phenprocoumon has been researched along with proquazone* in 1 studies
1 trial(s) available for phenprocoumon and proquazone
Article | Year |
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On the interaction between the anti-inflammatory substance proquazone (RU 43-715) and phenprocoumone.
In a double blind study on 20 anticoagulated patients, the influence of the anti-inflammatory drug 1-isopropyl-4-phenyl-7-methyl-2 (1H) quinazolone on the degree of hypocoagulability was examined. In comparison to a placebo group, there was no statistical difference in the Quick precentage, in coagulation factors II, VII, and X, and in platelet aggregation induced by collagen and by epinephrine respectively. In addition, no increased bleeding tendency could be observed during the study. Topics: 4-Hydroxycoumarins; Adult; Aged; Anti-Inflammatory Agents; Blood Coagulation; Blood Coagulation Disorders; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Factor VII; Factor X; Female; Humans; Male; Middle Aged; Phenprocoumon; Placebos; Platelet Aggregation; Prothrombin; Quinazolines | 1977 |