phenoxybenzamine and metoprolol

phenoxybenzamine has been researched along with metoprolol in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199010 (43.48)18.7374
1990's3 (13.04)18.2507
2000's4 (17.39)29.6817
2010's6 (26.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Ahlman, H; Dahlström, A; Kewenter, J; Larsson, I; Lundberg, JM; Pettersson, G1
Chang, PI; Rutlen, DL1
de Moraes, S; Spadari, RC1
Gurll, NJ; Lechner, RB; Reynolds, DG1
Bloom, FE; Chouvet, GE; Siggins, GR; Staunton, DA; Svensson, TH1
Joles, JA; Nicaise, E; Sanders, M; Schot, A1
Ablad, B; Dahlöf, C; Ljung, B1
Ablad, B; Aurell, M; Kopp, U; Sjölander, M1
Ciccone, CD; Zambraski, EJ1
Huerta, FI; Sharma, AD; Waxman, MB1
Bradley, T; Hjemdahl, P; Kopp, U1
Abe, K; Hidaka, S; Okina, A; Tashiro, M1
Dugas, G; Fuller, J; Singh, S; Watson, J1
Amann, K; Câmpean, V; Gross, ML; Hofstetter, J; Koch, A; Ritz, E; Veelken, R1
Bowen, FW; Civan, J; Gleason, T; Orlin, A1
Akcay, F; Cadirci, E; Hacimuftuoglu, A; Halici, Z; Suleyman, H1
Kumar, A; Pahwa, HS; Rai, A; Srivastava, R1

Reviews

1 review(s) available for phenoxybenzamine and metoprolol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

22 other study(ies) available for phenoxybenzamine and metoprolol

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
The release of serotonin from rat duodenal enterochromaffin cells by adrenoceptor agonists studied in vitro.
    Acta physiologica Scandinavica, 1978, Volume: 103, Issue:2

    Topics: Acetylcholine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Chromaffin System; Dopamine; Duodenum; Enterochromaffin Cells; Epinephrine; Isoproterenol; Male; Metoprolol; Norepinephrine; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Serotonin

1978
Effects of beta-adrenergic agonists on splanchnic vascular volume and cardiac output.
    The American journal of physiology, 1991, Volume: 261, Issue:5 Pt 2

    Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Blood Volume; Cardiac Output; Denervation; Dogs; Female; Heart Rate; Isoproterenol; Male; Metoprolol; Muscle, Smooth, Vascular; Phenoxybenzamine; Pressoreceptors; Receptors, Adrenergic, beta; Splanchnic Circulation; Splenectomy; Terbutaline

1991
Subsensitivity to beta-adrenoceptor agonists in pacemakers isolated from senescent rats.
    General pharmacology, 1991, Volume: 22, Issue:5

    Topics: Adrenergic beta-Agonists; Aging; Animals; Cocaine; Ethanolamines; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Norepinephrine; Oxidopamine; Phenoxybenzamine; Rats; Rats, Inbred Strains

1991
Role of the autonomic nervous system in mediating the response to naloxone in canine hemorrhagic shock.
    Circulatory shock, 1985, Volume: 16, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Autonomic Nervous System; Blood Pressure; Dogs; Female; Heart Rate; Isoproterenol; Male; Mathematics; Metoprolol; Muscle Denervation; Naloxone; Phenoxybenzamine; Shock, Hemorrhagic; Stroke Volume

1985
Systemic phenoxybenzamine but not beta-adrenergic antagonists block noradrenergic inhibition of cerebellar Purkinje and hippocampal pyramidal neurons.
    Journal of neural transmission, 1988, Volume: 73, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Cerebellum; gamma-Aminobutyric Acid; Hippocampus; Male; Metoprolol; Neurons; Norepinephrine; Phenoxybenzamine; Propanolamines; Propranolol; Purkinje Cells; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reference Values

1988
Effects of NaHCO3, alpha-, and beta-adrenergic blockade on albuminuria after swimming in splenectomized dogs.
    International journal of sports medicine, 1984, Volume: 5, Issue:6

    Topics: Acidosis; Albuminuria; Animals; Bicarbonates; Blood; Dogs; Hydrogen-Ion Concentration; Metoprolol; Muramidase; Phenoxybenzamine; Renal Circulation; Renin; Sodium Bicarbonate; Splenectomy; Swimming

1984
Pre- and postjunctional beta-adrenoceptor mediated effects on transmitter release and effector response in the isolated rat portal vein.
    Acta physiologica Scandinavica, 1980, Volume: 108, Issue:1

    Topics: Animals; Autacoids; Electric Stimulation; Female; Hypertension; Isoproterenol; Male; Metoprolol; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Portal Vein; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tetrodotoxin; Vasoconstriction

1980
The role of prostaglandins in the alpha- and beta-adrenoceptor mediated renin release response to graded renal nerve stimulation.
    Pflugers Archiv : European journal of physiology, 1981, Volume: 391, Issue:1

    Topics: Animals; Diclofenac; Dogs; Drug Combinations; Female; Indomethacin; Kidney; Male; Metoprolol; Phenoxybenzamine; Prostaglandins; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Renin; Stimulation, Chemical

1981
Effects of phenoxybenzamine, metoprolol, captopril, and meclofenamate on cardiovascular function in deoxycorticosterone acetate hypertensive Yucatan miniature swine.
    Canadian journal of physiology and pharmacology, 1983, Volume: 61, Issue:2

    Topics: Animals; Blood Pressure; Captopril; Desoxycorticosterone; Female; Heart Rate; Hemodynamics; Hypertension; Male; Meclofenamic Acid; Metoprolol; ortho-Aminobenzoates; Phenoxybenzamine; Proline; Propanolamines; Swine; Swine, Miniature

1983
Effect of adrenergic stimulation and blockade on ventricular defibrillation in the rat.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:3

    Topics: Albuterol; Animals; Atropine; Isoproterenol; Male; Metoprolol; Norepinephrine; Phenoxybenzamine; Phenylephrine; Propranolol; Rats; Rats, Inbred Strains; Sympathomimetics; Time Factors; Ventricular Fibrillation

1983
Renal venous outflow and urinary excretion of norepinephrine, epinephrine, and dopamine during graded renal nerve stimulation.
    The American journal of physiology, 1983, Volume: 244, Issue:1

    Topics: Animals; Catecholamines; Denervation; Dogs; Dopamine; Electric Stimulation; Epinephrine; Female; Kidney; Male; Metoprolol; Norepinephrine; Phenoxybenzamine; Renal Artery; Renal Circulation; Renal Veins

1983
The effects of tyramine on salivary flow rate and protein secretion by rat submandibular glands.
    Journal of dental research, 1993, Volume: 72, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Isoelectric Focusing; Male; Metoprolol; Phenoxybenzamine; Prazosin; Propanolamines; Propranolol; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Saliva; Salivary Proteins and Peptides; Salivation; Secretory Rate; Serine Endopeptidases; Stimulation, Chemical; Submandibular Gland; Tyramine; Yohimbine

1993
Pheochromocytoma and pregnancy: a case report and review of anesthetic management.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2004, Volume: 51, Issue:2

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Anesthesia, General; Anesthesia, Obstetrical; Antihypertensive Agents; Cesarean Section; Female; Humans; Hypertension; Laparoscopy; Magnetic Resonance Imaging; Metoprolol; Monitoring, Intraoperative; Phenoxybenzamine; Pheochromocytoma; Pregnancy; Pregnancy Complications, Neoplastic

2004
Nonhypotensive dose of beta-adrenergic blocker ameliorates capillary deficits in the hearts of rats with moderate renal failure.
    Virchows Archiv : an international journal of pathology, 2006, Volume: 449, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Arterioles; Blood Pressure; Capillaries; Coronary Vessels; Endothelin-1; Kidney Failure, Chronic; Male; Metoprolol; Phenoxybenzamine; Rats; Rats, Sprague-Dawley

2006
Management of type A aortic dissection and a large pheochromocytoma: a surgical dilemma.
    The Annals of thoracic surgery, 2006, Volume: 81, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia, General; Aortic Aneurysm; Aortic Dissection; Aortography; Atrial Fibrillation; Cardiac Catheterization; Catecholamines; Catheter Ablation; Circulatory Arrest, Deep Hypothermia Induced; Combined Modality Therapy; Critical Care; Emergencies; Hematoma; Humans; Hypertension; Incidental Findings; Intraoperative Complications; Male; Metoprolol; Middle Aged; Phenoxybenzamine; Pheochromocytoma; Postoperative Complications; Retroperitoneal Neoplasms; Tomography, X-Ray Computed

2006
Indirect role of beta2-adrenergic receptors in the mechanism of analgesic action of nonsteroidal antiinflammatory drugs.
    Critical care medicine, 2010, Volume: 38, Issue:9

    Topics: Adrenalectomy; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Male; Metoprolol; Pain; Phenoxybenzamine; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta-2

2010
Unsuspected pheochromocytoma of the urinary bladder: reminder of an important clinical lesson.
    BMJ case reports, 2012, Aug-08, Volume: 2012

    Topics: Adult; Antihypertensive Agents; Cystectomy; Cystoscopy; Headache; Hematuria; Humans; Hypertension; Male; Metoprolol; Nitroprusside; Phenoxybenzamine; Phentolamine; Pheochromocytoma; Treatment Outcome; Urinary Bladder Neoplasms; Urination

2012