Page last updated: 2024-08-17

phentolamine and buspirone

phentolamine has been researched along with buspirone in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19902 (12.50)18.7374
1990's2 (12.50)18.2507
2000's2 (12.50)29.6817
2010's10 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
New, JS; Riblet, LA; Taylor, DP; Temple, DL; Yevich, JP1
Baldessarini, RJ; Booth, RG; Charifson, PS; Kula, NS; McPhail, AT; Myers, AM; Owens, CE; Wyrick, SD1
Berardi, F; Colabufo, NA; Leopoldo, M; Perrone, R; Tortorella, V1
Berardi, F; Colabufo, NA; Lacivita, E; Leonardi, A; Leopoldo, M; Perrone, R; Poggesi, E; Testa, R; Tortorella, V1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bojarski, AJ; Gunia, A; Marona, H; Pytka, K; Satała, G; Siwek, A; Szkaradek, N; Szneler, E; Waszkielewicz, AM1
Ashoor, A; Bojarski, AJ; Filipek, B; Handzlik, J; Kieć-Kononowicz, K; Kubacka, M; Kucwaj, K; Sadek, B; Satała, G; Siwek, A; Więcek, M1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Caliendo, G; Capasso, R; Ciano, A; Corvino, A; Di Vaio, P; Fiorino, F; Frecentese, F; Izzo, AA; Kędzierska, E; Kotlińska, JH; Magli, E; Massarelli, P; Orzelska-Gòrka, J; Perissutti, E; Rossi, I; Saccone, I; Santagada, V; Severino, B1
Handzlik, J; Jankowska, A; Jastrzębska-Więsek, M; Kieć-Kononowicz, K; Kucwaj-Brysz, K; Kurczab, R; Nitek, W; Partyka, A; Satała, G; Siwek, A; Wesołowska, A; Żesławska, E1

Reviews

1 review(s) available for phentolamine and buspirone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

15 other study(ies) available for phentolamine and buspirone

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Buspirone analogues. 1. Structure-activity relationships in a series of N-aryl- and heteroarylpiperazine derivatives.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Buspirone; Corpus Striatum; Kinetics; Male; Models, Molecular; Molecular Conformation; Piperazines; Pyrimidines; Rats; Receptors, Dopamine; Spiperone; Structure-Activity Relationship

1983
Conformational analysis, pharmacophore identification, and comparative molecular field analysis of ligands for the neuromodulatory sigma 3 receptor.
    Journal of medicinal chemistry, 1994, Nov-25, Volume: 37, Issue:24

    Topics: Animals; Ligands; Models, Molecular; Molecular Conformation; Receptors, sigma; Rodentia; Structure-Activity Relationship; Tetrahydronaphthalenes

1994
1-aryl-4-[(5-methoxy-1,2,3, 4-tetrahydronaphthalen-1-yl)alkyl]piperazines and their analogues: influence of the stereochemistry of the tetrahydronaphthalen-1-yl nucleus on 5-HT1A receptor affinity and selectivity versus alpha1 and D2 receptors. 5.
    Journal of medicinal chemistry, 1999, Feb-11, Volume: 42, Issue:3

    Topics: Animals; CHO Cells; Cricetinae; Gas Chromatography-Mass Spectrometry; Humans; Magnetic Resonance Spectroscopy; Piperazines; Radioligand Assay; Receptors, Adrenergic, alpha-1; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Stereoisomerism; Structure-Activity Relationship; Tetrahydronaphthalenes

1999
trans-4-[4-(Methoxyphenyl)cyclohexyl]-1-arylpiperazines: a new class of potent and selective 5-HT(1A) receptor ligands as conformationally constrained analogues of 4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]-1-arylpiperazines.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Animals; Brain; Ethylamines; Guanosine 5'-O-(3-Thiotriphosphate); HeLa Cells; Humans; In Vitro Techniques; Ligands; Molecular Conformation; Piperazines; Pyridines; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Stereoisomerism; Structure-Activity Relationship; Transfection

2001
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Synthesis and evaluation of pharmacological properties of some new xanthone derivatives with piperazine moiety.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Administration, Oral; Animals; Anticonvulsants; Drug Evaluation, Preclinical; Electroshock; Half-Life; Kinetics; Piperazine; Piperazines; Protein Binding; Rats; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Seizures; Xanthones

2013
SAR-studies on the importance of aromatic ring topologies in search for selective 5-HT(7) receptor ligands among phenylpiperazine hydantoin derivatives.
    European journal of medicinal chemistry, 2014, May-06, Volume: 78

    Topics: Dose-Response Relationship, Drug; Humans; Hydantoins; Ligands; Molecular Structure; Piperazines; Receptors, Serotonin; Structure-Activity Relationship

2014
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
New 5-HT
    Bioorganic & medicinal chemistry, 2017, 10-15, Volume: 25, Issue:20

    Topics: Animals; Binding Sites; Biological Assay; Ileum; Ligands; Maze Learning; Molecular Structure; Picolines; Protein Binding; Rats; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin Receptor Agonists

2017
Computer-aided insights into receptor-ligand interaction for novel 5-arylhydantoin derivatives as serotonin 5-HT
    European journal of medicinal chemistry, 2018, Mar-10, Volume: 147

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Computer-Aided Design; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Hydantoins; Male; Mice; Models, Molecular; Molecular Structure; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship

2018