phenserine has been researched along with tolserine in 5 studies
| Studies (phenserine) | Trials (phenserine) | Recent Studies (post-2010) (phenserine) | Studies (tolserine) | Trials (tolserine) | Recent Studies (post-2010) (tolserine) |
|---|---|---|---|---|---|
| 88 | 6 | 39 | 7 | 0 | 2 |
| Protein | Taxonomy | phenserine (IC50) | tolserine (IC50) |
|---|---|---|---|
| Cholinesterase | Homo sapiens (human) | 1.174 | |
| Acetylcholinesterase | Homo sapiens (human) | 0.4988 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brossi, A; Flippen-Anderson, JL; Greig, NH; Hoffman, B; Holloway, HW; Yu, Q | 1 |
| Brossi, A; Greig, NH; Holloway, HW; Whittaker, NF; Yu, QS; Zhu, X | 1 |
| Chaudhaery, SS; Nath, C; Nazir, A; Roy, KK; Sammi, SR; Saxena, AK; Saxena, G; Shakya, N | 1 |
| Li, X; Wang, S; Wang, Y; Wang, Z; Zhang, H | 1 |
| Al-Jafari, AA; Alhomida, AS; Greig, NH; Kamal, MA | 1 |
1 review(s) available for phenserine and tolserine
| Article | Year |
|---|---|
Recent advance on carbamate-based cholinesterase inhibitors as potential multifunctional agents against Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Humans; Ligands | 2022 |
4 other study(ies) available for phenserine and tolserine
| Article | Year |
|---|---|
Methyl analogues of the experimental Alzheimer drug phenserine: synthesis and structure/activity relationships for acetyl- and butyrylcholinesterase inhibitory action.
Topics: Acetylcholinesterase; Butyrylcholinesterase; Carbamates; Cholinesterase Inhibitors; Crystallography, X-Ray; Erythrocytes; Humans; Models, Molecular; Molecular Conformation; Physostigmine; Structure-Activity Relationship | 2001 |
Anticholinesterase activity of compounds related to geneserine tautomers. N-Oxides and 1,2-oxazines.
Topics: Acetylcholinesterase; Alkaloids; Butyrylcholinesterase; Cholinesterase Inhibitors; Cyclic N-Oxides; Humans; Isomerism; Oxazines; Structure-Activity Relationship | 2002 |
Novel carbamates as orally active acetylcholinesterase inhibitors found to improve scopolamine-induced cognition impairment: pharmacophore-based virtual screening, synthesis, and pharmacology.
Topics: Acetylcholinesterase; Administration, Oral; Animals; Avoidance Learning; Caenorhabditis elegans; Carbamates; Catalytic Domain; Cholinesterase Inhibitors; Databases, Factual; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Male; Mice; Models, Molecular; Nootropic Agents; Quantitative Structure-Activity Relationship; Scopolamine | 2010 |
Kinetics of human acetylcholinesterase inhibition by the novel experimental Alzheimer therapeutic agent, tolserine.
Topics: Acetylcholinesterase; Alzheimer Disease; Binding, Competitive; Cholinesterase Inhibitors; Humans; Kinetics; Physostigmine | 2000 |