Page last updated: 2024-09-02

phenoxazinone and metyrapone

phenoxazinone has been researched along with metyrapone in 2 studies

Compound Research Comparison

Studies
(phenoxazinone)
Trials
(phenoxazinone)
Recent Studies (post-2010)
(phenoxazinone)
Studies
(metyrapone)
Trials
(metyrapone)
Recent Studies (post-2010) (metyrapone)
550173,415128250

Protein Interaction Comparison

ProteinTaxonomyphenoxazinone (IC50)metyrapone (IC50)
Cytochrome P450 1A2Homo sapiens (human)4.8
Cytochrome P450 3A4Homo sapiens (human)2.8659
Cytochrome P450 2C8Homo sapiens (human)5
Cytochrome P450 2D6Homo sapiens (human)4.6
Cytochrome P450 11B1, mitochondrial Bos taurus (cattle)7.83
Cytochrome P450 11B1, mitochondrialRattus norvegicus (Norway rat)4.7357
Cytochrome P450 11B1, mitochondrialHomo sapiens (human)0.0181
Cytochrome P450 11B2, mitochondrialHomo sapiens (human)0.0838
Cytochrome P450 2C19Homo sapiens (human)5

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fantel, AG; Juchau, MR; Lee, QH1
Burke, MD; Mayer, RT; Rawlins, MD; Rettie, AE; Williams, FM1

Other Studies

2 other study(ies) available for phenoxazinone and metyrapone

ArticleYear
Human embryonic cytochrome P450S: phenoxazone ethers as probes for expression of functional isoforms during organogenesis.
    Biochemical pharmacology, 1991, Nov-27, Volume: 42, Issue:12

    Topics: Antibodies, Monoclonal; Benzoflavones; Biotransformation; Carbon Monoxide; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Embryo, Mammalian; Ethers; Humans; Isoenzymes; Metyrapone; Morphogenesis; Orphenadrine; Oxazines; Oxidoreductases; Xenobiotics

1991
Major differences between lung, skin and liver in the microsomal metabolism of homologous series of resorufin and coumarin ethers.
    Biochemical pharmacology, 1986, Oct-15, Volume: 35, Issue:20

    Topics: Animals; Benzoflavones; Coumarins; Female; Lung; Metyrapone; Mice; Mice, Inbred BALB C; Microsomes; Microsomes, Liver; Oxazines; Skin; Structure-Activity Relationship

1986
chemdatabank.com