phenoxy radical has been researched along with etoposide in 8 studies
| Studies (phenoxy radical) | Trials (phenoxy radical) | Recent Studies (post-2010) (phenoxy radical) | Studies (etoposide) | Trials (etoposide) | Recent Studies (post-2010) (etoposide) |
|---|---|---|---|---|---|
| 229 | 0 | 91 | 18,306 | 3,693 | 4,900 |
| Protein | Taxonomy | phenoxy radical (IC50) | etoposide (IC50) |
|---|---|---|---|
| nuclear receptor coactivator 1 isoform 1 [Homo sapiens] | Homo sapiens (human) | 1.153 | |
| nuclear receptor coactivator 3 isoform a | Homo sapiens (human) | 1.4284 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 3.187 | |
| Caspase-3 | Homo sapiens (human) | 1 | |
| DNA topoisomerase 2-beta | Homo sapiens (human) | 0.4299 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 4.18 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (75.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bets, D; Horn, IR; Lafleur, MV; Lankelma, J; Mans, DR; Retèl, J; Schuurhuis, GJ; Westmijze, EJ | 1 |
| Goldman, R; Kagan, VE; Menshikova, EV; Ritov, VB; Stoyanovsky, DA | 1 |
| Gantchev, TG; Kagan, VE; Stoyanovsky, DA; van Lier, JE; Yalowich, JC | 1 |
| Day, BW; Gantchev, TG; Goldman, R; Kagan, VE; Stoyanovsky, DA; Yalowich, JC | 1 |
| Gantchev, T; Kagan, V; Stoyanovsky, D; Yalowich, J | 1 |
| Goldman, R; Grogan, J; Kagan, VE; Tsyrlov, IB | 1 |
| Kagan, VE; Kuzmenko, AI; Matsura, T; Shvedova, AA; Tyurina, YY; Yalowich, JC | 1 |
| Cierniak, A; Elas, M; Kapiszewska, M; Lankoff, A | 1 |
8 other study(ies) available for phenoxy radical and etoposide
| Article | Year |
|---|---|
Reactions of glutathione with the catechol, the ortho-quinone and the semi-quinone free radical of etoposide. Consequences for DNA inactivation.
Topics: Bacteriophage phi X 174; Catechols; Chromatography, High Pressure Liquid; DNA; DNA, Single-Stranded; Electron Spin Resonance Spectroscopy; Etoposide; Free Radicals; Glutathione; Phenols; Quinones | 1992 |
Antioxidant paradoxes of phenolic compounds: peroxyl radical scavenger and lipid antioxidant, etoposide (VP-16), inhibits sarcoplasmic reticulum Ca(2+)-ATPase via thiol oxidation by its phenoxyl radical.
Topics: Alamethicin; Amidines; Animals; Antioxidants; Calcium-Transporting ATPases; Catalase; Electron Spin Resonance Spectroscopy; Etoposide; Fatty Acids, Unsaturated; Free Radical Scavengers; Free Radicals; Kinetics; Luminescent Measurements; Muscle, Skeletal; Oxidation-Reduction; Phenols; Rabbits; Sarcoplasmic Reticulum; Spectrometry, Fluorescence; Superoxide Dismutase; Time Factors | 1995 |
Interactions of phenoxyl radical of antitumor drug, etoposide, with reductants in solution and in cell and nuclear homogenates: electron spin resonance and high-performance liquid chromatography.
Topics: Antioxidants; Ascorbic Acid; Azo Compounds; Cell Line; Cell Nucleus; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Etoposide; Free Radicals; Glutathione; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Molecular Structure; Monophenol Monooxygenase; Phenols; Tumor Cells, Cultured | 1994 |
Ascorbate is the primary reductant of the phenoxyl radical of etoposide in the presence of thiols both in cell homogenates and in model systems.
Topics: Animals; Ascorbic Acid; Electron Spin Resonance Spectroscopy; Etoposide; Free Radicals; Liver; Male; Monophenol Monooxygenase; Oxidation-Reduction; Phenols; Rats; Rats, Sprague-Dawley; Retina; Subcellular Fractions; Sulfhydryl Compounds; Thioctic Acid | 1994 |
Tyrosinase-induced phenoxyl radicals of etoposide (VP-16): interaction with reductants in model systems, K562 leukemic cell and nuclear homogenates.
Topics: Ascorbic Acid; Cell Nucleus; Chromatography, High Pressure Liquid; Deferoxamine; Electron Spin Resonance Spectroscopy; Etoposide; Free Radicals; Glutathione; Humans; Leukemia; Monophenol Monooxygenase; Oxidation-Reduction; Phenols; Thioctic Acid; Tumor Cells, Cultured | 1993 |
Reactions of phenoxyl radicals with NADPH-cytochrome P-450 oxidoreductase and NADPH: reduction of the radicals and inhibition of the enzyme.
Topics: Animals; Antioxidants; Binding Sites; Chromans; Dithionitrobenzoic Acid; Electron Spin Resonance Spectroscopy; Etoposide; Free Radicals; Humans; Kinetics; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Phenol; Phenols; Recombinant Proteins; Spodoptera; Transfection | 1997 |
Pro-oxidant and antioxidant mechanisms of etoposide in HL-60 cells: role of myeloperoxidase.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Biotransformation; DNA Topoisomerases, Type II; DNA, Neoplasm; Electron Spin Resonance Spectroscopy; Etoposide; Free Radicals; HL-60 Cells; Humans; Hydrogen Peroxide; Lipid Peroxidation; Oxidation-Reduction; Peroxidase; Phenols; Phospholipids; Reactive Oxygen Species | 2001 |
Lifespan of etoposide-treated human neutrophils is affected by antioxidant ability of quercetin.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Cell Survival; Cells, Cultured; DNA Damage; Etoposide; Humans; Hydrogen Peroxide; Neutrophils; Peroxidase; Phenols; Quercetin; Reactive Oxygen Species | 2007 |