phenserine has been researched along with physovenine in 4 studies
| Studies (phenserine) | Trials (phenserine) | Recent Studies (post-2010) (phenserine) | Studies (physovenine) | Trials (physovenine) | Recent Studies (post-2010) (physovenine) |
|---|---|---|---|---|---|
| 88 | 6 | 39 | 14 | 0 | 7 |
| Protein | Taxonomy | phenserine (IC50) | physovenine (IC50) |
|---|---|---|---|
| Cholinesterase | Homo sapiens (human) | 0.0067 | |
| Acetylcholinesterase | Homo sapiens (human) | 0.0155 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chaudhaery, SS; Nath, C; Nazir, A; Roy, KK; Sammi, SR; Saxena, AK; Saxena, G; Shakya, N | 1 |
| Li, X; Wang, S; Wang, Y; Wang, Z; Zhang, H | 1 |
| Brossi, A; Greig, NH; Ingram, DK; Pei, XF; Soncrant, TT | 1 |
| Barak, D; Greig, NH; Ordentlich, A; Shafferman, A; Stein, D; Yu, QS | 1 |
2 review(s) available for phenserine and physovenine
| Article | Year |
|---|---|
Recent advance on carbamate-based cholinesterase inhibitors as potential multifunctional agents against Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Humans; Ligands | 2022 |
Phenserine and ring C hetero-analogues: drug candidates for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Cholinesterase Inhibitors; Humans; Physostigmine; Rats; Structure-Activity Relationship | 1995 |
2 other study(ies) available for phenserine and physovenine
| Article | Year |
|---|---|
Novel carbamates as orally active acetylcholinesterase inhibitors found to improve scopolamine-induced cognition impairment: pharmacophore-based virtual screening, synthesis, and pharmacology.
Topics: Acetylcholinesterase; Administration, Oral; Animals; Avoidance Learning; Caenorhabditis elegans; Carbamates; Catalytic Domain; Cholinesterase Inhibitors; Databases, Factual; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Male; Mice; Models, Molecular; Nootropic Agents; Quantitative Structure-Activity Relationship; Scopolamine | 2010 |
Accommodation of physostigmine and its analogues by acetylcholinesterase is dominated by hydrophobic interactions.
Topics: Acetylcholinesterase; Binding Sites; Catalysis; Cholinesterase Inhibitors; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Models, Molecular; Molecular Structure; Mutation; Phenylcarbamates; Physostigmine; Protein Binding; Pyridostigmine Bromide; Rivastigmine; Structure-Activity Relationship | 2009 |