Page last updated: 2024-09-03

phenoxy radical and mocetinostat

phenoxy radical has been researched along with mocetinostat in 12 studies

Compound Research Comparison

Studies
(phenoxy radical)
Trials
(phenoxy radical)
Recent Studies (post-2010)
(phenoxy radical)
Studies
(mocetinostat)
Trials
(mocetinostat)
Recent Studies (post-2010) (mocetinostat)
22909121,7353908,606

Protein Interaction Comparison

ProteinTaxonomyphenoxy radical (IC50)mocetinostat (IC50)
Histone deacetylase 3Homo sapiens (human)0.7851
Nuclear receptor corepressor 1Homo sapiens (human)0.022
Cytochrome P450 3A4Homo sapiens (human)0.57
Cytochrome P450 2D6Homo sapiens (human)0.102
Cytochrome P450 2C19Homo sapiens (human)0.102
Histone deacetylase 4Homo sapiens (human)0.5717
Histone deacetylase 1Homo sapiens (human)0.3433
Histone deacetylase 7Homo sapiens (human)0.6725
Histone deacetylase 2Homo sapiens (human)0.3537
Histone deacetylase 11 Homo sapiens (human)0.6386
Histone deacetylase 8Homo sapiens (human)0.6725
Histone deacetylase 6Homo sapiens (human)0.5717
Histone deacetylase 5Homo sapiens (human)0.6725
Nuclear receptor corepressor 2Homo sapiens (human)0.045

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (33.33)18.2507
2000's8 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Claycamp, HG; Goldman, R; Kagan, VE; Stoyanovsky, DA1
Claycamp, HG; Day, BW; Goldman, R; Jonnalagadda, SS; Kagan, VE; Stoyanovosky, DA1
García Carmona, F; Núñez Delicado, E; Sánchez Ferrer, A1
Gmeiner, B; Held, I; Hermann, M; Hofbauer, R; Kapiotis, S; Seelos, C1
Kagan, VE; Kisin, ER; Kuzmenko, AI; Shvedova, AA; Tyurina, YY; Yalowich, JC1
Guo, Q; Packer, L1
Kagan, VE; Kuzmenko, AI; Matsura, T; Shvedova, AA; Tyurina, YY; Yalowich, JC1
Kagan, VE; Kisin, ER; Kuzmenko, AI; Li, R; Martin, I; Quinn, PJ; Shvedova, AA; Tyurin, VA; Tyurina, YY; Yalowich, JC1
O'Brien, PJ; Tafazoli, S; Wright, JS1
Burlingame, DJ; Colosi, LM; Huang, Q; Weber, WJ1
Cierniak, A; Elas, M; Kapiszewska, M; Lankoff, A1
Cuddihy, SL; Harwood, DT; Parker, A; Vissers, MC; Winterbourn, CC1

Other Studies

12 other study(ies) available for phenoxy radical and mocetinostat

ArticleYear
Phenoxyl radical-induced thiol-dependent generation of reactive oxygen species: implications for benzene toxicity.
    Archives of biochemistry and biophysics, 1995, Mar-10, Volume: 317, Issue:2

    Topics: Acridines; Benzene; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Deoxyguanosine; DNA; Electron Spin Resonance Spectroscopy; Glutathione; Horseradish Peroxidase; Hydrogen Peroxide; Luminescent Measurements; Monophenol Monooxygenase; Oxidation-Reduction; Peroxidase; Phenol; Phenols; Reactive Oxygen Species; Spin Labels; Sulfhydryl Compounds; Superoxides; Thioctic Acid

1995
Detection and characterization of the electron paramagnetic resonance-silent glutathionyl-5,5-dimethyl-1-pyrroline N-oxide adduct derived from redox cycling of phenoxyl radicals in model systems and HL-60 cells.
    Archives of biochemistry and biophysics, 1996, Jun-01, Volume: 330, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; HL-60 Cells; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oxidation-Reduction; Peroxidase; Phenols; Reactive Oxygen Species; Spectrophotometry, Ultraviolet; Spin Labels

1996
A kinetic study of the one-electron oxidation of Trolox C by the hydroperoxidase activity of lipoxygenase.
    Biochimica et biophysica acta, 1997, Apr-17, Volume: 1335, Issue:1-2

    Topics: Antioxidants; Chromans; Hydrogen Peroxide; Kinetics; Lipoxygenase; Oxidation-Reduction; Peroxidase; Phenols; Spectrophotometry, Ultraviolet; Vitamin E

1997
Salicylate promotes myeloperoxidase-initiated LDL oxidation: antagonization by its metabolite gentisic acid.
    Free radical biology & medicine, 1999, Volume: 26, Issue:9-10

    Topics: Arteriosclerosis; Aspirin; Free Radical Scavengers; Free Radicals; Gentisates; Humans; Hydroxybenzoates; In Vitro Techniques; Lipid Peroxidation; Lipoproteins, LDL; Neutrophils; Oxidants; Oxidation-Reduction; Peroxidase; Phenols; Salicylic Acid; Tyrosine

1999
Myeloperoxidase-catalyzed phenoxyl radicals of vitamin E homologue, 2,2,5,7,8-pentamethyl- 6-hydroxychromane, do not induce oxidative stress in live HL-60 cells.
    Biochemical and biophysical research communications, 2000, Apr-21, Volume: 270, Issue:3

    Topics: Cell Survival; Chromans; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; HL-60 Cells; Humans; Hydrogen Peroxide; Kinetics; Oxidative Stress; Peroxidase; Phenols

2000
Ascorbate-dependent recycling of the vitamin E homologue Trolox by dihydrolipoate and glutathione in murine skin homogenates.
    Free radical biology & medicine, 2000, Volume: 29, Issue:3-4

    Topics: Animals; Antioxidants; Ascorbic Acid; Cell Extracts; Chromans; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Hydrogen Peroxide; Kinetics; Mice; Peroxidase; Phenols; Skin; Thioctic Acid; Vitamin E

2000
Pro-oxidant and antioxidant mechanisms of etoposide in HL-60 cells: role of myeloperoxidase.
    Cancer research, 2001, Nov-01, Volume: 61, Issue:21

    Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Biotransformation; DNA Topoisomerases, Type II; DNA, Neoplasm; Electron Spin Resonance Spectroscopy; Etoposide; Free Radicals; HL-60 Cells; Humans; Hydrogen Peroxide; Lipid Peroxidation; Oxidation-Reduction; Peroxidase; Phenols; Phospholipids; Reactive Oxygen Species

2001
Direct evidence for recycling of myeloperoxidase-catalyzed phenoxyl radicals of a vitamin E homologue, 2,2,5,7,8-pentamethyl-6-hydroxy chromane, by ascorbate/dihydrolipoate in living HL-60 cells.
    Biochimica et biophysica acta, 2003, Mar-17, Volume: 1620, Issue:1-3

    Topics: Antioxidants; Ascorbic Acid; Cell Survival; Chromans; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Free Radicals; HL-60 Cells; Humans; Hydrogen Peroxide; Oxidation-Reduction; Peroxidase; Phenols; Spectrophotometry; Substrate Cycling; Thioctic Acid

2003
Prooxidant and antioxidant activity of vitamin E analogues and troglitazone.
    Chemical research in toxicology, 2005, Volume: 18, Issue:10

    Topics: Animals; Antioxidants; Cell Survival; Cell-Free System; Chromans; Glutathione; Hepatocytes; Hydrogen Peroxide; Lipid Peroxidation; Male; Microsomes, Liver; Oxidants; Oxidation-Reduction; Peroxidase; Phenols; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Thiazolidinediones; Tocopherols; Troglitazone; Vitamin E

2005
Peroxidase-mediated removal of a polychlorinated biphenyl using natural organic matter as the sole cosubstrate.
    Environmental science & technology, 2007, Feb-01, Volume: 41, Issue:3

    Topics: Adsorption; Anisoles; Benzopyrans; Biodegradation, Environmental; Catalysis; Environmental Pollutants; Hydrophobic and Hydrophilic Interactions; Oxidation-Reduction; Peroxidase; Phenol; Phenols; Polychlorinated Biphenyls; Time Factors; Water Purification

2007
Lifespan of etoposide-treated human neutrophils is affected by antioxidant ability of quercetin.
    Toxicology in vitro : an international journal published in association with BIBRA, 2007, Volume: 21, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Cell Survival; Cells, Cultured; DNA Damage; Etoposide; Humans; Hydrogen Peroxide; Neutrophils; Peroxidase; Phenols; Quercetin; Reactive Oxygen Species

2007
Ascorbate interacts with reduced glutathione to scavenge phenoxyl radicals in HL60 cells.
    Free radical biology & medicine, 2008, Apr-15, Volume: 44, Issue:8

    Topics: Ascorbic Acid; Buthionine Sulfoximine; Cyclic N-Oxides; Free Radical Scavengers; Glutathione; HL-60 Cells; Humans; Hydrogen Peroxide; Lipid Peroxidation; Peroxidase; Phenol; Phenols; Spin Trapping

2008