phentolamine has been researched along with wb 4101 in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (36.11) | 18.7374 |
| 1990's | 18 (50.00) | 18.2507 |
| 2000's | 4 (11.11) | 29.6817 |
| 2010's | 1 (2.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blaxall, HS; Bylund, DB; Caron, MG; Iversen, LJ; Lefkowitz, RJ; Lomasney, JW | 1 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Timmermans, PB; van Zwieten, PA | 1 |
| Foglar, R; Horie, K; Obika, K; Ogawa, S; Sakamoto, A; Shibata, K; Tsujimoto, G | 1 |
| Bondinell, WE; Hieble, JP; Ruffolo, RR | 1 |
| Denis-Pouxviel, C; Devedjian, JC; Esclapez, F; Paris, H | 1 |
| Gaivin, RJ; Gonzalez-Cabrera, P; Perez, DM; Ross, SA; Waugh, DJ; Yun, J; Zuscik, MJ | 1 |
| Pedretti, A; Testa, B; Villa, L; Vistoli, G | 1 |
| Kapur, H; Mottram, DR | 2 |
| Aniukhovskiĭ, EP; Rozen, MP; Staĭnberg, SF | 1 |
| Nijkamp, FP; van Buuren, KJ; Veenstra, DM | 1 |
| Han, CD; Minneman, KP | 1 |
| Hashimoto, S; Kigoshi, S; Muramatsu, I; Ohmura, T; Oshita, M | 1 |
| Terman, BI | 1 |
| Miller, JF; Proudfit, HK | 1 |
| Gross, G; Hanft, G | 1 |
| Alexander, BS; Broadhurst, AM; Wood, MD | 1 |
| Battaglia, G; Creese, I; Morrow, AL; Norman, AB | 1 |
| Creese, I; Morrow, AL | 1 |
| Dubocovich, ML; Langer, SZ; Massingham, R; Shepperson, NB | 1 |
| Humphrey, SJ; McCall, RB | 1 |
| Gerald, MC; Snider, RM | 1 |
| Campbell, IC; Feer, H; Kräuchi, K; Wirz-Justice, A | 1 |
| Proudfit, HK; Sagen, J | 1 |
| Bigg, DC; Koek, W; Sleight, AJ | 1 |
| Badia, A; Sallés, J | 1 |
| Docherty, JR; Kearns, S; O'Rourke, M | 1 |
| Aghajanian, GK; Marek, GJ | 1 |
| Hwa, J; Perez, DM; Zhao, MM | 1 |
| Chiba, T; Fukutomi, J; Hattori, K; Maruyama, K; Nagatomo, T; Takeda, M; Yamaguchi, M | 1 |
| Caramona, MM; Figueiredo, IV; Guimarães, S; Moura, D; Paiva, MQ | 1 |
| García-Sáinz, JA; Torres-Padilla, ME | 1 |
| Koss, MC; Yu, Y | 1 |
| Campos, M; Morais, Pde L; Pupo, AS | 1 |
| Côrrea, FM; Crestani, CC; Fabri, DR; Gomes, FV; Hott, SC; Reis, DG; Resstel, LB | 1 |
2 review(s) available for phentolamine and wb 4101
| Article | Year |
|---|---|
alpha 2 adrenoceptors: classification, localization, mechanisms, and targets for drugs.
Topics: Adipose Tissue; Animals; Blood Platelets; Central Nervous System; Humans; Islets of Langerhans; Melanocytes; Muscle, Smooth, Vascular; Nerve Endings; Norepinephrine; Parasympathetic Nervous System; Radioligand Assay; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Serotonin; Synapses | 1982 |
Alpha- and beta-adrenoceptors: from the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification.
Topics: Animals; Humans; Molecular Biology; Molecular Structure; Radioligand Assay; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1995 |
34 other study(ies) available for phentolamine and wb 4101
| Article | Year |
|---|---|
Pharmacological characteristics of alpha 2-adrenergic receptors: comparison of pharmacologically defined subtypes with subtypes identified by molecular cloning.
Topics: Adrenergic alpha-Antagonists; Animals; Cell Line; Cell Membrane; Cloning, Molecular; DNA; Humans; Lung; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tumor Cells, Cultured | 1992 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
KMD-3213, a novel, potent, alpha 1a-adrenoceptor-selective antagonist: characterization using recombinant human alpha 1-adrenoceptors and native tissues.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Calcium; Cell Line; CHO Cells; Clonidine; Cloning, Molecular; Cricetinae; Humans; Indoles; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Sulfonamides; Tamsulosin | 1995 |
Further characterization of human alpha 2-adrenoceptor subtypes: [3H]RX821002 binding and definition of additional selective drugs.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cell Line; Dioxanes; Humans; Idazoxan; Plasmids; Radioligand Assay; Receptors, Adrenergic, alpha; Transfection | 1994 |
Phe-308 and Phe-312 in transmembrane domain 7 are major sites of alpha 1-adrenergic receptor antagonist binding. Imidazoline agonists bind like antagonists.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Amino Acid Sequence; Animals; Cell Membrane; Clonidine; Conserved Sequence; Cricetinae; Dihydropyridines; Dioxanes; Humans; Imidazoles; Models, Molecular; Molecular Sequence Data; Oxymetazoline; Phenylalanine; Piperazines; Prazosin; Protein Structure, Secondary; Rats; Receptors, Adrenergic, alpha-1; Structure-Activity Relationship | 2001 |
Range and sensitivity as descriptors of molecular property spaces in dynamic QSAR analyses.
Topics: Chemical Phenomena; Chemistry, Physical; Ligands; Models, Molecular; Molecular Conformation; Monte Carlo Method; Quantitative Structure-Activity Relationship; Receptors, Adrenergic, alpha-1; Solvents | 2005 |
The interaction of WB4101, and other alpha-adrenoceptor antagonists, on 5-hydroxytryptamine receptors.
Topics: Adrenergic alpha-Antagonists; Animals; Biogenic Amines; Dioxanes; Dioxins; In Vitro Techniques; Male; Moxisylyte; Muscle Contraction; Muscle, Smooth; Phentolamine; Phenyl Ethers; Rats; Receptors, Serotonin; Stomach; Vas Deferens; Yohimbine | 1979 |
[Modulation of heart rhythm by alpha-1 adrenoreceptors].
Topics: Animals; Arrhythmias, Cardiac; Clonidine; Dioxanes; Dogs; Electrocardiography; Heart Rate; Myocardial Ischemia; Phentolamine; Rats; Receptors, Adrenergic, alpha | 1992 |
Determination of alpha 1-adrenoceptor subtype selectivity by [3H]-prazosin displacement studies in guinea-pig cerebral cortex and rat spleen membranes.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Cerebral Cortex; Dioxanes; Guinea Pigs; Male; Phentolamine; Prazosin; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Spleen | 1992 |
Interaction of subtype-selective antagonists with alpha 1-adrenergic receptor binding sites in rat tissues.
Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Clonidine; Dihydropyridines; Dioxanes; Kinetics; Male; Membranes; Phentolamine; Piperazines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Time Factors | 1991 |
Pharmacological subclassification of alpha 1-adrenoceptors in vascular smooth muscle.
Topics: Acetonitriles; Adrenergic alpha-Antagonists; Animals; Blood Vessels; Clonidine; Dioxanes; Dogs; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Phentolamine; Prazosin; Rabbits; Rats; Receptors, Adrenergic, alpha; Species Specificity; Yohimbine | 1990 |
[The identification and characteristics of subpopulations of alpha 1-adrenergic receptors].
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Brain Chemistry; Calcium; Clonidine; Dioxanes; GTP-Binding Proteins; Liver; Microsomes; Phentolamine; Prazosin; Rats; Receptors, Adrenergic, alpha | 1990 |
Antagonism of stimulation-produced antinociception from ventrolateral pontine sites by intrathecal administration of alpha-adrenergic antagonists and naloxone.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Dopamine beta-Hydroxylase; Electric Stimulation; Female; Injections, Spinal; Methysergide; Microinjections; Naloxone; Neurons; Pain; Phentolamine; Pons; Propranolol; Rats; Rats, Inbred Strains; Reaction Time; Yohimbine | 1990 |
Subclassification of alpha 1-adrenoceptor recognition sites by urapidil derivatives and other selective antagonists.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Dioxanes; Heart; In Vitro Techniques; Male; Myocardium; Phenethylamines; Phentolamine; Piperazines; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetralones; Yohimbine | 1989 |
Heterogeneous 3H-rauwolscine binding sites in rat cortex: two alpha 2-adrenoceptor subtypes or an additional non-adrenergic interaction?
Topics: Animals; Binding Sites; Binding, Competitive; Cerebral Cortex; Creatinine; Dioxanes; Drug Combinations; Hippocampus; Ketanserin; Male; Methysergide; Phentolamine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Spiperone; Spiro Compounds; Yohimbine | 1988 |
Identification of subtypes of [3H]prazosin-labelled alpha 1 receptor binding sites in rat brain.
Topics: Animals; Binding Sites; Brain Chemistry; Dioxanes; In Vitro Techniques; Male; Phentolamine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tritium | 1985 |
Characterization of alpha 1-adrenergic receptor subtypes in rat brain: a reevaluation of [3H]WB4104 and [3H]prazosin binding.
Topics: Animals; Binding, Competitive; Brain; Dioxanes; Dioxins; Epinephrine; Kinetics; Mathematics; Norepinephrine; Phentolamine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1986 |
In vivo selectivity of prazosin but not of WB4101 for postsynaptic alpha-1 adrenoceptors.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Cats; Dioxanes; Dioxins; Dogs; Female; Heart Rate; Male; Nictitating Membrane; Norepinephrine; Phentolamine; Prazosin; Quinazolines; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Spleen; Synapses | 1981 |
Evidence for a central depressor action of postsynaptic alpha 1-adrenergic receptor antagonists.
Topics: Adrenergic alpha-Antagonists; Animals; Cats; Clonidine; Depression, Chemical; Dioxanes; Hemodynamics; Phentolamine; Piperoxan; Prazosin; Pressoreceptors; Receptors, Adrenergic; Sympathetic Nervous System | 1981 |
Noradrenergic-mediated potentiation of acetylcholine release from the phrenic nerve: evidence for presynaptic alpha 1-adrenoceptor involvement.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Phentolamine; Phenylephrine; Phrenic Nerve; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1982 |
Adrenoceptor changes in spontaneous hypertensive rats: a circadian approach.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Brain; Brain Stem; Cerebral Cortex; Circadian Rhythm; Clonidine; Dihydroalprenolol; Dioxanes; Hypertension; Hypothalamus; Kinetics; Male; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic | 1983 |
Effect of intrathecally administered noradrenergic antagonists on nociception in the rat.
Topics: Animals; Brain Mapping; Brain Stem; Dioxanes; Efferent Pathways; Injections, Spinal; Male; Norepinephrine; Pain; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Spinal Cord; Yohimbine | 1984 |
Effects of WB4101 on blood pressure responses in the anaesthetised rat.
Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Dioxanes; Dioxins; Dose-Response Relationship, Drug; Male; Norepinephrine; Phentolamine; Phenylephrine; Rats; Sympathetic Nervous System | 1981 |
Binding of antipsychotic drugs at alpha 1A- and alpha 1B-adrenoceptors: risperidone is selective for the alpha 1B-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Binding Sites; Dioxanes; Hippocampus; In Vitro Techniques; Isoxazoles; Male; Phentolamine; Piperazines; Piperidines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Risperidone; Spleen | 1993 |
Selective enrichment with alpha 1A- and alpha 1B-adrenoceptor subtypes in rat brain cortical membranes.
Topics: Adrenergic alpha-Antagonists; Alkylating Agents; Alkylation; Animals; Binding Sites; Cerebral Cortex; Clonidine; Cystamine; Dihydropyridines; Dioxanes; Phenoxybenzamine; Phentolamine; Prazosin; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha | 1994 |
Investigation of the actions of chloroethylclonidine in rat aorta.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Aorta; Clonidine; Cystamine; Dioxanes; Dose-Response Relationship, Drug; Drug Synergism; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxathiins; Phenoxybenzamine; Phentolamine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Spiperone; Xylazine; Yohimbine | 1995 |
Alpha 1B-adrenoceptor-mediated excitation of piriform cortical interneurons.
Topics: Action Potentials; Adrenergic alpha-Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dioxanes; In Vitro Techniques; Interneurons; Male; Norepinephrine; Oxathiins; Phentolamine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Risperidone; Spiperone | 1996 |
Identification of critical extracellular loop residues involved in alpha 1-adrenergic receptor subtype-selective antagonist binding.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Amino Acid Sequence; Animals; Binding Sites; Cattle; COS Cells; Cricetinae; Dioxanes; Dogs; Humans; Molecular Sequence Data; Mutation; Phentolamine; Protein Structure, Secondary; Rats; Receptors, Adrenergic, alpha-1; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Structure-Activity Relationship | 1996 |
Two district alpha(1)-adrenoceptor subtypes in the human prostate: assessment by radioligand binding assay using 3H-prazosin.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Binding, Competitive; Dioxanes; Humans; In Vitro Techniques; Kinetics; Male; Nifedipine; Phentolamine; Piperazines; Prazosin; Prostate; Protein Binding; Radioligand Assay; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin; Tritium | 1996 |
Prejunctional alpha2A-autoreceptors in the human gastric and ileocolic arteries.
Topics: Adrenergic alpha-Antagonists; Aged; Arteries; Autoreceptors; Colon; Dioxanes; Dopamine Antagonists; Dose-Response Relationship, Drug; Electric Stimulation; Female; Gastric Mucosa; Humans; Idazoxan; Ileum; In Vitro Techniques; Male; Middle Aged; Neuromuscular Junction; Norepinephrine; Phentolamine; Prazosin; Receptors, Adrenergic, alpha-2; Spiro Compounds; Stomach; Tritium; Yohimbine | 1998 |
Modulation of basal intracellular calcium by inverse agonists and phorbol myristate acetate in rat-1 fibroblasts stably expressing alpha1d-adrenoceptors.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Cell Line; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Endothelin-1; Fibroblasts; Norepinephrine; Phentolamine; Piperazines; Protein Kinase C; Rats; Receptors, Adrenergic, alpha-1; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1999 |
Functional characterization of alpha-adrenoceptors mediating pupillary dilation in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic Fibers; Animals; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Injections, Intravenous; Male; Mydriasis; Norepinephrine; Phenoxybenzamine; Phentolamine; Piperazines; Prazosin; Pupil; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Yohimbine | 2003 |
Effects of castration and of testosterone replacement on alpha(1)-adrenoceptor subtypes in the rat vas deferens.
Topics: Animals; Castration; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Male; Muscle Contraction; Neuronal Plasticity; Norepinephrine; Phentolamine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Testosterone; Time Factors; Vas Deferens; Yohimbine | 2003 |
Both α1- and β1-adrenoceptors in the bed nucleus of the stria terminalis are involved in the expression of conditioned contextual fear.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Conditioning, Psychological; Dioxanes; Electroshock; Fear; Idazoxan; Imidazoles; Male; Phentolamine; Propanolamines; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta-1; Septal Nuclei | 2012 |