phenoxybenzamine and phenobarbital

phenoxybenzamine has been researched along with phenobarbital in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199013 (68.42)18.7374
1990's1 (5.26)18.2507
2000's1 (5.26)29.6817
2010's4 (21.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Daniell, HB; Ducker, TB; Salcman, M1
Tabrizchi, R; Triggle, CR1
King, AB; Thomas, JA1
Kaniike, K; Kurogochi, Y1
Hupka, AL; Karler, R; Williams, JK1
Aston, R; Roberts, VL2
Bainbridge, JG; Greenwood, DT1
Leonard, BE1
Evces, CR; McElhaney, JH1
Andén, NE; Dahlström, A; Fuxe, K; Larsson, K1
Borne, RF; Davis, WM1
MOORE, KE1

Reviews

1 review(s) available for phenoxybenzamine and phenobarbital

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

18 other study(ies) available for phenoxybenzamine and phenobarbital

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Experimental spinal cord trauma, III: Therapeutic effect of immobilization and pharmacologic agents.
    Surgical neurology, 1978, Volume: 10, Issue:1

    Topics: Animals; Dextrans; Haplorhini; Immobilization; Methyldopa; Phenobarbital; Phenoxybenzamine; Spinal Cord Injuries; Vasoconstrictor Agents

1978
A comparison of the effects of acute versus chronic administration of phenoxybenzamine on pressor responses elicited by the selective alpha 1-adrenoceptor agonist cirazoline in the pithed rat preparation.
    Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:6

    Topics: Adaptation, Physiological; Adrenergic alpha-Agonists; Anesthesia; Animals; Blood Pressure; Calcium; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Imidazoles; Male; Nifedipine; Phenobarbital; Phenoxybenzamine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Time Factors

1992
Effect of exogenous dopamine on rat adrenal ascorbic acid.
    The Journal of pharmacology and experimental therapeutics, 1968, Volume: 159, Issue:1

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Ascorbic Acid; Dopamine; Epinephrine; Male; Morphine; Phenobarbital; Phenoxybenzamine; Rats; Stimulation, Chemical

1968
[Effect of psychotropic drugs on the K + -dependent phosphatase activity in guinea pig brain microsomes].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1972, Volume: 68, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Chlordiazepoxide; Chlorpromazine; Desipramine; Diazepam; Guinea Pigs; Histamine; Hydroxyzine; Imipramine; Meprobamate; Microsomes; Morphine; Nialamide; Phenelzine; Phenobarbital; Phenoxybenzamine; Phosphoric Monoester Hydrolases; Pilocarpine; Potassium; Procaine; Reserpine; Tranquilizing Agents

1972
Effects of convulsant barbiturates on vascular smooth muscle.
    The Journal of pharmacy and pharmacology, 1969, Volume: 21, Issue:12

    Topics: Acetylcholine; Animals; Aorta; Atropine; Barbiturates; Histamine; In Vitro Techniques; Muscle, Smooth; Norepinephrine; Pentobarbital; Phenobarbital; Phenoxybenzamine; Rabbits; Stereoisomerism; Tachyphylaxis

1969
Quantitative aspects of vibration-induced mortality.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 182, Issue:2

    Topics: Amphetamine; Animals; Atropine; Chlordiazepoxide; Dextroamphetamine; Epinephrine; Hexamethonium Compounds; Isoproterenol; Lidocaine; Male; Mice; Motion Sickness; Neostigmine; Phenobarbital; Phenoxybenzamine; Phenylephrine; Piperazines; Statistics as Topic; Sympathomimetics; Time Factors; Vibration

1969
Tranquillizing effects of propranolol demonstrated in rats.
    Neuropharmacology, 1971, Volume: 10, Issue:4

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Animals; Anxiety; Atropine; Central Nervous System; Chlordiazepoxide; Chlorpromazine; Conditioning, Psychological; Depression, Chemical; Electroshock; Haloperidol; Hexamethonium Compounds; Humans; Isomerases; Male; Phenobarbital; Phenoxybenzamine; Propranolol; Rats; Rats, Inbred Strains; Stereotaxic Techniques; Time Factors

1971
The effect of some beta-adrenergic blocking and other drugs on brain lactate levels following electroshock.
    Neuropharmacology, 1971, Volume: 10, Issue:4

    Topics: Acetanilides; Allyl Compounds; Amino Alcohols; Animals; Brain; Brain Chemistry; Chlordiazepoxide; Electroshock; Female; Indoles; Lactates; Male; Mice; Mice, Inbred Strains; Nitrobenzenes; Phenethylamines; Phenobarbital; Phenoxybenzamine; Propranolol; Sulfonamides; Sympatholytics; Time Factors

1971
Some effects of drugs on the low frequency whole body vibration response of dogs.
    Aerospace medicine, 1971, Volume: 42, Issue:4

    Topics: Animals; Dogs; Mathematics; Morphine; Phenobarbital; Phenoxybenzamine; Vibration

1971
Functional role of the nigro-neostriatal dopamine neurons.
    Acta pharmacologica et toxicologica, 1966, Volume: 24, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Basal Ganglia; Behavior, Animal; Caudate Nucleus; Chlorpromazine; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Haloperidol; Neurons; Nialamide; Norepinephrine; Phenobarbital; Phenoxybenzamine; Promethazine; Propranolol; Rats; Reserpine

1966
The effect of drugs on vibration tolerance.
    Archives internationales de pharmacodynamie et de therapie, 1965, Volume: 155, Issue:2

    Topics: Animals; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Hydroxyzine; In Vitro Techniques; Iproniazid; Lung; Mephenesin; Meprobamate; Mice; Morphine; Mortality; Pentobarbital; Phenobarbital; Phenoxybenzamine; Reserpine; Serotonin; Stress, Physiological; Vibration

1965
Pharmacologic investigation of compounds related to 3,4-methylenedioxyamphetamine (MDA).
    Substance and alcohol actions/misuse, 1984, Volume: 5, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Haloperidol; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Phenobarbital; Phenoxybenzamine; Propranolol

1984
THE ROLE OF ENDOGENOUS NOREPINEPHRINE IN THE TOXICITY OF D-AMPHETAMINE IN AGGREGATED MICE.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 144

    Topics: Atropine; Brain Chemistry; Bretylium Compounds; Chlorpromazine; Dextroamphetamine; Hydrazines; Iproniazid; Isoproterenol; Metabolism; Metaraminol; Mice; Myocardium; Norepinephrine; Pharmacology; Phenobarbital; Phenoxybenzamine; Research; Reserpine; Scopolamine; Toxicology

1964