Page last updated: 2024-08-17

phentolamine and cimetidine

phentolamine has been researched along with cimetidine in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199028 (68.29)18.7374
1990's5 (12.20)18.2507
2000's2 (4.88)29.6817
2010's6 (14.63)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Bugajski, J; Zacny, E1
Andersson, RG; Colldahl, H; Lindgren, BR1
McCulloch, MW; Medgett, IC; Rand, MJ1
Quirion, R; Regoli, D; Rioux, F; St-Pierre, S1
Duane, SF; Niewoehner, DE; Stewart, RM; Weir, EK1
Wikberg, J1
Bhandare, PN; D'Souza, RS; Dhume, VG1
Dikshit, M; Srimal, RC1
Bennardini, F; Campana, S; Failli, P; Franconi, F; Giotti, A; Matucci, R; Stendardi, I1
Chiba, S; Haruta, K; Homma, N; Horiuchi, A; Iwatsuki, K; Yonekura, H1
Grunstein, MM; Tanaka, DT1
Hasegawa, J; Hirai, S; Hisatome, I; Kotake, H; Mashiba, H1
Glick, SD; Hough, LB; Su, K1
Salim, AS1
Chiba, S; Furuta, S; Horiuchi, A; Iwatsuki, K; Oguchi, H1
Betti, R; Casanueva, FF; Cella, SG; Müller, EE1
Chiba, S; Horiuchi, A; Iwatsuki, K; Yamagishi, F1
Abman, SH; Accurso, FJ; Ward, RM; Wilkening, RB1
Bradley, EL; Fowler, KC; Gelman, S; Tverskoy, M1
Citak, MS; Crass, MF; Moore, PL; Pang, PK; Strickland, ML1
Goadsby, PJ; Lambert, GA; Lance, JW1
Gazelius, B; Olgart, L; Panopoulos, P1
Bugajski, J; Zacny, E; Zdebska, A1
Baskin, EP; Winquist, RJ1
Toda, N1
Mészáros, J; Szegi, J1
Fiegler, M; Gerber, E; Jávor, T; Mózsik, G; Nagy, L; Past, T; Ruzsa, C; Vezekényi, Z1
Rand, MJ; Story, DF; Wong-Dusting, HK1
Ecknauer, R; Johnson, LR; Rosenfeld, GC; Thompson, WJ1
Betti, R; Casanueva, F; Chieli, T; Cocchi, D; Mantegazza, P; Müller, EE1
Homma, I; Iwase, M; Kanamaru, M1
Acuña, Y; Campos, HA; Israel, A; Mathison, Y1
Gao, C; Hu, Hz; Liu, S; Ren, J; Wood, JD; Xia, Y1
Chen, DP; Diao, YP; Lin, Y; Yao, QY; Ye, DM1

Reviews

1 review(s) available for phentolamine and cimetidine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

40 other study(ies) available for phentolamine and cimetidine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Effect of histamine H2-receptor antagonist, cimetidine, on hypothermia induced by an alpha-adrenergic agonist, clonidine, in the rat [proceedings].
    Agents and actions, 1979, Volume: 9, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Body Temperature; Cimetidine; Clonidine; Drug Interactions; Guanidines; Phentolamine; Rats

1979
Inhibitory effects of imidazolines on histamine liberation from human leukocytes and on tracheal smooth muscle tone.
    Acta pharmacologica et toxicologica, 1978, Volume: 42, Issue:5

    Topics: Animals; Cattle; Cimetidine; Clemastine; Clonidine; Guinea Pigs; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine Release; Humans; Imidazoles; Leukocytes; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Phentolamine; Phenylephrine; Propranolol; Tolazoline

1978
Effects of the histamine H2-receptor blocking drugs burimamide and cimetidine on noradrenergic transmission in the isolated aorta of the rabbit and atria of the guinea-pig.
    British journal of pharmacology, 1979, Volume: 67, Issue:4

    Topics: Animals; Aorta, Thoracic; Burimamide; Cimetidine; Cocaine; Female; Guanidines; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Rabbits; Synaptic Transmission; Thiourea

1979
An analysis of the negative inotropic action of somatostatin.
    British journal of pharmacology, 1979, Volume: 66, Issue:2

    Topics: Acetylcholine; Animals; Atropine; Calcium; Cimetidine; Diphenhydramine; Guinea Pigs; Indomethacin; Methysergide; Myocardial Contraction; Phentolamine; Practolol; Rabbits; Rats; Somatostatin

1979
Distal airway responses to changes in oxygen and carbon dioxide tensions.
    Respiration physiology, 1979, Volume: 38, Issue:3

    Topics: Animals; Carbon Dioxide; Cimetidine; Dogs; In Vitro Techniques; Indomethacin; Lung; Meclofenamic Acid; Muscle Tonus; Muscle, Smooth; Oxygen; Phentolamine; Propranolol; Prostaglandins; Prostaglandins E; Prostaglandins F

1979
Differentiation between pre- and postjunctional alpha-receptors in guinea pig ileum and rabbit aorta.
    Acta physiologica Scandinavica, 1978, Volume: 103, Issue:3

    Topics: Animals; Aorta, Thoracic; Cimetidine; Clonidine; Dibenzylchlorethamine; Dose-Response Relationship, Drug; Electric Stimulation; Epinephrine; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Oxymetazoline; Parasympathetic Nervous System; Phenoxybenzamine; Phentolamine; Phenylephrine; Rabbits; Receptors, Adrenergic; Tolazoline

1978
Aggravating action of clonidine on ethanol-induced gastric lesions: probable mechanism of action.
    Indian journal of physiology and pharmacology, 1990, Volume: 34, Issue:4

    Topics: Animals; Cimetidine; Clonidine; Drug Synergism; Ethanol; Male; Naloxone; Phentolamine; Rats; Rats, Inbred Strains; Receptors, Histamine H2; Receptors, Opioid; Stomach Ulcer

1990
Evidence for the presence of a new plasma factor which acts synergistically to ADP induced platelet aggregation.
    Life sciences, 1990, Volume: 47, Issue:2

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenosine Diphosphate; Animals; Biological Factors; Cimetidine; Drug Synergism; Enzymes; Epoprostenol; Heparin; Indomethacin; Ketanserin; Macaca mulatta; Male; Masoprocol; Mice; Mice, Inbred Strains; Phentolamine; Platelet Aggregation

1990
Effect of taurine, L-cysteic and orthanilic acids on cardiac tension.
    Progress in clinical and biological research, 1990, Volume: 351

    Topics: Animals; beta-Alanine; Calcium Chloride; Cimetidine; Cysteic Acid; Drug Interactions; Gallopamil; Guinea Pigs; In Vitro Techniques; Indomethacin; Isoproterenol; Male; Myocardial Contraction; Phentolamine; Phenylephrine; Propranolol; Sulfanilic Acids; Taurine

1990
Effects of DN-9693, a synthesized phosphodiesterase inhibitor, on pancreatic exocrine secretion in dogs.
    Japanese journal of pharmacology, 1989, Volume: 49, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Atropine; Cholecystokinin; Cimetidine; Dogs; Dose-Response Relationship, Drug; Female; Male; Pancreas; Pancreatic Juice; Papaverine; Phentolamine; Phosphodiesterase Inhibitors; Propranolol; Quinazolines; Secretin; Sulpiride; Theophylline

1989
Vasoactive effects of substance P on isolated rabbit pulmonary artery.
    Journal of applied physiology (Bethesda, Md. : 1985), 1985, Volume: 58, Issue:4

    Topics: Animals; Atropine; Biomechanical Phenomena; Chlorpheniramine; Cimetidine; Dose-Response Relationship, Drug; Epinephrine; In Vitro Techniques; Isometric Contraction; Meclofenamic Acid; Muscle Relaxation; Neostigmine; Phentolamine; Pulmonary Artery; Rabbits; Serotonin; Substance P; Tetrodotoxin

1985
Inotropic effect of thyrotropin-releasing hormone on the guinea pig myocardium.
    Endocrinology, 1988, Volume: 123, Issue:6

    Topics: Action Potentials; Animals; Calcium; Calcium Channels; Cimetidine; Diltiazem; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Kinetics; Manganese; Metoclopramide; Myocardial Contraction; Norepinephrine; Phentolamine; Potassium; Stimulation, Chemical; Thyrotropin-Releasing Hormone; Verapamil

1988
A role for histamine and histamine H2-receptors in non-opiate footshock-induced analgesia.
    Life sciences, 1985, Mar-04, Volume: 36, Issue:9

    Topics: Animals; Cimetidine; Electroshock; Haloperidol; Histamine; Histamine H2 Antagonists; Male; Naloxone; Pain; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H2

1985
Inhibition of basal and insulin-stimulated gastric acid secretion by phenoxybenzamine or phentolamine.
    The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:7

    Topics: Animals; Atropine; Cimetidine; Female; Gastric Acid; Insulin; Male; Phenoxybenzamine; Phentolamine; Rats; Receptors, Adrenergic; Serotonin; Vagus Nerve

1987
Effects of human atrial natriuretic polypeptide on pancreatic exocrine secretion in the dog.
    Biochemical and biophysical research communications, 1987, Jul-31, Volume: 146, Issue:2

    Topics: Animals; Atrial Natriuretic Factor; Atropine; Bicarbonates; Cimetidine; Dogs; Ethacrynic Acid; Female; Haloperidol; Injections, Intra-Arterial; Male; Pancreatic Juice; Pancreatin; Perfusion; Phentolamine; Propranolol; Proteins; Secretin; Sodium; Sulpiride

1987
Activation of the cholinergic system and growth hormone release in the dog: functional interactions with other neurotransmitters.
    Acta endocrinologica, 1985, Volume: 108, Issue:1

    Topics: Animals; Behavior, Animal; Cimetidine; Clemastine; Diphenhydramine; Dogs; Domperidone; Female; Fenfluramine; Growth Hormone; Male; Metergoline; Naloxone; Phentolamine; Physostigmine; Pimozide; Pizotyline; Propranolol; Radioimmunoassay; Receptors, Cholinergic; Synaptic Transmission

1985
Effects of forskolin on pancreatic exocrine secretion and cyclic nucleotide concentrations of the dog pancreas.
    Archives internationales de pharmacodynamie et de therapie, 1987, Volume: 286, Issue:2

    Topics: Animals; Atropine; Cimetidine; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Female; Male; Nucleotides, Cyclic; Pancreatic Juice; Phentolamine; Propranolol; Sulpiride; Verapamil

1987
Adaptation of fetal pulmonary blood flow to local infusion of tolazoline.
    Pediatric research, 1986, Volume: 20, Issue:11

    Topics: Animals; Blood Pressure; Cimetidine; Diphenhydramine; Female; Fetus; Heart Rate; Phentolamine; Pregnancy; Pulmonary Circulation; Sheep; Tolazoline; Verapamil

1986
Influence of fentanyl and morphine on intestinal circulation.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:6

    Topics: Animals; Blood Gas Analysis; Cesium Radioisotopes; Cimetidine; Dogs; Drug Interactions; Fentanyl; Hydrogen-Ion Concentration; Injections, Intravenous; Intestine, Small; Microspheres; Morphine; Oxygen Consumption; Pentobarbital; Phentolamine; Promethazine; Radioisotopes; Regional Blood Flow; Rubidium; Vascular Resistance; Vasoconstriction

1985
Cardiovascular responses to parathyroid hormone.
    The American journal of physiology, 1985, Volume: 249, Issue:2 Pt 1

    Topics: Animals; Atropine; Blood Pressure; Cimetidine; Coronary Circulation; Coronary Vessels; Dogs; Heart Rate; Hemodynamics; Infusions, Intra-Arterial; Injections, Intra-Arterial; Myocardial Contraction; Parathyroid Hormone; Peptide Fragments; Phentolamine; Promethazine; Propranolol; Teriparatide

1985
Effects of locus coeruleus stimulation on carotid vascular resistance in the cat.
    Brain research, 1983, Nov-14, Volume: 278, Issue:1-2

    Topics: Animals; Atropine; Carotid Arteries; Cats; Cimetidine; Electric Stimulation; Female; Hexamethonium; Hexamethonium Compounds; Locus Coeruleus; Male; Phentolamine; Propranolol; Vagus Nerve; Vascular Resistance

1983
Alterations in intradental nerve responsiveness induced by electrical stimulation of the inferior alveolar nerve in the cat.
    Acta physiologica Scandinavica. Supplementum, 1983, Volume: 515

    Topics: Alveolar Process; Animals; Cats; Cimetidine; Dental Pulp; Electric Stimulation; Phentolamine; Pyrilamine; Sodium Chloride; Substance P; Trigeminal Nerve

1983
The involvement of central alpha-adrenergic and histamine H2-receptors in the hypothermia induced by clonidine in the rat.
    Neuropharmacology, 1980, Volume: 19, Issue:1

    Topics: Animals; Body Temperature; Cimetidine; Clonidine; Drug Interactions; Injections, Intraperitoneal; Injections, Intraventricular; Male; Phentolamine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Histamine; Receptors, Histamine H2; Time Factors

1980
Calcium channels resistant to organic calcium entry blockers in a rabbit vein.
    The American journal of physiology, 1983, Volume: 245, Issue:6

    Topics: Animals; Benzazepines; Calcium; Cimetidine; Diltiazem; Dose-Response Relationship, Drug; Face; Histamine; Ion Channels; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Phentolamine; Propranolol; Rabbits; Temperature; Veins; Verapamil

1983
Isolated human coronary arteries in response to vasoconstrictor substances.
    The American journal of physiology, 1983, Volume: 245, Issue:6

    Topics: Acetylcholine; Adult; Aged; Animals; Atropine; Chlorpheniramine; Cimetidine; Coronary Vessels; Epinephrine; Female; Histamine; Humans; Kinetics; Macaca; Male; Middle Aged; Norepinephrine; Phentolamine; Species Specificity; Vasoconstrictor Agents

1983
Action of dimethindene on the electrophysiological and mechanical properties of atrial and ventricular myocardium of guinea-pig.
    European journal of pharmacology, 1983, Dec-09, Volume: 96, Issue:1-2

    Topics: Action Potentials; Animals; Cimetidine; Dimethindene; Electrophysiology; Guinea Pigs; In Vitro Techniques; Muscles; Myocardial Contraction; Papillary Muscles; Phentolamine; Pindolol; Pyrilamine; Stimulation, Chemical

1983
Effects of drugs on the production of stress ulcer in the rat.
    Acta physiologica Academiae Scientiarum Hungaricae, 1982, Volume: 60, Issue:4

    Topics: Animals; Atropine; Cimetidine; Epoprostenol; Female; Male; Peptic Ulcer; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Stress, Physiological

1982
Effects of histamine on the resting and stimulation-induced release of [3H]-noradrenaline in guinea-pig isolated atria.
    British journal of pharmacology, 1982, Volume: 75, Issue:1

    Topics: Animals; Atropine; Cimetidine; Cocaine; Electric Stimulation; Female; Guinea Pigs; Heart Atria; Histamine; In Vitro Techniques; Indomethacin; Male; Myocardium; Norepinephrine; Phentolamine; Propranolol; Pyrilamine

1982
Isolated parietal cells: [3H]QNB binding to putative cholinergic receptors.
    The American journal of physiology, 1980, Volume: 239, Issue:3

    Topics: Animals; Atropine; Cell Separation; Cimetidine; Epinephrine; Female; Gastric Mucosa; Hexamethonium Compounds; Histamine; Neostigmine; Phentolamine; Physostigmine; Propranolol; Quinuclidines; Quinuclidinyl Benzilate; Rats; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine

1980
Proof for histaminergic but not for adrenergic involvement in the growth hormone-releasing effect of an enkephalin analog in the dog.
    Endocrinology, 1981, Volume: 108, Issue:1

    Topics: Animals; Cimetidine; Clemastine; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Diphenhydramine; Dogs; Endorphins; Enkephalins; Female; Glucose; Growth Hormone; Histamine; Male; Phentolamine; Propranolol; Sympathetic Nervous System

1981
Central mediation of tracheal pressure through H1 and H2 receptors after histamine administration to the fourth ventricle of anesthetized rabbit.
    Neuroscience letters, 1994, Mar-14, Volume: 169, Issue:1-2

    Topics: Animals; Atropine; Blood Pressure; Cimetidine; Histamine; Injections, Intraventricular; Phentolamine; Pressure; Pyrilamine; Rabbits; Receptors, Histamine H1; Receptors, Histamine H2; Trachea

1994
Thioperamide, a histamine H3-receptor blocker, facilitates vasopressor response to footshocks.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1998, Volume: 47, Issue:3

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cimetidine; Electric Stimulation; Enzyme Inhibitors; Heart Rate; Hindlimb; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Methylhistidines; Norepinephrine; Phentolamine; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Vasoconstrictor Agents

1998
Histamine H3 receptor-mediated suppression of inhibitory synaptic transmission in the submucous plexus of guinea-pig small intestine.
    European journal of pharmacology, 2000, May-26, Volume: 397, Issue:1

    Topics: Animals; Cimetidine; Dimaprit; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; In Vitro Techniques; Intestine, Small; Male; Methylhistamines; Norepinephrine; Phentolamine; Piperidines; Receptors, Histamine H3; Submucous Plexus; Synaptic Transmission

2000
Modulatory effects of taurine on jejunal contractility.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2014, Volume: 47, Issue:12

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Calcium Channel Blockers; Cimetidine; Diphenhydramine; Enteric Nervous System; Histamine H1 Antagonists; Histamine H2 Antagonists; Jejunum; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Myosin-Light-Chain Kinase; Myosins; Nitric Oxide; Nitric Oxide Synthase; Phentolamine; Phosphorylation; Propranolol; Rats, Sprague-Dawley; Taurine; Tetrodotoxin; Verapamil

2014