phenyl acetate and avasimibe

Topics: Acetamides; Acetates; Animals; Anticholesteremic Agents; Caproates; Cell Line; Cells, Cultured; Humans; Hypolipidemic Agents; Lipoprotein(a); Sulfonamides; Sulfonic Acids

Topics: Acetamides; Acetates; Anticholesteremic Agents; Azetidines; Carrier Proteins; Cholestyramine Resin; Ezetimibe; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxysteroid Dehydrogenases; Hypercholesterolemia; Membrane Glycoproteins; Pyrimidines; Rosuvastatin Calcium; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids

Topics: Acetamides; Acetates; Azetidines; Cardiovascular Diseases; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Niacin; Pyrimidines; Rosuvastatin Calcium; Sulfonamides; Sulfonic Acids

Topics: Acetamides; Acetates; Animals; Clinical Trials as Topic; Drug Industry; Humans; Hyperlipidemias; Sulfonamides; Sulfonic Acids

Topics: Acetamides; Acetates; Animals; Arteriosclerosis; Clinical Trials as Topic; Drug Industry; Enzyme Inhibitors; Humans; Hyperlipidemias; Sulfonamides; Sulfonic Acids

Topics: Acetamides; Acetates; Animals; Anticholesteremic Agents; Clinical Trials as Topic; Enzyme Inhibitors; Humans; Hyperlipidemias; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids

Topics: Acetamides; Acetates; Adiponectin; Animals; Arteriosclerosis; Cholesterol Esters; Disease Models, Animal; Drug Design; Foam Cells; Humans; Intercellular Signaling Peptides and Proteins; Sterol O-Acyltransferase; Sterol O-Acyltransferase 2; Sulfonamides; Sulfonic Acids

Topics: Acetamides; Acetates; Animals; Cholesterol; Double-Blind Method; Enzyme Inhibitors; Humans; Randomized Controlled Trials as Topic; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids; Treatment Failure

Topics: Acetamides; Acetates; Acetyl-CoA C-Acetyltransferase; Anti-Inflammatory Agents; Anticholesteremic Agents; Antioxidants; Apolipoprotein A-I; Atherosclerosis; Cholesterol; Cholesterol Ester Transfer Proteins; Dyslipidemias; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lipoproteins, HDL; Niacin; PPAR alpha; Quinolines; Renal Insufficiency, Chronic; Sulfonamides; Sulfonic Acids; Uremia

Topics: Acetamides; Acetates; Adult; Aged; Double-Blind Method; Female; Humans; Hyperlipidemia, Familial Combined; Hypolipidemic Agents; Lipids; Lipoproteins; Male; Middle Aged; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids; Treatment Outcome

Topics: Acetamides; Acetates; Adult; Coronary Angiography; Coronary Artery Disease; Disease Progression; Double-Blind Method; Female; Humans; Hypolipidemic Agents; Male; Research Design; Statistics as Topic; Sulfonamides; Sulfonic Acids; Ultrasonography

Topics: Acetamides; Acetates; Administration, Oral; Adolescent; Adult; Age Factors; Atorvastatin; Child; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Multivariate Analysis; Probability; Pyrroles; Reference Values; Risk Assessment; Severity of Illness Index; Sex Factors; Sterol O-Acyltransferase; Sterol O-Acyltransferase 2; Sulfonamides; Sulfonic Acids; Treatment Outcome

Topics: Acetamides; Acetates; Aged; Apolipoproteins B; Biomarkers; C-Reactive Protein; Cholesterol, LDL; Coronary Artery Disease; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Image Processing, Computer-Assisted; Male; Middle Aged; Sterol O-Acyltransferase; Sterol O-Acyltransferase 2; Sulfonamides; Sulfonic Acids; Treatment Failure; Ultrasonography, Interventional

Topics: Acetamides; Acetates; Adult; Aged; Aged, 80 and over; Double-Blind Method; Enzyme Inhibitors; Exercise; Female; Follow-Up Studies; Humans; Intermittent Claudication; Lower Extremity; Male; Middle Aged; Peripheral Vascular Diseases; Psychomotor Performance; Sterol O-Acyltransferase; Sterol O-Acyltransferase 2; Sulfonamides; Sulfonic Acids; Time Factors; Treatment Outcome; United States

Topics: Acetamides; Acetates; Adenosine; Adolescent; Adult; Aged; Anticholesteremic Agents; Body Mass Index; C-Reactive Protein; Cholesterol; Cohort Studies; Coronary Artery Disease; Coronary Circulation; Data Interpretation, Statistical; Double-Blind Method; Female; Fractional Flow Reserve, Myocardial; Humans; Male; Metabolic Syndrome; Middle Aged; Plasminogen Activator Inhibitor 1; Positron-Emission Tomography; Risk Factors; Sulfonamides; Sulfonic Acids; Vascular Resistance; Vasodilator Agents; Young Adult

Topics: Acetamides; Acetates; Animals; Anticholesteremic Agents; Diet; Enzyme Inhibitors; Rabbits; Rats; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids

Topics: Acetamides; Acetates; Animal Feed; Animals; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoprotein B-100; Apolipoproteins; Apolipoproteins B; Apoprotein(a); Cells, Cultured; Cholesterol; Enzyme Inhibitors; Lipoprotein(a); Liver; Macaca fascicularis; Male; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids

Topics: Acetamides; Acetates; Animals; Aorta; Arteriosclerosis; Cholesterol; Cholesterol Esters; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Cricetinae; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Enzyme Inhibitors; Liver; Male; Reference Values; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids; Time Factors; Triglycerides

Topics: Acetamides; Acetates; Administration, Oral; Animals; Anticholesteremic Agents; Chromatography, High Pressure Liquid; Female; Male; Mass Spectrometry; Rats; Reproducibility of Results; Sulfonamides; Sulfonic Acids

Topics: Acetamides; Acetates; Apolipoprotein B-100; Apolipoproteins B; Carbon Radioisotopes; Coenzyme A; Enzyme Inhibitors; Hepatoblastoma; Humans; Hydroxymethylglutaryl CoA Reductases; Intracellular Fluid; Lipid Metabolism; Lipids; Receptors, LDL; RNA, Messenger; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids; Tumor Cells, Cultured

Topics: Acetamides; Acetates; Animals; Anticholesteremic Agents; Apolipoproteins B; Enzyme Inhibitors; Female; Lipoproteins, LDL; Lipoproteins, VLDL; Liver; Male; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids; Swine; Swine, Miniature

Topics: Acetamides; Acetates; Animals; Anticholesteremic Agents; Bile Acids and Salts; Cells, Cultured; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Cholesterol Esters; Enzyme Induction; Enzyme Inhibitors; Liver; Male; Rats; Rats, Wistar; RNA, Messenger; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids; Triglycerides

Topics: Acetamides; Acetates; Animals; Anticholesteremic Agents; Apolipoproteins B; Cricetinae; Drugs, Investigational; Enzyme Inhibitors; Humans; Liver; Male; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids

Topics: Acetamides; Acetates; Animals; Anticholesteremic Agents; Aorta, Thoracic; Arteriosclerosis; Base Sequence; Cholesterol; DNA Primers; Enzyme Inhibitors; Gene Expression; Humans; Hypercholesterolemia; Macrophages; Male; Matrix Metalloproteinases; Rabbits; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids; Tissue Inhibitor of Metalloproteinases

Topics: Acetamides; Acetates; Administration, Oral; Adrenal Glands; Alanine Transaminase; Animals; Area Under Curve; Arteriosclerosis; Cholesterol; Cytochrome P-450 Enzyme System; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Erythrocytes; Female; Hypolipidemic Agents; Liver; Longevity; Male; Microsomes, Liver; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids; Toxicity Tests

Topics: Acetamides; Acetates; Animals; Anticholesteremic Agents; Aortic Valve; Apolipoprotein E3; Apolipoproteins E; Arteriosclerosis; Body Weight; Cell Adhesion; Cell Line; Cholesterol; Diet, Atherogenic; Disease Models, Animal; Eating; Endothelium, Vascular; Female; Heterozygote; Lipoproteins; Macrophages; Mice; Mice, Transgenic; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids

Topics: Acetamides; Acetates; Animals; Arteriosclerosis; Coenzyme A-Transferases; Drug Therapy, Combination; Hydroxymethylglutaryl CoA Reductases; Hypolipidemic Agents; Rabbits; Simvastatin; Sulfonamides; Sulfonic Acids

Topics: Acetamides; Acetates; Animals; Cholesterol; Cholesterol Esters; Cricetinae; Diet, Atherogenic; DNA-Binding Proteins; Endoplasmic Reticulum, Smooth; Enzyme Inhibitors; Hydroxymethylglutaryl CoA Reductases; Intracellular Membranes; Liver; Mesocricetus; Receptors, LDL; RNA, Messenger; Simvastatin; Sterol O-Acyltransferase; Sterol Regulatory Element Binding Protein 2; Sulfonamides; Sulfonic Acids; Transcription Factors; Triglycerides

Topics: Acetamides; Acetates; Apolipoprotein B-100; Apolipoproteins B; Biological Transport; Cysteine Proteinase Inhibitors; Endoplasmic Reticulum; Enzyme Inhibitors; Golgi Apparatus; Humans; Leupeptins; Lipid Metabolism; Oleic Acid; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids; Tumor Cells, Cultured

Topics: Acetamides; Acetates; Apolipoproteins E; Cells, Cultured; Cholesterol; Humans; Lipoproteins, LDL; Macrophages; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids

Topics: Acetamides; Acetates; Atorvastatin; Cells, Cultured; Cholesterol Esters; Drug Synergism; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Macrophages; Pyrroles; Sulfonamides; Sulfonic Acids

Topics: Acetamides; Acetates; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Digoxin; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Gene Expression; Hepatocytes; Humans; Microsomes, Liver; Midazolam; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger; Sulfonamides; Sulfonic Acids

Topics: Acetamides; Acetates; Anilides; Cardiovascular Agents; Cell Line; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fenofibrate; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lipoproteins, LDL; Macrophages; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mevalonic Acid; Monocytes; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids; Tetradecanoylphorbol Acetate; Thiazolidinediones; Tissue Inhibitor of Metalloproteinase-1; Transcription Factors

Topics: Acetamides; Acetates; Anticoagulants; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C9; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hepatocytes; Humans; Kinetics; Oligonucleotide Array Sequence Analysis; Oxidoreductases, N-Demethylating; Pharmaceutical Preparations; Pregnane X Receptor; Prothrombin Time; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids; Warfarin

Topics: Acetamides; Acetates; Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Intestine, Small; Kinetics; Lipids; Lipoproteins; Liver; Metabolic Clearance Rate; Models, Biological; Postprandial Period; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids; Swine; Swine, Miniature; Triglycerides

Topics: Acetamides; Acetates; Cholesterol, LDL; Coronary Artery Disease; Coronary Vessels; Disease Progression; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Image Processing, Computer-Assisted; Male; Middle Aged; Regression Analysis; Sulfonamides; Sulfonic Acids; Total Lung Capacity; Ultrasonography, Interventional

Topics: Acetamides; Acetates; Aged; Atherosclerosis; Biomarkers; Cineangiography; Coronary Angiography; Coronary Artery Disease; Disease Progression; Drug Therapy, Combination; Dyslipidemias; Endothelium, Vascular; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Image Processing, Computer-Assisted; Male; Middle Aged; Multicenter Studies as Topic; Myocardial Infarction; Randomized Controlled Trials as Topic; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids; Ultrasonography, Interventional

Topics: Acetamides; Acetates; Animals; Aorta, Abdominal; Aortic Diseases; Atherosclerosis; Atorvastatin; Catheterization; Cholesterol; Disease Progression; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Magnetic Resonance Imaging; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Pyrroles; Rabbits; Random Allocation; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids

Topics: Acetamides; Acetates; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; CHO Cells; Cricetinae; Cricetulus; Humans; Mice; Mice, Transgenic; Protein Transport; Pyridines; Secretory Pathway; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids

Topics: Acetamides; Acetates; Acetyl-CoA C-Acetyltransferase; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cholesterol Esters; Enzyme Inhibitors; Glioma; Humans; Sulfonamides; Sulfonic Acids

Topics: Acetamides; Acetates; Aging; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Apolipoproteins E; Brain; Cholesterol; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gliosis; Humans; Image Processing, Computer-Assisted; Liver; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Peptide Fragments; Presenilin-1; Pyridines; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids

Topics: Acetamides; Acetates; Animals; Antineoplastic Agents; Apoptosis; Biological Availability; Capsules; Cell Survival; Chemistry, Pharmaceutical; Cholesterol; Esterification; Humans; Male; Mice; Safety; Serum Albumin; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids; Water

Topics: Acetamides; Acetates; Acetyl-CoA C-Acetyltransferase; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Autophagy; Benzimidazoles; Brain; Cells, Cultured; Cholesterol; Cholesterol Esters; Disease Models, Animal; Enzyme Inhibitors; Gene Knockdown Techniques; Mice, Inbred C57BL; Mice, Transgenic; Molecular Targeted Therapy; Neurons; Peptide Fragments; Presenilin-1; Sulfonamides; Sulfonic Acids; tau Proteins

Topics: Acetamides; Acetates; Acetyl-CoA C-Acetyltransferase; Animals; Atherosclerosis; CD8-Positive T-Lymphocytes; Cell Membrane; Cholesterol; Esterification; Female; Immunological Synapses; Immunotherapy; Male; Melanoma; Mice; Programmed Cell Death 1 Receptor; Receptors, Antigen, T-Cell; Signal Transduction; Sulfonamides; Sulfonic Acids

Topics: Acetamides; Acetates; Animals; Apoptosis; Cell Proliferation; Cholesterol; Down-Regulation; Drug Resistance, Neoplasm; Drug Synergism; Esterification; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; MAP Kinase Signaling System; Mice; Mutation; Protein Kinase Inhibitors; Sulfonamides; Sulfonic Acids; Xenograft Model Antitumor Assays

Topics: Acetamides; Acetates; Acetyl-CoA C-Acetyltransferase; Animals; Cancer Vaccines; Carcinoma, Squamous Cell; Cell Line, Tumor; Combined Modality Therapy; Dendritic Cells; Disease Models, Animal; Female; Head and Neck Neoplasms; Immunotherapy; Mice; Mice, Inbred C3H; Neoplasm Recurrence, Local; Squamous Cell Carcinoma of Head and Neck; Sulfonamides; Sulfonic Acids; T-Lymphocytes; Vaccines

Topics: Acetamides; Acetates; Antiviral Agents; Apolipoproteins B; Apolipoproteins E; Carrier Proteins; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Viral; Genotype; Hepacivirus; Hepatitis C, Chronic; Host-Pathogen Interactions; Humans; Lipid Metabolism; Lipid Regulating Agents; RNA, Small Interfering; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids; Virion; Virus Assembly

Topics: Acetamides; Acetates; Amino Acid Sequence; Animals; Cancer Vaccines; Cholesterol; Disease Progression; Lung Neoplasms; Mice; Proto-Oncogene Proteins p21(ras); Sulfonamides; Sulfonic Acids; T-Lymphocytes, Regulatory; Vaccines, Subunit