Page last updated: 2024-08-17

phentolamine and cyclosporine

phentolamine has been researched along with cyclosporine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (27.27)18.2507
2000's2 (18.18)29.6817
2010's6 (54.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Carrier, M; Pelletier, LC; Stewart, D; Tronc, F1
Carrier, M; Pelletier, LC; Tronc, F1
Carrier, M; Pelletier, LC; Thai, P1
Berggren, PO; Bokvist, K; Buschard, K; Gromada, J; Hansen, J; Høy, M; Juhl, K; Xiao-Gang, W1
Bennett, T; Fallgren, B; Gardiner, SM; Kemp, PA; March, JE1

Reviews

1 review(s) available for phentolamine and cyclosporine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

10 other study(ies) available for phentolamine and cyclosporine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Dose-dependent effect of cyclosporin on renal arterial resistance in dogs.
    The American journal of physiology, 1991, Volume: 261, Issue:6 Pt 2

    Topics: Animals; Blood; Cyclosporine; Diltiazem; Dogs; Dose-Response Relationship, Drug; Endothelins; Kidney; Nitric Oxide; Nitroglycerin; Phentolamine; Receptors, Adrenergic, alpha; Renal Artery; Renal Veins; Sympathectomy; Vascular Resistance

1991
[Effect of therapeutic doses of cyclosporine injected into the renal and femoral arteries in dogs].
    Annales de chirurgie, 1991, Volume: 45, Issue:9

    Topics: Animals; Cyclosporine; Dogs; Dose-Response Relationship, Drug; Femoral Artery; Lumbosacral Region; Phentolamine; Receptors, Adrenergic, alpha; Renal Artery; Sympathectomy; Vascular Resistance; Vasoconstriction

1991
Vasoconstrictor effect of cyclosporin on the mesenteric artery in the dog.
    Transplant international : official journal of the European Society for Organ Transplantation, 1994, Volume: 7, Issue:6

    Topics: Animals; Blood Flow Velocity; Cyclosporine; Dogs; Dose-Response Relationship, Drug; Infusions, Intra-Arterial; Mesenteric Arteries; Nitroglycerin; Perfusion; Phentolamine; Receptors, Adrenergic, alpha; Vasoconstriction

1994
Phentolamine inhibits exocytosis of glucagon by Gi2 protein-dependent activation of calcineurin in rat pancreatic alpha -cells.
    The Journal of biological chemistry, 2001, Jan-12, Volume: 276, Issue:2

    Topics: Adenylate Cyclase Toxin; Animals; Calcineurin; Cells, Cultured; Clorgyline; Cyclosporine; Cystamine; Diazoxide; Exocytosis; Glucagon; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; Imidazoles; Indoles; Islets of Langerhans; Male; Membrane Potentials; Nitriles; Oligodeoxyribonucleotides, Antisense; Pertussis Toxin; Phentolamine; Potassium Channels; Proto-Oncogene Proteins; Pyrethrins; Rats; Rats, Inbred Lew; Virulence Factors, Bordetella

2001
Regional haemodynamic effects of cyclosporine A, tacrolimus and sirolimus in conscious rats.
    British journal of pharmacology, 2004, Volume: 141, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cyclosporine; Drug Interactions; Heart Rate; Hemodynamics; Immunosuppressive Agents; Indans; Infusions, Intravenous; Losartan; Male; Phentolamine; Propranolol; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Renal Circulation; Sirolimus; Tacrolimus

2004