Page last updated: 2024-08-23

phenyl acetate and leukotriene b4

phenyl acetate has been researched along with leukotriene b4 in 50 studies

Research

Studies (50)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (12.00)	18.7374
1990's	10 (20.00)	18.2507
2000's	24 (48.00)	29.6817
2010's	9 (18.00)	24.3611
2020's	1 (2.00)	2.80

Authors

Authors	Studies
Empey, LR; Fedorak, RN; Walker, K	1
Clandinin, MT; Empey, LR; Fedorak, RN; Garg, ML; Jewell, LD; Thomson, AB	1
Sabesin, SM; Sharon, P; Short, RM; Weidman, SW	1
O'Flaherty, JT; Tessner, TG; Wykle, RL	1
Chilton, FH; Cluzel, M; Undem, BJ	1
Arakawa, T; Fukuda, T; Kobayashi, K; Nakamura, H; Nebiki, H; Torii, Y	1
Berkenkopf, JW; Weichman, BM	1
Pickett, WC; Ramesha, CS	1
Prescott, SM; Seeger, AR; Zimmerman, GA	1
Eliakim, R; Karmeli, F; Okon, E; Rachmilewitz, D	2
Eliakim, R; Karmeli, F; Okon, E; Rachmilewitz, D; Samuni, A	1
Autore, G; Capasso, F; Di Carlo, G; Izzo, AA; Maiello, FM; Mascolo, N	1
Christman, BW; Kuratomi, Y; Lefferts, PL; Mueller, RA; Parker, RE; Smith, WG; Snapper, JR	1
Burch, RM; Lowe, VC; Muhlhauser, RO; Noronha-Blob, L	1
Chikazawa, Y; Furue, S; Hori, Y; Kuwabara, K; Maekawa, N; Matsukawa, A; Mikawa, K; Nishina, K; Obara, H; Ono, T; Shiga, M; Ueno, M; Yoshinaga, M	1
Mori, M; Okamura, S; Sakamoto, T; Saruya, SY; Yamashita, S	1
Haniuda, M; Izumi, T; Koyama, S; Kubo, K; Nagai, S; Nomura, H; Sato, E	1
Holma, R; Korpela, R; Riutta, A; Salmenperä, P; Vapaatalo, H; Virtanen, I	1
Laufer, S; Neupert, W; Tries, S	1
Lajeunesse, D; Laufer, S; Martel-Pelletier, J; Massicotte, F; Paredes, Y; Pelletier, JP	1
Barbanti, M; de Lima, OM; Distrutti, E; Fiorucci, S; Mencarelli, A; Morelli, A; Palazzini, E; Romano, M; Wallace, JL	1
Bonini, S; Bruscolini, A; Coassin, M; Lambiase, A; Rasi, G	1
Chilvers, ER; Dransfield, I; Haslett, C; Murray, J; O'Flaherty, JT; Rossi, AG; Ward, C	1
Cirino, G; Distrutti, E; Fiorucci, S; Laufor, SA; Mencarelli, A; Morelli, A; Wallace, JL	1
Fernandes, JC; Lajeunesse, D; Laufer, S; Martel-Pelletier, J; Pelletier, JP	1
Bezerra, MM; Cunha, Fde Q; da Rocha, FA; Girão, VC; Ribeiro, Rde A; Rocha, JC; Teixeira, MM	1
Caiaffa, MF; Haeggström, JZ; Macchia, L; Ramires, R; Tursi, A	1
Guévremont, M; Laufer, S; Marcouiller, P; Martel-Pelletier, J; Pelletier, JP; Ranger, P; Reboul, P	1
Alinovi, R; Baraldi, E; Carraro, S; Corradi, M; Pasquale, MF; Zacchello, F; Zanconato, S	1
Kulkarni, SK; Patil, CS; Singh, VP	1
Bristulf, J; Haeggström, JZ; Karlsson, U; Owman, C; Sabirsh, A	1
Caner, M; Cetinel, S; Gedik, N; Sakarcan, A; Sehirli, O; Sener, G; Velioğlu-Oğünç, A; Yeğen, BC	1
Cerletti, C; Dell'Elba, G; Evangelista, V; Manarini, S; Rotondo, S	1
Egido, J; Gómez-Gerique, JA; Gómez-Hernández, A; González, A; Ortega, L; Sánchez-Galán, E; Tuñón, J; Vidal, C	1
Leff, AR; Meliton, AY; Munoz, NM	1
Holma, R; Korpela, R; Salmenperä, P; Vapaatalo, H; Virtanen, I	1
Anderson, R; Feldman, C; Gravett, CM; Steel, HC; Theron, AJ; Tintinger, GR	1
Ayers, DC; Fanning, PJ; Gaur, T; Lian, JB; Mason-Savas, A; O'Connell, SL; Silva, J; Stein, GS; Wixted, JJ	1
Aquino, M; Bruno, I; Guerrero, MD; Payá, M; Riccio, R; Terencio, MC	1
Anderson, R; Cockeran, R; Feldman, C; Gravett, CM; Steel, HC; Theron, AJ; Tintinger, GR	1
Akyüz, C; Ercan, F; Ozkan, E; Sehirli, AO; Sener, G; Topaloğlu, U	1
Battu, GR; Chandra Shekar, KB; Parimi, R	1
Akakın, D; Çevik, Ö; Erşahin, M; Özbay, L; Şener, A; Şener, G; Yegen, BC	1
Barchuk, W; Barnathan, ES; Bertelsen, K; Fourie, A; Fuhr, R; Jiang, JZ; Lambert, J; Liu, X; Silkoff, PE; Thurmond, R	1
Li, J; Pan, JH	1
Abdel Kawy, HS	1
Bosland, MC; Said, MM	1
Haribabu, B	1
Alipour, S; Dastgheib, L; Fazelzadeh Haghighi, N; Ranjbar, S; Saki, N	1

Trials

4 trial(s) available for phenyl acetate and leukotriene b4

Article	Year
Montelukast, a leukotriene receptor antagonist, in vernal keratoconjunctivitis associated with asthma. Archives of ophthalmology (Chicago, Ill. : 1960), 2003, Volume: 121, Issue:5 Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Conjunctivitis, Allergic; Cyclopropanes; Enzyme-Linked Immunosorbent Assay; Female; Humans; Leukotriene Antagonists; Leukotriene B4; Leukotriene E4; Male; Ophthalmic Solutions; Peak Expiratory Flow Rate; Pilot Projects; Quinolines; Sulfides; Tears	2003
Effects of JNJ-40929837, a leukotriene A4 hydrolase inhibitor, in a bronchial allergen challenge model of asthma. Pulmonary pharmacology & therapeutics, 2014, Volume: 29, Issue:1 Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Bronchial Provocation Tests; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Epoxide Hydrolases; Female; Forced Expiratory Volume; Humans; Leukotriene B4; Male; Quinolines; Sputum; Sulfides; Thiazoles; Treatment Outcome; Tropanes; Young Adult	2014
[Clinical efficacy of montelukast for the treatment of bronchiolitis in infants]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2015, Volume: 17, Issue:10 Topics: Acetates; Bronchiolitis; Cyclopropanes; Humans; Infant; Leukotriene B4; Leukotriene E4; Quinolines; Sulfides	2015
Montelukast as an effective adjuvant in the treatment of moderate acne vulgaris. Dermatologic therapy, 2022, Volume: 35, Issue:10 Topics: Acetates; Acne Vulgaris; Anti-Bacterial Agents; Benzoyl Peroxide; Cyclopropanes; Dermatologic Agents; Double-Blind Method; Doxycycline; Gels; Humans; Immunoglobulin A; Leukotriene B4; Quinolines; Sulfides; Treatment Outcome	2022

Other Studies

46 other study(ies) available for phenyl acetate and leukotriene b4

Article	Year
Indomethacin worsens and a leukotriene biosynthesis inhibitor accelerates mucosal healing in rat colitis. Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:5 Topics: Acetates; Animals; Body Fluids; Colitis; Dialysis; Dinoprostone; Indoles; Indomethacin; Intestinal Mucosa; Leukotriene Antagonists; Leukotriene B4; Male; Misoprostol; Peroxidase; Rats; Rats, Sprague-Dawley	1992
Fish oil-enriched diet is mucosal protective against acetic acid-induced colitis in rats. Canadian journal of physiology and pharmacology, 1991, Volume: 69, Issue:4 Topics: Acetates; Acetic Acid; Animals; Body Fluids; Body Weight; Colon; Colonic Diseases, Functional; Dietary Fats; Dinoprostone; Eating; Fish Oils; Ileum; Intestinal Absorption; Intestinal Mucosa; Leukotriene B4; Male; Rats; Rats, Inbred Strains	1991
The effect of essential fatty acid deficiency on eicosanoid production in the inflamed rat colonic mucosa. Prostaglandins, leukotrienes, and essential fatty acids, 1990, Volume: 41, Issue:3 Topics: Acetates; Acetic Acid; Animals; Colitis; Eicosanoids; Fatty Acids, Essential; Female; In Vitro Techniques; Intestinal Mucosa; Leukotriene B4; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains	1990
Stimulation of platelet-activating factor synthesis by a nonmetabolizable bioactive analog of platelet-activating factor and influence of arachidonic acid metabolites. The Journal of biological chemistry, 1989, Mar-25, Volume: 264, Issue:9 Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetates; Arachidonic Acid; Arachidonic Acids; Calcimycin; Humans; Hydrolysis; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Neutrophils; Phospholipases A; Platelet Activating Factor	1989
Release of platelet-activating factor and the metabolism of leukotriene B4 by the human neutrophil when studied in a cell superfusion model. Journal of immunology (Baltimore, Md. : 1950), 1989, Dec-01, Volume: 143, Issue:11 Topics: Acetates; Calcimycin; Cell-Free System; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Leukotriene B4; Models, Biological; Neutrophils; Perfusion; Platelet Activating Factor; Suspensions; Tritium	1989
Roles of endogenous leukotrienes and prostaglandins in the healing of gastric ulcers induced by acetic acid in rats. Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 162 Topics: Acetates; Acetic Acid; Animals; Benzoquinones; Gastric Mucosa; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Prostaglandins; Quinones; Rats; Rats, Inbred Strains; Stomach Ulcer; Wound Healing	1989
Production of prostacyclin in mice following intraperitoneal injection of acetic acid, phenylbenzoquinone and zymosan: its role in the writhing response. Prostaglandins, 1988, Volume: 36, Issue:5 Topics: Acetates; Analgesics; Animals; Benzoquinones; Dinoprostone; Epoprostenol; Leukotriene B4; Male; Mice; Pain; Quinones; Radioimmunoassay; Reference Values; Zymosan	1988
Platelet-activating factor and leukotriene biosynthesis is inhibited in polymorphonuclear leukocytes depleted of arachidonic acid. The Journal of biological chemistry, 1986, Jun-15, Volume: 261, Issue:17 Topics: Acetates; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dietary Fats; Leukotriene B4; Neutrophils; Oligopeptides; Platelet Activating Factor; Rats	1986
Leukotriene B4 is an incomplete agonist for the activation of human neutrophils. Biochemical and biophysical research communications, 1984, Jul-31, Volume: 122, Issue:2 Topics: Acetates; Acetic Acid; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Aggregation; Chemotaxis, Leukocyte; Humans; Kinetics; Leukotriene B4; Neutrophils; Tritium	1984
Ketotifen ameliorates capsaicin-augmented acetic acid-induced colitis. Digestive diseases and sciences, 1995, Volume: 40, Issue:3 Topics: Acetates; Acetic Acid; Amino Acid Oxidoreductases; Animals; Capsaicin; Colitis; Colon; Intestinal Mucosa; Ketotifen; Leukotriene B4; Male; Mast Cells; NADPH Dehydrogenase; Neurons, Afferent; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley	1995
A stable nitroxide radical effectively decreases mucosal damage in experimental colitis. Gut, 1995, Volume: 37, Issue:3 Topics: Acetates; Animals; Antioxidants; Colitis; Cyclic N-Oxides; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Intestinal Mucosa; Leukotriene B4; Leukotriene C4; Lipoxygenase; Male; Peroxidase; Rats; Rats, Sprague-Dawley; Spin Labels; Time Factors; Trinitrobenzenesulfonic Acid	1995
Acetic acid-induced colitis in normal and essential fatty acid deficient rats. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:1 Topics: Acetates; Acetic Acid; Acid Phosphatase; Animals; Colitis; Dietary Fats; Dinoprostone; Fatty Acids; Leukotriene B4; Male; Platelet Activating Factor; Rats; Rats, Wistar	1995
Octreotide effectively decreases mucosal damage in experimental colitis. Gut, 1993, Volume: 34, Issue:2 Topics: Acetates; Acetic Acid; Animals; Colitis; Colon; Intestinal Mucosa; Leukotriene B4; Male; Octreotide; Platelet Activating Factor; Rats; SRS-A	1993
Effect of a 5-lipoxygenase inhibitor on endotoxin-induced pulmonary dysfunction in awake sheep. Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 74, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Acetates; Animals; Arachidonate 5-Lipoxygenase; Blood Pressure; Dinoprostone; Endotoxins; Female; Gas Chromatography-Mass Spectrometry; Granulocytes; Hemodynamics; Leukotriene B4; Lipoxygenase Inhibitors; Lung Diseases; Lymphatic System; Male; Phenols; Phenothiazines; Respiratory Mechanics; Sheep; Superoxides; Thromboxane B2	1993
NPC 15669, an inhibitor of neutrophil recruitment, is efficacious in acetic acid-induced colitis in rats. Gastroenterology, 1993, Volume: 104, Issue:4 Topics: Acetates; Acetic Acid; Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Colitis; Colon; Dexamethasone; Fluorenes; Glycine; Hydrocortisone; Leucine; Leukotriene B4; Male; Masoprocol; Mesalamine; Neutrophils; Peroxidase; Rats; Rats, Sprague-Dawley; Thromboxane B2	1993
Crucial role of group IIA phospholipase A(2) in oleic acid-induced acute lung injury in rabbits. American journal of respiratory and critical care medicine, 1999, Volume: 160, Issue:4 Topics: Acetates; Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extravascular Lung Water; Group II Phospholipases A2; Indoles; Interleukin-8; Keto Acids; Leukotriene B4; Lung; Lung Compliance; Male; Oleic Acid; Oxygen; Phospholipases A; Phospholipids; Pulmonary Edema; Rabbits; Respiratory Distress Syndrome; Thromboxane A2	1999
Activation of mucosal phospholipase D in a rat model of colitis. Journal of gastroenterology and hepatology, 2000, Volume: 15, Issue:10 Topics: Acetates; Acute Disease; Animals; Central Nervous System Depressants; Colitis; Colon; Data Interpretation, Statistical; Disease Models, Animal; Enzyme Activation; Ethanol; Female; Immunoenzyme Techniques; Intestinal Mucosa; Leukotriene B4; Luminescent Measurements; Peroxidase; Phospholipase D; Phospholipids; Rats; Rats, Wistar; Time Factors	2000
Histamine stimulates alveolar macrophages to release neutrophil and monocyte chemotactic activity. The Journal of laboratory and clinical medicine, 2001, Volume: 138, Issue:4 Topics: Acetates; Animals; Benzoquinones; Cattle; Cells, Cultured; Chemotactic Factors; Chromatography, Gel; Diethylcarbamazine; Histamine; Hot Temperature; Leukotriene B4; Macrophages, Alveolar; Masoprocol; Monocytes; Neutrophils; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serotonin; Trypsin	2001
Acute effects of the cys-leukotriene-1 receptor antagonist, montelukast, on experimental colitis in rats. European journal of pharmacology, 2001, Oct-19, Volume: 429, Issue:1-3 Topics: Acetates; Animals; Colitis; Cyclooxygenase 2; Cyclopropanes; Isoenzymes; Leukotriene Antagonists; Leukotriene B4; Male; Membrane Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Quinolines; Rats; Rats, Wistar; Receptors, Leukotriene; Severity of Illness Index; Sulfides	2001
The mechanism of action of the new antiinflammatory compound ML3000: inhibition of 5-LOX and COX-1/2. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2002, Volume: 51, Issue:3 Topics: Acetates; Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colon; Cyclooxygenase Inhibitors; Edema; Gastric Mucosa; Humans; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Male; Pyrroles; Rats; Rats, Sprague-Dawley; Rats, Wistar; Stomach; Thromboxane B2	2002
Study of the role of leukotriene B()4 in abnormal function of human subchondral osteoarthritis osteoblasts: effects of cyclooxygenase and/or 5-lipoxygenase inhibition. Arthritis and rheumatism, 2002, Volume: 46, Issue:7 Topics: Acetates; Alkaline Phosphatase; Blotting, Western; Cyclooxygenase Inhibitors; Dinoprostone; Female; Humans; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Male; Middle Aged; Nitrobenzenes; Osteoarthritis; Osteoblasts; Osteocalcin; Pyrroles; Quinolines; Sulfonamides	2002
Relative contribution of acetylated cyclo-oxygenase (COX)-2 and 5-lipooxygenase (LOX) in regulating gastric mucosal integrity and adaptation to aspirin. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:9 Topics: Acetates; Acetylation; Adaptation, Physiological; Animals; Arachidonate 5-Lipoxygenase; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Gastric Mucosa; Hydroxyeicosatetraenoic Acids; Isoenzymes; Leukotriene B4; Lipoxins; Lipoxygenase Inhibitors; Models, Biological; Prostaglandin-Endoperoxide Synthases; Pyrroles; Rats	2003
Role of leukotrienes in the regulation of human granulocyte behaviour: dissociation between agonist-induced activation and retardation of apoptosis. British journal of pharmacology, 2003, Volume: 139, Issue:2 Topics: Acetates; Adjuvants, Immunologic; Apoptosis; Benzopyrans; Calcium; Carboxylic Acids; Cell Survival; Cells, Cultured; Cyclopropanes; Eosinophils; Humans; Leukotriene Antagonists; Leukotriene B4; Leukotriene D4; Neutrophils; Quinolines; Sulfides	2003
Evidence that 5-lipoxygenase and acetylated cyclooxygenase 2-derived eicosanoids regulate leukocyte-endothelial adherence in response to aspirin. British journal of pharmacology, 2003, Volume: 139, Issue:7 Topics: Acetates; Acetylation; Adhesiveness; Arachidonate 5-Lipoxygenase; Aspirin; CD11a Antigen; Cells, Cultured; Cyclooxygenase 2; Dose-Response Relationship, Drug; E-Selectin; Eicosanoids; Endothelial Cells; Endothelium, Vascular; Fatty Alcohols; Glycols; Humans; Isoenzymes; Leukocytes; Leukotriene B4; Lipopolysaccharides; Lipoxins; Lipoxygenase; Membrane Proteins; Neutrophils; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Pyrans; Pyrroles; Quinolines; Quinolones; Umbilical Cord; Up-Regulation	2003
Treatment with licofelone prevents abnormal subchondral bone cell metabolism in experimental dog osteoarthritis. Annals of the rheumatic diseases, 2004, Volume: 63, Issue:1 Topics: Acetates; Animals; Antirheumatic Agents; Arthritis, Experimental; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Dogs; Enzyme Inhibitors; Insulin-Like Growth Factor I; Leukotriene B4; Lipoxygenase Inhibitors; Osteoarthritis; Osteoblasts; Pyrroles; Urokinase-Type Plasminogen Activator	2004
Blockade of leukotriene B4 prevents articular incapacitation in rat zymosan-induced arthritis. European journal of pharmacology, 2004, Aug-16, Volume: 497, Issue:1 Topics: Acetates; Animals; Arthritis, Experimental; Benzeneacetamides; Cell Movement; Cyclopropanes; Exudates and Transudates; Hindlimb; Hydroxamic Acids; Indoles; Joints; Leukotriene Antagonists; Leukotriene B4; Male; Quinolines; Rats; Rats, Wistar; Sulfides; Zymosan	2004
Novel inhibitory effect on 5-lipoxygenase activity by the anti-asthma drug montelukast. Biochemical and biophysical research communications, 2004, Nov-12, Volume: 324, Issue:2 Topics: Acetates; Allosteric Site; Animals; Anti-Asthmatic Agents; Asthma; Calcimycin; Calcium; Catalysis; Cell Line; Cell Line, Tumor; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclopropanes; Dexamethasone; Dose-Response Relationship, Drug; HL-60 Cells; Humans; Inhibitory Concentration 50; Kinetics; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Mast Cells; Neutrophils; Protein Binding; Quinolines; Rats; Recombinant Proteins; Sulfides	2004
Leukotriene and prostaglandin synthesis pathways in osteoarthritic synovial membranes: regulating factors for interleukin 1beta synthesis. The Journal of rheumatology, 2005, Volume: 32, Issue:4 Topics: Acetates; Aged; Arachidonic Acid; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; In Vitro Techniques; Leukotriene B4; Lipopolysaccharides; Male; Masoprocol; Naproxen; Osteoarthritis, Knee; Pyrroles; Signal Transduction; Synovial Membrane	2005
Exhaled breath condensate cysteinyl leukotrienes are increased in children with exercise-induced bronchoconstriction. The Journal of allergy and clinical immunology, 2005, Volume: 115, Issue:4 Topics: Acetates; Adolescent; Ammonia; Asthma, Exercise-Induced; Biomarkers; Breath Tests; Bronchoconstriction; Child; Cyclopropanes; Cysteine; Exhalation; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Leukotriene B4; Leukotrienes; Nitric Oxide; Quinolines; Respiratory Function Tests; Sulfides	2005
Effect of licofelone against NSAIDs-induced gastrointestinal ulceration and inflammation. Indian journal of experimental biology, 2005, Volume: 43, Issue:3 Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Female; Humans; Indomethacin; Inflammation; Leukotriene B4; Lipid Peroxidation; Male; Mesentery; Mice; Neutrophils; Pyrroles; Rats; Stomach Ulcer; Time Factors	2005
Non-specific effects of leukotriene synthesis inhibitors on HeLa cell physiology. Prostaglandins, leukotrienes, and essential fatty acids, 2005, Volume: 73, Issue:6 Topics: Acetates; Acrylates; Arachidonate 5-Lipoxygenase; Arachidonic Acids; Benzoates; Calcium Signaling; HeLa Cells; Humans; Indoles; Ionomycin; Leukocytes; Leukotriene Antagonists; Leukotriene B4; Organophosphonates; Polymerase Chain Reaction; Receptors, Leukotriene B4; Thapsigargin; Thiophenes; Transfection	2005
Montelukast protects against renal ischemia/reperfusion injury in rats. Pharmacological research, 2006, Volume: 54, Issue:1 Topics: Acetates; Animals; Blood Urea Nitrogen; Creatinine; Cyclopropanes; Glutathione; Interleukin-1; Interleukin-6; Kidney; L-Lactate Dehydrogenase; Leukotriene Antagonists; Leukotriene B4; Male; Malondialdehyde; Neutrophil Infiltration; Peroxidase; Quinolines; Rats; Rats, Wistar; Reperfusion Injury; Sulfides; Tumor Necrosis Factor-alpha	2006
The lipoxygenase-cyclooxygenase inhibitor licofelone prevents thromboxane A2-mediated cardiovascular derangement triggered by the inflammatory peptide fMLP in the rabbit. European journal of pharmacology, 2006, Sep-28, Volume: 546, Issue:1-3 Topics: Acetates; Animals; Aspirin; Blood Pressure; Cyclooxygenase Inhibitors; Disease Models, Animal; Electrocardiography; Heart Rate; Inflammation; Lactones; Leukotriene B4; Lipoxygenase Inhibitors; Male; Myocardial Ischemia; N-Formylmethionine Leucyl-Phenylalanine; Pyrroles; Rabbits; Sulfones; Thromboxane A2; Time Factors	2006
Licofelone, a balanced inhibitor of cyclooxygenase and 5-lipoxygenase, reduces inflammation in a rabbit model of atherosclerosis. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:1 Topics: Acetates; Animals; Atherosclerosis; Chemokine CCL2; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Leukotriene B4; Lipids; Lipoxygenase Inhibitors; Macrophages; Male; NF-kappa B; Pyrroles; Rabbits; RNA, Messenger; Thromboxane B2; Tunica Intima	2007
Blockade of avidity and focal clustering of beta 2-integrin by cysteinyl leukotriene antagonism attenuates eosinophil adhesion. The Journal of allergy and clinical immunology, 2007, Volume: 120, Issue:6 Topics: Acetates; Arachidonate 5-Lipoxygenase; Benzoquinones; CD11b Antigen; CD18 Antigens; Cell Adhesion; Cells, Cultured; Chemokine CCL11; Cyclopropanes; Cysteine; Eosinophils; Humans; Inflammation Mediators; Interleukin-5; Leukotriene Antagonists; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Quinolines; Sulfides	2007
Prophylactic potential of montelukast against mild colitis induced by dextran sulphate sodium in rats. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2007, Volume: 58, Issue:3 Topics: Acetates; Administration, Oral; Animals; Blotting, Western; Body Weight; Bridged Bicyclo Compounds; Colitis; Colon; Cyclooxygenase 1; Cyclooxygenase 2; Cyclopropanes; Dextran Sulfate; Dinoprostone; Immunochemistry; Immunoglobulin G; Leukotriene Antagonists; Leukotriene B4; Male; Nitric Oxide Synthase Type II; Occult Blood; Quinolines; Rats; Rats, Wistar; Severity of Illness Index; Sulfides; Thromboxane B2	2007
Montelukast inhibits neutrophil pro-inflammatory activity by a cyclic AMP-dependent mechanism. British journal of pharmacology, 2009, Volume: 156, Issue:1 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acetates; Calcium; Chemotactic Factors; Cyclic AMP; Cyclopropanes; Dose-Response Relationship, Drug; Fluorescent Dyes; Fura-2; Humans; In Vitro Techniques; Leukotriene Antagonists; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Pancreatic Elastase; Quinolines; Reactive Oxygen Species; Receptors, Leukotriene; Sulfides	2009
Enhanced fracture repair by leukotriene antagonism is characterized by increased chondrocyte proliferation and early bone formation: a novel role of the cysteinyl LT-1 receptor. Journal of cellular physiology, 2009, Volume: 221, Issue:1 Topics: Acetates; Animals; Arachidonate 5-Lipoxygenase; Cell Proliferation; Chondrocytes; Cyclopropanes; Fracture Healing; Fractures, Bone; Gene Expression Regulation; Hydroxyurea; Hypertrophy; Leukotriene Antagonists; Leukotriene B4; Mice; Models, Biological; Osteogenesis; Quinolines; Radiography; Receptors, Leukotriene; Sulfides	2009
Anti-inflammatory and analgesic activity of a novel inhibitor of microsomal prostaglandin E synthase-1 expression. European journal of pharmacology, 2009, Oct-12, Volume: 620, Issue:1-3 Topics: 4-Butyrolactone; Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Behavior, Animal; Blood Platelets; Cattle; Chronic Disease; Gene Expression Regulation, Enzymologic; Humans; Hyperalgesia; Inflammation; Intramolecular Oxidoreductases; Leukotriene B4; Male; Mice; Neutrophils; Prostaglandin-E Synthases; Thiophenes; Thromboxane B2	2009
Interactive inhibitory effects of formoterol and montelukast on activated human neutrophils. The European respiratory journal, 2010, Volume: 36, Issue:6 Topics: Acetates; Adrenergic beta-2 Receptor Agonists; Adult; Albuterol; Calcium Channels; CD18 Antigens; Cyclic AMP; Cyclopropanes; Cytochalasin B; Drug Interactions; Ethanolamines; Formoterol Fumarate; Humans; Leukotriene Antagonists; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Pancreatic Elastase; Quinolines; Rolipram; Sulfides; Superoxides	2010
Montelukast, a selective cysteinyl leukotriene receptor 1 antagonist, reduces cerulein-induced pancreatic injury in rats. Pancreas, 2010, Volume: 39, Issue:7 Topics: Acetates; Acute Disease; Animals; Ceruletide; Cyclopropanes; Cytokines; Female; Glutathione; Leukotriene Antagonists; Leukotriene B4; Lipid Peroxidation; Male; Pancreas; Pancreatitis; Peroxidase; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Leukotriene; Sodium-Potassium-Exchanging ATPase; Sulfides	2010
In vivo and in vitro pharmacological activity of Aristolochia tagala (syn: Aristolochia acuminata) root extracts. Pharmaceutical biology, 2011, Volume: 49, Issue:11 Topics: Acetates; Alkanes; Animals; Anti-Inflammatory Agents; Aristolochia; Calcimycin; Calcium Ionophores; Carrageenan; Cell Line; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Female; Inflammation; Interferon-gamma; Leukotriene B4; Macrophages; Male; Mice; Plant Extracts; Plant Roots; Plants, Medicinal; Rats; Rats, Wistar; Time Factors	2011
Montelukast inhibits caspase-3 activity and ameliorates oxidative damage in the spinal cord and urinary bladder of rats with spinal cord injury. Prostaglandins & other lipid mediators, 2012, Volume: 99, Issue:3-4 Topics: Acetates; Animals; Behavior, Animal; Caspase 3; Cyclopropanes; Down-Regulation; Glutathione; Interleukin-1beta; Leukotriene Antagonists; Leukotriene B4; Lipid Peroxidation; Luminescent Measurements; Luminol; Malondialdehyde; Neutrophil Infiltration; Neutrophils; Oxidative Stress; Peroxidase; Quinolines; Rats; Rats, Wistar; Spinal Cord; Spinal Cord Injuries; Sulfides; Tumor Necrosis Factor-alpha; Urinary Bladder	2012
Montelukast versus Dexamethasone Treatment in a Guinea Pig Model of Chronic Pulmonary Neutrophilic Inflammation. COPD, 2016, Volume: 13, Issue:4 Topics: Acetates; Animals; Bronchoalveolar Lavage Fluid; Chronic Disease; Cyclopropanes; Dexamethasone; Disease Models, Animal; Glucocorticoids; Guinea Pigs; Histone Deacetylases; Inflammation; Leukocyte Count; Leukotriene Antagonists; Leukotriene B4; Lipopolysaccharides; Lung; Male; Malondialdehyde; Neutrophils; Pulmonary Disease, Chronic Obstructive; Quinolines; Respiratory Hypersensitivity; Sulfides; Tumor Necrosis Factor-alpha	2016
The anti-inflammatory effect of montelukast, a cysteinyl leukotriene receptor-1 antagonist, against estradiol-induced nonbacterial inflammation in the rat prostate. Naunyn-Schmiedeberg's archives of pharmacology, 2017, Volume: 390, Issue:2 Topics: Acetates; Animals; Anti-Inflammatory Agents; Chemokine CCL2; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; E-Selectin; Estradiol; Gene Expression Regulation; Inflammation Mediators; Interleukin-6; Leukotriene Antagonists; Leukotriene B4; Male; NF-kappa B; Nitric Oxide Synthase Type II; Orchiectomy; Prostate; Prostatitis; Quinolines; Rats, Wistar; Receptors, Leukotriene; Sulfides; Time Factors; Tumor Necrosis Factor-alpha	2017
Back to the future of targeting leukotriene B Seminars in immunology, 2017, Volume: 33 Topics: 5-Lipoxygenase-Activating Proteins; Acetates; Animals; Asthma; Cell Movement; Chemokines; Cyclopropanes; Epoxide Hydrolases; Humans; Inflammation; Leukotriene B4; Lipid Metabolism; Molecular Targeted Therapy; Neutrophil Activation; Neutrophils; Quinolines; Sulfides; T-Lymphocytes	2017