response Syndrome | 2014 |
Montelukast--place in therapy.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Quinolines; Rhinitis, Allergic; Rhinitis, Allergic, Perennial; Sulfides | 2014 |
Montelukast, a cysteinyl leukotriene receptor-1 antagonist protects against hippocampal injury induced by transient global cerebral ischemia and reperfusion in rats.
Topics: Acetates; Animals; Apoptosis Regulatory Proteins; Biomarkers; Cerebral Infarction; Cyclopropanes; Hippocampus; Inflammation Mediators; Ischemic Attack, Transient; Leukotriene Antagonists; Male; Neurotransmitter Agents; Oxidative Stress; Quinolines; Rats; Rats, Wistar; Receptors, Leukotriene; Reperfusion Injury; Sulfides | 2015 |
Simulation of in vitro dissolution behavior using DDDPlus™.
Topics: Acetates; Algorithms; Anti-Asthmatic Agents; Body Fluids; Computer Simulation; Cyclopropanes; Drug Liberation; Glyburide; Hypoglycemic Agents; Models, Chemical; Quinolines; Software; Sulfides | 2015 |
Is montelukast effective in regression of endometrial implants in an experimentally induced endometriosis model in rats?
Topics: Acetates; Animals; Anti-Inflammatory Agents; Cyclopropanes; Disease Models, Animal; Endometriosis; Endometrium; Female; Leuprolide; Matrix Metalloproteinase 2; Quinolines; Rats; Rats, Wistar; Sulfides; Treatment Outcome; Vascular Endothelial Growth Factor A | 2015 |
Protective effects of montelukast and Hypericum perforatum against intestinal ischemia-reperfusion injury in hamsters.
Topics: Acetates; Animals; Cricetinae; Cyclopropanes; Disease Models, Animal; Glutathione; Hypericum; Intestines; Malondialdehyde; Mesenteric Artery, Superior; Mesocricetus; Plant Extracts; Protective Agents; Quinolines; Random Allocation; Reperfusion Injury; Sulfides | 2014 |
Comparison of the efficacy of prednisolone, montelukast, and omalizumab in an experimental allergic rhinitis model.
Topics: Acetates; Animals; Anti-Allergic Agents; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal, Humanized; Cyclopropanes; Disease Models, Animal; Lung; Mast Cells; Nasal Mucosa; Omalizumab; Prednisolone; Quinolines; Random Allocation; Rats; Rats, Sprague-Dawley; Rhinitis, Allergic; Sneezing; Sulfides | 2014 |
Cysteinyl 1 receptor antagonist montelukast, does not prevent peritoneal membrane damage in experimental chronic peritoneal dialysis model in rats.
Topics: Acetates; Animals; Cyclopropanes; Cytokines; Fibrosis; Kidney Failure, Chronic; Leukotriene Antagonists; Male; Membranes; Peritoneal Dialysis, Continuous Ambulatory; Peritoneum; Quinolines; Rats; Rats, Wistar; Sulfides; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A | 2014 |
Comparison of montelukast and cabergoline for prevention of ovarian hyperstimulation syndrome: in an experimental rat model.
Topics: Acetates; Animals; Ascitic Fluid; Body Weight; Cabergoline; Capillary Permeability; Chorionic Gonadotropin; Cyclopropanes; Dopamine Agonists; Ergolines; Female; Gonadotropins, Equine; Horses; Humans; Immunohistochemistry; Leukotriene Antagonists; Organ Size; Ovarian Hyperstimulation Syndrome; Ovary; Ovulation Induction; Quinolines; Rats; Rats, Wistar; Reproductive Control Agents; Sulfides; Vascular Endothelial Growth Factor A | 2015 |
Exploring the possible association between montelukast and neuropsychiatric events among children with asthma: a matched nested case-control study.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Case-Control Studies; Child; Cyclopropanes; Female; Humans; Logistic Models; Male; Mental Disorders; Quinolines; Sulfides | 2015 |
Effects of interleukin-13 and montelukast on the expression of zonula occludens-1 in human podocytes.
Topics: Acetates; Blotting, Western; Cyclopropanes; Dose-Response Relationship, Drug; Humans; Interleukin-13; Leukotriene Antagonists; Microscopy, Confocal; Podocytes; Proteinuria; Quinolines; Sulfides; Tight Junctions; Zonula Occludens-1 Protein | 2015 |
Montelukast potentiates the anticonvulsant effect of phenobarbital in mice: an isobolographic analysis.
Topics: Acetates; Animals; Anticonvulsants; Convulsants; Cyclopropanes; Dose-Response Relationship, Drug; Drug Synergism; Electroencephalography; Female; Leukotriene Antagonists; Mice; Motor Activity; Pentylenetetrazole; Phenobarbital; Quinolines; Seizures; Sulfides | 2015 |
Leukotriene C4 induces bronchoconstriction and airway vascular hyperpermeability via the cysteinyl leukotriene receptor 2 in S-hexyl glutathione-treated guinea pigs.
Topics: Acetates; Animals; Bronchoconstriction; Calcium; Capillary Permeability; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Glutathione; Guinea Pigs; Leukotriene C4; Leukotriene D4; Lung; Male; Quinolines; Receptors, Leukotriene; Sulfides; Triazoles | 2015 |
Do Montelukast Sodium and N-Acetylcysteine Have a Nephroprotective Effect on Unilateral Ureteral Obstruction? A Placebo Controlled Trial in a Rat Model.
Topics: Acetates; Acetylcysteine; Animals; Cyclopropanes; Disease Models, Animal; Kidney Diseases; Male; Placebos; Quinolines; Randomized Controlled Trials as Topic; Rats; Rats, Wistar; Sulfides; Ureteral Obstruction | 2015 |
Montelukast inhibits pentylenetetrazol-induced seizures in rats.
Topics: Acetates; Action Potentials; Animals; Brain; Cyclopropanes; Electroencephalography; Male; Malondialdehyde; Pentylenetetrazole; Quinolines; Rats, Sprague-Dawley; Seizures; Sulfides; Superoxide Dismutase; Time Factors | 2015 |
An enantioselective formal synthesis of montelukast sodium.
Topics: Acetates; Anti-Asthmatic Agents; Catalysis; Coordination Complexes; Cyclopropanes; Hydrogenation; Molecular Structure; Quinolines; Ruthenium; Sodium; Stereoisomerism; Sulfides | 2015 |
Co-processed chitin-mannitol as a new excipient for Oro-dispersible tablets.
Topics: Acetates; Administration, Oral; Anti-Asthmatic Agents; Antiemetics; Calorimetry, Differential Scanning; Chemical Phenomena; Chitin; Cyclopropanes; Domperidone; Drug Compounding; Drug Delivery Systems; Drug Liberation; Excipients; Humans; Mannitol; Microscopy, Electron, Scanning; Particle Size; Powder Diffraction; Quinolines; Spectroscopy, Fourier Transform Infrared; Sulfides; Tablets; Water | 2015 |
Antiallergic effect of piperine on ovalbumin-induced allergic rhinitis in mice.
Topics: Acetates; Alkaloids; Animals; Anti-Allergic Agents; Benzodioxoles; Biomarkers; Cell Degranulation; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Eosinophils; Histamine; Immunoglobulin E; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Mast Cells; Nitric Oxide; Ovalbumin; Piperidines; Polyunsaturated Alkamides; Quinolines; Rhinitis, Allergic; Spleen; Sulfides; Time Factors | 2015 |
Development of montelukast sodium loaded niosomal carriers by film hydration technique.
Topics: Acetates; Chemistry, Pharmaceutical; Cyclopropanes; Drug Delivery Systems; Drug Liberation; Drug Stability; Excipients; Hexoses; Humans; Liposomes; Microscopy, Electron, Transmission; Models, Theoretical; Particle Size; Quinolines; Sulfides; Surface-Active Agents; Transport Vesicles; Viscosity | 2015 |
Effectiveness of Montelukast on asthma control in infants: methodology of a French claims data study.
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Cohort Studies; Cyclopropanes; Databases, Factual; Female; France; Humans; Infant; Male; Pilot Projects; Quinolines; Sulfides; Treatment Outcome | 2015 |
Treatment of solar urticaria using antihistamine and leukotriene receptor antagonist combinations tailored to disease severity.
Topics: Acetates; Adolescent; Adult; Cetirizine; Child; Child, Preschool; Cyclopropanes; Drug Therapy, Combination; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Photosensitivity Disorders; Quinolines; Remission Induction; Remission, Spontaneous; Severity of Illness Index; Sulfides; Sunlight; Terfenadine; Ultraviolet Rays; Urticaria; Young Adult | 2015 |
Genome-Wide Association Study Identifies Novel Pharmacogenomic Loci For Therapeutic Response to Montelukast in Asthma.
Topics: Acetates; Adult; Asthma; Cyclopropanes; Female; Genetic Loci; Genome-Wide Association Study; Humans; Lung; Male; Pharmacogenetics; Polymorphism, Single Nucleotide; Quinolines; Sulfides; Treatment Outcome | 2015 |
Montelukast attenuates lipopolysaccharide-induced cardiac injury in rats.
Topics: Acetates; Alkaline Phosphatase; Animals; Blood Proteins; Body Weight; Creatine Kinase, MB Form; Cyclopropanes; Dexamethasone; Glutathione; Heart; Heart Diseases; L-Lactate Dehydrogenase; Lipopolysaccharides; Male; Malondialdehyde; Organ Size; Quinolines; Rats; Rats, Sprague-Dawley; Sulfides; Tumor Necrosis Factor-alpha | 2016 |
Infection as a Trigger for Portal Hypertension.
Topics: Acetates; Animals; Anti-Infective Agents; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Bacterial Translocation; Cyclopropanes; Endothelial Cells; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Gram-Negative Bacterial Infections; Hepatic Stellate Cells; Humans; Hypertension, Portal; Kupffer Cells; Leukotriene Antagonists; Leukotrienes; Liver; Liver Cirrhosis; Portal Pressure; Quinolines; Rats; Receptors, Cell Surface; Rifamycins; Rifaximin; Sulfides; Thromboxane A2; Vasoconstriction | 2015 |
Determination of the impurities in drug products containing montelukast and in silico/in vitro genotoxicological assessments of sulfoxide impurity.
Topics: Acetates; Adult; Animals; Anti-Asthmatic Agents; Cells, Cultured; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Chromosome Aberrations; Computer Simulation; Cyclopropanes; Dose-Response Relationship, Drug; Drug Contamination; Female; Gene Expression Regulation, Bacterial; Humans; Leukotriene Antagonists; Lymphocytes; Male; Mitosis; Mitotic Index; Mutagenicity Tests; Mutation; Quinolines; Rats, Sprague-Dawley; Risk Assessment; Sulfides; Sulfoxides; Turkey | 2015 |
Effect of montelukast monotherapy on oxidative stress parameters and DNA damage in children with asthma.
Topics: Acetates; Anti-Asthmatic Agents; Antioxidants; Asthma; Case-Control Studies; Child; Child, Preschool; Cyclopropanes; DNA Damage; Female; Humans; Male; Oxidative Stress; Quinolines; Sulfides | 2015 |
Effect of montelukast on the expression of interleukin-18, telomerase reverse transcriptase, and Bcl-2 in the brain tissue of neonatal rats with hypoxic-ischemic brain damage.
Topics: Acetates; Animals; Animals, Newborn; Case-Control Studies; Cyclopropanes; Disease Models, Animal; Hypoxia-Ischemia, Brain; Immunohistochemistry; Interleukin-18; Proto-Oncogene Proteins c-bcl-2; Quinolines; Rats; Sulfides; Telomerase | 2015 |
In Vitro Metabolism of Montelukast by Cytochrome P450s and UDP-Glucuronosyltransferases.
Topics: Acetates; Cyclopropanes; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Glucuronosyltransferase; Humans; Microsomes, Liver; Quinolines; Sulfides; Tandem Mass Spectrometry | 2015 |
Effect of Montelukast on Spinal Cord Ischemia- Reperfusion Injury.
Topics: Acetates; Animals; Cyclopropanes; Interleukin-6; Leukotriene Antagonists; Male; Neuroprotective Agents; Paraplegia; Peroxidase; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Leukotriene; Reperfusion Injury; Spinal Cord Ischemia; Sulfides | 2015 |
Is montelukast as effective as N-acetylcysteine in hepatic injury due to acetaminophen intoxication in rats?
Topics: Acetaminophen; Acetates; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Cyclopropanes; Cytochrome P-450 CYP1A2 Inducers; Disease Models, Animal; Free Radical Scavengers; Male; Quinolines; Rats; Rats, Wistar; Sulfides | 2016 |
Can a single dose response predict the effect of montelukast on exercise-induced bronchoconstriction?
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Bronchoconstriction; Child; Cyclopropanes; Exercise Test; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Predictive Value of Tests; Prospective Studies; Quinolines; Sulfides; Treatment Outcome | 2016 |
Montelukast is effective in preventing of ovarian hyperstimulation syndrome; an experimental study.
Topics: Acetates; Animals; Cabergoline; Chorionic Gonadotropin; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Ergolines; Female; Ovarian Hyperstimulation Syndrome; Ovary; Quinolines; Random Allocation; Rats; Rats, Wistar; Sulfides | 2015 |
The protective role of montelukast against intestinal ischemia-reperfusion injury in rats.
Topics: Acetates; Acute-Phase Proteins; Alanine Transaminase; Animals; Aspartate Aminotransferases; Caspase 8; Caspase 9; Cyclopropanes; Interleukin-6; Intestinal Mucosa; Kidney; Lipocalin-2; Lipocalins; Liver; Male; Protective Agents; Proto-Oncogene Proteins; Quinolines; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, Leukotriene; Reperfusion Injury; RNA, Messenger; Sulfides; Tumor Necrosis Factor-alpha | 2015 |
Role of cysteinyl leukotriene receptor-1 antagonists in treatment of experimentally induced mammary tumor: does montelukast modulate antitumor and immunosuppressant effects of doxorubicin?
Topics: Acetates; Animals; Antineoplastic Agents; Apoptosis; Cyclopropanes; Doxorubicin; Female; Immunoglobulin G; Immunosuppressive Agents; Leukotriene Antagonists; Mammary Neoplasms, Experimental; Mice; NF-kappa B; Quinolines; Receptors, Leukotriene; Sulfides; T-Lymphocytes; Tumor Necrosis Factor-alpha | 2015 |
Reversal in Cognition Impairments, Cholinergic Dysfunction, and Cerebral Oxidative Stress Through the Modulation of Ryanodine Receptors (RyRs) and Cysteinyl Leukotriene-1 (CysLT1) Receptors.
Topics: Acetates; Animals; Carotid Artery Diseases; Cerebral Cortex; Cholinergic Agents; Cognition Disorders; Cyclopropanes; Disease Models, Animal; Glutathione; Leukotriene Antagonists; Lipid Peroxidation; Male; Mice; Oxidative Stress; Oxidoreductases; Quinolines; Receptors, Leukotriene; Ruthenium Red; Ryanodine Receptor Calcium Release Channel; Sulfides; Time Factors | 2016 |
Prevention of Capsular Contracture Using Leukotriene Antagonists.
Topics: Acetates; Adolescent; Adult; Brazil; Breast Implants; Cohort Studies; Cyclopropanes; Female; Follow-Up Studies; Humans; Implant Capsular Contracture; Leukotriene Antagonists; Logistic Models; Mammaplasty; Middle Aged; Multivariate Analysis; Primary Prevention; Quinolines; Retrospective Studies; Risk Assessment; Sulfides; Treatment Outcome; Young Adult | 2015 |
Beliefs about medication predict the misattribution of a common symptom as a medication side effect--Evidence from an analogue online study.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Evidence-Based Medicine; Female; Health Knowledge, Attitudes, Practice; Humans; Male; Middle Aged; Perception; Quinolines; Sulfides; Surveys and Questionnaires | 2015 |
Toxicity of Carboxylic Acid-Containing Drugs: The Role of Acyl Migration and CoA Conjugation Investigated.
Topics: Acetates; Acyl Coenzyme A; Acylation; Carboxylic Acids; Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Cyclopropanes; Gemfibrozil; Humans; Mass Spectrometry; Microsomes, Liver; Molecular Structure; Quinolines; Sulfides; Tolmetin | 2015 |
Identification of putative substrates for cynomolgus monkey cytochrome P450 2C8 by substrate depletion assays with 22 human P450 substrates and inhibitors.
Topics: Acetates; Amodiaquine; Animals; Cyclopropanes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Macaca fascicularis; Pharmaceutical Preparations; Quercetin; Quinolines; Rosiglitazone; Species Specificity; Substrate Specificity; Sulfides; Thiazolidinediones | 2016 |
Psychiatric Disorders and Montelukast in Children: A Disproportionality Analysis of the VigiBase(®).
Topics: Acetates; Adolescent; Adverse Drug Reaction Reporting Systems; Age Factors; Anti-Asthmatic Agents; Bayes Theorem; Child; Child, Preschool; Cyclopropanes; Female; Humans; Infant; Male; Mental Disorders; Pharmacovigilance; Quinolines; Retrospective Studies; Suicide; Sulfides | 2016 |
Lipoxin Inhibits Fungal Uptake by Macrophages and Reduces the Severity of Acute Pulmonary Infection Caused by Paracoccidioides brasiliensis.
Topics: Acetates; Animals; Arachidonate 5-Lipoxygenase; Cyclopropanes; Dinoprostone; Inflammation Mediators; Leukotriene Antagonists; Leukotriene C4; Lipoxins; Macrophages, Alveolar; Male; Mice; Mice, 129 Strain; Mice, Inbred A; Mice, Knockout; Paracoccidioides; Paracoccidioidomycosis; Quinolines; Receptors, Leukotriene; Receptors, Pattern Recognition; Sulfides | 2015 |
[The effect of generic price competition on drug consumption and health insurance pharmaceutical expenditures in Hungary].
Topics: Acetates; Anti-Asthmatic Agents; Cyclopropanes; Drug Costs; Drugs, Generic; Economic Competition; Health Policy; Humans; Hungary; Insurance Coverage; Insurance, Pharmaceutical Services; National Health Programs; Quinolines; Sulfides | 2015 |
Formulation and evaluation of a montelukast sodium orally disintegrating tablet with a similar dissolution profile as the marketed product.
Topics: Acetates; Administration, Oral; Anti-Asthmatic Agents; Cyclopropanes; Drug Compounding; Drug Liberation; Hardness; Leukotriene Antagonists; Quinolines; Solubility; Sulfides; Tablets; Wettability | 2017 |
Plasma total thiol pool in children with asthma: Modulation during montelukast monotherapy.
Topics: Acetates; Antioxidants; Asthma; Child; Child, Preschool; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfhydryl Compounds; Sulfides | 2016 |
Montelukast versus Dexamethasone Treatment in a Guinea Pig Model of Chronic Pulmonary Neutrophilic Inflammation.
Topics: Acetates; Animals; Bronchoalveolar Lavage Fluid; Chronic Disease; Cyclopropanes; Dexamethasone; Disease Models, Animal; Glucocorticoids; Guinea Pigs; Histone Deacetylases; Inflammation; Leukocyte Count; Leukotriene Antagonists; Leukotriene B4; Lipopolysaccharides; Lung; Male; Malondialdehyde; Neutrophils; Pulmonary Disease, Chronic Obstructive; Quinolines; Respiratory Hypersensitivity; Sulfides; Tumor Necrosis Factor-alpha | 2016 |
Effectiveness of leukotriene receptor antagonism in the postoperative management of chronic rhinosinusitis.
Topics: Acetates; Adolescent; Adult; Aged; Asthma; Chronic Disease; Cyclopropanes; Eosinophils; Female; Follow-Up Studies; Humans; Leukotriene Antagonists; Male; Middle Aged; Postoperative Complications; Quinolines; Retrospective Studies; Rhinitis; Rhinoplasty; Sinusitis; Sulfides; Treatment Outcome; Young Adult | 2016 |
Montelukast reduces seizures in pentylenetetrazol-kindled mice.
Topics: Acetates; Animals; Anticonvulsants; Blotting, Western; Convulsants; Cyclopropanes; Kindling, Neurologic; Leukotriene Antagonists; Male; Mice; Pentylenetetrazole; Phenobarbital; Quinolines; Receptors, Leukotriene; Seizures; Sulfides; Time Factors; Treatment Outcome | 2016 |
Ageing: Restoration project.
Topics: Acetates; Aging; Alzheimer Disease; Animals; Anti-Asthmatic Agents; Cognition Disorders; Cyclopropanes; Estrogens; Female; Hippocampus; Humans; Inflammation Mediators; Leukotrienes; Macaca mulatta; Male; Mice; Neuronal Plasticity; Parkinson Disease; Plasma; Prefrontal Cortex; Quinolines; Rats; Rejuvenation; Sulfides; Synapses | 2016 |
Involvement of opioid receptors in the systemic and peripheral antinociceptive actions of montelukast in the animal models of pain.
Topics: Acetates; Acetic Acid; Analgesics; Animals; Behavior, Animal; Cyclopropanes; Disease Models, Animal; Drug Synergism; Formaldehyde; Male; Mice; Naloxone; Pain; Quinolines; Rats; Receptors, Opioid; Sulfides; Visceral Pain | 2016 |
Determination of Montelukast in Plasma Using β - Cyclodextrins Coated on CoFe2O4 Magnetic Nanoparticles in Luminol-H2O2 Chemiluminescence System Optimized by Doehlert Design.
Topics: Acetates; beta-Cyclodextrins; Blood Chemical Analysis; Cobalt; Cyclopropanes; Ferric Compounds; Humans; Hydrogen Peroxide; Luminescent Measurements; Luminol; Magnets; Nanoparticles; Quinolines; Sulfides | 2016 |
Novel montelukast sodium-loaded stable oral suspension bioequivalent to the commercial granules in rats.
Topics: Acetates; Administration, Oral; Animals; Anti-Asthmatic Agents; Cellulose; Cyclopropanes; Drug Stability; Excipients; Fumarates; Glycerol; Male; Quinolines; Rats, Sprague-Dawley; Solubility; Sulfides; Suspensions; Technology, Pharmaceutical; Therapeutic Equivalency | 2016 |
[POSSIBILITIES FOR THE USE OF THE ANTI-LEUKOTRIENE DRUG MONTELUKAST IN COMBINED THERAPY OF PATIENTS WITH BRONCHIAL ASTHMA AND COLD-INDUCED BRONCHIAL HYPERACTIVITY].
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Cold Temperature; Cyclopropanes; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Quinolines; Sulfides; Treatment Outcome; Young Adult | 2015 |
Chemical Genomics Identifies the PERK-Mediated Unfolded Protein Stress Response as a Cellular Target for Influenza Virus Inhibition.
Topics: Acetates; Cyclopropanes; eIF-2 Kinase; Humans; Influenza A virus; Influenza, Human; Phosphorylation; Quinolines; Sulfides; Unfolded Protein Response; Viral Proteins; Virus Replication | 2016 |
Predictors of asthma following severe respiratory syncytial virus (RSV) bronchiolitis in early childhood.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Bronchiolitis, Viral; Child; Child, Preschool; Cyclopropanes; Dander; Dogs; Europe; Female; Humans; Hypersensitivity; Hypersensitivity, Immediate; Infant; Interleukin-16; Interleukin-18; Interleukin-5; Longitudinal Studies; Male; Medical History Taking; Prevalence; Prospective Studies; Quinolines; Respiratory Rate; Respiratory Sounds; Respiratory Syncytial Virus Infections; Rhinitis, Allergic; Risk Factors; Severity of Illness Index; Sex Factors; Sulfides | 2016 |
Seizures as a rare but serious adverse effect of leukotriene receptor.
Topics: Acetates; Adolescent; Asthma; Child; Child, Preschool; Cyclopropanes; Epilepsy; Female; Humans; Leukotriene Antagonists; Male; Quinolines; Receptors, Leukotriene; Rhinitis, Allergic; Seizures; Sulfides; Withholding Treatment | 2016 |
Therapeutic effect of budesonide/formoterol, montelukast and N-acetylcysteine for bronchiolitis obliterans syndrome after hematopoietic stem cell transplantation.
Topics: Acetates; Acetylcysteine; Adrenergic beta-2 Receptor Agonists; Adult; Anti-Inflammatory Agents; Antioxidants; Bronchiolitis Obliterans; Bronchodilator Agents; Budesonide, Formoterol Fumarate Drug Combination; Cyclopropanes; Drug Therapy, Combination; Female; Forced Expiratory Volume; Glucocorticoids; Hematopoietic Stem Cell Transplantation; Humans; Leukotriene Antagonists; Lung; Male; Middle Aged; Quinolines; Recovery of Function; Retrospective Studies; Sulfides; Time Factors; Treatment Outcome; Vital Capacity | 2016 |
Inflammatory markers as exacerbation risk factors after asthma therapy switch from inhaled steroids to montelukast.
Topics: Acetates; Administration, Inhalation; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Child; Cyclopropanes; Eosinophils; Female; Follow-Up Studies; Glucocorticoids; Humans; Inflammation; Leukotriene Antagonists; Male; Nitric Oxide; Practice Guidelines as Topic; Prospective Studies; Quinolines; Risk Factors; Sputum; Sulfides | 2016 |
MONITORING THE EFFICACY OF MONTELUKAST USED IN CHILDREN WITH RISK OF ASTHMA.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Quinolines; Risk; Sulfides | 2016 |
Cysteinyl leukotriene receptor antagonist epigenetically modulates cytokine expression and maturation of human myeloid dendritic cells.
Topics: Acetates; Anti-Asthmatic Agents; Cyclopropanes; Cytokines; Dendritic Cells; Enzyme-Linked Immunosorbent Assay; Epigenesis, Genetic; Humans; Interleukin-10; Leukotriene Antagonists; Lipopolysaccharides; Poly I-C; Quinolines; Receptors, Leukotriene; Sulfides; Th1 Cells; Th2 Cells; Tumor Necrosis Factor-alpha | 2016 |
Effects of montelukast on M2-related cytokine and chemokine in M2 macrophages.
Topics: Acetates; Cell Survival; Chemokine CCL1; Chemokine CCL22; Chemokines; Cyclopropanes; Cytokines; Humans; Interleukin-10; Interleukin-4; Lipopolysaccharides; Macrophages; Monocytes; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Quinolines; Signal Transduction; Sulfides; THP-1 Cells | 2018 |
Effect of Traditional Chinese Medicine on Inflammatory Mediators in Pediatric Asthma.
Topics: Acetates; Albuterol; Asthma; Child, Preschool; Cyclopropanes; Enzyme-Linked Immunosorbent Assay; Female; Humans; Interleukin-10; Interleukin-17; Male; Matrix Metalloproteinase 9; Medicine, Chinese Traditional; Quinolines; Randomized Controlled Trials as Topic; Real-Time Polymerase Chain Reaction; RNA, Messenger; Single-Blind Method; Sulfides; Transforming Growth Factor beta1 | 2016 |
Electrosprayed Montelukast/poly (lactic-co-glycolic acid) particle based coating: A new therapeutic approach towards the prevention of in-stent restenosis.
Topics: Acetates; Calorimetry, Differential Scanning; Cell Count; Cell Movement; Cell Proliferation; Coated Materials, Biocompatible; Coronary Restenosis; Coronary Vessels; Cyclopropanes; Drug Liberation; Endothelial Cells; Flow Cytometry; Humans; Lactic Acid; Myocytes, Smooth Muscle; Phenotype; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Quinolines; Receptors, Leukotriene; Stents; Sulfides | 2016 |
Cytochrome P450 Oxidase 2C Inhibition Adds to ω-3 Long-Chain Polyunsaturated Fatty Acids Protection Against Retinal and Choroidal Neovascularization.
Topics: Acetates; Angiogenesis Inhibitors; Animals; Aorta; Cells, Cultured; Choroidal Neovascularization; Cyclopropanes; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C8 Inhibitors; Disease Models, Animal; Endothelial Cells; Fatty Acids, Omega-3; Genotype; Humans; Hyperoxia; Lasers; Mice, Inbred C57BL; Mice, Transgenic; Neovascularization, Physiologic; Phenotype; Quinolines; Retinal Neovascularization; Retinopathy of Prematurity; Sulfides; Tissue Culture Techniques | 2016 |
Effects of Montelukast in an Experimental Model of Acute Pancreatitis.
Topics: Acetates; Amylases; Animals; Ceruletide; Cyclopropanes; Disease Models, Animal; Edema; Leukotriene Antagonists; Lipase; Male; Pancreatitis; Quinolines; Rats; Rats, Sprague-Dawley; Sulfides | 2016 |
Montelukast, current indications and prospective future applications.
Topics: Acetates; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Asthma, Exercise-Induced; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2016 |
Lung Function Trajectory in Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Cell Transplant.
Topics: Acetates; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Azithromycin; Bronchiolitis Obliterans; Cyclopropanes; Drug Therapy, Combination; Female; Fluticasone; Forced Expiratory Volume; Hematopoietic Stem Cell Transplantation; Humans; Kaplan-Meier Estimate; Linear Models; Lung; Male; Middle Aged; Multivariate Analysis; Postoperative Complications; Prospective Studies; Quinolines; Retrospective Studies; Sulfides; Survival Rate; United States; Young Adult | 2016 |
Development of an enantioselective capillary electrophoretic method for the simultaneous determination of montelukast enantiomeric and diastereoisomeric forms and its main degradation product.
Topics: Acetates; Cyclopropanes; Electrophoresis, Capillary; Leukotriene Antagonists; Limit of Detection; Quinolines; Reference Standards; Reproducibility of Results; Stereoisomerism; Sulfides | 2016 |
The beneficial effects of Montelukast against 2,3,7,8-tetrachlorodibenzo- p -dioxin toxicity in female reproductive system in rats.
Topics: Acetates; Animals; Antioxidants; Catalase; Cyclopropanes; Female; Glutathione; Ovarian Follicle; Ovary; Oxidative Stress; Polychlorinated Dibenzodioxins; Quinolines; Random Allocation; Rats; Rats, Wistar; Sulfides; Superoxide Dismutase; Teratogens; Uterus | 2016 |
Eosinophilic gastroenteritis: a challenge to diagnose and treat.
Topics: Acetates; Adult; Anti-Bacterial Agents; Azathioprine; Biopsy; Budesonide; Clarithromycin; Cyclopropanes; Endoscopy; Enteritis; Eosinophilia; Eosinophils; Female; Gastritis; Gastroenteritis; Humans; Leukocyte Count; Macrolides; Mucous Membrane; Quinolines; Sulfides | 2016 |
Transporter-Mediated Hepatic Uptake Plays an Important Role in the Pharmacokinetics and Drug-Drug Interactions of Montelukast.
Topics: Acetates; Animals; Clarithromycin; Cyclopropanes; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Gemfibrozil; Haplorhini; Hepatocytes; Liver; Liver-Specific Organic Anion Transporter 1; Models, Biological; Nucleic Acid Synthesis Inhibitors; Organic Anion Transporters; Quinolines; Rats; Rifampin; Sulfides | 2017 |
Antenatal montelukast treatment reduces uterine activity associated with inflammation in a pregnant rat model.
Topics: Acetates; Animals; Cyclopropanes; Female; Inflammation; Leukotriene Antagonists; Myometrium; Pregnancy; Quinolines; Rats; Rats, Sprague-Dawley; Sulfides; Tocolytic Agents; Uterine Contraction; Uterus | 2016 |
Effect of montelukast on markers of airway remodeling in children with asthma.
Topics: Acetates; Adolescent; Airway Remodeling; Anti-Asthmatic Agents; Asthma; Biomarkers; Child; Cyclopropanes; Female; Humans; Male; Quinolines; Respiratory Function Tests; Sulfides; Treatment Outcome | 2016 |
Montelukast ameliorates streptozotocin-induced cognitive impairment and neurotoxicity in mice.
Topics: Acetates; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cognitive Dysfunction; Cyclopropanes; Disease Models, Animal; Hippocampus; Interleukin-1beta; Male; Maze Learning; Mice; Mice, Inbred ICR; Neurotoxicity Syndromes; Proto-Oncogene Proteins c-bcl-2; Quinolines; Receptors, Leukotriene; RNA, Messenger; Streptozocin; Sulfides; Tumor Necrosis Factor-alpha | 2016 |
Improvement of the chemical inhibition phenotyping assay by cross-reactivity correction.
Topics: Acetates; Cyclopropanes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Ketoconazole; Phenotype; Quinidine; Quinolines; Sulfaphenazole; Sulfides; Theophylline; Ticlopidine | 2016 |
Early patient experiences with montelukast orally disintegrating tablets in Japan: a cross-sectional survey of treatment satisfaction in patients with asthma and/or allergic rhinitis.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Asthma; Chemistry, Pharmaceutical; Cross-Sectional Studies; Cyclopropanes; Female; Humans; Japan; Leukotriene Antagonists; Male; Middle Aged; Patient Satisfaction; Quinolines; Rhinitis, Allergic; Sulfides; Surveys and Questionnaires; Tablets; Treatment Outcome; Young Adult | 2017 |
[Effect of montelukast sodium intervention on airway remodeling and percentage of Th17 cells/CD4+CD25+ regulatory T cells in asthmatic mice].
Topics: Acetates; Airway Remodeling; Animals; Asthma; Cyclopropanes; Female; Lung; Mice; Mice, Inbred BALB C; Quinolines; Sulfides; T-Lymphocytes, Regulatory; Th17 Cells | 2016 |
Pharmaceutical Rejuvenation of Age-Associated Decline in Spatial Memory.
Topics: Acetates; Aging; Animals; Blood-Brain Barrier; Cyclopropanes; Hippocampus; Leukotriene D4; Neurogenesis; Quinolines; Rats; Receptors, G-Protein-Coupled; Rejuvenation; Spatial Memory; Sulfides | 2016 |
GENETIC INTERACTIONS BETWEEN ADRB2 AND PTGER4 ON RESPONSES TO SALMETEROL OR MONTELUKAST IN JAPANESE PATIENTS WITH MILD PERSISTENT ASTHMA.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Female; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Quinolines; Receptors, Adrenergic, beta-2; Receptors, Prostaglandin E, EP4 Subtype; Salmeterol Xinafoate; Sulfides | 2016 |
The anti-inflammatory effect of montelukast, a cysteinyl leukotriene receptor-1 antagonist, against estradiol-induced nonbacterial inflammation in the rat prostate.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Chemokine CCL2; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; E-Selectin; Estradiol; Gene Expression Regulation; Inflammation Mediators; Interleukin-6; Leukotriene Antagonists; Leukotriene B4; Male; NF-kappa B; Nitric Oxide Synthase Type II; Orchiectomy; Prostate; Prostatitis; Quinolines; Rats, Wistar; Receptors, Leukotriene; Sulfides; Time Factors; Tumor Necrosis Factor-alpha | 2017 |
Aerosolizable modified-release particles of montelukast improve retention and availability of the drug in the lungs.
Topics: Acetates; Administration, Inhalation; Animals; Anti-Asthmatic Agents; Asthma; Biological Availability; Bronchoalveolar Lavage Fluid; Cyclopropanes; Drug Carriers; Humans; Lactic Acid; Lung; Macrophages, Alveolar; Male; Particle Size; Polyethyleneimine; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Quinolines; Rats; Rats, Sprague-Dawley; Sulfides | 2017 |
A Four-Year-Old Boy with Unusually Severe Obstructive Sleep Apnea.
Topics: Acetates; Child, Preschool; Cyclopropanes; Humans; Leukotriene Antagonists; Male; Polysomnography; Quinolines; Sleep Apnea, Obstructive; Sulfides | 2017 |
Clinical effect of treating secondary asthma attacks of children Mycoplasma pneumoniae with combined therapy of montelukast and azithromycin.
Topics: Acetates; Asthma; Azithromycin; Child; Cyclopropanes; Humans; Mycoplasma pneumoniae; Pneumonia, Mycoplasma; Quinolines; Sulfides | 2016 |
Low-Molecular-Weight Heparin-Coated and Montelukast-Filled Inhalable Particles: A Dual-Drug Delivery System for Combination Therapy in Asthma.
Topics: Acetates; Administration, Inhalation; Animals; Anti-Asthmatic Agents; Anticoagulants; Asthma; Cyclopropanes; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Therapy, Combination; Heparin, Low-Molecular-Weight; Inflammation Mediators; Male; Microspheres; Particle Size; Polyesters; Polyethylene Glycols; Quinolines; Rats; Rats, Sprague-Dawley; Sulfides | 2017 |
Interleukin-1α induced release of interleukin-8 by human bronchial epithelial cells in vitro: assessing mechanisms and possible treatment options.
Topics: Acetates; Acetylcysteine; Aminopyridines; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Azithromycin; Benzamides; Bronchi; Cell Line; Cyclopropanes; Dapsone; Dexamethasone; Dose-Response Relationship, Drug; Epithelial Cells; Fluoroquinolones; Humans; Interleukin-1alpha; Interleukin-8; MAP Kinase Signaling System; Moxifloxacin; Neutrophils; Phosphorylation; Pyridones; Quinolines; Sulfides; Theophylline; Treatment Outcome | 2017 |
The selective cysteinyl leukotriene receptor 1 (CysLT1R) antagonist montelukast regulates extracellular matrix remodeling.
Topics: Acetates; Cells, Cultured; Cyclopropanes; Dose-Response Relationship, Drug; Extracellular Matrix; Extracellular Matrix Proteins; Humans; Leukotriene Antagonists; Quinolines; Receptors, Leukotriene; Sulfides; Tenocytes; Wound Healing | 2017 |
Montelukast treatment protects nigral dopaminergic neurons against microglial activation in the 6-hydroxydopamine mouse model of Parkinson's disease.
Topics: Acetates; Adrenergic Agents; Animals; Calcium-Binding Proteins; Cyclopropanes; Cytokines; Disease Models, Animal; Dopaminergic Neurons; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Microfilament Proteins; Microglia; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Quinolines; Rotarod Performance Test; Substantia Nigra; Sulfides; Tyrosine 3-Monooxygenase | 2017 |
Gastroprotective effects of montelukast and Nigella sativa oil against corticosteroid-induced gastric damage: they are much more than antiasthmatic drugs.
Topics: Acetates; Adrenal Cortex Hormones; Animals; Anti-Asthmatic Agents; Cyclopropanes; Cytoprotection; Dexamethasone; Drug Interactions; Gastric Mucosa; Male; Nigella sativa; Oxidative Stress; Peroxidase; Plant Oils; Quinolines; Rats; Rats, Wistar; Stomach; Sulfides | 2017 |
Estimation of the Contribution of CYP2C8 and CYP3A4 in Repaglinide Metabolism by Human Liver Microsomes Under Various Buffer Conditions.
Topics: Acetates; Buffers; Carbamates; Cyclopropanes; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inducers; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Humans; Hypoglycemic Agents; Ketoconazole; Microsomes, Liver; Piperidines; Quinolines; Sulfides | 2017 |
Montelukast inhibits oxidized low-density lipoproteins (ox-LDL) induced vascular endothelial attachment: An implication for the treatment of atherosclerosis.
Topics: Acetates; Anti-Asthmatic Agents; Atherosclerosis; Blotting, Western; Cell Adhesion; Cell Line, Tumor; Cells, Cultured; Cyclopropanes; Dose-Response Relationship, Drug; E-Selectin; Endothelium, Vascular; Gene Expression; Human Umbilical Vein Endothelial Cells; Humans; Kruppel-Like Transcription Factors; Lipoproteins, LDL; Mitogen-Activated Protein Kinase 7; Molecular Structure; Monocytes; Protective Agents; Quinolines; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sulfides; Vascular Cell Adhesion Molecule-1 | 2017 |
Can the response to Omalizumab be influenced by treatment duration? A real-life study.
Topics: Acetates; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Female; Forced Expiratory Volume; Humans; Linear Models; Male; Middle Aged; Omalizumab; Quinolines; Retrospective Studies; Sulfides; Time Factors; Treatment Outcome | 2017 |
The Effect of Montelukast on Mild Persistent OSA after Adenotonsillectomy in Children: A Preliminary Study.
Topics: Acetates; Adenoidectomy; Administration, Oral; Age Factors; Child; Child, Preschool; Cohort Studies; Cyclopropanes; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Patient Satisfaction; Polysomnography; Quinolines; Risk Assessment; Severity of Illness Index; Sex Factors; Sleep Apnea, Obstructive; Sulfides; Tonsillectomy; Treatment Outcome | 2017 |
Asthma status is an independent risk factor for herpes zoster in children: a population-based cohort study.
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Asthma; Case-Control Studies; Child; Child, Preschool; Cyclopropanes; Drug Therapy, Combination; Emergency Service, Hospital; Female; Herpes Zoster; Humans; Infant; Male; Proportional Hazards Models; Quinolines; Retrospective Studies; Risk Factors; Sulfides; Taiwan | 2017 |
Urinary cysteinyl leukotriene E4 level and therapeutic response to montelukast in children with mild obstructive sleep apnea.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Biomarkers, Pharmacological; Child; Child, Preschool; Creatinine; Cyclopropanes; Disease Progression; Female; Humans; Leukotriene E4; Male; Predictive Value of Tests; Prognosis; Quinolines; Sleep Apnea, Obstructive; Sulfides | 2017 |
Fetal Exposure to Montelukast and Congenital Anomalies: A Population Based Study in Denmark.
Topics: Abnormalities, Drug-Induced; Acetates; Anti-Asthmatic Agents; Asthma; Congenital Abnormalities; Cross-Sectional Studies; Cyclopropanes; Denmark; Female; Humans; Odds Ratio; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnancy Trimester, First; Prenatal Exposure Delayed Effects; Quinolines; Registries; Sulfides | 2017 |
Biliverdin Reductase inhibitors did not improve severe unconjugated hyperbilirubinemia in vivo.
Topics: Acetates; Administration, Oral; Animals; Bilirubin; Cyclopropanes; Disulfiram; Drug Evaluation, Preclinical; Enzyme Inhibitors; HEK293 Cells; Humans; Hyperbilirubinemia; Liver; Male; Oxidoreductases Acting on CH-CH Group Donors; Quinolines; Rats; Sulfides | 2017 |
Cysteinyl Leukotriene Receptor Antagonists Inhibit Migration, Invasion, and Expression of MMP-2/9 in Human Glioblastoma.
Topics: Acetates; Brain Neoplasms; Cell Movement; Cell Survival; Cyclopropanes; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glioblastoma; Humans; Leukotriene Antagonists; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Quinolines; Receptors, Leukotriene; Sulfides | 2018 |
Montelukast improves the changes of cytoskeletal and adaptor proteins of human podocytes by interleukin-13.
Topics: Acetates; Actinin; Adaptor Proteins, Signal Transducing; B7-1 Antigen; beta Catenin; Cells, Cultured; Crk-Associated Substrate Protein; Cyclopropanes; Cytoskeletal Proteins; Humans; Interleukin-13; Leukotriene Antagonists; Microfilament Proteins; Podocytes; Quinolines; Sulfides; Zonula Occludens-1 Protein | 2017 |
Effect of the leukotriene receptor antagonist montelukast on orthodontic tooth movement.
Topics: Acetates; Animals; Cyclopropanes; Dogs; Leukotriene Antagonists; Male; Quinolines; Sulfides; Tooth Movement Techniques | 2017 |
Montelukast use-a 19-year nationwide drug utilisation study.
Topics: Acetates; Asthma; Cyclopropanes; Denmark; Drug Utilization Review; Humans; Pharmacoepidemiology; Quinolines; Sulfides | 2017 |
Adverse events are rare after single-dose montelukast exposures in children.
Topics: Acetates; Adolescent; Child; Child, Preschool; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Logistic Models; Male; Quinolines; Retrospective Studies; Sulfides | 2018 |
Leukotriene receptor antagonist attenuated airway inflammation and hyperresponsiveness in a double-stranded RNA-induced asthma exacerbation model.
Topics: Acetates; Alum Compounds; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Cyclopropanes; Cysteine; Cytokines; Disease Models, Animal; Disease Progression; Eosinophils; Immunization; Inflammation Mediators; Leukotriene Antagonists; Leukotrienes; Male; Mice; Ovalbumin; Poly I-C; Quinolines; Respiratory Hypersensitivity; RNA, Double-Stranded; RNA, Viral; Sulfides | 2017 |
Montelukast Induces Apoptosis-Inducing Factor-Mediated Cell Death of Lung Cancer Cells.
Topics: Acetates; Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Apoptosis; Apoptosis Inducing Factor; Biomarkers; Cell Death; Cell Line, Tumor; Cell Proliferation; Cyclopropanes; Disease Models, Animal; Humans; Leukotriene Antagonists; Lung Neoplasms; Models, Biological; Protein Transport; Quinolines; Signal Transduction; Sulfides; Tumor Burden; Xenograft Model Antitumor Assays | 2017 |
The effects of asthma medications on reactive oxygen species production in human monocytes.
Topics: Acetates; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Albuterol; Anti-Asthmatic Agents; Budesonide; Cyclopropanes; Fluticasone; Formoterol Fumarate; Humans; Indans; Leukotriene Antagonists; Monocytes; Quinolines; Quinolones; Reactive Oxygen Species; Salmeterol Xinafoate; Sulfides; THP-1 Cells | 2018 |
Montelukast reduces inhaled chlorine triggered airway hyperresponsiveness and airway inflammation in the mouse.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Bronchoalveolar Lavage Fluid; Cell Line; Chlorine; Cyclopropanes; Cytokines; Irritants; Leukotriene Antagonists; Lung; Male; Mice, Inbred BALB C; NF-E2-Related Factor 2; Quinolines; Receptors, Interleukin-6; Respiratory Hypersensitivity; Sulfides | 2017 |
Should we use montelukast in wheezy children?
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cyclopropanes; Humans; Practice Guidelines as Topic; Quinolines; Respiratory Sounds; Sulfides | 2017 |
Using the affective bias test to predict drug-induced negative affect: implications for drug safety.
Topics: Acetates; Affect; Animals; Carbamazepine; Choice Behavior; Corticosterone; Cyclopropanes; Drug Evaluation, Preclinical; Immunologic Factors; Interferon-alpha; Learning; Lipopolysaccharides; Male; Quinolines; Rats, Sprague-Dawley; Reward; Sucrose; Sulfides; Tetrabenazine; Varenicline | 2017 |
Neuropsychiatric adverse effects of montelukast in children.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Double-Blind Method; Humans; Quinolines; Sulfides | 2017 |
Neuropsychiatric adverse drug reactions in children initiated on montelukast in real-life practice.
Topics: Acetates; Adolescent; Aggression; Anti-Asthmatic Agents; Asthma; Canada; Child, Preschool; Cyclopropanes; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Glucocorticoids; Humans; Infant; Irritable Mood; Male; Neuropsychological Tests; Product Surveillance, Postmarketing; Quinolines; Retrospective Studies; Sleep Wake Disorders; Sulfides; Withholding Treatment | 2017 |
Renoprotective effects of montelukast in an experimental model of cisplatin nephrotoxicity in rats.
Topics: Acetates; Acute Kidney Injury; Animals; Caspase 3; Cisplatin; Cyclopropanes; Drug Evaluation, Preclinical; Kidney; Leukotriene Antagonists; Male; Quinolines; Rats, Sprague-Dawley; Sulfides | 2017 |
Comprehensive Pharmacogenomic Study Reveals an Important Role of UGT1A3 in Montelukast Pharmacokinetics.
Topics: Acetates; Adult; Area Under Curve; Cyclopropanes; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C8; Female; Glucuronosyltransferase; Humans; In Vitro Techniques; Liver-Specific Organic Anion Transporter 1; Male; Pharmacogenomic Testing; Polymorphism, Single Nucleotide; Quinolines; Sulfides; Sulfonylurea Receptors; Young Adult | 2018 |
Adverse drug reactions of montelukast in children and adults.
Topics: Acetates; Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Child; Child, Preschool; Churg-Strauss Syndrome; Cyclopropanes; Databases, Factual; Depression; Dreams; Female; Headache; Humans; Infant; Male; Middle Aged; Netherlands; Pharmacovigilance; Quinolines; Retrospective Studies; Sulfides; Young Adult | 2017 |
Back to the future of targeting leukotriene B
Topics: 5-Lipoxygenase-Activating Proteins; Acetates; Animals; Asthma; Cell Movement; Chemokines; Cyclopropanes; Epoxide Hydrolases; Humans; Inflammation; Leukotriene B4; Lipid Metabolism; Molecular Targeted Therapy; Neutrophil Activation; Neutrophils; Quinolines; Sulfides; T-Lymphocytes | 2017 |
Predictive Performance of Physiologically Based Pharmacokinetic (PBPK) Modeling of Drugs Extensively Metabolized by Major Cytochrome P450s in Children.
Topics: Acetates; Analgesics, Opioid; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Bronchodilator Agents; Child; Child, Preschool; Cyclopropanes; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diclofenac; Esomeprazole; Histamine H1 Antagonists, Non-Sedating; Humans; Infant; Infant, Newborn; Itraconazole; Lansoprazole; Loratadine; Models, Biological; Ondansetron; Pharmaceutical Preparations; Pharmacokinetics; Proton Pump Inhibitors; Quinolines; Serotonin Antagonists; Sufentanil; Sulfides; Theophylline; Tramadol | 2018 |
The role of cysteinyl leukotrienes and their receptors in refractory nasal polyps.
Topics: Acetates; Adult; Cyclopropanes; Cysteine; Cytokines; Enterotoxins; Female; Gene Expression Regulation; Humans; Leukotriene Antagonists; Leukotrienes; Male; Middle Aged; Nasal Polyps; Quinolines; Receptors, Leukotriene; Sinusitis; Sulfides | 2017 |
Antagonism of cysteinyl leukot-riene receptor 1 (cysLT1R) by montelukast regulates differentiation of MC3T3-E1 cells under overloaded mechanical environment.
Topics: 3T3 Cells; Acetates; Animals; Cell Differentiation; Cyclopropanes; Gene Expression Regulation, Developmental; Leukotriene Antagonists; Mechanotransduction, Cellular; Mice; Osteoblasts; Osteogenesis; Quinolines; Receptors, Leukotriene; Stress, Mechanical; Sulfides | 2018 |
In Reference to "The Effect of Montelukast on Mild Persistent OSA after Adenotonsillectomy in Children: A Preliminary Study".
Topics: Acetates; Adenoidectomy; Child; Cyclopropanes; Humans; Quinolines; Sleep Apnea, Obstructive; Sulfides; Tonsillectomy; Treatment Outcome | 2017 |
Response to "In Reference to 'The Effect of Montelukast on Mild Persistent OSA after Adenotonsillectomy in Children: A Preliminary Study'".
Topics: Acetates; Adenoidectomy; Child; Cyclopropanes; Humans; Quinolines; Sleep Apnea, Obstructive; Sulfides; Tonsillectomy; Treatment Outcome | 2017 |
Leukotriene receptor antagonism may not be effective in atopic dermatitis treatment after all.
Topics: Acetates; Cyclopropanes; Dermatitis, Atopic; Humans; Leukotriene Antagonists; Quinolines; Randomized Controlled Trials as Topic; Sulfides; Treatment Outcome | 2018 |
Hydroxychloroquine as a steroid-sparing agent in an infant with chronic urticaria.
Topics: Acetates; Anti-Inflammatory Agents; Antimalarials; Cetirizine; Chronic Disease; Cyclopropanes; Diphenhydramine; Drug Resistance; Histamine Antagonists; Humans; Hydroxychloroquine; Infant; Male; Quinolines; Ranitidine; Skin; Sulfides; Urticaria | 2018 |
Neuropsychiatric adverse drug reactions in children initiated on montelukast in real-life practice.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Humans; Quinolines; Sulfides | 2017 |
Neuropsychiatric adverse drug reactions in children initiated on montelukast in real-life practice.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Humans; Quinolines; Sulfides | 2017 |
Role of montelukast in management of episodic viral wheeze.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Australia; Cyclopropanes; Humans; Quinolines; Respiratory Sounds; Sulfides | 2017 |
A Prospective Study on the Prevalence, Extent of Disease and Outcome of Eosinophilic Gastroenteritis in Patients Presenting with Lower Abdominal Symptoms.
Topics: Abdominal Pain; Acetates; Adolescent; Adult; Anti-Inflammatory Agents; Colon, Descending; Colon, Sigmoid; Colonoscopy; Cyclopropanes; Drug Therapy, Combination; Enteritis; Eosinophilia; Female; Gastric Mucosa; Gastritis; Humans; Ketotifen; Male; Middle Aged; Prednisolone; Prevalence; Prospective Studies; Quinolines; Republic of Korea; Sulfides; Treatment Outcome; Young Adult | 2018 |
The cysteinyl leukotriene receptor 1 (CysLT1R) antagonist montelukast suppresses matrix metalloproteinase-13 expression induced by lipopolysaccharide.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Bone Diseases; Cell Line; Cyclopropanes; Gene Expression Regulation; Humans; Lipopolysaccharides; Matrix Metalloproteinase 13; Mice; NF-kappa B; Osteoblasts; Quinolines; Receptors, Leukotriene; RNA, Small Interfering; Sulfides; Suppressor of Cytokine Signaling 3 Protein | 2018 |
Acute Lung Toxicity After Intralesional Bleomycin Sclerotherapy.
Topics: Acetates; Acute Lung Injury; Bleomycin; Child, Preschool; Cyclopropanes; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Injections, Intralesional; Methylprednisolone; Quinolines; Risk Assessment; Sclerotherapy; Sulfides; Tomography, X-Ray Computed; Treatment Outcome; Vascular Malformations | 2018 |
Rothia mucilaginosa bacteraemia in an immunocompetent paediatric patient: a new pathogen to take into account. A case report.
Topics: Acetates; Actinomycetales Infections; Anti-Asthmatic Agents; Asthma; Bacteremia; Communicable Diseases, Emerging; Cyclopropanes; Herpangina; Humans; Immunocompetence; Infant; Male; Micrococcaceae; Otitis Media; Quinolines; Sulfides | 2017 |
Introduction: Biocatalysis in Industry.
Topics: Acetates; Biocatalysis; Biotechnology; Cyclopropanes; Enzymes; Esomeprazole; Industry; Protein Engineering; Quinolines; Sulfides | 2018 |
Antagonism of cysteinyl leukotriene receptor 1 (cysLTR1) by montelukast suppresses cell senescence of chondrocytes.
Topics: Acetates; Adult; Cellular Senescence; Chondrocytes; Cyclin-Dependent Kinase Inhibitor p21; Cyclopropanes; Female; Humans; Male; Plasminogen Activator Inhibitor 1; Quinolines; Receptors, Leukotriene; Sulfides; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Up-Regulation | 2018 |
Cysteinyl leukotriene receptor 1 regulates glucose-stimulated insulin secretion (GSIS).
Topics: Acetates; ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Animals; cdc42 GTP-Binding Protein; Cell Line, Tumor; Cyclopropanes; Cysteine; Diabetes Mellitus, Type 2; Glucose; Insulin Secretion; Insulin-Secreting Cells; Leukotrienes; Mice; Neuropeptides; Quinolines; rac1 GTP-Binding Protein; Receptors, Leukotriene; Sulfides | 2018 |
Cysteinyl leukotriene receptor 1 antagonism prevents experimental abdominal aortic aneurysm.
Topics: Acetates; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Chemokine CCL3; Cyclopropanes; Disease Models, Animal; Leukotriene Antagonists; Matrix Metalloproteinase 9; Mice; Mice, Knockout, ApoE; Quinolines; Receptors, Leukotriene; Sulfides | 2018 |
Early Discontinuation of Montelukast Treatment; A Danish Nationwide Utilization Study.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Aged; Asthma; Child; Child, Preschool; Cyclopropanes; Denmark; Drug Prescriptions; Drug Utilization; Female; Glucocorticoids; Humans; Infant; Infant, Newborn; Leukotriene Antagonists; Male; Middle Aged; Off-Label Use; Patents as Topic; Patient Compliance; Quinolines; Registries; Risk Factors; Sulfides; Time Factors; Young Adult | 2018 |
γ-Irradiated chitosan based injectable hydrogels for controlled release of drug (Montelukast sodium).
Topics: Acetates; Chitosan; Cross-Linking Reagents; Cyclopropanes; Delayed-Action Preparations; Drug Delivery Systems; Drug Evaluation, Preclinical; Drug Liberation; Escherichia coli; Gamma Rays; Glycerol; Hydrogels; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Microscopy, Electron, Scanning; Molecular Weight; Polyvinyl Alcohol; Porosity; Quinolines; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Sulfides | 2018 |
Montelukast reverses airway remodeling in actively sensitized young mice.
Topics: Acetates; Age Factors; Airway Remodeling; Allergens; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Cyclopropanes; Disease Models, Animal; Female; Lung; Mice, Inbred BALB C; Ovalbumin; Quinolines; Sulfides | 2018 |
[Severe Mast Cell Activation Syndrome in a 15-year-old patient with an hypermobile Ehlers-Danlos syndrome].
Topics: Acetates; Adolescent; Antioxidants; Ascorbic Acid; Cetirizine; Cyclopropanes; Ehlers-Danlos Syndrome; Histamine H1 Antagonists, Non-Sedating; Histamine H2 Antagonists; Humans; Male; Mastocytosis; Quinolines; Ranitidine; Sulfides | 2018 |
Leukotriene Receptor Antagonists Inhibit Mitogenic Activity in Triple Negative Breast Cancer Cells
Topics: Acetates; Apoptosis; Cell Cycle; Cell Proliferation; Cyclopropanes; Female; Humans; Indoles; Leukotriene Antagonists; Mitogens; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds; Triple Negative Breast Neoplasms; Tumor Cells, Cultured | 2018 |
Leukotriene D4 induces cellular senescence in osteoblasts.
Topics: Acetates; Animals; beta-Galactosidase; Cell Line; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Cyclopropanes; Humans; Leukotriene D4; Mice; Osteoblasts; Osteoporosis; Plasminogen Activator Inhibitor 1; Quinolines; Receptors, Leukotriene; RNA, Small Interfering; Sirtuin 1; Sulfides; Tumor Suppressor Protein p53 | 2018 |
The Variants in the 3' Untranslated Region of the Matrix Metalloproteinase 9 Gene as Modulators of Treatment Outcome in Children with Asthma.
Topics: 3' Untranslated Regions; Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Child; Cyclopropanes; Female; Fluticasone; Forced Expiratory Volume; Genetic Variation; Humans; Male; Matrix Metalloproteinase 9; Nitric Oxide; Prognosis; Quinolines; Respiration; Respiratory Hypersensitivity; Sequence Analysis, DNA; Slovenia; Sulfides; Treatment Outcome; Vital Capacity | 2018 |
Montelukast attenuates radioactive I131-induced pulmonary damage on rats.
Topics: Acetates; Animals; Cyclopropanes; Female; Iodine Radioisotopes; Lung; Quinolines; Radiation-Protective Agents; Rats; Rats, Wistar; Sulfides | 2018 |
[The patients' cost of the montelukast therapy due to the generic substitution].
Topics: Acetates; Anti-Asthmatic Agents; Cyclopropanes; Drug Costs; Drug Prescriptions; Drug Substitution; Drugs, Generic; Economic Competition; Humans; Hungary; Insurance Coverage; Insurance, Pharmaceutical Services; National Health Programs; Quinolines; Sulfides | 2018 |
Mepolizumab in the treatment of severe eosinophilic asthma: Results from a physician in the field.
Topics: Acetates; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Anti-Asthmatic Agents; Antibodies, Monoclonal, Humanized; Asthma; Cyclopropanes; Drug Administration Schedule; Eosinophils; Female; Humans; Injections, Subcutaneous; Interleukin-5; Male; Middle Aged; Prednisone; Pulmonary Eosinophilia; Quinolines; Retrospective Studies; Rhinitis, Allergic; Severity of Illness Index; Sulfides; Surveys and Questionnaires | 2018 |
Montelukast inhibits hypoxia inducible factor-1α translation in prostate cancer cells.
Topics: Acetates; Cell Line, Tumor; Cell Proliferation; Cyclopropanes; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Prostatic Neoplasms; Protein Biosynthesis; Proteolysis; Quinolines; Receptors, Leukotriene; Sulfides | 2018 |
Cysteinyl leukotriene receptor antagonists induce apoptosis and inhibit proliferation of human glioblastoma cells by downregulating B-cell lymphoma 2 and inducing cell cycle arrest.
Topics: Acetates; Apoptosis; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cyclopropanes; Down-Regulation; G1 Phase; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Indoles; Leukotriene Antagonists; Phenylcarbamates; Proto-Oncogene Proteins c-bcl-2; Quinolines; Resting Phase, Cell Cycle; Sulfides; Sulfonamides; Tosyl Compounds; Up-Regulation | 2018 |
The protective effect of Montelukast against skeletal muscle ischemia reperfusion injury: An experimental rat model.
Topics: Acetates; Animals; Cyclopropanes; Male; Malondialdehyde; Muscle, Skeletal; Protective Agents; Quinolines; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Sulfides | 2018 |
Montelukast, a cysteinyl leukotriene receptor antagonist, inhibits the growth of chronic myeloid leukemia cells through apoptosis.
Topics: Acetates; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cyclopropanes; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukotriene Antagonists; Protein Kinase Inhibitors; Quinolines; Receptors, Leukotriene; Signal Transduction; Sulfides | 2018 |
Amenamevir: Studies of Potential CYP2C8- and CYP2B6-Mediated Pharmacokinetic Interactions With Montelukast and Bupropion in Healthy Volunteers.
Topics: Acetates; Adolescent; Adult; Bupropion; Cyclopropanes; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2B6 Inducers; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C8 Inhibitors; Drug Interactions; Healthy Volunteers; Hepatocytes; Humans; Male; Middle Aged; Oxadiazoles; Quinolines; Sulfides; Young Adult | 2018 |
[Infusion of Daratumumab in Combination Therapies - Practical Information for The Outpatient Area].
Topics: Acetates; Ambulatory Care; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Cyclopropanes; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Histamine H2 Antagonists; Humans; Infusions, Intravenous; Methylprednisolone; Multiple Myeloma; Premedication; Quinolines; Randomized Controlled Trials as Topic; Sulfides; Time Factors | 2018 |
Effect of montelukast in experimental model of Parkinson's disease.
Topics: Acetates; Animals; Cyclopropanes; Inflammation Mediators; Leukotriene Antagonists; Male; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Quinolines; Rats; Rats, Wistar; Rotenone; Sulfides; Treatment Outcome | 2018 |
Montelukast inhibits inflammatory response in rheumatoid arthritis fibroblast-like synoviocytes.
Topics: Acetates; Arthritis, Rheumatoid; Cells, Cultured; Cellular Microenvironment; Cyclopropanes; Cytokines; Fibroblasts; Humans; I-kappa B Kinase; Inflammation Mediators; Matrix Metalloproteinase 13; Matrix Metalloproteinase 3; NF-kappa B; Phosphorylation; Quinolines; Receptors, Leukotriene; Signal Transduction; Sulfides; Synoviocytes; Synovitis | 2018 |
Effects of anti-allergic drugs on T cell-mediated nasal hyperresponsiveness in a murine model of allergic rhinitis.
Topics: Acetates; Animals; Anti-Allergic Agents; CD4-Positive T-Lymphocytes; Chlorpheniramine; Cyclopropanes; Cytokines; Dexamethasone; Disease Models, Animal; Female; Immunoglobulin E; Immunoglobulin G; Mice; Mice, Inbred BALB C; Nasal Lavage Fluid; Nasal Mucosa; Quinolines; Rhinitis, Allergic; Sulfides | 2018 |
Montelukast inhibits RANKL‑induced osteoclast formation and bone loss via CysLTR1 and P2Y12.
Topics: Acetates; Animals; Bone Marrow Cells; Bone Resorption; Cell Differentiation; Cyclopropanes; Humans; Macrophages; Mice; Osteoclasts; Ovariectomy; Quinolines; RANK Ligand; Receptors, Leukotriene; Receptors, Purinergic P2Y12; Signal Transduction; Sulfides | 2018 |
Cysteinyl-leukotriene pathway as a new therapeutic target for the treatment of atherosclerosis related to obstructive sleep apnea syndrome.
Topics: 5-Lipoxygenase-Activating Proteins; Acetates; Adult; Animals; Arachidonate 5-Lipoxygenase; Atherosclerosis; Case-Control Studies; Cyclopropanes; Cysteine; Disease Models, Animal; Disease Progression; Female; Humans; Leukotriene Antagonists; Leukotriene E4; Leukotrienes; Male; Mice, Knockout, ApoE; Middle Aged; Plaque, Atherosclerotic; Quinolines; Receptors, Leukotriene; Risk Factors; Signal Transduction; Sleep Apnea, Obstructive; Sulfides | 2018 |
The anti-asthmatic drug, montelukast, modifies the neurogenic potential in the young healthy and irradiated brain.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Brain; Cyclopropanes; Enzyme-Linked Immunosorbent Assay; Female; Fluorometry; Hippocampus; Immunohistochemistry; Mice; Neurogenesis; Quinolines; Sulfides | 2018 |
Autism and Allergy - Are They Linked?
Topics: Acetates; Anti-Asthmatic Agents; Antipsychotic Agents; Asthma; Autism Spectrum Disorder; Bronchodilator Agents; Child; Cyclopropanes; Drug Therapy, Combination; Female; Fluticasone-Salmeterol Drug Combination; Humans; Quinolines; Rhinitis, Allergic; Risperidone; Sulfides; Treatment Outcome | 2018 |
Protective effect of melatonin versus montelukast in cisplatin-induced seminiferous tubule damage in rats.
Topics: Acetates; Animals; Antineoplastic Agents; Antioxidants; Body Weight; Cisplatin; Cyclopropanes; Drug Evaluation, Preclinical; Leukotriene Antagonists; Male; Melatonin; Organ Size; Oxidative Stress; Quinolines; Rats, Wistar; Semen Analysis; Seminiferous Tubules; Sulfides; Testicular Diseases | 2018 |
Montelukast and budesonide combination for children with chronic cough-variant asthma.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Budesonide; Child; Child, Preschool; Cough; Cyclopropanes; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Male; Quinolines; Respiratory Function Tests; Retrospective Studies; Sulfides; Symptom Assessment; Treatment Outcome | 2018 |
Mechanisms underlying the protective effect of montelukast in prevention of endometrial hyperplasia in female rats.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Antioxidants; Cholesterol; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Endometrial Hyperplasia; Estradiol; Female; Nitric Oxide Synthase Type II; Oxidative Stress; Quinolines; Rats; Rats, Wistar; Sulfides; Tumor Necrosis Factor-alpha | 2018 |
Innovative HPTLC method with fluorescence detection for assessment of febuxostat-montelukast combination and study of their protective effects against gouty arthritis.
Topics: Acetates; Animals; Arthritis, Gouty; Calibration; Chromatography, Thin Layer; Cyclopropanes; Febuxostat; Fluorescence; Humans; Male; Quinolines; Rats; Rats, Wistar; Reproducibility of Results; Sulfides | 2018 |
In Vitro Drug-Drug Interaction Potential of Sulfoxide and/or Sulfone Metabolites of Albendazole, Triclabendazole , Aldicarb, Methiocarb, Montelukast and Ziprasidone.
Topics: Acetates; Albendazole; Aldicarb; Biotransformation; Cyclopropanes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Humans; Isoenzymes; Methiocarb; Microsomes, Liver; Piperazines; Quinolines; Risk Assessment; Sulfides; Sulfones; Sulfoxides; Thiazoles; Triclabendazole | 2018 |
Montelukast nasal spray: formulation development and in vitro evaluation.
Topics: Acetates; Anti-Asthmatic Agents; Cell Line; Cell Survival; Cyclopropanes; Dose-Response Relationship, Drug; Drug Compounding; Drug Development; Drug Evaluation, Preclinical; Epithelial Cells; Humans; Nasal Sprays; Quinolines; Sulfides | 2019 |
Treatment with montelukast and antidepressive medication-a symmetry analysis.
Topics: Acetates; Adult; Aged; Antidepressive Agents; Asthma; Cyclopropanes; Denmark; Depression; Drug Prescriptions; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Rhinitis, Allergic; Severity of Illness Index; Sulfides; Young Adult | 2018 |
Ancillary medications and outcomes in post-tonsillectomy patients.
Topics: Acetates; Adenoidectomy; Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Child, Preschool; Cyclopropanes; Dehydration; Female; Humans; Infant; Male; Outcome Assessment, Health Care; Pain, Postoperative; Postoperative Hemorrhage; Quinolines; Risk Factors; Sulfides; Tonsillectomy | 2018 |
Montelukast, a CysLT1 receptor antagonist, reduces colon cancer stemness and tumor burden in a mouse xenograft model of human colon cancer.
Topics: Acetates; Animals; Cell Line, Tumor; Colonic Neoplasms; Cyclopropanes; Female; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Leukotriene Antagonists; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Quinolines; Receptors, Leukotriene; Sulfides; Tumor Burden; Xenograft Model Antitumor Assays | 2018 |
[Effects of cysteinyl leukotriene receptors on phagocytosis of mouse microglial cells].
Topics: Acetates; Animals; Cell Line; Cyclohexanecarboxylic Acids; Cyclopropanes; Lipopolysaccharides; Mice; Microglia; Phagocytosis; Phthalic Acids; Protein Binding; Quinolines; Receptors, Leukotriene; Sulfides | 2018 |
Montelukast attenuates rotenone-induced microglial activation/p38 MAPK expression in rats: Possible role of its antioxidant, anti-inflammatory and antiapoptotic effects.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cyclopropanes; Gene Expression Regulation, Enzymologic; Insecticides; Leukotriene Antagonists; Male; Microglia; p38 Mitogen-Activated Protein Kinases; Quinolines; Rats; Rats, Wistar; Rotenone; Sulfides | 2018 |
Improving Confidence in the Determination of Free Fraction for Highly Bound Drugs Using Bidirectional Equilibrium Dialysis.
Topics: Acetates; Blood Proteins; Bridged Bicyclo Compounds, Heterocyclic; Buffers; Chromatography, High Pressure Liquid; Cyclopropanes; Dialysis; Diarylquinolines; Drug Monitoring; Feasibility Studies; Half-Life; Humans; Proof of Concept Study; Protein Binding; Quinolines; Reproducibility of Results; Sulfides; Sulfonamides; Tandem Mass Spectrometry; Tissue Distribution | 2019 |
Plasma tryptase elevation during aspirin-induced reactions in aspirin-exacerbated respiratory disease.
Topics: Acetates; Administration, Oral; Adult; Airway Obstruction; Allergens; Anti-Asthmatic Agents; Aspirin; Asthma, Aspirin-Induced; Cyclopropanes; Drug Hypersensitivity; Female; Humans; Immunization; Male; Mast Cells; Middle Aged; Plasma; Quinolines; Respiratory System; Sulfides; Tryptases | 2019 |
Montelukast enhances cytocidal effects of carfilzomib in multiple myeloma by inhibiting mTOR pathway.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Cell Line, Tumor; Cyclopropanes; Disease Models, Animal; Humans; Mice; Multiple Myeloma; Oligopeptides; Quinolines; Sulfides; TOR Serine-Threonine Kinases; Transfection; Xenograft Model Antitumor Assays | 2019 |
Is there any effect of montelukast on prevention of myringosclerosis after myringotomy in a rat model?
Topics: Acetates; Animals; Cyclopropanes; Cytochrome P-450 CYP1A2 Inducers; Disease Models, Animal; Female; Middle Ear Ventilation; Myringosclerosis; Quinolines; Rats; Rats, Wistar; Sulfides; Tympanic Membrane | 2019 |
Antileukotrienes improve naso-ocular symptoms and biomarkers in patients with NARES and asthma.
Topics: Acetates; Adult; Asthma; Biomarkers; Cyclopropanes; Eosinophilia; Eye Diseases; Female; Humans; Leukotriene Antagonists; Male; Nose Diseases; Prospective Studies; Quinolines; Rhinitis; Sulfides; Syndrome | 2019 |
Exosomes and cells from lung cancer pleural exudates transform LTC4 to LTD4, promoting cell migration and survival via CysLT1.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Apoptosis; Biomarkers, Tumor; Cell Movement; Cell Proliferation; Cyclopropanes; Exosomes; Female; Follow-Up Studies; Humans; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Lung Neoplasms; Male; Middle Aged; Pleural Neoplasms; Prognosis; Quinolines; Receptors, Leukotriene; Sulfides; Survival Rate; Tumor Cells, Cultured | 2019 |
Montelukast Sodium Formulation Containing Green Tea Extract to Reduce the Oxidative Stress in Guinea Pig Model of Chronic Allergic Asthma.
Topics: Acetates; Administration, Oral; Animals; Anti-Asthmatic Agents; Asthma; Chronic Disease; Cyclopropanes; Drug Combinations; Female; Glutathione; Guinea Pigs; Histamine; Liver; Lung; Male; Malondialdehyde; Oxidative Stress; Oxygen Radical Absorbance Capacity; Patents as Topic; Plant Extracts; Quinolines; Sulfides; Tea | 2018 |
Preformulation Studies of the γ-Cyclodextrin and Montelukast Inclusion Compound Prepared by Comilling.
Topics: Acetates; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Cyclopropanes; Drug Compounding; Freeze Drying; gamma-Cyclodextrins; Microscopy, Electron, Scanning; Models, Molecular; Powders; Quinolines; Solubility; Spectroscopy, Fourier Transform Infrared; Sulfides; X-Ray Diffraction | 2019 |
[Effects of montelukast sodium and bacterial lysates on airway remodeling and expression of transforming growth factor-β1 and Smad7 in guinea pigs with bronchial asthma].
Topics: Acetates; Airway Remodeling; Animals; Asthma; Cell Extracts; Cyclopropanes; Guinea Pigs; Lung; Male; Ovalbumin; Quinolines; Sulfides; Transforming Growth Factor beta1 | 2018 |
Effects of montelukast on human nasal mucosa.
Topics: Acetates; Anti-Asthmatic Agents; Cyclopropanes; Electric Stimulation; Humans; In Vitro Techniques; Leukotriene Antagonists; Methoxamine; Muscle, Smooth; Nasal Mucosa; Nasal Sprays; Quinolines; Sulfides; Vasoconstriction; Vasoconstrictor Agents | 2019 |
Influence of leukotriene receptor antagonist on contractile activity of the porcine uterine smooth muscle in the luteal phase and in early pregnancy.
Topics: Acetates; Animals; Cyclopropanes; Female; Leukotriene Antagonists; Luteal Phase; Pregnancy; Pregnancy, Animal; Quinolines; Sulfides; Swine; Uterine Contraction | 2018 |
Montelukast in chronic lung allograft dysfunction after lung transplantation.
Topics: Acetates; Adult; Allografts; Chronic Disease; Cyclopropanes; Cytochrome P-450 CYP1A2 Inducers; Female; Follow-Up Studies; Forced Expiratory Volume; Graft Rejection; Humans; Lung Transplantation; Male; Middle Aged; Postoperative Period; Quinolines; Retrospective Studies; Sulfides; Transplant Recipients | 2019 |
Characterization of cysteinyl leukotriene-related receptors and their interactions in a mouse model of asthma.
Topics: Acetates; Animals; Asthma; Clopidogrel; Cyclohexanecarboxylic Acids; Cyclopropanes; Disease Models, Animal; Drug Therapy, Combination; Eosinophils; Female; Inflammation; Interleukins; Leukotriene Antagonists; Mice; Mice, Inbred BALB C; Ovalbumin; Phthalic Acids; Purinergic P2Y Receptor Antagonists; Quinolines; Receptors, Leukotriene; Receptors, Purinergic P2Y12; Sulfides; Th2 Cells | 2019 |
Montelukast for chronic lung allograft dysfunction: Not quite the "Full Monty".
Topics: Acetates; Allografts; Cyclopropanes; Lung; Lung Transplantation; Quinolines; Sulfides | 2019 |
[Association of cytoplasmic phospholipase A2 gene polymorphism with bronchial asthma and response to montelukast in children].
Topics: Acetates; Asthma; Child; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2019 |
Improvement of fiber connectivity and functional recovery after stroke by montelukast, an available and safe anti-asthmatic drug.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Brain; Cyclopropanes; Infarction, Middle Cerebral Artery; Macrophages; Male; Mice; Microglia; Neuroprotective Agents; Quinolines; Stroke; Sulfides | 2019 |
Nasal Symptoms Reduction and Decreased Neutrophilia in Japanese Cedar Pollinosis With Prophylactic Treatment With a Combination of Montelukast, Fexofenadine, and Fluticasone Nasal Spray.
Topics: Acetates; Adult; Anti-Allergic Agents; Cetirizine; Cryptomeria; Cyclopropanes; Drug Therapy, Combination; Female; Fluticasone; Humans; Leukocyte Count; Leukotriene Antagonists; Male; Mast Cells; Middle Aged; Nasal Cavity; Nasal Sprays; Neutrophils; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides; Terfenadine; Treatment Outcome | 2019 |
Real-life experience in the treatment of solar urticaria: retrospective cohort study.
Topics: Acetates; Adolescent; Adult; Aged; Anti-Allergic Agents; Cetirizine; Child; Cohort Studies; Cyclopropanes; Disease Management; Female; Histamine Antagonists; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Omalizumab; Photosensitivity Disorders; Quinolines; Retrospective Studies; Sulfides; Terfenadine; Urticaria; Young Adult | 2019 |
Effect of Montelukast on Bronchopulmonary Dysplasia (BPD) and Related Mechanisms.
Topics: Acetates; Animals; Animals, Newborn; Apoptosis; Bronchopulmonary Dysplasia; Cyclopropanes; Disease Models, Animal; Hyperoxia; Interleukin-1beta; Interleukin-6; Lung; Lung Injury; Mice; Mice, Inbred C57BL; Oxidative Stress; Quinolines; Receptors, Leukotriene; Sulfides; Tumor Necrosis Factor-alpha | 2019 |
Challenges and safety of beta-lactam desensitization during extracorporeal membrane oxygenation.
Topics: Acetates; Allergens; Anaphylaxis; Anti-Infective Agents; Antibiotic Prophylaxis; beta-Lactams; Cetirizine; Cyclopropanes; Cystic Fibrosis; Desensitization, Immunologic; Drug Hypersensitivity; Extracorporeal Membrane Oxygenation; Famotidine; Female; Humans; Immune Tolerance; Male; Quinolines; Respiratory Insufficiency; Sulfides | 2019 |
Montelukast and Neuropsychiatric Events in Children with Asthma: A Nested Case-Control Study.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Case-Control Studies; Child; Child, Preschool; Cyclopropanes; Female; Humans; Male; Mental Disorders; Nervous System Diseases; Quinolines; Sulfides | 2019 |
Montelukast and Budesonide for Childhood Cough Variant Asthma.
Topics: Acetates; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Budesonide; C-Reactive Protein; Child; Child, Preschool; Cough; Cyclopropanes; Female; Humans; Interleukin-6; Lung; Male; Quinolines; Respiratory Function Tests; Sulfides; Treatment Outcome; Tumor Necrosis Factor-alpha | 2019 |
Colonic anastomosis can be protected from ischemia reperfusion injury with intra-peritoneal Montelukast treatment.
Topics: Acetates; Anastomosis, Surgical; Animals; Colon; Cyclopropanes; Male; Quinolines; Rats, Wistar; Reperfusion Injury; Sulfides | 2020 |
Eosinophilic Granulomatosis with Polyangiitis in a 4-Year-Old Child: Is Montelukast and/or Clarithromycin a Trigger?
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Child, Preschool; Cyclopropanes; Eosinophils; Female; Granulomatosis with Polyangiitis; Humans; Quinolines; Sulfides | 2019 |
Adverse events associated with weight-based, high-dose montelukast exposures in children.
Topics: Acetates; Asthma; Body Weight; Child; Cyclopropanes; Dose-Response Relationship, Drug; Drug Dosage Calculations; Female; Humans; Leukotriene Antagonists; Male; Poison Control Centers; Quinolines; Sulfides | 2020 |
Effect of Montelukast, a Cysteinyl Leukotriene Receptor-1 Antagonist, on a Rat Model of Acute Bacterial Sinonasal Inflammation.
Topics: Acetates; Animals; Anti-Bacterial Agents; Cefazolin; Cyclopropanes; Cytokines; Disease Models, Animal; Inflammation; Leukotriene Antagonists; Male; Nasal Septum; Quinolines; Rats; Rats, Wistar; Rhinitis; Sinusitis; Staphylococcal Infections; Staphylococcus aureus; Sulfides; Treatment Outcome; Turbinates | 2019 |
Retrospective study of budesonide in children with eosinophilic gastroenteritis.
Topics: Acetates; Adolescent; Biopsy; Budesonide; Child; Child, Preschool; Cyclopropanes; Endoscopy; Enteritis; Eosinophilia; Eosinophils; Female; Gastritis; Humans; Infant; Male; Prednisone; Quinolines; Retrospective Studies; Sulfides; Treatment Outcome | 2019 |
Neuropsychiatric side effects of montelukast.
Topics: Acetates; Asthma; Case-Control Studies; Child; Cyclopropanes; Humans; Quinolines; Sulfides | 2019 |
Reply.
Topics: Acetates; Asthma; Case-Control Studies; Child; Cyclopropanes; Humans; Quinolines; Sulfides | 2019 |
Montelukast, Leukotriene Inhibitor, Reduces LPS-Induced Acute Lung Inflammation and Human Neutrophil Activation.
Topics: Acetates; Animals; Bronchoalveolar Lavage; Capillary Permeability; Cyclopropanes; Cytokines; Humans; Leukocyte Count; Leukotriene Antagonists; Lipopolysaccharides; Lung; Lymphocytes; Macrophages; Mice; Mice, Inbred C57BL; Neutrophil Activation; Neutrophils; NF-kappa B; Pneumonia; Quinolines; Receptors, Leukotriene B4; Respiratory Distress Syndrome; Sulfides; Time Factors; Vascular Endothelial Growth Factor A | 2019 |
Impact of montelukast and fluticasone on quality of life in mild pediatric sleep apnea.
Topics: Acetates; Adenoidectomy; Adolescent; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Child; Child, Preschool; Cyclopropanes; Female; Fluticasone; Humans; Male; Pediatric Obesity; Prospective Studies; Quality of Life; Quinolines; Sleep Apnea Syndromes; Sulfides; Tonsillectomy | 2019 |
Montelukast, a Cysteinyl Leukotriene Receptor 1 Antagonist, Induces M2 Macrophage Polarization and Inhibits Murine Aortic Aneurysm Formation.
Topics: Acetates; Animals; Aorta; Aortic Aneurysm; Arginase; Cell Line; Cell Polarity; Chemokines; Cyclopropanes; Gene Expression Regulation; Inflammation Mediators; Intercellular Signaling Peptides and Proteins; Interleukin-10; Macrophages; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Quinolines; Receptors, Leukotriene; Sulfides; Tumor Necrosis Factor-alpha | 2019 |
Cysteinyl leukotriene receptor antagonism: a promising pharmacological strategy for lowering the severity of arthritis.
Topics: Acetates; Animals; Arthritis, Rheumatoid; Biomarkers; Cyclopropanes; Cytokines; Leukotriene Antagonists; Leukotrienes; Oxidative Stress; Quinolines; Rats; Rats, Wistar; Receptors, Leukotriene; Sulfides | 2019 |
Cysteinyl leukotriene receptor type 1 antagonist montelukast protects against injury of blood-brain barrier.
Topics: Acetates; Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Cell Line; Cyclopropanes; Endothelial Cells; Humans; Interleukin-1beta; Interleukin-6; Leukotriene Antagonists; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Quinolines; Receptors, Leukotriene; Sulfides; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Tumor Necrosis Factor-alpha | 2019 |
Montelukast Prevents Early Diabetic Retinopathy in Mice.
Topics: Acetates; Animals; Capillary Permeability; Cyclopropanes; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Electroretinography; Inflammation; Leukotriene Antagonists; Male; Mice; Quinolines; Retina; Retinal Vessels; Sulfides; Superoxides; Treatment Outcome | 2019 |
Concomitant bilastine and montelukast as additive therapy for seasonal allergic rhinoconjunctivits and mild-to-moderate asthma. The SKY study.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Benzimidazoles; Cyclopropanes; Humans; Piperidines; Quinolines; Seasons; Sulfides | 2020 |
Comparative effectiveness of budesonide inhalation suspension and montelukast in children with mild asthma in Korea.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma; Budesonide; Child; Child, Preschool; Cyclopropanes; Drug Costs; Female; Humans; Male; Medication Adherence; Office Visits; Patient Acceptance of Health Care; Quinolines; Republic of Korea; Retrospective Studies; Sulfides; Suspensions; Symptom Flare Up; Time Factors; Treatment Outcome | 2020 |
Montelukast modifies simvastatin-induced myopathy and hepatotoxicity.
Topics: Acetates; Albumins; Animals; Bilirubin; Chemical and Drug Induced Liver Injury; Creatine Kinase; Cyclopropanes; Drug Interactions; Globulins; Liver Function Tests; Male; Muscular Diseases; Myoglobin; Quinolines; Rats; Simvastatin; Sulfides | 2019 |
Efficacy of montelukast for the treatment of pediatric allergic purpura.
Topics: Acetates; Child; Cyclopropanes; Female; Humans; IgA Vasculitis; Male; Quinolines; Research Design; Sulfides; Systematic Reviews as Topic; Treatment Outcome | 2019 |
Montelukast promotes mitochondrial biogenesis via CREB/PGC-1α in human bronchial epithelial cells.
Topics: Acetates; Bronchi; Cyclic AMP Response Element-Binding Protein; Cyclopropanes; DNA-Binding Proteins; Epithelial Cells; Gene Expression Regulation; Humans; Mitochondrial Proteins; Nuclear Respiratory Factor 1; Organelle Biogenesis; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Quinolines; Signal Transduction; Sulfides; Transcription Factors | 2019 |
Effects of montelukast sodium plus budesonide on lung function, inflammatory factors, and immune levels in elderly patients with asthma.
Topics: Acetates; Aged; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Budesonide; Cyclopropanes; Female; Humans; Inflammation; Male; Middle Aged; Quinolines; Respiratory Function Tests; Sulfides | 2020 |
The effect of pulmonary surfactant on the airway smooth muscle after lipopolysaccharide exposure and its mechanisms.
Topics: Acetates; Animals; Cyclopropanes; Guinea Pigs; Lipopolysaccharides; Male; Muscle Relaxation; Muscle, Smooth; Pulmonary Surfactants; Pyrilamine; Quinolines; Sulfides | 2019 |
Corticosteroid reduction by addition of cetirizine and montelukast in biopsy-proven minimal-change nephrotic syndrome concomitant with allergic disorders.
Topics: Acetates; Adrenal Cortex Hormones; Adult; Aged; Cetirizine; Cyclopropanes; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Hypersensitivity; Immunosuppressive Agents; Leukotriene Antagonists; Male; Middle Aged; Nephrosis, Lipoid; Prednisolone; Propensity Score; Quinolines; Retrospective Studies; Sulfides; Treatment Outcome; Young Adult | 2020 |
Comparison of the Effects of Acellular Dermal Matrix and Montelukast on Radiation-Induced Peri-implant Capsular Formation in Rabbits.
Topics: Acellular Dermis; Acetates; Animals; Breast Implantation; Breast Implants; Cyclopropanes; Implant Capsular Contracture; Quinolines; Rabbits; Sulfides | 2020 |
Pediatric Drug Labeling and Imperfect Information.
Topics: Acetates; Advisory Committees; Bioethics; Cyclopropanes; Drug Labeling; Humans; Oxymorphone; Pediatrics; Quinolines; Sulfides; United States; United States Food and Drug Administration | 2020 |
The Leukotriene Receptor Antagonist Montelukast Reduces Alpha-Synuclein Load and Restores Memory in an Animal Model of Dementia with Lewy Bodies.
Topics: Acetates; alpha-Synuclein; Animals; Cyclopropanes; Disease Models, Animal; Female; Humans; Leukotriene Antagonists; Lewy Body Disease; Memory; Memory Disorders; Mice; Mice, Transgenic; Quinolines; Receptors, Leukotriene; Sulfides | 2020 |
Potential synergistic effects of novel hematopoietic prostaglandin D synthase inhibitor TAS-205 and different types of anti-allergic medicine on nasal obstruction in a Guinea pig model of experimental allergic rhinitis.
Topics: Acetates; Animals; Anti-Allergic Agents; Cell Line; Cyclopropanes; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Guinea Pigs; Humans; Intramolecular Oxidoreductases; Lipocalins; Male; Morpholines; Nasal Mucosa; Nasal Obstruction; Ovalbumin; Piperidines; Prostaglandin D2; Pyrroles; Quality of Life; Quinolines; Rats; Rhinitis, Allergic; Sulfides; Terfenadine | 2020 |
Montelukast ameliorates doxorubicin-induced cardiotoxicity via modulation of p-glycoprotein and inhibition of ROS-mediated TNF-α/NF-κB pathways.
Topics: Acetates; Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cardiotoxicity; Cyclopropanes; Doxorubicin; Male; Myocardium; NF-kappa B; Oxidative Stress; Quinolines; Rats; Rats, Wistar; Reactive Oxygen Species; Sulfides; Tumor Necrosis Factor-alpha | 2022 |
Montelukast ameliorates Concanavalin A-induced autoimmune hepatitis in mice via inhibiting TNF-α/JNK signaling pathway.
Topics: Acetates; Animals; Apoptosis; Autophagy; Concanavalin A; Cyclopropanes; Hepatitis, Autoimmune; Interleukin-6; Leukotriene Antagonists; Liver; Liver Function Tests; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Oxidative Stress; Quinolines; Sulfides; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2020 |
Radioprotective effects of montelukast, a selective leukotriene CysLT1 receptor antagonist, against nephrotoxicity induced by gamma radiation in mice.
Topics: Acetates; Animals; Antioxidants; Creatinine; Cyclopropanes; Gamma Rays; Glutathione; Kidney; Leukotriene Antagonists; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Quinolines; Radiation-Protective Agents; Radiotherapy; Receptors, Leukotriene; Renal Insufficiency; Sulfides | 2020 |
Mechanisms underlying the protective effect of leukotriene receptor antagonist montelukast against doxorubicin induced testicular injury in rats.
Topics: Acetates; Animals; Caspase 3; Cyclopropanes; Cytoprotection; Doxorubicin; Gene Expression Regulation, Enzymologic; Leukotriene Antagonists; Male; Matrix Metalloproteinase 9; Organ Size; Oxidative Stress; PPAR gamma; Quinolines; Rats; Rats, Wistar; Receptors, Leukotriene; Spermatogenesis; Sulfides; Testis; Tumor Necrosis Factor-alpha | 2020 |
Cysteinyl Leukotriene Synthesis via Phospholipase A2 Group IV Mediates Exercise-induced Bronchoconstriction and Airway Remodeling.
Topics: Acetates; Airway Remodeling; Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Cyclopropanes; Cysteine; Female; Group II Phospholipases A2; Leukotrienes; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Physical Conditioning, Animal; Quinolines; Respiratory Hypersensitivity; Sulfides | 2020 |
Premedication with montelukast and rupatadine decreased rituximab infusion time, rate, severity of reactions and use of rescue medications.
Topics: Acetaminophen; Acetates; Adult; Aged; Aged, 80 and over; Cyclopropanes; Cyproheptadine; Diphenhydramine; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Lymphoproliferative Disorders; Male; Middle Aged; Premedication; Quinolines; Rituximab; Standard of Care; Sulfides; Treatment Outcome | 2020 |
The Novel Potential Therapeutic Utility of Montelukast in Alleviating Autistic Behavior Induced by Early Postnatal Administration of Thimerosal in Mice.
Topics: Acetates; alpha7 Nicotinic Acetylcholine Receptor; Animals; Animals, Newborn; Autistic Disorder; Cyclopropanes; Growth and Development; Hippocampus; Mice; Nerve Tissue Proteins; Quinolines; Social Behavior; Sulfides; Thimerosal; Transcription Factor RelA | 2021 |
Alpha-1 Antitrypsin Deficiency and Pregnancy.
Topics: Acetates; Adult; alpha 1-Antitrypsin; alpha 1-Antitrypsin Deficiency; Anti-Asthmatic Agents; Budesonide, Formoterol Fumarate Drug Combination; Cyclopropanes; Female; Forced Expiratory Volume; Humans; Panniculitis; Phenotype; Pregnancy; Pregnancy Complications; Pulmonary Diffusing Capacity; Pulmonary Emphysema; Quinolines; Spirometry; Sulfides; Trypsin Inhibitors | 2020 |
Identification of cysteinyl-leukotriene-receptor 1 antagonists as ligands for the bile acid receptor GPBAR1.
Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile Acids and Salts; Colitis; Cyclopropanes; Disease Models, Animal; Gene Expression; Genes, Reporter; HEK293 Cells; Hep G2 Cells; Humans; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Luciferases; Mice; Mice, Knockout; Molecular Docking Simulation; Quinolines; RAW 264.7 Cells; Receptors, G-Protein-Coupled; Receptors, Leukotriene; Recombinant Fusion Proteins; Sulfides | 2020 |
Montelukast, a cysteinyl leukotriene receptor antagonist, exerts local antinociception in animal model of pain through the L-arginine/nitric oxide/cyclic GMP/K
Topics: Acetates; Analgesia; Analgesics; Animals; Arginine; Behavior, Animal; Cyclic GMP; Cyclopropanes; Disease Models, Animal; KATP Channels; Leukotriene Antagonists; Male; Nitric Oxide; Nociceptive Pain; PPAR gamma; Quinolines; Rats, Wistar; Signal Transduction; Sulfides | 2021 |
As a potential treatment of COVID-19: Montelukast.
Topics: Acetates; Anti-Inflammatory Agents; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Cyclopropanes; Cytokines; Disease Progression; Humans; Inflammation; Oxidative Stress; Pandemics; Pneumonia, Viral; Quinolines; Receptors, Leukotriene; SARS-CoV-2; Sulfides | 2020 |
Clinical course of asthma in 4 cases of coronavirus disease 2019 infection.
Topics: Acetates; Adult; Albuterol; Anti-Asthmatic Agents; Asthma; Betacoronavirus; Black or African American; Coronavirus Infections; COVID-19; Cyclopropanes; Dyspnea; Female; Histamine Antagonists; Humans; Lung; Male; Pandemics; Pneumonia, Viral; Quinolines; SARS-CoV-2; Severity of Illness Index; Sulfides | 2020 |
Targeting E. coli invasion of the blood-brain barrier for investigating the pathogenesis and therapeutic development of E. coli meningitis.
Topics: Acetates; Animals; Anti-Bacterial Agents; Blood-Brain Barrier; Brain; Ceftriaxone; Cells, Cultured; Cyclopropanes; Cysteine; Drug Therapy, Combination; Endothelial Cells; ErbB Receptors; Escherichia coli; Female; Gefitinib; Humans; Infant, Newborn; Leukotriene Antagonists; Leukotrienes; Male; Meningitis, Escherichia coli; Mice; Permeability; Phospholipases A2, Cytosolic; Quinolines; Sphingosine-1-Phosphate Receptors; Sulfides | 2020 |
The association between obesity and poor outcome after COVID-19 indicates a potential therapeutic role for montelukast.
Topics: Acetates; Antiviral Agents; Betacoronavirus; Coronavirus 3C Proteases; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Cyclopropanes; Cysteine Endopeptidases; Cytokine Release Syndrome; Drug Repositioning; Humans; Immunologic Factors; Inflammation; Leukotriene Antagonists; Obesity; Pandemics; Pneumonia, Viral; Quinolines; SARS-CoV-2; Sulfides; Viral Nonstructural Proteins | 2020 |
lncRNA PCGEM1 strengthens anti-inflammatory and lung protective effects of montelukast sodium in children with cough-variant asthma.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cough; Cyclopropanes; Disease Models, Animal; Female; Humans; Male; Mice; Mice, Inbred BALB C; Protective Agents; Quinolines; RNA, Long Noncoding; Sulfides | 2020 |
COVID-19, severe asthma, and biologics.
Topics: Acetates; Adrenergic beta-2 Receptor Antagonists; Amoxicillin-Potassium Clavulanate Combination; Anti-Asthmatic Agents; Antibodies, Monoclonal, Humanized; Asthma; Azithromycin; Betacoronavirus; Budesonide; Convalescence; Coronavirus Infections; COVID-19; Cyclopropanes; Eosinophils; Female; Humans; Hydroxychloroquine; Ipratropium; Male; Middle Aged; Pandemics; Pneumonia, Viral; Quinolines; SARS-CoV-2; Sulfides; Treatment Outcome | 2020 |
In brief: Neuropsychiatric events with montelukast.
Topics: Acetates; Anti-Asthmatic Agents; Cyclopropanes; Humans; Leukotriene Antagonists; Neurotoxicity Syndromes; Quinolines; Suicide; Sulfides | 2020 |
Montelukast's ability to fight COVID-19 infection.
Topics: Acetates; Aged; Aged, 80 and over; Anti-Asthmatic Agents; Asthma; Case-Control Studies; COVID-19; COVID-19 Serological Testing; Cyclopropanes; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; SARS-CoV-2; Sulfides | 2021 |
New Boxed Warning for Singulair.
Topics: Acetates; Anti-Asthmatic Agents; Cyclopropanes; Drug Labeling; Humans; Mood Disorders; Quinolines; Sulfides; United States; United States Food and Drug Administration | 2020 |
Exploration of therapeutic role of montelukast and dexamethasone combination against paraquat induced inhalational toxicity.
Topics: Acetates; Acute Lung Injury; Administration, Inhalation; Animals; Anti-Inflammatory Agents; Catalase; Cyclopropanes; Cytokines; Dexamethasone; Drug Therapy, Combination; Glutathione Peroxidase; Herbicides; Lung; Male; NF-kappa B; Paraquat; Quinolines; Rats, Wistar; Respiratory Function Tests; Sulfides; Superoxide Dismutase | 2020 |
Montelukast drug activity and potential against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Topics: Acetates; Anti-Inflammatory Agents; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Cyclopropanes; Humans; Quinolines; SARS-CoV-2; Sulfides | 2021 |
Evaluation of Montelukast for the Prevention of Infusion-related Reactions With Daratumumab.
Topics: Acetates; Antibodies, Monoclonal; Antineoplastic Agents; Cyclopropanes; Cytochrome P-450 CYP1A2 Inducers; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Quinolines; Sulfides | 2020 |
Fabrication of Montelukast sodium loaded filaments and 3D printing transdermal patches onto packaging material.
Topics: Acetates; Cyclopropanes; Drug Liberation; Printing, Three-Dimensional; Quinolines; Sulfides | 2020 |
Effective treatment of eosinophilic dermatosis of haematological malignancy with montelukast.
Topics: Acetates; Cyclopropanes; Eosinophils; Hematologic Neoplasms; Humans; Paraneoplastic Syndromes; Quinolines; Skin Diseases; Sulfides; Treatment Outcome | 2021 |
Montelukast in children with allergic rhinitis amid COVID-19 pandemic.
Topics: Acetates; Child; COVID-19; Cyclopropanes; Humans; Pandemics; Quinolines; Rhinitis, Allergic; SARS-CoV-2; Sulfides | 2020 |
Montelukast improves bronchopulmonary dysplasia by inhibiting epithelial‑mesenchymal transition via inactivating the TGF‑β1/Smads signaling pathway.
Topics: Acetates; Alveolar Epithelial Cells; Animals; Bronchopulmonary Dysplasia; Cell Hypoxia; Cyclopropanes; Disease Models, Animal; Epithelial-Mesenchymal Transition; Gene Expression Regulation; Quinolines; Rats; Signal Transduction; Smad Proteins; Sulfides; Transforming Growth Factor beta1 | 2020 |
Eosinophilic gastroenteritis treated with a targeted food elimination diet.
Topics: Acetates; Anti-Allergic Agents; Arylsulfonates; Child; Cyclopropanes; Diarrhea; Diet; Enteritis; Eosinophilia; Food Hypersensitivity; Gastritis; Humans; Male; Quinolines; Sulfides; Sulfonium Compounds; Terfenadine; Treatment Outcome | 2020 |
AERD Associated Nasal Polyposis: Efficacy of Postoperative Antileukotriene Therapy in Comparison with Aspirin Desensitization. A Retrospective Study.
Topics: Acetates; Adult; Aged; Allergens; Aspirin; Asthma, Aspirin-Induced; Cyclopropanes; Desensitization, Immunologic; Endoscopy; Follow-Up Studies; Humans; Leukotriene Antagonists; Middle Aged; Nasal Polyps; Postoperative Period; Quality of Life; Quinolines; Retrospective Studies; Rhinoplasty; Sulfides; Treatment Outcome | 2020 |
Risk of Psychiatric Adverse Events Among Montelukast Users.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Drug Therapy, Combination; Humans; Quinolines; Sulfides | 2021 |
Steroid-dependent Kimura Disease in a Child Treated with Cetirizine and Montelukast.
Topics: Acetates; Cetirizine; Child; Cyclopropanes; Double-Blind Method; Humans; Kimura Disease; Quinolines; Steroids; Sulfides | 2020 |
Comparison of adherence measures using claims data in the South African private health sector.
Topics: Acetates; Administrative Claims, Healthcare; Anti-Asthmatic Agents; Cross-Sectional Studies; Cyclopropanes; Humans; Mathematical Concepts; Medication Adherence; Quinolines; Retrospective Studies; South Africa; Sulfides | 2020 |
Sarcoidosis exosomes stimulate monocytes to produce pro-inflammatory cytokines and CCL2.
Topics: Acetates; Adult; Bronchoalveolar Lavage Fluid; Case-Control Studies; Chemokine CCL2; Cyclopropanes; Cytokines; Exosomes; Female; Humans; Interleukin-1beta; Male; Middle Aged; Monocytes; Quinolines; Reactive Oxygen Species; Sarcoidosis, Pulmonary; Sulfides | 2020 |
Taming the cytokine storm: repurposing montelukast for the attenuation and prophylaxis of severe COVID-19 symptoms.
Topics: Acetates; Age Factors; COVID-19; COVID-19 Drug Treatment; Cyclopropanes; Cytokine Release Syndrome; Cytokines; Drug Repositioning; Humans; Leukotriene Antagonists; NF-kappa B; Obesity; Quinolines; Respiratory Distress Syndrome; Severity of Illness Index; Sex Factors; Signal Transduction; Sulfides | 2020 |
To Maintain Formulation Composition Similarity of Coated Tablets of Different Strengths: Should Coating be Based on Core Tablet Weight or Surface Area?
Topics: Acetates; Chemistry, Pharmaceutical; Cyclopropanes; Drug Compounding; Drug Stability; Humans; Nifedipine; Photophobia; Quinolines; Rosuvastatin Calcium; Sulfides; Tablets | 2020 |
Leukotrienes, a potential target for Covid-19.
Topics: Acetates; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Betacoronavirus; Coronavirus Infections; COVID-19; Cyclopropanes; Cytokine Release Syndrome; Humans; Hydroxyurea; Immunologic Factors; Indoles; Leukotrienes; Pandemics; Phenylcarbamates; Pneumonia, Viral; Quinolines; SARS-CoV-2; Severity of Illness Index; Sulfides; Sulfonamides; Tosyl Compounds | 2020 |
Cost-effectiveness analysis of double low-dose budesonide and low-dose budesonide plus montelukast among pediatric patients with persistent asthma receiving Step 3 treatment in China.
Topics: Acetates; Administration, Inhalation; Anti-Asthmatic Agents; Asthma; Budesonide; Child; China; Cost-Benefit Analysis; Cyclopropanes; Drug Therapy, Combination; Humans; Quinolines; Sulfides | 2020 |
Montelukast-Based Premedication Regimen for Recurrent Cetuximab Infusion-Related Reactions.
Topics: Acetates; Cetuximab; Cyclopropanes; Humans; Premedication; Quinolines; Sulfides | 2021 |
A possible effect of montelukast on neurological aging examined by the use of register data.
Topics: Acetates; Aged; Aging; Animals; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Rats; Sulfides | 2021 |
In Vivo Predictive Dissolution Testing of Montelukast Sodium Formulations Administered with Drinks and Soft Foods to Infants.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Area Under Curve; Beverages; Cyclopropanes; Drug Compounding; Fasting; Food; Humans; Infant; Milk; Pharmaceutical Vehicles; Quinolines; Solubility; Sulfides | 2020 |
A simple and sensitive HPLC-MS/MS assay for the quantitation of montelukast in cell-based systems in vitro pulmonary drug permeability study.
Topics: Acetates; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cyclopropanes; Germany; Lung; Permeability; Pharmaceutical Preparations; Quinolines; Reproducibility of Results; Sulfides; Tandem Mass Spectrometry | 2021 |
Co-electrospraying technology as a novel approach for dry powder inhalation formulation of montelukast and budesonide for pulmonary co-delivery.
Topics: Acetates; Administration, Inhalation; Aerosols; Budesonide; Cyclopropanes; Dry Powder Inhalers; Humans; Lung; Particle Size; Powders; Quinolines; Sulfides; Technology | 2020 |
Impact of Food and Drink Administration Vehicles on Paediatric Formulation Performance Part 2: Dissolution of Montelukast Sodium and Mesalazine Formulations.
Topics: Acetates; Administration, Oral; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Beverages; Biological Availability; Child; Cyclopropanes; Drug Compounding; Drug Liberation; Excipients; Food; Humans; Infant; Mesalamine; Pediatrics; Pharmaceutical Vehicles; Quinolines; Solubility; Sulfides | 2020 |
The examination of the nephroprotective effect of montelukast sodium and N-acetylcysteine ın renal ıschemia with dimercaptosuccinic acid imaging in a placebo-controlled rat model.
Topics: Acetates; Acetylcysteine; Animals; Cyclopropanes; Kidney; Quinolines; Rats; Rats, Wistar; Reperfusion Injury; Succimer; Sulfides; Tomography, X-Ray Computed | 2020 |
Montelukast does not increase the risk of attention-deficit/hyperactivity disorder in pediatric asthma patients: A nationwide population-based matched cohort study.
Topics: Acetates; Asthma; Attention Deficit Disorder with Hyperactivity; Child; Cohort Studies; Cyclopropanes; Humans; Prospective Studies; Quinolines; Retrospective Studies; Risk Factors; Sulfides; Taiwan | 2021 |
Formation of a Thiol-Ene Addition Product of Asthma Medication Montelukast Caused by a Widespread Tin-Based Thermal Stabilizer.
Topics: Acetates; Asthma; Cyclopropanes; Humans; Molecular Structure; Organotin Compounds; Quinolines; Sulfhydryl Compounds; Sulfides; Temperature | 2020 |
Effectiveness of montelukast for uremic pruritus in hemodialysis patients: A protocol for systematic review and meta-analysis.
Topics: Acetates; Clinical Protocols; Cyclopropanes; Humans; Kidney Failure, Chronic; Leukotriene Antagonists; Meta-Analysis as Topic; Pruritus; Quinolines; Renal Dialysis; Sulfides; Systematic Reviews as Topic | 2020 |
Effect of Montelukast Sodium and Graphene Oxide Nanomaterials on Mouse Asthma Model.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Graphite; Humans; Mice; Nanostructures; Quinolines; Sulfides | 2021 |
Reposition of montelukast either alone or in combination with levocetirizine against SARS-CoV-2.
Topics: Acetates; Anti-Asthmatic Agents; Antiviral Agents; Cetirizine; Clinical Trials as Topic; COVID-19 Drug Treatment; Cyclopropanes; Drug Repositioning; Histamine H1 Antagonists, Non-Sedating; Humans; Hypersensitivity; Models, Theoretical; Patient Safety; Quinolines; Sulfides; Taste | 2020 |
[What is the role of montelukast in asthma treatment?]
Topics: Acetates; Administration, Inhalation; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Glucocorticoids; Humans; Patient Compliance; Quinolines; Sulfides | 2020 |
Development of LC-MS/MS method and application to bioequivalence study of a light sensitive drug montelukast.
Topics: Acetates; Chromatography, Liquid; Cyclopropanes; Humans; Pharmaceutical Preparations; Quinolines; Reproducibility of Results; Sulfides; Tandem Mass Spectrometry; Therapeutic Equivalency | 2021 |
Antiviral activity against Middle East Respiratory Syndrome coronavirus by Montelukast, an anti-asthma drug.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Antiviral Agents; Carrier Proteins; Chlorocebus aethiops; Coronavirus Infections; Cyclopropanes; Cytochrome P-450 CYP1A2 Inducers; Dipeptidyl Peptidase 4; Drug Repositioning; HEK293 Cells; Humans; Leukotriene Antagonists; Middle East Respiratory Syndrome Coronavirus; Quinolines; Receptors, Virus; Spike Glycoprotein, Coronavirus; Sulfides; Vero Cells; Virus Internalization | 2021 |
Efficacy and safety of montelukast sodium combined with fluticasone in the treatment of adult bronchial asthma: A protocol for systematic review and meta-analysis.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Cyclopropanes; Drug Combinations; Fluticasone; Humans; Meta-Analysis as Topic; Quinolines; Research Design; Sulfides; Systematic Reviews as Topic; Treatment Outcome | 2020 |
FDA Boxed Warning for Montelukast: Impact on Adult Severe Asthmatics?
Topics: Acetates; Adult; Cyclopropanes; Drug Labeling; Humans; Quinolines; Sulfides; United States | 2020 |
Montelukast alleviates inflammation in experimental autoimmune encephalomyelitis by altering Th17 differentiation in a mouse model.
Topics: Acetates; Adoptive Transfer; Animals; Anti-Inflammatory Agents; Cell Differentiation; Cyclopropanes; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Humans; Inflammation; Leukotriene Antagonists; Mice; Mice, Inbred C57BL; Molecular Targeted Therapy; Multiple Sclerosis; Quinolines; Receptors, Leukotriene; Signal Transduction; Sulfides; Th17 Cells | 2021 |
The Effect of Oral Montelukast Administration in Cholesteatoma Development and Inflammation: An Experimental Animal Model.
Topics: Acetates; Animals; Cholesteatoma, Middle Ear; Cyclopropanes; Female; Inflammation; Models, Animal; Quinolines; Rats; Rats, Wistar; Sulfides | 2021 |
Ameliorating effect of leukotriene receptor antagonist in multi-organ toxicity induced in rat offspring, a possible role for epidermal growth factor.
Topics: Acetates; Animals; Calcification, Physiologic; Cyclopropanes; Epidermal Growth Factor; Female; Kidney; Leukotriene Antagonists; Male; Metal Nanoparticles; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Leukotriene; Silver; Sulfides | 2021 |
Efficacy and safety of montelukast for pediatric obstructive sleep apnea syndrome: A protocol for systematic review and meta-analysis.
Topics: Acetates; Anti-Asthmatic Agents; Child; Clinical Protocols; Cyclopropanes; Humans; Meta-Analysis as Topic; Polysomnography; Quinolines; Sleep Apnea, Obstructive; Sulfides; Systematic Reviews as Topic | 2021 |
Dipyridamole, chloroquine, montelukast sodium, candesartan, oxytetracycline, and atazanavir are not SARS-CoV-2 main protease inhibitors.
Topics: Acetates; Atazanavir Sulfate; Benzimidazoles; Biphenyl Compounds; Chloroquine; COVID-19 Drug Treatment; Cyclopropanes; Dipyridamole; Humans; Oxytetracycline; Pharmaceutical Preparations; Protease Inhibitors; Quinolines; SARS-CoV-2; Sulfides; Tetrazoles | 2021 |
Reply to Ma and Wang: Reliability of various in vitro activity assays on SARS-CoV-2 main protease inhibitors.
Topics: Acetates; Atazanavir Sulfate; Benzimidazoles; Biphenyl Compounds; Chloroquine; COVID-19 Drug Treatment; Cyclopropanes; Dipyridamole; Humans; Oxytetracycline; Protease Inhibitors; Quinolines; Reproducibility of Results; SARS-CoV-2; Sulfides; Tetrazoles | 2021 |
Montelukast in hospitalized patients diagnosed with COVID-19.
Topics: Acetates; Asthma; Clinical Deterioration; COVID-19 Drug Treatment; Cyclopropanes; Humans; Leukotriene Antagonists; Prospective Studies; Quinolines; Retrospective Studies; SARS-CoV-2; Sulfides; Treatment Outcome | 2022 |
Effectiveness of a multidrug therapy consisting of Ivermectin, Azithromycin, Montelukast, and Acetylsalicylic acid to prevent hospitalization and death among ambulatory COVID-19 cases in Tlaxcala, Mexico.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Antiviral Agents; Aspirin; Azithromycin; COVID-19 Drug Treatment; Cyclopropanes; Drug Therapy, Combination; Hospitalization; Humans; Ivermectin; Male; Mexico; Middle Aged; Quinolines; SARS-CoV-2; Sulfides; Treatment Outcome; Young Adult | 2021 |
The Leukotriene Receptor Antagonist Montelukast Attenuates Neuroinflammation and Affects Cognition in Transgenic 5xFAD Mice.
Topics: Acetates; Alzheimer Disease; Animals; Brain; CD8-Positive T-Lymphocytes; Cognition; Cyclopropanes; Inflammation; Leukotriene Antagonists; Mice; Mice, Transgenic; Quinolines; Sulfides | 2021 |
The relevance of CYSLTR1 gene polymorphism to the severity of allergic rhinitis and clinical responsiveness of montelukast in children.
Topics: Acetates; Anti-Asthmatic Agents; Child; Cyclopropanes; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Polymorphism, Single Nucleotide; Quinolines; Receptors, Leukotriene; Rhinitis, Allergic; Sulfides | 2021 |
Modulation of autophagy and transient receptor potential vanilloid 4 channels by montelukast in a rat model of hemorrhagic cystitis.
Topics: Acetates; Animals; Apoptosis; Autophagy; Cyclophosphamide; Cyclopropanes; Cystitis; Hemorrhage; Inflammation; Male; Mast Cells; Mesna; Oxidative Stress; Phagocytosis; Phagosomes; Quinolines; Rats; Signal Transduction; Sulfides; TRPV Cation Channels; Urinary Bladder; Urothelium | 2021 |
Clinical analysis of montelukast combined with Pumike Aerosol in the treatment of infantile asthma.
Topics: Acetates; Aerosols; Asthma; Cyclopropanes; Humans; Quinolines; Sulfides | 2022 |
The therapeutic role of lactobacillus and montelukast in combination with metformin in diabetes mellitus complications through modulation of gut microbiota and suppression of oxidative stress.
Topics: Acetates; Animals; Cyclopropanes; Cytochrome P-450 CYP1A2 Inducers; Diabetes Complications; Diabetes Mellitus, Experimental; Disease Models, Animal; Drug Therapy, Combination; Gastrointestinal Microbiome; Hypoglycemic Agents; Inflammation; Lactobacillus; Male; Metformin; Oxidative Stress; Quinolines; Rats; Rats, Sprague-Dawley; Sulfides | 2021 |
A New Workflow for Drug Metabolite Profiling by Utilizing Advanced Tribrid Mass Spectrometry and Data-Processing Techniques.
Topics: Acetates; Buspirone; Chromatography, Liquid; Cyclopropanes; Data Mining; Electronic Data Processing; Equipment Design; Metabolomics; Microsomes, Liver; Pharmaceutical Preparations; Quinolines; Sulfides; Tandem Mass Spectrometry; Ticlopidine; Timolol; Workflow | 2021 |
Lower Limb Bruising Associated with Montelukast in an Asthmatic Child.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Humans; Lower Extremity; Quinolines; Sulfides | 2021 |
Montelukast microsuspension with hypromellose for improved stability and oral absorption.
Topics: Acetates; Administration, Oral; Animals; Crystallization; Cyclopropanes; Drug Liberation; Drug Stability; Hydrogen Bonding; Hypromellose Derivatives; Male; Quinolines; Rats; Solubility; Sulfides; Suspensions | 2021 |
Role of montelukast in multitrigger wheezers attending chest clinic in Punjab, India.
Topics: Acetates; Child, Preschool; Cyclopropanes; Humans; India; Infant; Prospective Studies; Quinolines; Sulfides | 2021 |
Evaluation of efficiency and safety of combined montelukast sodium and budesonide in children with cough variant asthma: A protocol for systematic review and meta-analysis.
Topics: Acetates; Administration, Inhalation; Asthma; Budesonide; Child; Chronic Disease; Cough; Cyclopropanes; Drug Therapy, Combination; Glucocorticoids; Humans; Leukotriene Antagonists; Meta-Analysis as Topic; Quinolines; Randomized Controlled Trials as Topic; Sulfides; Systematic Reviews as Topic; Treatment Outcome | 2021 |
Risk Assessment-Based Enhanced Analytical Quality-by-Design Approach to Eco-Friendly and Economical Multicomponent Spectrophotometric Methods for Simultaneous Estimation of Montelukast Sodium and Bilastine.
Topics: Acetates; Benzimidazoles; Cyclopropanes; Piperidines; Quinolines; Risk Assessment; Sulfides | 2021 |
Ecotoxicity and photodegradation of Montelukast (a drug to treat asthma) in water.
Topics: Acetates; Animals; Asthma; Cyclopropanes; Daphnia; Pharmaceutical Preparations; Photolysis; Quinolines; Sulfides; Water; Water Pollutants, Chemical | 2021 |
Case Study 5: Predicting the Drug Interaction Potential for Inhibition of CYP2C8 by Montelukast.
Topics: Acetates; Area Under Curve; Cyclopropanes; Cytochrome P-450 CYP2C8; Drug Interactions; Humans; Kinetics; Plasma; Quinolines; Rosiglitazone; Sulfides | 2021 |
[Adverse drug reactions of montelukast: from theory to practice. Case report].
Topics: Acetates; Anti-Asthmatic Agents; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Humans; Quinolines; Retrospective Studies; Sulfides | 2021 |
Montelukast potentiates the antiinflammatory effect of NSAIDs in the rat paw formalin model and simultaneously minimizes the risk of gastric damage.
Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclopropanes; Diclofenac; Formaldehyde; Inflammation; Male; Nitric Oxide Synthase Type II; Quinolines; Rats; Rats, Wistar; Risk; Signal Transduction; Stomach; Sulfides | 2021 |
Risk and DoE-Based Analytical Failure Mode Effect Analysis (AFMEA) to Simultaneous Estimation of Montelukast Sodium and Bilastine by HPTLC Method Using Enhanced AQbD Approach.
Topics: Acetates; Benzimidazoles; Chromatography, Thin Layer; Cyclopropanes; Humans; Piperidines; Quinolines; Research Design; Sulfides | 2022 |
Fabrication of pure-drug microneedles for delivery of montelukast sodium.
Topics: Acetates; Administration, Cutaneous; Animals; Cyclopropanes; Drug Delivery Systems; Needles; Pharmaceutical Preparations; Quinolines; Skin; Solvents; Sulfides; Swine | 2022 |
LTA4H rs2660845 association with montelukast response in early and late-onset asthma.
Topics: Acetates; Adolescent; Adult; Age of Onset; Alleles; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cross-Sectional Studies; Cyclopropanes; Epoxide Hydrolases; Europe; Female; Genotype; Hospitalization; Humans; Leukotriene Antagonists; Longitudinal Studies; Male; Middle Aged; Odds Ratio; Pharmacogenetics; Quinolines; Regression Analysis; Risk; Sulfides; Young Adult | 2021 |
Montelukast attenuates interleukin IL-1β-induced oxidative stress and apoptosis in chondrocytes by inhibiting CYSLTR1 (Cysteinyl Leukotriene Receptor 1) and activating KLF2 (Kruppel Like Factor 2).
Topics: Acetates; Animals; Apoptosis; Chondrocytes; Cyclopropanes; Interleukin-1beta; Kruppel-Like Transcription Factors; Mice; Oxidative Stress; Quinolines; Receptors, Leukotriene; Signal Transduction; Sulfides | 2021 |
Treatment of pediatric mild persistent asthma with low-dose budesonide inhalation suspension vs. montelukast in China.
Topics: Acetates; Administration, Inhalation; Adolescent; Anti-Asthmatic Agents; Asthma; Budesonide; Child; Child, Preschool; China; Cyclopropanes; Humans; Quinolines; Retrospective Studies; Sulfides | 2021 |
Retained strength of expired albuterol and montelukast pharmaceuticals.
Topics: Acetates; Albuterol; Anti-Asthmatic Agents; Bronchodilator Agents; Cyclopropanes; Double-Blind Method; Humans; Pharmaceutical Preparations; Quinolines; Salmeterol Xinafoate; Sulfides | 2022 |
The neutralization effect of montelukast on SARS-CoV-2 is shown by multiscale in silico simulations and combined in vitro studies.
Topics: A549 Cells; Acetates; Angiotensin-Converting Enzyme 2; Animals; Cell Survival; Chlorocebus aethiops; Cyclopropanes; Drug Repositioning; HEK293 Cells; Humans; Models, Molecular; Molecular Docking Simulation; Molecular Structure; Neutralization Tests; Protein Conformation; Quinolines; SARS-CoV-2; Serine Endopeptidases; Sulfides; Vero Cells; Virus Internalization | 2022 |
Inhibition of the cysteinyl leukotriene pathways increases survival of RGCs and reduces microglial activation in ocular hypertension.
Topics: Acetates; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Biomarkers; Calcium-Binding Proteins; Cell Survival; Cyclopropanes; Disease Models, Animal; Electroretinography; Female; Gene Expression Regulation; Intraocular Pressure; Leukotriene Antagonists; Microfilament Proteins; Microglia; Microscopy, Confocal; Microscopy, Fluorescence; Ocular Hypertension; Quinolines; Rats; Rats, Inbred BN; Real-Time Polymerase Chain Reaction; Receptors, G-Protein-Coupled; Receptors, Leukotriene; Retina; Retinal Ganglion Cells; RNA, Messenger; Sulfides; Tonometry, Ocular; Transcription Factor Brn-3B | 2021 |
Involvement of GPR17 in Neuronal Fibre Outgrowth.
Topics: Acetates; Animals; Animals, Newborn; Coculture Techniques; Cyclopropanes; Drug Evaluation, Preclinical; Female; Leukotriene Antagonists; Male; Nerve Regeneration; Neuronal Outgrowth; Quinolines; Rats; Receptors, G-Protein-Coupled; Sulfides | 2021 |
The Impact of Non-Invasive Ventilation Combined with Montelukast on Clinical Efficiency and Pulmonary Function in Patients with Bronchial Asthma Complicated by Obstructive Sleep Apnea Hypopnea Syndrome.
Topics: Acetates; Asthma; Cyclopropanes; Humans; Noninvasive Ventilation; Quinolines; Sleep Apnea, Obstructive; Sulfides | 2022 |
Budesonide promotes airway epithelial barrier integrity following double-stranded RNA challenge.
Topics: Acetates; Administration, Inhalation; Animals; Asthma; Bronchi; Bronchodilator Agents; Budesonide; Cell Line; Cell Membrane Permeability; Cyclopropanes; Dextrans; Electric Impedance; Epithelial Cells; Female; Fluorescein-5-isothiocyanate; Formoterol Fumarate; Humans; Male; Mice; Mice, Inbred C57BL; Models, Biological; Molecular Mimicry; Poly I-C; Quinolines; RNA, Double-Stranded; RNA, Viral; Sulfides; Tight Junctions | 2021 |
FDA warning montelukast 03.2020-Statement of the Austrian working group of pediatric pulmonology and allergology.
Topics: Acetates; Anti-Asthmatic Agents; Austria; Child; Cyclopropanes; Humans; Infant; Pulmonary Medicine; Quinolines; Sulfides | 2022 |
Chronobiological activity of cysteinyl leukotriene receptor 1 during basal and induced autophagy in the ARPE-19 retinal pigment epithelial cell line.
Topics: Acetates; Autophagy; Blotting, Western; Cell Line; Cell Survival; Chronobiology Phenomena; Cyclopropanes; Epithelial Cells; Humans; Indoles; Leukotriene Antagonists; Oxidative Stress; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Retinal Pigment Epithelium; Sulfides; Sulfonamides | 2021 |
Simultaneous determination of febuxostat and montelukast in human plasma using fabric phase sorptive extraction and high performance liquid chromatography-fluorimetric detection.
Topics: Acetates; Adsorption; Adult; Chromatography, High Pressure Liquid; Cotton Fiber; Cyclopropanes; Febuxostat; Humans; Limit of Detection; Linear Models; Quinolines; Reproducibility of Results; Sulfides; Young Adult | 2022 |
PI3Kδ inhibition prevents IL33, ILC2s and inflammatory eosinophils in persistent airway inflammation.
Topics: Acetates; Animals; Antigens, Dermatophagoides; Class I Phosphatidylinositol 3-Kinases; Cyclopropanes; Cytokines; Eosinophils; Female; Goblet Cells; Hypersensitivity; Inflammation; Interleukin-33; Interleukin-5; Lymphocytes; Mice; Mice, Inbred BALB C; Pyroglyphidae; Quinolines; Respiratory System; Sulfides; Th2 Cells | 2021 |
Therapeutic effect of acupuncture combined montelukast sodium on cough variant asthma in children: A protocol for systematic review and meta-analysis.
Topics: Acetates; Acupuncture Therapy; Anti-Asthmatic Agents; Asthma; Child; Combined Modality Therapy; Cough; Cyclopropanes; Humans; Meta-Analysis as Topic; Quinolines; Research Design; Sulfides; Systematic Reviews as Topic; Treatment Outcome | 2021 |
Levocetirizine and montelukast in the COVID-19 treatment paradigm.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Cetirizine; Child; Child, Preschool; COVID-19 Drug Treatment; Cyclopropanes; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Retrospective Studies; SARS-CoV-2; Sulfides; Treatment Outcome; Young Adult | 2022 |
Relationship between montelukast and behavioral problems in preschool children with asthma.
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Child, Preschool; Cyclopropanes; Drug Therapy, Combination; Hallucinations; Humans; Infant; Problem Behavior; Quinolines; Sulfides | 2022 |
Montelukast and neuropsychiatric events - a sequence symmetry analysis.
Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Humans; Quinolines | 2022 |
Performance Evaluation of Montelukast Pediatric Formulations: Part II - a PBPK Modelling Approach.
Topics: Acetates; Administration, Oral; Adolescent; Adult; Age Factors; Anti-Asthmatic Agents; Biopharmaceutics; Chemistry, Pharmaceutical; Child; Child, Preschool; Computer Simulation; Cyclopropanes; Drug Development; Drug Liberation; Female; Humans; Infant; Male; Models, Biological; Pediatrics; Quinolines; Solubility; Sulfides; Young Adult | 2022 |
Montelukast suppresses the development of irritable bowel syndrome phenotype possibly through modulating NF-κB signaling in an experimental model.
Topics: Acetates; Acetic Acid; Animals; Cyclopropanes; Irritable Bowel Syndrome; Models, Theoretical; NF-kappa B; Phenotype; Quinolines; Rats; Sulfides | 2022 |
A targeted extracellular vesicles loaded with montelukast in the treatment of demyelinating diseases.
Topics: Acetates; Animals; Cell Differentiation; Cell Lineage; Cuprizone; Cyclopropanes; Demyelinating Diseases; Disease Models, Animal; Drug Delivery Systems; Exosomes; Extracellular Vesicles; In Vitro Techniques; Ligands; Male; Mice; Mice, Inbred C57BL; Myelin Basic Protein; Myelin Sheath; Neurons; Oligodendrocyte Precursor Cells; Oligodendroglia; Phagocytosis; Quinolines; Receptor, Platelet-Derived Growth Factor alpha; Regeneration; Stem Cells; Sulfides | 2022 |
Cross-linked Alginate Beads of Montelukast Sodium Coated with Eudragit for Chronotherapy: Statistical Optimization,
Topics: Acetates; Alginates; Animals; Chitosan; Chronotherapy; Cyclopropanes; Delayed-Action Preparations; Glucuronic Acid; Hexuronic Acids; Male; Polymethacrylic Acids; Quinolines; Rabbits; Sulfides; Talc | 2022 |
Synthesis of Copper Oxide-Based Nanoformulations of Etoricoxib and Montelukast and Their Evaluation through Analgesic, Anti-Inflammatory, Anti-Pyretic, and Acute Toxicity Activities.
Topics: Acetates; Analgesics; Anti-Infective Agents; Anti-Inflammatory Agents; Chemistry Techniques, Synthetic; Copper; Cyclopropanes; Drug Compounding; Etoricoxib; Metal Nanoparticles; Quinolines; Spectrum Analysis; Structure-Activity Relationship; Sulfides | 2022 |
Neuropsychiatric Event on Withdrawal of Montelukast.
Topics: Acetates; Anti-Asthmatic Agents; Cyclopropanes; Humans; Leukotriene Antagonists; Quinolines; Sulfides | 2022 |
Montelukast ameliorated pemetrexed-induced cytotoxicity in hepatocytes by mitigating endoplasmic reticulum (ER) stress and nucleotide oligomerization domain-like receptor protein 3 (NLRP3) activation.
Topics: Acetates; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cyclopropanes; Endoplasmic Reticulum; Hepatocytes; Humans; Lung Neoplasms; NLR Family, Pyrin Domain-Containing 3 Protein; Nucleotides; Oxidative Stress; Pemetrexed; Quinolines; Reactive Oxygen Species; Sulfides | 2022 |
Identification of Montelukast as flavivirus NS2B-NS3 protease inhibitor by inverse virtual screening and experimental validation.
Topics: Acetates; Antiviral Agents; Cyclopropanes; Enzyme Inhibitors; Flavivirus; Humans; Peptide Hydrolases; Protease Inhibitors; Quinolines; Sulfides; Viral Nonstructural Proteins; Zika Virus; Zika Virus Infection | 2022 |
Neuropsychiatric reactions with the use of montelukast.
Topics: Acetates; Cyclopropanes; Humans; Quinolines; Sulfides | 2022 |
Montelukast, cysteinyl leukotriene receptor 1 antagonist, inhibits cardiac fibrosis by activating APJ.
Topics: Acetates; Animals; CHO Cells; Cricetinae; Cricetulus; Cyclopropanes; Fibrosis; Humans; Mice; Quinolines; Receptors, Leukotriene; Sulfides; Transforming Growth Factor beta | 2022 |
Montelukast, an Antagonist of Cysteinyl Leukotriene Signaling, Impairs Burn Wound Healing.
Topics: Acetates; Animals; Burns; Cyclopropanes; Endothelial Cells; Inflammation; Leukotrienes; Mice; Quinolines; Sulfides; Wound Healing | 2022 |
The safety of pranlukast and montelukast during the first trimester of pregnancy: A prospective, two-centered cohort study in Japan.
Topics: Abortion, Spontaneous; Acetates; Chromones; Cohort Studies; Cyclopropanes; Female; Humans; Infant, Newborn; Japan; Leukotriene Antagonists; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, First; Premature Birth; Prospective Studies; Quinolines; Sulfides | 2022 |
Leukotriene receptor antagonism with montelukast as a possible therapeutic for venous thromboembolism prophylaxis: An observational study.
Topics: Acetates; Cyclopropanes; Humans; Leukotriene Antagonists; Leukotrienes; Quinolines; Receptors, Leukotriene; Retrospective Studies; Sulfides; Venous Thromboembolism | 2022 |
Analysis of Neuropsychiatric Diagnoses After Montelukast Initiation.
Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Cohort Studies; Cyclopropanes; Female; Humans; Male; Mental Disorders; Middle Aged; Quinolines; Rhinitis, Allergic; Sulfides; Young Adult | 2022 |
Delayed Pressure Urticaria: Clinical and Diagnostic Features and Response to Omalizumab.
Topics: Acetates; Adrenal Cortex Hormones; Adult; Anti-Allergic Agents; C-Reactive Protein; Chronic Disease; Chronic Urticaria; Cyclopropanes; Cyclosporins; Female; Histamine Antagonists; Humans; Immunoglobulin E; Middle Aged; Omalizumab; Peroxidases; Quinolines; Sulfides; Treatment Outcome; Urticaria | 2022 |
Montelukast Inhibits HCoV-OC43 Infection as a Viral Inactivator.
Topics: Acetates; Animals; Coronavirus OC43, Human; COVID-19 Drug Treatment; Cyclopropanes; Middle East Respiratory Syndrome Coronavirus; Quinolines; SARS-CoV-2; Sulfides | 2022 |
Montelukast and Nightmares: Further Characterisation Using Data from VigiBase.
Topics: Acetates; Adverse Drug Reaction Reporting Systems; Child; Cyclopropanes; Dreams; Drug-Related Side Effects and Adverse Reactions; Humans; Quinolines; Sulfides | 2022 |
Structure-Based Virtual Screening Identifies Novobiocin, Montelukast, and Cinnarizine as TRPV1 Modulators with Anticonvulsant Activity
Topics: Acetates; Anticonvulsants; Cinnarizine; Cyclopropanes; Novobiocin; Quinolines; Sulfides; TRPV Cation Channels | 2022 |
Associations between sleep, obesity, and asthma in urban minority children.
Topics: Acetates; Adolescent; Adrenal Cortex Hormones; Anti-Allergic Agents; Asthma; Body Mass Index; Carbon Dioxide; Child; Cyclopropanes; Humans; Oxygen; Pediatric Obesity; Quinolines; Retrospective Studies; Sleep; Sulfides | 2022 |
The comparison between the effect of Glycyrrhizae uralensis (Gan-Cao) and Montelukast on the expression of T-bet and GATA-3 genes in children with allergic asthma.
Topics: Acetates; Asthma; Child; Cyclopropanes; Glycyrrhiza uralensis; Humans; Leukocytes, Mononuclear; Quinolines; Sulfides; T-Box Domain Proteins | 2022 |
The anti-inflammatory and antioxidant effects of Montelukast on lung sepsis in adult mice.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Antioxidants; Cyclopropanes; Disease Models, Animal; Hydroxyeicosatetraenoic Acids; Inflammation Mediators; Interleukin-17; Interleukin-6; Lung; Male; Mice; Quinolines; Sepsis; Sulfides | 2022 |
Preferential effect of Montelukast on Dapagliflozin: Modulation of IRS-1/AKT/GLUT4 and ER stress response elements improves insulin sensitivity in soleus muscle of a type-2 diabetic rat model.
Topics: Acetates; Animals; Antioxidants; Benzhydryl Compounds; Blood Glucose; Cyclopropanes; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endoplasmic Reticulum; Endoribonucleases; Glucose Transporter Type 4; Glucosides; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Leukotriene Antagonists; Metformin; Muscle, Skeletal; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Quinolines; Rats; Response Elements; Streptozocin; Sulfides | 2022 |
Oral montelukast reduces number and frequency of aphthous ulcers: a retrospective review.
Topics: Acetates; Cyclopropanes; Humans; Recurrence; Retrospective Studies; Stomatitis, Aphthous | 2023 |
Design of Montelukast Nanocrystalline Suspension for Parenteral Prolonged Delivery.
Topics: Acetates; Alzheimer Disease; Animals; Cyclopropanes; Nanoparticles; Particle Size; Quinolines; Rats; Solubility; Sulfides; Suspensions | 2022 |
Study on the Effect of Self-Made Lifei Dingchuan Decoction Combined with Western Medicine on Cough Variant Asthma.
Topics: Acetates; Asthma; Carbon Dioxide; Cough; Cyclopropanes; Fluticasone; Humans; Oxygen; Powders; Quinolines; Salmeterol Xinafoate; Sulfides; Tablets | 2022 |
Montelukast induces beneficial behavioral outcomes and reduces inflammation in male and female rats.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Antidepressive Agents; Cyclopropanes; Depression; Dimethyl Sulfoxide; Female; Humans; Inflammation; Inflammation Mediators; Interleukin-6; Male; Prostaglandins; Quinolines; Rats; Sucrose; Sulfides; Tumor Necrosis Factor-alpha | 2022 |
Multicenter Prospective Observational Study to Evaluate the Therapeutic Effect and Safety of a Combination of Montelukast and Levocetirizine for Allergic Rhinitis when Administered to Patients with Allergic Rhinitis and Asthma.
Topics: Acetates; Asthma; Cyclopropanes; Drug Combinations; Humans; Quality of Life; Quinolines; Rhinitis, Allergic; Treatment Outcome | 2022 |
The mechanisms underlying montelukast's neuropsychiatric effects - new insights from a combined metabolic and multiomics approach.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Glutathione; Hypothalamo-Hypophyseal System; Leukotriene Antagonists; Mice; Pituitary-Adrenal System; Quinolines | 2022 |
Montelukast reduces grey matter abnormalities and functional deficits in a mouse model of inflammation-induced encephalopathy of prematurity.
Topics: Acetates; Animals; Brain Diseases; Disease Models, Animal; Female; Gray Matter; Humans; Infant, Newborn; Inflammation; Male; Mice; Premature Birth; Quinolines | 2022 |
Enhanced efficacy of formoterol-montelukast salt in relieving asthma features and in preserving β2-agonists rescue therapy.
Topics: Acetates; Adrenergic beta-Agonists; Animals; Asthma; Formoterol Fumarate; Mice | 2022 |
Montelukast and risk for antidepressant treatment failure.
Topics: Acetates; Anti-Asthmatic Agents; Antidepressive Agents; Humans; Quinolines; Retrospective Studies; Treatment Failure; Treatment Outcome | 2023 |
Montelukast Inhibits Lung Cancer Cell Migration by Suppressing Cysteinyl Leukotriene Receptor 1 Expression
Topics: Acetates; Animals; Cell Movement; Humans; Leukotriene Antagonists; Lung Neoplasms; Mice | 2023 |
Protocol to study in vitro drug metabolism and identify montelukast metabolites from purified enzymes and primary cell cultures by mass spectrometry.
Topics: Acetates; Leukotriene Antagonists; Mass Spectrometry; Primary Cell Culture | 2023 |
β2-Adrenoreceptor Agonists, Montelukast, and Parkinson Disease Risk.
Topics: Acetates; Cyclopropanes; Humans; Parkinson Disease; Quinolines | 2023 |
Adverse drug reactions affecting treatment adherence in first-line treatment of asthma: An observational study.
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Child; Drug-Related Side Effects and Adverse Reactions; Humans; Leukotriene Antagonists; Male; Quinolines; Rhinitis, Allergic; Treatment Adherence and Compliance | 2023 |
Dose-response effect of Montelukast on post-extraction dental socket repair and skeletal phenotype of mice.
Topics: Acetates; Animals; Male; Mice; Tooth Extraction; Tooth Socket; Wound Healing | 2023 |
Psychiatric Adverse Effects of Montelukast-A Nationwide Cohort Study.
Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Cohort Studies; Drug-Related Side Effects and Adverse Reactions; Humans; Leukotriene Antagonists; Quinolines; Young Adult | 2023 |
Montelukast influence on kidney in experimental induced diabetes mellitus.
Topics: Acetates; Animals; Cyclopropanes; Diabetes Mellitus, Experimental; Kidney; Leukotriene Antagonists; Leukotrienes; Male; Quinolines; Rats; Rats, Wistar | 2023 |