phenoxybenzamine has been researched along with prazosin in 190 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 122 (64.21) | 18.7374 |
1990's | 50 (26.32) | 18.2507 |
2000's | 12 (6.32) | 29.6817 |
2010's | 6 (3.16) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
Bönisch, H; Brüss, M; Hayer-Zillgen, M | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Brouillette, WJ; Brown, GB; Zha, C | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Cavero, I; Fénard, S; Lefèvre, F | 1 |
Doxey, JC; Smith, CF; Walker, JM | 1 |
Cambridge, D; Davey, MJ; Massingham, R | 1 |
Charness, ME; Robertson, D; Snyder, SH; U'Prichard, DC | 1 |
Atkins, FL; Nicolosi, GL | 1 |
Commarato, MA; Dugan, DH; Kaplan, HR; Langley, AE; Lattime, EC; Smith, RD; Tessman, DK | 1 |
Dausse, J; Meyer, P; Miach, PJ | 1 |
Assous, E; Duteil, J; Gombert, R; Pessonnier, J; Rambert, FA | 1 |
Imhof, P | 1 |
Fuller, RW; Perry, KW; Snoddy, HD | 1 |
Baba, S; Kinami, J; Mano, F; Maruyama, K; Nagatomo, T; Tsuchihashi, H | 2 |
Doggrell, SA | 1 |
Bhandari, M; Kapoor, R; Kumar, A; Mishra, VK; Srivastava, A | 1 |
Drouva, SV; Faivre-Bauman, A; Kordon, C; Laplante, E; Loudes, C | 1 |
Badia, A; Sallés, J | 2 |
Göthert, M; Molderings, GJ | 1 |
Brien, JF; Marks, GS; Nakatsu, K; Pym, J; Witte, S | 1 |
Piascik, MT; Pruitt, TA; Soltis, EE; Sparks, MS | 1 |
Hsueh, W; Zhang, C | 1 |
Chandranath, SI; Gokhale, SD; Sharif, SI | 1 |
Ferrell, WR; Khoshbaten, A | 1 |
Boutros, AR; Bravo, EL; Straffon, RA; Zanettin, G | 1 |
Daly, CJ; Dunn, WR; McGrath, JC; Miller, DJ; Wilson, VG | 1 |
Endo, T; Hashimoto, K; Onaya, T; Shimura, H; Tsujimoto, G; Watanabe, K | 1 |
Guimarães, S; Moura, D; Vaz-da-Silva, MJ | 1 |
Bevan, JA; Oriowo, MA | 1 |
O'Rourke, ST; Vanhoutte, PM | 1 |
Campbell, MD; Deth, RC; Honeyman, TW; Payne, RA | 1 |
Bor, Y; Perrigot, M; Vannier, A | 1 |
Shanks, RG | 1 |
Caine, M | 1 |
Hester, RK; Satake, N; Shibata, S | 1 |
Bennett, GW; Fone, KC; Heal, DJ; Johnson, JV; Marsden, CA | 1 |
Horohonich, S; Ohlstein, EH; Ruffolo, RR; Shebuski, RJ | 1 |
Baum, BJ; Brown, AM; He, XJ; Wellner, RB; Wu, XZ | 1 |
Leighton, HJ; Ramagopal, MV | 1 |
Kusiak, JW; Piascik, MT; Pitha, J | 1 |
Bowersox, S; Ciaranello, R; Dement, WC; Frusthofer, B; Guilleminault, C; Maddaluno, J; Mignot, E; Nishino, S | 1 |
Feller, DR; Hamada, A; Miller, DD; Patil, PN; Shams, G; Venkataraman, BV | 1 |
Kenakin, TP; Novak, PJ | 1 |
Koike, K; Noguchi, R; Ogishima, M; Sato, T; Takayanagi, I; Takiguchi, F | 1 |
Holck, MI | 1 |
Babich, M; Butler, BT; Kusiak, JW; Le, HT; Piascik, MT; Pitha, J | 1 |
Hashimoto, K; Kato, K; Tsujimoto, A; Tsujimoto, G | 1 |
Kaufman, JM; Kesner, JS; Knobil, E; Wilson, RC | 1 |
Beyer, C; Fernández-Guasti, A; Larsson, K | 1 |
Evans, MH | 1 |
Furnace, G; Hamilton, CA; Reid, JL; Sumner, DJ | 1 |
Wein, AJ | 1 |
Campbell, IC; McKernan, RM | 2 |
Maher, TJ; Moya-Huff, FA | 1 |
Guimarães, S; Moura, D; Paiva, MQ | 1 |
Yuwiler, A | 1 |
Chiu, AT; Timmermans, PB; Wong, PC | 1 |
Galitzky, J; Paris, H; Taouis, M | 1 |
Dupont, C; Lacolle, JY; Poirier, M; Riffaud, JP | 1 |
Junnarkar, AY; Singh, PP | 1 |
Gonçalves, J; Guimarães, S; Nunes, JP; Paiva, MQ | 1 |
Endo, S; Iwai, R; Kamiyama, K; Nagahori, T; Ohtsuji, T; Takaku, A | 1 |
Endo, S; Iwai, R; Kamiyama, K; Otsuji, T; Sugita, T; Takaku, A | 1 |
Daly, CJ; Dunn, WR; McGrath, JC; Wilson, VG | 1 |
Gross, G; Hanft, G; Rugevics, CU | 1 |
Gherezghiher, T; Hey, JA; Koss, MC | 1 |
Alexander, RW; Brock, TA; Colucci, WS; Gimbrone, MA | 1 |
Pettinger, WA; Smyth, DD; Umemura, S | 2 |
Reny-Palasse, V; Rips, R | 1 |
Hamilton, CA; Reid, JL | 1 |
Brown, E; Kendall, DA; Nahorski, SR | 1 |
Jones, CE; Liang, IY; Maulsby, MR | 1 |
Legrand, C; Maltier, JP | 1 |
DiBona, GF; Koepke, JP | 1 |
Alexander, RW; Colucci, WS | 1 |
Talesnik, J; Youngson, BJ | 1 |
Azuma, T; Ohhashi, T | 1 |
Cornett, LE; Norris, JS | 1 |
Arendsen, DL; DeBernardis, JF; Kerkman, DJ; Kyncl, JJ; Winn, M | 1 |
Hölting, T; Starke, K | 1 |
Ishizuka, M; Koike, K; Maeda, O; Takayanagi, I | 1 |
Alosachie, I; Godfraind, T | 1 |
Hilakivi, IT; Mäkelä, JP | 1 |
Fowler, CJ; Thorell, G | 1 |
Bockaert, J; Bouhelal, R; Homburger, V; Mauger, JP; Mermet-Bouvier, R; Sladeczek, F | 1 |
Banuelos-Nevarez, A; Legrand, C; Maltier, JP; Rigolot, C | 1 |
Cahow, CE; Havlik, RJ; Kinder, BK | 1 |
Herr, DW; Tilson, HA | 1 |
Schwartz, PJ; Vanoli, E | 1 |
Horiguchi, Y; Kogi, K; Tani, T | 1 |
Scott, WJ; Ugen, KE | 1 |
Bevan, JA; Laher, I; Nishimura, S | 1 |
Kawabe, K | 1 |
Pulvirenti, L; Samanin, R | 1 |
Bouffioux, CR; Penders, L | 1 |
Freilich, JS; Greenberg, LH; Weiss, B; Zhou, LW | 1 |
Messick, K; Morgan, EL; Ruffolo, RR | 1 |
Cooke, JP; Flavahan, NA; Rimele, TJ; Vanhoutte, PM | 1 |
Amitai, G; Brown, RD; Taylor, P | 1 |
Ambler, SK; Brown, RD; Taylor, P | 1 |
Dean, RR; Waterbury, LD | 1 |
Gomes, C; Henning, M; Persson, B; Trolin, G | 1 |
Anderson, S; Blomqvist, CG; Gaffney, F; Graham, RM; Muckleroy, C; Mulvihill-Wilson, J; Pettinger, WA | 1 |
Hattori, Y; Kanno, M | 1 |
Hamilton, CA; Hannah, JA; Reid, JL | 1 |
Seideman, P | 1 |
Andrews, K; Kiruluta, HG | 1 |
Birkenhäger, WH; De Leeuw, PW | 1 |
Kirpekar, SM | 1 |
Casanueva, CR; Castilla, C; García-Sacristán, A; Labadia, A | 1 |
Alexander, RW; Braunwald, E; Colucci, WS; Williams, GH | 1 |
Graham, RM; Pettinger, WA; Stephenson, WH | 1 |
Felix, W; Greif, J | 1 |
Davey, MJ | 1 |
Kato, R; Nakadate, T; Nakaki, T | 1 |
Constantine, JW; Lebel, W | 1 |
Blair, ML | 1 |
Borsodi, A; Ferry, N; Geynet, P; Hanoune, J | 1 |
Constantine, JW; Docherty, JR; Starke, K | 1 |
Bockaert, J; Mauger, JP; Sladeczek, F | 1 |
Fagbemi, SO; Salako, LA | 1 |
Insel, PA; Motulsky, HJ | 1 |
Greguski, R; Kan, WH; Kunos, G; Venter, JC | 1 |
Bockaert, J; Sladeczek, F | 1 |
Deth, RC; Lynch, CJ; Steer, ML | 1 |
Górka, Z; Maj, J; Melzacka, M; Pilc, A; Rawłów, A | 1 |
Suzuki, H | 1 |
Bond, RF; Johnson, G | 1 |
Dalrymple, HW; Hamilton, CA; Reid, JL; Sumner, DJ | 1 |
Fowler, PJ; Grous, M; Matthews, WD; Price, W | 1 |
Asano, Y; Imai, M; Kusano, E; Nakamura, R | 1 |
Caron, MG; DeMarinis, RM; Lefkowitz, RJ; Regan, JW | 1 |
Goldberg, MR; Morgan, EL; Ruffolo, RR | 1 |
Ichihara, A; Kato, S; Nakamura, T | 1 |
Koepke, JP; Light, KC; Morris, M; Obrist, PA | 1 |
Feder, HH; Nock, B | 1 |
Horton, R; Nadler, J; Zipser, RD | 1 |
Strandgaard, S | 1 |
Fitzgerald, GA; Knapp, HR | 1 |
Hu, XQ; Zhang, L | 1 |
Amobi, NI; Smith, IC | 1 |
Breslin, D; Chou, TC; Felsen, D; Fields, DW; Kane, M; Marion, DN; Vaughan, ED | 1 |
Brawer, MK | 1 |
Lepor, H | 1 |
Blaylock, NA; Wilson, VG | 1 |
Banerjee, GK; Bhandari, M; Goel, MC; Kapoor, R; Kumar, A; Mishra, VK | 1 |
Marwood, JF | 1 |
Olson, KR; Xu, HY | 1 |
Kennedy, RH; Lindemann, JP; Seifen, E; Stimers, JR; Williamson, AP | 1 |
Kigoshi, S; Muramatsu, I; Oshita, M | 1 |
Abe, K; Hidaka, S; Okina, A; Tashiro, M | 1 |
Badia, A; Gascón, S; Ivorra, D; Sallés, J | 1 |
Azuma, H | 1 |
Gherezghiher, T; Koss, MC | 1 |
Edwall, L; Funato, A; Kerezoudis, NP; Olgart, L | 1 |
Docherty, JR; Kearns, S; O'Rourke, M | 1 |
Goodman, RL; Havern, RL; Whisnant, CS | 1 |
Boulanger, CM; Illiano, S; Marsault, R; Taddei, S; Vanhoutte, PM | 1 |
Badia, A; Giraldo, J; Tabernero, A; Vila, E; Vivas, NM | 1 |
Badia, A; Gascón, S; Sallés, J | 1 |
Malik, KU; Ruan, Y; Sehic, E | 1 |
Bransome, ED; Carr, AA; Prisant, LM; Steinsapir, J | 1 |
Fernández Arjona, M; Fernández Borrell, A; Gómez Sancha, F; Mínguez Martínez, R; Peinado Ibarra, F; Pereira Sanz, I | 1 |
Frewin, DB; Metcalfe, IR; Russell, WJ; Tonkin, AL | 1 |
Rossi, NF | 1 |
Daniel, EE; Kwan, CY; Loke, JC; Low, AM; Lu-Chao, H | 1 |
Amobi, N; Coker, C; Guillebaud, J; Mulvin, D; Smith, IC | 1 |
Fedida, D; Li, Q; Parker, C | 1 |
Avellar, MC; Megale, A; Porto, CS; Silva, MA | 1 |
Gogoi, S; Kumar, A; Mandhani, A; Srivastava, A | 1 |
Eckert, RE; Karsten, AJ; Utz, J; Ziegler, M | 1 |
Kawarai, M; Koss, MC | 1 |
Kawatani, M; Sato, M | 1 |
Miranda, HF; Pinardi, G; Sierralta, F | 1 |
Cribb, AE; Fischer, JR; Lane, IF | 1 |
Amobi, N; Guillebaud, J; Kaisary, A; Lloyd-Davies, RW; Smith, IC; Turner, E | 1 |
Koss, MC; Yu, Y | 2 |
Hou, SK; Liu, SJ; Wang, XF; Wang, YC; Xu, KX | 1 |
Gutkowska, J; Menaouar, A; Mukaddam-Daher, S | 1 |
Schally, AV; Telegdy, G | 1 |
Agarwal, A; Agarwal, G; Agrawal, R; Bhatia, E; Chand, G; Mishra, A; Mishra, SK; Verma, AK | 1 |
Bagosi, Z; Jászberényi, M; Palotai, M; Tanaka, M; Telegdy, G | 1 |
12 review(s) available for phenoxybenzamine and prazosin
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Treatment of cardiac failure with vasodilators (author's transl)].
Topics: Cardiac Glycosides; Diuretics; Drug Therapy, Combination; Heart Failure; Hydralazine; Hypotension; Isosorbide Dinitrate; Nitroglycerin; Nitroprusside; Phenoxybenzamine; Phentolamine; Prazosin; Vasodilator Agents | 1978 |
Alpha-adrenergic mechanisms in dynamics of benign prostatic hypertrophy.
Topics: Adrenergic alpha-Antagonists; Humans; Male; Phenoxybenzamine; Prazosin; Prostate; Prostatic Hyperplasia; Receptors, Adrenergic, alpha | 1988 |
Pharmacologic treatment of lower urinary tract dysfunction in the female patient.
Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Bethanechol; Bethanechol Compounds; Drug Therapy, Combination; Female; Humans; Imipramine; Male; Muscle Relaxants, Central; Muscle, Smooth; Parasympatholytics; Phenoxybenzamine; Prazosin; Receptors, Adrenergic; Urethra; Urinary Bladder; Urinary Bladder Diseases; Urinary Bladder Neck Obstruction; Urination Disorders; Urologic Diseases | 1985 |
Alpha-blockers in the treatment of benign prostatic hypertrophy: physiological basis and review of the problem.
Topics: Adrenergic alpha-Antagonists; Clinical Trials as Topic; Double-Blind Method; Humans; Labetalol; Male; Phenoxybenzamine; Phentolamine; Prazosin; Prostatic Hyperplasia; Receptors, Adrenergic, alpha | 1984 |
Pharmacokinetic and dynamic aspects of alpha-adrenoceptor blockade in hypertension.
Topics: Adrenergic alpha-Antagonists; Animals; Biological Availability; Blood Proteins; Brain; Dose-Response Relationship, Drug; Drug Interactions; Humans; Hypertension; Kinetics; Phenoxybenzamine; Phentolamine; Prazosin; Protein Binding; Substance Withdrawal Syndrome | 1982 |
Alpha-adrenergic blockade in the treatment of essential hypertension.
Topics: Adrenergic alpha-Antagonists; Biomechanical Phenomena; Hemodynamics; Humans; Hypertension; Indoramin; Labetalol; Phenoxybenzamine; Prazosin; Receptors, Adrenergic, alpha | 1983 |
Support for a role for feedback regulation of norepinephrine release.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Cocaine; Cystamine; Diethylamines; Drug Synergism; Electric Stimulation; Ephedrine; Feedback; Naphthalenes; Norepinephrine; Phenoxybenzamine; Phentolamine; Prazosin; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Synaptic Membranes | 1984 |
Mechanisms and implications of vasodilator tolerance in the treatment of congestive heart failure.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Angiotensin-Converting Enzyme Inhibitors; Drug Tolerance; Enzyme Inhibitors; Heart Failure; Humans; Hydralazine; Nitrates; Nitroprusside; Oligopeptides; Parasympatholytics; Phenoxybenzamine; Phentolamine; Prazosin; Teprotide; Vasodilator Agents | 1981 |
The role of alpha 1-blockade in benign prostatic hyperplasia.
Topics: Adrenergic alpha-Antagonists; Aging; Clinical Trials as Topic; Humans; Male; Phenoxybenzamine; Prazosin; Prostatectomy; Prostatic Hyperplasia | 1993 |
Medical therapy for benign prostatic hyperplasia.
Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Androgen Antagonists; Anilides; Clinical Trials as Topic; Humans; Male; Nitriles; Phenoxybenzamine; Prazosin; Prostatic Hyperplasia; Tosyl Compounds | 1993 |
[Alpha blockers in the treatment of benign hyperplasia of the prostate].
Topics: Adrenergic alpha-Antagonists; Doxazosin; Humans; Indoramin; Male; Phenoxybenzamine; Prazosin; Prostatic Hyperplasia; Quinazolines; Sulfonamides; Tamsulosin | 1997 |
3 trial(s) available for phenoxybenzamine and prazosin
Article | Year |
---|---|
Alpha-blockers in the treatment of benign prostatic hypertrophy: physiological basis and review of the problem.
Topics: Adrenergic alpha-Antagonists; Clinical Trials as Topic; Double-Blind Method; Humans; Labetalol; Male; Phenoxybenzamine; Phentolamine; Prazosin; Prostatic Hyperplasia; Receptors, Adrenergic, alpha | 1984 |
[Comparison of the effects of prazosin and phenoxybenzamine on arterial pressure, heart rate and plasma catecolamines in essential arterial hypertension].
Topics: Adrenergic alpha-Antagonists; Adult; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Epinephrine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Phenoxybenzamine; Prazosin; Quinazolines; Random Allocation | 1980 |
Prospective study to compare peri-operative hemodynamic alterations following preparation for pheochromocytoma surgery by phenoxybenzamine or prazosin.
Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Adult; Blood Pressure; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Hypotension; Intraoperative Complications; Male; Middle Aged; Phenoxybenzamine; Pheochromocytoma; Prazosin; Preoperative Care; Prospective Studies; Treatment Outcome | 2014 |
176 other study(ies) available for phenoxybenzamine and prazosin
Article | Year |
---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Expression and pharmacological profile of the human organic cation transporters hOCT1, hOCT2 and hOCT3.
Topics: Analysis of Variance; Cations; Cell Line; Cloning, Molecular; Humans; Ion Transport; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Reverse Transcriptase Polymerase Chain Reaction; Transfection | 2002 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels | 2014 |
Vascular beta-adrenoceptor stimulating properties of phenylephrine.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Blood Pressure; Cyclopropanes; Drug Interactions; Imidazoles; Isoproterenol; Norepinephrine; Phenoxybenzamine; Phenylephrine; Prazosin; Propranolol; Rats; Stimulation, Chemical; Vasomotor System | 1977 |
Selectivity of blocking agents for pre-and postsynaptic alpha-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenoxybenzamine; Phentolamine; Prazosin; Rats; Synapses; Vas Deferens; Yohimbine | 1977 |
The pharmacology of antihypertensive drugs with special reference to vasodilators, alpha-adrenergic blocking agents and prazosin.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Carotid Sinus; Dogs; Epinephrine; Humans; Hypertension; In Vitro Techniques; Norepinephrine; Phenoxybenzamine; Prazosin; Pulmonary Artery; Quinazolines; Rabbits; Receptors, Adrenergic, alpha; Renin; Vasodilator Agents | 1977 |
Prazosin: differential affinities for two populations of alpha-noradrenergic receptor binding sites.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dihydroergotoxine; In Vitro Techniques; Male; Phenoxybenzamine; Phentolamine; Prazosin; Quinazolines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1978 |
Alpha-adrenergic blocking activity of prazosin. Effect on catecholamine levels and catecholamine synthetic enzymes.
Topics: Adrenal Glands; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Dopamine beta-Hydroxylase; Heart Rate; Male; Myocardium; Norepinephrine; Phenoxybenzamine; Prazosin; Quinazolines; Rats; Time Factors; Tyrosine 3-Monooxygenase | 1979 |
Prazosin and phentolamine: comparative cardiovascular and autonomic profiles.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Denervation; Dogs; Female; Guinea Pigs; Heart; In Vitro Techniques; Leg; Male; Phenoxybenzamine; Phentolamine; Prazosin; Quinazolines; Rats; Sympathetic Nervous System; Vasodilator Agents | 1978 |
Direct biochemical demonstration of two types of alpha-adrenoreceptor in rat brain.
Topics: Animals; Binding, Competitive; Brain; Clonidine; Dihydroergotoxine; Dopamine; Male; Phenoxybenzamine; Phentolamine; Piperoxan; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Synaptic Membranes; Yohimbine | 1978 |
A possibe alpha-adrenergic mechanism for drug (CRL 40028)-induced hyperactivity.
Topics: Animals; Benzhydryl Compounds; Dose-Response Relationship, Drug; Hydroxamic Acids; Male; Mice; Motor Activity; Phenoxybenzamine; Prazosin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1979 |
Effect of prazosin on norepinephrine concentration and turnover in rat brain and heart.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Male; Metaraminol; Methoxyhydroxyphenylglycol; Myocardium; Norepinephrine; Phenoxybenzamine; Prazosin; Quinazolines; Rats | 1978 |
Alpha 1-adrenoceptor subtypes in the rat ventricular muscle.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Heart Ventricles; Kinetics; Male; Myocardium; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Regression Analysis | 1992 |
An analysis of the inhibitory effects of prazosin on the phenylephrine response curves of the rat aorta.
Topics: Animals; Aorta, Thoracic; Endothelium, Vascular; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenoxybenzamine; Phentolamine; Phenylephrine; Prazosin; Rats; Rats, Wistar | 1992 |
Functional bladder neck obstruction in males: a progressive disorder?
Topics: Adolescent; Adult; Catheters, Indwelling; Child; Electromyography; Humans; Male; Middle Aged; Phenoxybenzamine; Prazosin; Urinary Bladder; Urinary Bladder Neck Obstruction; Urinary Catheterization; Urodynamics | 1992 |
Alpha 1-adrenergic receptor coupling with phospholipase-C is negatively regulated by protein kinase-C in primary cultures of hypothalamic neurons and glial cells.
Topics: Animals; Astrocytes; Calcium Channels; Cell Membrane; Cells, Cultured; Chromatography, Ion Exchange; Clonidine; Diglycerides; Feedback; GTP-Binding Proteins; Hypothalamus; Inositol Phosphates; Kinetics; Membrane Lipids; Mice; Neurons; Norepinephrine; Phenoxybenzamine; Phosphatidylinositols; Prazosin; Propranolol; Protein Kinase C; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Type C Phospholipases; Yohimbine | 1991 |
Mechanisms underlying the differential sensitivity to alpha 1-adrenoceptor activation in the bisected rat vas deferens.
Topics: Adrenergic alpha-Agonists; Animals; Binding, Competitive; In Vitro Techniques; Kinetics; Male; Phenoxybenzamine; Prazosin; Rats; Receptors, Adrenergic, alpha; Vas Deferens | 1991 |
Involvement of presynaptic imidazoline receptors in the alpha 2-adrenoceptor-independent inhibition of noradrenaline release by imidazoline derivatives.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Drug Interactions; Electric Stimulation; Imidazoles; Imidazoline Receptors; Isoindoles; Male; Norepinephrine; Phenoxybenzamine; Phentolamine; Prazosin; Pulmonary Artery; Rabbits; Receptors, Drug; Receptors, Neurotransmitter; Tritium; Yohimbine | 1991 |
Adrenoceptors of the human internal thoracic artery.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Clonidine; Dinoprostone; Humans; In Vitro Techniques; Isometric Contraction; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Phenylephrine; Prazosin; Receptors, Adrenergic; Serotonin; Thoracic Arteries; Yohimbine | 1991 |
Evidence for a complex interaction between the subtypes of the alpha 1-adrenoceptor.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Clonidine; Dioxanes; In Vitro Techniques; Kinetics; Male; Methoxamine; Muscle, Smooth, Vascular; Phenoxybenzamine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1991 |
Comparison of alpha 1-adrenoceptors between rat brain and spleen.
Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Brain; Dibenzylchlorethamine; Kinetics; Male; Phenoxybenzamine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Spleen | 1991 |
PAF-induced bowel necrosis. Effects of vasodilators.
Topics: Alprostadil; Animals; Hydralazine; Hypotension; Indazoles; Intestinal Diseases; Leukopenia; Male; Mesenteric Arteries; Necrosis; Nitroglycerin; Phenoxybenzamine; Platelet Activating Factor; Prazosin; Rats; Rats, Inbred Strains; SRS-A; Vasodilator Agents | 1991 |
Pharmacological characterization of the postjunctional alpha-adrenoceptors of the rat isolated seminal vesicle.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Male; Naphazoline; Norepinephrine; Oxymetazoline; Phenoxybenzamine; Phentolamine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Seminal Vesicles; Yohimbine | 1990 |
Responses of blood vessels in the rabbit knee to electrical stimulation of the joint capsule.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Female; Guanethidine; In Vitro Techniques; Knee Joint; Male; Neurotransmitter Agents; Phenoxybenzamine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Receptors, Purinergic; Vasoconstriction | 1990 |
Perioperative management of 63 patients with pheochromocytoma.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Evaluation Studies as Topic; Female; Humans; Intraoperative Care; Male; Middle Aged; Nitroglycerin; Nitroprusside; Phenoxybenzamine; Pheochromocytoma; Prazosin; Premedication; Preoperative Care; Retrospective Studies | 1990 |
An examination of the sources of calcium for contractions mediated by postjunctional alpha 1- and alpha 2-adrenoceptors in several blood vessels isolated from the rabbit.
Topics: Animals; Calcium; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Potassium Chloride; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Saphenous Vein; Veins; Yohimbine | 1990 |
Characterization of alpha 1-adrenergic receptor subtypes linked to iodide efflux in rat FRTL cells.
Topics: Animals; Calcium; Cells, Cultured; Clonidine; Dose-Response Relationship, Drug; Iodides; Norepinephrine; Phenoxybenzamine; Prazosin; Rats; Receptors, Adrenergic, alpha; Thyroid Gland; Time Factors | 1990 |
Alpha-adrenoceptor reserve in the canine cephalic vein.
Topics: Animals; Brimonidine Tartrate; Dogs; Dose-Response Relationship, Drug; Female; Forelimb; Male; Phenoxybenzamine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Vasoconstriction; Veins; Yohimbine | 1990 |
Chloroethylclonidine unmasks a non-alpha-adrenoceptor noradrenaline binding site in the rat aorta.
Topics: Animals; Aorta, Thoracic; Clonidine; Dioxanes; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Prazosin; Rats; Receptors, Adrenergic; Yohimbine | 1990 |
Adrenergic and cholinergic responsiveness of isolated canine bronchial arteries.
Topics: Acetylcholine; Animals; Atropine; Bronchial Arteries; Dinoprost; Dogs; Electric Stimulation; Endothelium, Vascular; Female; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Parasympathetic Nervous System; Phenoxybenzamine; Phentolamine; Prazosin; Regional Blood Flow; Sympathetic Nervous System; Tetrodotoxin; Tyramine | 1990 |
Phosphoinositide hydrolysis is correlated with agonist-induced calcium flux and contraction in the rabbit aorta.
Topics: Animals; Aorta; Calcium; Female; Hydrolysis; In Vitro Techniques; Ion Channels; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Phosphatidylinositols; Prazosin; Rabbits; Yohimbine | 1985 |
[Alpha adrenergic blocking agents in disorders of the bladder sphincter].
Topics: Adrenergic alpha-Antagonists; Adult; Female; Humans; Male; Moxisylyte; Nicergoline; Phenoxybenzamine; Prazosin; Prostatic Hyperplasia; Urinary Bladder Neck Obstruction; Urinary Bladder, Neurogenic; Urinary Incontinence; Urination Disorders | 1986 |
The clinical pharmacology of indoramin.
Topics: Blood Pressure; Heart Rate; Humans; Hypertension; Indoles; Indoramin; Kinetics; Norepinephrine; Phenoxybenzamine; Phenylephrine; Posture; Prazosin; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1986 |
Differential inhibitory effects of nitroglycerin on contractile responses to the alpha-adrenoceptor agonists, methoxamine and clonidine, in rabbit aorta.
Topics: Adrenergic alpha-Agonists; Animals; Calcium; Calcium Radioisotopes; Clonidine; Egtazic Acid; In Vitro Techniques; Lanthanum; Male; Methoxamine; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitroglycerin; Phenoxybenzamine; Potassium; Prazosin; Rabbits; Yohimbine | 1989 |
TRH-catecholamine interactions in brain and spinal cord.
Topics: Animals; Catecholamines; Cerebral Ventricles; Clonidine; Fluoxetine; Hypothalamus; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Motor Activity; Norepinephrine; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred Strains; Reference Values; Spinal Cord; Stereotyped Behavior; Thyrotropin-Releasing Hormone | 1989 |
Localization and characterization of alpha-2 adrenoceptors in the isolated canine pulmonary vein.
Topics: Animals; Azepines; Dogs; Dose-Response Relationship, Drug; In Vitro Techniques; Phenoxybenzamine; Prazosin; Pulmonary Veins; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine | 1989 |
Characteristics of alpha 1-adrenergic receptors in a rat salivary cell line, RSMT-A5.
Topics: Animals; Cell Line; Cell Membrane; Inositol; Phenoxybenzamine; Phosphatidylinositols; Prazosin; Protein Binding; Proteins; Rats; Receptors, Adrenergic, alpha; Salivary Glands | 1989 |
Analysis of the presence of postjunctional alpha-2 adrenoceptors in the rat anococcygeus muscle.
Topics: Animals; Clonidine; Dioxanes; Electric Stimulation; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Phenoxybenzamine; Prazosin; Rats; Receptors, Adrenergic, alpha; Regression Analysis | 1989 |
Interaction of a chemically reactive prazosin analog with alpha-1 adrenoceptors of rat tissues.
Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Dose-Response Relationship, Drug; Male; Phenoxybenzamine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1989 |
Central alpha 1 adrenoceptor subtypes in narcolepsy-cataplexy: a disorder of REM sleep.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Cataplexy; Clonidine; Dioxanes; Dogs; Narcolepsy; Phenoxybenzamine; Prazosin; Receptors, Adrenergic, alpha; Sleep, REM | 1989 |
Paradoxical effects of isothiocyanate analog of tolazoline on rat aorta and human platelets.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Atrial Function; Benzazepines; Blood Platelets; Calcium; Carbachol; Dose-Response Relationship, Drug; Epinephrine; Female; Guinea Pigs; Heart Atria; Isoproterenol; Isothiocyanates; Male; Nifedipine; Phenoxybenzamine; Phentolamine; Phenylephrine; Platelet Activation; Platelet Aggregation; Prazosin; Rats; Rats, Inbred Strains; Temperature; Thiocyanates; Tolazoline; Trachea; Vasoconstriction; Verapamil; Yohimbine | 1989 |
Classification of phenoxybenzamine/prazosin-resistant contractions of rat spleen to norepinephrine by Schild analysis: similarities and differences to postsynaptic alpha-2 adrenoceptors.
Topics: Alkylation; Animals; Dioxanes; Drug Resistance; Idazoxan; Male; Muscle Contraction; Norepinephrine; Phenoxybenzamine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Spleen; Yohimbine | 1988 |
A regional difference in alpha 1-adrenoceptor mechanism in canine veins.
Topics: Animals; Binding, Competitive; Dogs; Female; In Vitro Techniques; Male; Microsomes; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Prazosin; Receptors, Adrenergic, alpha; Vasoconstriction; Veins | 1987 |
Alpha 1-adrenoceptor reserve and effects of a Ca2+ entry blocker (Ro 18-3981) on aorta of spontaneously hypertensive rats.
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Dihydropyridines; In Vitro Techniques; Male; Norepinephrine; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine | 1988 |
Alkylation of alpha-1 receptors with a chemically reactive analog of prazosin reveals low affinity sites for norepinephrine in rabbit aorta.
Topics: Alkylation; Animals; Dose-Response Relationship, Drug; Microsomes; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
In vivo desensitization of glycogenolysis to Ca2+-mobilizing hormones in rat liver cells.
Topics: Adrenal Gland Neoplasms; Angiotensin II; Animals; Arginine Vasopressin; Bucladesine; Calcimycin; Calcium; Colforsin; Glucagon; Hormones; Liver Glycogen; Male; Norepinephrine; Phenoxybenzamine; Phenylephrine; Pheochromocytoma; Phosphorylases; Prazosin; Rats; Receptors, Adrenergic, alpha; Second Messenger Systems | 1988 |
Electrophysiological manifestation of luteinizing hormone-releasing hormone pulse generator activity in the rhesus monkey: influence of alpha-adrenergic and dopaminergic blocking agents.
Topics: Adrenergic alpha-Antagonists; Animals; Dopamine Antagonists; Electrophysiology; Female; Gonadotropin-Releasing Hormone; Macaca; Macaca mulatta; Metoclopramide; Phenoxybenzamine; Phentolamine; Prazosin; Yohimbine | 1985 |
Prevention of progesterone-induced lordosis behavior by alpha or beta adrenergic antagonists in ovariectomized estrogen-primed rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Castration; Estradiol; Estrogens; Female; Phenoxybenzamine; Posture; Prazosin; Progesterone; Propranolol; Rats; Rats, Inbred Strains; Sexual Behavior, Animal | 1985 |
Effects of some alpha-adrenoceptor antagonists on central cardio-decelerator mechanisms in the rabbit.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Brain Stem; Female; Heart Rate; Hypothalamus, Posterior; Injections, Intravenous; Injections, Intraventricular; Male; Neurons, Afferent; Phenoxybenzamine; Prazosin; Pressoreceptors; Rabbits; Reflex; Time Factors; Yohimbine | 1985 |
Recovery of alpha-adrenoreceptor mediated responses and binding site number after intravenous benextramine in the rabbit.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Brain; Clonidine; Cystamine; Injections, Intravenous; Male; Membranes; Phenoxybenzamine; Phenylephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Spleen; Time Factors | 1985 |
Phenoxybenzamine partially inhibits alpha 2-adrenoceptors without affecting their presynaptic function.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Clonidine; In Vitro Techniques; Male; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Adrenergic receptor subtype activation by (+)-, (-)- and (+/-)-norephedrine in the pithed rat.
Topics: Animals; Blood Pressure; Cardiovascular System; Decerebrate State; Heart Rate; Isomerism; Male; Phenoxybenzamine; Phenylpropanolamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reserpine; Vasoconstriction; Yohimbine | 1987 |
Alpha 2-adrenoceptor-mediated responses to so-called selective alpha 1-adrenoceptor agonists after partial blockade of alpha 1-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Dogs; Drug Interactions; In Vitro Techniques; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Phenoxybenzamine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Verapamil; Yohimbine | 1987 |
Synergistic action of postsynaptic alpha-adrenergic receptor stimulation on vasoactive intestinal polypeptide-induced increases in pineal N-acetyltransferase activity.
Topics: Acetyltransferases; Adrenergic alpha-Agonists; Animals; Arylamine N-Acetyltransferase; Atenolol; Clonidine; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Male; Methoxamine; Phenoxybenzamine; Phentolamine; Phenylephrine; Pineal Gland; Prazosin; Propranolol; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide; Yohimbine | 1987 |
Alpha-1 adrenoceptor-induced Ca++ movements in rat aorta: antagonism by phenoxybenzamine and N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Calcium; Dose-Response Relationship, Drug; Male; Nifedipine; Phenoxybenzamine; Potassium; Prazosin; Quinolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoconstriction | 1987 |
In vitro study of alpha 2-adrenoceptor turnover and metabolism using the adenocarcinoma cell line HT29.
Topics: Adenocarcinoma; Adenylyl Cyclases; Adrenergic alpha-Antagonists; Animals; Cell Line; Cell Membrane; Colonic Neoplasms; Cyclic AMP; Cystamine; Kinetics; Phenoxybenzamine; Prazosin; Receptors, Adrenergic, alpha; Yohimbine | 1987 |
Effects of five alpha-blockers on the hypogastric nerve stimulation of the canine lower urinary tract.
Topics: Adrenergic alpha-Antagonists; Animals; Dogs; Electric Stimulation; Hypogastric Plexus; Male; Moxisylyte; Phenoxybenzamine; Phentolamine; Prazosin; Pressure; Receptors, Adrenergic, alpha; Urethra; Urinary Bladder; Urination Disorders; Yohimbine | 1988 |
Antagonism of clonidine-induced hypothermia by alpha adrenoceptor antagonists in electrically stimulated mice.
Topics: Adrenergic alpha-Antagonists; Animals; Body Temperature; Clonidine; Electroshock; Fever; Male; Mice; Mice, Inbred Strains; Phenoxybenzamine; Prazosin; Yeasts; Yohimbine | 1988 |
Loss of selectivity of so-called selective alpha 1-adrenoceptor agonists after phenoxybenzamine.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Brimonidine Tartrate; Dogs; Dose-Response Relationship, Drug; Female; Imidazoles; Male; Phenoxybenzamine; Phenylephrine; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
Relation of supersensitivity to cerebral vasospasm induced by oxyhaemoglobin.
Topics: Animals; Basilar Artery; Cats; Ganglia, Sympathetic; Ischemic Attack, Transient; Oxyhemoglobins; Phenoxybenzamine; Prazosin; Receptors, Adrenergic, alpha; Sympathectomy; Vasoconstriction | 1988 |
[Experimental cerebral vasospasm induced by oxyhemoglobin and the sympathetic nervous system (Part 1): Effect of alpha-adrenergic receptor blockers].
Topics: Adrenergic alpha-Antagonists; Animals; Cats; Cerebrovascular Circulation; Dinoprost; Ischemic Attack, Transient; Norepinephrine; Oxyhemoglobins; Phenoxybenzamine; Prazosin; Sympathetic Nervous System; Vasomotor System | 1988 |
An attempt at selective protection from phenoxybenzamine of postjunctional alpha-adrenoceptor subtypes mediating contractions to noradrenaline in the rabbit isolated saphenous vein.
Topics: Adrenergic alpha-Antagonists; Animals; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Saphenous Vein; Sulfonamides; Yohimbine | 1988 |
Alpha 1-adrenoceptors of rat myocardium: comparison of agonist binding and positive inotropic response.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dose-Response Relationship, Drug; Male; Myocardial Contraction; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reserpine; Stimulation, Chemical; Temperature | 1988 |
Atypical alpha-adrenoceptor mediates phenylephrine-induced mydriasis in anesthetized cats.
Topics: Adrenergic alpha-Antagonists; Animals; Cats; Dioxanes; Dose-Response Relationship, Drug; Female; Infusions, Intravenous; Male; Mydriatics; Nictitating Membrane; Phenoxybenzamine; Phenylephrine; Prazosin; Pupil; Receptors, Adrenergic, alpha | 1988 |
Nonlinear relationship between alpha 1-adrenergic receptor occupancy and norepinephrine-stimulated calcium flux in cultured vascular smooth muscle cells.
Topics: Animals; Aorta; Calcium; Cells, Cultured; Male; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Tritium | 1985 |
Renal nerve stimulation causes alpha 1-adrenoceptor-mediated sodium retention but not alpha 2-adrenoceptor antagonism of vasopressin.
Topics: Animals; Body Water; Cyclic AMP; Electric Stimulation; Epinephrine; Kidney; Male; Natriuresis; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Regional Blood Flow; Vasopressins; Yohimbine | 1985 |
Potentiation by TRH of the effect of imipramine on the forced-swimming test.
Topics: Animals; Drug Synergism; Drug Tolerance; Imipramine; Male; Mice; Morphine; Naloxone; Phenoxybenzamine; Phentolamine; Prazosin; Receptors, Adrenergic, alpha; Receptors, Opioid; Swimming; Thyrotropin-Releasing Hormone; Yohimbine | 1985 |
The effects of phenoxybenzamine on specific binding and function of central alpha-adrenoceptors in the rabbit.
Topics: Animals; Brain; Clonidine; Dactinomycin; Drug Interactions; Fluorouracil; Male; Phenoxybenzamine; Prazosin; Rabbits; Receptors, Adrenergic, alpha | 1985 |
Alpha 1-adrenoceptor-mediated inositol phospholipid hydrolysis in rat cerebral cortex: relationship between receptor occupancy and response and effects of denervation.
Topics: Animals; Cerebral Cortex; Denervation; Histamine; Hydrolysis; Hydroxydopamines; In Vitro Techniques; Injections, Intraventricular; Inositol Phosphates; Kinetics; Male; Norepinephrine; Oxidopamine; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sugar Phosphates; Yohimbine | 1985 |
Cardiac and coronary effects of prazosin and phenoxybenzamine during coronary hypotension.
Topics: Animals; Coronary Circulation; Dogs; Female; Heart; Hypotension; Male; Oxygen Consumption; Phenoxybenzamine; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Vasoconstriction | 1986 |
Characterization of alpha-adrenoceptors in myometrium of preparturient rats.
Topics: Animals; Binding, Competitive; Dihydroergotoxine; Female; In Vitro Techniques; Kinetics; Membranes; Myometrium; Phenoxybenzamine; Prazosin; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1985 |
Central adrenergic receptor control of renal function in conscious hypertensive rats.
Topics: Animals; Blood Pressure; Clonidine; Guanabenz; Hypertension; Kidney; Male; Natriuresis; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred SHR; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Urodynamics; Yohimbine | 1986 |
Norepinephrine-induced alteration in the coupling of alpha 1-adrenergic receptor occupancy to calcium efflux in rabbit aortic smooth muscle cells.
Topics: Animals; Aorta; Calcium; Cells, Cultured; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Prazosin; Rabbits; Receptors, Adrenergic, alpha | 1986 |
Modulation of positive inotropy and metabolic coronary dilatation by myocardial alpha-adrenoceptors.
Topics: Animals; Calcium Chloride; Catecholamines; Coronary Vessels; Dobutamine; Electric Stimulation; Glucagon; In Vitro Techniques; Isoproterenol; Male; Methoxamine; Muscle, Smooth, Vascular; Myocardial Contraction; Norepinephrine; Phenoxybenzamine; Phentolamine; Phenylephrine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tyramine; Vasodilation | 1985 |
Pre- and postjunctional alpha-adrenoceptors at sympathetic neuroeffector junction in bovine mesenteric lymphatics.
Topics: Adrenergic Fibers; Animals; Cattle; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Lymphatic System; Mesentery; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Synaptic Transmission; Time Factors; Tritium | 1986 |
Affinity labeling of the DDT1 MF-2 cell alpha 1-adrenergic receptor with [3H]phenoxybenzamine.
Topics: Affinity Labels; Animals; Azides; Cells, Cultured; Cricetinae; Epinephrine; Male; Mesocricetus; Molecular Weight; Phenoxybenzamine; Prazosin; Receptors, Adrenergic, alpha; Stereoisomerism; Tritium; Vas Deferens | 1986 |
Conformationally defined adrenergic agents. 3. Modifications to the carbocyclic ring of 5,6-dihydroxy-1-(2-imidazolinyl)tetralin: improved separation of alpha 1 and alpha 2 adrenergic activities.
Topics: Animals; Aorta; Dogs; Dose-Response Relationship, Drug; Female; Molecular Conformation; Norepinephrine; Phenoxybenzamine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Sympathomimetics | 1986 |
Receptor protection experiments confirm the identity of presynaptic alpha 2-autoreceptors.
Topics: Animals; Cerebral Cortex; Clonidine; Cyclazocine; Ethylketocyclazocine; Female; In Vitro Techniques; Male; Norepinephrine; Phenoxybenzamine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Synapses; Yohimbine | 1986 |
A difference in alpha-adrenoceptor mechanisms in vasa deferentia isolated from young and old rats.
Topics: Aging; Animals; In Vitro Techniques; Male; Norepinephrine; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens | 1986 |
Role of cyclic GMP in the modulation by endothelium of the adrenolytic action of prazosin in the rat isolated aorta.
Topics: Animals; Aorta, Thoracic; Cyclic GMP; Endothelium; In Vitro Techniques; Male; Methylene Blue; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1986 |
Evidence for the involvement of alpha-2 adrenoceptors in the sedation but not REM sleep inhibition by clonidine in the rat.
Topics: Animals; Clonidine; Electroencephalography; Hypnotics and Sedatives; Male; Phenoxybenzamine; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sleep, REM; Yohimbine | 1986 |
Antagonist effects of the enantiomers of 3-PPP towards alpha 1-adrenoceptors coupled to inositol phospholipid breakdown in the rat cerebral cortex.
Topics: Animals; Antiparkinson Agents; Atropine; Carbachol; Cerebral Cortex; Haloperidol; In Vitro Techniques; Inositol Phosphates; Male; Norepinephrine; Phenoxybenzamine; Piperidines; Prazosin; Raclopride; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Salicylamides; Stereoisomerism; Sugar Phosphates | 1987 |
Metabolism of adrenergic receptors and adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Cell Line; Contact Inhibition; Cyclic AMP; Dihydroalprenolol; Glioma; Half-Life; Membrane Proteins; Muscles; Phenoxybenzamine; Pindolol; Prazosin; Receptors, Adrenergic | 1987 |
Comparative effects of 6-hydroxydopamine and alpha-adrenoceptor antagonists on intrauterine migration and spacing of blastocysts in the rat.
Topics: Animals; Blastocyst; Embryo Implantation; Female; Hydroxydopamines; Myometrium; Norepinephrine; Oxidopamine; Phenoxybenzamine; Prazosin; Pregnancy; Rats; Rats, Inbred Strains; Sympathectomy, Chemical | 1987 |
Advances in the diagnosis and treatment of pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; Female; Humans; Male; Middle Aged; Phenoxybenzamine; Pheochromocytoma; Prazosin; Preoperative Care; Ultrasonography | 1988 |
Modulation of p,p'-DDT-induced tremor by catecholaminergic agents.
Topics: Animals; Apomorphine; Clonidine; DDT; Dopamine; Haloperidol; Male; Norepinephrine; Phenoxybenzamine; Prazosin; Propranolol; Rats; Rats, Inbred F344; Tremor; Yohimbine | 1987 |
An experimental approach to the choice of antiarrhythmic therapy.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cats; Coronary Disease; Diltiazem; Lidocaine; Mexiletine; Nifedipine; Phenoxybenzamine; Prazosin; Propafenone; Propiophenones; Propranolol; Stellate Ganglion; Verapamil | 1986 |
Inhibitory effects of formaldehyde inhalation on the cardiovascular and respiratory systems in unanesthetized rabbits.
Topics: Animals; Atropine; Formaldehyde; Guanethidine; Heart Rate; Hemodynamics; Lidocaine; Male; Parasympatholytics; Phenoxybenzamine; Prazosin; Rabbits; Respiration; Sympatholytics | 1986 |
Acetazolamide teratogenesis in Wistar rats: potentiation and antagonism by adrenergic agents.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Animals; Female; Limb Deformities, Congenital; Phenoxybenzamine; Phenylephrine; Prazosin; Pregnancy; Rats; Rats, Inbred Strains; Regional Blood Flow; Sympathomimetics; Uterus | 1986 |
Prazosin selectively antagonizes norepinephrine contractions at low-affinity, non-alpha adrenoceptor sites (extraceptors) in arterial muscle.
Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Prazosin; Rabbits | 1986 |
Monitoring the 24-hour urinary frequency in spontaneously hypertensive, and in Wistar rats: effect of alpha-blockers.
Topics: Animals; Hypertension; Male; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Urination | 1986 |
Antagonism by dopamine, but not noradrenaline receptor blockers of the anti-immobility activity of desipramine after different treatment schedules in the rat.
Topics: Animals; Desipramine; Dopamine; Male; Motor Activity; Norepinephrine; Phenoxybenzamine; Prazosin; Rats; Receptors, Adrenergic | 1986 |
Alpha-1 adrenoceptor selectivity of phenoxybenzamine in the rat kidney.
Topics: Animals; Binding, Competitive; Blood Pressure; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Kidney; Male; Natriuresis; Norepinephrine; Phenoxybenzamine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasopressins; Yohimbine | 1984 |
Impaired recovery of alpha 1- and alpha 2-adrenergic receptors in brain tissue of aged rats.
Topics: Aging; Animals; Brain; Brain Chemistry; Cerebral Cortex; Hypothalamus; Male; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha | 1984 |
Possible relationship between receptor reserve and the differential antagonism of alpha-1 and alpha-2 adrenoceptor-mediated pressor responses by calcium channel antagonists in the pithed rat.
Topics: Animals; Aorta, Thoracic; Azepines; Blood Pressure; Decerebrate State; Diltiazem; Dose-Response Relationship, Drug; Imidazoles; Male; Muscle Contraction; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Characterization of postjunctional alpha-1 and alpha-2 adrenoceptors activated by exogenous or nerve-released norepinephrine in the canine saphenous vein.
Topics: Animals; Clonidine; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; Imidazoles; Male; Methoxamine; Norepinephrine; Phenoxybenzamine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Saphenous Vein; Sympathetic Nervous System; Tyramine; Yohimbine | 1984 |
The relationship between alpha 1-adrenergic receptor occupation and the mobilization of intracellular calcium.
Topics: Animals; Binding, Competitive; Calcium; Cell Line; Cell Membrane; Kinetics; Mice; Mice, Inbred C3H; Muscles; Phenoxybenzamine; Phentolamine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha | 1984 |
The relationship between phosphatidylinositol metabolism and mobilization of intracellular calcium elicited by alpha1-adrenergic receptor stimulation in BC3H-1 muscle cells.
Topics: Animals; Calcium; Cell Line; Inositol; Kinetics; Mice; Mice, Inbred C3H; Muscles; Phenoxybenzamine; Phosphatidylinositols; Prazosin; Receptors, Adrenergic, alpha | 1984 |
Effects of alpha agonists and alpha blocking drugs on mouse plasma renin activity.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dose-Response Relationship, Drug; Drug Interactions; Heart Rate; Indoramin; Isoproterenol; Male; Mecamylamine; Methoxamine; Mice; Phenoxybenzamine; Prazosin; Renin | 1980 |
Pre- and postsynaptic alpha-adrenoceptor antagonists: differentiated cardiovascular effects in the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Heart Rate; Injections, Intravenous; Injections, Intraventricular; Male; Pentobarbital; Phenoxybenzamine; Phentolamine; Prazosin; Premedication; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1980 |
Differential influences of several alpha-adrenoceptor antagonists on alpha-adrenoceptor-mediated inotropic responses in the left atria of guinea-pigs.
Topics: Adrenergic alpha-Antagonists; Animals; Guinea Pigs; In Vitro Techniques; Myocardial Contraction; Phenoxybenzamine; Phentolamine; Phenylephrine; Prazosin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1982 |
Peripheral alpha 1- and alpha 2-adrenoreceptor mechanisms in blood pressure control.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Blood Pressure; Clonidine; Dioxins; Guanabenz; Idazoxan; Male; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Phentolamine; Prazosin; Pressoreceptors; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Synapses; Vascular Resistance | 1983 |
Urinary incontinence secondary to drugs.
Topics: Antihypertensive Agents; Antipsychotic Agents; Humans; Methyldopa; Phenoxybenzamine; Phentolamine; Prazosin; Reserpine; Urinary Bladder, Neurogenic; Urinary Incontinence | 1983 |
Adrenergic receptors in the urethra and prostate of the horse.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Drug Interactions; Horses; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenoxybenzamine; Phenylephrine; Prazosin; Prostate; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Urethra; Yohimbine | 1984 |
Pharmacological evidence for a functional role of the prejunctional alpha-adrenoreceptor in noradrenergic neurotransmission in the conscious rat.
Topics: Animals; Blood Pressure; Handling, Psychological; Heart Rate; Hydralazine; In Vitro Techniques; Male; Norepinephrine; Phenoxybenzamine; Phentolamine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Synaptic Transmission; Yohimbine | 1980 |
Prazosin protects vascular alpha-adrenoceptors against irreversible blockade by phenoxybenzamine.
Topics: Animals; Muscle Contraction; Muscle, Smooth; Phenoxybenzamine; Phentolamine; Potassium Chloride; Prazosin; Quinazolines; Rabbits; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1980 |
Aspects of the pharmacology of prazosin.
Topics: Animals; Cats; Clonidine; Femoral Artery; Femoral Vein; In Vitro Techniques; Mesenteric Arteries; Norepinephrine; Phenoxybenzamine; Phentolamine; Prazosin; Pulmonary Artery; Quinazolines; Rabbits; Receptors, Adrenergic, alpha; Vasodilation; Yohimbine | 1980 |
Alpha 2-adrenoceptors modulating insulin release from isolated pancreatic islets.
Topics: Animals; Dihydroergotamine; Epinephrine; In Vitro Techniques; Insulin; Islets of Langerhans; Male; Phenoxybenzamine; Phentolamine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1980 |
Complete blockade by phenoxybenzamine of alpha 1- but not of alpha 2-vascular receptors in dogs and the effects of propranolol.
Topics: Animals; Blood Pressure; Dogs; Epinephrine; Female; Male; Phenoxybenzamine; Phenylephrine; Prazosin; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1980 |
Inhibition of renin secretion by intrarenal alpha-adrenoceptor blockade.
Topics: Animals; Dogs; Kidney; Kinetics; Male; Phenoxybenzamine; Prazosin; Propranolol; Quinazolines; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Renin | 1981 |
Two distinct alpha1-adrenergic receptor sites in rat liver: differential binding of (--)-[3H]dihydroergocryptine. Effects of guanine nucleotides and proteolysis; implications for a two-site model of alpha-receptor regulation.
Topics: Animals; Binding Sites; Chymotrypsin; Dihydroergotoxine; Female; Guanine Nucleotides; In Vitro Techniques; Liver; Models, Chemical; Norepinephrine; Phenoxybenzamine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1981 |
Smooth muscle of rabbit aorta contains alpha 1-but not alpha 2-adrenoceptors.
Topics: Animals; Aorta; Drug Interactions; Female; Male; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Prazosin; Propranolol; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1981 |
Characteristics and metabolism of alpha 1 adrenergic receptors in a nonfusing muscle cell line.
Topics: Animals; Binding, Competitive; Cell Fusion; Cell Line; Cycloheximide; Kinetics; Mice; Muscles; Phenoxybenzamine; Prazosin; Protein Biosynthesis; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1982 |
The effects of prazosin, phentolamine and phenoxybenzamine on inhibitory alpha-adrenoceptors in the guniea-pig isolated ileum.
Topics: Acetylcholine; Animals; Drug Interactions; Electric Stimulation; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenoxybenzamine; Phentolamine; Prazosin; Quinazolines; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1982 |
Measurement of alpha-adrenoceptor "turnover' using phenoxybenzamine.
Topics: Animals; Clonidine; Male; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1982 |
[3H]Dihydroergocryptine binding to alpha-adrenergic receptors of human platelets. A reassessment using the selective radioligands [3H]prazosin, [3H]yohimbine, and [3H]rauwolscine.
Topics: Binding, Competitive; Blood Platelets; Dihydroergotoxine; Humans; Imipramine; In Vitro Techniques; Phenoxybenzamine; Prazosin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Serotonin; Yohimbine | 1982 |
Selective affinity labeling and molecular characterization of hepatic alpha 1-adrenergic receptors with [3H]phenoxybenzamine.
Topics: Affinity Labels; Animals; Cell Membrane; Epinephrine; Liver; Male; Molecular Weight; Phenoxybenzamine; Phosphorylases; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1983 |
Turnover in vivo of alpha 1-adrenergic receptors in rat submaxillary glands.
Topics: Animals; Clonidine; Cycloheximide; Dihydroalprenolol; Male; Phenoxybenzamine; Prazosin; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Submandibular Gland | 1983 |
Simultaneous loss and reappearance of alpha 1-adrenergic responses and [3H]prazosin binding sites in rat liver after irreversible blockade by phenoxybenzamine.
Topics: Animals; Calcium; Female; Glucose; Kinetics; Liver; Phenoxybenzamine; Phenylephrine; Prazosin; Quinazolines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1983 |
Chronic treatment with imipramine: further functional evidence for the enhanced noradrenergic transmission in flexor reflex activity.
Topics: Animals; Desipramine; Hindlimb; Imipramine; Male; Norepinephrine; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reflex; Spinal Cord; Synaptic Transmission | 1983 |
An electrophysiological study of excitatory neuromuscular transmission in the guinea-pig main pulmonary artery.
Topics: Action Potentials; Animals; Female; Guanethidine; Guinea Pigs; Male; Membrane Potentials; Muscle, Smooth, Vascular; Neuromuscular Junction; Norepinephrine; Phenoxybenzamine; Phentolamine; Prazosin; Pulmonary Artery; Synaptic Transmission; Tetrodotoxin | 1983 |
Cardiovascular adrenoreceptor function during compensatory and decompensatory hemorrhagic shock.
Topics: Animals; Hemodynamics; Levulinic Acids; Male; Phenoxybenzamine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Shock, Hemorrhagic; Time Factors; Vasoconstriction; Vasodilation; Yohimbine | 1984 |
The recovery of alpha-adrenoceptor function and binding sites after phenoxybenzamine. An index of receptor turnover?
Topics: Animals; Blood Pressure; Guanabenz; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Norepinephrine; Phenoxybenzamine; Phenylephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha | 1984 |
Pharmacological differentiation of postsynaptic alpha adrenoceptors in the dog saphenous vein.
Topics: Animals; Azepines; Dogs; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Naphthols; Norepinephrine; Phenoxybenzamine; Prazosin; Receptors, Adrenergic, alpha; Saphenous Vein; Tetrahydronaphthalenes; Yohimbine | 1984 |
Distribution of alpha-adrenergic receptors in the rabbit nephron.
Topics: Animals; Atenolol; Female; Isoproterenol; Kidney Tubules, Collecting; Kidney Tubules, Proximal; Norepinephrine; Phenoxybenzamine; Prazosin; Quinazolines; Rabbits; Radioligand Assay; Receptors, Adrenergic, alpha; Tissue Distribution | 1984 |
Identification of the subunit-binding site of alpha 2-adrenergic receptors using [3H]phenoxybenzamine.
Topics: Binding, Competitive; Blood Platelets; Chromatography, Affinity; Epinephrine; Humans; Kinetics; Molecular Weight; Phenoxybenzamine; Phentolamine; Prazosin; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Interactions of epinephrine, norepinephrine, dopamine and their corresponding alpha-methyl-substituted derivatives with alpha and beta adrenoceptors in the pithed rat.
Topics: Animals; Blood Pressure; Decerebrate State; Deoxyepinephrine; Dopamine; Dose-Response Relationship, Drug; Epinephrine; Male; Nordefrin; Norepinephrine; Phenoxybenzamine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Reserpine; Yohimbine | 1984 |
Glucagon and glucose as major regulators of glycogen metabolism in primary cultured rat hepatocytes.
Topics: Animals; Cells, Cultured; Glucagon; Glucose; Glycogen Synthase; Insulin; Kinetics; Liver; Liver Glycogen; Male; Phenoxybenzamine; Phenylephrine; Phosphorylases; Prazosin; Rats; Rats, Inbred Strains | 1984 |
Vasopressin and urine flow rate responses to stress in conscious dogs.
Topics: Animals; Avoidance Learning; Blood Pressure; Conditioning, Operant; Diuresis; Dogs; Heart Rate; Hematocrit; Kidney Function Tests; Male; Osmolar Concentration; Phenoxybenzamine; Prazosin; Stress, Physiological; Urination; Vasopressins | 1984 |
Alpha 1-noradrenergic regulation of hypothalamic progestin receptors and guinea pig lordosis behavior.
Topics: Animals; Brain Mapping; Clonidine; Estradiol; Female; Guinea Pigs; Hypothalamus; Norepinephrine; Phenoxybenzamine; Posture; Prazosin; Receptors, Progesterone; Sexual Behavior, Animal | 1984 |
The effect of adrenergic stimulation on urinary prostaglandin E2 and 6 keto PGF1 alpha in man.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Dinoprostone; Humans; Isoproterenol; Middle Aged; Norepinephrine; Phenoxybenzamine; Phentolamine; Prazosin; Prohibitins; Prostaglandins E; Radioimmunoassay; Receptors, Adrenergic | 1983 |
Cerebral blood flow in hypertension.
Topics: Antihypertensive Agents; Brain Ischemia; Cerebrovascular Circulation; Cerebrovascular Disorders; Diazoxide; Dihydralazine; Emergencies; Homeostasis; Humans; Hypertension; Nitroprusside; Phenoxybenzamine; Prazosin; Risk; Trimethaphan | 1983 |
Hypertensive crisis in prazosin-treated pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Catecholamines; Female; Humans; Hypertension; Middle Aged; Phenoxybenzamine; Pheochromocytoma; Prazosin; Premedication; Quinazolines | 1984 |
Serotonin stimulates rapid increase of inositol 1,4,5-trisphosphate in ovine uterine artery: correlation with contractile state.
Topics: Adrenergic alpha-Antagonists; Animals; Arteries; Calcium; Female; Inositol 1,4,5-Trisphosphate; Ketanserin; Phenoxybenzamine; Prazosin; Pregnancy; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Sheep; Time Factors; Uterine Contraction; Uterus | 1995 |
Differential inhibition in the human vas deferens by phenoxybenzamine: a possible mechanism for its contraceptive action.
Topics: Adrenergic alpha-Antagonists; Calcium; Clonidine; Contraceptive Agents, Male; Cystamine; Humans; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Phenoxybenzamine; Prazosin; Vas Deferens | 1995 |
Medical management of benign prostatic hyperplasia: a canine model comparing the in vivo efficacy of alpha-1 adrenergic antagonists in the prostate.
Topics: Adrenergic alpha-Antagonists; Animals; Dogs; Dose-Response Relationship, Drug; Epinephrine; Male; Muscle Contraction; Phenoxybenzamine; Prazosin; Prostate; Prostatic Hyperplasia; Receptors, Adrenergic, alpha; Sulfonamides; Tamsulosin | 1993 |
Pharmacological characterization of noradrenaline-induced contractions of the porcine isolated palmar lateral vein and palmar common digital artery.
Topics: Adrenergic alpha-Antagonists; Animals; Arteries; Berberine; Drug Interactions; Drug Synergism; Forelimb; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Prazosin; Receptors, Adrenergic, alpha; Reproducibility of Results; Sulfonamides; Swine; Veins; Yohimbine | 1995 |
Functional bladder neck obstruction: a rare cause of renal failure.
Topics: Adult; Catheters, Indwelling; Creatinine; Electromyography; Female; Follow-Up Studies; Humans; Kidney Failure, Chronic; Male; Middle Aged; Phenoxybenzamine; Prazosin; Pressure; Self Care; Urinary Bladder; Urinary Bladder Neck Obstruction; Urinary Catheterization; Urinary Retention; Urodynamics; Video Recording | 1995 |
Selective enrichment with alpha 1A- and alpha 1B-adrenoceptor subtypes in rat brain cortical membranes.
Topics: Adrenergic alpha-Antagonists; Alkylating Agents; Alkylation; Animals; Binding Sites; Cerebral Cortex; Clonidine; Cystamine; Dihydropyridines; Dioxanes; Phenoxybenzamine; Phentolamine; Prazosin; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha | 1994 |
The interaction between enalaprilat and selected alpha-adrenoceptor antagonists in isolated rat tail arteries.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Arteries; Computer Simulation; Drug Interactions; Drug Synergism; Enalaprilat; Muscle, Smooth, Vascular; Phenoxybenzamine; Phentolamine; Phenylephrine; Prazosin; Rats; Tail; Yohimbine | 1994 |
Evidence for multiple adrenoceptor sites in rainbow trout vasculature.
Topics: Animals; Blood Pressure; Epinephrine; Hexamethonium Compounds; Oncorhynchus mykiss; Phenoxybenzamine; Phentolamine; Prazosin; Receptors, Adrenergic; Sympathectomy, Chemical | 1993 |
Alpha 1b-adrenoceptor-mediated stimulation of Na-K pump current in adult rat ventricular myocytes.
Topics: Adrenergic alpha-Antagonists; Animals; Cells, Cultured; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Heart; Heart Ventricles; Male; Myocardium; Ouabain; Phenoxybenzamine; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Sodium-Potassium-Exchanging ATPase; Ventricular Function, Left | 1993 |
Pharmacological characterization of two distinct alpha 1-adrenoceptor subtypes in rabbit thoracic aorta.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Clonidine; In Vitro Techniques; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Prazosin; Rabbits; Receptors, Adrenergic, alpha | 1993 |
The effects of tyramine on salivary flow rate and protein secretion by rat submandibular glands.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Isoelectric Focusing; Male; Metoprolol; Phenoxybenzamine; Prazosin; Propanolamines; Propranolol; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Saliva; Salivary Proteins and Peptides; Salivation; Secretory Rate; Serine Endopeptidases; Stimulation, Chemical; Submandibular Gland; Tyramine; Yohimbine | 1993 |
In vivo recovery of alpha 1-adrenoceptors in rat myocardial tissue after alkylation with phenoxybenzamine.
Topics: Alkylation; Animals; Binding Sites; Heart; Hydrolysis; Inositol Phosphates; Male; Myocardium; Norepinephrine; Phenoxybenzamine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha | 1994 |
Age-related alterations in receptor density and metabolic activity in the brain.
Topics: Aging; Animals; Brain; Choline O-Acetyltransferase; Down-Regulation; Glycolysis; Male; Oxygen Consumption; Phenoxybenzamine; Potassium; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic | 1993 |
Adrenoceptor subtypes involved in neurally evoked sympathetic vasoconstriction in the anterior choroid of cats.
Topics: Animals; Cats; Choroid; Dose-Response Relationship, Drug; Electric Stimulation; Laser-Doppler Flowmetry; Nictitating Membrane; Phenoxybenzamine; Phentolamine; Prazosin; Receptors, Adrenergic, alpha-1; Sympathetic Nervous System; Time Factors; Vasoconstriction | 1993 |
Inhibitory influence of sympathetic nerves on afferent nerve-induced extravasation in the rat incisor pulp upon direct electrical stimulation of the tooth.
Topics: Animals; Capillary Permeability; Dental Pulp; Dioxanes; Electric Stimulation; Evans Blue; Idazoxan; Laser-Doppler Flowmetry; Male; Neurons, Afferent; Phenoxybenzamine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Sympathectomy; Sympathetic Nervous System; Vasomotor System | 1993 |
Investigation of the actions of chloroethylclonidine in rat aorta.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Aorta; Clonidine; Cystamine; Dioxanes; Dose-Response Relationship, Drug; Drug Synergism; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxathiins; Phenoxybenzamine; Phentolamine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Spiperone; Xylazine; Yohimbine | 1995 |
Alpha adrenergic neurons inhibit luteinizing hormone pulse amplitude in breeding season ewes.
Topics: Adrenergic alpha-Antagonists; Animals; Drug Implants; Estradiol; Feedback; Female; Luteinizing Hormone; Neurons; Ovariectomy; Phenoxybenzamine; Prazosin; Preoptic Area; Receptors, Adrenergic, alpha; Reproduction; Seasons; Sheep; Yohimbine | 1996 |
Rilmenidine activates postjunctional alpha 1- and alpha 2-adrenoceptors in the canine saphenous vein.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium Channel Blockers; Clonidine; Dihydropyridines; Dogs; Female; Idazoxan; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Isotope Labeling; Male; Medetomidine; Muscle Contraction; Muscle, Smooth; Osmolar Concentration; Oxazoles; Phenoxybenzamine; Prazosin; Protein Binding; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine; Saphenous Vein; Tritium; Yohimbine | 1996 |
Endothelial modulation of alpha 1-adrenoceptor contractile responses in the tail artery of spontaneously hypertensive rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; In Vitro Techniques; Male; Phenoxybenzamine; Phenylephrine; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha-1; Tail | 1996 |
Sustained increase in rat myocardial alpha 1A-adrenoceptors induced by 6-hydroxydopamine treatment involves a decelerated receptor turnover.
Topics: Adrenergic Agents; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Body Weight; Dioxanes; Male; Myocardium; Norepinephrine; Organ Size; Oxidopamine; Phenoxybenzamine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Up-Regulation | 1996 |
Mechanism of resistance to alpha-adrenergic receptor antagonists of renal nerve stimulation-induced vasoconstriction at low frequencies.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic Antagonists; Animals; Electric Stimulation; In Vitro Techniques; Kidney; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Prazosin; Rats; Rats, Sprague-Dawley; Renal Artery; Tritium; Vasoconstriction; Vasoconstrictor Agents; Yohimbine | 1997 |
Metyrosine and pheochromocytoma.
Topics: Adolescent; Adrenal Gland Neoplasms; Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; alpha-Methyltyrosine; Catecholamines; Child; Drug Therapy, Combination; Enzyme Inhibitors; Female; Heart Rate; Humans; Hypertension; Intraoperative Complications; Male; Methyltyrosines; Middle Aged; Phenoxybenzamine; Pheochromocytoma; Prazosin; Retrospective Studies; Treatment Outcome | 1997 |
The preoperative management of phaeochromocytoma.
Topics: Adolescent; Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Adult; Blood Pressure; Female; Humans; Labetalol; Male; Middle Aged; Phenoxybenzamine; Pheochromocytoma; Prazosin; Preoperative Care; Retrospective Studies | 1998 |
Dopaminergic control of angiotensin II-induced vasopressin secretion in vitro.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Angiotensin II; Animals; Apomorphine; Arginine Vasopressin; Benzazepines; Domperidone; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Hypothalamo-Hypophyseal System; Kinetics; Male; Models, Neurological; Organ Culture Techniques; Phenoxybenzamine; Prazosin; Rats; Rats, Long-Evans; Receptors, Dopamine D1; Receptors, Dopamine D2; Time Factors | 1998 |
Insights into the unusual alpha adrenoceptor subtype in dog saphenous vein using phenoxybenzamine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkylating Agents; Alkylation; Animals; Azepines; Binding, Competitive; Brimonidine Tartrate; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Phenoxybenzamine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-2; Saphenous Vein; Yohimbine | 1999 |
Functional characterization of alpha1-adrenoceptor subtypes in longitudinal and circular muscle of human vas deferens.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Alkylating Agents; Binding, Competitive; Clonidine; Dose-Response Relationship, Drug; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenoxybenzamine; Piperazines; Prazosin; Receptors, Adrenergic; Spiperone; Vas Deferens | 1999 |
Non-specific action of methoxamine on Ito, and the cloned channels hKv 1.5 and Kv 4.2.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cell Line; Cloning, Molecular; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Ethylmaleimide; Heart Ventricles; Humans; Kv1.5 Potassium Channel; Male; Membrane Potentials; Methoxamine; Myocardium; Phenoxybenzamine; Phenylephrine; Potassium Channels; Potassium Channels, Voltage-Gated; Prazosin; Rats; Receptors, Adrenergic, alpha; Recombinant Fusion Proteins; Shal Potassium Channels; Ventricular Function | 1999 |
Expression and pharmacological characterization of alpha1-adrenoceptors in rat seminal vesicle.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium Channel Blockers; Clonidine; Dioxanes; Epinephrine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenoxybenzamine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seminal Vesicles | 1999 |
Management of functional bladder neck obstruction in women: use of alpha-blockers and pediatric resectoscope for bladder neck incision.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Combined Modality Therapy; Equipment Design; Female; Humans; Middle Aged; Phenoxybenzamine; Prazosin; Proctoscopes; Retrospective Studies; Urinary Bladder Neck Obstruction | 1999 |
Regulation of renal artery smooth muscle tone by alpha1-adrenoceptors: role of voltage-gated calcium channels and intracellular calcium stores.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Diltiazem; Dioxanes; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Ischemia; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Phenoxybenzamine; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Renal Artery; Renal Circulation; Swine; Thapsigargin; Verapamil | 2000 |
Sympathetic control of nasal blood flow in the rat mediated by alpha(1)-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Adrenergic Fibers; Animals; Electric Stimulation; Ganglia, Sympathetic; Laser-Doppler Flowmetry; Male; Nasal Cavity; Nasal Mucosa; Norepinephrine; Phenoxybenzamine; Phentolamine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Vasoconstriction; Yohimbine | 2001 |
Effects of noradrenaline on cytosolic concentrations of Ca(2+) in cultured corpus cavernosum smooth muscle cells of the rabbit.
Topics: Actins; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Calcium; Calcium Signaling; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Penile Erection; Penis; Phenoxybenzamine; Prazosin; Propranolol; Rabbits; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Sympathetic Fibers, Postganglionic | 2002 |
Adrenergic mechanisms in antinociceptive effects of non steroidal anti-inflammatory drugs in acute thermal nociception in mice.
Topics: Adrenergic alpha-Antagonists; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Hot Temperature; Mice; Nociceptors; Pain Measurement; Phenoxybenzamine; Prazosin; Reaction Time; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Yohimbine | 2002 |
Urethral pressure profile and hemodynamic effects of phenoxybenzamine and prazosin in non-sedated male beagle dogs.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Dog Diseases; Dogs; Heart Rate; Injections, Intravenous; Kinetics; Male; Phenoxybenzamine; Prazosin; Pressure; Random Allocation; Treatment Outcome; Urethra; Urethral Obstruction; Urodynamics | 2003 |
Contractile actions of imidazoline alpha-adrenoceptor agonists and effects of noncompetitive alpha1-adrenoceptor antagonists in human vas deferens.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Dibenzylchlorethamine; Dose-Response Relationship, Drug; Humans; Imidazoles; Male; Muscle Contraction; Norepinephrine; Oxymetazoline; Phenoxybenzamine; Prazosin; Receptors, Adrenergic, alpha-1; Tetrahydronaphthalenes; Vas Deferens | 2003 |
Functional characterization of alpha-adrenoceptors mediating pupillary dilation in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic Fibers; Animals; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Injections, Intravenous; Male; Mydriasis; Norepinephrine; Phenoxybenzamine; Phentolamine; Piperazines; Prazosin; Pupil; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Yohimbine | 2003 |
Studies of alpha-adrenoceptor antagonists on sympathetic mydriasis in rabbits.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Isoquinolines; Male; Mydriasis; Mydriatics; Naphthyridines; Phenoxybenzamine; Phentolamine; Piperazines; Prazosin; Pupil; Rabbits; Sympathetic Nervous System | 2003 |
[The growth inhibition effect of alpha-adrenoceptor antagonists on androgen- independent prostate cancer cell line].
Topics: Adrenergic alpha-Antagonists; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Humans; Male; Phenoxybenzamine; Prazosin; Prostatic Neoplasms; Quinazolines | 2004 |
Receptors involved in moxonidine-stimulated atrial natriuretic peptide release from isolated normotensive rat hearts.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Bridged Bicyclo Compounds; Brimonidine Tartrate; Clonidine; Coronary Circulation; Drug Synergism; Female; Heart; Heart Rate; Heptanes; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Myocardium; Perfusion; Phenoxybenzamine; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine | 2006 |
Neurotransmitter-mediated action of an antagonist of growth hormone-releasing hormone on anxiolysis in mice.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Bicuculline; Cyproheptadine; Disease Models, Animal; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Maze Learning; Methysergide; Mice; Neurotransmitter Agents; Phenoxybenzamine; Prazosin; Sermorelin; Swimming | 2012 |
Neuropeptide AF induces anxiety-like and antidepressant-like behavior in mice.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Anxiety; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Immobility Response, Tonic; Male; Maze Learning; Mice; Oligopeptides; Phenoxybenzamine; Prazosin; Serotonin Agents; Swimming | 2014 |