phenoxybenzamine has been researched along with clozapine in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (58.82) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Campbell, WB; Harper, DC; Keeton, TK; Pettinger, WA | 1 |
| Ahlenius, S; Engel, J | 1 |
| Setler, P; Weidley, E; Zarevics, P | 1 |
| McMillen, BA; Shore, PA | 1 |
| Ljungberg, T | 1 |
| Palider, W; Przewlocka, B | 1 |
| Marsden, CD; Pycock, C; Tarsy, D | 1 |
| Chang, KJ; Ferris, RM; Russell, A; Tang, FL | 1 |
| Berggren, U; Engel, J; Liljequist, S | 1 |
| De Feo, G; Lisciani, R; Pavan, L; Samarelli, M; Valeri, P | 1 |
| Cools, AR; Ellenbroek, BA; Prinssen, EP | 1 |
1 review(s) available for phenoxybenzamine and clozapine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
16 other study(ies) available for phenoxybenzamine and clozapine
| Article | Year |
|---|---|
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Evidence for a renal alpha-adrenergic receptor inhibiting renin release.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Chlorisondamine; Clonidine; Clozapine; Hyponatremia; Juxtaglomerular Apparatus; Male; Methoxamine; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Receptors, Adrenergic; Renin; Sympathetic Nervous System | 1976 |
Potentiation by alpha-methyltyrosine of the suppression of food-reinforced lever-pressing behaviour induced by antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Catecholamines; Chlorpromazine; Clozapine; Conditioning, Operant; Drug Synergism; Feeding Behavior; Haloperidol; Male; Methyltyrosines; Phenoxybenzamine; Pimozide; Rats; Receptors, Adrenergic; Thioridazine | 1977 |
Blockade of intracranial self-stimulation by antipsychotic drugs: failure to correlate with central alpha-noradrenergic blockade.
Topics: Animals; Antipsychotic Agents; Chlorpromazine; Clozapine; Depression, Chemical; Electric Stimulation; Male; Muscle Contraction; Phenoxybenzamine; Pimozide; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Reflex; Self Stimulation; Thioridazine; Time Factors | 1977 |
Comparative effects of clozapine and alpha-adrenoceptor blocking drugs on regional noradrenaline metabolism in rat brain.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Cerebral Cortex; Clozapine; Dibenzazepines; Female; Hypothalamus; Methoxyhydroxyphenylglycol; Norepinephrine; Phenoxybenzamine; Rats; Time Factors | 1978 |
Reliability of two activity boxes commonly used to assess drug induced behavioural changes.
Topics: Animals; Apomorphine; Clozapine; Dextroamphetamine; Drug Interactions; Evaluation Studies as Topic; Humans; Male; Motor Activity; Phenoxybenzamine; Psychopharmacology; Rats; Reserpine; Stereotyped Behavior | 1978 |
The influence of LSD on the hind limb flexor reflex in the spinal rat.
Topics: Animals; Clozapine; Cyproheptadine; Electric Stimulation; Hindlimb; Lysergic Acid Diethylamide; Male; Methyltyrosines; Phenoxybenzamine; Rats; Reflex; Reserpine; Spinal Cord; Time Factors | 1975 |
Inhibition of circling behavior by neuroleptic drugs in mice with unilateral 6-hydroxydopamine lesions of the striatum.
Topics: Animals; Apomorphine; Basal Ganglia Diseases; Behavior; Biogenic Amines; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Chlorpromazine; Clozapine; Corpus Striatum; Dextroamphetamine; Diazepam; Dopamine; Haloperidol; Humans; Hydroxydopamines; Levodopa; Male; Metoclopramide; Mice; Motor Activity; Pentobarbital; Phenoxybenzamine; Pimozide; Promethazine; Stereotyped Behavior; Tranquilizing Agents | 1975 |
Evidence that the potential antipsychotic agent rimcazole (BW 234U) is a specific, competitive antagonist of sigma sites in brain.
Topics: Animals; Antipsychotic Agents; Apomorphine; Binding, Competitive; Brain; Carbazoles; Clozapine; Guinea Pigs; Kinetics; Male; Methylphenidate; Mice; Phenazocine; Phencyclidine; Phenoxybenzamine; Propranolol; Receptors, Opioid; Receptors, sigma; Sulpiride | 1986 |
The effect of catecholamine receptor antagonists on ethanol-induced locomotor stimulation.
Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Ethanol; Female; Haloperidol; Locomotion; Mice; Phenoxybenzamine; Pimozide; Receptors, Adrenergic; Receptors, Dopamine; Yohimbine | 1981 |
Possible dopaminergic involvement in biting compulsion induced by large doses of clonidine.
Topics: Aggression; Amphetamine; Animals; Clonidine; Clozapine; Dopamine; Drug Interactions; Female; Haloperidol; Humans; Male; Mice; Phenoxybenzamine; Scopolamine | 1983 |
Combined antagonism of adrenoceptors and dopamine and 5-HT receptors underlies the atypical profile of clozapine.
Topics: Adrenergic alpha-1 Receptor Antagonists; Analysis of Variance; Animals; Benzazepines; Clozapine; Disease Models, Animal; Dopamine Antagonists; Drug Synergism; Forelimb; Hindlimb; Ketanserin; Male; Pain Measurement; Phenoxybenzamine; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D1; Receptors, Serotonin | 1994 |