phenyl acetate has been researched along with gamma-aminobutyric acid in 1213 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 110 (9.07) | 18.7374 |
| 1990's | 475 (39.16) | 18.2507 |
| 2000's | 606 (49.96) | 29.6817 |
| 2010's | 15 (1.24) | 24.3611 |
| 2020's | 7 (0.58) | 2.80 |
| Authors | Studies |
|---|---|
| Collins, RC; Mehta, S | 1 |
| Benton, D; Rick, JT | 1 |
| Takeuchi, H; Watanabe, K | 1 |
| Hansen, S; Perry, TL | 1 |
| Avanzini, G; Caraceni, T; Giovannini, P; Girotti, F | 1 |
| Ruchinskaia, TIu; Sverdlov, IuS | 1 |
| Beart, PM; Minchin, MC | 2 |
| Minchin, MC | 3 |
| Kashiki, Y; Mukherji, B; Ohyanagi, H; Sloviter, HA | 1 |
| Ho, PP; Walters, PC; Young, AL | 1 |
| Bradford, HF; Davison, AN; Harvey, PK | 1 |
| Butler, IJ; Enna, SJ; Ferkany, JW | 1 |
| Katz, RJ; Liebler, L | 1 |
| Löscher, W | 2 |
| Kurylo, E; Newstead, JD; Russell, MP; Wood, JD | 1 |
| Cheng, SC | 1 |
| Chase, TN; Pericić, D; Walters, JR | 1 |
| Avoli, M; Barra, PF; Brancati, A; Deodati, M; Vagnozzi, R | 1 |
| Frey, HH; Löscher, W | 1 |
| Pifferi, G; Pinza, M | 1 |
| Eng, N; Miller, LP; Pericić, D; Walters, JR | 1 |
| Eng, N; Pericić, D; Walters, JR | 1 |
| Kurylo, E; Newstead, JD; Wood, JD | 1 |
| Abe, M | 1 |
| Fonnum, F; Minchin, MC | 1 |
| Emson, PC | 1 |
| Curtis, DR; Lodge, D | 1 |
| Peesker, SJ; Wood, JD | 1 |
| Bloomfield, MR; Green, AR; Tordoff, AF | 1 |
| Kääriäinen, I | 1 |
| Lassánová, M; Nádvornik, P; Sramka, M; Turský, T | 1 |
| Starr, MS | 3 |
| Elazar, Z; Gottesfeld, Z | 1 |
| Balázs, R; Patel, AJ | 1 |
| Balázs, R; Johnson, AL; Möhler, H; Patel, AJ; Reynolds, AP | 1 |
| Henry, JL; Krnjevíc, K; Morris, ME | 1 |
| Dzubow, L; Garfinkel, D; London, JW; Nicklas, WJ | 1 |
| Matheson, DF; van den Berg, CJ | 1 |
| Starr, MS; Tanner, T | 1 |
| Boĭko, SS; Ostrovskaia, RU; Zuboskaia, AM | 1 |
| Abe, M; Murakami, K; Murakami, Y | 1 |
| Miranda, R; Orrego, F | 1 |
| Johnston, GA | 1 |
| Ben-Menachem, E; Hedner, T; Persson, LI | 1 |
| Chmelir, T; Ojemann, LM; Ricker, BA; Temkin, NR; Wallace, J; Wilensky, AJ | 1 |
| Fernández, A; Ruiz, RM; Serrano, I; Serrano, JS | 1 |
| Fonnum, F; Hassel, B; Johnsen, A; Paulsen, RE | 1 |
| Chaturvedi, PR; Lodhi, SA; Nesbitt, RU; Silbering, SB; Zour, E | 1 |
| Kaila, K; Mason, MJ; Mattsson, K; Pasternack, M; Voipio, J | 1 |
| Bleavins, MR; Bobrowski, WF; Dominick, MA; Gough, AW; Robertson, DG; Sigler, RE | 1 |
| Foot, M; Wallace, J | 1 |
| Chadwick, D | 3 |
| Fromm, GH; Kondo, T; Schmidt, B | 1 |
| Hönack, D; Löscher, W; Taylor, CP | 1 |
| Graves, NM; Leppik, IE | 2 |
| Bachelard, HS; Badar-Goffer, RS; Morris, PG | 1 |
| Cerdan, S; Künnecke, B; Seelig, J | 1 |
| Maurer, HH; Rump, AF | 1 |
| Eadie, MJ; Herkes, GK; Hooper, WD; Kavanagh, MC | 1 |
| Dickinson, RG; Hooper, WD; Kavanagh, MC | 1 |
| Kihara, M; Kubo, T | 1 |
| Porter, RJ | 1 |
| Peeling, J; Sutherland, GR; Wong, D | 1 |
| Machen, VL; Swaiman, KF | 1 |
| Gramer, M; Hönack, D; Löscher, W | 1 |
| Bossu, JL; Théorĕt, Y | 1 |
| Sun, Y; Wang, XG; Zhu, JQ | 1 |
| Dichter, MA; Snodgrass, SR; White, WF | 1 |
| Burchfiel, JL; Duffy, FH; Joy, RM; Mower, GD; Snodgrass, SR | 1 |
| Clarenbach, P; Krätzschmar, S; Rao, ML; Vahlensieck, M | 1 |
| Kontro, P; Oja, SS | 1 |
| Beshears, JF; Commissaris, RL; Halas, NA; McCloskey, TC | 1 |
| Blumhardt, L; Chadwick, D; Crawford, P; Ghadiali, E; Lane, R | 1 |
| Grünberger, J; Linzmayer, L; Saletu, B | 1 |
| Bugera-Piecuch, TE; Kittel, M; Kosicka, B; Smiałek, M | 1 |
| Borsini, F; Evangelista, S; Meli, A | 1 |
| Kölle, EU; Vollmer, KO; von Hodenberg, A | 1 |
| Alpern, HP; McIntyre, TD | 1 |
| Bedwani, JR; Horne, AL | 1 |
| Löscher, W; Vetter, M | 2 |
| Hengy, H; Kölle, EU | 1 |
| Göthert, M; Reimann, W; Schlicker, E | 1 |
| Hansen, S; Kennedy, J; Perry, TL; Urquhart, N | 1 |
| Iversen, LL; Minchin, MC | 1 |
| Constanti, A; Quilliam, JP | 1 |
| Roberts, E; Wu, JY | 1 |
| Kennedy, AJ; Marshall, J; Voaden, MJ | 1 |
| Anderson, EG; Bell, JA | 1 |
| Benoit-Guyod, JL; Cohen-Addad, C; Eymard, P; Ferrandes, B | 1 |
| Crossman, AR; Walker, RJ; Woodruff, GN | 1 |
| Haefely, W; Möhler, H; Polc, P | 1 |
| Mikhailov, GA; Osadchaia, LM; Prokhorova, MI; Zakharova, LI | 1 |
| Roberts, E; Schousboe, A; Wu, JY | 1 |
| Drummond, RJ; Phillips, AT | 1 |
| Berl, S; Krespan, B; Nicklas, WJ | 1 |
| Cortesini, C; Lombardi, G; Moneti, G; Moroni, F | 1 |
| Babu, GN; Vijayan, E | 1 |
| Hunt, WA; Wixon, HN | 1 |
| Antonaccio, MJ; Taylor, DG; Taylor, KA | 1 |
| Gomes, C; Leite, JR; Pagliusi, SR; Trolin, G | 1 |
| Lassánová, M; Turský, T | 1 |
| Bedwani, JR; Songra, AK; Trueman, CJ | 1 |
| Davison, AJ | 1 |
| Reimann, W | 1 |
| Kurylo, E; Tsui, SK; Wood, JD | 1 |
| Bolin, P; Da Vanzo, JP | 1 |
| López, MS; Martin de Rio, R | 1 |
| Bernasconi, R; Maitre, L; Martin, P; Raschdorf, F | 1 |
| Gomes, C; Trolin, G | 1 |
| Debeljuk, L; Díaz, MC; Goijman, S; Rettori, VB; Seilicovich, A | 1 |
| Asakura, T; Mizuno, A | 1 |
| Hosogi, H; Kageyama, J; Ofuji, T; Takahara, J; Yakushiji, W; Yunoki, S | 1 |
| Le Gal La Salle, G | 1 |
| Smiałowska, M | 1 |
| Carmona, E; Gomes, C; Trolin, G | 2 |
| Kurylo, E; Russell, MP; Wood, JD | 1 |
| Despland, PA | 2 |
| Gil, KB; Kang, H; Moshé, SL; Shinnar, S; Wolf, SM | 1 |
| Kelly, KM; Macdonald, RL; Rock, DM | 1 |
| Kelly, KM; Macdonald, RL | 3 |
| Taylor, CP | 4 |
| Garcia, LL; Oles, K; Shihabi, ZK | 1 |
| Bockbrader, HN; Chang, T; DeHart, PD; Hanson, BJ; McNally, WP; Radulovic, LL; Türck, D; Vollmer, KO; von Hodenberg, A | 1 |
| Mellick, GA; Mellick, LB; Mellicy, LB | 1 |
| Kilpatrick, C | 1 |
| Kupecz, D | 1 |
| Cooke, L; Short, C | 1 |
| Gidal, BE; Kempf, T; Lensmeyer, GL; Wiebe, DA | 1 |
| Tietz, EI; Xie, XH; Zeng, X | 1 |
| Ryback, L; Ryback, R | 1 |
| Bockbrader, HN; Eldon, MA; Halstenson, CE; Keane, WF; Sedman, AJ; Türck, D; Underwood, BA; Wong, MO | 1 |
| Goa, KL; Sorkin, EM | 1 |
| Campbell, G; Lunney, E; Oxender, DL; Su, TZ | 1 |
| Murdoch, LA | 1 |
| de la Iglesia, FA; Gough, AW; Sigler, RE | 2 |
| Pimentel, J; Pinto, F | 1 |
| Tatum, WO; Zachariah, SB | 1 |
| Betts, T | 1 |
| Bloom, DS; O'Neill, BA; Trimble, MR | 1 |
| Brodie, MJ; Leach, JP | 1 |
| Honmou, O; Kocsis, JD; Richerson, GB | 1 |
| Devinsky, O; Luciano, D; Vazquez, B | 1 |
| Calvo, R; Cerdán, S; Chapa, F; Escobar del Rey, F; Künnecke, B; Morreale de Escobar, G | 1 |
| Mellick, GA; Mellick, LB | 3 |
| Andrews, CO; Fischer, JH | 1 |
| Beran, RG | 1 |
| Anderson, JA; Petrere, JA | 1 |
| de la Iglesia, FA; Fowler, ML; Lalwani, ND; Reddy, JK; Sigler, RE | 1 |
| Upton, N | 1 |
| Campbell, M; Krauss, GL; Simmons-O'Brien, E | 1 |
| Tyndel, F | 1 |
| Patsalos, PN; Sander, JW | 1 |
| Kälviäinen, R; Riekkinen, PJ; Sivenius, J; Ylinen, A | 1 |
| Buchanan, N | 1 |
| Laxer, KD | 1 |
| Patsalos, PN | 2 |
| McLean, MJ | 3 |
| Ramsay, RE | 2 |
| Leiderman, DB | 1 |
| Fromm, GH | 1 |
| Honmou, O; Kocsis, JD | 1 |
| Blum, RA; Bockbrader, H; Busch, JA; Comstock, TJ; Keller, E; Reece, PA; Reetze, P; Schultz, RW; Sica, DA; Tuerck, D | 1 |
| Dostrow, VG; Noble, SL; Parks, BR | 1 |
| Petersen, SB; Schousboe, A; Sonnewald, U; Svendsen, JS; Unsgård, G; Westergaard, N | 1 |
| Bachelard, HS; Badar-Goffer, RS; Ben-Yoseph, O; Morris, PG | 1 |
| Byers, VL | 1 |
| Schielke, GP; Taylor, CP; Vartanian, MG; Welty, DF | 1 |
| Leppik, IE | 1 |
| McLean, MJ; Wamil, AW | 1 |
| Harden, CL | 2 |
| Barr, AN; Fischer, JH; Fischer, PA; Rogers, SL; Trudeau, VL | 1 |
| Manack, L; Skolnick, AA | 1 |
| Ramsay, RE; Slater, JD | 1 |
| Okamoto, Y; Ota, K | 1 |
| Brown, JP; Gee, NS; Hill, DR; Thurlow, RJ; Woodruff, GN | 1 |
| Bigge, C; Hill, DR; Suman-Chauhan, N; Taylor, CP; Vartanian, MG; Yuen, PW | 1 |
| Hill, DR; Suman-Chauhan, N; Webdale, L; Woodruff, GN | 1 |
| Hill, DR; Suman-Chauhan, N; Woodruff, GN | 1 |
| Feuerstein, TJ; Götz, E; Lais, A; Meyer, DK | 1 |
| Bockbrader, HN; Kugler, AR; Stewart, BH; Thompson, PR | 1 |
| Bialer, M | 1 |
| Aguilera, L; Fauré, E; Galdames, D | 1 |
| Lee, EK | 1 |
| Ben-Menachem, E; Hamberger, A; Hedner, T; Persson, LI; Söderfelt, B | 1 |
| Honmou, O; Kocsis, JD; Oyelese, AA | 1 |
| Kochen, S | 1 |
| Goldlust, A; Oxender, DL; Su, TZ; Taylor, CP; Welty, DF | 1 |
| Behar, KL; Lamoureux, D; Mattson, RH; Petroff, OA; Rothman, DL | 1 |
| Cory, PR; Gidal, Be | 1 |
| Rothstein, JD; Schielke, GP; Welty, DF | 1 |
| Vassella, F | 1 |
| Krämer, G | 1 |
| Shokry, A | 1 |
| Despland, PA; Krämer, G; Vassella, F; Wieser, HG | 1 |
| Crozier, S; Doddrell, DM; Glen, S; Hockings, PD; Hunter, AJ; Middleton, DA; Reid, DG; Roffman, W; Rose, SE; Rothaul, AL | 1 |
| Cesena, M; Helmers, SL; Lee, DO; Mikati, MA; Riviello, JJ; Steingard, RJ | 1 |
| Cochran, JW; Williams, LB | 1 |
| Lo, W; Nahata, MC; Tallian, KB; Tsao, CY | 1 |
| Buetefisch, CM; Gutierrez, A; Gutmann, L | 1 |
| Vossler, DG | 1 |
| Brown, JP; Dissanayake, VU; Gee, NS; Offord, J; Thurlow, R; Woodruff, GN | 1 |
| Reynolds, NC | 1 |
| French, JA | 1 |
| Perucca, E | 2 |
| Zapp, JJ | 2 |
| Pellock, JM | 3 |
| Anderson, J; Helmers, S; Holmes, G; Khurana, DS; Mikati, MA; Riviello, J | 1 |
| Legido, A | 1 |
| Kanthasamy, AG; Truong, DD; Vu, TQ; Yun, RJ | 1 |
| Beydoun, A; Sackellares, JC; Uthman, BM | 1 |
| Gaily, E; Iivanainen, M | 1 |
| Loiseau, P | 1 |
| Wang, Y; Welty, DF | 1 |
| Fernández, MC; Petersen, LR; Walkotte, SM; Walter, FG | 1 |
| Davies, JA | 1 |
| Kestenbaum, A; Rosner, H; Rubin, L | 1 |
| Perry, JR; Sawka, C | 1 |
| Romano, JG | 1 |
| Hill, DR; Thurlow, RJ; Woodruff, GN | 2 |
| Dimond, KR; Lamoreaux, L; Pande, AC; Pierce, MW | 1 |
| Naritoku, DK; Patel, J | 1 |
| Rordorf, G; Segal, AZ | 1 |
| Binnie, CD; Elwes, RD | 1 |
| Cockerell, OC; Hughes, D | 1 |
| McDonnell, GV; Morrow, JI | 1 |
| Lönnecker, S; Paulus, W; Steinhoff, BJ; Ziemann, U | 1 |
| Bourgeois, BF | 4 |
| Brodie, MJ; Forrest, G; Leach, JP; Sills, GJ | 1 |
| Haider, A; Haider, S; Tuchek, JM | 1 |
| Krahn, LE; Reeves, AL; Sharbrough, FW; So, EL | 1 |
| Bhaumik, S; Hauck, A | 1 |
| Gidal, BE; Haley, K; Maly, MM; Nemire, RE | 1 |
| Hussein, G; Montouris, G; Troupin, AS | 1 |
| Butterworth, RF; Sonnewald, U; Therrien, G | 1 |
| Cerdán, S; Preece, NE | 1 |
| Lee, BI | 1 |
| Ferris, P; Field, MJ; Hunter, JC; Oles, RJ; Singh, L; Williams, RG; Woodruff, GN | 1 |
| Morton, LD; Pellock, JM | 1 |
| Poklis, A; Saady, JJ; Wolf, CE | 1 |
| Cook, LL; Persinger, MA | 1 |
| Duthie, T; Jackson, D | 1 |
| Williams, DC | 1 |
| Chadwick, DW; Kadir, ZA; Marson, AG | 1 |
| Budde, J; Gidal, BE; Jones, JC; Lensmeyer, GL; Maly, MM; Pitterle, ME | 1 |
| Meldrum, BS | 1 |
| Gram, L | 1 |
| Chadwick, DW; Kadir, Z; Marson, T | 1 |
| Mattson, RH | 1 |
| Brady, LA; Do, SM; Fernandez, MC; Kloster, JC; Prosnitz, EH; Ruffenach, SJ; Salmon, JV; Villarin, A; Walter, FG | 1 |
| Bruni, J | 3 |
| Alexander, J; Chadwick, D; Garofalo, E; Leiderman, DB; Sauermann, W | 1 |
| Armon, C; Barohn, RJ; Bromberg, MB; Bryan, WW; Gelinas, DF; Mendoza, MC; Miller, RG; Moore, D; Neville, HE; Parry, GJ; Petajan, JH; Ravits, JM; Ringel, SP; Ross, MA; Young, LA | 1 |
| Andrus, PK; Cutting, FB; Doble, A; Gurney, ME; Hall, ED; Taylor, CP; Zhai, P | 1 |
| Herranz, JL | 2 |
| Grippo, J | 1 |
| Appleton, RE | 1 |
| Bloms-Funke, P; Löscher, W | 1 |
| Gordon, SM; Regan, WM | 1 |
| Keck, PE; McElroy, SL; Stanton, SP | 1 |
| Schaffer, CB; Schaffer, LC | 2 |
| Fleisher, D; Kim, J; Stevenson, CM | 1 |
| Nissani, M; Sanchez, EA | 1 |
| Morris, HH | 2 |
| Brodie, MJ; Wilson, EA | 1 |
| Graves, DE; Mueller, M; Olson, WH; Priebe, MM; Sherwood, AM | 1 |
| Johannessen, SI | 1 |
| Shorvon, S; Stefan, H | 1 |
| Bannister, SM; Morton, LD; Pellock, JM | 1 |
| Adler, CH | 1 |
| Kosek, P; McGraw, T | 1 |
| Dickenson, AH; Singh, L; Stanfa, LC; Williams, RG | 1 |
| Hosford, DA; Wang, Y | 1 |
| Anhut, H; Ebersole, J; Garofalo, E; LaMoreaux, L; Myers, S; Trudeau, V | 1 |
| Brodie, MJ; Girvan, J; Leach, JP; Paul, A | 1 |
| Davis, AM; Elliott, KJ; Inturrisi, CE; Shimoyama, M; Shimoyama, N | 1 |
| Brown, JP; Dissanayake, VU; Gee, NS; Woodruff, GN | 1 |
| Brodsky, L; Munasifi, F; Ryback, RS | 1 |
| Fontana, DJ; Gogas, KR; Hedley, LR; Hunter, JC; Jacobson, LO; Kassotakis, L; Thompson, J | 1 |
| Arbizu, T; Padró, L; Rovira, R | 1 |
| Filadora, V; Lema, M; Miner, M; Sist, T | 1 |
| Bergen, D; Blesi, K; Gapany, S; Gil-Nagel, A; Villanueva, N | 1 |
| Bhaumik, S; Branford, D; Duggirala, C; Ismail, IA | 1 |
| Chapman, DP; Giles, WH | 1 |
| Gruenthal, M; Mueller, ME; Olson, WH; Olson, WL | 2 |
| Averbuch-Heller, L; Büttner, U; Fuhry, L; Ganser, GL; Heide, W; Leigh, RJ; Rottach, KG; Tusa, RJ | 1 |
| Childers, MK; Holland, D | 1 |
| Daras, M; Koppel, BS; Samkoff, LM; Tuchman, AJ | 1 |
| Chudnow, RS; Dewey, RB; Lawson, CR | 1 |
| Brodie, MJ; Butler, E; Forrest, G; Leach, JP; Sills, GJ; Thompson, GG | 1 |
| Stringer, JL; Xiong, ZQ | 1 |
| Vossler, DG; Wyler, AR | 1 |
| Keck, PE; Kmetz, GF; McElroy, SL; Soutullo, CA | 1 |
| Barrientos, N; Chaná, P; de Marinis, A | 1 |
| Dalby, NO; Nielsen, EB | 1 |
| DeCerce, J; DeToledo, JC; Ramsay, RE; Toledo, C | 1 |
| Bockbrader, HN; Fleisher, D; Radulovic, LL; Stevenson, CM | 1 |
| Field, MJ; Hughes, J; Lewis, AS; McCleary, S; Oles, RJ; Singh, L | 1 |
| Connelly, JF; Wetzel, CH | 1 |
| de Rosayro, AM; Harrell, C; Ristic, H; Rosenberg, JM; Werner, RA | 1 |
| Bergey, GK; Blume, WT; Crockatt, JG; Garofalo, E; LaMoreaux, L; Leiderman, DB; Morrell, MJ; Morris, HH; Penovich, PE; Pierce, M; Rosenfeld, W | 1 |
| Abou-Khalil, B; Beydoun, A; Cantrell, D; Fischer, J; Garofalo, E; Greiner, M; Harden, C; Hayes, A; Labar, DR; Pierce, M; Ramsay, RE; Sackellares, JC; Uthman, BM | 1 |
| Barron, TF; Hunt, SL | 1 |
| Elliott, KJ; Inturrisi, CE; Shimoyama, M; Shimoyama, N | 1 |
| Carson, WH; Finkenbine, R; King, L; Markowitz, JS; Myrick, H | 1 |
| Field, MJ; Holloman, EF; Hughes, J; McCleary, S; Singh, L | 1 |
| Holmes, GL | 1 |
| Autret, E; Billard, C; Jonville-Bera, AP; Picard, C | 1 |
| Joffe, RT; MacDonald, C; Patelis-Siotis, I; Robb, JC; Young, LT | 1 |
| Gruenthal, M; Mueller, M; Olson, WH; Olson, WL; Priebe, MM; Sherwood, AM | 1 |
| Chudnow, RS; Mimbela, RA; Owen, DB; Roach, ES | 1 |
| Khatri, A; Pearlstein, L | 1 |
| Houtchens, MK; Richert, JR; Rose, JW; Sami, A | 1 |
| Pierce, MW; Shokry, A | 1 |
| Franm, L; Lucier, E | 1 |
| Del Bianco, PL; Nicolodi, M; Sicuteri, F | 1 |
| Little, HJ; Robinson, E; Watson, WP | 1 |
| Gillin, S; Sorkin, LS | 1 |
| Freeman, MP; Stoll, AL | 1 |
| Chaplan, SR; Partridge, BJ; Sakamoto, E; Yaksh, TL | 1 |
| Briggs, AR; Brown, JP; Dissanayake, VU; Gee, NS; Milic, MR | 1 |
| Jun, JH; Yaksh, TL | 1 |
| Newshan, G | 1 |
| Stopforth, J | 1 |
| Curry, WJ; Kulling, DL | 1 |
| Brodie, MJ; Forrest, G; Sills, GJ; Wilson, EA | 1 |
| Bailey, CP; Little, HJ; Molleman, A | 1 |
| Krämer, G; Wad, N | 1 |
| Bazil, CW; Pedley, TA | 1 |
| Gould, HJ | 1 |
| Bittermann, HJ; Herrendorf, G; Kurth, C; Steinhoff, BJ | 1 |
| Corá-Locatelli, G; Greenberg, BD; Martin, JD; Murphy, DL | 1 |
| Johannessen, SI; Nakken, KO; Rytter, E | 2 |
| Arzimanoglou, A; Baulac, M; Cavalcanti, D; Portal, JJ; Semah, F | 1 |
| Boden, P; Brown, JP; Dooley, DJ; Gee, NS; Kocsis, JD; Singh, L; Su, TZ; Taylor, CP; Welty, DF | 1 |
| Petroff, OA; Rothman, DL | 1 |
| McCaffery, M | 1 |
| Boothe, DM | 1 |
| Beauclair, L; Bélanger, MC; Chouinard, G | 1 |
| Cook, DE; Gidal, BE; Kowalski, JW; Maly, MM; Pitterle, ME; Rutecki, PA | 1 |
| Eldon, MA; Randinitis, EJ; Sedman, AJ; Underwood, BA | 1 |
| Carrazana, EJ; Schachter, SC | 1 |
| Abou-Khalil, B; Beydoun, A; Fakhoury, T; Nasreddine, W | 1 |
| Beck, H; Elger, CE; Schramm, J; Schumacher, TB; Steinhäuser, C | 1 |
| Chadwick, DW; Hutton, JL; Kadir, ZA; Marson, AG | 3 |
| Haugvicová, R; Mares, P | 1 |
| Birnbaum, AK; Caruso, KJ; Cloyd, JC; Jones Saete, C; Kriel, RL; Ricker, BJ | 1 |
| Baraldo, M; Benetello, P; Fortunato, M; Furlanut, M; Pea, F; Testa, G; Tognon, A | 1 |
| Chamarette, HL; Chapman, V; Dickenson, AH; Rygh, LJ; Suzuki, R | 1 |
| Miller, RG | 2 |
| Luer, MS; Winkler, SR | 1 |
| Bauer, J; Elger, CE; Scherrmann, J; Widman, G | 1 |
| Carceller, F; Cerdán, S; Pascual, JM; Roda, JM | 1 |
| Ancill, RJ; Holliday, SG; Sheldon, LJ | 1 |
| Cho, EH; Cho, SW; Choi, SY | 1 |
| Bryans, JS; Davies, N; Dissanayake, VU; Gee, NS; Horwell, DC; Kneen, CO; Morrell, AI; O'Neill, JA; O'Toole, JC; Oles, RJ; Perkins, GM; Ratcliffe, GS; Singh, L; Suman-Chauhan, N | 1 |
| Privitera, M; Shukla, R; Welty, TE | 1 |
| Anderson, GD | 1 |
| Busenbark, K; Hubble, JP; Koller, WC; Lyons, K; Pahwa, A; Pahwa, R; Rienerth, JD | 1 |
| Knoll, J; Stegman, K; Suppes, T | 1 |
| Dooley, DJ; Pugsley, TA; Whetzel, SZ | 1 |
| García-Albea, E | 1 |
| Casuto, LS; Keck, PE; Soutullo, CA | 1 |
| Köhling, R; Lücke, A; Mayer, T; Musshoff, U; Osterfeld, M; Schütte, W; Speckmann, EJ; Wolf, P | 1 |
| Matthews, J; Pollack, MH; Scott, EL | 1 |
| De Sarro, A; De Sarro, G; Gallelli, L; Gareri, P; Spagnolo, C | 1 |
| Evans, DL; Murphy, TK; Tueth, MJ | 1 |
| Keck, PE; McElroy, SL; Strakowski, SM | 1 |
| Nicolodi, M; Sicuteri, F | 1 |
| Bernardi, G; Spadoni, F; Stefani, A | 1 |
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| Berlowitz, D; Charbonneau, A; Cramer, J; Kazis, L; Knoefel, J; Mandell, A; Pugh, MJ | 1 |
| Athanasopoulos, A; Barbalias, G; Papathanasopoulos, P; Perimenis, P | 1 |
| Grady, MM; Stahl, SM | 1 |
| Honda, M; Oka, J; Ono, H; Shimizu, S; Tanabe, M | 1 |
| Feeney, L; Jacobs, B; McKeever, C; Reynolds, ER; Rojahn, E; Stauffer, EA | 1 |
| Bennett, MI; Simpson, KH | 1 |
| Dahl, JB; Dierking, G; Duedahl, TH; Fomsgaard, JS; Møiniche, S; Rasmussen, ML; Rømsing, J | 1 |
| Barton, D; Loprinzi, CL | 1 |
| Enna, SJ | 1 |
| Ahmadi, S; Bayer, K; Zeilhofer, HU | 1 |
| Griggs, JJ; Guttuso, TJ; Morrow, GR; Pandya, KJ; Roscoe, JA; Rosenblatt, JD; Sahasrabudhe, DM; Thummala, AR | 1 |
| Antonello, RM; Bava, A; Cazzato, G; Moretti, R; Torre, P; Ukmar, M | 1 |
| Petroianu, GA | 1 |
| Gau, CS; Lin, CJ; Liou, HH; Shyu, MK; Wu, SP | 1 |
| Carlsson, KC; Reubsaet, JL | 1 |
| Andersson, KE | 1 |
| Alvarez-Cermeño, JC; Herrero, A; Mariscal, A; Martinez-Castrillo, JC; Mera, J | 1 |
| Kundurović, Z; Rustembegovic, A; Sofic, E; Tahirović, I | 1 |
| Hogan, Q; Kanai, A; McCallum, JB; Sarantopoulos, C | 1 |
| Collins, ED; Foltin, RW; Haney, M; Hart, CL; Ward, AS | 1 |
| Guttuso, T | 1 |
| Kuraishi, Y; Nojima, H; Shiraki, K; Takahata, H; Takasaki, I | 1 |
| Aiyar, J; Bezverkov, RE; Boueres, JK; Chaudhary, A; Lim, J; Munoz, B; Orr, K; Pracitto, R; Santini, AM; Schaffhauser, H; Stock, N; Venkatraman, S | 1 |
| Nicholson, BD | 1 |
| Baron, R | 1 |
| Pandey, CK; Priye, S; Singh, PK; Singh, RB; Singh, S; Singh, U | 1 |
| Galask, RP; Lotery, HE; McClure, N | 1 |
| Hunt, DL; Khan, RB; Thompson, SJ | 1 |
| Alkhalil, B; Alkhalil, C; Hahar, N; Lowenthal, DT; Zavros, G | 1 |
| Camacho, A; González De La Aleja, J; Martínez-Salio, A; Penas, M; Porta-Etessam, J; Villarejo, A | 1 |
| Hamamcioglu, MK; Karamanlioğlu, B; Kurt, I; Memiş, D; Pamukçu, Z; Tükenmez, B; Turan, A | 1 |
| Levendoglu, F; Ogün, CO; Ogün, TC; Ozerbil, O; Ugurlu, H | 1 |
| Castellano, M; Cervera, G; Martínez-Raga, J; Perez-Galvez, B; Sabater, A | 1 |
| Bottomley, WW; Coulson, IH; Winhoven, SM | 1 |
| Abou-Khalil, B; Bautista, J; Bazil, C; Bergen, D; Beydoun, A; Bourgeois, B; Browne, T; Faught, RE; Fischer, JH; French, JA; Gidal, B; Glauser, TA; Harden, CL; Hirtz, D; Kanner, AM; Marks, WJ; Montouris, GD; Nespeca, M; Sachdeo, RC; Schachter, SC; Stern, J; Theodore, WH; Turk, WR; Wilner, A | 4 |
| Aydinli, I; Keskinbora, K; Pekel, AF | 1 |
| Karamanlioğlu, B; Memiş, D; Pamukçu, Z; Turan, A; Türe, M; Usar, P | 1 |
| Choi, JI; Kwak, SH; Yoon, MH | 1 |
| Feuerstein, TJ; Knörle, R; Schulze-Bonhage, A | 1 |
| Lawrence, HJ; Nguyen, VH | 1 |
| Stahl, SM | 3 |
| Freye, E; Levy, JV; Partecke, L | 1 |
| Marshall, L | 1 |
| Başoğlu, M; Gürgör, N; Yetimalar, Y | 1 |
| Lenzer, J | 1 |
| Almahrezi, A; Fitzcharles, MA | 1 |
| Simpson, MA | 1 |
| Burdon, M; Deokule, S; Matthews, T | 1 |
| Emko, P; Kent, PF; Kurtz, DB; White, TL | 1 |
| Benavente, I; Errea, JM; Gazulla, J; Tordesillas, CJ | 1 |
| Hevia, A; Hinchey, P; Hobgood, C | 1 |
| Mascalzi, MG; Raudino, F; Zagami, A | 1 |
| Yatham, LN | 1 |
| Arcuri, E; Barbieri, M; Bonezzi, C; Caraceni, A; De Conno, F; Gorni, G; Maltoni, M; Martini, C; Tirelli, W; Visentin, M; Yaya Tur, R; Zecca, E | 1 |
| Ilag, VL | 1 |
| Karamanlioğlu, B; Memiş, D; Pamukçu, Z; Turan, A; Yağiz, R; Yavuz, E | 1 |
| Allchorne, A; Decosterd, I; Woolf, CJ | 1 |
| Bach, FW; Jensen, TS; Rasmussen, PV; Sindrup, SH | 1 |
| Haanpää, M; Kujansuu, E; Mennander, S; Pirhonen, R; Puura, A; Rintala, S; Rorarius, MG; Salmelin, R; Suominen, P; Yli-Hankala, A | 1 |
| Bertelli, JA; Calixto, JB; Campos, MM; Ferreira, J; Rodrigues-Filho, R; Santos, AR | 1 |
| Hsu, C; Sliwa, JA | 1 |
| Lim, LS; Takahashi, PY | 1 |
| García-Regata, O; González-Macías, J; Hernández, JL; Jiménez, V; Pajarón, M; Ramos-Estébanez, C | 1 |
| Berkich, DA; Gruetter, R; Hutson, SH; Keiger, CJ; LaNoue, KF; Oz, G; Xu, Y | 1 |
| Lu, Y; Smiley, MM; Vera-Portocarrero, LP; Westlund, KN; Zidan, A | 1 |
| Papp, Z; Török, L | 1 |
| Gilron, I; Hansen, C; Hong, M | 1 |
| Elovic, E; Lombard, L; Zafonte, R | 1 |
| Luggen, AS | 1 |
| Aiyar, J; Anker, N; Belley, M; Bristow, L; Campbell, B; Cohen, C; Park, KT; Ren, K; Stearns, B; Urban, MO | 1 |
| Dos Santos, RG; Dotsikas, I; Felix, R; Kolocouris, N; Papadopoulou-Daifoti, Z; Papanastasiou, I; Sandoval, A; Vamvakides, A; Zoidis, G | 1 |
| Behar, KL; de Graaf, RA; Mason, GF; Patel, AB; Rothman, DL; Shulman, RG | 1 |
| Daikhin, Y; Horyn, O; Lazarow, A; Luhovyy, B; Nissim, I; Wehrli, S; Yudkoff, M | 1 |
| Höfner, G; Kragler, A; Wanner, KT | 1 |
| Berrino, L; de Novellis, V; Maione, S; Marabese, I; Mariani, L; Oliva, P; Palazzo, E; Rossi, F; Scafuro, M; Siniscalco, D | 1 |
| Lebon, V; Mason, GF; Petersen, KF; Rothman, DL; Shulman, GI | 1 |
| Bacher, J; Li, SS; Shen, J; Yang, J | 1 |
| Carvalho, RA; Cunha, RA; Duarte, JM | 1 |
| Behar, KL; Chowdhury, GM; Mason, GF; Patel, AB; Rothman, DL | 1 |
| Enrique Jiménez-Ferrer, J; Gutiérrez, C; Herrera-Ruiz, M; León, I; Mirón, G; Tortoriello, J | 1 |
| Bernal, J; Cuadrado, M; Manzano, J; Morte, B | 1 |
| Behar, KL; Chowdhury, GM; Gibson, KM; Gupta, M; Patel, AB | 1 |
| Carpentier, P; Dorandeu, F; Fauvelle, F; Foquin, A; Graveron-Demilly, D; Rabeson, H; Testylier, G; van Ormondt, D | 1 |
| Bak, LK; Leke, R; Schousboe, A; Waagepetersen, HS | 1 |
| Castro, MM; Cerdán, S; Fonseca, CP; Geraldes, CF; Sierra, A | 1 |
| Ernest, NJ; Habela, CW; Sontheimer, H; Swindall, AF | 1 |
| Shen, J; Yang, J | 1 |
| Fang, D; Guo, L; Lian, Y; Zhao, G; Zhao, X; Zhou, J; Zhuang, W | 1 |
| Andrade, A; Campbell, KP; Felix, R; González-Ramírez, R; Lipscombe, D; Sandoval, A | 1 |
| Eyjolfsson, EM; Nilsen, LH; Schousboe, A; Schousboe, I; Smeland, OB; Sonnewald, U; Waagepetersen, HS; Walls, AB | 1 |
| Bak, LK; Iversen, P; Keiding, S; Leke, R; Ott, P; Portela, LV; Schousboe, A; Sørensen, M; Vilstrup, H; Waagepetersen, HS | 1 |
| Baverel, G; El Hage, M; Ferrier, B; Martin, G | 1 |
| Patel, AB; Shameem, M | 1 |
| Götz, J; Ittner, LM; Nilsen, LH; Rae, C; Sonnewald, U | 1 |
| Choi, EJ; Jeon, CO; Jeong, SH; Jung, JY; Lee, SH | 1 |
| Ambadipudi, S; Patel, AB; Tiwari, V | 1 |
| Patel, AB; Subramaniam, V; Tiwari, V; Veeraiah, P | 1 |
| Linde, M; Steiner, TJ | 1 |
| Côté, MP; Gandhi, S; Houlé, JD; Zambrotta, M | 1 |
| Imamura, Y; Iwata, K; Kita, K; Kobayashi, M; Nakaya, Y; Okada-Ogawa, A; Sessle, BJ; Shinoda, M | 1 |
| Garraway, SM; Grau, JW; Huang, YJ; Lee, KH; Murphy, L | 1 |
| Hertz, L; Rothman, DL | 1 |
| Mokrousov, IS; Perfilova, VN; Popova, TA; Prokofiev, II; Tyurenkov, IN; Vasil'eva, OS; Vodopyanova, EG | 1 |
| Eshghi, S; Guillén, F; Habibi, F; Rahemi, M; Ramezanian, A; Serrano, M; Valero, D | 1 |
| Guillén, F; Habibi, F; Ramezanian, A; Serrano, M; Valero, D | 1 |
| Bjørkmo, M; Chaudhry, FA; Gundersen, V; Hassel, B; Nordengen, K; Qureshi, T; Storm-Mathisen, J; Utheim, TP; Watne, LO | 1 |
| Ellis-Davies, GCR | 1 |
| Cataldo, PG; Hebert, EM; Saavedra, L; Savoy de Giori, G; Villegas, JM | 1 |
| Asghari, M; Farokhzad, A; Mahna, N; Soleimani Aghdam, M; Vaezi, S | 1 |
| Fan, Y; Ge, Y; Guo, M; Huang, R; Li, C; Sun, L; Wu, Y; Zhu, J | 1 |
| Kobayashi, Y; Koike, S; Miura, H; Shimamoto, S; Suzuki, Y; Yamada, H | 1 |
218 review(s) available for phenyl acetate and gamma-aminobutyric acid
| Article | Year |
|---|---|
GABAA agonists as targets for drug development.
Topics: Acetates; Acrylates; Amines; Analgesics; Anthelmintics; Anticonvulsants; Bicuculline; Computer Simulation; Cyclohexanecarboxylic Acids; Cyclopentanes; Drug Design; Gabapentin; gamma-Aminobutyric Acid; Isoxazoles; Molecular Conformation; Molecular Weight; Receptors, GABA-A | 1992 |
Gabapentin.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Drugs, Investigational; Electroencephalography; Epilepsy; Evoked Potentials; Gabapentin; gamma-Aminobutyric Acid; Humans | 1991 |
Antiepileptic medications in development.
Topics: Acetates; Amines; Aminocaproates; Animals; Anticonvulsants; Chemistry, Pharmaceutical; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Evaluation, Preclinical; Drugs, Investigational; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin | 1991 |
[Current viewpoints in the treatment of epilepsies: role of new antiepileptics?].
Topics: 4-Aminobutyrate Transaminase; Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Drug Tolerance; Enzyme Inhibitors; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Triazines; Vigabatrin | 1995 |
Mechanisms of action of currently prescribed and newly developed antiepileptic drugs.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Drugs, Investigational; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Mice; Phenylcarbamates; Propylene Glycols; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Triazines; Valproic Acid | 1994 |
Emerging perspectives on the mechanism of action of gabapentin.
Topics: Acetates; Amines; Amino Acids; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Leucine; Neurotransmitter Agents; Receptors, Neurotransmitter | 1994 |
Antiepileptic drug mechanisms of action.
Topics: Acetates; Action Potentials; Amines; Anticonvulsants; Calcium Channels; Cyclohexanecarboxylic Acids; Drug Design; Epilepsy, Generalized; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Receptors, GABA-A; Receptors, Neurotransmitter; Sodium Channels; Triazines; Valproic Acid | 1993 |
Gabapentin. A review of its pharmacological properties and clinical potential in epilepsy.
Topics: Acetates; Amines; Animals; Anticonvulsants; Biological Availability; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Tolerance; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Tissue Distribution | 1993 |
[New antiepileptic medications].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Triazines; Vigabatrin; Zonisamide | 1995 |
Adjunctive therapy in epilepsy: a cost-effectiveness comparison of alternative treatment options.
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Clobazam; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Decision Support Techniques; Drug Therapy, Combination; Drug Tolerance; Electroencephalography; Epilepsy; Evoked Potentials; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Long-Term Care; Triazines; Vigabatrin | 1995 |
New antiepileptic drugs--an explosion of activity.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Approval; Drug Interactions; Drug Therapy, Combination; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Product Surveillance, Postmarketing; Treatment Outcome; Triazines; Vigabatrin | 1995 |
New antiepileptic drugs for children: felbamate, gabapentin, lamotrigine, and vigabatrin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Approval; Epilepsies, Partial; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; United States; United States Food and Drug Administration; Vigabatrin | 1994 |
Gabapentin: a new agent for the management of epilepsy.
Topics: Acetates; Adult; Age Factors; Amines; Anticonvulsants; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsies, Partial; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Randomized Controlled Trials as Topic | 1994 |
Mechanisms of action of new antiepileptic drugs: rational design and serendipitous findings.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin | 1994 |
Gabapentin.
Topics: Acetates; Adult; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 1994 |
Newer antiepileptic drugs. Towards an improved risk-benefit ratio.
Topics: Acetamides; Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Piracetam; Propylene Glycols; Risk Factors; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 1994 |
New anti-epileptic drugs in the 1990s.
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Clobazam; Cyclohexanecarboxylic Acids; Drugs, Investigational; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin | 1994 |
Guidelines for treating epilepsy in the age of felbamate, vigabatrin, lamotrigine, and gabapentin.
Topics: Acetates; Adult; Amines; Animals; Anticonvulsants; Child; Clinical Protocols; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines | 1994 |
Phenobarbitone to gabapentin: a guide to 82 years of anti-epileptic drug pharmacokinetic interactions.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Metabolic Clearance Rate; Phenobarbital | 1994 |
Clinical pharmacokinetics of gabapentin.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 1994 |
Clinical efficacy and safety of gabapentin.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsies, Partial; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Randomized Controlled Trials as Topic | 1994 |
Gabapentin: discussion.
Topics: Acetates; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drugs, Investigational; Epilepsies, Partial; Epilepsy, Absence; Epilepsy, Complex Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Neural Pathways; Treatment Outcome; Trigeminal Nuclei | 1994 |
Drug therapy for epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Decision Trees; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Patient Education as Topic; Phenylcarbamates; Propylene Glycols; Triazines | 1994 |
Antiepileptic drugs in development: prospects for the near future.
Topics: Acetates; Adult; Amines; Aminocaproates; Animals; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Approval; Drug Design; Drugs, Investigational; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin; Zonisamide | 1994 |
New antiepileptic drugs.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Randomized Controlled Trials as Topic; Tiagabine; Topiramate; Triazines; Vigabatrin | 1994 |
Advances in pharmacotherapy: recent developments in the treatment of epilepsy.
Topics: Acetates; Amines; Aminocaproates; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin | 1993 |
Antiepileptic drugs in clinical development.
Topics: Acetates; Amines; Aminocaproates; Anticonvulsants; Brain; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Structure-Activity Relationship; Synaptic Transmission; Tiagabine; Topiramate; Triazines; Vigabatrin | 1993 |
[Diagnosis and therapy of epilepsy and myoclonus].
Topics: Acetates; Amines; Cerebral Cortex; Cyclohexanecarboxylic Acids; Electrophysiology; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Myoclonus; Phenytoin | 1993 |
Advances in the pharmacotherapy of epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines | 1993 |
Comparative pharmacokinetics of the newer antiepileptic drugs.
Topics: Acetamides; Acetates; Amines; Aminocaproates; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dioxolanes; Felbamate; Flunarizine; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin | 1993 |
[Refractory epilepsy in adults and the new antiepileptic drugs: the role of gabapentin].
Topics: Acetates; Amines; Anticonvulsants; Chile; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Resistance; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 1995 |
Potential use of gabapentin and lamotrigine.
Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drugs, Investigational; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines | 1995 |
[Gabapentin (Neurontin): a new possibility in the add-on therapy of partial epilepsies].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Multicenter Studies as Topic; Randomized Controlled Trials as Topic | 1996 |
Clinical efficacy of new antiepileptic drugs in refractory partial epilepsy: experience in the United States with three novel drugs.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsies, Partial; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Phenylcarbamates; Placebos; Propylene Glycols; Randomized Controlled Trials as Topic; Topiramate; Treatment Outcome; United States | 1996 |
Pharmacokinetic profile of topiramate in comparison with other new antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines; Vigabatrin | 1996 |
Utilization of new antiepileptic drugs in children.
Topics: Acetates; Adolescent; Adult; Age Factors; Amines; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin | 1996 |
[Advances in the diagnostic and treatment of infantile epilepsy].
Topics: Acetates; Amines; Anticonvulsants; Brain; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Electroencephalography; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Magnetic Resonance Imaging; Phenylcarbamates; Propylene Glycols; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; Triazines; Vigabatrin | 1996 |
Gabapentin: pharmacokinetics, efficacy, and safety.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans | 1995 |
[Current anti-epilepsy drugs].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin | 1995 |
Mechanisms of action of antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; N-Methylaspartate; Neural Pathways; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Valproic Acid | 1995 |
Antiepileptic drug mechanisms of action.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Calcium Channels; Carbamazepine; Central Nervous System; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Phenytoin; Rats; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium Channels; Triazines; Trimethadione; Valproic Acid; Vigabatrin | 1995 |
Gabapentin.
Topics: Acetates; Adult; Amines; Animals; Anticonvulsants; Child; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregnancy; Treatment Outcome | 1995 |
Clinical pharmacokinetics of newer antiepileptic drugs. Lamotrigine, vigabatrin, gabapentin and oxcarbazepine.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Tissue Distribution; Triazines; Vigabatrin | 1996 |
A cost minimization study comparing vigabatrin, lamotrigine and gabapentin for the treatment of intractable partial epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Cost Control; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Vigabatrin | 1996 |
Important pharmacokinetic properties of antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Biopharmaceutics; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Intestinal Absorption; Lamotrigine; Oxcarbazepine; Topiramate; Triazines; Vigabatrin | 1995 |
Seizure control: how to use the new antiepileptic drugs in older patients.
Topics: Acetates; Age Factors; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Monitoring; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Patient Selection; Seizures; Triazines; Vigabatrin | 1996 |
New antiepileptic drugs. II. Clinical use.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Felbamate; Forecasting; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines; Vigabatrin; Zonisamide | 1996 |
Diagnosis and treatment of epilepsy in children and adolescents.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Infant, Newborn; Lamotrigine; Triazines | 1996 |
Periodic limb movements of sleep and the restless legs syndrome.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Folic Acid; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Narcotics; Polysomnography; Restless Legs Syndrome; Sleep Wake Disorders; Vitamin E; Wakefulness | 1996 |
New antiepileptic drugs: a systematic review of their efficacy and tolerability.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Child; Cross-Over Studies; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Male; Middle Aged; Nipecotic Acids; Randomized Controlled Trials as Topic; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Zonisamide | 1996 |
Update on the mechanism of action of antiepileptic drugs.
Topics: 4-Aminobutyrate Transaminase; Acetamides; Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Membrane Potentials; Mice; Neurotransmitter Agents; Nipecotic Acids; Phenethylamines; Phenylcarbamates; Propylene Glycols; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tiagabine; Topiramate; Triazines; Vigabatrin | 1996 |
Pharmacokinetics of new antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Carbamazepine; Cyclohexanecarboxylic Acids; Enzyme Induction; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin | 1996 |
Clinical administration of new antiepileptic drugs: an overview of safety and efficacy.
Topics: Acetates; Amines; Anticonvulsants; Confidence Intervals; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Odds Ratio; Placebos; Randomized Controlled Trials as Topic; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide | 1996 |
The role of the old and the new antiepileptic drugs in special populations: mental and multiple handicaps.
Topics: Acetates; Amines; Anticonvulsants; Cerebral Palsy; Cyclohexanecarboxylic Acids; Disabled Persons; Drug Administration Schedule; Drug Interactions; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Phenylcarbamates; Polypharmacy; Propylene Glycols; Vigabatrin | 1996 |
[Advantages and disadvantages of new antiepileptic drugs].
Topics: Acetates; Adrenocorticotropic Hormone; Amines; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Valproic Acid; Vigabatrin | 1996 |
[Treatment of the epilepsy: new drugs].
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines; Vigabatrin; Zonisamide | 1996 |
The new antiepileptic drugs.
Topics: Abnormalities, Drug-Induced; Acetates; Adolescent; Adult; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Pregnancy; Propylene Glycols; Randomized Controlled Trials as Topic; Triazines; Vigabatrin | 1996 |
New antiepileptic drugs.
Topics: Acetates; Adult; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines; Vigabatrin | 1996 |
New antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin | 1996 |
Pharmacokinetics and interaction profile of topiramate: review and comparison with other newer antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Monitoring; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Topiramate; Triazines; Vigabatrin | 1997 |
Overview of the safety of newer antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin | 1997 |
[New antiepileptic drugs].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Phenylcarbamates; Propylene Glycols; Vigabatrin | 1997 |
Pharmacologic and dietary therapies in epilepsy: conventional treatments and recent advances.
Topics: Acetates; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketone Bodies; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Triazines; Valproic Acid; Vigabatrin | 1997 |
Recent advancements in epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Neurosurgery; Phenylcarbamates; Phenytoin; Pia Mater; Propylene Glycols; Temporal Lobe; Topiramate; Triazines; Vigabatrin | 1997 |
Use of gabapentin in pain management.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Migraine Disorders; Pain | 1997 |
A review of the newer antiepileptic drugs and the ketogenic diet.
Topics: Acetates; Age Factors; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Ketone Bodies; Lamotrigine; Male; Phenylcarbamates; Propylene Glycols; Seizures; Triazines | 1997 |
Gabapentin for treatment of epilepsy in children.
Topics: Acetates; Adolescent; Adult; Amines; Animals; Anticonvulsants; Child; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Disease Models, Animal; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 1997 |
Overview of lamotrigine and the new antiepileptic drugs: the challenge.
Topics: Acetates; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Exanthema; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Treatment Outcome; Triazines; Valproic Acid; Vigabatrin | 1997 |
Mood stabilizer combinations: a review of safety and efficacy.
Topics: Acetates; Amines; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Calcium Channel Blockers; Clinical Trials as Topic; Clozapine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium; Risperidone; Valproic Acid | 1998 |
Newer antiepileptic drugs: gabapentin, lamotrigine, felbamate, topiramate and fosphenytoin.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Topiramate; Triazines | 1998 |
Advances in the medical treatment of epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Diazepam; Drug Approval; Drug Design; Drug Interactions; Drug Resistance; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Ketones; Lamotrigine; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Phenylcarbamates; Phenytoin; Prodrugs; Propylene Glycols; Tiagabine; Topiramate; Triazines; United States; Valproic Acid; Vigabatrin | 1998 |
A summary of mechanistic hypotheses of gabapentin pharmacology.
Topics: Acetates; Amines; Analgesics; Animals; Anti-Anxiety Agents; Anticonvulsants; Brain; Calcium Channels; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Models, Neurological; Neuroprotective Agents; Neurotransmitter Agents; Pain; Sodium Channels; Synapses; Tissue Distribution | 1998 |
Measuring human brain GABA in vivo: effects of GABA-transaminase inhibition with vigabatrin.
Topics: 4-Aminobutyrate Transaminase; Acetates; Amines; Anticonvulsants; Brain; Brain Chemistry; Cyclohexanecarboxylic Acids; Enzyme Inhibitors; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Models, Neurological; Vigabatrin | 1998 |
Anticonvulsant therapy in small animals.
Topics: Acetates; Amines; Animals; Anticonvulsants; Bromides; Clonazepam; Clorazepate Dipotassium; Cyclohexanecarboxylic Acids; Diazepam; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Mephenytoin; Pentobarbital; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Seizures; Valproic Acid | 1998 |
Monotherapy clinical trials of new antiepileptic drugs: design, indications, and controversies.
Topics: Acetates; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Approval; Drug Design; Drug Therapy, Combination; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Placebos; Research Design; Treatment Failure; Treatment Outcome; United States; United States Food and Drug Administration | 1997 |
The new antiepileptic drugs: a systematic review of their efficacy and tolerability.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Male; Middle Aged; Randomized Controlled Trials as Topic; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Zonisamide | 1997 |
Antiepileptic drug review: part 2.
Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Cyclohexanecarboxylic Acids; Drug Interactions; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Topiramate; Triazines | 1998 |
Aggravation of focal epileptic seizures by antiepileptic drugs.
Topics: Acetates; Acute Disease; Adult; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Epilepsies, Partial; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Phenylcarbamates; Propylene Glycols; Vigabatrin | 1998 |
A mechanistic approach to antiepileptic drug interactions.
Topics: Acetates; Amines; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cyclohexanecarboxylic Acids; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Glucuronosyltransferase; Humans; Lamotrigine; Mixed Function Oxygenases; Nipecotic Acids; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 1998 |
Special considerations: use of lithium in children, adolescents, and elderly populations.
Topics: Abnormalities, Drug-Induced; Acetates; Adolescent; Adult; Age Factors; Aged; Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Male; Pregnancy; Triazines; Valproic Acid | 1998 |
Anticonvulsants and antipsychotics in the treatment of bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines | 1998 |
Mechanisms of action of gabapentin.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Neurotransmitter Agents | 1997 |
New antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Approval; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; United States; Vigabatrin | 1998 |
Antiepileptic drug therapy.
Topics: Acetates; Amines; Animals; Anticonvulsants; Bromides; Cat Diseases; Cats; Cyclohexanecarboxylic Acids; Diazepam; Dog Diseases; Dogs; Drug Resistance; Emergency Treatment; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Phenobarbital; Phenylcarbamates; Potassium Compounds; Propylene Glycols; Seizures | 1998 |
Cellular and molecular actions of lamotrigine: Possible mechanisms of efficacy in bipolar disorder.
Topics: Acetates; Action Potentials; Amines; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Calcium Channel Blockers; Carrier Proteins; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Lamotrigine; Limbic System; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neural Inhibition; Neuronal Plasticity; Serotonin Plasma Membrane Transport Proteins; Signal Transduction; Sodium Channels; Synaptic Transmission; Triazines; Valproic Acid | 1998 |
Gabapentin. Antiepileptic mechanism of action.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Calcium Channels; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Neural Inhibition; Receptors, GABA; Receptors, Glutamate; Sodium Channels; Synaptic Transmission | 1998 |
Lamotrigine and gabapentin. Alternative in the treatment of bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Treatment Outcome; Triazines | 1998 |
Fortnightly review: drug treatment of epilepsy.
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Clobazam; Clonazepam; Cyclohexanecarboxylic Acids; Diethylcarbamazine; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Topiramate; Valproic Acid; Vigabatrin | 1999 |
New medication options for patients with epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines | 1998 |
Neuropharmacologic aspects of the ocular motor system and the treatment of abnormal eye movements.
Topics: Abducens Nerve; Acetates; Amines; Baclofen; Cranial Nerve Diseases; Cyclohexanecarboxylic Acids; Eye Movements; Fixation, Ocular; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypoglossal Nerve; Ocular Motility Disorders; Vestibular Nerve; Visual Pathways | 1999 |
3-substituted GABA analogs with central nervous system activity: a review.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Structure-Activity Relationship | 1999 |
Carrell-Krusen Symposium invited lecture. Clinical trials in motor neuron diseases.
Topics: Acetates; Adolescent; Adult; Amines; Amyotrophic Lateral Sclerosis; Animals; Brain-Derived Neurotrophic Factor; Child; Child, Preschool; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Guidelines as Topic; Humans; Infant; Insulin-Like Growth Factor I; Male; Mice; Middle Aged; Motor Neuron Disease; Muscular Atrophy, Spinal; Nerve Growth Factors; Outcome Assessment, Health Care; Postpoliomyelitis Syndrome; Riluzole | 1999 |
Gabapentin: a review of published experience in the treatment of bipolar disorder and other psychiatric conditions.
Topics: Acetates; Amines; Anticonvulsants; Anxiety; Bipolar Disorder; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Psychotic Disorders; Substance-Related Disorders | 1999 |
New antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Monitoring; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Practice Guidelines as Topic; Topiramate; Triazines; Vigabatrin | 1999 |
New antiepileptic drugs: comparison of key clinical trials.
Topics: Acetates; Amines; Anticonvulsants; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind Method; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Placebos; Research Design; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin | 1999 |
A new twist for stopping the shakes? Revisiting GABAergic therapy for essential tremor.
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Primidone; Propranolol; Tremor | 1999 |
Treatment of chronic pain with antiepileptic drugs: a new era.
Topics: Acetates; Amines; Analgesics; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neurons, Afferent; Nociceptors; Pain; Receptors, Opioid; Spinal Nerve Roots | 1999 |
Clinical experience using adjunctive gabapentin in treatment-resistant bipolar mixed states.
Topics: Acetates; Adjuvants, Pharmaceutic; Adult; Aged; Amines; Analysis of Variance; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Drug Resistance; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Treatment Outcome | 1999 |
Mechanisms of new antiepileptic drugs.
Topics: Acetates; Amines; Animals; Anticonvulsants; Brain; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Drug Industry; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Receptors, GABA; Receptors, GABA-A; Sodium Channel Blockers | 1999 |
Lamotrigine in the treatment of bipolar depression.
Topics: Acetates; Affect; Amines; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cross-Over Studies; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Randomized Controlled Trials as Topic; Triazines | 1999 |
Options after the first antiepileptic drug has failed.
Topics: Acetates; Amines; Anticonvulsants; Attitude to Health; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Quality of Life; Treatment Failure; Treatment Outcome; Valproic Acid; Vigabatrin | 1999 |
Monotherapy trials with gabapentin for partial epilepsy.
Topics: Acetates; Ambulatory Care; Amines; Anticonvulsants; Carbamazepine; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Hospitalization; Humans; Multicenter Studies as Topic; Placebos; Randomized Controlled Trials as Topic; Treatment Outcome | 1999 |
Monostars: an aid to choosing an antiepileptic drug as monotherapy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Practice Patterns, Physicians'; Triazines; Valproic Acid; Vigabatrin | 1999 |
Use of new antiepileptic drugs in the treatment of childhood epilepsy.
Topics: Acetates; Adult; Age Factors; Amines; Anticonvulsants; Child; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Spasms, Infantile; Tiagabine; Topiramate; Triazines; Vigabatrin | 1999 |
Gabapentin in the management of convulsive disorders.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Gabapentin; gamma-Aminobutyric Acid; Humans; Rats; Synaptic Transmission; Treatment Outcome | 1999 |
Postherpetic neuralgia: role of gabapentin and other treatment modalities.
Topics: Acetates; Administration, Topical; Age Factors; Aged; Ambulatory Care; Amines; Analgesics; Anticonvulsants; Antidepressive Agents, Tricyclic; Capsaicin; Carbamazepine; Clinical Trials as Topic; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; Middle Aged; Narcotics; Neuralgia; Pain; Risk Factors; Severity of Illness Index; Treatment Outcome | 1999 |
Social phobia: issues in assessment and management.
Topics: Acetates; Amines; Anticonvulsants; Benzodiazepines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Monoamine Oxidase Inhibitors; Personality Inventory; Phobic Disorders; Psychiatric Status Rating Scales; Psychometrics; Selective Serotonin Reuptake Inhibitors | 1999 |
Nonepileptic uses of gabapentin.
Topics: Acetates; Amines; Analgesics; Antimanic Agents; Antiparkinson Agents; Bipolar Disorder; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Gabapentin; gamma-Aminobutyric Acid; Humans; Movement Disorders; Neuralgia; Restless Legs Syndrome; Spinal Cord Diseases; Treatment Outcome | 1999 |
Evidence-based medicine and antiepileptic drugs.
Topics: Acetates; Adult; Amines; Anticonvulsants; Confidence Intervals; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Electric Stimulation Therapy; Epilepsies, Partial; Evidence-Based Medicine; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Odds Ratio; Randomized Controlled Trials as Topic; Tiagabine; Topiramate; Triazines; Vagus Nerve | 1999 |
Gabapentin.
Topics: Acetates; Amines; Anticonvulsants; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dizziness; Drug Monitoring; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Product Surveillance, Postmarketing; Sleep Wake Disorders; Treatment Outcome | 1999 |
Therapeutic advances: new hope for patients with ALS.
Topics: Acetates; Aged; Amines; Amyotrophic Lateral Sclerosis; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Long-Term Care; Neuroprotective Agents; Patient Education as Topic; Riluzole | 1998 |
Managing pediatric epilepsy syndromes with new antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin | 1999 |
Voltage-dependent Ca2+ channel alpha2delta auxiliary subunit: structure, function and regulation.
Topics: Acetates; Amines; Animals; Calcium Channels; Cloning, Molecular; Cyclohexanecarboxylic Acids; Electrochemistry; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Kinetics; Models, Molecular; Protein Structure, Quaternary; Recombinant Proteins | 1999 |
Gabapentin and lamotrigine in bipolar disorder.
Topics: Acetates; Adult; Amines; Anticonvulsants; Bipolar Disorder; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Triazines | 1999 |
The clinical pharmacokinetics of the new antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Zonisamide | 1999 |
[Gabapentin in the treatment of polyneuropathy associated with the human immunodeficiency virus].
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; HIV Infections; HIV-1; Humans; Male; Polyneuropathies; Remission Induction | 1999 |
Interstitial cystitis and the potential role of gabapentin.
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Cystitis, Interstitial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain; Pain Clinics | 2000 |
Mood stabilizers during breastfeeding: a review.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Breast Feeding; Carbamazepine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Infant, Newborn; Lamotrigine; Lithium; MEDLINE; Milk, Human; Pregnancy; Pregnancy Complications; Puerperal Disorders; Triazines; Valproic Acid | 2000 |
[GABA-ergic system and antiepileptic drugs].
Topics: Acetates; Amines; Anticonvulsants; Binding, Competitive; Calcium Channels; Chloride Channels; Cyclohexanecarboxylic Acids; Epilepsy; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Humans; Nipecotic Acids; Receptors, GABA; Sodium Channels; Tiagabine; Vigabatrin | 2000 |
Gabapentin for drug-resistant partial epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Treatment Failure | 2000 |
Gabapentin: a new tool in the treatment of neuropathic pain.
Topics: Acetates; Amines; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Treatment Outcome | 1999 |
New antiepileptic drugs.
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2000 |
Use of gabapentin in the treatment of neuropathic pain.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia | 2000 |
Tremor-predominant Parkinson's disease. Approaches to treatment.
Topics: Acetates; Amantadine; Amines; Antiparkinson Agents; Botulinum Toxins; Cholinergic Antagonists; Clonazepam; Clozapine; Cyclohexanecarboxylic Acids; Dopamine Agonists; Electric Stimulation Therapy; Gabapentin; Gamma Rays; gamma-Aminobutyric Acid; Globus Pallidus; Humans; Neurosurgical Procedures; Parkinson Disease; Propranolol; Radiosurgery; Thalamus; Tremor | 2000 |
Gabapentin use in neuropathic pain syndromes.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Peripheral Nervous System Diseases; Proto-Oncogene Mas; Syndrome | 2000 |
[Current data on gabapentin].
Topics: Acetates; Adult; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Tolerance; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Treatment Outcome | 2000 |
Gabapentin add-on for drug-resistant partial epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Resistance; Drug Therapy, Combination; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Treatment Failure | 2000 |
Adjuvant therapy of melanoma with interferon-alpha-2b is associated with mania and bipolar syndromes.
Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Antimanic Agents; Antineoplastic Agents; Bipolar Disorder; Chemotherapy, Adjuvant; Cyclohexanecarboxylic Acids; Depression; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Interferon alpha-2; Interferon-alpha; Male; Melanoma; Middle Aged; Mood Disorders; Prospective Studies; Recombinant Proteins | 2000 |
Gabapentin in pain management.
Topics: Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain | 2000 |
Drug treatment of benign focal epilepsies of childhood.
Topics: Acetates; Amines; Anticonvulsants; Child; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Thiazines; Time Factors; Treatment Outcome | 2000 |
Painful trigeminal neuropathy caused by severe mandibular resorption and nerve compression in a patient with systemic sclerosis: case report and literature review.
Topics: Acetates; Adult; Amines; Analgesics; Anticonvulsants; Bone Resorption; CREST Syndrome; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mandibular Diseases; Mandibular Nerve; Nerve Compression Syndromes; Trigeminal Neuralgia | 2000 |
Therapeutic safety monitoring: what to look for and when to look for it.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Monitoring; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Topiramate; Triazines; Valproic Acid; Vigabatrin | 2000 |
[Adverse effects of antiepileptic agents].
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Clobazam; Cyclohexanecarboxylic Acids; Drug Utilization; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Norway; Piracetam; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2000 |
New treatments of bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Antimanic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Olanzapine; Phenytoin; Pirenzepine; Topiramate; Treatment Outcome; Triazines | 1999 |
New antiepileptic drugs and preparations.
Topics: Acetates; Administration, Rectal; Age Factors; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Diazepam; Drug Overdose; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Topiramate; Triazines; Valproic Acid | 2000 |
An ever-increasing pharmacopoeia for the management of patients with bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Clozapine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Electroconvulsive Therapy; Electromagnetic Phenomena; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Olanzapine; Pirenzepine; Risperidone; Topiramate; Treatment Outcome; Triazines; Valproic Acid | 2000 |
[Gabapentin--yet another antiepileptic agent for the treatment of neuropathic pain?].
Topics: Acetates; Amines; Analgesics; Anticonvulsants; Clinical Trials as Topic; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Herpesviridae Infections; Humans; Multicenter Studies as Topic; Neuralgia | 2001 |
Pharmacotherapy of spasticity: oral medications and intrathecal baclofen.
Topics: Acetates; Administration, Oral; Amines; Anti-Anxiety Agents; Baclofen; Benzodiazepines; Cerebral Palsy; Child, Preschool; Cyclohexanecarboxylic Acids; Dantrolene; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Muscle Relaxants, Central | 2001 |
[Gabapentin therapy for pain].
Topics: Acetates; Amines; Analgesics; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Migraine Disorders; Pain; Reflex Sympathetic Dystrophy; Trigeminal Neuralgia | 2001 |
Novel treatments for bipolar disorder.
Topics: Acetates; Amines; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Fatty Acids, Omega-3; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Topiramate; Triazines; Valproic Acid | 2001 |
Effects of antimanic mood-stabilizing drugs on fetuses, neonates, and nursing infants.
Topics: Abnormalities, Drug-Induced; Acetates; Adult; Amines; Antimanic Agents; Benzodiazepines; Breast Feeding; Carbamazepine; Cyclohexanecarboxylic Acids; Female; Fetus; Gabapentin; gamma-Aminobutyric Acid; Haloperidol; Humans; Infant, Newborn; Lithium; Mood Disorders; Olanzapine; Pirenzepine; Placenta; Pregnancy; Risk Factors; Valproic Acid | 2001 |
Evidence for the use of gabapentin in the treatment of diabetic peripheral neuropathy.
Topics: Acetates; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Humans | 2001 |
Cognitive side effects of anticonvulsants.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cognition Disorders; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Mood Disorders; Topiramate; Triazines; Valproic Acid | 2001 |
In vivo nuclear magnetic resonance studies of glutamate-gamma-aminobutyric acid-glutamine cycling in rodent and human cortex: the central role of glutamine.
Topics: Acetates; Animals; Astrocytes; Biological Transport; Blood-Brain Barrier; Carbon Isotopes; Cerebral Cortex; Disease Models, Animal; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Humans; Hyperammonemia; Magnetic Resonance Spectroscopy; Neurons; Nitrogen Isotopes; Rats | 2001 |
Gabapentin treatment for bipolar disorders.
Topics: Acetates; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Randomized Controlled Trials as Topic; Treatment Outcome | 2001 |
GABA agonists and gabapentin for spastic hypertonia.
Topics: Acetates; Amines; Animals; Anticonvulsants; Baclofen; Benzodiazepines; Cyclohexanecarboxylic Acids; Diazepam; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Muscle Spasticity | 2001 |
Gabapentin: a unique anti-epileptic agent.
Topics: Acetates; Adult; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Complex Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia | 2001 |
Gabapentin for neuropathic pain: systematic review of controlled and uncontrolled literature.
Topics: Acetates; Amines; Analgesics; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Randomized Controlled Trials as Topic; Treatment Outcome | 2001 |
[Gabapentin for therapy of neuropathic pain].
Topics: Acetates; Amines; Animals; Biological Availability; Brain; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pain Threshold; Spinal Cord | 2001 |
Complex regional pain syndrome.
Topics: Acetates; Algorithms; Amines; Anesthesia, Conduction; Anesthetics, Local; Anti-Inflammatory Agents; Antidepressive Agents; Autonomic Nerve Block; Complex Regional Pain Syndromes; Cyclohexanecarboxylic Acids; Decision Trees; Electromyography; Gabapentin; gamma-Aminobutyric Acid; Humans; Patient Care Team; Patient Selection; Physical Therapy Modalities; Referral and Consultation; Thermography; Treatment Outcome | 2002 |
Management of spasticity, pain, and paroxysmal phenomena in multiple sclerosis.
Topics: Acetates; Amines; Autoimmune Diseases; Baclofen; Benzodiazepines; Botulinum Toxins, Type A; Cannabinoids; Causalgia; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Dystonia; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Mechanoreceptors; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Pain; Physical Therapy Modalities; Receptors, GABA-A; Receptors, GABA-B; Relaxation Therapy; Trigeminal Neuralgia | 2001 |
Bipolar disorders and the effectiveness of novel anticonvulsants.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Randomized Controlled Trials as Topic; Topiramate; Triazines | 2002 |
The evolving role of topiramate among other mood stabilizers in the management of bipolar disorder.
Topics: Acetates; Acute Disease; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Randomized Controlled Trials as Topic; Topiramate; Triazines; Valproic Acid | 2001 |
Gabapentin: pharmacology and its use in pain management.
Topics: Acetates; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Nervous System Diseases; Pain; Pilot Projects; Pregnancy; Randomized Controlled Trials as Topic | 2002 |
Lamotrigine update and its use in mood disorders.
Topics: Acetates; Aggression; Amines; Antidepressive Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Depressive Disorder; Dermatitis, Exfoliative; Dizziness; Drug Interactions; Epilepsy; Exanthema; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Ion Channel Gating; Lamotrigine; Mood Disorders; Nausea; Randomized Controlled Trials as Topic; Sodium Channels; Triazines | 2002 |
Third generation anticonvulsants in bipolar disorder: a review of efficacy and summary of clinical recommendations.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Double-Blind Method; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Placebos; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide | 2002 |
Pharmacokinetics of new anticonvulsants in psychiatry.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Mental Disorders; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Psychiatry; Tiagabine; Topiramate; Triazines | 1998 |
Anticonvulsants for neuropathic pain and detoxification.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Clonazepam; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Inactivation, Metabolic; Lamotrigine; Neuralgia; Phenytoin; Substance Withdrawal Syndrome; Triazines; Valproic Acid | 1998 |
Bipolar disorder: current treatments and new strategies.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Mood Disorders; Topiramate; Treatment Outcome; Treatment Refusal; Triazines | 1998 |
Panic disorder and social phobia: current treatments and new strategies.
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Panic Disorder; Phobic Disorders; Selective Serotonin Reuptake Inhibitors | 1998 |
Background and rationale for use of anticonvulsants in psychiatry.
Topics: Acetates; Amines; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; History, 20th Century; Humans; Mental Disorders; Pain; Psychiatry | 1998 |
Gabapentin. Pfizer.
Topics: Acetates; Amines; Analgesics; Animals; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Contraindications; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Structure-Activity Relationship | 2002 |
Newer antiepileptic drugs in bipolar disorder: rationale for use and role in therapy.
Topics: Acetates; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Topiramate; Treatment Outcome; Triazines | 2002 |
Ca2+ channels and epilepsy.
Topics: Acetates; Amines; Calcium Channels; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Mutation | 2002 |
Use of anticonvulsants for treatment of neuropathic pain.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nervous System Diseases; Pain; Phenytoin; Triazines; Zonisamide | 2002 |
Mode of action of gabapentin in chronic neuropathic pain syndromes. A short review about its cellular mechanisms in nociceptive neurotransmission.
Topics: Acetates; Amines; Animals; Biogenic Monoamines; Calcium Channels; Chronic Disease; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Peripheral Nervous System Diseases; Synaptic Transmission | 2002 |
How can physicians and their patients with ALS decide to use the newly-available treatments to slow disease progression?
Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Disease Progression; Gabapentin; gamma-Aminobutyric Acid; Growth Substances; Humans; Intercellular Signaling Peptides and Proteins; Neuroprotective Agents; Quality of Life; Riluzole; Sickness Impact Profile | 1999 |
[Characteristics and indications of gabapentin].
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Child; Child, Preschool; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged | 2002 |
Antiepileptic drug therapy for adults: when to initiate and how to choose.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Recurrence; Risk Factors; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide | 2002 |
The role of anticonvulsants in preventive migraine therapy.
Topics: Acetates; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Approval; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Migraine Disorders; Recurrence; Topiramate; Treatment Outcome; Valproic Acid | 2003 |
Gabapentin for the treatment of tremor.
Topics: Acetates; Adult; Aged; Amines; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Parkinson Disease; Treatment Outcome; Tremor | 2003 |
Absence seizures in children.
Topics: Acetates; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Valproic Acid | 2002 |
New antiepileptic drug therapies.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Phenytoin; Piracetam; Propylene Glycols; Thiazines; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2002 |
Gabapentin dosing for neuropathic pain: evidence from randomized, placebo-controlled clinical trials.
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Herpesviridae Infections; Humans; Neuralgia; Pain; Peripheral Nervous System Diseases; Randomized Controlled Trials as Topic; Syndrome | 2003 |
Antidepressant properties of anticonvulsant drugs for bipolar disorder.
Topics: Acetates; Affect; Amines; Anticonvulsants; Antidepressive Agents; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Topiramate; Triazines; Valproic Acid | 2003 |
Treatment and prevention of postherpetic neuralgia.
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Lidocaine; Neuralgia; Randomized Controlled Trials as Topic | 2003 |
The role of GABA in anxiety disorders.
Topics: Acetates; Amines; Anxiety Disorders; Benzodiazepines; Cyclohexanecarboxylic Acids; GABA Agents; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Nipecotic Acids; Receptors, GABA-A; Synaptic Transmission; Tiagabine | 2003 |
Treating bipolar depression.
Topics: Acetates; Affect; Amines; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Lithium Compounds; Nipecotic Acids; Olanzapine; Oxcarbazepine; Pirenzepine; Tiagabine; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Zonisamide | 2003 |
Clinical inquiries. What nonhormonal therapies are effective for postmenopausal vasomotor symptoms?
Topics: Acetates; Amines; Cimicifuga; Clonidine; Contraindications; Cyclohexanecarboxylic Acids; Estrogens, Non-Steroidal; Evidence-Based Medicine; Exercise; Female; Gabapentin; gamma-Aminobutyric Acid; Hormone Replacement Therapy; Hot Flashes; Humans; Isoflavones; Middle Aged; Phytoestrogens; Phytotherapy; Plant Preparations; Postmenopause; Practice Guidelines as Topic; Selective Serotonin Reuptake Inhibitors; Soybean Proteins | 2003 |
Alternatives to lithium and divalproex in the maintenance treatment of bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Calcium Channel Blockers; Carbamazepine; Clozapine; Cyclohexanecarboxylic Acids; Dibenzothiazepines; Donepezil; Fatty Acids, Omega-3; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Indans; Lamotrigine; Lithium Carbonate; Olanzapine; Piperazines; Piperidines; Pirenzepine; Quetiapine Fumarate; Risperidone; Thiazoles; Topiramate; Treatment Outcome; Triazines; Valproic Acid | 2003 |
The clinical use of gabapentin in bipolar spectrum disorders.
Topics: Acetates; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans | 2003 |
Cellular and molecular action of the putative GABA-mimetic, gabapentin.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Anxiety; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Neurotransmitter Agents; Pain; Rats; Seizures; Signal Transduction | 2003 |
The role of gabapentin in treating diseases with cutaneous manifestations and pain.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia; Pain; Skin Diseases | 2003 |
Neuropathic cranial pain.
Topics: Acetates; Amines; Analgesics; Analgesics, Non-Narcotic; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Fructose; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Lamotrigine; Nervous System Diseases; Phenytoin; Topiramate; Triazines | 2003 |
The use of gabapentin for the treatment of postherpetic neuralgia.
Topics: Acetates; Amines; Analgesics; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia; Pain Measurement | 2003 |
Gabapentin dosing in the treatment of epilepsy.
Topics: Acetates; Adult; Amines; Anticonvulsants; Child; Child, Preschool; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 2003 |
Tremor.
Topics: Acetates; Amines; Anticonvulsants; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Electromyography; Essential Tremor; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Levodopa; Motor Cortex; Muscle, Skeletal; Parkinson Disease; Posture; Primidone; Randomized Controlled Trials as Topic; Severity of Illness Index; Somatosensory Cortex; Topiramate; Tremor | 2003 |
Gabapentin and lamotrigine: novel antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Intestinal Absorption; Lamotrigine; Tissue Distribution; Triazines | 1995 |
Essential tremor: differential diagnosis and current therapy.
Topics: Acetates; Adrenergic beta-Antagonists; Amines; Anti-Dyskinesia Agents; Anticonvulsants; Benzodiazepines; Botulinum Toxins; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Electric Stimulation Therapy; Essential Tremor; Ethanol; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Primidone; Thalamus; Topiramate | 2003 |
Pharmacological treatment of social anxiety disorder: a meta-analysis.
Topics: Acetates; Amines; Anti-Anxiety Agents; Antidepressive Agents; Antimanic Agents; Anxiety Disorders; Calcium Channel Blockers; Clonazepam; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Monoamine Oxidase Inhibitors; Phenelzine; Phobic Disorders; Piperidines; Selective Serotonin Reuptake Inhibitors; Treatment Outcome | 2003 |
The ideal pharmacokinetic properties of an antiepileptic drug: how close does levetiracetam come?
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2003 |
Essential tremor: diagnosis and treatment.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Essential Tremor; Gabapentin; gamma-Aminobutyric Acid; Humans; Parkinson Disease; Primidone; Propranolol | 2003 |
Gabapentin: in postherpetic neuralgia.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia | 2003 |
Gabapentin: a viewpoint by Brett R. Stacey.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia | 2003 |
Gabapentin: a viewpoint by Ian Gilron.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain | 2003 |
Assessment and treatment of hot flushes and menopausal mood disturbance.
Topics: Acetates; Aging; Amines; Anti-Anxiety Agents; Cognition Disorders; Cyclohexanecarboxylic Acids; Female; Follicle Stimulating Hormone; Gabapentin; gamma-Aminobutyric Acid; Hormone Replacement Therapy; Hot Flashes; Humans; Menopause; Middle Aged; Mood Disorders; Randomized Controlled Trials as Topic; Sleep Wake Disorders | 2003 |
Alternatives to estrogen.
Topics: Acetates; Acupuncture Therapy; Adrenergic alpha-Agonists; Amines; Antidepressive Agents, Second-Generation; Antioxidants; Behavior Therapy; Belladonna Alkaloids; Cimicifuga; Cyclohexanecarboxylic Acids; Dietary Supplements; Drug Combinations; Ergotamines; Estrogen Replacement Therapy; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Isoflavones; Menopause; Methysergide; Phenobarbital; Phytoestrogens; Plant Preparations; Selective Serotonin Reuptake Inhibitors; Sulpiride; United States; Vitamin E; Women's Health | 2003 |
[Anticonvulsants in preventive therapy of migraine].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Migraine Disorders; Topiramate; Valproic Acid | 2003 |
Use of gabapentin for postherpetic neuralgia: results of two randomized, placebo-controlled studies.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia; Randomized Controlled Trials as Topic | 2003 |
[Nonorganic pain -- only psychogenic?].
Topics: Acetates; Adult; Amines; Analgesics; Analgesics, Opioid; Anesthetics, Local; Back Pain; Chronic Disease; Cicatrix; Complementary Therapies; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Migraine Disorders; Nociceptors; Pain; Pain Management; Physical Therapy Modalities; Procaine; Reflex Sympathetic Dystrophy; Tramadol | 2003 |
The new antiepileptic drugs: scientific review.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Tiagabine; Topiramate; Triazines; Zonisamide | 2004 |
A critical review of atypical antipsychotic utilization: comparing monotherapy with polypharmacy and augmentation.
Topics: Acetates; Amines; Anticonvulsants; Antipsychotic Agents; Clinical Trials as Topic; Clozapine; Cyclohexanecarboxylic Acids; Drug Utilization; Gabapentin; gamma-Aminobutyric Acid; Humans; Polypharmacy; Risperidone; Schizophrenia; Valproic Acid | 2004 |
Gabapentin in the treatment of neuropathic pain.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Pain Measurement; Peripheral Nervous System Diseases; Randomized Controlled Trials as Topic | 2004 |
Making sense of the evidence regarding nonhormonal treatments for hot flashes.
Topics: Acetates; Activities of Daily Living; Algorithms; Amines; Cyclohexanecarboxylic Acids; Cyclohexanols; Decision Trees; Drug Monitoring; Drug Therapy, Combination; Evidence-Based Medicine; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Middle Aged; Nursing Assessment; Patient Selection; Quality of Life; Selective Serotonin Reuptake Inhibitors; Self Care; Severity of Illness Index; Treatment Outcome; Venlafaxine Hydrochloride | 2004 |
A GABA(B) mystery: the search for pharmacologically distinct GABA(B) receptors.
Topics: Acetates; Amines; Animals; Anticonvulsants; Baclofen; Benzylamines; Cyclohexanecarboxylic Acids; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Molecular Structure; Morpholines; Phosphinic Acids; Protein Isoforms; Receptors, GABA-B; RNA, Messenger | 2001 |
Gabapentin as a drug therapy of intractable hiccup because of vascular lesion: a three-year follow up.
Topics: Acetates; Aged; Amines; Brain Stem; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Hiccup; Humans; Magnetic Resonance Imaging; Male; Stroke | 2004 |
Calcium channel alpha2delta subunits: differential expression, function, and drug binding.
Topics: Acetates; Amines; Amino Acid Sequence; Animals; Calcium Channel Blockers; Calcium Channels; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Gene Expression Regulation; Humans; Membrane Potentials; Molecular Sequence Data; Mutation; Protein Structure, Quaternary; Recombinant Proteins; Structure-Activity Relationship | 2003 |
New pharmacologic targets for the treatment of the overactive bladder: an update.
Topics: Acetates; Amines; Animals; Botulinum Toxins; Central Nervous System Agents; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; GABA Agents; Gabapentin; gamma-Aminobutyric Acid; Humans; Narcotics; Nociceptin Receptor; Receptors, Adrenergic; Receptors, Drug; Receptors, Opioid; Serotonin Antagonists; Tramadol; Urinary Incontinence | 2004 |
Diagnosis and management of neuropathic pain: a balanced approach to treatment.
Topics: Acetates; Amines; Antidepressive Agents; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Lidocaine; Narcotics; Neuralgia; Nurse Practitioners; Pain Measurement; Prevalence | 2003 |
Post-herpetic neuralgia case study: optimizing pain control.
Topics: Acetates; Aged; Amines; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Depression; Disease Management; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Herpes Zoster; Herpesvirus 3, Human; Humans; Male; Neuralgia; Pain; Quality of Life | 2004 |
Efficacy and tolerability of the new antiepileptic drugs, I: Treatment of new-onset epilepsy: report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society.
Topics: Acetates; Adolescent; Adult; Age Factors; Amines; Antipsychotic Agents; Carbamazepine; Child; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Approval; Epilepsies, Partial; Epilepsy, Absence; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Tiagabine; Topiramate; Triazines; United States; United States Food and Drug Administration; Zonisamide | 2004 |
Efficacy and tolerability of the new antiepileptic drugs, II: Treatment of refractory epilepsy: report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society.
Topics: Acetates; Adolescent; Adult; Age Factors; Amines; Anticonvulsants; Carbamazepine; Child; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Approval; Epilepsies, Partial; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Practice Patterns, Physicians'; Tiagabine; Topiramate; Triazines; United States; United States Food and Drug Administration; Zonisamide | 2004 |
Efficacy and tolerability of the new antiepileptic drugs I: treatment of new onset epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epileps
Topics: Acetates; Acute Disease; Adolescent; Adult; Amines; Anticonvulsants; Carbamazepine; Child; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Evidence-Based Medicine; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Topiramate; Treatment Outcome; Triazines | 2004 |
Efficacy and tolerability of the new antiepileptic drugs II: treatment of refractory epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epile
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Child; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Resistance; Epilepsies, Partial; Epilepsy, Generalized; Evidence-Based Medicine; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide | 2004 |
Newer anticonvulsants in the treatment of bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Depressive Disorder; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide | 2004 |
80-year-old man with fever and ear pain.
Topics: Acetates; Acyclovir; Age Factors; Aged; Aged, 80 and over; Amines; Analgesics; Antiviral Agents; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Earache; Fever; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; Oxycodone; Pain; Patient Selection; Polymerase Chain Reaction; Risk Factors; Valacyclovir; Valine | 2004 |
Gabapentin for intractable hiccup.
Topics: Acetates; Aged; Amines; Baclofen; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Guillain-Barre Syndrome; Hiccup; Humans; Male; Muscle Relaxants, Central; Tomography, X-Ray Computed | 2004 |
Antispasticity medications: uses and limitations of enteral therapy.
Topics: 4-Aminopyridine; Acetates; Adrenergic alpha-Agonists; Amines; Baclofen; Benzodiazepines; Cyclohexanecarboxylic Acids; Cyproheptadine; Dantrolene; Dronabinol; Gabapentin; gamma-Aminobutyric Acid; Glycine; Humans; Muscle Relaxants, Central; Muscle Spasticity; Neuroprotective Agents; Piracetam; Serotonin Antagonists | 2004 |
193 trial(s) available for phenyl acetate and gamma-aminobutyric acid
| Article | Year |
|---|---|
Selected CSF biochemistry and gabapentin concentrations in the CSF and plasma in patients with partial seizures after a single oral dose of gabapentin.
Topics: Acetates; Administration, Oral; Adult; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Serotonin | 1992 |
Long-term treatment with gabapentin for partial epilepsy.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Research Design; Time Factors | 1992 |
Gabapentin.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drugs, Investigational; Epilepsies, Partial; Epilepsy, Generalized; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 1991 |
Gabapentin in partial epilepsy. UK Gabapentin Study Group.
Topics: Acetates; Adolescent; Adult; Amines; Analysis of Variance; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Time Factors | 1990 |
Gabapentin as an antiepileptic drug in man.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Patient Compliance; Random Allocation | 1987 |
Evaluation of encephalotropic and psychotropic properties of gabapentin in man by pharmaco-EEG and psychometry.
Topics: Acetates; Adult; Affect; Amines; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Memory; Psychological Tests; Psychomotor Performance; Random Allocation | 1986 |
Gabapentin toxicity in children manifesting as behavioral changes.
Topics: Acetates; Affect; Aggression; Amines; Anticonvulsants; Behavior; Child; Cyclohexanecarboxylic Acids; Epilepsy, Complex Partial; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Seizures; Treatment Outcome | 1995 |
Long-term study with gabapentin in patients with drug-resistant epileptic seizures.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Placebos | 1994 |
The long-term safety and efficacy of gabapentin (Neurontin) as add-on therapy in drug-resistant partial epilepsy. The US Gabapentin Study Group.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Long-Term Care; Male; Middle Aged; Substance Withdrawal Syndrome | 1994 |
Gabapentin as add-on therapy in refractory partial epilepsy: a double-blind, placebo-controlled, parallel-group study. The US Gabapentin Study Group No. 5.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Analysis of Variance; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 1993 |
Seizure frequency and CSF parameters in a double-blind placebo controlled trial of gabapentin in patients with intractable complex partial seizures.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy, Complex Partial; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Placebo Effect; Seizures; Time Factors; Treatment Outcome | 1995 |
The effect of gabapentin on brain gamma-aminobutyric acid in patients with epilepsy.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy, Complex Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Occipital Lobe; Protons; Treatment Outcome | 1996 |
[Gabapentin (Neurontin): a new possibility in the add-on therapy of partial epilepsies].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Multicenter Studies as Topic; Randomized Controlled Trials as Topic | 1996 |
[Clinical studies on gabapentin in Switzerland].
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Male; Quality of Life; Switzerland | 1996 |
Gabapentin adjunctive therapy in neuropathic pain states.
Topics: Acetates; Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Facial Pain; Female; Gabapentin; gamma-Aminobutyric Acid; Herpesviridae Infections; HIV Infections; Humans; Intervertebral Disc Displacement; Male; Middle Aged; Neuralgia; Pain, Intractable; Peripheral Nervous System Diseases | 1996 |
Effect of gabapentin (Neurontin) [corrected] on mood and well-being in patients with epilepsy.
Topics: Acetates; Adult; Affect; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Quality of Life | 1996 |
Effect of a high-protein meal on gabapentin pharmacokinetics.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dietary Proteins; Eating; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 1996 |
Gabapentin in generalized seizures.
Topics: Acetates; Adolescent; Adult; Amines; Analysis of Variance; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Epilepsy, Generalized; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Treatment Outcome | 1996 |
Placebo-controlled trial of gabapentin in patients with amyotrophic lateral sclerosis. WALS Study Group. Western Amyotrophic Lateral Sclerosis Study Group.
Topics: Acetates; Adult; Aged; Amines; Amyotrophic Lateral Sclerosis; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 1996 |
Gabapentin in the treatment of bipolar disorder.
Topics: Acetates; Adult; Ambulatory Care; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Treatment Outcome | 1997 |
Effectiveness of gabapentin in controlling spasticity: a quantitative study.
Topics: Acetates; Adult; Amines; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Electromyography; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Movement; Muscle Spasticity; Parasympatholytics; Spinal Cord Injuries | 1997 |
Treatment of restless legs syndrome with gabapentin.
Topics: Acetates; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Restless Legs Syndrome | 1997 |
Gabapentin in naive childhood absence epilepsy: results from two double-blind, placebo-controlled, multicenter studies.
Topics: Acetates; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Monitoring; Electroencephalography; Epilepsy, Absence; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Treatment Outcome | 1996 |
Gabapentin and cognition: a double blind, dose ranging, placebo controlled study in refractory epilepsy.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Analysis of Variance; Anticonvulsants; Cognition Disorders; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuropsychological Tests | 1997 |
Gabapentin for relief of upper motor neuron symptoms in multiple sclerosis.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Cramp; Muscle Spasticity; Treatment Outcome | 1997 |
A double-blind controlled study of gabapentin and baclofen as treatment for acquired nystagmus.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Baclofen; Cyclohexanecarboxylic Acids; Double-Blind Method; Eye Movements; Female; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Nystagmus, Pathologic; Treatment Outcome; Visual Acuity | 1997 |
Gabapentin for parkinsonism: a double-blind, placebo-controlled, crossover trial.
Topics: Acetates; Adult; Aged; Amines; Antiparkinson Agents; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Electromyography; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Parkinson Disease, Secondary; Tremor | 1997 |
A pilot trial of adjunctive gabapentin in the treatment of bipolar disorder.
Topics: Acetates; Adjuvants, Pharmaceutic; Adult; Affect; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pilot Projects; Treatment Outcome | 1997 |
Gabapentin and motor fluctuations in Parkinson's disease.
Topics: Acetates; Aged; Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Motor Activity; Movement Disorders; Parkinson Disease; Treatment Outcome | 1997 |
The effect of gabapentin on neuropathic pain.
Topics: Acetates; Adolescent; Adult; Amines; Analgesics; Child; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Low Back Pain; Middle Aged; Myofascial Pain Syndromes; Pain; Peripheral Nervous System Diseases; Retrospective Studies | 1997 |
Gabapentin monotherapy: I. An 8-day, double-blind, dose-controlled, multicenter study in hospitalized patients with refractory complex partial or secondarily generalized seizures. The US Gabapentin Study Group 88/89.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Epilepsy, Complex Partial; Epilepsy, Generalized; Female; Gabapentin; gamma-Aminobutyric Acid; Hospitalization; Humans; Male; Middle Aged; Treatment Outcome | 1997 |
Gabapentin monotherapy: II. A 26-week, double-blind, dose-controlled, multicenter study of conversion from polytherapy in outpatients with refractory complex partial or secondarily generalized seizures. The US Gabapentin Study Group 82/83.
Topics: Acetates; Adolescent; Adult; Ambulatory Care; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy, Complex Partial; Epilepsy, Generalized; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Patient Dropouts; Placebos; Treatment Outcome | 1997 |
Gabapentin for the treatment of spasticity in patients with spinal cord injury.
Topics: Acetates; Administration, Oral; Adult; Amines; Anticonvulsants; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Muscle Spasticity; Paralysis; Prognosis; Prospective Studies; Reflex; Reproducibility of Results; Spinal Cord Injuries; Treatment Outcome | 1997 |
Open label gabapentin treatment for pain in multiple sclerosis.
Topics: Acetates; Adult; Aged; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multiple Sclerosis; Pain; Pain, Intractable | 1997 |
High dose gabapentin in refractory partial epilepsy: clinical observations in 50 patients.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Diarrhea; Diplopia; Dizziness; Dose-Response Relationship, Drug; Epilepsies, Myoclonic; Epilepsies, Partial; Fatigue; Female; Flatulence; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Male; Middle Aged; Seizures | 1998 |
Gabapentin: long-term antianxiety and hypnotic effects in psychiatric patients with comorbid anxiety-related disorders.
Topics: Acetates; Adult; Aged; Amines; Anti-Anxiety Agents; Anticonvulsants; Anxiety Disorders; Behavioral Symptoms; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mental Disorders; Middle Aged; Prospective Studies; Psychotropic Drugs; Treatment Outcome | 1998 |
Gabapentin absorption: effect of mixing with foods of varying macronutrient composition.
Topics: Acetates; Adult; Amines; Anticonvulsants; Area Under Curve; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Female; Food-Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 1998 |
Gabapentin does not interact with a contraceptive regimen of norethindrone acetate and ethinyl estradiol.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Contraceptives, Oral, Synthetic; Cross-Over Studies; Cyclohexanecarboxylic Acids; Drug Interactions; Estradiol Congeners; Ethinyl Estradiol; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Norethindrone | 1998 |
Conversion to high dose gabapentin monotherapy in patients with medically refractory partial epilepsy.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Epilepsies, Partial; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Medical Records; Middle Aged; Therapeutic Equivalency; Treatment Outcome | 1998 |
Oral gabapentin disposition in patients with epilepsy after a high-protein meal.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dietary Proteins; Epilepsy; Fasting; Female; Food-Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Saliva | 1997 |
Outcome evaluation of gabapentin as add-on therapy for partial seizures. "NEON" Study Investigators Group. Neurontin Evaluation of Outcomes in Neurological Practice.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neurologic Examination; Phenobarbital; Phenytoin; Primidone; Quality of Life; Valproic Acid | 1998 |
Double-blind controlled trial of gabapentin in essential tremor.
Topics: Acetates; Activities of Daily Living; Aged; Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Motor Skills; Neurologic Examination; Tremor | 1998 |
Gabapentin and carbamazepine affect eye movements and posture control differently: a placebo-controlled investigation of acute CNS side effects in healthy volunteers.
Topics: Acetates; Administration, Oral; Adult; Amines; Anticonvulsants; Carbamazepine; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Electronystagmography; Electrooculography; Eye Movements; Female; Fingers; Gabapentin; gamma-Aminobutyric Acid; Hand Strength; Humans; Isometric Contraction; Male; Middle Aged; Placebos; Posture; Prospective Studies; Saccades; Time Factors | 1998 |
Gabapentin bioavailability: effect of dose and frequency of administration in adult patients with epilepsy.
Topics: Acetates; Adult; Amines; Anticonvulsants; Biological Availability; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 1998 |
Gabapentin for treatment of pain and tremor: a large case series.
Topics: Acetates; Adult; Aged; Amines; Analgesics; Anticonvulsants; Arachnoiditis; Cerebellar Neoplasms; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; Middle Aged; Migraine Disorders; Pain; Peripheral Nervous System Diseases; Prospective Studies; Restless Legs Syndrome; Tremor; Trigeminal Neuralgia | 1998 |
Gabapentin in orthostatic tremor: results of a double-blind crossover with placebo in four patients.
Topics: Acetates; Aged; Amines; Anticonvulsants; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Electromyography; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Posture; Treatment Outcome; Tremor | 1998 |
Pharmacological control of facilitatory I-wave interaction in the human motor cortex. A paired transcranial magnetic stimulation study.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Central Nervous System Depressants; Cyclohexanecarboxylic Acids; Electric Stimulation; Ethanol; Evoked Potentials, Motor; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lorazepam; Male; Motor Cortex; Neural Inhibition; Phenobarbital; Transcranial Magnetic Stimulation; Triazines; Vigabatrin | 1998 |
Gabapentin augmentation for fluoxetine-treated patients with obsessive-compulsive disorder.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Obsessive-Compulsive Disorder; Pilot Projects; Selective Serotonin Reuptake Inhibitors; Treatment Outcome | 1998 |
Effects of gabapentin on cognition and quality of life in patients with epilepsy.
Topics: Acetates; Adult; Affect; Aged; Amines; Anticonvulsants; Cognition; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuropsychological Tests; Quality of Life; Seizures; Statistics, Nonparametric | 1998 |
Adjunctive therapy in epilepsy with new antiepileptic drugs: is it of any value?
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Clobazam; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Health Surveys; Humans; Lamotrigine; Male; Patient Compliance; Patient Satisfaction; Prospective Studies; Quality of Life; Triazines; Vigabatrin | 1998 |
Gabapentin treatment of alcohol withdrawal.
Topics: Acetates; Adult; Alcohol Withdrawal Delirium; Alcoholism; Ambulatory Care; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Ethanol; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Substance Withdrawal Syndrome; Treatment Outcome | 1998 |
Effects of gabapentin on the different components of peripheral and central neuropathic pain syndromes: a pilot study.
Topics: Acetates; Amines; Analgesics; Anticonvulsants; Central Nervous System Diseases; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuralgia; Pain Threshold; Peripheral Nervous System Diseases; Pilot Projects; Psychophysics; Stress, Mechanical; Syndrome; Touch | 1998 |
A double-blind trial of gabapentin monotherapy for newly diagnosed partial seizures. International Gabapentin Monotherapy Study Group 945-77.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Medical Records; Middle Aged; Seizures | 1998 |
Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus: a randomized controlled trial.
Topics: Acetates; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Quality of Life | 1998 |
Gabapentin for the treatment of postherpetic neuralgia: a randomized controlled trial.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Quality of Life | 1998 |
The natural history and the effects of gabapentin in amyotrophic lateral sclerosis.
Topics: Acetates; Administration, Oral; Adult; Aged; Amines; Amyotrophic Lateral Sclerosis; Cyclohexanecarboxylic Acids; Disability Evaluation; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Prognosis; Survival Analysis; Survival Rate | 1998 |
Gabapentin does not alter single-dose lithium pharmacokinetics.
Topics: Acetates; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Depression; Double-Blind Method; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium; Metabolic Clearance Rate | 1998 |
Gabapentin add-on treatment: how many patients become seizure-free? An open-label multicenter study.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Quality of Life; Seizures; Treatment Outcome | 1999 |
Cognitive effects of topiramate, gabapentin, and lamotrigine in healthy young adults.
Topics: Acetates; Adult; Affect; Amines; Anticonvulsants; Cognition Disorders; Cyclohexanecarboxylic Acids; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Neuropsychological Tests; Psychomotor Performance; Reaction Time; Single-Blind Method; Topiramate; Triazines; Word Association Tests | 1999 |
An audit of the perceived efficacy and tolerability of gabapentin therapy in an out-patient cohort with chronic epilepsy.
Topics: Acetates; Adult; Ambulatory Care; Amines; Anticonvulsants; Chronic Disease; Cohort Studies; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Medical Audit; Retrospective Studies; Treatment Outcome | 1999 |
Gabapentin in the treatment of refractory partial epilepsy in children with intellectual disability.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Retrospective Studies; Severity of Illness Index | 1998 |
Gabapentin in the treatment of painful diabetic neuropathy: a placebo controlled, double blind, crossover trial.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement | 1999 |
A randomized placebo-controlled comparative trial of gabapentin and propranolol in essential tremor.
Topics: Acetates; Administration, Oral; Aged; Amines; Antiparkinson Agents; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Propranolol; Sympatholytics; Treatment Outcome; Tremor | 1999 |
Effects of age and gender on single-dose pharmacokinetics of gabapentin.
Topics: Acetates; Administration, Oral; Adult; Age Distribution; Age Factors; Aged; Amines; Anticonvulsants; Body Constitution; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney; Kidney Function Tests; Male; Middle Aged; Regression Analysis; Sex Factors | 1999 |
Clinical experience with gabapentin in patients with bipolar or schizoaffective disorder: results of an open-label study.
Topics: Acetates; Acute Disease; Adult; Aged; Amines; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Treatment Outcome | 1999 |
Cognitive abilities and adjustment with gabapentin: results of a multisite study.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Epilepsy, Complex Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuropsychological Tests | 1999 |
Gabapentin as an adjuvant to opioid analgesia for neuropathic cancer pain.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neoplasms; Pain Measurement; Pain, Intractable | 1999 |
[Gabapentin in the treatment of mania].
Topics: Acetates; Amines; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Clozapine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales | 1999 |
Safety and tolerability of gabapentin as adjunctive therapy in a large, multicenter study.
Topics: Acetates; Adolescent; Adult; Ambulatory Care; Amines; Anticonvulsants; Asthenia; Carbamazepine; Cyclohexanecarboxylic Acids; Dizziness; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Male; Patient Dropouts; Phenytoin; Prospective Studies; Treatment Outcome; Valproic Acid | 1999 |
[Visual field defects due to antiepileptic drugs].
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Vigabatrin; Vision Disorders; Visual Field Tests; Visual Fields | 1999 |
Treatment of social phobia with gabapentin: a placebo-controlled study.
Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Personality Inventory; Phobic Disorders; Treatment Outcome | 1999 |
Low dose gabapentin for shoulder-hand syndrome induced by phenobarbital: a three-month study.
Topics: Acetates; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Phenobarbital; Reflex Sympathetic Dystrophy | 1999 |
A beneficial effect on mood in partial epilepsy patients treated with gabapentin.
Topics: Acetates; Adult; Affect; Aged; Amines; Anticonvulsants; Anxiety Disorders; Comorbidity; Cyclohexanecarboxylic Acids; Depressive Disorder; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Personality Inventory; Prospective Studies; Psychiatric Status Rating Scales; Treatment Outcome | 1999 |
Gabapentin as add-on therapy in children with refractory partial seizures: a 12-week, multicentre, double-blind, placebo-controlled study. Gabapentin Paediatric Study Group.
Topics: Acetates; Age Factors; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Placebos; Treatment Outcome | 1999 |
Treatment of alcohol withdrawal syndrome with gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Central Nervous System Depressants; Chlormethiazole; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Ethanol; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Substance Withdrawal Syndrome; Treatment Outcome | 1999 |
Gabapentin does not affect antipyrine clearance.
Topics: Acetates; Adult; Amines; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antipyrine; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Male; Phenytoin; Saliva | 1999 |
Differential cognitive effects of carbamazepine and gabapentin.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Attention; Carbamazepine; Cognition; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Electroencephalography; Evoked Potentials; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Memory; Middle Aged; Neuropsychological Tests | 1999 |
Randomized double-blind study comparing the efficacy of gabapentin with amitriptyline on diabetic peripheral neuropathy pain.
Topics: Acetates; Adrenergic Uptake Inhibitors; Aged; Amines; Amitriptyline; Analgesics; Cross-Over Studies; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Prospective Studies; Severity of Illness Index; Treatment Outcome | 1999 |
Clinical experience using adjunctive gabapentin in treatment-resistant bipolar mixed states.
Topics: Acetates; Adjuvants, Pharmaceutic; Adult; Aged; Amines; Analysis of Variance; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Drug Resistance; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Treatment Outcome | 1999 |
Lamotrigine in the treatment of bipolar depression.
Topics: Acetates; Affect; Amines; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cross-Over Studies; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Randomized Controlled Trials as Topic; Triazines | 1999 |
Monotherapy trials with gabapentin for partial epilepsy.
Topics: Acetates; Ambulatory Care; Amines; Anticonvulsants; Carbamazepine; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Hospitalization; Humans; Multicenter Studies as Topic; Placebos; Randomized Controlled Trials as Topic; Treatment Outcome | 1999 |
Dosing to efficacy with neurontin: the STEPS trial. Study of Titration to Effect Profile of Safety.
Topics: Acetates; Adult; Amines; Anticonvulsants; Clinical Trials, Phase III as Topic; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Epilepsies, Partial; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Practice Patterns, Physicians'; Product Surveillance, Postmarketing; Prospective Studies; Treatment Outcome | 1999 |
Gabapentin as adjunctive therapy for partial seizures.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dizziness; Drug Administration Schedule; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Patient Dropouts; Phenytoin; Prospective Studies; Quality of Life; Sleep Stages; Treatment Outcome | 1999 |
Postherpetic neuralgia: role of gabapentin and other treatment modalities.
Topics: Acetates; Administration, Topical; Age Factors; Aged; Ambulatory Care; Amines; Analgesics; Anticonvulsants; Antidepressive Agents, Tricyclic; Capsaicin; Carbamazepine; Clinical Trials as Topic; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; Middle Aged; Narcotics; Neuralgia; Pain; Risk Factors; Severity of Illness Index; Treatment Outcome | 1999 |
Gabapentin monotherapy for the symptomatic treatment of painful neuropathy: a multicenter, double-blind, placebo-controlled trial in patients with diabetes mellitus.
Topics: Acetates; Affect; Ambulatory Care; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Double-Blind Method; Drug Administration Schedule; Gabapentin; gamma-Aminobutyric Acid; Humans; Placebos; Quality of Life; Treatment Outcome | 1999 |
Gabapentin as an adjunct to standard mood stabilizers in outpatients with mixed bipolar symptomatology.
Topics: Acetates; Adult; Affect; Aged; Ambulatory Care; Amines; Antidepressive Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Disorders of Excessive Somnolence; Drug Therapy, Combination; Female; Follow-Up Studies; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Time Factors; Treatment Outcome | 1999 |
Gabapentin in childhood epilepsy: a prospective evaluation of efficacy and safety.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Drug Resistance; Drug Therapy, Combination; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Male; Prospective Studies | 2000 |
Gabapentin treatment for insomnia associated with alcohol dependence.
Topics: Acetates; Adult; Alcoholism; Amines; Anticonvulsants; Comorbidity; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Sleep Initiation and Maintenance Disorders; Temperance; Treatment Outcome | 2000 |
Pharmacologic reversal of cortical hyperexcitability in patients with ALS.
Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Cerebral Cortex; Cyclohexanecarboxylic Acids; Diazepam; Drug Therapy, Combination; Evoked Potentials, Motor; Female; GABA Agonists; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetics; Male; Middle Aged; Neural Inhibition; Neuroprotective Agents; Physical Stimulation; Riluzole; Synaptic Transmission; Treatment Outcome | 2000 |
Effectiveness of gabapentin for the treatment of behavioral disorders in dementia.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Anti-Anxiety Agents; Behavioral Symptoms; Cyclohexanecarboxylic Acids; Dementia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Prospective Studies; Psychomotor Agitation | 2000 |
Conversion from thrice daily to twice daily administration of gabapentin (GBP) in partial epilepsy: analysis of clinical efficacy and plasma levels.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Cross-Over Studies; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Polypharmacy; Treatment Outcome | 2000 |
Gabapentin effect on spasticity in multiple sclerosis: a placebo-controlled, randomized trial.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Cross-Over Studies; Cyclohexanecarboxylic Acids; Disability Evaluation; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Fatigue; Muscle Spasticity; Prospective Studies; Treatment Outcome | 2000 |
Gabapentin treatment for posttraumatic stress disorder.
Topics: Acetates; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Stress Disorders, Post-Traumatic | 2000 |
Effect of anticonvulsants on nocturnal sleep in epilepsy.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Circadian Rhythm; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Sleep; Triazines | 2000 |
Inter- and intra-subject variability in gabapentin absorption and absolute bioavailability.
Topics: Acetates; Adult; Amines; Analysis of Variance; Anticonvulsants; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Monitoring; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Prospective Studies | 2000 |
Treatment of chronic: new perspectives.
Topics: Acetates; Aged; Amines; Cerebral Infarction; Chronic Disease; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Hiccup; Humans; Male; Middle Aged | 1999 |
Gabapentin enhances the analgesic effect of morphine in healthy volunteers.
Topics: Acetates; Amines; Analgesia; Analgesics; Analgesics, Opioid; Area Under Curve; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Morphine; Pain Threshold | 2000 |
Gabapentin is effective in treating nocturnal painful spasms in multiple sclerosis.
Topics: Acetates; Amines; Anticonvulsants; Circadian Rhythm; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Multiple Sclerosis; Pain; Spasm; Time Factors | 2000 |
Efficacy of gabapentin as adjunctive therapy in a large, multicenter study. The Steps Study Group.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsies, Partial; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Treatment Outcome | 2000 |
Gabapentin therapy for diabetic neuropathic pain.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Treatment Outcome | 2000 |
Placebo-controlled study of gabapentin treatment of panic disorder.
Topics: Acetates; Adolescent; Adult; Aged; Agoraphobia; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Panic Disorder; Psychiatric Status Rating Scales; Sex Characteristics | 2000 |
Gabapentin for essential tremor: a multiple-dose, double-blind, placebo-controlled trial.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Antiparkinson Agents; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Essential Tremor; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neurologic Examination; Treatment Outcome | 2000 |
Gabapentin vs. amitriptyline in painful diabetic neuropathy: an open-label pilot study.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Amitriptyline; Analgesics; Ataxia; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Dizziness; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Paresthesia; Pilot Projects; Salivary Glands; Sleep Stages; Treatment Outcome | 2000 |
Gabapentin versus vigabatrin as first add-on for patients with partial seizures that failed to respond to monotherapy: a randomized, double-blind, dose titration study. GREAT Study Investigators Group. Gabapentin in Refractory Epilepsy Add-on Treatment.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Research Design; Retrospective Studies; Treatment Outcome; Vigabatrin | 2000 |
Low doses of gabapentin may be helpful in the management of chronic daily headache.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Male; Middle Aged; Patient Satisfaction; Treatment Outcome | 2000 |
A placebo-controlled study of lamotrigine and gabapentin monotherapy in refractory mood disorders.
Topics: Acetates; Adult; Amines; Antimanic Agents; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Mood Disorders; Placebos; Psychiatric Status Rating Scales; Treatment Outcome; Triazines | 2000 |
Adjunctive gabapentin treatment of bipolar disorder.
Topics: Acetates; Adult; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome | 2000 |
Increased seizures after discontinuing carbamazepine: results from the gabapentin monotherapy trial.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Seizures; Substance Withdrawal Syndrome | 2000 |
Gabapentin in the treatment of cocaine dependence: a case series.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Behavior, Addictive; Cocaine-Related Disorders; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Personality Inventory; Pilot Projects; Psychiatric Status Rating Scales; Severity of Illness Index; Substance Abuse Detection; Surveys and Questionnaires; Treatment Outcome | 2001 |
Gabapentin in bipolar disorder: a placebo-controlled trial of adjunctive therapy. Gabapentin Bipolar Disorder Study Group.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium Carbonate; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome; Valproic Acid | 2000 |
Efficacy of gabapentin in migraine prophylaxis.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Migraine Disorders | 2001 |
Topiramate as add-on treatment for patients with bipolar mania.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Body Mass Index; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium; Male; Middle Aged; Topiramate; Treatment Outcome; Valproic Acid | 1999 |
Gabapentin in the acute treatment of refractory bipolar disorder.
Topics: Acetates; Acute Disease; Adult; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Prospective Studies; Time Factors; Treatment Outcome | 1999 |
Oral gabapentin (neurontin) treatment of refractory genitourinary tract pain.
Topics: Acetates; Administration, Oral; Amines; Analgesics; Cyclohexanecarboxylic Acids; Cystitis, Interstitial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain | 2001 |
Rapid initiation of gabapentin: a randomized, controlled trial.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Double-Blind Method; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multicenter Studies as Topic; Prospective Studies; Time Factors | 2001 |
Phase III randomized trial of gabapentin in patients with amyotrophic lateral sclerosis.
Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Sample Size; Survival Analysis | 2001 |
Gabapentin as add-on therapy in children with refractory partial seizures: a 24-week, multicentre, open-label study.
Topics: Acetates; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Double-Blind Method; Epilepsy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Patient Dropouts; Treatment Failure | 2001 |
Single-dose gabapentin pharmacokinetics and safety in healthy infants and children.
Topics: Acetates; Administration, Oral; Amines; Anticonvulsants; Area Under Curve; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Infant; Male; Metabolic Clearance Rate; Regression Analysis | 2001 |
A randomized open-label study of gabapentin and lamotrigine in adults with learning disability and resistant epilepsy.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Lamotrigine; Male; Middle Aged; Severity of Illness Index; Treatment Outcome; Triazines | 2001 |
Gabapentin but not vigabatrin is effective in the treatment of acquired nystagmus in multiple sclerosis: How valid is the GABAergic hypothesis?
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; Electrooculography; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multiple Sclerosis; Nystagmus, Physiologic; Vigabatrin; Visual Acuity | 2001 |
Comparative cognitive effects of carbamazepine and gabapentin in healthy senior adults.
Topics: Acetates; Age Factors; Aged; Amines; Anticonvulsants; Attention; Carbamazepine; Cognition; Cognition Disorders; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Health Status; Humans; Incidence; Male; Middle Aged; Neuropsychological Tests | 2001 |
Myoclonus in epilepsy patients with anticonvulsive add-on therapy with pregabalin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Electroencephalography; Electromyography; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Germany; Humans; Incidence; Male; Myoclonus; Pregabalin; Randomized Controlled Trials as Topic | 2001 |
A crossover study of gabapentin in treatment of restless legs syndrome among hemodialysis patients.
Topics: Acetates; Aged; Amines; Anticonvulsants; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Renal Dialysis; Restless Legs Syndrome; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome | 2001 |
Efficacy and safety of gabapentin as an add-on therapy in refractory partial epileptic patients.
Topics: Acetates; Activities of Daily Living; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Statistics, Nonparametric; Treatment Outcome | 2001 |
Gabapentin for the treatment of patients with somatization disorder.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Measurement; Psychiatric Status Rating Scales; Somatoform Disorders; Treatment Outcome | 2001 |
Gabapentin in the treatment of hemifacial spasm.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hemifacial Spasm; Humans; Male; Middle Aged; Pilot Projects; Treatment Outcome | 2001 |
Gabapentin as a possible treatment of behavioral alterations in Alzheimer disease (AD) patients.
Topics: Acetates; Aged; Alzheimer Disease; Amines; Behavior; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Agonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 2001 |
Drug-resistant cluster headache responding to gabapentin: a pilot study.
Topics: Acetates; Adult; Amines; Analgesics; Cluster Headache; Cyclohexanecarboxylic Acids; Drug Resistance; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pilot Projects | 2001 |
A placebo-controlled trial of gabapentin in spinal muscular atrophy.
Topics: Acetates; Adult; Amines; Arm; Cyclohexanecarboxylic Acids; Double-Blind Method; Excitatory Amino Acid Antagonists; Feasibility Studies; Female; Gabapentin; gamma-Aminobutyric Acid; Hand Strength; Humans; Male; Muscle Contraction; Severity of Illness Index; Sickness Impact Profile; Spinal Muscular Atrophies of Childhood; Treatment Outcome; United States; Vital Capacity | 2001 |
Gabapentin in postherpetic neuralgia: a randomised, double blind, placebo controlled study.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Patient Satisfaction; Quality of Life; Treatment Outcome | 2001 |
Treatment of idiopathic restless legs syndrome (RLS) with gabapentin.
Topics: Acetates; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Polysomnography; Restless Legs Syndrome | 2001 |
Modification of cortical excitability induced by gabapentin: a study by transcranial magnetic stimulation.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cerebral Cortex; Cyclohexanecarboxylic Acids; Electric Stimulation; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Transcranial Magnetic Stimulation | 2001 |
Population pharmacokinetics of gabapentin in infants and children.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Body Weight; Child; Child, Preschool; Creatinine; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Metabolic Clearance Rate; Reference Values | 2001 |
Brain metabolic changes during lactate-induced panic: effects of gabapentin treatment.
Topics: Acetates; Adult; Amines; Arousal; Aspartic Acid; Brain; Cyclohexanecarboxylic Acids; Double-Blind Method; Energy Metabolism; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infusions, Intravenous; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Panic; Panic Disorder; Treatment Outcome | 2001 |
Gabapentin in PTSD: a retrospective, clinical series of adjunctive therapy.
Topics: Acetates; Adult; Aged; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Retrospective Studies; Sleep Wake Disorders; Stress Disorders, Post-Traumatic; Treatment Outcome | 2001 |
Gabapentin's effect on agitation in severely and persistently mentally ill patients.
Topics: Acetates; Amines; Antimanic Agents; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mental Disorders; Middle Aged; Mood Disorders; Pilot Projects; Psychiatric Status Rating Scales; Psychomotor Agitation; Psychotic Disorders; Retrospective Studies; Time Factors | 2002 |
Clinical predictors of response to lamotrigine and gabapentin monotherapy in refractory affective disorders.
Topics: Acetates; Adult; Aged; Amines; Antidepressive Agents; Cross-Over Studies; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Resistance; Female; Forecasting; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Mood Disorders; Recurrence; Retrospective Studies; Triazines | 2002 |
Modulation of cerebral GABA by topiramate, lamotrigine, and gabapentin in healthy adults.
Topics: Acetates; Adult; Amines; Anticonvulsants; Brain Chemistry; Cerebral Cortex; Cyclohexanecarboxylic Acids; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Topiramate; Triazines | 2002 |
The evolving role of topiramate among other mood stabilizers in the management of bipolar disorder.
Topics: Acetates; Acute Disease; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Randomized Controlled Trials as Topic; Topiramate; Triazines; Valproic Acid | 2001 |
Gabapentin attenuates superior oblique myokymia.
Topics: Acetates; Administration, Oral; Adult; Amines; Cyclohexanecarboxylic Acids; Diplopia; Excitatory Amino Acid Antagonists; Eye Movements; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Treatment Outcome; Trochlear Nerve Diseases | 2002 |
Third generation anticonvulsants in bipolar disorder: a review of efficacy and summary of clinical recommendations.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Double-Blind Method; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Placebos; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide | 2002 |
Gabapentin for relief of neuropathic pain related to anticancer treatment: a preliminary study.
Topics: Acetates; Adolescent; Amines; Analgesics; Antineoplastic Agents; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neoplasms; Pain; Pain Measurement; Palliative Care; Prospective Studies | 2002 |
Effects of gabapentin and carbamazepine on the EEG and cognition in healthy volunteers.
Topics: Acetates; Adolescent; Adult; Alpha Rhythm; Amines; Anticonvulsants; Brain; Carbamazepine; Cognition; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Electroencephalography; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuropsychological Tests; Regression Analysis | 2002 |
Gabapentin in the treatment of neuropathic pain after spinal cord injury: a prospective, randomized, double-blind, crossover trial.
Topics: Acetates; Adult; Amines; Analgesics; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Prospective Studies; Spinal Cord Injuries; Time Factors; Trauma Severity Indices; Treatment Outcome | 2002 |
[Gabapentin as therapy for vulvitis].
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Treatment Outcome; Vulvitis | 2002 |
Gabapentin versus lamotrigine monotherapy: a double-blind comparison in newly diagnosed epilepsy.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Asthenia; Clinical Protocols; Cyclohexanecarboxylic Acids; Dizziness; Double-Blind Method; Epilepsies, Partial; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Lamotrigine; Male; Middle Aged; Patient Dropouts; Proportional Hazards Models; Survival Analysis; Treatment Outcome; Triazines | 2002 |
A randomized study of the effects of single-dose gabapentin versus placebo on postoperative pain and morphine consumption after mastectomy.
Topics: Acetates; Aged; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mastectomy; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Treatment Outcome | 2002 |
Post-partum cerebral angiopathy: repetitive TCD, MRI, MRA, and EEG examinations.
Topics: Acetates; Adult; Amines; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Aspirin; Brain Edema; Cerebral Angiography; Cerebral Arteries; Cerebral Hemorrhage; Cerebrovascular Circulation; Cyclohexanecarboxylic Acids; Echoencephalography; Eclampsia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Observer Variation; Oxytocin; Postpartum Period; Pregnancy; Sensitivity and Specificity; Time Factors; Ultrasonography, Doppler, Transcranial | 2002 |
The analgesic effect of gabapentin and mexiletine after breast surgery for cancer.
Topics: Acetates; Aged; Amines; Analgesics; Analgesics, Opioid; Antineoplastic Agents; Breast Neoplasms; Chronic Disease; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mastectomy, Radical; Mexiletine; Middle Aged; Pain Measurement; Pain, Postoperative; Surveys and Questionnaires; Time Factors | 2002 |
Gabapentin and lamotrigine in Indian patients of partial epilepsy refractory to carbamazepine.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Drug Resistance; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; India; Lamotrigine; Male; Middle Aged; Triazines | 2002 |
Gabapentin in neuropathic pain syndromes: a randomised, double-blind, placebo-controlled trial.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Analysis of Variance; Chi-Square Distribution; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Quality of Life; Syndrome | 2002 |
Pilot evaluation of gabapentin for treating hot flashes.
Topics: Acetates; Adolescent; Adult; Amines; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Middle Aged; Pilot Projects; Probability; Prospective Studies; Single-Blind Method; Treatment Outcome | 2002 |
Treatment of restless legs syndrome with gabapentin: a double-blind, cross-over study.
Topics: Acetates; Adult; Aged; Amines; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Polysomnography; Random Allocation; Research Design; Restless Legs Syndrome; Sample Size; Sleep; Treatment Outcome | 2002 |
Gabapentin for the treatment of pain in guillain-barré syndrome: a double-blinded, placebo-controlled, crossover study.
Topics: Acetates; Adult; Amines; Analgesics; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Guillain-Barre Syndrome; Humans; Middle Aged; Pain | 2002 |
Gabapentin augmentation therapy in bipolar depression.
Topics: Acetates; Adult; Amines; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Clozapine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium Carbonate; Male; Pilot Projects; Prospective Studies; Severity of Illness Index; Surveys and Questionnaires | 2002 |
The absorption of gabapentin following high dose escalation.
Topics: Absorption; Acetates; Amines; Anticonvulsants; Biological Availability; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Interactions; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Saliva | 2003 |
Gabapentin in late-onset poststroke seizures.
Topics: Acetates; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Prospective Studies; Recurrence; Seizures; Stroke | 2002 |
Gabapentin's effects on hot flashes in postmenopausal women: a randomized controlled trial.
Topics: Acetates; Administration, Oral; Amines; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Middle Aged; Patient Satisfaction; Postmenopause; Probability; Quality of Life; Reference Values; Severity of Illness Index; Treatment Outcome | 2003 |
Gabapentin effect on neuropathic pain compared among patients with spinal cord injury and different durations of symptoms.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Polyradiculopathy; Sleep; Spinal Cord Injuries; Treatment Outcome | 2003 |
Characterization of gabapentin overdose using a poison center case series.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Overdose; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Male; Middle Aged; Poison Control Centers; Prospective Studies; Treatment Outcome | 2003 |
Effect of gabapentin on nausea induced by chemotherapy in patients with breast cancer.
Topics: Acetates; Administration, Oral; Amines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclohexanecarboxylic Acids; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Nausea | 2003 |
Gabapentin in antipsychotic-induced tardive dyskinesia: results of 1-year follow-up.
Topics: Acetates; Adult; Amines; Anticonvulsants; Antipsychotic Agents; Cyclohexanecarboxylic Acids; Dyskinesia, Drug-Induced; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Psychotic Disorders; Schizophrenia; Treatment Outcome | 2003 |
Effects of gabapentin on anxiety induced by simulated public speaking.
Topics: Acetates; Adolescent; Adult; Amines; Anti-Anxiety Agents; Anxiety; Blood Pressure; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Humans; Male; Speech | 2003 |
Serum concentrations and effects of gabapentin and vigabatrin: observations from a dose titration study.
Topics: Acetates; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Monitoring; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Vigabatrin | 2003 |
Open pilot study of gabapentin versus trazodone to treat insomnia in alcoholic outpatients.
Topics: Acetates; Alcoholism; Amines; Antidepressive Agents, Second-Generation; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Outpatients; Pilot Projects; Sleep Initiation and Maintenance Disorders; Sleep Stages; Trazodone | 2003 |
Use of gabapentin to reduce chronic neuropathic pain in Fabry disease.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Fabry Disease; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuralgia; Pain Measurement; Treatment Outcome | 2003 |
Role of gabapentin in spinal muscular atrophy: results of a multicenter, randomized Italian study.
Topics: Acetates; Adolescent; Adult; Amines; Arm; Child; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Isometric Contraction; Italy; Leg; Male; Middle Aged; Movement; Muscle, Skeletal; Neuroprotective Agents; Spinal Muscular Atrophies of Childhood; Treatment Outcome; Vital Capacity | 2003 |
Gabapentin versus ropinirole in the treatment of idiopathic restless legs syndrome.
Topics: Acetates; Adult; Aged; Amines; Calcium Channel Blockers; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dopamine Agonists; Drug Administration Schedule; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Indoles; Male; Middle Aged; Pilot Projects; Polysomnography; Restless Legs Syndrome; Surveys and Questionnaires | 2003 |
Treatment of acute alcohol withdrawal with gabapentin: results from a controlled two-center trial.
Topics: Acetates; Adult; Alcoholism; Amines; Analysis of Variance; Chi-Square Distribution; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Substance Withdrawal Syndrome | 2003 |
Gabapentin in the management of pentazocine dependence: a potent analgesic--anticraving agent.
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Anti-Anxiety Agents; Clonidine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain; Pentazocine; Substance Withdrawal Syndrome; Substance-Related Disorders | 2003 |
Gabapentin for the treatment of behavioural alterations in dementia: preliminary 15-month investigation.
Topics: Acetates; Aged; Amines; Anti-Anxiety Agents; Comorbidity; Cyclohexanecarboxylic Acids; Dementia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mental Disorders; Treatment Outcome | 2003 |
Gabapentin in the prophylaxis of chronic daily headache: a randomized, placebo-controlled study.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Analgesics; Anticonvulsants; Ataxia; Chronic Disease; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dizziness; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Headache Disorders; Humans; Male; Middle Aged; Pain Measurement; Quality of Life; Safety; Sleep Stages; Treatment Outcome | 2003 |
The effects of remifentanil and gabapentin on hyperalgesia in a new extended inflammatory skin pain model in healthy volunteers.
Topics: Acetates; Adult; Amines; Analgesics, Opioid; Cross-Over Studies; Cyclohexanecarboxylic Acids; Diazepam; Double-Blind Method; Drug Synergism; Excitatory Amino Acid Antagonists; Female; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Inflammation; Male; Pain Measurement; Pain Threshold; Physical Stimulation; Piperidines; Reaction Time; Remifentanil; Skin; Sunburn; Treatment Outcome | 2004 |
Gabapentin reduces cocaine use among addicts from a community clinic sample.
Topics: Acetates; Adult; Amines; Cocaine-Related Disorders; Cyclohexanecarboxylic Acids; Diagnosis, Dual (Psychiatry); Diagnostic and Statistical Manual of Mental Disorders; Excitatory Amino Acid Agonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mental Disorders; Outpatients; Substance Abuse Treatment Centers; Treatment Outcome | 2004 |
Lidocaine patch 5% with systemic analgesics such as gabapentin: a rational polypharmacy approach for the treatment of chronic pain.
Topics: Acetates; Activities of Daily Living; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Local; Chronic Disease; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Low Back Pain; Male; Middle Aged; Neuralgia; Pain; Pain Measurement; Pilot Projects; Quality of Life; Treatment Outcome | 2003 |
Gabapentin in the management of the recurrent, refractory, idiopathic priapism.
Topics: Acetates; Adult; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pilot Projects; Priapism; Recurrence; Regional Blood Flow | 2004 |
Effects of gabapentin on postoperative morphine consumption and pain after abdominal hysterectomy: a randomized, double-blind trial.
Topics: Acetates; Adult; Aged; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Dizziness; Double-Blind Method; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Hysterectomy; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Placebos; Postoperative Nausea and Vomiting; Premedication; Sleep Stages; Treatment Outcome | 2004 |
Pilot study using gabapentin for tamoxifen-induced hot flashes in women with breast cancer.
Topics: Acetates; Administration, Oral; Amines; Breast Neoplasms; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Pilot Projects; Selective Estrogen Receptor Modulators; Severity of Illness Index; Tamoxifen; Treatment Outcome | 2004 |
Gabapentin maintenance decreases smoked cocaine-related subjective effects, but not self-administration by humans.
Topics: Acetates; Adult; Amines; Blood Pressure; Choice Behavior; Cocaine; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Humans; Male; Self Administration; Smoking; Surveys and Questionnaires | 2004 |
Preemptive use of gabapentin significantly decreases postoperative pain and rescue analgesic requirements in laparoscopic cholecystectomy.
Topics: Acetates; Adult; Amines; Analgesia; Analgesics; Analgesics, Opioid; Analysis of Variance; Anesthetics, Intravenous; Cholecystectomy; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Laparoscopy; Male; Pain Measurement; Pain, Postoperative; Time Factors; Tramadol; Treatment Outcome | 2004 |
Gabapentin to control seizures in children undergoing cancer treatment.
Topics: Acetates; Amines; Anticonvulsants; Antineoplastic Agents; Brain; Child; Cyclohexanecarboxylic Acids; Electroencephalography; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neoplasms; Radiotherapy; Seizures; Severity of Illness Index | 2004 |
Gabapentin for painful legs and moving toes syndrome.
Topics: Acetates; Aged; Amines; Cyclohexanecarboxylic Acids; Electromyography; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Leg; Magnetic Resonance Imaging; Male; Movement Disorders; Pain; Syndrome; Toes | 2004 |
Analgesic effects of gabapentin after spinal surgery.
Topics: Acetates; Acute Disease; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Humans; Intervertebral Disc; Lumbar Vertebrae; Middle Aged; Morphine; Pain, Postoperative; Spinal Fusion | 2004 |
Gabapentin is a first line drug for the treatment of neuropathic pain in spinal cord injury.
Topics: Acetates; Adult; Aged; Amines; Analgesics; Cross-Over Studies; Cyclohexanecarboxylic Acids; Disability Evaluation; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Prospective Studies; Quality of Life; Sleep; Spinal Cord Injuries; Treatment Outcome | 2004 |
Add-on gabapentin in the treatment of opiate withdrawal.
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Heroin; Heroin Dependence; Humans; Male; Naltrexone; Narcotic Antagonists; Narcotics; Recurrence; Substance Withdrawal Syndrome | 2004 |
The analgesic effects of gabapentin after total abdominal hysterectomy.
Topics: Acetates; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Blood Pressure; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Humans; Hysterectomy; Middle Aged; Monitoring, Intraoperative; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Respiratory Mechanics; Tramadol | 2004 |
Use of gabapentin for attenuation of symptoms following rapid opiate detoxification (ROD)--correlation with neurophysiological parameters--.
Topics: Acetates; Adult; Amines; Anesthesia; Anesthetics, Intravenous; Cyclohexanecarboxylic Acids; Electric Stimulation; Evoked Potentials, Somatosensory; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Heroin Dependence; Hormone Antagonists; Humans; Magnesium; Male; Median Nerve; Methadone; Naltrexone; Narcotic Antagonists; Narcotics; Potassium; Propofol; Restless Legs Syndrome; Somatostatin; Substance Withdrawal Syndrome; Water-Electrolyte Balance | 2004 |
Clinical efficacy of gabapentin for paroxysmal symptoms in multiple sclerosis.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multiple Sclerosis; Peripheral Nervous System Diseases | 2004 |
Treatment of ataxia in cortical cerebellar atrophy with the GABAergic drug gabapentin. A preliminary study.
Topics: Acetates; Aged; Amines; Antiparkinson Agents; Atrophy; Cerebellar Ataxia; Cerebellar Cortex; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuropsychological Tests; Statistics, Nonparametric; Time | 2004 |
Gabapentin for neuropathic cancer pain: a randomized controlled trial from the Gabapentin Cancer Pain Study Group.
Topics: Acetates; Aged; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neoplasm Invasiveness; Nerve Compression Syndromes; Nervous System Neoplasms; Pain; Pain Measurement; Treatment Outcome | 2004 |
The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery.
Topics: Acetates; Adult; Amines; Analgesics; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Monitoring, Intraoperative; Otorhinolaryngologic Surgical Procedures; Pain Measurement; Pain, Postoperative; Paranasal Sinuses; Propofol; Rhinoplasty | 2004 |
Therapeutic outcome in neuropathic pain: relationship to evidence of nervous system lesion.
Topics: Acetates; Adult; Aged; Amines; Chi-Square Distribution; Cyclohexanecarboxylic Acids; Depression; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Imipramine; Male; Middle Aged; Pain; Pain Measurement; Sensation Disorders; Trauma, Nervous System; Treatment Outcome | 2004 |
Gabapentin for the prevention of postoperative pain after vaginal hysterectomy.
Topics: Acetates; Adult; Amines; Calcium Channel Blockers; Case-Control Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Hysterectomy, Vaginal; Male; Middle Aged; Narcotics; Oxazepam; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Time Factors | 2004 |
809 other study(ies) available for phenyl acetate and gamma-aminobutyric acid
| Article | Year |
|---|---|
Effect of amino-oxyacetic acid (AOAA) on focal penicillin seizures.
Topics: Acetates; Alanine; Aminooxyacetic Acid; Animals; Aspartic Acid; Cerebral Cortex; Disease Models, Animal; Epilepsies, Partial; gamma-Aminobutyric Acid; Glutamates; Glutamine; Ketoglutaric Acids; Penicillins; Pyruvates; Rats; Seizures; Time Factors; Transaminases | 1978 |
The effect of increased brain GABA produced by amino-oxyacetic acid on arousal in rats.
Topics: Acetates; Aminobutyrates; Aminooxyacetic Acid; Animals; Arousal; Brain Chemistry; Dopamine; Fenclonine; gamma-Aminobutyric Acid; Male; Methyltyrosines; Norepinephrine; Rats; Serotonin | 1976 |
[Classification of the responses of a giant neuron from the snail Acatina fulica Férussac, caused by inhibitory sugstances depending on chlorine ions].
Topics: Acetates; Aminobutyrates; Animals; Axons; Chlorides; gamma-Aminobutyric Acid; Snails; Structure-Activity Relationship | 1977 |
Biochemical effects in man and rat of three drugs which can increase brain GABA content.
Topics: Acetates; Adult; Amino Acids; Aminobutyrates; Aminooxyacetic Acid; Animals; Brain; gamma-Aminobutyric Acid; Humans; Huntington Disease; Isoniazid; Rats; Valerates; Valproic Acid | 1978 |
Pharmacology of Huntington's chorea. Personal experience.
Topics: Acetates; Adult; Aminobutyrates; Blood Cell Count; Bromocriptine; Female; gamma-Aminobutyric Acid; Haloperidol; Humans; Huntington Disease; Kidney Function Tests; Liver Function Tests; Male; Middle Aged; Physostigmine; Receptors, Dopamine; Valerates; Valproic Acid | 1977 |
[Effect of ammonium acetate on depolarization processes in the central terminals of primary afferents].
Topics: Acetates; Action Potentials; Animals; Cats; Electrophysiology; gamma-Aminobutyric Acid; Membrane Potentials; Neurons, Afferent; Quaternary Ammonium Compounds; Reflex, Monosynaptic; Spinal Cord; Synaptic Membranes; Synaptic Transmission | 1977 |
Compartmentation of amino acid metabolism in the rat dorsal root ganglion; a metabolic and autoradiographic study.
Topics: Acetates; Amino Acids; Animals; Autoradiography; Carbon Radioisotopes; gamma-Aminobutyric Acid; Ganglia, Spinal; Glucose; Glutamates; Glutamine; Rats; Spinal Nerve Roots | 1975 |
Factors influencing the efflux of [3H]gamma-aminobutyric acid from satellite glial cells in rat sensory ganglia.
Topics: Acetates; Aminobutyrates; Animals; Antimetabolites; Basal Ganglia; Calcium; gamma-Aminobutyric Acid; Hydroxylamines; Magnesium; Neuroglia; Potassium; Rats; Time Factors; Tritium | 1975 |
Metabolism of ethanol and acetaldehyde by the isolated perfused rat brain.
Topics: Acetaldehyde; Acetates; Animals; Aspartic Acid; Brain; Ethanol; gamma-Aminobutyric Acid; Glutamates; Glutamine; Male; Perfusion; Rats; Time Factors | 1975 |
Two forms of 4-aminobutyrate transaminase in guinea pig brain.
Topics: 4-Aminobutyrate Transaminase; Acetates; Animals; Brain; Bromides; Chlorides; Chromatography, DEAE-Cellulose; Enzyme Activation; Fluorides; gamma-Aminobutyric Acid; Guinea Pigs; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Lactates; NAD; Sodium; Time Factors; Transaminases | 1975 |
The inhibitory effect of sodium n-dipropyl acetate on the degradative enzymes of the GABA shunt.
Topics: Acetates; Aldehyde Oxidoreductases; Aminobutyrates; Animals; gamma-Aminobutyric Acid; Guinea Pigs; Kidney; Kinetics; Succinates; Transaminases | 1975 |
Effect of drugs on rat brain, cerebrospinal fluid and blood GABA content.
Topics: Acetates; Aminooxyacetic Acid; Animals; Brain; gamma-Aminobutyric Acid; Isoniazid; Kinetics; Male; Organ Specificity; Rats; Valproic Acid | 1979 |
GABA involvement in memory consolidation: evidence from posttrial amino-oxyacetic acid.
Topics: Acetates; Aminobutyrates; Aminooxyacetic Acid; Animals; Avoidance Learning; Electroshock; gamma-Aminobutyric Acid; Male; Memory; Rats; Time Factors | 1978 |
3-Mercaptopropionic acid: convulsant properties, effects on enzymes of the gamma-aminobutyrate system in mouse brain and antagonism by certain anticonvulsant drugs, aminooxyacetic acid and gabaculine.
Topics: 3-Mercaptopropionic Acid; 4-Aminobutyrate Transaminase; Acetates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Convulsants; Cyclohexanecarboxylic Acids; Cyclohexylamines; Dose-Response Relationship, Drug; Enzyme Activation; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Ketamine; Male; Mice; Sulfhydryl Compounds | 1979 |
Stability of synaptosomal GABA levels and their use in determining the in vivo effects of drugs: convulsant agents.
Topics: Acetates; Aminooxyacetic Acid; Animals; Brain; gamma-Aminobutyric Acid; Hydrazines; Isoniazid; Kinetics; Male; Mice; Seizures; Synaptosomes | 1979 |
Metabolic compartmentation of the GABA system; relationship of GABA metabolism to anesthesia.
Topics: Acetates; Acetylcholine; Anesthetics; Animals; Brain; Cerebral Cortex; Citrates; gamma-Aminobutyric Acid; Halothane; In Vitro Techniques; Kinetics; Pyruvates; Rats; Synaptosomes | 1979 |
Effect of diazepam and pentobarbital on aminooxyacetic acid-induced accumulation on GABA.
Topics: Acetates; Aminobutyrates; Aminooxyacetic Acid; Animals; Brain; Diazepam; gamma-Aminobutyric Acid; Male; Pentobarbital; Rats; Tissue Distribution | 1977 |
Studies about molluscan C.N.S.: ii) Changes induced by n-acetylaspartic acid, n-acetylaspartylglutamic acid and GABA in the activity of single identified neurones of Aplysia.
Topics: Acetates; Aminobutyrates; Animals; Aplysia; Aspartic Acid; Central Nervous System; gamma-Aminobutyric Acid; Glutamates; Mollusca | 1977 |
Aminooxyacetic acid: correlation between biochemical effects, anticonvulsant action and toxicity in mice.
Topics: 4-Aminobutyrate Transaminase; Acetates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Brain Chemistry; Chromatography, Gas; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Lethal Dose 50; Male; Mice; Time Factors | 1978 |
Cyclic GABA-GABOB analogues. II - Synthesis of new 2-oxo and 2,5-dioxo-delta3-pyrroline derivatives.
Topics: Acetates; Alkylation; Aminobutyrates; Chemical Phenomena; Chemistry; gamma-Aminobutyric Acid; Hydroxybutyrates | 1978 |
Effects of aminooxyacetic acid and L-glutamic acid-gamma-hydrazide on GABA metabolism in specific brain regions.
Topics: Acetates; Aminobutyrates; Aminooxyacetic Acid; Animals; Brain; Cerebellum; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Kinetics; Male; Organ Specificity; Rats | 1978 |
Post-mortem and aminooxyacetic acid-induced accumulation of GABA: effect of gamma-butyrolactone and picrotoxin.
Topics: 4-Butyrolactone; Acetates; Aminobutyrates; Aminooxyacetic Acid; Animals; Brain; Chloral Hydrate; Furans; gamma-Aminobutyric Acid; Male; Organ Specificity; Picrotoxin; Postmortem Changes; Rats | 1978 |
Aminooxyacetic acid induced changes in gamma-aminobutyrate metabolism at the subcellular level.
Topics: 4-Aminobutyrate Transaminase; Acetates; Aminobutyrates; Aminooxyacetic Acid; Animals; Brain; Cytosol; gamma-Aminobutyric Acid; Male; Mice; Mitochondria; Nerve Endings; Nerve Tissue Proteins; Synaptosomes; Transaminases | 1978 |
Relationship between gamma-aminobutyric acid metabolism and antivitamin B6-induced convulsions.
Topics: 4-Aminobutyrate Transaminase; Acetates; Aminooxyacetic Acid; Animals; Brain; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hydrazines; Male; Mice; Penicillamine; Pyridoxine; Seizures; Semicarbazides | 1978 |
The metabolism of GABA and other amino acids in rat substantia nigra slices following lesions of the striato-nigral pathway.
Topics: Acetates; Amino Acids; Animals; Aspartic Acid; Corpus Striatum; gamma-Aminobutyric Acid; Glutamates; Glutamine; In Vitro Techniques; Kinetics; Rats; Substantia Nigra | 1979 |
Effects of chronic treatment with amino-oxyacetic acid or sodium n-dipropylacetate on brain GABA levels and the development and regression of cobalt epileptic foci in rats.
Topics: 4-Aminobutyrate Transaminase; Acetates; Aminobutyrates; Aminooxyacetic Acid; Animals; Brain; Brain Chemistry; Cerebral Cortex; Cobalt; Electroencephalography; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male; Rats; Seizures; Time Factors; Valerates; Valproic Acid | 1976 |
Compartmentation of amino acid metabolism in small slices of rat spinal cord and cerebral cortex.
Topics: Acetates; Alanine; Amino Acids; Animals; Cerebral Cortex; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamine; Glycine; In Vitro Techniques; Rats; Spinal Cord | 1977 |
Central actions of amino-oxyacetic acid.
Topics: Acetates; Aminooxyacetic Acid; Animals; Cats; Central Nervous System; Drug Interactions; gamma-Aminobutyric Acid; Glycine; Homocysteine; Neural Inhibition; Neurons; Purkinje Cells; Spinal Cord | 1977 |
The release of amino acids synthesised from various compartmented precursors in rat spinal cord slices.
Topics: Acetates; Amino Acids; Animals; Aspartic Acid; gamma-Aminobutyric Acid; Glucose; Glutamates; In Vitro Techniques; Neuroglia; Neurons; Potassium; Protein Precursors; Protoveratrines; Rats; Spinal Cord; Tetrodotoxin | 1977 |
A dual mechanism for the anticonvulsant action of aminooxyacetic acid.
Topics: Acetates; Allyl Compounds; Aminooxyacetic Acid; Animals; Anticonvulsants; Behavior, Animal; Brain Chemistry; Electroshock; gamma-Aminobutyric Acid; Isoniazid; Male; Mice; Seizures; Time Factors | 1976 |
Elevation of brain GABA concentrations with amino-oxyacetic acid; effect on the hyperactivity syndrome produced by increased 5-hydroxytryptamine synthesis in rats.
Topics: Acetates; Aminobutyrates; Aminooxyacetic Acid; Animals; Brain; Dopamine; gamma-Aminobutyric Acid; Humans; Hyperkinesis; Male; Norepinephrine; Picrotoxin; Rats; Serotonin; Syndrome; Tranylcypromine; Tryptophan | 1976 |
Effects of aminooxyacetic acid and baclofen on the catalepsy and on the increase of mesolimbic and striatal dopamine turnover induced by haloperidol in rats.
Topics: Acetates; Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Brain Chemistry; Catalepsy; Corpus Striatum; Dopamine; Female; gamma-Aminobutyric Acid; Haloperidol; Homovanillic Acid; Humans; Limbic System; Rats; Tyrosine | 1976 |
Formation of glutamate and GABA in epileptogenic tissue from human hippocampus in vitro.
Topics: Acetates; Aminobutyrates; Epilepsy; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamine; Hippocampus; Humans; In Vitro Techniques; Neuroglia; Neurons | 1976 |
A comparative study of the utilization of glucose, acetate, glutamine and GABA as precursors of amino acids by retinal of the rat, frog, rabbit and pigeon.
Topics: Acetates; Amino Acids; Aminobutyrates; Ammonia; Animals; Aspartic Acid; Carbon Radioisotopes; Columbidae; Extracellular Space; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamine; Rabbits; Rana pipiens; Rats; Retina | 1975 |
Effect of drug-induced increase of brain GABA levels on penicillin focus.
Topics: Acetates; Action Potentials; Aminobutyrates; Aminooxyacetic Acid; Animals; Brain Chemistry; Cats; Cerebral Cortex; Electroencephalography; Female; gamma-Aminobutyric Acid; Male; Penicillins; Rats; Seizures; Valproic Acid | 1975 |
Effects of metabolic inhibitors on amino acid metabolism in rat retina: a comparison of amino-oxyacetic acid and ethanolamine-o-sulphate.
Topics: Acetates; Amino Acids; Aminooxyacetic Acid; Animals; Aspartic Acid; Ethanolamines; Female; Fluoroacetates; gamma-Aminobutyric Acid; Glutamates; Glutamine; Male; Malonates; Ouabain; Rats; Retina; Sulfuric Acids | 1975 |
Effect of x-irradiation of the biochemical maturation of rat cerebellum: metabolism of [14C]glucose and [14-C]acetate.
Topics: Acetates; Animals; Aspartic Acid; Carbon Radioisotopes; Cerebellum; gamma-Aminobutyric Acid; Glucose; Glutamine; Radiation Effects; Rats; X-Rays | 1975 |
Metabolic compartmentation in the brain: effects of a central nervous system depressant, 1-hydroxy-3-amino-pyrrolidone-2.
Topics: Acetates; Amines; Amino Acids; Animals; Aspartic Acid; Blood-Brain Barrier; Body Temperature; Brain Chemistry; Carbon Radioisotopes; Citric Acid Cycle; gamma-Aminobutyric Acid; Glucose; Glutamates; Male; Mice; Motor Activity; Pyrrolidinones; Tritium | 1975 |
Compartmentation of amino acid metabolism in the rat posterior pituitary.
Topics: Acetates; Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Radioisotopes; Dansyl Compounds; gamma-Aminobutyric Acid; Glucose; Glutamates; Glycine; Pituitary Gland, Posterior; Rats; Serine; Taurine; Tritium | 1975 |
Substance P and spinal neurones.
Topics: Acetates; Acetylcholine; Animals; Cats; Decerebrate State; Depression, Chemical; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Interneurons; Iontophoresis; Microelectrodes; Motor Neurons; Neural Conduction; Physical Stimulation; Radioimmunoassay; Rats; Sodium Glutamate; Spinal Cord; Stimulation, Chemical; Substance P; Time Factors | 1975 |
Computer simulation of the metabolism of guinea pig brain slices, and how they differ from the intact brain.
Topics: Acetates; Aminobutyrates; Animals; Aspartic Acid; Brain; Carbon Radioisotopes; Citric Acid Cycle; Computers; gamma-Aminobutyric Acid; Glutamates; Glutamine; Guinea Pigs; Ketoglutaric Acids; Models, Biological; Succinates | 1975 |
The formation of glutamine in mouse brain: effect of amino-oxyacetic acid and ammonia.
Topics: Acetates; Aminooxyacetic Acid; Ammonium Chloride; Animals; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamine; Mice | 1975 |
Effects of amino-oxyacetic acid, ethanolamine-O-sulphate and GABA on the contents of GABA and various amines in brain slices.
Topics: Acetates; Aminobutyrates; Aminooxyacetic Acid; Animals; Biogenic Amines; Brain Chemistry; Dopamine; Ethanolamines; gamma-Aminobutyric Acid; Hypothalamus; Mesencephalon; Norepinephrine; Rats; Serotonin | 1975 |
[Antagonistic effect of sodium hydroxybutyrate on several effects of aminoxyacetic acid].
Topics: Acetates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; gamma-Aminobutyric Acid; Hydroxybutyrates; Mice; Seizures; Semicarbazides; Sodium Oxybate | 1975 |
Anticonvulsant activity of aminooxyacetic acid on convulsions induced by thiosemicarbazide.
Topics: Acetates; Aminobutyrates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; gamma-Aminobutyric Acid; Male; Mice; Seizures; Semicarbazides | 1976 |
Electrically induced release of (3H)GABA from neocortical thin slices. Effects of stimulus waveform and of amino-oxyacetic acid.
Topics: Acetates; Aminobutyrates; Aminoisobutyric Acids; Aminooxyacetic Acid; Animals; Biological Transport; Cerebral Cortex; Electric Conductivity; Electric Stimulation; gamma-Aminobutyric Acid; In Vitro Techniques; Rats | 1976 |
GABAergic and cholinergic mediation in the antinociceptive action of homotaurine.
Topics: Acetates; Acetic Acid; Analgesics; Animals; Baclofen; gamma-Aminobutyric Acid; Immersion; Male; Mice; Pain; Pain Measurement; Parasympathetic Nervous System; Reaction Time; Scopolamine; Taurine | 1992 |
Selective inhibition of glial cell metabolism in vivo by fluorocitrate.
Topics: Acetates; Animals; Aspartic Acid; Carbon Radioisotopes; Citrates; Corpus Striatum; gamma-Aminobutyric Acid; Glutamates; Glutamine; Ketoglutaric Acids; Male; Neuroglia; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains; Reference Values; Stereotaxic Techniques | 1992 |
Stability studies of gabapentin in aqueous solutions.
Topics: Acetates; Amines; Anticonvulsants; Buffers; Cyclohexanecarboxylic Acids; Drug Stability; Gabapentin; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Kinetics; Molecular Structure; Osmolar Concentration; Solutions; Temperature; Water | 1992 |
Postsynaptic fall in intracellular pH and increase in surface pH caused by efflux of formate and acetate anions through GABA-gated channels in crayfish muscle fibres.
Topics: Acetates; Animals; Astacoidea; Formates; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Channels; Muscles | 1990 |
Alpha 2u-globulin nephropathy without nephrocarcinogenesis in male Wistar rats administered 1-(aminomethyl)cyclohexaneacetic acid.
Topics: Acetates; Alpha-Globulins; Amines; Animals; Chromatography, Gel; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Glomerulonephritis; Immunohistochemistry; Kidney Diseases; Kidney Neoplasms; Kidney Tubules, Proximal; Male; Organ Size; Rats; Rats, Inbred Strains | 1991 |
Comparison of gabapentin with other antiepileptic and GABAergic drugs.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Carbamazepine; Cats; Cyclohexanecarboxylic Acids; Electric Stimulation; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Injections, Intravenous; Maxillary Nerve; Phenytoin; Reaction Time; Trigeminal Nuclei | 1991 |
Gabapentin increases aminooxyacetic acid-induced GABA accumulation in several regions of rat brain.
Topics: Acetates; Amines; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain Chemistry; Cyclohexanecarboxylic Acids; Electroshock; Female; Gabapentin; gamma-Aminobutyric Acid; Rats; Rats, Inbred Strains; Seizures | 1991 |
Cerebral metabolism of acetate and glucose studied by 13C-n.m.r. spectroscopy. A technique for investigating metabolic compartmentation in the brain.
Topics: Acetates; Acetic Acid; Amino Acids; Animals; Brain; Carbon Isotopes; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Glutamine; Guinea Pigs; Kinetics; Magnetic Resonance Spectroscopy; Male | 1990 |
Cerebral metabolism of [1,2-13C2]acetate as detected by in vivo and in vitro 13C NMR.
Topics: Acetates; Amino Acids; Animals; Brain; Carbon Isotopes; Citric Acid Cycle; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Inositol; Isotope Labeling; Magnetic Resonance Spectroscopy; Male; Models, Biological; Rats; Rats, Inbred Strains | 1990 |
Intestinal absorption of gabapentin in rats.
Topics: Acetates; Amines; Animals; Biological Transport, Active; Cyclohexanecarboxylic Acids; Diffusion; Female; Gabapentin; gamma-Aminobutyric Acid; Intestinal Absorption; Rats | 1991 |
Lack of a pharmacokinetic interaction between phenobarbitone and gabapentin.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Phenobarbital | 1991 |
Determination of gabapentin in plasma and urine by capillary column gas chromatography.
Topics: Acetates; Amines; Chromatography, Gas; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans | 1990 |
Aspartate aminotransferase for synthesis of transmitter glutamate in the medulla oblongata: effect of aminooxyacetic acid and 2-oxoglutarate.
Topics: Acetates; Amino Acids; Aminooxyacetic Acid; Animals; Aspartate Aminotransferases; beta-Alanine; Electric Stimulation; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ketoglutaric Acids; Male; Medulla Oblongata; Neurotransmitter Agents; Rats; Rats, Inbred Strains | 1989 |
Mechanisms of action of new antiepileptic drugs.
Topics: Acetamides; Acetates; Amines; Aminocaproates; Aminopyridines; Anti-Anxiety Agents; Anticonvulsants; Aspartic Acid; Benzodiazepines; Benzodiazepinones; Clobazam; Cyclohexanecarboxylic Acids; Dibenzocycloheptenes; Dizocilpine Maleate; Epilepsy; Felbamate; Flumazenil; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Imidazoles; Lamotrigine; Phenylcarbamates; Propylene Glycols; Receptors, GABA-A; Triazines; Vigabatrin | 1989 |
Nuclear magnetic resonance study of regional metabolism after forebrain ischemia in rats.
Topics: Acetates; Amino Acids; Animals; Brain; Cerebrovascular Circulation; gamma-Aminobutyric Acid; Ischemic Attack, Transient; Lactates; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Inbred Strains | 1989 |
Effect of ferric nitrilotriacetate on predominantly cortical neuronal cell cultures.
Topics: Acetates; Animals; Benzodiazepinones; Binding, Competitive; Cerebral Cortex; Choline O-Acetyltransferase; Clonazepam; Ferric Compounds; Flunitrazepam; gamma-Aminobutyric Acid; Mice; Neurons; Nitrilotriacetic Acid; Proteins | 1989 |
Use of inhibitors of gamma-aminobutyric acid (GABA) transaminase for the estimation of GABA turnover in various brain regions of rats: a reevaluation of aminooxyacetic acid.
Topics: 4-Aminobutyrate Transaminase; Acetates; Aminooxyacetic Acid; Animals; Brain; Diazepam; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Kinetics; Organ Specificity; Rats; Rats, Inbred Strains; Reference Values | 1989 |
Effects of ammonium salts on synaptic transmission to hippocampal CA1 and CA3 pyramidal cells in vivo.
Topics: Acetates; Action Potentials; Ammonium Chloride; Animals; Aspartic Acid; Drug Interactions; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Male; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Synaptic Transmission | 1985 |
[Selected inhibition of aminooxyacetic acid on a high-affinity GABA uptake system in mouse brain homogenates].
Topics: 4-Aminobutyrate Transaminase; Acetates; Aminooxyacetic Acid; Animals; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; gamma-Aminobutyric Acid; Hypothalamus; Mice | 1986 |
The picrotoxinin binding site and its relationship to the GABA receptor complex.
Topics: Acetates; Acetic Acid; Animals; Brain; Chlorides; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Picrotoxin; Rats; Receptors, GABA-A; Sesterterpenes; Sodium | 1985 |
Comparative pharmacological effects on visual cortical neurons in monocularly deprived cats.
Topics: Acetates; Amblyopia; Ammonium Chloride; Animals; Bicuculline; Cats; gamma-Aminobutyric Acid; Naloxone; Neural Inhibition; Synaptic Transmission; Visual Cortex | 1985 |
Development of tolerance to the anticonvulsant effect of GABAmimetic drugs in genetically epilepsy-prone gerbils.
Topics: Acetates; Alkynes; Aminocaproates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Diazepam; Drug Tolerance; Epilepsy; Female; gamma-Aminobutyric Acid; Gerbillinae; Isoxazoles; Male; Oxazoles; Valproic Acid | 1986 |
Gabapentin augments whole blood serotonin in healthy young men.
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Melatonin; Reference Values; Serotonin; Sleep; Sleep, REM | 1988 |
Effect of aminooxyacetic acid on the release of preloaded [3H]GABA and radioactive metabolites from slices of developing mouse brain.
Topics: Acetates; Aging; Aminooxyacetic Acid; Animals; Brain; gamma-Aminobutyric Acid; In Vitro Techniques; Mice | 1988 |
Potentiation of the anticonflict effects of diazepam, but not pentobarbital and phenobarbital, by aminooxyacetic acid (AOAA).
Topics: Acetates; Aminooxyacetic Acid; Animals; Anxiety; Behavior, Animal; Conflict, Psychological; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Female; gamma-Aminobutyric Acid; Pentobarbital; Phenobarbital; Rats; Rats, Inbred Strains | 1988 |
[GABA synthesis in the central nervous system of rats with extrapyramidal syndrome after acute cobalt acetate poisoning in cerebral ischemia].
Topics: Acetates; Acetic Acid; Acute Disease; Animals; Basal Ganglia Diseases; Brain; gamma-Aminobutyric Acid; Male; Rats; Rats, Inbred Strains | 1987 |
Effect of GABAergic drugs in the behavioral 'despair' test in rats.
Topics: Acetates; Aminooxyacetic Acid; Animals; Baclofen; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Isoxazoles; Male; Motor Activity; Muscimol; Oxazoles; Picrotoxin; Rats | 1986 |
Pharmacokinetics and metabolism of gabapentin in rat, dog and man.
Topics: Acetates; Adult; Amines; Animals; Biotransformation; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Dogs; Erythrocytes; Feces; Female; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Kinetics; Male; Protein Binding; Rats; Rats, Inbred Strains; Species Specificity; Tissue Distribution | 1986 |
GABAergic drugs can enhance or attenuate chlordiazepoxide-induced sleep time in a heterogeneous strain of mice.
Topics: Acetates; Aminooxyacetic Acid; Animals; Bicuculline; Chlordiazepoxide; GABA Antagonists; gamma-Aminobutyric Acid; Mice; Pentylenetetrazole; Picrotoxin; Sleep | 1986 |
Effect of aminooxyacetic acid on gamma-aminobutyric acid release from frog retina.
Topics: Acetates; Aminooxyacetic Acid; Animals; gamma-Aminobutyric Acid; In Vitro Techniques; Potassium; Rana temporaria; Retina | 1985 |
In vivo effects of aminooxyacetic acid and valproic acid on nerve terminal (synaptosomal) GABA levels in discrete brain areas of the rat. Correlation to pharmacological activities.
Topics: Acetates; Aminooxyacetic Acid; Animals; Brain Chemistry; Female; gamma-Aminobutyric Acid; Nerve Endings; Rats; Rats, Inbred Strains; Synaptosomes; Valproic Acid | 1985 |
Determination of gabapentin in plasma and urine by high-performance liquid chromatography and pre-column labelling for ultraviolet detection.
Topics: Acetates; Amines; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Kinetics; Microchemistry; Spectrophotometry, Ultraviolet; Trinitrobenzenesulfonic Acid | 1985 |
Gabapentin decreases monoamine release without affecting acetylcholine release in the brain.
Topics: Acetates; Acetylcholine; Amines; Animals; Caudate Nucleus; Cerebral Cortex; Cyclohexanecarboxylic Acids; Electric Stimulation; Female; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Norepinephrine; Rabbits; Rats; Rats, Inbred Strains; Serotonin | 1985 |
Gamma-aminobutyric acid: drug-induced elevation in monkey brain.
Topics: Acetates; Aminobutyrates; Animals; Brain; Carbon Radioisotopes; Carboxy-Lyases; gamma-Aminobutyric Acid; Glutamates; Haplorhini; Humans; Huntington Disease; Hydroxylamines; Isoniazid; Ketoglutaric Acids; Male; Pyridoxal Phosphate; Species Specificity; Time Factors; Transaminases | 1974 |
Release of (3H)gamma-aminobutyric acid from glial cells in rat dorsal root ganglia.
Topics: Acetates; Alanine; Aminobutyrates; Animals; Calcium; Carbon Radioisotopes; gamma-Aminobutyric Acid; Ganglia, Spinal; Glutamates; Glycine; Hydroxylamines; Kinetics; L-Lactate Dehydrogenase; Lanthanum; Leucine; Magnesium; Neuroglia; Osmolar Concentration; Phenytoin; Potassium; Rats; Time Factors; Tritium | 1974 |
Evidence for the compartmentation of glutamate metabolism in isolated rat retina.
Topics: Acetates; Animals; Aspartic Acid; Bicarbonates; Carbon Radioisotopes; Chromatography, Paper; Female; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamine; Hydroxylamines; Leucine; Male; Ouabain; Rats; Retina; Serine; Time Factors | 1974 |
A comparison of the effects of GABA and imidazoleacetic acid on the membrane conductance of lobster muscle fibres.
Topics: Acetates; Aminobutyrates; Animals; Cell Membrane; Dose-Response Relationship, Drug; Drug Interactions; Electric Conductivity; gamma-Aminobutyric Acid; Imidazoles; Muscles; Nephropidae; Picrotoxin; Receptors, Drug; Stimulation, Chemical | 1974 |
Properties of brain L-glutamate decarboxylase: inhibition studies.
Topics: Acetates; Amino Acids; Animals; Anions; Benzoates; Binding, Competitive; Brain; Carbon Radioisotopes; Carboxy-Lyases; Carboxylic Acids; Cations, Divalent; Cations, Monovalent; Chloromercuribenzoates; Dioxanes; Disulfides; Ethanol; gamma-Aminobutyric Acid; Glutamates; Hydroxylamines; Iodoacetates; Kinetics; Mercaptoethanol; Mice; Nitro Compounds; Norepinephrine; Ribonucleotides; Serotonin; Sulfhydryl Compounds; Sulfhydryl Reagents | 1974 |
Glutamate metabolism in the frog retina.
Topics: Acetates; Animals; Aspartic Acid; Autoradiography; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamine; Rana temporaria; Retina; Tritium | 1974 |
Dissociation between amino-oxyacetic acid-induced depression of spinal reflexes and the rise in cord GABA levels.
Topics: Acetates; Aminobutyrates; Animals; Carotid Arteries; Cats; Conditioning, Psychological; Decerebrate State; Depression, Chemical; Dose-Response Relationship, Drug; Evoked Potentials; Extremities; gamma-Aminobutyric Acid; Hydroxylamines; Ligation; Reflex; Semicarbazides; Spine; Synapses | 1974 |
[The relation between the crystalline structure and biological activity of molecules of the di- and tripropyl acetates].
Topics: Acetamides; Acetanilides; Acetates; Animals; Anticonvulsants; Brain; Cattle; Crystallization; gamma-Aminobutyric Acid; Kinetics; Molecular Conformation; Spectrophotometry, Ultraviolet; Transaminases; X-Ray Diffraction | 1974 |
Proceedings: Pharmacological studies on single neurones in the substantia nigra of the rat.
Topics: Acetates; Acetylcholine; Animals; Electric Stimulation; Female; gamma-Aminobutyric Acid; Glycine; Imidazoles; Iontophoresis; Neurons; Norepinephrine; Picrotoxin; Rats; Serotonin; Strychnine; Substantia Nigra | 1974 |
The effect of diazepam on spinal cord activities: possible sites and mechanisms of action.
Topics: Acetates; Alkaloids; Animals; Anthracenes; Binding Sites; Cats; Chlorpromazine; Decerebrate State; Diazepam; Dioxoles; Drug Interactions; Electric Stimulation; Gallamine Triethiodide; gamma-Aminobutyric Acid; Hindlimb; Isoquinolines; Muscles; Reflex; Reflex, Monosynaptic; Skin; Solvents; Spinal Cord; Spinal Nerve Roots; Thiosemicarbazones; Time Factors | 1974 |
[Metabolism of glutamate and related amino acids in the brain].
Topics: Acetates; Alanine; Alanine Transaminase; Amino Acids; Animals; Aspartate Aminotransferases; Aspartic Acid; Brain; Brain Chemistry; Carbon Radioisotopes; Dinitrophenols; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glycine; Hypoxia, Brain; Keto Acids; Ketoglutaric Acids; Lactates; Pyruvates | 1973 |
Subunit structure and kinetic properties of 4-aminobutyrate-2-ketoglutarate transaminase purified from mouse brain.
Topics: Acetates; Animals; Brain; Cations, Divalent; Chloromercuribenzoates; Dioxanes; Electrophoresis, Polyacrylamide Gel; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Hydroxylamines; Ketoglutaric Acids; Kinetics; Mercury; Mice; Molecular Weight; Propionates; Spectrophotometry; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Transaminases | 1974 |
L-glutamic acid decarboxylase in non-neural tissues of the mouse.
Topics: Acetates; Amino Acids; Animals; Brain; Brain Chemistry; Carbon Radioisotopes; Carboxy-Lyases; gamma-Aminobutyric Acid; Glutamates; Hydroxylamines; Kidney; Liver; Methods; Mice; Organ Specificity; Pancreas; Polyethylene Glycols; Pyruvates; Spleen | 1974 |
Drug-induced changes in GABA content of nerve endings in 11 rat brain regions. Correlation to pharmacological effects.
Topics: Acetates; Aminooxyacetic Acid; Animals; Brain; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Rats; Rats, Inbred Strains; Seizures; Synaptic Transmission; Synaptosomes; Valproic Acid | 1984 |
Alteration in neuronal-glial metabolism of glutamate by the neurotoxin kainic acid.
Topics: Acetates; Animals; Cerebellum; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Glutamine; Kainic Acid; Male; Neuroglia; Pyrrolidines; Rats; Tetrodotoxin; Veratridine | 1982 |
The release and neosynthesis of glutamic acid are increased in experimental models of hepatic encephalopathy.
Topics: Acetates; Animals; Cerebral Cortex; Disease Models, Animal; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Hepatic Encephalopathy; Male; Rats; Rats, Inbred Strains | 1983 |
Hypothalamic tyrosine hydroxylase activity, plasma gonadotropin and prolactin levels after aminooxyacetic acid in ovariectomized rats.
Topics: Acetates; Aminooxyacetic Acid; Animals; Castration; Female; Follicle Stimulating Hormone; gamma-Aminobutyric Acid; Gonadotropins, Pituitary; Hypothalamus; Luteinizing Hormone; Prolactin; Rats; Rats, Inbred Strains; Tyrosine 3-Monooxygenase | 1984 |
Effect of acute and chronic ethanol treatment on gamma-aminobutyric acid levels and on aminooxyacetic acid-induced GABA accumulation.
Topics: Acetates; Alcoholism; Aminooxyacetic Acid; Animals; Brain Chemistry; Caudate Nucleus; Cerebellum; Cerebral Cortex; Ethanol; gamma-Aminobutyric Acid; Humans; Male; Rats; Synaptic Transmission | 1980 |
Pharmacological studies on sympathoinhibition produced by the medial medullary depressor region: proposed gamma-aminobutyric acid involvement in inhibition of somatosympathetic reflexes.
Topics: Acetates; Aminooxyacetic Acid; Animals; Bicuculline; Cats; Evoked Potentials; gamma-Aminobutyric Acid; Medulla Oblongata; Pressoreceptors; Receptors, Cell Surface; Receptors, GABA-A; Reflex; Semicarbazides; Sympathetic Nervous System | 1982 |
Aminooxyacetic acid induced accumulation of GABA in the rat brain. Interaction with GABA receptors and distribution in compartments.
Topics: 3-Mercaptopropionic Acid; Acetates; Aminooxyacetic Acid; Animals; Bicuculline; Brain; Cell Compartmentation; Cell Fractionation; Cerebellum; Drug Interactions; Female; gamma-Aminobutyric Acid; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Seizures; Synaptosomes | 1983 |
The effect of excess K+ on two different tricarboxylate cycles in rat brain cortex slices.
Topics: Acetates; Adenosine Triphosphate; Amino Acids; Animals; Aspartic Acid; Carbon Dioxide; Cerebral Cortex; Citric Acid Cycle; Female; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamine; In Vitro Techniques; Male; Oxygen Consumption; Potassium; Rats | 1980 |
Influence of aminooxyacetic acid on the potassium-evoked release of [3H]gamma-aminobutyric acid from slices of rat cerebral cortex.
Topics: 4-Aminobutyrate Transaminase; Acetates; Aminooxyacetic Acid; Animals; Calcium; Cerebral Cortex; Chromatography, Ion Exchange; gamma-Aminobutyric Acid; In Vitro Techniques; Potassium; Rats; Tritium | 1984 |
Aminooxyacetic acid provides transient protection against seizures induced by hyperbaric oxygen.
Topics: Acetates; Aminooxyacetic Acid; Animals; Anticonvulsants; Atmospheric Pressure; Brain Chemistry; Chickens; gamma-Aminobutyric Acid; Male; Oxygen; Seizures; Time Factors | 1983 |
Inhibition by GABA, baclofen and gabapentin of dopamine release from rabbit caudate nucleus: are there common or different sites of action?
Topics: Acetates; Amines; Animals; Baclofen; Bicuculline; Binding Sites; Caudate Nucleus; Cyclohexanecarboxylic Acids; Dopamine; Female; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Nipecotic Acids; Rabbits | 1983 |
Interactions of di-n-propylacetate, gabaculine, and aminooxyacetic acid: anticonvulsant activity and the gamma-aminobutyrate system.
Topics: Acetates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; gamma-Aminobutyric Acid; Kinetics; Mice; Valproic Acid | 1981 |
The influence of isolation and aminooxyacetic acid (AOAA) on GABA in muricidal rats.
Topics: Acetates; Aggression; Aminooxyacetic Acid; Amygdala; Animals; Brain; gamma-Aminobutyric Acid; Humans; Hypothalamus; Limbic System; Male; Muridae; Olfactory Bulb; Social Isolation | 1982 |
Effects of aminooxyacetic acid on in vivo gamma-aminobutyric acid system of rat oviduct.
Topics: 4-Aminobutyrate Transaminase; Acetates; Aminooxyacetic Acid; Animals; Brain Chemistry; Fallopian Tubes; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Rats; Rats, Inbred Strains | 1983 |
The use of inhibitors of GABA-transaminase for the determination of GABA turnover in mouse brain regions: an evaluation of aminooxyacetic acid and gabaculine.
Topics: 4-Aminobutyrate Transaminase; Acetates; Aminooxyacetic Acid; Animals; Brain; Cyclohexanecarboxylic Acids; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Mice; Time Factors; Transaminases | 1982 |
GABA turnover in mouse brain: agreement between the rate of GABA accumulation after aminooxyacetic acid and the rate of disappearance after 3-mercaptopropionic acid.
Topics: 3-Mercaptopropionic Acid; Acetates; Aminooxyacetic Acid; Animals; Brain; Brain Chemistry; Female; gamma-Aminobutyric Acid; Male; Mice; Postmortem Changes; Sulfhydryl Compounds; Time Factors | 1982 |
Current concepts: II. Effect of aminooxyacetic acid and bicuculline on prolactin release in castrated male rats.
Topics: Acetates; Aminooxyacetic Acid; Animals; Bicuculline; Castration; gamma-Aminobutyric Acid; Male; Prolactin; Rats; Sulpiride | 1980 |
Effect of aminooxyacetic acid on endogenous GABA release from rat retina.
Topics: Acetates; Amino Acids; Aminooxyacetic Acid; Animals; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Potassium; Rats; Retina | 1981 |
Concomitant increases in serum growth hormone and hypothalamic somatostatin in rats after injection of gamma-aminobutyric acid, aminooxyacetic acid, or gamma-hydroxybutyric acid.
Topics: Acetates; Aminooxyacetic Acid; Animals; gamma-Aminobutyric Acid; Growth Hormone; Hydroxybutyrates; Hypothalamus; Levodopa; Male; Rats; Somatostatin | 1980 |
Inhibition of kindling-induced generalized seizures by aminooxyacetic acid.
Topics: Acetates; Aminooxyacetic Acid; Amygdala; Animals; Anticonvulsants; Electric Stimulation; Electroencephalography; gamma-Aminobutyric Acid; Male; Rats; Seizures | 1980 |
Histofluorescence studies of the effect of AOAA and etomidate on catecholamine terminals. Possible GABA-NA interaction in the cerebellar cortex.
Topics: Acetates; Aminooxyacetic Acid; Animals; Caudate Nucleus; Cerebellar Cortex; Etomidate; gamma-Aminobutyric Acid; Imidazoles; Male; Microscopy, Fluorescence; Norepinephrine; Putamen; Rats; Receptors, Adrenergic; Receptors, Dopamine | 1980 |
Effect of aminooxyacetic acid (AOAA) on GABA levels in some parts of the rat brain.
Topics: 3-Mercaptopropionic Acid; 4-Aminobutyrate Transaminase; Acetates; Aminooxyacetic Acid; Animals; Brain Chemistry; Cerebellum; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male; Medulla Oblongata; Pons; Rats | 1980 |
On the importance of GABA-ergic neurons for the AOAA induced accumulation of GABA in the rat brain.
Topics: Acetates; Aminooxyacetic Acid; Animals; Brain; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Male; Neurons; Rats | 1980 |
The gamma-aminobutyrate content of nerve endings (synaptosomes) in mice after the intramuscular injection of gamma-aminobutyrate-elevating agents: a possible role in anticonvulsant activity.
Topics: Acetates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Cyclohexylamines; Cycloserine; gamma-Aminobutyric Acid; Hydrazines; Kinetics; Male; Mice; Synaptosomes | 1980 |
Gabapentin actions on ligand- and voltage-gated responses in cultured rodent neurons.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Calcium Channels; Cells, Cultured; Cerebral Cortex; Cyclohexanecarboxylic Acids; Fetus; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ion Channel Gating; Ion Channels; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Neurons, Afferent; Nodose Ganglion; Rats; Sodium Channels; Spinal Cord; Synapses | 1993 |
Determination of gabapentin in serum by capillary electrophoresis.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Electrophoresis, Capillary; Gabapentin; gamma-Aminobutyric Acid; Humans; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1995 |
Disposition of gabapentin (neurontin) in mice, rats, dogs, and monkeys.
Topics: Acetates; Administration, Oral; Amines; Animals; Anticonvulsants; Autoradiography; Biological Availability; Biotransformation; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Dogs; Female; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Injections, Intravenous; Macaca fascicularis; Male; Mice; Protein Binding; Rats; Rats, Sprague-Dawley; Species Specificity; Tissue Distribution | 1995 |
Gabapentin in the management of reflex sympathetic dystrophy.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Reflex Sympathetic Dystrophy | 1995 |
The role of newer anticonvulsants in the management of epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Australia; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Vigabatrin | 1995 |
New drugs for the treatment of epilepsy.
Topics: Acetates; Amines; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines | 1995 |
Hypomania induced by gabapentin.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy, Complex Partial; Epilepsy, Tonic-Clonic; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 1995 |
Optimized method for determination of gabapentin in serum by high-performance liquid chromatography.
Topics: Acetates; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrogen-Ion Concentration | 1995 |
Gabapentin--a new antiepileptic drug.
Topics: Acetates; Aged; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Seizures | 1994 |
Reduction of GABA-mediated inhibitory postsynaptic potentials in hippocampal CA1 pyramidal neurons following oral flurazepam administration.
Topics: Acetates; Acetic Acid; Anesthetics, Local; Animals; Depression, Chemical; Electric Stimulation; Electrophysiology; Evoked Potentials; Flurazepam; GABA Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Lidocaine; Male; Organophosphorus Compounds; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Sodium Channels; Synapses | 1995 |
Gabapentin for behavioral dyscontrol.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mental Disorders | 1995 |
Disposition of gabapentin in anuric subjects on hemodialysis.
Topics: Acetates; Administration, Oral; Adolescent; Adult; Aged; Amines; Anticonvulsants; Anuria; Cyclohexanecarboxylic Acids; Dialysis Solutions; Female; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; Renal Dialysis | 1995 |
Transport of gabapentin, a gamma-amino acid drug, by system l alpha-amino acid transporters: a comparative study in astrocytes, synaptosomes, and CHO cells.
Topics: Acetates; Amines; Amino Acid Transport Systems; Amino Acids; Animals; Arginine; Astrocytes; Binding, Competitive; Biological Transport; Carrier Proteins; CHO Cells; Cricetinae; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Kinetics; Leucine; Male; Rats; Rats, Sprague-Dawley; Synaptosomes | 1995 |
Gabapentin (NEURONTIN)--a novel anticonvulsant.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 1994 |
Pancreatic acinar cell neoplasia in male Wistar rats following 2 years of gabapentin exposure.
Topics: Acetates; Adenoma; Amines; Animals; Anticonvulsants; Carcinoma, Acinar Cell; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Male; Pancreatic Neoplasms; Rats; Rats, Wistar; Sex Factors; Time Factors | 1995 |
Gabapentin treatment of seizures in acute intermittent porphyria.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Porphyria, Acute Intermittent | 1995 |
Neurontin--1 year on. London October 1994.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Approval; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Product Surveillance, Postmarketing; Treatment Outcome; United Kingdom; United States | 1995 |
Gabapentin potentiates the conductance increase induced by nipecotic acid in CA1 pyramidal neurons in vitro.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Synergism; Electric Conductivity; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Nipecotic Acids; Patch-Clamp Techniques; Proline; Pyramidal Cells; Rats; Rats, Wistar | 1995 |
Adult-onset hypothyroidism and the cerebral metabolism of (1,2-13C2) acetate as detected by 13C nuclear magnetic resonance.
Topics: Acetates; Age of Onset; Animals; Brain; Brain Chemistry; Carbon Isotopes; Electronic Data Processing; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hypothyroidism; Magnetic Resonance Spectroscopy; Models, Neurological; Rats; Rats, Wistar; Thyroidectomy; Thyroxine; Tissue Extracts | 1995 |
Successful treatment of reflex sympathetic dystrophy with gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Reflex Sympathetic Dystrophy; Treatment Outcome | 1995 |
New antiepileptic medications.
Topics: 4-Aminobutyrate Transaminase; Acetamides; Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Tiagabine; Triazines; Vigabatrin | 1995 |
Developmental toxicity studies in mice, rats, and rabbits with the anticonvulsant gabapentin.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Embryonic and Fetal Development; Female; Gabapentin; gamma-Aminobutyric Acid; Intubation, Gastrointestinal; Litter Size; Male; Mice; Mice, Inbred Strains; Rabbits; Rats; Rats, Inbred Strains | 1994 |
Absence of Ki-ras mutations in exocrine pancreatic tumors from male rats chronically exposed to gabapentin.
Topics: Acetates; Adenocarcinoma; Adenoma; Amines; Animals; Base Sequence; Codon; Cyclohexanecarboxylic Acids; DNA, Neoplasm; Gabapentin; gamma-Aminobutyric Acid; Genes, ras; Hyperplasia; Male; Molecular Sequence Data; Pancreas; Pancreatic Neoplasms; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Proteins p21(ras); Rats; Rats, Wistar | 1995 |
Successful treatment of seizures and porphyria with gabapentin.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Porphyria Cutanea Tarda; Seizures | 1995 |
Interaction of gabapentin with other antiepileptics.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Phenytoin | 1994 |
Gabapentin as add-on therapy for refractory partial epilepsy: results of five placebo-controlled trials.
Topics: Acetates; Amines; Anticonvulsants; Clinical Trials as Topic; Confidence Intervals; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Drugs, Investigational; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Multicenter Studies as Topic; Placebos | 1994 |
Gabapentin increases GABA-induced depolarization in rat neonatal optic nerve.
Topics: Acetates; Action Potentials; Amines; Animals; Animals, Newborn; Anticonvulsants; Bicuculline; Cyclohexanecarboxylic Acids; GABA-A Receptor Antagonists; Gabapentin; gamma-Aminobutyric Acid; Membrane Potentials; Neuromuscular Depolarizing Agents; Nipecotic Acids; Optic Nerve; Proline; Rats; Rats, Wistar; Receptors, GABA-A | 1994 |
FDA approved new drug bulletin. Gabapentin (neurontin).
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Patient Education as Topic; Pregnancy; United States; United States Food and Drug Administration | 1994 |
Pharmacokinetics of gabapentin in subjects with various degrees of renal function.
Topics: Acetates; Administration, Oral; Adolescent; Adult; Aged; Amines; Creatinine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Diseases; Male; Middle Aged; Renal Insufficiency | 1994 |
Direct demonstration by [13C]NMR spectroscopy that glutamine from astrocytes is a precursor for GABA synthesis in neurons.
Topics: Acetates; Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Glucose; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Glutamine; Magnetic Resonance Spectroscopy; Methionine Sulfoximine; Mice; Neurons | 1993 |
Glycerol 3-phosphate and lactate as indicators of the cerebral cytoplasmic redox state in severe and mild hypoxia respectively: a 13C- and 31P-n.m.r. study.
Topics: Acetates; Adenosine Triphosphate; Alanine; Cerebral Cortex; Cytoplasm; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycerophosphates; Hypoxia, Brain; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; NAD; Oxidation-Reduction; Phosphocreatine | 1993 |
Novel antiepileptic drugs: nursing implications.
Topics: Acetates; Amines; Aminocaproates; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Approval; Drug Interactions; Drug Monitoring; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Patient Care Planning; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin | 1993 |
Gabapentin anticonvulsant action in rats: disequilibrium with peak drug concentrations in plasma and brain microdialysate.
Topics: Acetates; Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Microdialysis; Rats; Rats, Sprague-Dawley | 1993 |
Gabapentin--a new anticonvulsant.
Topics: Acetates; Amines; Animals; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 1994 |
Limitation by gabapentin of high frequency action potential firing by mouse central neurons in cell culture.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Cells, Cultured; Cerebral Cortex; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Membrane Potentials; Mice; Neurons; Refractory Period, Electrophysiological; Spinal Cord | 1994 |
Lack of serious toxicity following gabapentin overdose.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Overdose; Female; Gabapentin; gamma-Aminobutyric Acid; Humans | 1994 |
Science reporters hear wide range of recent data at 12th annual conference.
Topics: Acetates; Aged; AIDS Vaccines; American Medical Association; Amines; Animals; Anticonvulsants; beta-Cyclodextrins; Cells, Cultured; Clinical Trials as Topic; Cochlear Implants; Complementary Therapies; Constriction, Pathologic; Coronary Artery Bypass; Cyclodextrins; Cyclohexanecarboxylic Acids; Depressive Disorder; Drug Therapy, Combination; Epilepsy; Extracorporeal Membrane Oxygenation; Felbamate; Fetus; Gabapentin; gamma-Aminobutyric Acid; Genetic Therapy; Health Care Costs; HIV Infections; Humans; Hyperlipoproteinemia Type II; Lamotrigine; Muscle, Smooth; National Institutes of Health (U.S.); Oxygen; Phenylcarbamates; Propylene Glycols; Respiration, Artificial; Respiratory Distress Syndrome; Triazines; United States; Vascular Surgical Procedures | 1993 |
[3H]gabapentin may label a system-L-like neutral amino acid carrier in brain.
Topics: Acetates; Amines; Amino Acids; Animals; Binding, Competitive; Brain Chemistry; Carrier Proteins; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Mice; Protein Binding; Swine; Synaptic Membranes | 1993 |
Potent and stereospecific anticonvulsant activity of 3-isobutyl GABA relates to in vitro binding at a novel site labeled by tritiated gabapentin.
Topics: Acetates; Amines; Animals; Anticonvulsants; Binding, Competitive; Cerebral Cortex; Cyclohexanecarboxylic Acids; Electroshock; Gabapentin; gamma-Aminobutyric Acid; Injections, Intravenous; Male; Mice; Pregabalin; Receptors, GABA-A; Stereoisomerism; Synaptic Membranes | 1993 |
Characterisation of [3H]gabapentin binding to a novel site in rat brain: homogenate binding studies.
Topics: Acetates; Amines; Amino Acids; Animals; Anticonvulsants; Baclofen; Binding Sites; Cell Membrane; Cerebral Cortex; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Rats; Receptors, GABA-A; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spermidine; Spermine | 1993 |
Localization of [3H]gabapentin to a novel site in rat brain: autoradiographic studies.
Topics: Acetates; Amines; Animals; Anticonvulsants; Autoradiography; Binding Sites; Brain; Cerebral Cortex; Corpus Striatum; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Male; Quinolinic Acid; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1993 |
Effects of gabapentin on release of gamma-aminobutyric acid from slices of rat neostriatum.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Neostriatum; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A | 1993 |
A saturable transport mechanism in the intestinal absorption of gabapentin is the underlying cause of the lack of proportionality between increasing dose and drug levels in plasma.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glycine; Humans; In Vitro Techniques; Intestinal Absorption; Leucine; Male; Perfusion; Permeability; Phenylalanine; Rats; Rats, Wistar | 1993 |
New antiepileptic medications.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Electroencephalography; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines | 1995 |
The anticonvulsant gabapentin enhances promoted release of GABA in hippocampus: a field potential analysis.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Electrophysiology; Extracellular Space; Female; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; Microinjections; Nipecotic Acids; Proline; Pyramidal Cells; Rats; Rats, Wistar | 1995 |
Costing of antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Argentina; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Costs; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Triazines; Vigabatrin | 1996 |
Effects of anticonvulsant drug gabapentin on the enzymes in metabolic pathways of glutamate and GABA.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Cytosol; Gabapentin; gamma-Aminobutyric Acid; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; In Vitro Techniques; Kinetics; Male; Mitochondria; Rats; Rats, Sprague-Dawley; Synaptosomes; Transaminases | 1995 |
Potential treatment of amyotrophic lateral sclerosis with gabapentin: a hypothesis.
Topics: Acetates; Amines; Amino Acids, Branched-Chain; Amyotrophic Lateral Sclerosis; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Humans | 1995 |
[Gabapentin--a new add-on antiepileptic drug].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 1996 |
[Current role of novel antiepileptics in the treatment of epilepsies].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Resistance; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Triazines; Vigabatrin | 1996 |
[Recommendations on clinical epilepsy treatment using gabapentin].
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Child; Contraindications; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 1996 |
Image directed proton spectroscopy of gerbil brain at 7 tesla.
Topics: Acetates; Amino Acids; Animals; Aspartic Acid; Brain; Choline; Creatine; gamma-Aminobutyric Acid; Gerbillinae; Glucose; Hydrogen; Magnetic Resonance Spectroscopy; Male; Software | 1995 |
Behavioral side effects of gabapentin in children.
Topics: Acetates; Aggression; Akathisia, Drug-Induced; Amines; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Child, Preschool; Comorbidity; Cyclohexanecarboxylic Acids; Developmental Disabilities; Dose-Response Relationship, Drug; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 1996 |
Restless legs syndrome.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Restless Legs Syndrome | 1996 |
Gabapentin associated with aggressive behavior in pediatric patients with seizures.
Topics: Acetates; Adolescent; Age Factors; Aggression; Amines; Anticonvulsants; Child; Child Behavior Disorders; Cyclohexanecarboxylic Acids; Epilepsy, Complex Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Male; Seizures | 1996 |
Choreoathetotic movements: A possible side effect of gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Athetosis; Chorea; Cyclohexanecarboxylic Acids; Dyskinesia, Drug-Induced; Epilepsies, Partial; Facial Muscles; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Movement | 1996 |
Exacerbation of seizures in Lennox-Gastaut syndrome by gabapentin.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Male; Syndrome | 1996 |
The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channel.
Topics: Acetates; Amines; Animals; Anticonvulsants; Calcium Channels; Cell Line; Cell Membrane; Cerebral Cortex; Chlorocebus aethiops; Chromatography; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Cyclohexanecarboxylic Acids; DNA, Complementary; Durapatite; Electrophoresis, Polyacrylamide Gel; Gabapentin; gamma-Aminobutyric Acid; Kinetics; Macromolecular Substances; Molecular Weight; Muscle, Skeletal; Rabbits; Recombinant Proteins; Swine; Transfection; Tritium | 1996 |
Epilepsy in porphyria.
Topics: 5-Aminolevulinate Synthetase; Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease-Free Survival; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Heme; Humans; Liver; Male; Porphyrias; Porphyrias, Hepatic | 1996 |
Postpoliomyelitis pain treated with gabapentin.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pain; Postpoliomyelitis Syndrome | 1996 |
Efficacy of gabapentin therapy in children with refractory partial seizures.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Child; Child Behavior; Child, Preschool; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Male; Treatment Outcome | 1996 |
Antimyoclonic effect of gabapentin in a posthypoxic animal model of myoclonus.
Topics: Acetates; Acoustic Stimulation; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; DDT; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Hypoxia; Male; Myoclonus; Rats; Rats, Sprague-Dawley; Seizures | 1996 |
[New medical treatment of epilepsy].
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Costs; Epilepsy; France; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Middle Aged; Triazines; Vigabatrin | 1996 |
The simultaneous estimation of the influx and efflux blood-brain barrier permeabilities of gabapentin using a microdialysis-pharmacokinetic approach.
Topics: Acetates; Amines; Animals; Anticonvulsants; Blood-Brain Barrier; Brain; Brain Chemistry; Cyclohexanecarboxylic Acids; Dialysis; Gabapentin; gamma-Aminobutyric Acid; Male; Permeability; Rats; Rats, Sprague-Dawley; Reproducibility of Results | 1996 |
Gabapentin, valproic acid, and ethanol intoxication: elevated blood levels with mild clinical effects.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Overdose; Ethanol; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Seizures; Suicide, Attempted; Valproic Acid | 1996 |
Management of restless legs syndrome with gabapentin (Neurontin)
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Restless Legs Syndrome; Treatment Outcome | 1996 |
Add-on gabapentin for refractory seizures in patients with brain tumours.
Topics: Acetates; Amines; Anticonvulsants; Brain Neoplasms; Cyclohexanecarboxylic Acids; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Seizures | 1996 |
Reduction of fasciculations in patients with amyotrophic lateral sclerosis with the use of gabapentin.
Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Anticonvulsants; Cyclohexanecarboxylic Acids; Fasciculation; Gabapentin; gamma-Aminobutyric Acid; Humans | 1996 |
Comparison of the uptake of [3H]-gabapentin with the uptake of L-[3H]-leucine into rat brain synaptosomes.
Topics: Acetates; Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Leucine; Rats; Synaptosomes; Temperature; Time Factors | 1996 |
Comparison of the autoradiographic binding distribution of [3H]-gabapentin with excitatory amino acid receptor and amino acid uptake site distributions in rat brain.
Topics: Acetates; Amines; Amino Acids; Animals; Anticonvulsants; Autoradiography; Binding, Competitive; Brain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Rats; Receptors, Amino Acid; Tissue Distribution | 1996 |
Gabapentin for the treatment of hemifacial spasm.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Facial Nerve Diseases; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Spasm | 1996 |
Gabapentin as a novel treatment for postherpetic neuralgia.
Topics: Acetates; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia | 1996 |
An audit of the new antiepileptic drugs in clinical neurological practice.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Treatment Outcome; Triazines; Vigabatrin | 1996 |
Effects of antiepileptic drugs on motor cortex excitability in humans: a transcranial magnetic stimulation study.
Topics: 4-Aminobutyrate Transaminase; Acetates; Adult; Amines; Anticonvulsants; Baclofen; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Differential Threshold; Enzyme Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Motor Cortex; Physical Stimulation; Transcranial Magnetic Stimulation; Vigabatrin | 1996 |
Determination of gabapentin in plasma by high-performance liquid chromatography.
Topics: Acetates; Amines; Amino Acids; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Quality Control; Sensitivity and Specificity | 1996 |
Movement disorders associated with the use of gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Benzodiazepines; Cyclohexanecarboxylic Acids; Dyskinesia, Drug-Induced; Dystonia; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lorazepam; Male; Myoclonus; Ocular Motility Disorders | 1996 |
Hypomania induced by gabapentin.
Topics: Acetates; Affect; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Electroencephalography; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Learning Disabilities | 1995 |
Weight gain and gabapentin therapy.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Weight Gain | 1995 |
Gabapentin interaction with felbamate.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Phenylcarbamates; Propylene Glycols | 1996 |
Portacaval anastomosis results in altered neuron--astrocytic metabolic trafficking of amino acids: evidence from 13C-NMR studies.
Topics: Acetates; Amino Acids; Animals; Astrocytes; Carbon Isotopes; Carboxylic Acids; Citric Acid Cycle; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Magnetic Resonance Spectroscopy; Male; Models, Biological; Neurons; Portacaval Shunt, Surgical; Rats; Rats, Sprague-Dawley; Reference Values | 1996 |
Metabolic precursors and compartmentation of cerebral GABA in vigabatrin-treated rats.
Topics: 4-Aminobutyrate Transaminase; Acetates; Amino Acids; Animals; Brain; Carbon Isotopes; Enzyme Inhibitors; gamma-Aminobutyric Acid; Glucose; Glutamine; Hydrogen; Magnetic Resonance Spectroscopy; Male; Models, Neurological; Organ Specificity; Rats; Rats, Wistar; Vigabatrin | 1996 |
The antiepileptic agent gabapentin (Neurontin) possesses anxiolytic-like and antinociceptive actions that are reversed by D-serine.
Topics: Acetates; Amines; Analgesics; Animals; Anti-Anxiety Agents; Callithrix; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Pain Measurement; Rats; Rats, Wistar; Serine | 1996 |
Determination of gabapentin in serum using solid-phase extraction and gas-liquid chromatography.
Topics: Acetamides; Acetates; Amines; Anticonvulsants; Calibration; Chromatography, Gas; Cycloheptanes; Cyclohexanecarboxylic Acids; Flame Ionization; Fluoroacetates; Gabapentin; gamma-Aminobutyric Acid; Humans; Organosilicon Compounds; Reference Standards; Reproducibility of Results; Silanes; Trifluoroacetic Acid | 1996 |
Long-term consequences of subtle stimuli during the first twenty-four hours of seizure-induced brain injury.
Topics: Acetates; Amines; Animals; Anticonvulsants; Appetitive Behavior; Brain Damage, Chronic; Cholinergic Fibers; Cyclohexanecarboxylic Acids; Dominance, Cerebral; Electromagnetic Fields; Gabapentin; gamma-Aminobutyric Acid; Limbic System; Lithium; Male; Maze Learning; Mental Recall; Pilocarpine; Prednisolone; Rats; Seizures | 1996 |
If comparisons can be odious, so can assumptions.
Topics: Acetates; Amines; Anticonvulsants; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Quality of Life; Treatment Outcome; Triazines; Vigabatrin | 1996 |
Hemodialysis and hemoperfusion for treatment of valproic acid and gabapentin poisoning.
Topics: Acetates; Adult; Amines; Anticonvulsants; Biomarkers; Blood Chemical Analysis; Chromatography, Thin Layer; Coma; Cyclohexanecarboxylic Acids; GABA Agents; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Hemoperfusion; Humans; Hypotension; Intensive Care Units; Male; Renal Dialysis; Shock; Valproic Acid | 1996 |
Gabapentin.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 1996 |
Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis.
Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Animals; Brain; Cyclohexanecarboxylic Acids; Diet; Disease Progression; Gabapentin; gamma-Aminobutyric Acid; Humans; Mice; Mice, Transgenic; Oxidative Stress; Riluzole; Spinal Cord; Superoxide Dismutase; Survival Analysis; Thiazoles; Vitamin E | 1996 |
The anticonvulsant gabapentin decreases firing rates of substantia nigra pars reticulata neurons.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Rats; Rats, Wistar; Substantia Nigra | 1996 |
Gabapentin for behavioral agitation in Alzheimer's disease.
Topics: Acetates; Aged; Alzheimer Disease; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Haloperidol; Humans; Psychomotor Agitation; Treatment Outcome | 1997 |
Reflex sympathetic dystrophy treated with gabapentin.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pain Measurement; Reflex Sympathetic Dystrophy | 1997 |
Treatment of acute mania with gabapentin.
Topics: Acetates; Acute Disease; Adult; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Psychiatric Status Rating Scales | 1997 |
Colonic absorption of antiepileptic agents.
Topics: Acetates; Amines; Animals; Anticonvulsants; Biological Transport; Chromatography, High Pressure Liquid; Colon; Cyclohexanecarboxylic Acids; Dogs; Drug Overdose; Gabapentin; gamma-Aminobutyric Acid; Instillation, Drug; Intestinal Absorption; Intestine, Small; Phenytoin | 1997 |
Stuttering caused by gabapentin.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Seizures; Stuttering | 1997 |
New treatment options for epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines | 1997 |
New antiepileptic drugs: case studies.
Topics: Acetates; Amines; Anticonvulsants; Child, Preschool; Cyclohexanecarboxylic Acids; Drug Resistance; Electroencephalography; Epilepsies, Partial; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Male; Topiramate; Triazines | 1997 |
Erythromelalgia pain managed with gabapentin.
Topics: Acetates; Adult; Amines; Analgesics; Child; Cyclohexanecarboxylic Acids; Erythromelalgia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain | 1997 |
Gabapentin, ineffective in normal rats, markedly reduces C-fibre evoked responses after inflammation.
Topics: Acetates; Afferent Pathways; Amines; Analgesics; Animals; Carrageenan; Cyclohexanecarboxylic Acids; Electric Stimulation; Evoked Potentials; Gabapentin; gamma-Aminobutyric Acid; Inflammation; Male; Nerve Fibers; Rats; Rats, Sprague-Dawley; Reference Values; Spinal Cord | 1997 |
Utility of the lethargic (lh/lh) mouse model of absence seizures in predicting the effects of lamotrigine, vigabatrin, tiagabine, gabapentin, and topiramate against human absence seizures.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Evaluation, Preclinical; Electroencephalography; Epilepsy, Absence; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Mice; Nipecotic Acids; Tiagabine; Topiramate; Triazines; Vigabatrin | 1997 |
Spinal gabapentin is antinociceptive in the rat formalin test.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley | 1997 |
Spermine modulation of specific [3H]-gabapentin binding to the detergent-solubilized porcine cerebral cortex alpha 2 delta calcium channel subunit.
Topics: Acetates; Amines; Animals; Anticonvulsants; Calcium Channels; Cations, Divalent; Cerebral Cortex; Chromatography, Gel; Cyclohexanecarboxylic Acids; Detergents; Dialysis; Gabapentin; gamma-Aminobutyric Acid; Membrane Proteins; Polysorbates; Protein Binding; Radioligand Assay; Spermine; Swine; Tritium | 1997 |
Gabapentin in bipolar disorder.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Retrospective Studies | 1997 |
The effect of novel anti-epileptic drugs in rat experimental models of acute and chronic pain.
Topics: Acetates; Acute Disease; Amines; Analgesics; Animals; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electroshock; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Lamotrigine; Male; Pain; Phenylcarbamates; Propylene Glycols; Rats; Rats, Sprague-Dawley; Triazines | 1997 |
Gabapentin for idiopathic trigeminal neuralgia: report of two cases.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Retreatment; Trigeminal Neuralgia | 1997 |
Incontinence during treatment with gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy; Fecal Incontinence; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Urinary Incontinence | 1997 |
A naturalistic study of the use of vigabatrin, lamotrigine and gabapentin in adults with learning disabilities.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Comorbidity; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Lamotrigine; Learning Disabilities; Male; Middle Aged; Retrospective Studies; Seizures; Social Behavior Disorders; Substance-Related Disorders; Treatment Outcome; Triazines; Vigabatrin | 1997 |
[Gabapentine--advances in the management of epilepsy].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 1994 |
Psychomotor agitation following gabapentin use in brain injury.
Topics: Acetates; Adult; Akathisia, Drug-Induced; Amines; Analgesics; Brain Injuries; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuralgia; Phantom Limb | 1997 |
[Gabapentin--a new anti-epileptic agent].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 1994 |
Amelioration of refractory dysesthetic limb pain in multiple sclerosis by gabapentin.
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Multiple Sclerosis; Pain | 1997 |
Choreoathetosis as a side effect of gabapentin therapy in severely neurologically impaired patients.
Topics: Acetates; Adult; Amines; Anticonvulsants; Athetosis; Chorea; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Male | 1997 |
Neurochemical actions of gabapentin in mouse brain.
Topics: Acetates; Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice; Mice, Inbred ICR | 1997 |
Effects of felbamate, gabapentin and lamotrigine on seizure parameters and excitability in the rat hippocampus.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Evoked Potentials; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Lamotrigine; Male; Phenylcarbamates; Propylene Glycols; Rats; Rats, Sprague-Dawley; Seizures; Triazines | 1997 |
Comparison of the preclinical anticonvulsant profiles of tiagabine, lamotrigine, gabapentin and vigabatrin.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Lamotrigine; Male; Mice; Nipecotic Acids; Rats; Rats, Sprague-Dawley; Tiagabine; Triazines; Vigabatrin | 1997 |
Changes in body weight with chronic, high-dose gabapentin therapy.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Body Weight; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Time Factors; Weight Gain; Weight Loss | 1997 |
Contrasting nutrient effects on the plasma levels of an amino acid-like antiepileptic agent from jejunal administration in dogs.
Topics: Acetates; Amines; Animals; Anticonvulsants; Area Under Curve; Cyclohexanecarboxylic Acids; Diet; Dogs; Female; Food-Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Intestinal Absorption; Jejunum; Male; Rats; Rats, Sprague-Dawley | 1997 |
Gabapentin (neurontin) and S-(+)-3-isobutylgaba represent a novel class of selective antihyperalgesic agents.
Topics: Acetates; Amines; Analgesics; Animals; Calcium Channel Blockers; Calcium Channels; Cyclohexanecarboxylic Acids; Discrimination Learning; Drug Tolerance; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Motility; Hyperalgesia; Male; Morphine; Naloxone; Pregabalin; Rats; Rats, Sprague-Dawley; Stereoisomerism | 1997 |
Gabapentin enhances the antinociceptive effects of spinal morphine in the rat tail-flick test.
Topics: Acetates; Amines; Analgesics; Animals; Bicuculline; Cyclohexanecarboxylic Acids; Drug Combinations; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Morphine; Movement; Naloxone; Narcotic Antagonists; Nociceptors; Pain Measurement; Rats; Rats, Sprague-Dawley; Tail | 1997 |
Gabapentin abuse in a cocaine user: implications for treatment?
Topics: Acetates; Adult; Amines; Anticonvulsants; Crack Cocaine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Self Medication; Stress Disorders, Post-Traumatic; Substance Withdrawal Syndrome; Substance-Related Disorders | 1997 |
Evaluation of gabapentin and S-(+)-3-isobutylgaba in a rat model of postoperative pain.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Morphine; Pain, Postoperative; Pregabalin; Rats; Rats, Sprague-Dawley | 1997 |
Alopecia associated with gabapentin: first case.
Topics: Acetates; Adolescent; Alopecia; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans | 1997 |
alpha2u-Globulin nephropathy and ravens: do ravens of a different feather flock together?
Topics: Acetates; Alpha-Globulins; Amines; Animals; Anticonvulsants; Carcinogenicity Tests; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney; Kidney Neoplasms; Rats; Reproducibility of Results | 1997 |
Acute treatment of bipolar depression with gabapentin.
Topics: Acetates; Acute Disease; Adult; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 1997 |
Gabapentin for familial paroxysmal dystonic choreoathetosis.
Topics: Acetates; Amines; Antiparkinson Agents; Athetosis; Child, Preschool; Chorea; Cyclohexanecarboxylic Acids; Dystonia; Electroencephalography; Family Health; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Videotape Recording | 1997 |
Pain in Guillain-Barré syndrome.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Polyradiculoneuropathy | 1997 |
[Trials with gabapentin monotherapy in patients with complex partial or secondary generalized seizures].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Electroencephalography; Epilepsies, Partial; Epilepsy, Complex Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Randomized Controlled Trials as Topic; Research Design; Treatment Outcome | 1997 |
Use of gabapentin in a case of facial neuritis.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Facial Neuralgia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Neuritis | 1997 |
Modulation of excitatory amino acids pathway: a possible therapeutic approach to chronic daily headache associated with analgesic drugs abuse.
Topics: Acetates; Adult; Amines; Chronic Disease; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Lamotrigine; Male; Middle Aged; Migraine Disorders; Opioid-Related Disorders; Substance Withdrawal Syndrome; Triazines | 1997 |
The novel anticonvulsant, gabapentin, protects against both convulsant and anxiogenic aspects of the ethanol withdrawal syndrome.
Topics: Acetates; Amines; Animals; Anticonvulsants; Ataxia; Behavior, Animal; Cyclohexanecarboxylic Acids; Ethanol; Gabapentin; gamma-Aminobutyric Acid; Male; Maze Learning; Mice; Motor Activity; Seizures; Substance Withdrawal Syndrome | 1997 |
Gabapentin reverses the allodynia produced by the administration of anti-GD2 ganglioside, an immunotherapeutic drug.
Topics: Acetates; Amines; Analgesics; Animals; Antibodies, Monoclonal; Blood Pressure; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Gangliosides; Male; Pain; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine | 1998 |
[GabapentinE++--improved treatment possibility for epilepsy].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 1994 |
Characterization of the effects of gabapentin and 3-isobutyl-gamma-aminobutyric acid on substance P-induced thermal hyperalgesia.
Topics: Acetates; Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Glutamate; Serine; Stereoisomerism; Substance P | 1998 |
Isolation of the [3H]gabapentin-binding protein/alpha 2 delta Ca2+ channel subunit from porcine brain: development of a radioligand binding assay for alpha 2 delta subunits using [3H]leucine.
Topics: Acetates; Amines; Animals; Calcium Channels; Cerebral Cortex; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Kinetics; Leucine; Macromolecular Substances; Neurons; Protein Binding; Radioligand Assay; Swine; Tritium | 1998 |
The effect of intrathecal gabapentin and 3-isobutyl gamma-aminobutyric acid on the hyperalgesia observed after thermal injury in the rat.
Topics: Acetates; Amines; Animals; Anticonvulsants; Burns; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Spinal; Male; Pain; Pregabalin; Rats; Rats, Sprague-Dawley; Reflex; Serine; Stereoisomerism; Structure-Activity Relationship | 1998 |
HIV neuropathy treated with gabapentin.
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; HIV Infections; Humans; Male; Middle Aged; Peripheral Nervous System Diseases | 1998 |
Overdose with gabapentin and lamotrigine.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Overdose; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines | 1997 |
Comparison of the effects of drugs on hyperexcitability induced in hippocampal slices by withdrawal from chronic ethanol consumption.
Topics: Acetates; Alcoholism; Amines; Animals; Behavior, Animal; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Diltiazem; Ethanol; Felodipine; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Isradipine; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Substance Withdrawal Syndrome | 1998 |
Sensitive high-performance liquid chromatographic method with fluorometric detection for the simultaneous determination of gabapentin and vigabatrin in serum and urine.
Topics: Acetates; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Sensitivity and Specificity; Spectrometry, Fluorescence; Vigabatrin | 1998 |
Gabapentin induced polyneuropathy.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Polyneuropathies | 1998 |
Isolated ataxia as an idiosyncratic side-effect under gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cerebellar Ataxia; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electroencephalography; Epilepsies, Partial; Epilepsy, Complex Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neurologic Examination | 1997 |
Rebound psychiatric and physical symptoms after gabapentin discontinuation.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Obsessive-Compulsive Disorder; Recurrence; Substance Withdrawal Syndrome | 1998 |
[Gabapentin--a new antiepileptic agent].
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Retrospective Studies | 1998 |
Gabapentin add-on therapy with adaptable dosages in 610 patients with partial epilepsy: an open, observational study. The French Gabapentin Collaborative Group.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Treatment Outcome; Vigabatrin | 1998 |
Gabapentin for lancinating neuropathic pain.
Topics: Acetates; Acquired Immunodeficiency Syndrome; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neoplasms; Pain; Peripheral Nervous System Diseases; Reflex Sympathetic Dystrophy | 1998 |
Alternative uses of lamotrigine and gabapentin in the treatment of trigeminal neuralgia.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Trigeminal Neuralgia | 1998 |
Effects of phenytoin, carbamazepine, and gabapentin on calcium channels in hippocampal granule cells from patients with temporal lobe epilepsy.
Topics: Acetates; Adult; Amines; Anticonvulsants; Calcium Channels; Carbamazepine; Cyclohexanecarboxylic Acids; Dentate Gyrus; Epilepsy, Temporal Lobe; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Humans; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phenytoin; Pyramidal Cells | 1998 |
Anticonvulsant action of gabapentin during postnatal development in rats.
Topics: Acetates; Amines; Animals; Anticonvulsants; Behavior, Animal; Brain; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Gabapentin; gamma-Aminobutyric Acid; Male; Pentylenetetrazole; Rats; Rats, Wistar; Seizures | 1997 |
Failure of absorption of gabapentin after rectal administration.
Topics: Acetates; Administration, Oral; Administration, Rectal; Adolescent; Amines; Anticonvulsants; Biological Availability; Child; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Hospitalization; Humans; Intestinal Absorption; Intestinal Mucosa; Male; Rectum | 1997 |
Effects of systemic carbamazepine and gabapentin on spinal neuronal responses in spinal nerve ligated rats.
Topics: Acetates; Amines; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Cyclohexanecarboxylic Acids; Electric Stimulation; Electrophysiology; Evoked Potentials; Gabapentin; gamma-Aminobutyric Acid; Humans; Ligation; Male; Neurons; Rats; Rats, Sprague-Dawley; Spinal Nerves | 1998 |
New approaches to therapy of amyotrophic lateral sclerosis.
Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Animals; Brain-Derived Neurotrophic Factor; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Insulin-Like Growth Factor I; Mice; Riluzole | 1998 |
Glutamate, glutamine, and GABA as substrates for the neuronal and glial compartments after focal cerebral ischemia in rats.
Topics: Acetates; Amino Acids; Animals; Arteries; Blood Pressure; Brain; Brain Ischemia; Carbon Isotopes; Cytosol; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hydrogen; Infusions, Intravenous; Magnetic Resonance Spectroscopy; Neuroglia; Neurons; Rats; Rats, Inbred Strains; Substrate Specificity; Tissue Extracts; Veins | 1998 |
Gabapentin in geriatric psychiatry patients.
Topics: Acetates; Aged; Aged, 80 and over; Alzheimer Disease; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Dementia; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 1998 |
Activation of two types of brain glutamate dehydrogenase isoproteins by gabapentin.
Topics: Acetates; Amines; Animals; Anticonvulsants; Brain; Cattle; Cyclohexanecarboxylic Acids; Enzyme Activation; Gabapentin; gamma-Aminobutyric Acid; Glutamate Dehydrogenase; Guanosine Triphosphate; Isoenzymes; Kinetics; Oxidation-Reduction | 1998 |
Identification of novel ligands for the gabapentin binding site on the alpha2delta subunit of a calcium channel and their evaluation as anticonvulsant agents.
Topics: Acetates; Amines; Animals; Anticonvulsants; Binding Sites; Calcium Channels; Cyclohexanecarboxylic Acids; Cyclohexanes; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Ligands; Male; Mice; Semicarbazides; Stereoisomerism; Structure-Activity Relationship | 1998 |
Increased seizure frequency associated with felbamate withdrawal in adults.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Phenylcarbamates; Propylene Glycols; Retrospective Studies; Seizures; Substance Withdrawal Syndrome; Treatment Outcome | 1998 |
Clinical experience using gabapentin adjunctively in patients with a history of mania or hypomania.
Topics: Acetates; Adult; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome | 1998 |
Reduction of 3,4-diaminopyridine-induced biogenic amine synthesis and release in rat brain by gabapentin.
Topics: 4-Aminopyridine; 5-Hydroxytryptophan; Acetates; Amifampridine; Amines; Animals; Anticonvulsants; Biogenic Monoamines; Brain; Cyclohexanecarboxylic Acids; Dihydroxyphenylalanine; Dopamine; Gabapentin; gamma-Aminobutyric Acid; Male; Rats; Rats, Sprague-Dawley | 1998 |
[Prophylactic treatment with gabapentin in chronic daily headache resistant to other drugs].
Topics: Acetates; Adult; Aged; Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Resistance; Female; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Male; Middle Aged | 1998 |
Gabapentin in the treatment of adolescent mania: a case report.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Psychiatric Status Rating Scales | 1998 |
Gabapentin potentiation of the antiepileptic efficacy of vigabatrin in an in vitro model of epilepsy.
Topics: 4-Aminobutyrate Transaminase; Acetates; Amines; Animals; Anticonvulsants; Bicuculline; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Epilepsy; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Magnesium Deficiency; Polypharmacy; Seizures; Vigabatrin | 1998 |
Gabapentin as a potential treatment for anxiety disorders.
Topics: Acetates; Adult; Alprazolam; Amines; Anticonvulsants; Anxiety Disorders; Cyclohexanecarboxylic Acids; Diazepam; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Panic Disorder; Phobic Disorders | 1998 |
Gabapentin potentiates the antiseizure activity of certain anticonvulsants in DBA/2 mice.
Topics: Acetates; Acoustic Stimulation; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Synergism; Female; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred DBA; Seizures | 1998 |
Negative modultors of excitatory amino acids in episodic and chronic migraine: preventing and reverting chronic migraine. Special lecture 7th INWIN Congress.
Topics: Acetates; Adult; Amines; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Humans; Ketamine; Male; Middle Aged; Migraine Disorders; Receptors, N-Methyl-D-Aspartate; Transaminases | 1998 |
Gabapentin inhibits calcium currents in isolated rat brain neurons.
Topics: Acetates; Amines; Animals; Anticonvulsants; Brain; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Globus Pallidus; Male; Neocortex; Neostriatum; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar | 1998 |
Role of branched-chain aminotransferase isoenzymes and gabapentin in neurotransmitter metabolism.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Acetates; Amines; Animals; Animals, Newborn; Anticonvulsants; Astrocytes; Carbon Radioisotopes; Cells, Cultured; Cerebral Cortex; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Isoenzymes; Ketone Oxidoreductases; Mitochondria; Multienzyme Complexes; Neurons; Neurotransmitter Agents; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Transaminases | 1998 |
Advances in mood stabilizing medications.
Topics: Acetates; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium Carbonate; Thyrotropin-Releasing Hormone; Triazines | 1998 |
Attenuation of formalin-induced nociceptive behaviors following local peripheral injection of gabapentin.
Topics: Acetates; Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Injections, Subcutaneous; Male; Nociceptors; Pain; Pain Measurement; Pregabalin; Rats; Rats, Sprague-Dawley; Serine | 1998 |
An open-label trial of gabapentin treatment of paroxysmal symptoms in multiple sclerosis patients.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Multiple Sclerosis; Pain Measurement; Spasm | 1998 |
Gabapentin relieves trigeminal neuralgia in multiple sclerosis patients.
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multiple Sclerosis; Trigeminal Neuralgia | 1998 |
A high-performance liquid chromatography micromethod for the simultaneous determination of vigabatrin and gabapentin in serum.
Topics: Acetates; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Microchemistry; Sensitivity and Specificity; Vigabatrin | 1998 |
Gabapentin treatment of mood disorders: a preliminary study.
Topics: Acetates; Adolescent; Adult; Aged; Ambulatory Care; Amines; Anticonvulsants; Antidepressive Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Depressive Disorder; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Mood Disorders; Pilot Projects; Psychiatric Status Rating Scales; Retrospective Studies; Treatment Outcome | 1998 |
Cost-efficient use of gas chromatography-mass spectrometry: a "piggyback" method for analysis of gabapentin.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans | 1998 |
[ETICS Study: Empirical therapy of idiopathic chronic singultus].
Topics: Acetates; Aged; Aged, 80 and over; Amines; Baclofen; Chronic Disease; Cisapride; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Agents; Hiccup; Humans; Male; Middle Aged; Omeprazole; Treatment Outcome | 1998 |
Gabapentin for disruptive behaviour in an elderly demented patient.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dementia; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; New York; Nursing Homes; Psychomotor Agitation | 1998 |
Effective treatment of orthostatic tremor with gabapentin.
Topics: Acetates; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Electromyography; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Isometric Contraction; Male; Middle Aged; Postural Balance; Posture; Tremor; Weight-Bearing | 1998 |
Renal impairment as a possible side effect of gabapentin. A single case report.
Topics: Acetates; Adult; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Diseases; Male | 1998 |
[Treatment of neuropathic pain with gabapentin ++].
Topics: Acetates; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia | 1998 |
The outcome of prescribing novel anticonvulsants in an outpatient setting: factors affecting response to medication.
Topics: Acetates; Adolescent; Adult; Ambulatory Care; Amines; Anticonvulsants; Chi-Square Distribution; Cyclohexanecarboxylic Acids; Drug Prescriptions; Epilepsy; Female; Follow-Up Studies; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Patient Compliance; Retrospective Studies; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Wales | 1998 |
Treatment of seizures in acute intermittent porphyria: safety and efficacy of gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Porphyria, Acute Intermittent; Treatment Outcome | 1998 |
Lamotrigine inhibits monoamine uptake in vitro and modulates 5-hydroxytryptamine uptake in rats.
Topics: Acetates; Amines; Animals; Anticonvulsants; Biogenic Amines; Blood Platelets; Brain; Carbamazepine; Cyclohexanecarboxylic Acids; Dopamine; Dopamine Uptake Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Lithium; Male; Norepinephrine; p-Chloroamphetamine; Phenytoin; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Syndrome; Synaptosomes; Tetrodotoxin; Triazines; Valproic Acid; Zonisamide | 1998 |
Systemic gabapentin and S(+)-3-isobutyl-gamma-aminobutyric acid block secondary hyperalgesia.
Topics: Acetates; Amines; Animals; Anticonvulsants; Burns; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Intraperitoneal; Male; Pain Threshold; Pregabalin; Rats; Rats, Sprague-Dawley | 1998 |
Stevens-Johnson syndrome associated with gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Stevens-Johnson Syndrome | 1998 |
A case of spinal cord injury-related pain with baseline rCBF brain SPECT imaging and beneficial response to gabapentin.
Topics: Acetates; Adult; Amines; Analgesics; Brain; Cerebrovascular Circulation; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain; Spinal Cord Injuries; Tomography, Emission-Computed, Single-Photon | 1998 |
The anti-allodynic effects of amitriptyline, gabapentin, and lidocaine in a rat model of neuropathic pain.
Topics: Acetates; Amines; Amitriptyline; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Infusions, Intravenous; Infusions, Parenteral; Lidocaine; Male; Neuralgia; Pain Threshold; Rats; Rats, Sprague-Dawley | 1998 |
Symptomatic treatment of painful neuropathy.
Topics: Acetates; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia; Pain | 1998 |
In vivo monitoring of gabapentin in rats: a microdialysis study coupled to capillary electrophoresis and laser-induced fluorescence detection.
Topics: Acetates; Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Electrophoresis, Capillary; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Gabapentin; gamma-Aminobutyric Acid; Hemofiltration; Male; Microdialysis; Rats; Rats, Wistar | 1998 |
Comments on Gould, PAIN, 74 (1998) 341-343.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrocephalus, Normal Pressure; Male; Peripheral Nervous System Diseases | 1998 |
Gabapentin for treatment of neuropathic pain in a 12-year-old girl.
Topics: Acetates; Amines; Child; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Nervous System Diseases; Pain; Postoperative Complications; Thoracotomy | 1998 |
A case of myokymia-cramp syndrome successfully treated with gabapentin.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Extremities; Fasciculation; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Muscle Cramp; Syndrome; Treatment Outcome | 1998 |
Pharmacological and neuroanatomical studies of the antinociceptive effects of intrathecally administered gabapentin.
Topics: Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Rats; Rats, Sprague-Dawley; Spinal Cord; Synaptic Transmission | 1998 |
Possible gabapentin-induced thyroiditis.
Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Thyroiditis | 1999 |
Gabapentin suppresses ectopic nerve discharges and reverses allodynia in neuropathic rats.
Topics: Acetates; Afferent Pathways; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electrophysiology; Exploratory Behavior; Gabapentin; gamma-Aminobutyric Acid; Male; Pain; Peripheral Nerve Injuries; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 1999 |
Skin eruption with gabapentin in a patient with repeated AED-induced Stevens-Johnson's syndrome.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Hypersensitivity; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Skin Diseases; Stevens-Johnson Syndrome | 1999 |
Gabapentin for painful diabetic neuropathy.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Randomized Controlled Trials as Topic; Reproducibility of Results | 1999 |
The reduction in paired-pulse inhibition in the rat hippocampus by gabapentin is independent of GABA(B) receptor receptor activation.
Topics: Acetates; Amines; Animals; Anticonvulsants; Baclofen; Cyclohexanecarboxylic Acids; Dentate Gyrus; Electric Stimulation; GABA Agonists; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Neural Inhibition; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 1999 |
Neuropathic pain after anti-HIV gene therapy successfully treated with gabapentin.
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Genetic Therapy; HIV Infections; Humans; Male; Pain Management; Peripheral Nervous System Diseases | 1999 |
An in vitro electrophysiological study on the effects of phenytoin, lamotrigine and gabapentin on striatal neurons.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Cerebral Cortex; Corpus Striatum; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Lamotrigine; Male; Membrane Potentials; Neurons; Phenytoin; Rats; Rats, Wistar; Triazines | 1999 |
Gabapentin prevents hyperalgesia during the formalin test in diabetic rats.
Topics: Acetates; Amines; Analgesics; Animals; Blood Glucose; Body Weight; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Female; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hyperalgesia; Pain Measurement; Rats; Rats, Sprague-Dawley | 1999 |
Gabapentin and pregabalin, but not morphine and amitriptyline, block both static and dynamic components of mechanical allodynia induced by streptozocin in the rat.
Topics: Acetates; Amines; Amitriptyline; Analgesics; Animals; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hyperglycemia; Injections; Injections, Spinal; Male; Morphine; Pain; Physical Stimulation; Pregabalin; Rats; Rats, Sprague-Dawley; Skin; Streptozocin; Touch | 1999 |
Development of two stable oral suspensions for gabapentin.
Topics: Acetates; Administration, Oral; Amines; Anticonvulsants; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Compounding; Drug Stability; Drug Storage; Gabapentin; gamma-Aminobutyric Acid; Reproducibility of Results; Suspensions | 1999 |
Gabapentin as monotherapy in the treatment of acute mania.
Topics: Acetates; Acute Disease; Adult; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 1999 |
Catatonia following gabapentin withdrawal.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Substance Withdrawal Syndrome | 1999 |
[Use of gabapentin in glossopharyngeal neuralgia].
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Glossopharyngeal Nerve; Humans; Male; Middle Aged; Neuralgia; Treatment Outcome | 1999 |
Gabapentin decreases the severity of dystonia at low doses in a genetic animal model of paroxysmal dystonic choreoathetosis.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cricetinae; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid | 1999 |
Transport of pregabalin in rat intestine and Caco-2 monolayers.
Topics: Acetates; Amines; Amino Acids; Animals; Anticonvulsants; Biological Transport; Caco-2 Cells; Colon; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ileum; In Vitro Techniques; Intestinal Mucosa; Male; Mannitol; Phenylalanine; Pregabalin; Rats; Rats, Sprague-Dawley | 1999 |
Gabapentin modifies extracellular opioid peptide content in amygdala: a microdialysis study.
Topics: Acetates; Amines; Amygdala; Animals; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Extracellular Space; Gabapentin; gamma-Aminobutyric Acid; Male; Microdialysis; Opioid Peptides; Radioimmunoassay; Rats; Rats, Wistar; Synaptic Transmission | 1999 |
Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Lamotrigine; Male; Motor Activity; Pain Measurement; Phenols; Piperidines; Pyrrolidinones; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Triazines | 1999 |
The management of epilepsy in a hospital for people with a learning disability.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Utilization; Epilepsy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Health Surveys; Hospitals, Psychiatric; Humans; Lamotrigine; Learning Disabilities; Male; Middle Aged; Phenobarbital; Triazines; United Kingdom; Vigabatrin | 1999 |
Successful treatment with gabapentin in the presence of hypersensitivity syndrome to phenytoin and carbamazepine: a report of three cases.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Hypersensitivity; Drug Interactions; Epilepsy, Complex Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Phenytoin; Valproic Acid | 1999 |
Gabapentin-induced ejaculatory failure and anorgasmia.
Topics: Acetates; Adult; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Ejaculation; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Orgasm; Sexual Dysfunction, Physiological; Sexual Dysfunctions, Psychological | 1999 |
Mood stabilizer combinations for bipolar disorder.
Topics: Acetates; Adolescent; Age Factors; Amines; Antimanic Agents; Bipolar Disorder; Child; Cyclohexanecarboxylic Acids; Drug Eruptions; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Triazines; Valproic Acid | 1999 |
Rapid high-performance liquid chromatographic determination of serum gabapentin.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Child; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 1999 |
Automated microanalysis of gabapentin in human serum by high-performance liquid chromatography with fluorometric detection.
Topics: Acetates; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 1999 |
A patient with multiple sclerosis and Down's syndrome with a rare paroxysmal symptom at onset.
Topics: Acetates; Amines; Brain; Cyclohexanecarboxylic Acids; Down Syndrome; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis; Pelvic Pain; Triazines | 1999 |
Gabapentin for self-injurious behavior in Lesch-Nyhan syndrome.
Topics: Acetates; Amines; Child, Preschool; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Lesch-Nyhan Syndrome; Male; Self-Injurious Behavior; Treatment Outcome | 1999 |
Gabapentin attenuates nociceptive behaviors in an acute arthritis model in rats.
Topics: Acetates; Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Behavior, Animal; Carrageenan; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hot Temperature; Hyperalgesia; Injections, Spinal; Injections, Subcutaneous; Joints; Kaolin; Pain Measurement; Rats; Rats, Sprague-Dawley | 1999 |
Gabapentin as treatment for hemifacial spasm.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Hemifacial Spasm; Humans; Male; Middle Aged; Time Factors; Treatment Outcome | 1999 |
An in vitro investigation into conformational aspects of gabapentin.
Topics: Acetates; Amines; Anticonvulsants; Calcium Channels; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Isomerism; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Protein Binding; Protein Conformation; Temperature | 1999 |
Gabapentin for painful diabetic neuropathy.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain | 1999 |
Gabapentin for painful diabetic neuropathy.
Topics: Acetates; Amines; Analgesics; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain | 1999 |
Gabapentin for postherpetic neuralgia.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia | 1999 |
Behavioral effects of RS-45041-190, a selective I2 imidazoline ligand, in rats.
Topics: Acetates; Amines; Analgesics; Animals; Carrageenan; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Imidazoles; Imidazoline Receptors; Indoles; Injections, Intraperitoneal; Injections, Spinal; Isoindoles; Ligands; Male; Motor Activity; Pain; Rats; Rats, Sprague-Dawley; Receptors, Drug | 1999 |
The effect of intrathecal gabapentin on pain behavior and hemodynamics on the formalin test in the rat.
Topics: Acetates; Amines; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Hemodynamics; Hindlimb; Injections, Spinal; Male; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley | 1999 |
Structural requirement of the calcium-channel subunit alpha2delta for gabapentin binding.
Topics: Acetates; Amines; Amino Acid Sequence; Animals; Anticonvulsants; Base Sequence; Binding Sites; Calcium Channels; COS Cells; Cyclohexanecarboxylic Acids; Disulfides; DNA Primers; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Point Mutation; Protein Structure, Quaternary; Recombinant Proteins; Sequence Deletion; Swine; Transfection | 1999 |
Use of gabapentin to treat taxane-induced myalgias.
Topics: Acetates; Amines; Analgesics; Antineoplastic Agents, Phytogenic; Cyclohexanecarboxylic Acids; Docetaxel; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Muscular Diseases; Paclitaxel; Pain; Taxoids | 1999 |
The race to control pain: more participants, more targets.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Nicotinic Agonists; Pain; Receptors, Drug; Sodium Channels | 1999 |
Gabapentin as a promising treatment for antipsychotic-induced movement disorders in schizoaffective and bipolar patients.
Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Antipsychotic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Dyskinesia, Drug-Induced; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Psychotic Disorders; Treatment Outcome | 1999 |
Gabapentin for the treatment of dysesthetic pain after reconstructive surgery.
Topics: Acetates; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Paresthesia; Plastic Surgery Procedures | 1999 |
The TamA protein fused to a DNA-binding domain can recruit AreA, the major nitrogen regulatory protein, to activate gene expression in Aspergillus nidulans.
Topics: Acetates; Aspergillus nidulans; Aspergillus oryzae; DNA-Binding Proteins; DNA, Fungal; Fungal Proteins; gamma-Aminobutyric Acid; Gene Expression Regulation, Fungal; Genes, Fungal; Genetic Complementation Test; Mutation; Neurospora crassa; Nitrogen; Promoter Regions, Genetic; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Trans-Activators; Transcription Factors | 1999 |
Synthesis and biological evaluation of conformationally restricted Gabapentin analogues.
Topics: Acetates; Amines; Analgesics, Non-Narcotic; Animals; Convulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Molecular Structure; Rats | 1999 |
Neuropathic pain.
Topics: Acetates; Amines; Amitriptyline; Analgesics; Antiviral Agents; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia | 1999 |
Lesson of the month: Systemic vasculitis or not? That is the question.
Topics: Acetates; Amines; Anticoagulants; Anticonvulsants; Brain; Carbamazepine; Central Nervous System Diseases; Clotrimazole; Cyclohexanecarboxylic Acids; Cyclophosphamide; Drug Hypersensitivity; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Immunosuppressive Agents; Liver; Magnetic Resonance Imaging; Male; Middle Aged; Vasculitis; Vasculitis, Leukocytoclastic, Cutaneous; Warfarin | 1999 |
Saturable transport of gabapentin at the blood-brain barrier.
Topics: Acetates; Amines; Animals; Anticonvulsants; Blood-Brain Barrier; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Plasma Exchange; Rats; Rats, Sprague-Dawley | 1999 |
Inhibition of uptake, steady-state currents, and transient charge movements generated by the neuronal GABA transporter by various anticonvulsant drugs.
Topics: Acetates; Amines; Animals; Anticonvulsants; Binding Sites; Biological Transport; Carrier Proteins; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electric Conductivity; Female; GABA Plasma Membrane Transport Proteins; Gabapentin; gamma-Aminobutyric Acid; Kinetics; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Mice; Nipecotic Acids; Oocytes; Organic Anion Transporters; Patch-Clamp Techniques; Tiagabine; Valproic Acid; Vigabatrin; Xenopus laevis | 1999 |
Gabapentin for the management of agitation.
Topics: Acetates; Aggression; Amines; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Psychomotor Agitation | 1999 |
Using gabapentin to treat neuropathic pain.
Topics: Acetates; Adult; Amines; Analgesics; Anticonvulsants; Costs and Cost Analysis; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain, Postoperative; Time Factors | 1999 |
Gabapentin as an adjunctive treatment in bipolar disorder.
Topics: Acetates; Adult; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Psychiatric Status Rating Scales | 1999 |
Evaluation of interaction between gabapentin and ibuprofen on the formalin test in rats.
Topics: Acetates; Amines; Analgesics; Analgesics, Non-Narcotic; Animals; Blood Pressure; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Ibuprofen; Injections, Intraperitoneal; Male; Pain Measurement; Rats; Rats, Sprague-Dawley | 1999 |
A case report of reduction in alcohol craving and protection against alcohol withdrawal by gabapentin.
Topics: Acetates; Adult; Alcohol Drinking; Alcoholism; Amines; Animals; Anticonvulsants; Comorbidity; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Ethanol; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mice; Obsessive-Compulsive Disorder; Substance Withdrawal Syndrome | 1999 |
An 8-year-old girl with unilateral facial and ear pain and isolated frontal headaches.
Topics: Acetates; Amines; Child; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Earache; Face; Female; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Melkersson-Rosenthal Syndrome; Physician-Patient Relations; Professional Competence; Severity of Illness Index; Temporomandibular Joint Disorders; Tongue, Fissured | 1999 |
The long-term use of gabapentin, lamotrigine, and vigabatrin in patients with chronic epilepsy.
Topics: Acetates; Ambulatory Care; Amines; Anticonvulsants; Chronic Disease; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Longitudinal Studies; Medical Records; Multicenter Studies as Topic; Patient Dropouts; Pharmacoepidemiology; Proportional Hazards Models; Retrospective Studies; Survival Analysis; Treatment Outcome; Triazines; United Kingdom; Vigabatrin | 1999 |
Antinociceptive effect of gabapentin in the formalin test.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Male; Nociceptors; Pain Measurement; Rats; Rats, Wistar | 1999 |
Effects of ammonia on the anaplerotic pathway and amino acid metabolism in the brain: an ex vivo 13C NMR spectroscopic study of rats after administering [2-13C]] glucose with or without ammonium acetate.
Topics: Acetates; Amino Acids; Ammonia; Animals; Aspartic Acid; Brain; Carbon Isotopes; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Kinetics; Magnetic Resonance Spectroscopy; Male; Models, Chemical; Models, Neurological; Neuroglia; Neurons; Pyruvate Carboxylase; Rats; Rats, Sprague-Dawley; Time Factors | 1999 |
Anticonvulsant activity of PNU-151774E in the amygdala kindled model of complex partial seizures.
Topics: Acetates; Alanine; Amines; Amygdala; Animals; Anticonvulsants; Behavior, Animal; Benzylamines; Carbamazepine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Complex Partial; Gabapentin; gamma-Aminobutyric Acid; Kindling, Neurologic; Lamotrigine; Male; Phenytoin; Rats; Rats, Wistar; Severity of Illness Index; Triazines | 1999 |
Antidepressant-induced bruxism successfully treated with gabapentin.
Topics: Acetates; Amines; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Bipolar Disorder; Bruxism; Cyclohexanecarboxylic Acids; Cyclohexanols; Depression; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Venlafaxine Hydrochloride | 1999 |
Neurontin: expanding the clinical experience. Proceedings of a symposium. Cannes, France, June 5, 1998.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans | 1999 |
Gabapentin therapy for vulvodynia.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pelvic Pain; Vulvar Diseases | 1999 |
On call. I am a 49-year-old man with diabetes. I take Glucophage and I'm careful with my diet. I also walk three miles almost every day. My blood sugar is always below 150, usually in the 130s. My problem is tingling in my fingers and pain in my feet, whi
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 2000 |
Gabapentin-induced anorgasmia.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Orgasm; Pain, Postoperative; Thoracotomy | 1999 |
Gabapentin leads to remission of somatoform pain disorder with major depression.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Depressive Disorder; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Inguinal Canal; Middle Aged; Pain; Somatoform Disorders; Time Factors | 1999 |
A case of sustained massive gabapentin overdose without serious side effects.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cognition; Cyclohexanecarboxylic Acids; Drug Overdose; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Renal Insufficiency; Time Factors; Tremor; Valproic Acid | 1999 |
Open maintenance treatment of bipolar disorder spectrum patients who responded to gabapentin augmentation in the acute phase of treatment.
Topics: Acetates; Acute Disease; Adult; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Recurrence; Treatment Outcome | 1999 |
Cognitive effects of topiramate, gabapentin, and lamotrigine in healthy young adults.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cognition; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Topiramate; Triazines | 2000 |
Cognitive effects of topiramate, gabapentin, and lamotrigine in healthy young adults.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cognition; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Topiramate; Triazines | 2000 |
Intrathecally administered gabapentin inhibits formalin-evoked nociception and the expression of Fos-like immunoreactivity in the spinal cord of the rat.
Topics: Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Foot; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Immunohistochemistry; Injections, Spinal; Male; Neurons; Nociceptors; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord; Time Factors | 2000 |
Gabapentin treatment for brachioradial pruritus.
Topics: Acetates; Administration, Oral; Amines; Arm; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Female; Forearm; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pruritus | 1999 |
Manic episode due to gabapentin treatment.
Topics: Acetates; Adult; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans | 1999 |
Refractory epilepsy: treatment with new antiepileptic drugs.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Resistance; Drug Therapy, Combination; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Nipecotic Acids; Patient Dropouts; Retrospective Studies; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin | 2000 |
Gabapentin treatment in a child with delayed-onset hemichorea/hemiballismus.
Topics: Acetates; Adolescent; Age of Onset; Amines; Antiparkinson Agents; Basal Ganglia; Chorea; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Dyskinesias; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Neural Pathways; Stroke; Treatment Outcome | 2000 |
Repeated administration of systemic gabapentin alleviates allodynia-like behaviors in spinally injured rats.
Topics: Acetates; Amines; Analgesics; Animals; Cold Temperature; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Pain; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Time Factors | 2000 |
Treatment of dementia-associated agitation with gabapentin.
Topics: Acetates; Aged; Aged, 80 and over; Alzheimer Disease; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dementia, Multi-Infarct; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mental Status Schedule; Neurologic Examination; Psychomotor Agitation | 2000 |
Gabapentin as add-on therapy in focal epilepsy: a computerized EEG study.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Brain; Brain Mapping; Cyclohexanecarboxylic Acids; Electroencephalography; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 2000 |
Gabapentin-lactam, a close analogue of the anticonvulsant gabapentin, exerts convulsant activity in amygdala kindled rats.
Topics: Acetates; Amines; Amygdala; Animals; Anticonvulsants; Aza Compounds; Convulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Kindling, Neurologic; Rats; Rats, Wistar; Spiro Compounds | 2000 |
Inhibition of K(+)-evoked glutamate release from rat neocortical and hippocampal slices by gabapentin.
Topics: Acetates; Agatoxins; Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Neocortex; omega-Conotoxins; Potassium; Pregabalin; Rats; Rats, Sprague-Dawley; Spider Venoms | 2000 |
Gabapentin, an antiepileptic drug, improves memory storage in mice.
Topics: Acetates; Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Male; Memory; Mice; Mice, Inbred Strains | 2000 |
Synergistic effect between intrathecal non-NMDA antagonist and gabapentin on allodynia induced by spinal nerve ligation in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Ligation; Male; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley; Spinal Nerves | 2000 |
Combination of donepezil and gabapentin for behavioral disorders in Alzheimer's disease.
Topics: Acetates; Aged; Aged, 80 and over; Alzheimer Disease; Amines; Anticonvulsants; Cholinesterase Inhibitors; Cyclohexanecarboxylic Acids; Donepezil; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Indans; Male; Mental Disorders; Piperidines; Psychiatric Status Rating Scales; Treatment Outcome | 2000 |
Gabapentin prophylaxis of clozapine-induced seizures.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Antipsychotic Agents; Clozapine; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Schizophrenia; Secondary Prevention; Treatment Outcome | 2000 |
Improved sexual function in three men taking lamotrigine for epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy, Complex Partial; Epilepsy, Temporal Lobe; Erectile Dysfunction; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Sexual Dysfunctions, Psychological; Triazines; Valproic Acid | 2000 |
Use of gabapentin in the treatment of childhood reflex sympathetic dystrophy.
Topics: Acetates; Amines; Child; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Leg; Recurrence; Reflex Sympathetic Dystrophy; Treatment Outcome | 2000 |
Antiallodynic effect of intrathecal gabapentin and its interaction with clonidine in a rat model of postoperative pain.
Topics: Acetates; Adrenergic alpha-Agonists; Amines; Amino Acids; Amino Acids, Cyclic; Analgesics; Animals; Behavior, Animal; Clonidine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Leucine; Male; Pain Threshold; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Reflex | 2000 |
Myoclonus associated with the use of gabapentin.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Myoclonus; Severity of Illness Index | 2000 |
Allosteric modulation of [(3)H]gabapentin binding by ruthenium red.
Topics: Acetates; Amines; Animals; Anticonvulsants; Binding Sites; Binding, Competitive; Calcium Channels; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Ligands; Magnesium Chloride; Membranes; Mice; Ruthenium Red; Spermine; Temperature | 2000 |
Gabapentin vs amitriptyline for the treatment of peripheral neuropathy.
Topics: Acetates; Amines; Amitriptyline; Analgesics, Non-Narcotic; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia | 2000 |
Gabapentin. CI 945, GOE 3450, Neurontin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Area Under Curve; Biological Availability; Child; Child, Preschool; Clinical Trials as Topic; Cross-Over Studies; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Leukemia, Myeloid, Acute; Migraine Disorders; Phobic Disorders | 1999 |
Dystonia in a patient treated with propranolol and gabapentin.
Topics: Acetates; Adrenergic beta-Antagonists; Aged; Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Drug Synergism; Dystonia; Essential Tremor; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Propranolol | 2000 |
Anticonvulsant efficacy of gabapentin and levetiracetam in phenytoin-resistant kindled rats.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Evaluation; Drug Resistance; Female; Gabapentin; gamma-Aminobutyric Acid; Kindling, Neurologic; Levetiracetam; Phenytoin; Piracetam; Rats; Rats, Wistar; Seizures | 2000 |
Complex regional pain syndrome (CRPS) with resistance to local anesthetic block: a case report.
Topics: Acetates; Amines; Amitriptyline; Analgesia, Epidural; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Child; Cyclohexanecarboxylic Acids; Drug Resistance; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrocodone; Lidocaine; Nerve Block; Physical Therapy Modalities; Posterior Horn Cells; Receptors, N-Methyl-D-Aspartate; Reflex Sympathetic Dystrophy; Sympathetic Nervous System | 2000 |
Analysis of relations between NMDA receptors and GABA release at olfactory bulb reciprocal synapses.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetates; Animals; Cadmium; Calcium; Calcium Channels; Chelating Agents; Dendrites; Enzyme Inhibitors; Ethylenediamines; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Feedback; gamma-Aminobutyric Acid; Membrane Potentials; Neural Inhibition; Neurotransmitter Agents; Nickel; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synapses; Thapsigargin | 2000 |
Gabapentin "add-on therapy" for idiopathic chronic hiccup (ICH).
Topics: Acetates; Aged; Amines; Baclofen; Chronic Disease; Cisapride; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Agents; Hiccup; Humans; Male; Middle Aged; Muscle Relaxants, Central; Omeprazole; Treatment Outcome | 2000 |
Gabapentin affects glutamatergic excitatory neurotransmission in the rat dorsal horn.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Excitatory Postsynaptic Potentials; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Neurons, Afferent; Neurotransmitter Agents; Nociceptors; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic; Synaptic Transmission | 2000 |
Changes in use of valproate and other mood stabilizers for patients with schizophrenia from 1994 to 1998.
Topics: Acetates; Adult; Amines; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Drug Utilization; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium Carbonate; Male; Middle Aged; New York; Retrospective Studies; Schizophrenia; Schizophrenic Psychology; Valproic Acid | 2000 |
Gabapentin-induced mitogenic activity in rat pancreatic acinar cells.
Topics: Acetates; Amines; Animals; Binding, Competitive; Calcium; Cell Division; Cell Line; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Gene Expression Regulation, Neoplastic; Genes, Immediate-Early; Mitogens; Organ Size; Pancreas; Rats; Rats, Wistar; Receptors, Cholecystokinin | 2000 |
Paroxysmal dystonia induced by exercise and acetazolamide.
Topics: Acetates; Acetazolamide; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dystonia; Exercise; Female; Gabapentin; gamma-Aminobutyric Acid; Humans | 2000 |
Gabapentin for treatment of thalamic pain syndrome.
Topics: Acetates; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain; Palliative Care; Thalamic Diseases | 2000 |
Anorgasmia in a patient with bipolar disorder type 1 treated with gabapentin.
Topics: Acetates; Adult; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Orgasm; Sexual Dysfunction, Physiological | 2000 |
Effects of gabapentin on brain GABA, homocarnosine, and pyrrolidinone in epilepsy patients.
Topics: Acetates; Adult; Amines; Anticonvulsants; Brain Chemistry; Carnosine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Occipital Lobe; Pyrrolidinones | 2000 |
Antinociceptive effect of gabapentin in rats.
Topics: Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Male; Pain Measurement; Rats; Rats, Wistar | 2000 |
Gabapentin's effects on hot flashes and hypothermia.
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Hypothermia; Male; Middle Aged; Migraine Disorders | 2000 |
A microdialysis study on the mechanism of action of gabapentin.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Nipecotic Acids; Potassium; Proline; Rats; Rats, Wistar; Substantia Nigra | 2000 |
Inhibition of neuronal Ca(2+) influx by gabapentin and subsequent reduction of neurotransmitter release from rat neocortical slices.
Topics: 2-Amino-5-phosphonovalerate; Acetates; Amines; Animals; Aspartic Acid; Calcium; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Male; Neostriatum; Neurons; Neurotransmitter Agents; Norepinephrine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Potassium; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Synaptosomes; Tritium | 2000 |
The anticonvulsant compound gabapentin possesses anxiolytic but not amnesic effects in rats.
Topics: Acetates; Amines; Amnesia; Animals; Anti-Anxiety Agents; Anticonvulsants; Avoidance Learning; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Memory; Rats; Rats, Wistar | 2000 |
Gabapentin in seizures due to acute intermittent porphyria.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Porphyria, Acute Intermittent; Seizures | 2000 |
A comparison of four new antiepileptic medications.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy, Complex Partial; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Medical Records; Middle Aged; Retrospective Studies; Survival Analysis; Topiramate; Treatment Outcome; Triazines; Vigabatrin | 2000 |
Gabapentin in acute painful diabetic neuropathy.
Topics: Acetates; Acute Disease; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Palliative Care | 2000 |
Low-dose gabapentin combined with either lamotrigine or carbamazepine can be useful therapies for trigeminal neuralgia in multiple sclerosis.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Pain Measurement; Triazines; Trigeminal Neuralgia | 2000 |
A retrospective chart review of gabapentin for the treatment of aggressive and agitated behavior in patients with dementias.
Topics: Acetates; Aged; Aged, 80 and over; Aggression; Amines; Antimanic Agents; California; Cyclohexanecarboxylic Acids; Dementia; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Inpatients; Male; Medical Records; Middle Aged; Nursing Homes; Retrospective Studies; Social Behavior Disorders; Treatment Outcome | 2000 |
Gabapentin may be hazardous in myasthenia gravis.
Topics: Acetates; Action Potentials; Aged; Amines; Animals; Anticonvulsants; Autoantibodies; Cholinesterase Inhibitors; Contraindications; Cyclohexanecarboxylic Acids; Electric Stimulation; Electrophysiology; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Myasthenia Gravis; Pyridostigmine Bromide; Rats; Rats, Inbred Lew; Receptors, Cholinergic | 2000 |
Reversible acute renal allograft dysfunction due to gabapentin.
Topics: Acetates; Acute Disease; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney; Kidney Transplantation | 2000 |
Treating hot flashes with drugs.
Topics: Acetates; Adrenergic alpha-Antagonists; Amines; Anticonvulsants; Clonidine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hormone Replacement Therapy; Hot Flashes; Humans; Selective Serotonin Reuptake Inhibitors | 2000 |
Herpes zoster.
Topics: Acetates; Acute Disease; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia | 2000 |
Morphine and gabapentin decrease mechanical hyperalgesia and escape/avoidance behavior in a rat model of neuropathic pain.
Topics: Acetates; Amines; Analgesics; Animals; Avoidance Learning; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Morphine; Nerve Crush; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Sprague-Dawley | 2000 |
The effects of gabapentin in the rat hippocampus are mimicked by two structural analogs, but not by nimodipine.
Topics: Acetates; Amines; Animals; Anticonvulsants; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Cyclohexanes; Dentate Gyrus; Diazepam; Dose-Response Relationship, Drug; Electric Stimulation; Gabapentin; gamma-Aminobutyric Acid; Male; Neural Inhibition; Nimodipine; Pregabalin; Rats; Rats, Sprague-Dawley; Reaction Time; Seizures | 2000 |
Gabapentin for treatment of bipolar and schizoaffective disorders.
Topics: Acetates; Adult; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Psychotic Disorders | 1997 |
Gabapentin inhibits excitatory synaptic transmission in the hyperalgesic spinal cord.
Topics: Acetates; Amines; Animals; Antimanic Agents; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Excitatory Postsynaptic Potentials; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Membrane Potentials; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Cord; Streptozocin; Synaptic Transmission; Tetrodotoxin | 2000 |
Antinociception and (R,S)-alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid antagonism by gabapentin in the rat spinal cord in vivo.
Topics: Acetates; Amines; Analgesics; Anesthesia; Animals; Bicuculline; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Iontophoresis; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 2000 |
Gabapentin-induced modulation of interictal epileptiform activity related to different vigilance levels.
Topics: Acetates; Adult; Amines; Arousal; Cyclohexanecarboxylic Acids; Electroencephalography; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Sleep | 2000 |
Modulation of K(+)-induced synaptosomal calcium influx by gabapentin.
Topics: Acetates; Amines; Animals; Calcium; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Male; Osmolar Concentration; Potassium; Rats; Rats, Sprague-Dawley; Synaptosomes | 2000 |
Opsoclonus-myoclonus syndrome: gabapentin as a new therapeutic proposal.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Paraneoplastic Syndromes, Nervous System | 2000 |
Effect of riluzole and gabapentin on cocaine- and methamphetamine-induced behavioral sensitization in mice.
Topics: Acetates; Amines; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Cyclohexanecarboxylic Acids; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Methamphetamine; Mice; Motor Activity; Riluzole; Time Factors | 2000 |
Single-shot, three-dimensional "non-echo" localization method for in vivo NMR spectroscopy.
Topics: Acetates; Animals; Aspartic Acid; Brain Chemistry; Calibration; Carbon Isotopes; Evaluation Studies as Topic; Formates; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Glycogen; Inositol; Lipids; Magnetic Resonance Spectroscopy; Male; Muscle, Skeletal; Ostreidae; Phantoms, Imaging; Protons; Radio Waves; Rats; Sensitivity and Specificity | 2000 |
Further evidence for the role of the alpha(2)delta subunit of voltage dependent calcium channels in models of neuropathic pain.
Topics: Acetates; Amines; Analgesics; Animals; Calcium Channels; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Male; Neuralgia; Rats; Rats, Sprague-Dawley; Streptozocin | 2000 |
Chronic cluster headache responding to gabapentin: a case report.
Topics: Acetates; Adult; Amines; Analgesics; Cluster Headache; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 2000 |
Pharmacological and immunohistochemical characterization of a mouse model of acute herpetic pain.
Topics: Acetates; Amines; Amitriptyline; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Diclofenac; Disease Models, Animal; Female; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Herpes Simplex; Herpesvirus 1, Human; Hyperalgesia; Mice; Mice, Inbred BALB C; Morphine; Neuralgia; Neurons, Afferent; Pain | 2000 |
Painful gynecomastia: an unusual toxicity of gabapentin?
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Gynecomastia; Humans; Male; Middle Aged; Pain | 2000 |
Gabapentin for chronic pain in spinal cord injury: a case report.
Topics: Acetates; Adult; Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Leg; Pain; Spinal Cord Injuries | 2000 |
Gabapentin, an adjuvant treatment for neuropathic pain in a cancer hospital.
Topics: Acetates; Amines; Analgesics; Cancer Care Facilities; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neoplasms; Pain | 2000 |
Gabapentin-induced mood changes with hypomanic features in adults.
Topics: Acetates; Adult; Affect; Amines; Anticonvulsants; Chlamydia Infections; Cyclohexanecarboxylic Acids; Encephalomyelitis; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Paresthesia; Social Behavior Disorders; Treatment Outcome | 2000 |
SUNCT syndrome responsive to gabapentin (Neurontin).
Topics: Acetates; Amines; Analgesics; Conjunctival Diseases; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Lacrimal Apparatus Diseases; Male; Middle Aged; Neuralgia; Nose Diseases; Retreatment; Sweating; Syndrome | 2000 |
[Treatment of chronic and neuropathic pain. Established amitriptyline and the new gabapentin].
Topics: Acetates; Amines; Amitriptyline; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Treatment Outcome | 2000 |
Effect of vigabatrin and gabapentin on phenytoin pharmacokinetics in the dog.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dogs; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Male; Phenytoin; Vigabatrin | 2000 |
Different effects of GABAergic anticonvulsants on 4-aminopyridine-induced spontaneous GABAergic hyperpolarizations of hippocampal pyramidal cells--implication for their potency in migraine therapy.
Topics: 4-Aminopyridine; Acetates; Amines; Analgesics; Animals; Anticonvulsants; Convulsants; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; Humans; Membrane Potentials; Migraine Disorders; Nipecotic Acids; Pyramidal Cells; Tiagabine; Time Factors; Valproic Acid; Vigabatrin | 2000 |
Fast isocratic high-performance liquid chromatographic assay method for the simultaneous determination of gabapentin and vigabatrin in human serum.
Topics: Acetates; Amines; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Vigabatrin | 2000 |
Anticonvulsant action and long-term effects of gabapentin in the immature brain.
Topics: Acetates; Amines; Animals; Anticonvulsants; Behavior, Animal; Brain; Convulsants; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Flurothyl; Gabapentin; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Kainic Acid; Male; Maze Learning; Memory; Rats; Rats, Sprague-Dawley; Seizures; Space Perception | 2001 |
Stimulus-dependent modulation of [(3)H]norepinephrine release from rat neocortical slices by gabapentin and pregabalin.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electric Stimulation; Gabapentin; gamma-Aminobutyric Acid; Male; Neocortex; Norepinephrine; Potassium; Pregabalin; Rats; Rats, Sprague-Dawley | 2000 |
[Clinical utilization of new anti-epileptic agents].
Topics: Acetates; Amines; Anemia, Aplastic; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Drug Tolerance; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Visual Fields | 2000 |
Gabapentin therapy for cocaine cravings.
Topics: Acetates; Adult; Amines; Anticonvulsants; Behavior, Addictive; Cocaine-Related Disorders; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Treatment Outcome | 2000 |
Antinociceptive effect of systemic gabapentin in mononeuropathic rats, depends on stimulus characteristics and level of test integration.
Topics: Acetates; Amines; Analgesics; Animals; Cold Temperature; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Male; Motor Activity; Nervous System Diseases; Nociceptors; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; Vocalization, Animal | 2000 |
Long-term retention rates of lamotrigine, gabapentin, and topiramate in chronic epilepsy.
Topics: Acetates; Adolescent; Adult; Age of Onset; Aged; Amines; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Patient Compliance; Patient Dropouts; Proportional Hazards Models; Survival Analysis; Topiramate; Triazines | 2000 |
Valproate and other anticonvulsants for psychiatric disorders.
Topics: Abnormalities, Drug-Induced; Acetates; Adult; Amines; Anti-Anxiety Agents; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cognition Disorders; Cyclohexanecarboxylic Acids; Dizziness; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fructose; Gabapentin; gamma-Aminobutyric Acid; Heart Defects, Congenital; Humans; Lamotrigine; Nausea; Obesity; Stevens-Johnson Syndrome; Topiramate; Triazines; Valproic Acid | 2000 |
Gamma-aminobutyric acid type B receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant gabapentin action.
Topics: Acetates; Amines; Amino Acid Sequence; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dimerization; Excitatory Postsynaptic Potentials; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA-B Receptor Agonists; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Molecular Sequence Data; Neurons; Oocytes; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Sequence Homology, Amino Acid; Xenopus laevis | 2001 |
Malignant appearing cachexia in an older patient with Bruns-Garland syndrome.
Topics: Acetates; Aged; Amines; Analgesics; Cachexia; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diagnosis, Differential; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Muscular Atrophy; Pain; Syndrome | 2000 |
Gabapentin or amitriptyline for painful diabetic neuropathy?
Topics: Acetates; Amines; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Family Practice; Gabapentin; gamma-Aminobutyric Acid; Humans; Treatment Outcome | 2000 |
Gabapentin antinociception in mice with acute herpetic pain induced by herpes simplex virus infection.
Topics: Acetates; Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Drug Tolerance; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Simplex; Herpesvirus 1, Human; Hyperalgesia; Mice; Mice, Inbred BALB C; Motor Activity; Naltrexone; Narcotic Antagonists; Pain | 2001 |
Rodent model of chronic central pain after spinal cord contusion injury and effects of gabapentin.
Topics: Acetates; Amines; Analgesics; Animals; Behavior, Animal; Chronic Disease; Contusions; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Male; Motor Activity; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reaction Time; Spinal Cord Injuries; Time Factors | 2000 |
Benzodiazepines and anticonvulsants for social phobia (social anxiety disorder).
Topics: Acetates; Alprazolam; Amines; Anticonvulsants; Benzodiazepines; Clinical Trials as Topic; Clonazepam; Cyclohexanecarboxylic Acids; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Phobic Disorders; Placebos; Pregabalin; Treatment Outcome; Valproic Acid | 2001 |
Evaluating the tolerability of the newer mood stabilizers.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Central Nervous System Diseases; Cyclohexanecarboxylic Acids; Drug Information Services; Fructose; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Diseases; Humans; Incidence; Lamotrigine; Mental Disorders; Neurotoxicity Syndromes; Topiramate; Triazines; Valproic Acid | 2001 |
The effects of GABA(B) agonists and gabapentin on mechanical hyperalgesia in models of neuropathic and inflammatory pain in the rat.
Topics: Acetates; Amines; Analgesics; Animals; Baclofen; Cyclohexanecarboxylic Acids; Electric Stimulation; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; In Vitro Techniques; Inflammation; Neuralgia; Rats; Rats, Wistar; Spinal Nerve Roots | 2001 |
Effect of glibenclamide in gabapentin antinociception.
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glyburide; Hypoglycemic Agents; Male; Morphine; Pain Measurement; Potassium Channels; Rats; Rats, Wistar | 2001 |
Gabapentin in phantom limb pain management in children and young adults: report of seven cases.
Topics: Acetates; Adult; Amines; Analgesics; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Palliative Care; Phantom Limb | 2001 |
Treatment of ciguatera poisoning with gabapentin.
Topics: Acetates; Adult; Amines; Animals; Anticonvulsants; Ciguatera Poisoning; Cyclohexanecarboxylic Acids; Female; Fishes, Poisonous; Gabapentin; gamma-Aminobutyric Acid; Humans; Poisoning | 2001 |
Gabapentin for misuse of homemade nicotine nasal spray.
Topics: Acetates; Administration, Intranasal; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Internet; Male; Middle Aged; Nebulizers and Vaporizers; Nicotine; Prescription Fees; Smoking Cessation; Tobacco Use Disorder | 2001 |
Gabapentin for the treatment of tinnitus: a case report.
Topics: Acetates; Amines; Amitriptyline; Analgesics; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Tinnitus | 2001 |
Function of leucine in excitatory neurotransmitter metabolism in the central nervous system.
Topics: Acetates; Amines; Animals; Astrocytes; Brain; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Isoenzymes; Ketoglutaric Acids; Leucine; Male; Mitochondria; Neurotransmitter Agents; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Transaminases | 2001 |
Adverse event monitoring in lamotrigine patients: a pharmacoepidemiologic study in the United Kingdom.
Topics: Acetates; Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Death, Sudden; Drug Eruptions; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Incidence; Lamotrigine; Male; Middle Aged; Neurotoxicity Syndromes; Pharmacoepidemiology; Product Surveillance, Postmarketing; Triazines; United Kingdom; Vigabatrin | 2001 |
Adjunctive gabapentin in treatment-resistant depression: a retrospective chart review.
Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Depressive Disorder; Dose-Response Relationship, Drug; Drug Resistance; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Recurrence; Retrospective Studies; Treatment Outcome | 2001 |
The effects of gabapentin on different ligand- and voltage-gated currents in isolated cortical neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetates; Amines; Animals; Anticonvulsants; Calcium Channel Agonists; Calcium Channels; Cerebral Cortex; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neurons; Potassium Channels; Pyramidal Cells; Rats; Rats, Wistar; Sodium Channels | 2001 |
Gabapentin-induced anorgasmia as a cause of noncompliance in a bipolar patient.
Topics: Acetates; Adult; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium; Male; Sexual Dysfunctions, Psychological | 2001 |
[Progressive encephalomyelitis with rigidity. Clinical and electrophysiological aspects].
Topics: Acetates; Aged; Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Electrophysiology; Encephalomyelitis; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Muscle Rigidity | 2001 |
Determination of the antiepileptics vigabatrin and gabapentin in dosage forms and biological fluids using Hantzsch reaction.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Fluorescent Dyes; Gabapentin; gamma-Aminobutyric Acid; Humans; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tablets; Vigabatrin | 2001 |
Postherpetic pain control with concomitant illness?
Topics: Acetates; Aged; Aged, 80 and over; Amines; Analgesics; Analgesics, Opioid; Biological Availability; Comorbidity; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Heart Failure; Herpes Zoster Oticus; Humans; Kidney Failure, Chronic; Male; Meperidine; Metabolic Clearance Rate; Patient Selection | 2001 |
Gabapentin quantification in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry. Application to bioequivalence study.
Topics: Acetates; Amines; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Spectrometry, Mass, Electrospray Ionization | 2001 |
ALS defeats gabapentin: reflections on another failed treatment.
Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Treatment Failure | 2001 |
Adjunctive gabapentin in patients with intellectual disability and bipolar spectrum disorders.
Topics: Acetates; Adult; Amines; Antimanic Agents; Bipolar Disorder; Comorbidity; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Male; Psychiatric Status Rating Scales; Psychotropic Drugs | 2001 |
Differences in gabapentin efficacy for cancer pain more apparent than real?
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neoplasms; Palliative Care | 2001 |
Gabapentin for treatment of behavioral and psychological symptoms of dementia.
Topics: Acetates; Aggression; Amines; Behavior; Cyclohexanecarboxylic Acids; Dementia, Vascular; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 2001 |
Differential effect of gabapentin on neuronal and muscle calcium currents.
Topics: Acetates; Amines; Animals; Calcium Channels; Cells, Cultured; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Heart; Membrane Potentials; Mice; Muscle, Skeletal; Myocardium; Neurons; Reverse Transcriptase Polymerase Chain Reaction | 2001 |
Calcium channel alpha(2)delta subunits-structure and Gabapentin binding.
Topics: Acetates; Amines; Amino Acid Sequence; Animals; Binding Sites; Calcium Channels; COS Cells; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Protein Conformation; Sequence Homology, Amino Acid; Transfection | 2001 |
Gabapentin use in benzodiazepine dependence and detoxification.
Topics: Acetates; Alprazolam; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Substance-Related Disorders; Treatment Outcome | 2001 |
[The effect of gabapentin and gabapentin-lactam on retinal ganglion cell survival. Situation after acute retinal ischemia in animal models].
Topics: Acetates; Amines; Animals; Anticonvulsants; Aza Compounds; Cell Survival; Convulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Ischemia; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Retinal Diseases; Retinal Ganglion Cells; Retinal Vessels; Spiro Compounds; Time Factors | 2001 |
Using gabapentin to treat failed back surgery syndrome caused by epidural fibrosis: A report of 2 cases.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Diskectomy; Epidural Space; Female; Fibrosis; Gabapentin; gamma-Aminobutyric Acid; Humans; Laminectomy; Low Back Pain; Lumbar Vertebrae; Magnetic Resonance Imaging; Pain Measurement; Postoperative Complications; Recovery of Function | 2001 |
Recurrent hypoventilation and respiratory failure during gabapentin therapy.
Topics: Acetates; Aged; Amines; Analgesics; Anti-Anxiety Agents; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypoventilation; Lung Diseases, Obstructive; Male; Peripheral Nervous System Diseases; Respiratory Insufficiency | 2001 |
Gabapentin and gabapentin monohydrate.
Topics: Acetates; Amines; Anticonvulsants; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydrogen Bonding; Molecular Structure; Water | 2001 |
Gabapentin treatment of the non-refractory bipolar spectrum: an open case series.
Topics: Acetates; Adult; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Depressive Disorder; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome | 2001 |
Behavioral effects of agents active at the gamma-aminobutyric acid receptor complex in the staircase paradigm.
Topics: Acetates; Adjuvants, Immunologic; Amines; Animals; Anti-Anxiety Agents; Anxiety; Azabicyclo Compounds; Behavior, Animal; Brain; Clonazepam; Cyclohexanecarboxylic Acids; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Exploratory Behavior; Flumazenil; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Mice; Mice, Inbred ICR; Motor Activity; Neurons; Piperazines; Receptors, GABA-A | 2001 |
Modulation of K+-evoked [3H]-noradrenaline release from rat and human brain slices by gabapentin: involvement of KATP channels.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Glyburide; Hippocampus; Humans; Hypoglycemic Agents; In Vitro Techniques; Male; Neocortex; Norepinephrine; Pinacidil; Potassium Channels; Potassium Chloride; Rats; Rats, Wistar; Retrospective Studies; Vasodilator Agents | 2001 |
Gabapentin for behavioral dyscontrol with mental retardation.
Topics: Acetates; Adult; Amines; Anticonvulsants; Antipsychotic Agents; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Mental Disorders; Psychomotor Agitation; Treatment Outcome | 2001 |
Three-month follow-up of shoulder-hand syndrome induced by phenobarbital and treated with gabapentin.
Topics: Acetaminophen; Acetates; Amines; Analgesics; Anticonvulsants; Arthralgia; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Metacarpophalangeal Joint; Middle Aged; Neuralgia; Pain; Phenobarbital; Reflex Sympathetic Dystrophy; Shoulder Pain; Treatment Outcome; Ulnar Nerve; Wrist Joint | 2001 |
Gabapentin for opiod-related myoclonus in cancer patients.
Topics: Acetates; Amines; Analgesics, Opioid; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Myoclonus; Neoplasms; Pain | 2001 |
Vincristine-induced allodynia in the rat.
Topics: Acetates; Amines; Analgesics; Animals; Antineoplastic Agents, Phytogenic; Body Weight; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Ion Channel Gating; Male; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Vincristine | 2001 |
Gabapentin actions on N-methyl-D-aspartate receptor channels are protein kinase C-dependent.
Topics: Acetates; Amines; Animals; Cell Separation; Cyclohexanecarboxylic Acids; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glycine; Immunohistochemistry; Male; N-Methylaspartate; Patch-Clamp Techniques; Protein Kinase C; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate | 2001 |
The anticonvulsant, antihyperalgesic agent gabapentin is an agonist at brain gamma-aminobutyric acid type B receptors negatively coupled to voltage-dependent calcium channels.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Baclofen; Calcium Channels; Calcium Signaling; Cyclohexanecarboxylic Acids; GABA Agonists; GABA-B Receptor Agonists; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Male; Mice; Mice, Transgenic; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 2001 |
Effects of Gabapentin and Topiramate in primary rat astrocyte cultures.
Topics: Acetates; Amines; Animals; Anticonvulsants; Astrocytes; Cell Survival; Cells, Cultured; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Glutamate-Ammonia Ligase; L-Lactate Dehydrogenase; Lipopolysaccharides; Nitric Oxide; Osmolar Concentration; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Topiramate | 2001 |
Oxcarbazepine in focal epilepsy and hepatic porphyria: a case report.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Comorbidity; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Enzyme Induction; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Germany; Humans; Liver; Male; Oxcarbazepine; Porphyria Cutanea Tarda; Porphyrias, Hepatic; Transaminases; Treatment Outcome | 2001 |
Effects of antiepileptic drugs on cognition.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cognition; Cognition Disorders; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Tiagabine; Topiramate; Triazines; Triazoles; Vigabatrin | 2001 |
The putative OP(4) antagonist, [Nphe(1)]nociceptin(1-13)NH(2), prevents the effects of nociceptin in neuropathic rats.
Topics: Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Morphine; Narcotic Antagonists; Narcotics; Neuralgia; Nociceptin; Nociceptin Receptor; Opioid Peptides; Pain Threshold; Peptide Fragments; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Sciatic Nerve; Spinal Cord | 2001 |
Effect of gabapentin and lamotrigine on mechanical allodynia-like behaviour in a rat model of trigeminal neuropathic pain.
Topics: Acetates; Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Lamotrigine; Ligation; Male; Nociceptors; Rats; Rats, Sprague-Dawley; Triazines; Trigeminal Neuralgia | 2001 |
Gabapentin inhibits the substance P-facilitated K(+)-evoked release of [(3)H]glutamate from rat caudial trigeminal nucleus slices.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neurokinin-1 Receptor Antagonists; Organ Culture Techniques; Piperidines; Potassium; Pregabalin; Rats; Rats, Inbred Strains; Stereoisomerism; Substance P; Trigeminal Nucleus, Spinal; Tritium | 2001 |
Charles Bonnet's syndrome: complete remission of complex visual hallucinations treated by gabapentin.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hallucinations; Humans; Syndrome; Visual Acuity | 2001 |
Anticonvulsant efficacy of gabapentin on kindling in the immature brain.
Topics: Acetates; Age Factors; Amines; Amygdala; Animals; Anticonvulsants; Behavior, Animal; Brain; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Female; Functional Laterality; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Kindling, Neurologic; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Seizures | 2001 |
Gabapentin as prophylaxis against steroid-induced mania.
Topics: Acetates; Amines; Anti-Inflammatory Agents; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Steroids | 2001 |
Gabapentin for the treatment of spasticity in patients with amyotrophic lateral sclerosis.
Topics: Acetates; Aged; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Motor Neuron Disease; Muscle Spasticity; Neurologic Examination; Treatment Outcome | 2001 |
Late-onset GM2 gangliosidosis presenting as burning dysesthesias.
Topics: Acetates; Adolescent; Amines; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Evoked Potentials, Somatosensory; Foot; Gabapentin; gamma-Aminobutyric Acid; Gangliosidoses, GM2; Humans; Male; Paresthesia; Sandhoff Disease; Treatment Outcome | 2001 |
Treatment of pain with gabapentin in a neonate.
Topics: Acetates; Amines; Analgesics; Arthrogryposis; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant, Newborn; Male; Pain; Pain Measurement; Treatment Outcome | 2001 |
Gabapentin interference with urine histidine as measured by the Beckman amino acid analyser.
Topics: Acetates; Adolescent; Adult; Amines; Amino Acid Metabolism, Inborn Errors; Anticonvulsants; Cyclohexanecarboxylic Acids; False Positive Reactions; Female; Gabapentin; gamma-Aminobutyric Acid; Histidine; Humans; Male | 2001 |
[Pharmacotherapy for neuropathic pain caused by injury to the afferent nerve fibers].
Topics: Acetates; Amines; Analgesics, Non-Narcotic; Cyclohexanecarboxylic Acids; Drug Approval; Gabapentin; gamma-Aminobutyric Acid; Humans; Netherlands; Neuralgia; Neurons, Afferent; Pain, Intractable | 2001 |
Gabapentin in painful HIV-related neuropathy: a report of 19 patients, preliminary observations.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; HIV Infections; Humans; Male; Middle Aged; Nervous System Diseases; Pain; Pain Measurement; Palliative Care; Sleep | 2001 |
Gabapentin-associated aggression.
Topics: Acetates; Adult; Aggression; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 2001 |
Gabapentin for pain control in cancer patients' wound dressing care.
Topics: Acetates; Amines; Analgesics; Bandages; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Mycosis Fungoides; Pain; Skin Neoplasms | 2001 |
Management strategies for refractory localization-related seizures.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Epilepsies, Partial; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Practice Patterns, Physicians'; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin | 2001 |
A pilot study of gabapentin as treatment for acquired nystagmus.
Topics: Acetates; Adult; Amines; Anticonvulsants; Brain Stem; Cerebrovascular Disorders; Cyclohexanecarboxylic Acids; Eye Movements; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Multiple Sclerosis; Nystagmus, Pathologic; Pilot Projects; Reflex, Vestibulo-Ocular; Vision Disorders; Visual Acuity | 1996 |
Assessing tinnitus and prospective tinnitus therapeutics using a psychophysical animal model.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Deafness; Diagnosis, Differential; Disease Models, Animal; Ear; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Male; Nipecotic Acids; Noise; Pitch Perception; Psychophysics; Rats; Rats, Long-Evans; Tiagabine; Tinnitus; Wounds and Injuries | 2001 |
Block by gabapentin of the facilitation of glutamate release from rat trigeminal nucleus following activation of protein kinase C or adenylyl cyclase.
Topics: Acetates; Adenylyl Cyclases; Amines; Analgesics; Animals; Colforsin; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Enzyme Activation; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Male; Potassium; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Trigeminal Nuclei; Tritium | 2001 |
Gabapentin neurotoxicity in a chronic haemodialysis patient.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Epilepsy, Absence; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Nervous System; Renal Dialysis | 2001 |
Memory improving actions of gabapentin in mice: possible involvement of central muscarinic cholinergic mechanism.
Topics: Acetates; Acetylcholine; Amines; Animals; Avoidance Learning; Brain; Cholinergic Antagonists; Cholinesterase Inhibitors; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Memory; Mice; Neural Inhibition; Receptors, Muscarinic | 2001 |
Quetiapine-related tardive dyskinesia.
Topics: Acetates; Adult; Amines; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Dibenzothiazepines; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium; Quetiapine Fumarate; Topiramate | 2001 |
Mucosal uptake of gabapentin (neurontin) vs. pregabalin in the small intestine.
Topics: Acetates; Alkaline Phosphatase; Amines; Amino Acids; Animals; Anticonvulsants; Biological Transport, Active; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Microvilli; Pregabalin; Rabbits; Rats; Sodium; Temperature | 2001 |
[Constrictive arachnoiditis after pantopaque myelography causing syringomyelia and paraparesis: case report].
Topics: Acetates; Amines; Analgesics; Arachnoid Cysts; Arachnoiditis; Constriction, Pathologic; Contrast Media; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Iophendylate; Male; Middle Aged; Myelography; Paraparesis; Syringomyelia; Time Factors | 2001 |
Effect of gabapentin-like compounds on development and maintenance of morphine-induced conditioned place preference.
Topics: Acetates; Amines; Analgesics, Opioid; Animals; Conditioning, Operant; Cyclohexanecarboxylic Acids; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Microdialysis; Morphine; Nucleus Accumbens; Pregabalin; Rats | 2001 |
Gabapentin and methylphenidate treatment of a preadolescent with attention deficit hyperactivity disorder and bipolar disorder.
Topics: Acetates; Amines; Antimanic Agents; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Central Nervous System Stimulants; Child; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Methylphenidate | 2001 |
ALS defeats gabapentin: reflections on another failed treatment.
Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Treatment Failure | 2001 |
Spectrofluorimetric determination of vigabatrin and gabapentin in urine and dosage forms through derivatization with fluorescamine.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dosage Forms; Fluorescamine; Gabapentin; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Molecular Structure; Reproducibility of Results; Spectrometry, Fluorescence; Vigabatrin | 2002 |
Changes in exploratory behavior as a measure of chronic central pain following spinal cord injury.
Topics: Acetates; Amines; Analgesics; Animals; Chronic Disease; Cyclohexanecarboxylic Acids; Exploratory Behavior; Gabapentin; gamma-Aminobutyric Acid; Habituation, Psychophysiologic; Male; Motor Activity; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries | 2001 |
Tissue-specific expression and gabapentin-binding properties of calcium channel alpha2delta subunit subtypes.
Topics: Acetates; Amines; Amino Acids; Animals; Anticonvulsants; Binding Sites; Calcium Channels; Cell Line; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Mice; Protein Binding; Protein Isoforms; Protein Structure, Secondary; Protein Subunits; Radioligand Assay; Tissue Distribution | 2001 |
Treating painful diabetic neuropathy with gabapentin.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Dose-Response Relationship, Drug; Drug Costs; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Pain Measurement; Patient Selection; Treatment Outcome | 2001 |
Gabapentin for clozapine-related seizures.
Topics: Acetates; Aged; Amines; Antimanic Agents; Antipsychotic Agents; Clozapine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Schizophrenia, Paranoid; Seizures | 2001 |
Gabapentin use in geriatric patients with depression and bipolar illness.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Antidepressive Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Depressive Disorder; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 2001 |
Gabapentin therapy for genitofemoral and ilioinguinal neuralgia.
Topics: Acetates; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Femoral Neuropathy; Gabapentin; gamma-Aminobutyric Acid; Hernia, Inguinal; Humans; Male; Middle Aged; Nerve Compression Syndromes; Neuralgia; Pain, Postoperative | 2001 |
Antinociceptive effect of the novel compound OT-7100 in a diabetic neuropathy model.
Topics: Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Disease Models, Animal; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hyperalgesia; Insulin; Male; Motor Neurons; Neural Conduction; Pain Threshold; Pyrazoles; Pyrimidines; Rats; Rats, Sprague-Dawley; Time Factors | 2001 |
A 28-year-old man addicted to cocaine.
Topics: Acetates; Adult; Amines; Brain; Cocaine-Related Disorders; Cost of Illness; Crack Cocaine; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Risk Factors | 2001 |
Estimation of aspartate synthesis in GABAergic neurons in mice by 13 C NMR spectroscopy.
Topics: 3-Mercaptopropionic Acid; Acetates; Amino Acids; Animals; Aspartic Acid; Carbon Radioisotopes; Cerebral Cortex; Energy Metabolism; GABA Agents; gamma-Aminobutyric Acid; Glucose; Glutamate Decarboxylase; Glutamine; Lactic Acid; Magnetic Resonance Spectroscopy; Mice; Nerve Tissue Proteins; Neurons; Synaptic Transmission | 2001 |
AUStralian study of titration to effect profile of safety (AUS-STEPS): high-dose gabapentin (neurontin) in partial seizures.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Australia; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electroencephalography; Epilepsies, Partial; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Prospective Studies; Quality of Life; Treatment Outcome | 2001 |
The acute effect of valproate on cerebral energy metabolism in mice.
Topics: Acetates; Adenosine Triphosphate; Animals; Anticonvulsants; Aspartic Acid; Brain; Citric Acid Cycle; Energy Metabolism; Female; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred ICR; Phosphocreatine; Valproic Acid | 2001 |
Role of specific aminotransferases in de novo glutamate synthesis and redox shuttling in the retina.
Topics: Acetates; Alanine Transaminase; Amines; Amino Acids, Branched-Chain; Animals; Antimetabolites; Aspartate Aminotransferases; Cyclohexanecarboxylic Acids; Cycloserine; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Mitochondria; Neuroglia; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Retina; Subcellular Fractions; Transaminases | 2001 |
Metabolic approach of absence seizures in a genetic model of absence epilepsy, the GAERS: study of the leucine-glutamate cycle.
Topics: Acetates; Amines; Amino Acids, Branched-Chain; Animals; Brain; Carbon Monoxide; Cells, Cultured; Cerebral Cortex; Cyclohexanecarboxylic Acids; Disease Models, Animal; Energy Metabolism; Epilepsy, Absence; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Keto Acids; L-Lactate Dehydrogenase; Leucine; Male; Neurons; Rats; Rats, Mutant Strains; Synaptic Transmission; Synaptic Vesicles; Transaminases | 2001 |
Tremor associated with benign IgM paraproteinaemic neuropathy successfully treated with gabapentin.
Topics: Acetates; Aged; Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hand; Humans; Immunoglobulin M; Paraproteinemias; Severity of Illness Index; Treatment Outcome; Tremor | 2001 |
Gabapentin is not a GABAB receptor agonist.
Topics: Acetates; Amines; Amino Acid Sequence; Animals; Anticonvulsants; Binding, Competitive; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Rats; Receptors, GABA-B | 2001 |
Gabapentin-related dyskinesia.
Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Anticonvulsants; Cyclohexanecarboxylic Acids; Dyskinesia, Drug-Induced; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 2001 |
Gabapentin-associated hepatotoxicity.
Topics: Acetates; Amines; Analgesics; Chemical and Drug Induced Liver Injury; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 2001 |
Gabapentin as add-on therapy in refractory partial epilepsy: a double-blind, placebo-controlled, parallel-group study. 1993.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; History, 20th Century; Humans; Placebos | 2001 |
Gabapentin inhibits high-threshold calcium channel currents in cultured rat dorsal root ganglion neurones.
Topics: Acetates; Amines; Animals; Anticonvulsants; Calcium; Calcium Channels; Cells, Cultured; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Membrane Potentials; Neurons, Afferent; Patch-Clamp Techniques; Rats; Rats, Wistar | 2002 |
[Diabetic neuropathies].
Topics: Acetates; Amines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbamazepine; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Double-Blind Method; Electrophysiology; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperglycemia; Immunoglobulins, Intravenous; Linoleic Acid; Pain; Prognosis | 2001 |
Gabapentin-induced worsening of neuropsychiatric symptoms in dementia with lewy bodies: case reports.
Topics: Acetates; Aged; Amines; Cyclohexanecarboxylic Acids; Dementia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lewy Bodies; Male; Mental Health; Nervous System | 2002 |
Inhibition of neuronal Ca(2+) influx by gabapentin and pregabalin in the human neocortex.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Calcium; Calcium Channel Blockers; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Immunoblotting; Male; Middle Aged; Neocortex; Neurons; Norepinephrine; omega-Agatoxin IVA; Potassium; Pregabalin; Quinoxalines; Receptors, AMPA; Synaptosomes | 2002 |
Gabapentin treatment of multiple piloleiomyoma-related pain.
Topics: Acetates; Administration, Oral; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Leiomyomatosis; Middle Aged; Pain; Skin Neoplasms | 2002 |
[Gabapentin in the treatment of chronic intractable pain].
Topics: Acetates; Amines; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Carbamazepine; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Pain, Intractable; Placebos; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Time Factors; Triazines | 2002 |
Treatment of alcohol withdrawal with gabapentin.
Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Ethanol; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Mood Disorders; Substance Withdrawal Syndrome | 2002 |
Vulvodynia--new and more effective approaches to therapy.
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Treatment Outcome; Vulvar Diseases | 2002 |
Hyperhidrosis in pediatric spinal cord injury: a case report and gabapentin therapy.
Topics: Acetates; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hematoma, Epidural, Cranial; Humans; Hyperhidrosis; Spinal Cord Injuries | 2002 |
A combination of gabapentin and morphine mediates enhanced inhibitory effects on dorsal horn neuronal responses in a rat model of neuropathy.
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; Electrophysiology; Gabapentin; gamma-Aminobutyric Acid; Ligation; Male; Morphine; Nerve Fibers; Pain; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Cord Diseases; Spinal Nerves | 2002 |
Pregnancy registries in epilepsy.
Topics: Abnormalities, Drug-Induced; Acetates; Amines; Anticonvulsants; Australia; Cross-Cultural Comparison; Cyclohexanecarboxylic Acids; Data Collection; Databases as Topic; Epilepsy; Europe; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; India; Infant, Newborn; International Cooperation; Lamotrigine; Pregnancy; Pregnancy Complications; Product Surveillance, Postmarketing; Registries; Severity of Illness Index; Triazines; United Kingdom; Vigabatrin | 2001 |
Gabapentin for hot flashes in prostate cancer.
Topics: Acetates; Aged; Amines; Androgen Antagonists; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Hot Flashes; Humans; Male; Prostatic Neoplasms | 2002 |
Gabapentin-mediated inhibition of voltage-activated Ca2+ channel currents in cultured sensory neurones is dependent on culture conditions and channel subunit expression.
Topics: Acetates; Amines; Animals; Anticonvulsants; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Coculture Techniques; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Ion Channel Gating; Membrane Potentials; Neural Inhibition; Neurons, Afferent; Patch-Clamp Techniques; Rats; Rats, Wistar | 2002 |
Gabapentin in migraine prophylaxis: is it effective and well tolerated?
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Migraine Disorders | 2002 |
The interaction between gabapentin and amitriptyline in the rat formalin test after systemic administration.
Topics: Acetates; Amines; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley | 2002 |
[Gabapentin treatment of glossopharyngeal neuralgia with cardiac syncope].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glossopharyngeal Nerve Diseases; Humans; Male; Middle Aged; Syncope | 2002 |
[Adult GM2 gangliosidosis: improvement of ataxia with GABAergic drugs].
Topics: Acetates; Adult; Amines; Ataxia; beta-N-Acetylhexosaminidases; Cerebellum; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Gangliosidoses, GM2; Humans; Male; Myokymia; Nipecotic Acids; Tiagabine; Tomography, X-Ray Computed | 2002 |
The effect of intrathecal gabapentin on mechanical and thermal hyperalgesia in neuropathic rats induced by spinal nerve ligation.
Topics: Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Ligation; Male; Rats; Rats, Sprague-Dawley; Spinal Nerves; Time Factors | 2002 |
Case reports - reversal of sensory deficit associated with pain relief after treatment with gabapentin.
Topics: Acetates; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Somatosensory Disorders | 2002 |
Comment on Rice ASC, Maton S, the Postherpetic Neuralgia Study Group (UK), gabapentin in postherpetic neuralgia: a randomized, double blind, placebo-controlled study.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia; Randomized Controlled Trials as Topic | 2002 |
Comment on Rice ASC, Maton S, the Postherpetic Neuralgia Study Group (UK), gabapentin in postherpetic neuralgia: a randomized, double blind, placebo-controlled study.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia; Randomized Controlled Trials as Topic | 2002 |
[Toxocara canis meningoradiculitis].
Topics: Acetates; Adrenal Cortex Hormones; Aged; Amines; Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Antibodies, Helminth; Anticonvulsants; Cerebrospinal Fluid Proteins; Chest Pain; Cyclohexanecarboxylic Acids; Eosinophilia; Gabapentin; gamma-Aminobutyric Acid; Glucose; Humans; Hyperesthesia; Immunoglobulin E; Magnetic Resonance Imaging; Male; Meningitis; Radiculopathy; Steroids; Toxocara canis; Toxocariasis; Tramadol | 2002 |
Effects of analgesics on delayed postherpetic pain in mice.
Topics: Acetates; Acute Disease; Acyclovir; Amines; Analgesics; Analgesics, Opioid; Animals; Antiviral Agents; Behavior, Animal; Cyclohexanecarboxylic Acids; DNA, Viral; Female; Gabapentin; gamma-Aminobutyric Acid; Herpesviridae Infections; Herpesvirus 1, Human; Mexiletine; Mice; Mice, Inbred BALB C; Morphine; Pain; Pain Measurement; Physical Stimulation | 2002 |
Gabapentin potentiates N-methyl-D-aspartate receptor mediated currents in rat GABAergic dorsal horn neurons.
Topics: Acetates; Afferent Pathways; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Fluorescent Dyes; Gabapentin; gamma-Aminobutyric Acid; Immunohistochemistry; Inflammation; Ion Channels; Isoquinolines; Lysine; Membrane Potentials; Nociceptors; Pain; Patch-Clamp Techniques; Posterior Horn Cells; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2002 |
Effect of some antiepileptic drugs on brain histaminergic systems in the rat.
Topics: Acetates; Amines; Animals; Anticonvulsants; Brain Chemistry; Cyclohexanecarboxylic Acids; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Histamine; Methylhistamines; Phenytoin; Rats; Rats, Wistar | 2002 |
The anticonvulsant gabapentin (neurontin) does not act through gamma-aminobutyric acid-B receptors.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cells, Cultured; Cyclohexanecarboxylic Acids; Dogs; Esophagogastric Junction; Gabapentin; gamma-Aminobutyric Acid; Humans; Models, Animal; Oocytes; Rats; Receptors, GABA-B; Recombinant Proteins; Synaptic Membranes; Xenopus laevis | 2002 |
Doctor sues company over unethical marketing.
Topics: Acetates; Advertising; Amines; Anticonvulsants; Conflict of Interest; Cyclohexanecarboxylic Acids; Drug Industry; Ethics, Professional; Gabapentin; gamma-Aminobutyric Acid; Humans; United States | 2002 |
Treatment of spasticity.
Topics: Acetates; Amines; Aminopyridines; Baclofen; Benzodiazepines; Botulinum Toxins, Type A; Clonidine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Memantine; Muscle Spasticity; Paralysis; Rhizotomy | 2002 |
Gabapentin for neuropathic pain following spinal cord injury.
Topics: Acetates; Acute Disease; Adolescent; Adult; Aged; Amines; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Paraplegia; Quadriplegia; Reproducibility of Results; Retrospective Studies; Sensitivity and Specificity; Spinal Cord Injuries; Withholding Treatment | 2002 |
Gabapentin (neuronetin) in the treatment of SUNCT syndrome.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Headache Disorders; Humans; Middle Aged; Pain | 2002 |
Gabapentin in complicated school refusal.
Topics: Acetates; Adolescent; Amines; Comorbidity; Cyclohexanecarboxylic Acids; Cyclohexanols; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydroxyzine; Male; Mental Disorders; Phobic Disorders; Treatment Outcome; Venlafaxine Hydrochloride | 2002 |
Gabapentin: resistant neuropathic pain and malignancy.
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Resistance; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuralgia; Rhabdomyosarcoma | 2001 |
Experimental conditions for the continuous subcutaneous infusion of four central analgesics in rats.
Topics: Acetates; Amines; Analgesics; Anesthetics, Dissociative; Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Chronic Disease; Convulsants; Cyclohexanecarboxylic Acids; Drug Stability; Gabapentin; gamma-Aminobutyric Acid; Hypothermia; Imipramine; Infusion Pumps, Implantable; Ketamine; Male; Morphine; Pain; Pain Measurement; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Solubility; Tetrabenazine | 2002 |
Block of L-type Ca2+ current by beauvericin, a toxic cyclopeptide, in the NG108-15 neuronal cell line.
Topics: Acetates; Action Potentials; Amines; Animals; Anti-Bacterial Agents; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cyclohexanecarboxylic Acids; Depsipeptides; Electrophysiology; Gabapentin; gamma-Aminobutyric Acid; Glioma; Kinetics; Mice; Neuroblastoma; Neurons; omega-Conotoxin GVIA; Peptides; Potassium; Rats; Tumor Cells, Cultured | 2002 |
Facial pain following sinonasal surgery or facial trauma.
Topics: Acetates; Adult; Aged; Amines; Amitriptyline; Analgesics, Non-Narcotic; Carbamazepine; Cyclohexanecarboxylic Acids; Endoscopy; Facial Injuries; Facial Pain; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Paranasal Sinuses; Retrospective Studies | 2002 |
Gabapentin and vigabatrin increase GABA in the human neocortical slice.
Topics: Acetates; Adolescent; Adult; Amines; Animals; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Male; Middle Aged; Neocortex; Rats; Rats, Sprague-Dawley; Vigabatrin | 2002 |
Gabapentin treatment of impulsive-aggressive behaviour.
Topics: Acetates; Adult; Aggression; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Impulsive Behavior; Male; Psychiatric Status Rating Scales | 2002 |
Gabapentin-induced anorgasmia in women.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Libido; Sexual Dysfunctions, Psychological | 2002 |
Gabapentin toxicity requiring intubation in a patient receiving long-term hemodialysis.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Overdose; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypoxia; Intubation; Kidney Failure, Chronic; Middle Aged; Renal Dialysis | 2002 |
Recurrent complex partial status epilepticus associated with tiagabine rechallenge.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Humans; Lorazepam; Male; Meningoencephalitis; Nipecotic Acids; Status Epilepticus; Tiagabine; Treatment Outcome | 2002 |
Strictly unilateral headache reminiscent of hemicrania continua resistant to indomethacin but responsive to gabapentin.
Topics: Acetates; Adult; Amines; Anti-Inflammatory Agents, Non-Steroidal; Blepharoptosis; Cyclohexanecarboxylic Acids; Diagnostic Imaging; Drug Resistance; Gabapentin; gamma-Aminobutyric Acid; Humans; Indomethacin; Male; Migraine Disorders; Neurologic Examination; Vomiting | 2002 |
Preferential action of gabapentin and pregabalin at P/Q-type voltage-sensitive calcium channels: inhibition of K+-evoked [3H]-norepinephrine release from rat neocortical slices.
Topics: Acetates; Amines; Animals; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Neocortex; Norepinephrine; Potassium; Pregabalin; Rats; Rats, Sprague-Dawley; Tritium | 2002 |
[Psychomotor slowness of a mentally retarded woman].
Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Clobazam; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypothyroidism; Persons with Mental Disabilities; Psychomotor Disorders; Thyrotropin; Thyroxine | 2001 |
Neurotransmitter mechanisms in gabapentin antinociception.
Topics: Acetates; Amines; Analgesics; Analysis of Variance; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Injections, Subcutaneous; Male; Neurotransmitter Agents; Pain Measurement; Rats; Rats, Wistar; Receptors, Neurotransmitter | 2002 |
Gabapentin suppresses cutaneous hyperalgesia following heat-capsaicin sensitization.
Topics: Acetates; Adult; Amines; Analgesics; Capsaicin; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Humans; Hyperalgesia; Male | 2002 |
Changes in expression of voltage-dependent ion channel subunits in dorsal root ganglia of rats with radicular injury and pain.
Topics: Acetates; Amines; Analgesics; Animals; Behavior, Animal; Calcium Channels; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Gene Expression Regulation; Male; Pain; Pain Measurement; Protein Subunits; Radiculopathy; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Channels | 2002 |
Gabapentin for coeliac plexus pain.
Topics: Acetates; Aged; Amines; Analgesics; Celiac Plexus; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neoplasm Invasiveness; Nervous System Neoplasms; Pain; Pancreatic Neoplasms | 2002 |
Massive gabapentin and presumptive quetiapine overdose.
Topics: Acetates; Amines; Anti-Anxiety Agents; Antipsychotic Agents; Coma; Cyclohexanecarboxylic Acids; Dibenzothiazepines; Drug Overdose; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypotension; Middle Aged; Quetiapine Fumarate; Respiration, Artificial; Respiratory Insufficiency; Suicide, Attempted | 2002 |
Gabapentin treatment of glossopharyngeal neuralgia: a follow-up of four years of a single case.
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Glossopharyngeal Nerve; Glossopharyngeal Nerve Diseases; Humans; Middle Aged; Tramadol; Treatment Outcome | 2002 |
Gabapentin and pregabalin suppress tactile allodynia and potentiate spinal cord stimulation in a model of neuropathy.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Electric Stimulation; Electrophysiology; Gabapentin; gamma-Aminobutyric Acid; Injections; Ischemia; Male; Mononeuropathies; Pain; Pain Management; Posterior Horn Cells; Pregabalin; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord; Touch | 2002 |
Gabapentin in the treatment of SUNCT syndrome.
Topics: Acetates; Amines; Analgesics; Conjunctiva; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Headache Disorders; Humans; Middle Aged; Neuralgia; Syndrome; Tears | 2002 |
SUNCT responsive to gabapentin.
Topics: Acetates; Adult; Amines; Analgesics; Conjunctiva; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Orbit; Pain; Syndrome; Tears | 2002 |
Gabapentin inhibits presynaptic Ca(2+) influx and synaptic transmission in rat hippocampus and neocortex.
Topics: Acetates; Amines; Animals; Anticonvulsants; Calcium; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Electrophysiology; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Ion Channel Gating; Male; Neocortex; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Presynaptic; Synaptic Transmission; Synaptosomes | 2002 |
Central post-stroke pain syndrome: yet another use for gabapentin?
Topics: Acetates; Activities of Daily Living; Administration, Oral; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Stroke; Syndrome; Time Factors; Treatment Outcome | 2002 |
Dissociation of charge movement from calcium release and calcium current in skeletal myotubes by gabapentin.
Topics: Acetates; Amines; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Cyclohexanecarboxylic Acids; Electric Stimulation; Gabapentin; gamma-Aminobutyric Acid; Ion Transport; Membrane Potentials; Mice; Muscle, Skeletal; Nifedipine; Patch-Clamp Techniques; Protein Subunits | 2002 |
Molecular cloning and characterization of the human voltage-gated calcium channel alpha(2)delta-4 subunit.
Topics: Acetates; Alternative Splicing; Amines; Amino Acid Sequence; Base Sequence; Biological Transport; Blotting, Northern; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Chromosome Mapping; Chromosomes, Human, Pair 12; Cloning, Molecular; Cyclohexanecarboxylic Acids; Exons; Gabapentin; gamma-Aminobutyric Acid; Humans; Immunohistochemistry; Molecular Sequence Data; Protein Subunits; Sequence Homology, Amino Acid; Tissue Distribution | 2002 |
[A relief from neural pain--gabapentin helped against hip ache in a girl with cerebral palsy].
Topics: Acetates; Adolescent; Amines; Analgesics; Arthralgia; Cerebral Palsy; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hip Joint; Humans; Muscle Spasticity; Treatment Outcome | 2001 |
Comparison of antiepileptic drugs tiagabine, lamotrigine, and gabapentin in mouse models of acute, prolonged, and chronic nociception.
Topics: Acetates; Acute Disease; Adrenergic alpha-Agonists; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Dynorphins; Formaldehyde; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Injections, Intraperitoneal; Injections, Spinal; Lamotrigine; Male; Mice; Mice, Inbred ICR; Nipecotic Acids; Pain; Pain Measurement; Reaction Time; Tiagabine; Triazines | 2002 |
The 'number needed to treat' with levetiracetam (LEV): comparison with the other new antiepileptic drugs (AEDs).
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2002 |
Re: Lasso-de-la-Vega et al. gabapentin as a probable cause of hepatotoxicity and eosinophilia.
Topics: Acetates; Amines; Analgesics; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Ciprofloxacin; Cyclohexanecarboxylic Acids; Eosinophilia; Gabapentin; gamma-Aminobutyric Acid; Humans; Liver Function Tests; Male; Middle Aged | 2002 |
Gabapentin and PTSD.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Stress Disorders, Post-Traumatic; Topiramate | 2002 |
Effect of gabapentin on the anticonvulsant activity of antiepileptic drugs against electroconvulsions in mice: an isobolographic analysis.
Topics: Acetates; Amines; Animals; Anticonvulsants; Behavior, Animal; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Electroshock; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Kindling, Neurologic; Male; Memory; Mice; Motor Activity; Random Allocation; Seizures | 2002 |
A postmarketing surveillance study of gabapentin as add-on therapy for 3,100 patients in England.
Topics: Acetates; Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Aged, 80 and over; Amines; Anticonvulsants; Cause of Death; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug Therapy, Combination; England; Epilepsy; Exanthema; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Male; Middle Aged; Product Surveillance, Postmarketing; Sleep Stages; Weight Gain | 2002 |
Is gabapentin a "Broad-spectrum" analgesic?
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Neuronal Plasticity; Pain | 2002 |
Gabapentin induced cholestasis.
Topics: Acetates; Amines; Anticonvulsants; Cholestasis; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Humans; Liver Function Tests; Male; Middle Aged | 2002 |
Long-term regulation of voltage-gated Ca(2+) channels by gabapentin.
Topics: Acetates; Amines; Animals; Anticonvulsants; Brain; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Oocytes; Protein Conformation; Rabbits; Rats; Recombinant Proteins; Seizures; Xenopus laevis | 2002 |
High-performance liquid chromatographic method for the determination of gabapentin in human plasma.
Topics: Acetates; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Therapeutic Equivalency | 2002 |
Down-regulation of N-type voltage-activated Ca2+ channels by gabapentin.
Topics: Acetates; Action Potentials; Amines; Amino Acid Transport System L; Animals; Anticonvulsants; Brain; Calcium; Calcium Channels, N-Type; Calcium Signaling; Cell Membrane; Cyclohexanecarboxylic Acids; Down-Regulation; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Neural Inhibition; Neurons; omega-Conotoxins; Rats; Tumor Cells, Cultured | 2002 |
Treating hot flashes with drugs: an update.
Topics: Acetates; Amines; Anticonvulsants; Antidepressive Agents, Second-Generation; Antihypertensive Agents; Clonidine; Cyclohexanecarboxylic Acids; Cyclohexanols; Female; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Venlafaxine Hydrochloride | 2002 |
Gabapentin -- a promising treatment in glossodynia.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Glossalgia; Humans; Middle Aged; Psychophysiologic Disorders | 2002 |
Gabapentin and the neurokinin(1) receptor antagonist CI-1021 act synergistically in two rat models of neuropathic pain.
Topics: Acetates; Amines; Animals; Benzofurans; Carbamates; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Neurokinin-1 Receptor Antagonists; Pain; Pain Measurement; Peripheral Nervous System Diseases; Piperidines; Rats; Rats, Sprague-Dawley | 2002 |
Anti-allodynic action of the tormentic acid, a triterpene isolated from plant, against neuropathic and inflammatory persistent pain in mice.
Topics: Acetates; Amines; Analgesics; Animals; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; Inflammation; Ligation; Male; Mice; Motor Activity; Pain; Peripheral Nervous System Diseases; Phytotherapy; Plant Bark; Plant Extracts; Sciatic Nerve; Time Factors; Touch; Triterpenes | 2002 |
Gabapentin and pregabalin can interact synergistically with naproxen to produce antihyperalgesia.
Topics: Acetates; Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Calcium Channels; Cyclohexanecarboxylic Acids; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Naproxen; Pregabalin; Rats; Rats, Sprague-Dawley | 2002 |
Gabapentin for the treatment of familial erythromelalgia pain.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Erythromelalgia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged | 2002 |
Cavernous angioma in the brachium pontis presenting with trigeminal neuralgia: a case report.
Topics: Acetates; Amines; Analgesics; Central Nervous System Vascular Malformations; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hemangioma, Cavernous; Humans; Magnetic Resonance Imaging; Male; Mesencephalon; Middle Aged; Pain; Radiography; Trigeminal Neuralgia | 2002 |
[Edematous syndrome and alithiasic cholecystitis induced by gabapentin].
Topics: Acetates; Adult; Amines; Anticonvulsants; Cholecystitis; Cyclohexanecarboxylic Acids; Edema; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Syndrome | 2002 |
Large-amplitude 5-HT1A receptor activation: a new mechanism of profound, central analgesia.
Topics: Acetates; Adrenergic Uptake Inhibitors; Amines; Aminopyridines; Analgesia; Analgesics; Animals; Cells, Cultured; CHO Cells; Cricetinae; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Synergism; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Hyperalgesia; Imipramine; Ketamine; Male; Morphine; Pain; Pain Measurement; Pain Threshold; Piperidines; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Time Factors; Transfection | 2002 |
Combined pharmacologic and surgical approach to acquired nystagmus due to multiple sclerosis.
Topics: Acetates; Adult; Amines; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Diplopia; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Head Movements; Humans; Male; Multiple Sclerosis; Nystagmus, Pathologic; Oculomotor Muscles; Ophthalmologic Surgical Procedures; Posture; Visual Acuity | 2002 |
Gabapentin-induced bullous pemphigoid.
Topics: Acetates; Amines; Anticonvulsants; Azathioprine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pemphigoid, Bullous; Prednisolone; Treatment Outcome | 2002 |
Injury type-specific calcium channel alpha 2 delta-1 subunit up-regulation in rat neuropathic pain models correlates with antiallodynic effects of gabapentin.
Topics: Acetates; Amines; Animals; Calcium Channels; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Humans; Ligation; Male; Pain; Pain Measurement; Protein Subunits; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Spinal Cord; Up-Regulation | 2002 |
Determination of gabapentin in plasma by liquid chromatography with fluorescence detection after solid-phase extraction with a C18 column.
Topics: Acetates; Amines; Anticonvulsants; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Spectrometry, Fluorescence | 2002 |
Effectiveness of adjunctive gabapentin in resistant bipolar disorder: is it due to anxious-alcohol abuse comorbidity?
Topics: Acetates; Adult; Aged; Alcoholism; Amines; Anticonvulsants; Antimanic Agents; Anxiety Disorders; Bipolar Disorder; Comorbidity; Cyclohexanecarboxylic Acids; Drug Resistance; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Sampling Studies; Treatment Outcome | 2002 |
Improvement of acquired pendular nystagmus by gabapentin: case report.
Topics: Acetates; Administration, Oral; Amines; Baclofen; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Multiple Sclerosis; Nystagmus, Pathologic; Treatment Outcome | 2001 |
Modulation of the in vivo effects of gabapentin by vigabatrin and SKF89976A.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dentate Gyrus; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Evoked Potentials; Gabapentin; gamma-Aminobutyric Acid; Male; Neural Inhibition; Nipecotic Acids; Rats; Rats, Sprague-Dawley; Reaction Time; Vigabatrin | 2002 |
Gabapentin in painful ophthalmoplegia.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Tolosa-Hunt Syndrome | 2002 |
Gabapentin increases slow-wave sleep in normal adults.
Topics: Acetates; Adult; Amines; Anticonvulsants; Arousal; Cyclohexanecarboxylic Acids; Dizziness; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Polysomnography; Reaction Time; Sleep Stages; Sleep, REM; Wakefulness | 2002 |
Lumbar spinal cord stimulation for cervical-originated central pain: a case report.
Topics: Acetates; Amines; Antidepressive Agents, Tricyclic; Cervical Vertebrae; Cyclohexanecarboxylic Acids; Electric Stimulation Therapy; Electrodes, Implanted; Female; Foramen Magnum; Gabapentin; gamma-Aminobutyric Acid; Humans; Laminectomy; Lidocaine; Lumbosacral Region; Meningeal Neoplasms; Meningioma; Middle Aged; Pain; Pain Management; Pain, Intractable; Pain, Postoperative | 2002 |
Self-injurious behavior in children and adolescents with spinal cord injuries.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Occupational Therapy; Paresthesia; Self Mutilation; Spinal Cord Injuries | 2002 |
Nifedipine potentiates gabapentin antinociception in rats.
Topics: Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Male; Nifedipine; Pain Measurement; Rats; Rats, Wistar | 2002 |
Hyperhidrosis in social anxiety disorder.
Topics: Acetates; Adult; Amines; Calcium Channel Blockers; Clinical Trials as Topic; Clonazepam; Cognitive Behavioral Therapy; Cyclohexanecarboxylic Acids; Female; Fluoxetine; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperhidrosis; Male; Phobic Disorders; Prognosis; Retrospective Studies; Selective Serotonin Reuptake Inhibitors | 2002 |
Flumazenil and dialysis for gabapentin-induced coma.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Analgesics; Antidotes; Coma; Cyclohexanecarboxylic Acids; Flumazenil; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Phantom Limb; Renal Dialysis | 2003 |
Gabapentin-- actions on adult superficial dorsal horn neurons.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Excitatory Postsynaptic Potentials; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Male; N-Methylaspartate; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 2002 |
Gabapentin withdrawal presenting as status epilepticus.
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Low Back Pain; Male; Spine; Status Epilepticus; Substance Withdrawal Syndrome | 2002 |
Photochemical cleavage and release of carboxylic acids from alpha-keto amides.
Topics: Acetates; Amides; Carboxylic Acids; gamma-Aminobutyric Acid; Ketones; Molecular Structure; Photolysis; Spectroscopy, Fourier Transform Infrared | 2003 |
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Death; Cells, Cultured; Chlordiazepoxide; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hippocampus; Hypoxia; Ischemia; Lamotrigine; Levetiracetam; Midazolam; Neurons; Neuroprotective Agents; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Rats; Rats, Wistar; Tiagabine; Triazines; Valproic Acid | 2003 |
[Neuropathic pain. Often mishandled for years].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Treatment Outcome | 2002 |
Coadministration of gabapentin or MK-801 with lamotrigine slows tolerance to its anticonvulsant effects on kindled seizures.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dizocilpine Maleate; Drug Therapy, Combination; Drug Tolerance; Gabapentin; gamma-Aminobutyric Acid; Kindling, Neurologic; Lamotrigine; Male; Rats; Rats, Sprague-Dawley; Seizures; Triazines | 2003 |
Plasma gabapentin concentrations in children with epilepsy: influence of age, relationship with dosage, and preliminary observations on correlation with clinical response.
Topics: Acetates; Adolescent; Adult; Age Factors; Amines; Analysis of Variance; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Statistics, Nonparametric | 2003 |
Gabapentin-induced paradoxical exacerbation of psychosis in a patient with schizophrenia.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Psychoses, Substance-Induced; Schizophrenia; Severity of Illness Index | 2002 |
Gabapentin increases the hyperpolarization-activated cation current Ih in rat CA1 pyramidal cells.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cations; Cyclic AMP; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsies, Partial; Epilepsy, Temporal Lobe; Female; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Ion Channels; Male; Membrane Potentials; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar | 2003 |
Colorimetric determination of gabapentin in pharmaceutical formulation.
Topics: Acetates; Amines; Anticonvulsants; Benzoquinones; Buffers; Capsules; Colorimetry; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Indicators and Reagents; Ninhydrin; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet | 2003 |
Gabapentin markedly reduces acetic acid-induced visceral nociception.
Topics: Acetates; Amines; Analgesics; Animals; Calcium; Cyclohexanecarboxylic Acids; Excitatory Amino Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Pain; Rats; Rats, Sprague-Dawley; Viscera | 2003 |
[Recognizing the "neck-tongue" syndrome].
Topics: Acetates; Amines; Analgesics; Analgesics, Non-Narcotic; Arthritis; Cervical Vertebrae; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypesthesia; Hypoglossal Nerve; Ibuprofen; Lingual Nerve; Middle Aged; Neck Pain; Pain; Spinal Diseases; Syndrome; Tongue; Tongue Diseases | 2003 |
Gabapentin therapy for amyotrophic lateral sclerosis: lack of improvement in neuronal integrity shown by MR spectroscopy.
Topics: Acetates; Aged; Amines; Amyotrophic Lateral Sclerosis; Aspartic Acid; Cell Survival; Creatine; Cyclohexanecarboxylic Acids; Energy Metabolism; Excitatory Amino Acid Antagonists; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Motor Cortex; Parietal Lobe; Reference Values; Treatment Outcome | 2003 |
The importance of the complete history in the discovery of a potential suicide: a case report.
Topics: Acetates; Amines; Analgesics, Opioid; Anti-Anxiety Agents; Anti-Bacterial Agents; Cyclohexanecarboxylic Acids; Depression; Diabetes Complications; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Leg Ulcer; Lower Extremity; Middle Aged; Morphine; Pain, Intractable; Peripheral Vascular Diseases; Sepsis; Suicide, Attempted | 2003 |
Astrocyte metabolism is disturbed in the early development of experimental hydrocephalus.
Topics: Acetates; Animals; Astrocytes; Biomarkers; Brain Stem; Carbon Isotopes; Disease Models, Animal; Disease Progression; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Hydrocephalus; Kaolin; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Neurotransmitter Agents; Predictive Value of Tests; Rats; Rats, Sprague-Dawley; Taurine; Telencephalon | 2003 |
Anorgasmia and withdrawal syndrome in a woman taking gabapentin.
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mood Disorders; Sexual Dysfunctions, Psychological; Substance Withdrawal Syndrome | 2003 |
Hot flashes. A closer look at causes and remedies.
Topics: Acetates; Amines; Antidepressive Agents; Body Temperature Regulation; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Hypothalamus; Norpregnenes | 2003 |
[Diagnose Sudeck's disease in good time and save your patient from martyrdom].
Topics: Acetates; Adrenergic Agents; Amines; Analgesics; Analgesics, Opioid; Antipsychotic Agents; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Guanethidine; Humans; Physical Therapy Modalities; Reflex Sympathetic Dystrophy; Sympatholytics; Time Factors; World Health Organization | 2003 |
Suppression by gabapentin of pain-related mechano-responses in mice given orthotopic tumor inoculation.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Mechanoreceptors; Mechanotransduction, Cellular; Melanoma; Mice; Mice, Inbred C57BL; Pain; Pain Measurement; Physical Stimulation; Xenograft Model Antitumor Assays | 2003 |
Gabbing about gabapentin.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Approval; Gabapentin; gamma-Aminobutyric Acid; Humans; Legislation, Drug; Neuralgia; United States; United States Food and Drug Administration | 2003 |
Spinal gabapentin and antinociception: mechanisms of action.
Topics: Acetates; Adrenergic alpha-Antagonists; Adrenergic Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amines; Analgesics; Animals; Atropine; Cyclohexanecarboxylic Acids; Dihydroergocristine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Leucine; Male; Mecamylamine; Muscarinic Antagonists; N-Methylaspartate; Naloxone; Narcotic Antagonists; Nicotinic Antagonists; Pain Measurement; Quinazolines; Rats; Rats, Sprague-Dawley; Serine; Spinal Cord; Thapsigargin; Triazoles | 2003 |
[Case report on a patient with SUNCT-syndrome].
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Functional Laterality; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Middle Aged; Neuralgia; Pain; Syndrome; Treatment Outcome | 2003 |
Gabapentin and posttraumatic stress disorder.
Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Cyclohexanecarboxylic Acids; Cyclohexanols; Depressive Disorder, Major; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Stress Disorders, Post-Traumatic; Venlafaxine Hydrochloride | 2003 |
Complete vasomotor collapse: an unusual manifestation of the carotid sinus reflex.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Morphine; Narcotic Antagonists; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley | 2003 |
Gabapentin blocks and reverses antinociceptive morphine tolerance in the rat paw-pressure and tail-flick tests.
Topics: Acetates; Amines; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Tolerance; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Morphine; Narcotic Antagonists; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Tail | 2003 |
Treatment of restless legs syndrome with gabapentin: a double-blind, cross-over study.
Topics: Acetates; Amines; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dizziness; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Research Design; Restless Legs Syndrome; Sample Size | 2003 |
Comment on: Serpell et al., gabapentin in neuropathic pain syndromes: a randomised double-blind, placebo controlled trial (Pain 2002; 99: 557-66).
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pain Measurement; Randomized Controlled Trials as Topic; Research Design | 2003 |
A case of cutaneous leukocytoclastic vasculitis associated with gabapentin.
Topics: Acetates; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Foot; Gabapentin; gamma-Aminobutyric Acid; Humans; Vasculitis, Leukocytoclastic, Cutaneous | 2003 |
An East-West approach to the management of central post-stroke pain.
Topics: Acetates; Acupuncture; Aged; Amines; Amitriptyline; Analgesics, Opioid; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Pain; Pain Management; Physical Therapy Modalities; Stroke; Tramadol; Triazines | 2003 |
Gabapentin for the treatment of ethanol withdrawal.
Topics: Acetates; Adult; Alcohol Withdrawal Seizures; Amines; Anticonvulsants; Benzodiazepines; Central Nervous System Depressants; Cyclohexanecarboxylic Acids; Ethanol; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Retrospective Studies; Substance Withdrawal Syndrome; Substance-Related Disorders | 2003 |
Simultaneous isocratic HPLC determination of vigabatrin and gabapentin in human plasma by dansyl derivatization.
Topics: Acetates; Amines; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Dansyl Compounds; Gabapentin; gamma-Aminobutyric Acid; Humans; Vigabatrin | 2003 |
Magnesium chloride and ruthenium red attenuate the antiallodynic effect of intrathecal gabapentin in a rat model of postoperative pain.
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Calcium Channels; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Spinal; Magnesium Chloride; Male; Morphine; Pain Measurement; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Ruthenium Red; Spermine | 2003 |
Gabapentin: the first preemptive anti-hyperalgesic for opioid withdrawal hyperalgesia?
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Mastectomy, Radical; Morphine; Pain, Postoperative; Substance Withdrawal Syndrome | 2003 |
ATP-sensitive potassium channels in rat primary afferent neurons: the effect of neuropathic injury and gabapentin.
Topics: Acetates; Amines; Animals; ATP-Binding Cassette Transporters; Basal Ganglia; Cyclohexanecarboxylic Acids; Diazoxide; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Glyburide; KATP Channels; Male; Neurons, Afferent; Neuroprotective Agents; Pain; Peripheral Nervous System Diseases; Pinacidil; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley | 2003 |
A comparison of Ca2+ channel blocking mode between gabapentin and verapamil: implication for protection against hypoxic injury in rat cerebrocortical slices.
Topics: Acetates; Amines; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cells, Cultured; Cerebral Cortex; Cyclohexanecarboxylic Acids; Fetus; Gabapentin; gamma-Aminobutyric Acid; Hypoxia, Brain; Nitric Oxide; omega-Agatoxin IVA; omega-Conotoxin GVIA; Potassium Chloride; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Verapamil | 2003 |
Gabapentin exposure in human pregnancy: results from the Gabapentin Pregnancy Registry.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Registries; Retrospective Studies; Surveys and Questionnaires | 2003 |
Gabapentin in geriatric mania.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Valproic Acid | 2003 |
Acute effects of gabapentin and pregabalin on rat forebrain cellular GABA, glutamate, and glutamine concentrations.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Injections, Intraperitoneal; Magnetic Resonance Spectroscopy; Male; Neurons; Pregabalin; Prosencephalon; Rats; Rats, Long-Evans; Vigabatrin | 2003 |
Doctor explains why he blew the whistle.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Drug Approval; Drug Industry; Drug Labeling; Fraud; Gabapentin; gamma-Aminobutyric Acid; Government Regulation; Humans; Marketing; Physicians; United States; United States Food and Drug Administration; Whistleblowing | 2003 |
Court papers suggest scale of drug's use: lawsuit says doctors were paid endorsers.
Topics: Acetates; Amines; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Approval; Drug Industry; Drug Labeling; Gabapentin; gamma-Aminobutyric Acid; Humans; Marketing; Physicians; Professional Misconduct; United States; Whistleblowing | 2003 |
Procedure for the monitoring of gabapentin with 2,4,6-trinitrobenzene sulfonic acid derivatization followed by HPLC with ultraviolet detection.
Topics: Acetates; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Monitoring; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Reference Standards; Spectrophotometry, Ultraviolet; Trinitrobenzenesulfonic Acid | 2003 |
Gabapentin blocks L-type and P/Q-type Ca2+ channels involved in depolarization-stimulated nitric oxide synthase activity in primary cultures of neurons from mouse cerebral cortex.
Topics: Acetates; Amines; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Mice; Molecular Sequence Data; Neurons; Nifedipine; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; omega-Conotoxin GVIA; Potassium Chloride; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2003 |
Incomplete Brown-Séquard syndrome after methamphetamine injection into the neck.
Topics: Acetates; Adult; Amines; Brown-Sequard Syndrome; Causalgia; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Infarction; Injections; Lorazepam; Male; Methamphetamine; Morphine; Neck; Sclerosing Solutions; Spinal Cord; Spinal Cord Injuries; Spinal Cord Ischemia; Substance Abuse, Intravenous; Vasoconstrictor Agents | 2003 |
Vigabatrin, but not gabapentin or topiramate, produces concentration-related effects on enzymes and intermediates of the GABA shunt in rat brain and retina.
Topics: 4-Aminobutyrate Transaminase; Acetates; Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Fructose; Gabapentin; gamma-Aminobutyric Acid; Male; Rats; Rats, Sprague-Dawley; Retina; Topiramate; Vigabatrin; Visual Fields | 2003 |
Different actions of gabapentin and baclofen in hippocampus from weaver mice.
Topics: Acetates; Amines; Animals; Baclofen; Cyclohexanecarboxylic Acids; Down-Regulation; Excitatory Amino Acid Antagonists; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Neural Inhibition; Organ Culture Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyramidal Cells; Receptors, GABA-B; Species Specificity; Synaptic Transmission | 2003 |
The truth is out there.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Drug Industry; Gabapentin; gamma-Aminobutyric Acid; Legislation, Drug; United States; United States Food and Drug Administration | 2003 |
Parke-Davis whistle-blower speaks at last.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Drug Industry; Gabapentin; gamma-Aminobutyric Acid; Humans; United States; United States Food and Drug Administration | 2003 |
The trend to move palliative care upstream.
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Meningoencephalitis; Methadone; Pain; Pain Management; Palliative Care; Treatment Outcome; United States; West Nile Fever | 2003 |
Gabapentin reduces the mechanosensitivity of fine afferent nerve fibres in normal and inflamed rat knee joints.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Inflammation; Knee Joint; Male; Mechanotransduction, Cellular; Neurons, Afferent; Rats; Rats, Wistar | 2003 |
Treatment of post-herpetic pain in myasthenia gravis: exacerbation of weakness due to gabapentin.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Middle Aged; Myasthenia Gravis; Pain | 2003 |
Tiagabine synergistically interacts with gabapentin in the electroconvulsive threshold test in mice.
Topics: Acetates; Amines; Animals; Avoidance Learning; Behavior, Animal; Brain Chemistry; Cyclohexanecarboxylic Acids; Differential Threshold; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Excitatory Amino Acid Antagonists; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Memory; Mice; Motor Activity; Nipecotic Acids; Pain Threshold; Psychomotor Performance; Reaction Time; Tiagabine | 2003 |
Three drug reviews: one reformulated and one new antifungal agent and optimal dosing of the anticonvulsant gabapentin.
Topics: Acetates; Amines; Amphotericin B; Anticonvulsants; Antifungal Agents; Chemistry, Pharmaceutical; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Pyrimidines; Triazoles; Voriconazole | 2003 |
Inflammation unmasks gabapentin's effect on A delta-fiber evoked excitatory postsynaptic currents in substantia gelatinosa neurons of rat spinal cord.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Nerve Fibers, Myelinated; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Channels; Substantia Gelatinosa; Synaptic Transmission; Tetrodotoxin | 2003 |
Helicobacter pylori hiccup.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Helicobacter Infections; Helicobacter pylori; Hiccup; Humans | 2003 |
Gabapentin reverses mechanical allodynia induced by sciatic nerve ischemia and formalin-induced nociception in mice.
Topics: Acetates; Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Disease Models, Animal; Erythrosine; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hyperalgesia; Lasers; Light; Male; Mice; Mice, Inbred Strains; Motor Activity; Pain Measurement; Photochemistry; Sciatic Nerve; Sciatic Neuropathy | 2003 |
[Effect of anticonvulsant gabapentin on visceral nociception and its relationship with amino acid neurotransmitters released from spinal cord].
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Male; Neurotransmitter Agents; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord; Viscera | 2003 |
Hemodynamic effects of gabapentin in rats.
Topics: Acetates; Amines; Analgesics; Animals; Blood Pressure; Catheterization; Cyclohexanecarboxylic Acids; Diastole; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Male; Rats; Rats, Sprague-Dawley; Systole; Time Factors | 2003 |
Gabapentin actions on Kir3 currents and N-type Ca2+ channels via GABAB receptors in hippocampal pyramidal cells.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Baclofen; Barium; Calcium Channel Blockers; Calcium Channels, N-Type; Cell Membrane; Cesium; Cyclohexanecarboxylic Acids; Epilepsy; Ethylmaleimide; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Gabapentin; gamma-Aminobutyric Acid; GTP-Binding Proteins; Hippocampus; Male; omega-Conotoxin GVIA; Organ Culture Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 2003 |
Treatment of chronic neuropathic pain after traumatic central cervical cord lesion with gabapentin.
Topics: Acetates; Amines; Amitriptyline; Analgesics; Arm; Carbamazepine; Central Cord Syndrome; Cervical Vertebrae; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Magnetic Resonance Imaging; Male; Middle Aged; Muscle Weakness; Pain, Intractable; Spinal Cord; Treatment Outcome | 2003 |
Reinforcing versus anticonvulsant drugs: effects on intracranial self-stimulation rate-frequency M50 indices.
Topics: Acetates; Amines; Amphetamine; Animals; Anticonvulsants; Central Nervous System Stimulants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Male; Medial Forebrain Bundle; Pentobarbital; Rats; Rats, Long-Evans; Reinforcement, Psychology; Self Stimulation | 2003 |
Potent analgesic effects of anticonvulsants on peripheral thermal nociception in rats.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Calcium Channel Blockers; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Female; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hyperalgesia; Neurons, Afferent; Pain Measurement; Peripheral Nervous System Diseases; Phenytoin; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers | 2003 |
Acute effects of gabapentin on laboratory measures of aggressive and escape responses of adult parolees with and without a history of conduct disorder.
Topics: Acetates; Adult; Aggression; Amines; Conduct Disorder; Cyclohexanecarboxylic Acids; Escape Reaction; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Prisoners; Research Design | 2004 |
Studies on the GABA pathway. I. The inhibition of gamma-aminobutyric acid-alpha-ketoglutaric acid transaminase in vitro and in vivo by U-7524 (amino-oxyacetic acid).
Topics: Acetates; Amino Acids; gamma-Aminobutyric Acid; In Vitro Techniques; Ketoglutaric Acids; Transaminases | 1961 |
PROTECTIVE EFFECT OF GAMMA-AMINOBUTYRIC ACID ON EXPERIMENTAL AMMONIA INTOXICATION.
Topics: Acetates; Aminobutyrates; Ammonia; Ammonium Chloride; Ammonium Compounds; Arginine; Brain; gamma-Aminobutyric Acid; Glucose; Glutamates; Histidine; Hydrochloric Acid; Neurochemistry; Pharmacology; Phosphates; Quaternary Ammonium Compounds; Rats; Research; Toxicology | 1964 |
[TRANSAMINATION OF KETO ACIDS WITH GAMMA-AMINOBUTYRIC ACID AND ITS RELATION TO GLYOXYLIC ACID].
Topics: Acetates; Amination; Aminobutyrates; gamma-Aminobutyric Acid; Glyoxylates; Keto Acids; Research | 1965 |
Clinical and electroencephalographic correlates of GABA-transaminase inhibition in man.
Topics: 4-Aminobutyrate Transaminase; Acetates; Amino Acids; Electroencephalography; gamma-Aminobutyric Acid; Transaminases | 1961 |
Pregabalin and gabapentin reduce release of substance P and CGRP from rat spinal tissues only after inflammation or activation of protein kinase C.
Topics: Acetates; Amines; Analgesics; Animals; Calcitonin Gene-Related Peptide; Cyclohexanecarboxylic Acids; Enzyme Activation; Foot; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Inflammation; Male; Phorbol 12,13-Dibutyrate; Pregabalin; Protein Kinase C; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P | 2003 |
Comparative activity of the anti-convulsants oxcarbazepine, carbamazepine, lamotrigine and gabapentin in a model of neuropathic pain in the rat and guinea-pig.
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Guinea Pigs; Hyperalgesia; Lamotrigine; Male; Neuralgia; Oxcarbazepine; Pain Threshold; Pressure; Rats; Rats, Wistar; Sciatic Nerve; Touch; Triazines; Wounds and Injuries | 2003 |
Great auricular neuralgia: a case report.
Topics: Acetates; Aged; Amines; Analgesics; Cervical Vertebrae; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuralgia; Spinal Osteophytosis | 2003 |
Chronic pain syndrome after laparoscopic radical nephrectomy.
Topics: Acetates; Aged; Amines; Analgesics; Analgesics, Opioid; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Fentanyl; Flank Pain; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Neoplasms; Laparoscopy; Male; Middle Aged; Neoplasm Staging; Nephrectomy; Pain, Postoperative; Syndrome | 2003 |
Alpha-gamma hybrid peptides that contain the conformationally constrained gabapentin residue: characterization of mimetics of chain reversals.
Topics: Acetates; Amines; Biomimetic Materials; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; Dipeptides; Gabapentin; gamma-Aminobutyric Acid; Hydrogen Bonding; Models, Molecular; Molecular Structure; Protein Structure, Secondary; Stereoisomerism | 2003 |
Anti-allodynic and anti-oedematogenic properties of the extract and lignans from Phyllanthus amarus in models of persistent inflammatory and neuropathic pain.
Topics: Acetates; Amines; Analgesics; Animals; Anti-Inflammatory Agents; Cyclohexanecarboxylic Acids; Edema; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; Hexanes; Inflammation; Ligation; Lignans; Male; Mice; Motor Activity; Neutrophil Infiltration; Pain; Peripheral Nervous System Diseases; Peroxidase; Phyllanthus; Physical Stimulation; Plant Extracts; Psychomotor Performance; Sciatica; Solvents | 2003 |
[Unclear chronic aches. Often depression plays a part therein].
Topics: Acetates; Amines; Analgesics, Opioid; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Tricyclic; Back Pain; Chronic Disease; Cyclohexanecarboxylic Acids; Depression; Diagnosis, Differential; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypochondriasis; Mianserin; Mirtazapine; Pain; Somatoform Disorders | 2003 |
Hiccup in patients with advanced cancer successfully treated with gabapentin: report of three cases.
Topics: Acetates; Adult; Amines; Anticonvulsants; Brain Neoplasms; Carcinoma, Small Cell; Colonic Neoplasms; Cyclohexanecarboxylic Acids; Fatal Outcome; Gabapentin; gamma-Aminobutyric Acid; Hiccup; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Pancreatic Neoplasms | 2003 |
[Gabapentin in the treatment of neuropathic pain in patients with type 2 diabetes mellitus].
Topics: Acetates; Aged; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Surveys and Questionnaires | 2003 |
The pattern of gabapentin use in a tertiary palliative care unit.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neoplasms; Pain; Palliative Care; Retrospective Studies | 2003 |
[Clinical and neurochemical aspects of diaphragmatic myoclonus].
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Diaphragm; Female; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Myoclonus; Nipecotic Acids; Tiagabine | 2003 |
Postoperative pain and analgesic responses are similar in male and female Sprague-Dawley rats.
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Cholinesterase Inhibitors; Clonidine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Foot; Gabapentin; gamma-Aminobutyric Acid; Male; Morphine; Neostigmine; Pain Measurement; Pain Threshold; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Sex Factors | 2003 |
Limited efficacy of gabapentin in severe therapy-resistant epilepsies of learning-disabled patients.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Learning Disabilities; Long-Term Care; Residential Facilities; Retrospective Studies | 2003 |
Treatment of neuropathic orbital pain with gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Eye Diseases; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain | 2003 |
Gabapentin-induced hypoglycemia in a long-term peritoneal dialysis patient.
Topics: Acetates; Amines; C-Peptide; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Gluconeogenesis; Humans; Hypoglycemia; Hypotension; Insulin; Kidney Cortex; Kidney Failure, Chronic; Liver; Middle Aged; Pancreas; Parathyroidectomy; Peritoneal Dialysis; Postoperative Complications | 2003 |
[Efficacy and tolerability of gabapentin in the treatment of patients with neuropathic pain. Results of an observational study involving 5620 patients].
Topics: Acetates; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia; Pain Measurement; Patient Satisfaction; Time Factors | 2003 |
Genotype-dependence of gabapentin and pregabalin sensitivity: the pharmacogenetic mediation of analgesia is specific to the type of pain being inhibited.
Topics: Acetates; Amines; Analgesia; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Genotype; Male; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; Pain; Pain Measurement; Pharmacogenetics; Pregabalin; Species Specificity | 2003 |
entla, a novel epileptic and ataxic Cacna2d2 mutant of the mouse.
Topics: Acetates; Alleles; Amines; Animals; Ataxia; Base Sequence; Blotting, Southern; Blotting, Western; Calcium; Calcium Channels; Cell Membrane; Chromosome Mapping; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Electrophysiology; Epilepsy; Exons; Female; Gabapentin; gamma-Aminobutyric Acid; Genetic Vectors; Genotype; Hippocampus; Homozygote; Immunohistochemistry; Ligands; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Models, Genetic; Molecular Sequence Data; Mutation; Phenotype; Protein Binding; Protein Structure, Tertiary; Time Factors | 2004 |
The use of clinical trial simulation to support dose selection: application to development of a new treatment for chronic neuropathic pain.
Topics: Acetates; Amines; Analgesics; Chronic Disease; Clinical Trials, Phase II as Topic; Computer Simulation; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Models, Chemical; Models, Statistical; Pain; Pain Measurement | 2003 |
A nitric oxide (NO)-releasing derivative of gabapentin, NCX 8001, alleviates neuropathic pain-like behavior after spinal cord and peripheral nerve injury.
Topics: Acetates; Amines; Animals; Aorta, Thoracic; Behavior, Animal; Cyclic GMP; Cyclohexanecarboxylic Acids; Cyclohexanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intraperitoneal; Lipopolysaccharides; Macrophages; Male; Mice; Muscle, Smooth; Nitrates; Nitric Oxide; Pain; Pain Measurement; PC12 Cells; Peripheral Nerve Injuries; Peripheral Nerves; Rabbits; Randomized Controlled Trials as Topic; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Spinal Cord Injuries; Tumor Necrosis Factor-alpha; Vasodilation | 2004 |
Determination of gabapentin in human plasma by capillary electrophoresis with laser-induced fluorescence detection and acetonitrile stacking technique.
Topics: Acetates; Acetonitriles; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Electrophoresis, Capillary; Gabapentin; gamma-Aminobutyric Acid; Humans; Lasers; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 2004 |
Migraine-tic syndrome: a case report of a new headache type.
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Gabapentin; gamma-Aminobutyric Acid; Headache Disorders; Humans; Migraine Disorders; Treatment Outcome; Trigeminal Neuralgia | 2004 |
Asterixis and toxic encephalopathy induced by gabapentin.
Topics: Acetates; Aged; Amines; Anticonvulsants; Brain; Brain Diseases; Carbamazepine; Cyclohexanecarboxylic Acids; Dyskinesia, Drug-Induced; Electromyography; Essential Tremor; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Motor Cortex; Oxcarbazepine | 2004 |
Change in opioid use after the initiation of gabapentin therapy in patients with postherpetic neuralgia.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; Middle Aged; Neuralgia; Retrospective Studies | 2003 |
Myoclonic jerks associated with gabapentin.
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Myoclonus; Pain | 2003 |
Synergistic interaction between spinal gabapentin and oral B vitamins in a neuropathic pain model.
Topics: Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Female; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Ligation; Pain; Pain Measurement; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Wistar; Spinal Nerves; Vitamin B Complex | 2003 |
Effect of K+ channel modulators on the antiallodynic effect of gabapentin.
Topics: Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Pain Measurement; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar | 2004 |
Reduction by gabapentin of K+-evoked release of [3H]-glutamate from the caudal trigeminal nucleus of the streptozotocin-treated rat.
Topics: Acetates; Amines; Animals; Blood Glucose; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Male; Pain; Pain Measurement; Physical Stimulation; Potassium; Rats; Trigeminal Nuclei | 2004 |
GABAA-benzodiazepine-chloride receptor-targeted therapy for tinnitus control: preliminary report.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Benzodiazepines; Chloride Channels; Clonazepam; Cyclohexanecarboxylic Acids; Female; GABA Agents; Gabapentin; gamma-Aminobutyric Acid; Humans; Instillation, Drug; Magnetic Resonance Imaging; Male; Middle Aged; Receptors, GABA; Receptors, GABA-A; Surveys and Questionnaires; Tinnitus; Tomography, Emission-Computed, Single-Photon | 2002 |
[Gabapentine-induced acute hepatitis].
Topics: Acetates; Acute Disease; Amines; Anticonvulsants; Chemical and Drug Induced Liver Injury; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 2003 |
Potentially inappropriate antiepileptic drugs for elderly patients with epilepsy.
Topics: Acetates; Aged; Amines; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Phenytoin; Retrospective Studies; Triazines | 2004 |
Endogenous GABA does not mediate the inhibitory effects of gabapentin on spinal reflexes in rats.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Neural Inhibition; Rats; Rats, Wistar; Reflex, Monosynaptic; Semicarbazides; Spinal Cord | 2004 |
Treatment with the antiepileptic drugs phenytoin and gabapentin ameliorates seizure and paralysis of Drosophila bang-sensitive mutants.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drosophila; Drosophila Proteins; Gabapentin; gamma-Aminobutyric Acid; Mutation; Paralysis; Phenytoin; Seizures | 2004 |
Gabapentin may inhibit synaptic transmission in the mouse spinal cord dorsal horn through a preferential block of P/Q-type Ca2+ channels.
Topics: Acetates; Amines; Animals; Calcium Channels, N-Type; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred BALB C; Neural Inhibition; Posterior Horn Cells; Spinal Cord; Synaptic Transmission | 2004 |
Chronic idiopathic singultus: is there life after cisapride?
Topics: Acetates; Amines; Anticonvulsants; Cisapride; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Agents; Hiccup; Humans; Indoles; Phosphodiesterase Inhibitors; Serotonin Receptor Agonists | 2004 |
Interaction between anticonvulsants and human placental carnitine transporter.
Topics: Acetates; Amines; Aminoisobutyric Acids; Anticonvulsants; Carnitine; Carrier Proteins; Culture Techniques; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Models, Biological; Nipecotic Acids; Organic Cation Transport Proteins; Phenytoin; Placenta; Pregnancy; Pregnancy Complications; Pregnancy Proteins; Solute Carrier Family 22 Member 5; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 2004 |
Sample preparation and determination of gabapentin in venous and capillary blood using liquid chromatography-tandem mass spectrometry.
Topics: Acetates; Amines; Capillaries; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Mass Spectrometry; Pilot Projects; Veins | 2004 |
Autonomous stump movements responsive to gabapentin.
Topics: Acetates; Aged; Amines; Amputation Stumps; Cyclohexanecarboxylic Acids; Dyskinesias; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 2004 |
A study of gabapentin in the treatment of tonic-clonic seizures of alcohol withdrawal syndrome.
Topics: Acetates; Alcohol Withdrawal Seizures; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 2004 |
Painful neuropathy alters the effect of gabapentin on sensory neuron excitability in rats.
Topics: Acetates; Action Potentials; Amines; Analgesics; Analysis of Variance; Animals; Calcium Channels; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electrophysiology; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Male; Microelectrodes; Nerve Fibers, Myelinated; Neurons, Afferent; Pain; Rats; Sciatic Nerve | 2004 |
Hot flashes refractory to HRT and SSRI therapy but responsive to gabapentin therapy.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hormone Replacement Therapy; Hot Flashes; Humans; Selective Serotonin Reuptake Inhibitors; Treatment Failure | 2004 |
Effects of the suppression of acute herpetic pain by gabapentin and amitriptyline on the incidence of delayed postherpetic pain in mice.
Topics: Acetates; Amines; Amitriptyline; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Simplex; Herpesvirus 1, Human; Mice; Mice, Inbred BALB C; Pain; Physical Stimulation; Time Factors | 2004 |
N-Acridin-9-yl-butane-1,4-diamine derivatives: high-affinity ligands of the alpha2delta subunit of voltage gated calcium channels.
Topics: Acetates; Amines; Binding, Competitive; Calcium Channels; Cyclohexanecarboxylic Acids; Diamines; Gabapentin; gamma-Aminobutyric Acid; Ligands; Molecular Structure; Protein Binding; Protein Subunits; Structure-Activity Relationship | 2004 |
Vulvodynia.
Topics: Acetates; Amines; Anticonvulsants; Antidepressive Agents, Tricyclic; Biofeedback, Psychology; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Pain Management; Paresthesia; Vulvar Diseases | 2004 |
Can gabapentin be a safe alternative to hormonal therapy in the treatment of inappropriate sexual behavior in demented patients?
Topics: Acetates; Aged; Alzheimer Disease; Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hormones; Humans; Male; Sexual Behavior; Sexual Dysfunctions, Psychological | 2003 |
Gabapentin (Neurontin) for chronic pain.
Topics: Acetates; Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Costs; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain | 2004 |
Brachioradial pruritus: response to treatment with gabapentin.
Topics: Acetates; Aged; Amines; Arm; Cyclohexanecarboxylic Acids; Dermatologic Agents; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pruritus; Treatment Outcome | 2004 |
The use of gabapentin in a 12-year-old boy with cancer pain.
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Child; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Morphine; Pain; Sarcoma, Ewing; Spinal Neoplasms; Treatment Outcome | 2004 |
Characteristic of interactions between intrathecal gabapentin and either clonidine or neostigmine in the formalin test.
Topics: Acetates; Adrenergic alpha-Agonists; Amines; Analgesics; Animals; Cholinesterase Inhibitors; Clonidine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Neostigmine; Pain Measurement; Rats; Rats, Sprague-Dawley | 2004 |
Determination of gabapentin-lactam in serum of patients under gabapentin therapy.
Topics: Acetates; Adult; Amines; Anticonvulsants; Aza Compounds; Chromatography, Ion Exchange; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Spiro Compounds | 2004 |
Input resistance is voltage dependent due to activation of Ih channels in rat CA1 pyramidal cells.
Topics: 4-Aminopyridine; Acetates; Amines; Animals; Animals, Newborn; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Radiation; Electric Impedance; Electric Stimulation; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Ion Channel Gating; Ion Channels; Membrane Potentials; Nickel; Patch-Clamp Techniques; Potassium Channel Blockers; Pyramidal Cells; Pyrimidines; Rats; Rats, Wistar; Tetrodotoxin | 2004 |
Use of gabapentin in the prevention of taxane-induced arthralgias and myalgias.
Topics: Acetates; Amines; Analgesics; Antineoplastic Agents, Phytogenic; Arthralgia; Cyclohexanecarboxylic Acids; Docetaxel; Gabapentin; gamma-Aminobutyric Acid; Humans; Muscle, Skeletal; Muscular Diseases; Paclitaxel; Retrospective Studies; Taxoids | 2004 |
Anticonvulsants as anxiolytics, part 2: Pregabalin and gabapentin as alpha(2)delta ligands at voltage-gated calcium channels.
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Anxiety Disorders; Calcium Channels; Cyclohexanecarboxylic Acids; Fear; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Ligands; Pregabalin; Synaptic Transmission | 2004 |
Out with the old and in with the new...epilepsy drugs.
Topics: Acetates; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Drug Therapy; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Health Planning Guidelines; Humans | 2004 |
Pfizer pleads guilty, but drug sales continue to soar.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Drug Industry; Drug Labeling; Gabapentin; gamma-Aminobutyric Acid; Humans; Marketing; United States | 2004 |
Anticonvulsants and the relief of chronic pain: pregabalin and gabapentin as alpha(2)delta ligands at voltage-gated calcium channels.
Topics: Acetates; Amines; Anticonvulsants; Calcium Channels; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ligands; Pain; Pain Measurement; Pregabalin; Somatoform Disorders; Synaptic Transmission | 2004 |
Dose-dependent severe arthralgia induced by gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Arthralgia; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Reflex Sympathetic Dystrophy | 2004 |
Conquering peripheral neuropathic pain.
Topics: Acetates; Amines; Analgesics; Anesthetics, Local; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Neuralgia | 2004 |
Superior oblique myokymia improved with gabapentin.
Topics: Acetates; Administration, Oral; Aged; Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Trochlear Nerve Diseases | 2004 |
Effectiveness of gabapentin for treatment of burning mouth syndrome.
Topics: Acetates; Aged; Amines; Burning Mouth Syndrome; Cyclohexanecarboxylic Acids; Female; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans | 2004 |
Warner-Lambert found guilty of promoting neurontin off label.
Topics: Acetates; Advertising; Amines; Cyclohexanecarboxylic Acids; Drug Industry; Gabapentin; gamma-Aminobutyric Acid; Humans; Product Labeling | 2004 |
Profiles in patient safety: when an error occurs.
Topics: Acetates; Aged; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Administration Schedule; Emergency Medicine; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypotension; Hypoxia; Medication Errors; Pain; Phenytoin; Treatment Outcome | 2004 |
Gabapentin and behavioral disorders in severe Alzheimer disease.
Topics: Acetates; Aged; Aged, 80 and over; Alzheimer Disease; Amines; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 2004 |
Future Pain Drugs - Europe 2003. 15-16 September 2003, London, UK.
Topics: Acetaminophen; Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Delivery Systems; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Levetiracetam; Nitrates; Pain; Peripheral Nervous System Diseases; Piracetam; Pregabalin; Topiramate | 2003 |
Differential analgesic sensitivity of two distinct neuropathic pain models.
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Animals; Cold Temperature; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dizocilpine Maleate; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Male; Morphine; Nerve Crush; Neuroprotective Agents; Pain; Pain Measurement; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy | 2004 |
Pharmacological characterisation of the rat brachial plexus avulsion model of neuropathic pain.
Topics: Acetates; Amines; Analgesics; Analysis of Variance; Animals; Brachial Plexus; Brachial Plexus Neuropathies; Celecoxib; Clonidine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Ketamine; Lidocaine; Male; Morphine; Neuralgia; Nociceptors; Pain Measurement; Pain Threshold; Pyrazoles; Radiculopathy; Rats; Rats, Wistar; Sulfonamides | 2004 |
Phantom breast pain as a source of functional loss.
Topics: Acetates; Activities of Daily Living; Amines; Anti-Anxiety Agents; Breast Neoplasms; Carcinoma in Situ; Comorbidity; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mastectomy, Modified Radical; Middle Aged; Multiple Sclerosis; Pain Measurement; Perceptual Disorders | 2004 |
Whole-brain glutamate metabolism evaluated by steady-state kinetics using a double-isotope procedure: effects of gabapentin.
Topics: Acetates; Amines; Animals; Astrocytes; Bicarbonates; Brain; Brain Chemistry; Carbon Isotopes; Chromatography; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Magnetic Resonance Spectroscopy; Male; Models, Neurological; Neurons; Rats; Rats, Sprague-Dawley; Regression Analysis; Retina; Time Factors | 2004 |
The biology and pharmacology of calcium channel alpha2-delta proteins Pfizer Satellite Symposium to the 2003 Society for Neuroscience Meeting. Sheraton New Orleans Hotel, New Orleans, LA November 10, 2003.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Binding Sites; Calcium Channels; Calcium Channels, L-Type; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Humans; Mice; Pregabalin; Rats; Societies, Scientific | 2004 |
Mechanism of action of alpha2delta ligands: voltage sensitive calcium channel (VSCC) modulators.
Topics: Acetates; Amines; Analgesics; Anti-Anxiety Agents; Anticonvulsants; Calcium Channel Blockers; Calcium Channels; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ligands; Models, Neurological; Pregabalin; Protein Structure, Quaternary; Sodium Channels; Structure-Activity Relationship | 2004 |
Intrathecal gabapentin enhances the analgesic effects of subtherapeutic dose morphine in a rat experimental pancreatitis model.
Topics: Acetates; Acute Disease; Amines; Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Bradykinin; Catheterization; Cholestasis; Cyclohexanecarboxylic Acids; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Morphine; Pain; Pain Measurement; Pancreatitis; Rats; Rats, Sprague-Dawley | 2004 |
[Anticonvulsant hypersensitivity syndrome].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug Hypersensitivity; Ethosuximide; Fever; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lymphatic Diseases; Phenobarbital; Phenytoin; Syndrome; Triazines; Valproic Acid | 2004 |
The effects of intrathecal gabapentin on spinal morphine tolerance in the rat tail-flick and paw pressure tests.
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Tolerance; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Morphine; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reaction Time | 2004 |
Essential tremor in the older adult: coping with primary symptoms.
Topics: Acetates; Adaptation, Psychological; Adrenergic beta-Antagonists; Aged; Alprazolam; Amines; Anticonvulsants; Antiparkinson Agents; Botulinum Toxins, Type A; Cyclohexanecarboxylic Acids; Essential Tremor; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuromuscular Agents; Primidone; Propranolol; Severity of Illness Index | 2004 |
Comparison of the antinociceptive profiles of gabapentin and 3-methylgabapentin in rat models of acute and persistent pain: implications for mechanism of action.
Topics: Acetates; Acute Disease; Amines; Analgesics; Animals; Benzylamines; Chronic Disease; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Pain; Phosphinic Acids; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 2005 |
The novel GABA adamantane derivative (AdGABA): design, synthesis, and activity relationship with gabapentin.
Topics: Acetates; Adamantane; Amines; Analgesics; Animals; Anticonvulsants; Calcium Channels; Cell Line; Cell Membrane; Cyclohexanecarboxylic Acids; Drug Design; Gabapentin; gamma-Aminobutyric Acid; Humans; Mice; Models, Animal; Molecular Structure; Pentylenetetrazole; Rats; Semicarbazides; Structure-Activity Relationship | 2005 |
The contribution of GABA to glutamate/glutamine cycling and energy metabolism in the rat cortex in vivo.
Topics: Acetates; Amino Acids; Anesthetics, Inhalation; Animals; Biological Transport; Blood Glucose; Cerebral Cortex; Energy Metabolism; GABA Modulators; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Halothane; Magnetic Resonance Spectroscopy; Male; Neuroglia; Neurons; Oxidation-Reduction; Pentobarbital; Rats; Rats, Sprague-Dawley | 2005 |
Response of brain amino acid metabolism to ketosis.
Topics: Acetates; Acetyl Coenzyme A; Amino Acids; Animals; Aspartate Aminotransferases; Aspartic Acid; Brain; Brain Chemistry; Carbon Radioisotopes; Energy Metabolism; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Ketosis; Male; Mice; Models, Animal; Oxaloacetic Acid | 2005 |
Novel parent structures for inhibitors of the murine GABA transporters mGAT3 and mGAT4.
Topics: Acetates; Animals; beta-Alanine; Cell Line; Chlorocebus aethiops; COS Cells; Dose-Response Relationship, Drug; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Guanidines; Humans; Membrane Transport Modulators; Membrane Transport Proteins; Mice; Molecular Structure; Neurotransmitter Uptake Inhibitors; Plasmids; Propionates; Serine; Structure-Activity Relationship; Thiazoles; Transfection; Tritium | 2005 |
Role of periaqueductal grey prostaglandin receptors in formalin-induced hyperalgesia.
Topics: Acetates; Acrylamides; Animals; Benzyl Compounds; Dimethyl Sulfoxide; Extracellular Fluid; Formaldehyde; gamma-Aminobutyric Acid; Glutamic Acid; Hyperalgesia; Injections, Intraventricular; Male; Mice; Microdialysis; Misoprostol; Naphthalenes; Pain Measurement; Periaqueductal Gray; Prostaglandin Antagonists; Receptors, Prostaglandin E; Thiophenes; Triazoles; Xanthones | 2006 |
Increased brain monocarboxylic acid transport and utilization in type 1 diabetes.
Topics: Acetates; Adult; Biological Transport; Brain; Diabetes Mellitus, Type 1; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Insulin; Kinetics; Male; Reference Values | 2006 |
Quantification of cortical GABA-glutamine cycling rate using in vivo magnetic resonance signal of [2-13C]GABA derived from glia-specific substrate [2-13C]acetate.
Topics: Acetates; Animals; Cerebral Cortex; Cyclohexanecarboxylic Acids; Enzyme Inhibitors; Female; gamma-Aminobutyric Acid; Glucose; Glutamine; Kinetics; Macaca mulatta; Magnetic Resonance Spectroscopy; Male; Neuroglia; Rats; Rats, Sprague-Dawley; Vigabatrin | 2007 |
Different metabolism of glutamatergic and GABAergic compartments in superfused hippocampal slices characterized by nuclear magnetic resonance spectroscopy.
Topics: 4-Aminopyridine; Acetates; Action Potentials; Animals; Astrocytes; Carbon Radioisotopes; Energy Metabolism; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Hippocampus; Magnetic Resonance Spectroscopy; Male; Neurons; Organ Culture Techniques; Potassium Channel Blockers; Rats; Rats, Wistar; Time Factors; Tricarboxylic Acids; Up-Regulation | 2007 |
Glutamatergic and GABAergic neurotransmitter cycling and energy metabolism in rat cerebral cortex during postnatal development.
Topics: Acetates; Algorithms; Amino Acids; Animals; Blood Glucose; Brain Chemistry; Cerebral Cortex; Citric Acid Cycle; Data Interpretation, Statistical; Energy Metabolism; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Kinetics; Magnetic Resonance Spectroscopy; Male; Neuroglia; Neurons; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley | 2007 |
Central nervous system depressant activity of an ethyl acetate extract from Ipomoea stans roots.
Topics: Acetates; Animals; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Central Nervous System Depressants; Cerebral Cortex; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Ipomoea; Male; Mice; Mice, Inbred ICR; Motor Activity; Neurotransmitter Agents; Pentobarbital; Pentylenetetrazole; Plant Extracts; Plant Roots; Seizures; Solvents; Swimming | 2007 |
Influence of thyroid hormone and thyroid hormone receptors in the generation of cerebellar gamma-aminobutyric acid-ergic interneurons from precursor cells.
Topics: Acetates; Age Factors; Animals; Blotting, Western; Cell Differentiation; Cell Proliferation; Cerebellum; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Hypothyroidism; Immunohistochemistry; Interneurons; Ki-67 Antigen; Mice; Mice, Inbred BALB C; PAX2 Transcription Factor; Phenols; Rats; Rats, Wistar; Receptors, Thyroid Hormone; Thyroid Hormones | 2007 |
Altered cerebral glucose and acetate metabolism in succinic semialdehyde dehydrogenase-deficient mice: evidence for glial dysfunction and reduced glutamate/glutamine cycling.
Topics: Acetates; Amino Acids; Animals; Animals, Newborn; Blood Glucose; Carbon Isotopes; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Mice; Mice, Knockout; Neuroglia; Sodium Oxybate; Succinate-Semialdehyde Dehydrogenase; Time Factors | 2007 |
Quantitation with QUEST of brain HRMAS-NMR signals: application to metabolic disorders in experimental epileptic seizures.
Topics: Acetates; Alanine; Algorithms; Animals; Aspartic Acid; Brain; Choline; gamma-Aminobutyric Acid; Glutamine; Inositol; Lactates; Magnetic Resonance Spectroscopy; Mice; Monte Carlo Method; Soman; Status Epilepticus | 2008 |
Demonstration of neuron-glia transfer of precursors for GABA biosynthesis in a co-culture system of dissociated mouse cerebral cortex.
Topics: Acetates; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Coculture Techniques; gamma-Aminobutyric Acid; Glucose; Lactates; Mass Spectrometry; Mice; Neuroglia; Neurons; Spectrometry, Fluorescence | 2008 |
Mechanisms underlying Li+ effects in glutamatergic and GABAergic neurotransmissions in the adult rat brain and in primary cultures of neural cells as revealed by 13C NMR.
Topics: Acetates; Animals; Astrocytes; Brain; Carbon Isotopes; Cell Survival; Cells, Cultured; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Lithium Chloride; Magnetic Resonance Spectroscopy; Male; Neurons; Rats; Rats, Wistar; Synaptic Transmission | 2009 |
Chloride accumulation drives volume dynamics underlying cell proliferation and migration.
Topics: Acetates; Analysis of Variance; Bumetanide; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Size; Chlorides; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Glioblastoma; Green Fluorescent Proteins; Humans; Imaging, Three-Dimensional; Indenes; Membrane Potentials; Patch-Clamp Techniques; Picrotoxin; Sodium Potassium Chloride Symporter Inhibitors; Transfection | 2009 |
Elevated endogenous GABA concentration attenuates glutamate-glutamine cycling between neurons and astroglia.
Topics: 4-Aminobutyrate Transaminase; Acetates; Analysis of Variance; Animals; Astrocytes; Brain; Carbon Isotopes; Carbon Radioisotopes; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Injections, Intravenous; Magnetic Resonance Spectroscopy; Male; Neurons; Rats; Rats, Sprague-Dawley; Vigabatrin | 2009 |
Synthesis and biological evaluation of 4-fluoroproline and 4-fluoropyrrolidine-2-acetic acid derivatives as new GABA uptake inhibitors.
Topics: Acetates; Animals; Cell Line; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; Inhibitory Concentration 50; Mice; Proline; Pyrrolidines; Structure-Activity Relationship | 2009 |
The alpha(2)delta subunit augments functional expression and modifies the pharmacology of Ca(V)1.3 L-type channels.
Topics: Acetates; Amines; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Line; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Patch-Clamp Techniques; Rabbits; Rats; Recombinant Fusion Proteins | 2009 |
Knockout of GAD65 has major impact on synaptic GABA synthesized from astrocyte-derived glutamine.
Topics: Acetates; Animals; Astrocytes; Blotting, Western; Cerebral Cortex; Citric Acid Cycle; GABA Agents; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Glucose; Glutamate Decarboxylase; Glutamic Acid; Glutamine; Hippocampus; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Mice, Knockout; Synapses; Vigabatrin | 2011 |
Synthesis of neurotransmitter GABA via the neuronal tricarboxylic acid cycle is elevated in rats with liver cirrhosis consistent with a high GABAergic tone in chronic hepatic encephalopathy.
Topics: Acetates; Ammonia; Animals; Astrocytes; Brain Chemistry; Chromatography, High Pressure Liquid; Chronic Disease; Citric Acid Cycle; Coculture Techniques; Common Bile Duct; Excitatory Amino Acids; Female; gamma-Aminobutyric Acid; Hepatic Encephalopathy; Ligation; Liver Cirrhosis; Mass Spectrometry; Mice; Neurons; Neurotransmitter Agents; Rats; Rats, Wistar | 2011 |
Rat brain slices oxidize glucose at high rates: a (13)C NMR study.
Topics: Acetates; Anesthesia; Anesthetics; Animals; Aspartic Acid; Brain; Carbon Isotopes; gamma-Aminobutyric Acid; Glucose; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Glutamine; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvic Acid; Rats; Rats, Wistar | 2011 |
Glutamatergic and GABAergic metabolism in mouse brain under chronic nicotine exposure: implications for addiction.
Topics: Acetates; Animals; Behavior, Animal; Brain; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Nicotine; Oxidation-Reduction; Signal Transduction; Substance-Related Disorders | 2012 |
Glutamate metabolism is impaired in transgenic mice with tau hyperphosphorylation.
Topics: Acetates; Animals; Astrocytes; Cerebellar Cortex; Dementia; Female; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Hippocampus; Humans; Male; Mice; Mice, Transgenic; Mutation; Neurons; Neurotransmitter Agents; Phosphorylation; tau Proteins; Transgenes | 2013 |
Microbial succession and metabolite changes during long-term storage of Kimchi.
Topics: Acetates; Candida; Fermentation; Food Handling; Food Microbiology; Food Storage; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Lactic Acid; Lactobacillus; Leuconostoc; Magnetic Resonance Spectroscopy; Mannitol; Polymorphism, Restriction Fragment Length; Principal Component Analysis; RNA, Ribosomal, 16S; Saccharomyces; Sequence Analysis, DNA; Succinic Acid; Weissella | 2013 |
Glutamatergic and GABAergic TCA cycle and neurotransmitter cycling fluxes in different regions of mouse brain.
Topics: Acetates; Animals; Astrocytes; Brain; Carbon Isotopes; Citric Acid Cycle; Energy Metabolism; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Models, Biological; Neurons; Neurotransmitter Agents | 2013 |
Differential effects of ethanol on regional glutamatergic and GABAergic neurotransmitter pathways in mouse brain.
Topics: Acetates; Algorithms; Amino Acids; Animals; Astrocytes; Brain Chemistry; Central Nervous System Depressants; Cerebellum; Cerebral Cortex; Ethanol; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Kinetics; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Neurons; Neurotransmitter Agents; Signal Transduction; Synaptic Transmission | 2014 |
Cochrane, and the truth about gabapentin for migraine.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; gamma-Aminobutyric Acid; Humans; Male; Migraine Disorders | 2014 |
Exercise modulates chloride homeostasis after spinal cord injury.
Topics: Acetates; Animals; Brain-Derived Neurotrophic Factor; Bumetanide; Chloride Channels; Chlorides; Cordotomy; Exercise Therapy; Female; gamma-Aminobutyric Acid; Gene Expression Regulation; H-Reflex; Homeostasis; Indenes; K Cl- Cotransporters; Nerve Tissue Proteins; Random Allocation; Rats; Rats, Sprague-Dawley; Solute Carrier Family 12, Member 2; Spinal Cord Injuries; Symporters; Tibial Nerve | 2014 |
Involvement of medullary GABAergic system in extraterritorial neuropathic pain mechanisms associated with inferior alveolar nerve transection.
Topics: Acetates; Action Potentials; Animals; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Hyperalgesia; Indenes; Mandibular Nerve; Medulla Oblongata; Muscimol; Neurons; Pain Threshold; Physical Stimulation; Rats; Rats, Transgenic; Time; Trigeminal Nerve Injuries; Vesicular Inhibitory Amino Acid Transport Proteins | 2015 |
Acute spinal cord injury (SCI) transforms how GABA affects nociceptive sensitization.
Topics: Acetates; Analysis of Variance; Animals; Bicuculline; Bumetanide; Capsaicin; Disease Models, Animal; GABA Agents; gamma-Aminobutyric Acid; Gene Expression Regulation; Hyperalgesia; Indenes; K Cl- Cotransporters; Lipopolysaccharides; Male; MAP Kinase Signaling System; Muscimol; Nociception; Pain Measurement; Physical Stimulation; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium Potassium Chloride Symporter Inhibitors; Spinal Cord Injuries; Symporters; Time Factors | 2016 |
Glucose, Lactate, β-Hydroxybutyrate, Acetate, GABA, and Succinate as Substrates for Synthesis of Glutamate and GABA in the Glutamine-Glutamate/GABA Cycle.
Topics: 3-Hydroxybutyric Acid; Acetates; Animals; Astrocytes; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Humans; Lactic Acid; Neurons; Succinates | 2016 |
Effect of a new cyclic derivative of GABA, RGPU-207, on the functions of cardiac and cerebral mitochondria of stressed animals.
Topics: Acetates; Animals; Antioxidants; Catalase; Cerebral Cortex; Electron Transport; gamma-Aminobutyric Acid; Glutathione Peroxidase; Heart; Lipid Peroxidation; Male; Malondialdehyde; Mitochondria; Myocardium; Oxidation-Reduction; Oxidative Stress; Oxygen Consumption; Phenylhydrazines; Piracetam; Pyrrolidinones; Rats; Rats, Wistar; Stress, Psychological; Superoxide Dismutase | 2019 |
Postharvest treatments with γ-aminobutyric acid, methyl jasmonate, or methyl salicylate enhance chilling tolerance of blood orange fruit at prolonged cold storage.
Topics: Acetates; Ascorbate Peroxidases; Catalase; Citrus sinensis; Cold Temperature; Cyclopentanes; Food Preservation; Food Preservatives; Food Storage; Fruit; gamma-Aminobutyric Acid; Oxylipins; Plant Proteins; Salicylates | 2019 |
Blood oranges maintain bioactive compounds and nutritional quality by postharvest treatments with γ-aminobutyric acid, methyl jasmonate or methyl salicylate during cold storage.
Topics: Acetates; Anthocyanins; Catechol Oxidase; Citrus sinensis; Cold Temperature; Cyclopentanes; Food Preservation; Fruit; gamma-Aminobutyric Acid; Glucosides; Nutritive Value; Oxylipins; Phenylalanine Ammonia-Lyase; Salicylates | 2020 |
Slc38a1 Conveys Astroglia-Derived Glutamine into GABAergic Interneurons for Neurotransmitter GABA Synthesis.
Topics: Acetates; Amino Acid Transport System A; Animals; Astrocytes; gamma-Aminobutyric Acid; Glutamine; Interneurons; Mice; Models, Biological; Neurotransmitter Agents; Synapses | 2020 |
Useful Caged Compounds for Cell Physiology.
Topics: Acetates; Action Potentials; Animals; Calcium; Chelating Agents; Egtazic Acid; Ethylenediamines; gamma-Aminobutyric Acid; Glutamic Acid; Mice; Microscopy, Fluorescence, Multiphoton; Neurons; Neurotransmitter Agents | 2020 |
Enhancement of γ-aminobutyric acid (GABA) production by Lactobacillus brevis CRL 2013 based on carbohydrate fermentation.
Topics: Acetates; Amaranthus; Bread; Carbohydrate Metabolism; Carbohydrates; Chenopodium quinoa; Culture Media; Ethanol; Fermentation; gamma-Aminobutyric Acid; Lactic Acid; Levilactobacillus brevis | 2020 |
Exogenous methyl jasmonate enhances phytochemicals and delays senescence in harvested strawberries by modulating GABA shunt pathway.
Topics: Acetates; Anthocyanins; Antioxidants; Cyclopentanes; Fragaria; Fruit; gamma-Aminobutyric Acid; Oxylipins; Phytochemicals | 2022 |
Organic acids metabolism and GABA shunt involved in maintaining quality of Malus domestica by methyl jasmonate treatment.
Topics: Acetates; Aconitate Hydratase; Cyclopentanes; Fruit; gamma-Aminobutyric Acid; Malus; NADP; Oxylipins | 2022 |
In vitro Effects of Cellulose Acetate on Fermentation Profiles, the Microbiome, and Gamma-aminobutyric Acid Production in Human Stool Cultures.
Topics: Acetates; Cellulose; Feces; Fermentation; gamma-Aminobutyric Acid; Humans; Microbiota | 2023 |