phenoxybenzamine and allopurinol

phenoxybenzamine has been researched along with allopurinol in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's0 (0.00)18.2507
2000's1 (7.69)29.6817
2010's6 (46.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Armstrong, DM; Fernando, AR; Griffiths, JR; Hendry, WF; O'Donoghue, EP; Perrett, D; Ward, JP; Wickham, JE1
Chatterjee, SN1
Kokas, P; Kupcsulik, P1
Ikai, I; Kamiyama, Y; Morimoto, T; Nakase, Y; Ozaki, N; Ozawa, K; Shimahara, Y; Tokunage, Y; Wakashiro, S; Yamaoka, Y1
Moberg, AW; Najarian, JS; Toledo-Pereyra, LH1
Campos, RA; Moberg, AW; Mozes, MF; Najarian, JS; Toledo-Pereyra, LH1

Reviews

2 review(s) available for phenoxybenzamine and allopurinol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacologic agents of potential value in protecting kidneys from ischemic damage.
    Transplantation proceedings, 1977, Volume: 9, Issue:3

    Topics: Adrenal Cortex Hormones; Allopurinol; Animals; Chlorpromazine; Dogs; Glutathione; Humans; Ischemia; Kidney; Kidney Transplantation; Magnesium Sulfate; Malonates; Organ Preservation; Oxamic Acid; Phenoxybenzamine; Rats; Tissue Preservation

1977

Other Studies

11 other study(ies) available for phenoxybenzamine and allopurinol

ArticleYear
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Enhanced preservation of the ischaemic kidney with inosine.
    Lancet (London, England), 1976, Mar-13, Volume: 1, Issue:7959

    Topics: Adenosine; Adenosine Triphosphate; Allopurinol; Animals; Creatinine; Cyclic AMP; Inosine; Ischemia; Kidney; Kidney Transplantation; Organ Preservation; Perfusion; Phenoxybenzamine; Rats; Rats, Inbred Strains; Tissue Preservation; Tissue Survival

1976
Ischemic damage of the liver. Part II: In vivo investigation of the prevention of the ischemic lesion of the liver.
    Acta hepato-gastroenterologica, 1979, Volume: 26, Issue:4

    Topics: Adenosine Triphosphate; Allopurinol; Animals; Aspartic Acid; Chlorides; Glucagon; Ischemia; Liver; Liver Regeneration; Magnesium; Methylprednisolone; Phenoxybenzamine; Rats

1979
Evaluation of cytoprotective drugs for liver preservation by pyridine nucleotide fluorometry.
    Surgery, 1988, Volume: 104, Issue:1

    Topics: Allopurinol; Animals; Cell Membrane; Chlorpromazine; Dibucaine; Epoprostenol; Liver; Male; Mitochondria, Liver; Organ Preservation; Oxidation-Reduction; Phenoxybenzamine; Prostaglandins, Synthetic; Pyrimidine Nucleotides; Rats; Rats, Inbred Strains

1988
Optimal management of warm ischemic kidneys prior to hypothermic preservation.
    Transplantation proceedings, 1974, Volume: 6, Issue:3

    Topics: Allopurinol; Animals; Cadaver; Cold Temperature; Diuretics; Dogs; Humans; Ischemia; Kidney; Kidney Transplantation; Methylprednisolone; Organ Preservation; Perfusion; Phenoxybenzamine; Phentolamine; Tissue Preservation

1974
Prevention of irreversible ischemic damage in renal preservation by pharmacological manipulation.
    Proceedings of the Clinical Dialysis and Transplant Forum, 1974, Issue:4

    Topics: Allopurinol; Animals; Chlorpromazine; Dogs; Hypothermia; Ischemia; Kidney Transplantation; Methylprednisolone; Phenoxybenzamine; Tissue Preservation; Tissue Survival; Transplantation, Autologous

1974