Compounds > phenoxybenzamine

phenoxybenzamine and digoxin

phenoxybenzamine has been researched along with digoxin in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19905 (45.45)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's5 (45.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Hanson, EC; Powell, WJ; Sagar, KB1
Wosornu, L1
Garan, H; Hamlin, NP; Powell, WJ; Willerson, JT1
Garan, H; Powell, WJ; Powers, ER; Ruskin, JN1
MORAN, NC1

Reviews

2 review(s) available for phenoxybenzamine and digoxin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
ADRENERGIC RECEPTORS WITHIN THE CARDIOVASCULAR SYSTEM.
    Circulation, 1963, Volume: 28

    Topics: Biochemical Phenomena; Biochemistry; Calcium; Cardiovascular System; Digoxin; Humans; Isoproterenol; Neurochemistry; Norepinephrine; Pharmacology; Phenoxybenzamine; Receptors, Adrenergic; Sympathetic Nervous System; Sympatholytics; Sympathomimetics; Theophylline

1963

Other Studies

9 other study(ies) available for phenoxybenzamine and digoxin

ArticleYear
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Neurogenic coronary vasoconstrictor effects of digitalis during acute global ischemia in dogs.
    The Journal of clinical investigation, 1977, Volume: 60, Issue:6

    Topics: Animals; Coronary Circulation; Coronary Disease; Coronary Vessels; Digoxin; Dogs; Phenoxybenzamine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Stimulation, Chemical; Strophanthins; Vascular Resistance; Ventricular Fibrillation

1977
Septic shock.
    Tropical doctor, 1979, Volume: 9, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Blood Coagulation; Digoxin; Drainage; Endotoxins; Female; Fluid Therapy; Heart Failure; Humans; Isoproterenol; Male; Middle Aged; Phenoxybenzamine; Shock, Septic; Water-Electrolyte Balance

1979
The neurogenic vasoconstrictor effect of digitalis on coronary vascular resistance.
    The Journal of clinical investigation, 1974, Volume: 53, Issue:1

    Topics: Blood Pressure; Chloralose; Coronary Vessels; Digitalis Glycosides; Digoxin; Heart Rate; Mecamylamine; Myocardium; Oxygen Consumption; Phenoxybenzamine; Time Factors; Urethane; Vascular Resistance

1974
Neural effect of digitalis glycosides on gracilis vascular resistance in hypotension.
    The American journal of physiology, 1980, Volume: 238, Issue:5

    Topics: Animals; Atropine; Blood Pressure; Digoxin; Dogs; Female; Hypotension; Male; Muscles; Phenoxybenzamine; Strophanthidin; Vascular Resistance

1980