phenobarbital has been researched along with zoxazolamine in 68 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 62 (91.18) | 18.7374 |
| 1990's | 2 (2.94) | 18.2507 |
| 2000's | 3 (4.41) | 29.6817 |
| 2010's | 1 (1.47) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Conney, AH; Jerina, DM; Levin, W; Tomaszewski, JE | 1 |
| Heath, D; Kay, JM; Smith, P; Will, JA | 1 |
| Jaeger, RJ; Moslen, MT; Reynolds, ES; Szabo, S | 1 |
| Chow, CP; Cornish, HH | 1 |
| Hrdlicka, J; Lee, JS; Seawright, AA | 1 |
| de Matteis, F; Unseld, A | 1 |
| Baird, MB; Massie, HR; Nicolosi, RJ; Samis, HV | 1 |
| Felton, JS; Nebert, DW | 1 |
| Kourounakis, P; Ship, S | 1 |
| Garg, BD; Kourounakis, P; Kovacs, K; Szabo, S; Tuchweber, B | 1 |
| Carr, GS; Mathur, PP; Reavey-Cantwell, NH; Smyth, RD; Witmer, CM | 1 |
| Elliot, S; Gelboin, HV; Waters, HL; Wiebel, FJ | 1 |
| Drew, R; Priestly, BG | 1 |
| Garg, BD; Salas, M; Tuchweber, B | 1 |
| McDevitt, DG; Nies, AS; Rush, BD; Strother, JR; Wilkinson, GR | 1 |
| Dutton, G; Hänninen, O; Marselos, M | 1 |
| Doki, M; Puga, FR; Rodrigues, MA | 1 |
| Kato, R; Takanaka, A | 2 |
| Arnold, K; Gerber, N | 1 |
| Klaassen, CD | 3 |
| Kato, R; Omori, Y; Onoda, K; Takanaka, A | 1 |
| Fouts, JR; Peters, MA | 1 |
| Century, B | 1 |
| Kocsis, JJ; Saito, FU; Snyder, R | 1 |
| Back, KC; Murphy, JP; Van Stee, EW | 1 |
| Momose, S; Takagaki, E; Tanayama, S | 1 |
| Burns, JJ | 2 |
| Buu-Hoï, NP; Hien, DP; Saint-Ruf, G; Servoin-Sidoine, J | 1 |
| Gautieri, RF; Mitala, JJ | 1 |
| Johnson, EA; Stenger, RJ | 2 |
| Lavigne, JG; Marchand, C | 1 |
| Bousquet, WF; Hatfield, GK; Miya, TS | 1 |
| Brodeur, J; Marchand, C | 1 |
| Arcos, JC; Argus, MF; Venkatesan, N | 1 |
| Brase, DA; Westfall, TC | 1 |
| Abernathy, CO; Guthrie, FE; Hodgson, E; Philpot, RM | 1 |
| Kato, R | 2 |
| Kato, R; Oshima, T; Takanaka, A | 1 |
| Kato, R; Oshima, T; Takayanagi, M | 1 |
| Dehn, F; LeValley, SE; Lombrozo, L; Mitoma, C | 1 |
| Kato, R; Takanaka, A; Takayanaghi, M | 1 |
| Wilson, JT | 1 |
| Dixon, RL; Willson, VJ | 1 |
| Breckenridge, A; Davies, DS; Orme, ML; Thorgeirsson, S | 1 |
| Becker, BA; Harbison, RD | 1 |
| Costa, E; Groppetti, A | 1 |
| Fouts, JR; Gram, TE | 1 |
| Fouts, JR; Gram, TE; Rogers, LA | 1 |
| Bender, AD; Greene, L; Macko, E; Tedeschi, RE; Wilfon, G | 1 |
| de Montigny, C; Debonnel, G; Monnet, FP | 1 |
| Chappel, CI; Procter, BG | 1 |
| Egan-Hafley, M; Liang, S; Moore, DD; Wei, P; Zhang, J | 1 |
| CHIESARA, E; KATO, R; VASSANELLI, P | 1 |
| BURNS, JJ; CONNEY, AH | 1 |
| GILLETTE, JR | 1 |
| MANNERING, GJ; RUBIN, A; TEPHLY, TR | 1 |
| BOUSQUET, WF; MIYA, TS; RUPE, BD | 1 |
| CRAM, RL; FOUTS, JR; JUCHAU, MR | 1 |
| BURNS, JJ; CONNEY, AH; CUCINELL, SA; KOSTER, R | 1 |
| Ahmed, MR; Guo, D; Jia, Y; Qi, C; Rao, MS; Reddy, JK; Sarkar, J; Usuda, N; Viswakarma, N | 1 |
1 review(s) available for phenobarbital and zoxazolamine
| Article | Year |
|---|---|
IMPLICATIONS ON ENZYME INDUCTION FOR DRUG THERAPY.
Topics: Animals; Benzopyrenes; Cyclizine; Dicumarol; Diphenhydramine; Dogs; Drug Therapy; Enzyme Induction; Enzymes; Glutethimide; Hexobarbital; Liver; Meprobamate; Metabolism; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Probenecid; Rats; Research; Tolbutamide; Toxicology; Zoxazolamine | 1964 |
67 other study(ies) available for phenobarbital and zoxazolamine
| Article | Year |
|---|---|
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A highly sensitive radiometric assay for zoxazolamine hydroxylation by liver microsomal cytochrome P-450 and P-448: properties of the membrane-bound and purified reconstituted system.
Topics: Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Cytochromes; Enzyme Induction; Hydrogen-Ion Concentration; Kinetics; Membranes; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Pregnenolone; Rats; Tritium; Zoxazolamine | 1976 |
Effects of phenobarbitone, cinnarizine, and zoxazolamine on the development of right ventricular hypertrophy and hypertensive pulmonary vascular disease in rats treated with monocrotaline.
Topics: Animals; Cardiomegaly; Cinnarizine; Hypertension, Pulmonary; Male; Phenobarbital; Piperazines; Pyrrolizidine Alkaloids; Rats; Zoxazolamine | 1976 |
Vinyl chloride-induced deactivation of cytochrome P-450 and other components of the liver mixed function oxidase system: an in vivo study.
Topics: Alanine Transaminase; Aminopyrine N-Demethylase; Animals; Aroclors; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Enzyme Activation; Ethylmorphine-N-Demethylase; Glucose-6-Phosphatase; Glutathione; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Organ Size; Oxidoreductases; Phenobarbital; Rats; Vinyl Chloride; Vinyl Compounds; Zoxazolamine | 1975 |
Effects of lead on the induction of hepatic microsomal enzymes by phenobarbital and 3,4-benzpyrene.
Topics: Animals; Benzopyrenes; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Drug Interactions; Enzyme Induction; In Vitro Techniques; Lead; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Paralysis; Phenobarbital; Porphobilinogen Synthase; Rats; Time Factors; Zoxazolamine | 1978 |
The effect of size and timing of a pretreatment dose of phenobarbitone on the liver lesion caused by ngaione in the mouse.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Furans; Liver Diseases; Male; Mice; Microsomes, Liver; Oils, Volatile; Oxidoreductases; Phenobarbital; Sesquiterpenes; Time Factors; Zoxazolamine | 1979 |
Destruction of endogenous and exogenous haem by 2-allyl-2-isopropylacetamide: role of the liver cytochrome P-450 which is inducible by phenobarbitone.
Topics: Acetamides; Allylisopropylacetamide; Aminolevulinic Acid; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Heme; Hexobarbital; Male; Methylcholanthrene; Microsomes, Liver; Paralysis; Phenobarbital; Rats; Sleep; Zoxazolamine | 1978 |
Microsomal mixed-function oxidase activity and senescence-I. Hexobarbital sleep time and induction of components of the hepatic microsomal enzyme system in rats of different ages.
Topics: Age Factors; Aging; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Hexobarbital; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Phenobarbital; Rats; Sleep; Spectrum Analysis; Time Factors; Zoxazolamine | 1975 |
Importance of genetic factors influencing the metabolism of foreign compounds.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Laboratory; Aryl Hydrocarbon Hydroxylases; Benzopyrenes; Biotransformation; Drosophila; Enzyme Induction; Genes, Dominant; Genes, Regulator; Genotype; Methylcholanthrene; Mice; Mice, Inbred Strains; Models, Biological; Oxygenases; Phenobarbital; Species Specificity; Zoxazolamine | 1976 |
Influence of combined treatment with pregnenolone-16alpha-carbonitrile and spironolactone or phenobarbital on drug metabolism in rats.
Topics: Animals; Dose-Response Relationship, Drug; Female; Microsomes, Liver; Nitriles; Phenobarbital; Pregnenolone; Rats; Spironolactone; Zoxazolamine | 1977 |
Studies on drug metabolism and liver ultrastructure after conjoint treatment with pregnenolone-16alpha-carbonitrile and dl-ethionine.
Topics: Animals; Digitoxin; Drug Interactions; Ethionine; Female; Hexobarbital; In Vitro Techniques; Liver; Microscopy, Electron; Paralysis; Pharmaceutical Preparations; Phenobarbital; Pregnenolone Carbonitrile; Rats; Seizures; Sleep; Zoxazolamine | 1977 |
Temporal pattern and reversal of impaired hepatic mono-oxygenases by phenobarbital in rats with developing and established adjuvant disease.
Topics: Animals; Arthritis; Arthritis, Experimental; Cytochromes; Hexobarbital; Male; Microsomes, Liver; Oxygenases; Paralysis; Phenobarbital; Rats; Sleep; Time Factors; Zoxazolamine | 1977 |
Effect of 7 8-benzoflavone on the duration of zoxazolamine paralysis and hexobarbital hypnosis in rats.
Topics: Animals; Depression, Chemical; Flavonoids; Hexobarbital; Male; Methylcholanthrene; Paralysis; Phenobarbital; Rats; Sleep; Time Factors; Zoxazolamine | 1976 |
Hexobarbital sleeping time and drug metabolism in rats with ligated bile ducts--a lack of correlation.
Topics: Animals; Bile Ducts; Hexobarbital; Male; Microsomes, Liver; Mixed Function Oxygenases; Pharmaceutical Preparations; Phenobarbital; Proadifen; Protein Binding; Rats; Sleep; Thiopental; Time Factors; Zoxazolamine | 1976 |
Microsomal enzyme inducers and hypervitaminosis A in rats.
Topics: Animals; Bone Diseases; Enzyme Induction; Female; Liver; Microsomes, Liver; Paralysis; Phenobarbital; Phenytoin; Pregnenolone Carbonitrile; Rats; Vitamin A; Zoxazolamine | 1976 |
Effects of alteration of hepatic microsomal enzyme activity on liver blood flow in the rat.
Topics: Animals; Benzopyrenes; Cardiac Output; Enzyme Induction; Hemodynamics; Liver Circulation; Male; Methylcholanthrene; Microsomes, Liver; Microspheres; Phenobarbital; Proadifen; Rats; Zoxazolamine | 1976 |
Evidence that D-glucaro-1,4-lactone shortens the pharmacological action of drugs being disposed via the bile as glucuronides.
Topics: Animals; Bile; Depression, Chemical; Drug Interactions; Glucaric Acid; Glucuronates; Glucuronidase; In Vitro Techniques; Intestines; Lactones; Male; Mice; Motor Activity; Pharmaceutical Preparations; Phenobarbital; Progesterone; Rats; Rats, Inbred Strains; Sugar Acids; Zoxazolamine | 1975 |
Effects of phenobarbital, chlordane, and oxytetracycline on DDT excretion in rats.
Topics: Animals; Bile; Chlordan; DDT; Male; Oxytetracycline; Paralysis; Phenobarbital; Rats; Rats, Inbred Strains; Time Factors; Zoxazolamine | 1986 |
Effect of starvation on the in vivo metabolism and effect of drugs in female and male rats.
Topics: Amides; Anesthesia; Animals; Barbiturates; Body Weight; Carisoprodol; Diphosphates; Female; Hexobarbital; Kidney; Liver; Male; Organ Size; Paralysis; Pentobarbital; Phenobarbital; Rats; Starvation; Strychnine; Sucrose; Zoxazolamine | 1967 |
The effect of diphenyl-piperazine compounds and other agents on diphenylhydantoin, zoxazolamine and hexobarbital metabolism.
Topics: Animals; Benzopyrenes; Cyclizine; DDT; Diphenhydramine; Endoplasmic Reticulum; Hexobarbital; Humans; Hydroxyzine; Liver; Male; Meclizine; Methylcholanthrene; Mice; Microscopy, Electron; Phenethylamines; Phenobarbital; Phenytoin; Piperazines; Trifluoperazine; Zoxazolamine | 1968 |
Biliary flow after microsomal enzyme induction.
Topics: Animals; Benzopyrenes; Bile; Chlordan; Enzyme Induction; Liver; Methylcholanthrene; Microsomes; Nikethamide; Organ Size; Phenobarbital; Phenylbutazone; Piperazines; Rats; Zoxazolamine | 1969 |
Ethanol metabolism in rats after microsomal metabolizing enzyme induction.
Topics: Animals; Chlordan; Enzyme Induction; Ethanol; Liver; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Piperazines; Rats; Stimulation, Chemical; Zoxazolamine | 1969 |
Different effect of aflatoxin on the induction of tryptophan oxygenase and of microsomal drug-hydroxylase system.
Topics: Aflatoxins; Animals; Cytochromes; Enzyme Induction; Female; Hexobarbital; Hydrocortisone; Methylcholanthrene; Microsomes; Mixed Function Oxygenases; Phenobarbital; Pigments, Biological; Rats; Tryptophan Oxygenase; Tyrosine Transaminase; Zoxazolamine | 1970 |
The influence of magnesium and some other divalent cations on hepatic microsomal drug metabolism in vitro.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Calcium; Chlorides; Cobalt; Copper; Cytochromes; Edetic Acid; Hexobarbital; In Vitro Techniques; Iron; Magnesium; Male; Manganese; Microsomes, Liver; NADP; Nitrophenols; Phenobarbital; Potassium; Rats; Strontium; Sulfates; Zinc; Zoxazolamine | 1970 |
Effect of microsomal enzyme inducers on the biliary excretion of cardiac glycosides.
Topics: Analysis of Variance; Animals; Bile; Biotransformation; Cardiac Glycosides; Digitoxin; Digoxin; Dose-Response Relationship, Drug; Enzyme Induction; Lethal Dose 50; Liver; Male; Methylcholanthrene; Microsomes; Myocardium; Organ Size; Ouabain; Paralysis; Phenobarbital; Pregnenolone Carbonitrile; Rats; Spironolactone; Time Factors; Tritium; Zoxazolamine | 1974 |
A role of the dietary lipid in the ability of phenobarbital to stimulate drug detoxification.
Topics: Aminopyrine; Animals; Biotransformation; Chlorpromazine; Dietary Fats; Fatty Acids; Female; Glucosephosphate Dehydrogenase; Hexobarbital; In Vitro Techniques; Lipids; Liver; Mice; Mice, Inbred ICR; Microsomes, Liver; Phenobarbital; Rats; Sleep; Time Factors; Zoxazolamine | 1973 |
Effect of benzene on hepatic drug metabolism and ultrastructure.
Topics: Animals; Azo Compounds; Benzene; Benzene Derivatives; Benzoates; Body Weight; Carbon Radioisotopes; Endoplasmic Reticulum; Hexobarbital; Liver; Male; Microscopy, Electron; Microsomes, Liver; Naphthalenesulfonates; Nitro Compounds; Organ Size; Phenobarbital; Rats; Time Factors; Zoxazolamine | 1973 |
Effect of dibromotetrafluoroethane inhalation on hepatic drug metabolism in mice.
Topics: Animals; Chlorofluorocarbons, Methane; Drug Interactions; Hexobarbital; Hydrocarbons, Halogenated; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Paralysis; Phenobarbital; Proadifen; Respiration; Sleep; Time Factors; Zoxazolamine | 1973 |
Metabolism of 8-chloro-6-phenyl-4H-s-triazole(4,3-a)(1,4)benzodiazepine (D-40TA), a new central depressant. 3. Metabolism and tolerance studies in rats.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzazepines; Brain; Carbon Radioisotopes; Chlordiazepoxide; Drug Tolerance; Heart; Intestine, Small; Kidney; Lung; Male; Muscle Relaxants, Central; Myocardium; Nitrazepam; Phenobarbital; Rats; Spinal Cord; Time Factors; Triazoles; Zoxazolamine | 1974 |
Interaction of environmental agents and drugs.
Topics: Animals; Anticoagulants; Antipyrine; Benzopyrenes; Chlordan; DDT; Dogs; Environment; Environmental Exposure; Enzyme Induction; Haplorhini; Humans; Male; Microsomes, Liver; Pharmaceutical Preparations; Pharmacology; Phenobarbital; Phenylbutazone; Rats; Toxicology; Zoxazolamine | 1969 |
[Canceromimetic properties of the tetrachloro-2,3,7,8 dibenzo-p-dioxin ("dioxin")].
Topics: Animals; Arginase; Carcinogens; Dioxins; Enzyme Induction; Glycolates; Liver; Liver Neoplasms; Male; Mice; Microsomes, Liver; Mixed Function Oxygenases; Paralysis; Phenobarbital; Phenols; Rats; Sleep; Time Factors; Zoxazolamine | 1971 |
Apparent enzyme inhibition through enzyme-induction studies as a possible mode of action of certain cobalt compounds.
Topics: Animals; Chlorides; Cobalt; Enzyme Induction; Enzyme Inhibitors; Female; Hexobarbital; Mice; Nitrites; Phenobarbital; Sleep; Zoxazolamine | 1971 |
Modifying effect of 3-amino-1,2,4-triazole on phenobarbital-induced changes in rat liver.
Topics: Amitrole; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cytochromes; Drug Antagonism; Endoplasmic Reticulum; Enzyme Induction; Herbicides; Liver; Liver Diseases; Male; Microscopy, Electron; Microsomes, Liver; Necrosis; Paralysis; Phenobarbital; Rats; Triazoles; Zoxazolamine | 1972 |
Effects of phenobarbital pretreatment on the response of rat liver to halothane administration.
Topics: Anesthesia, General; Animals; Chemical and Drug Induced Liver Injury; Cytochromes; Enzyme Induction; Halothane; Liver; Male; Microsomes, Liver; Necrosis; Paralysis; Phenobarbital; Preanesthetic Medication; Rats; Rats, Inbred Strains; Zoxazolamine | 1972 |
Effects of phenobarbital pretreatment on rat pancreas.
Topics: Amylases; Animals; Atropine; Carbon Isotopes; Enzyme Induction; Female; Hexobarbital; In Vitro Techniques; Leucine; Lipase; Microsomes; Mixed Function Oxygenases; Morphinans; Organ Size; Oxidoreductases; Pancreas; Phenobarbital; Protein Biosynthesis; Proteins; Rats; Rats, Inbred Strains; Ribonucleases; Zoxazolamine | 1972 |
Ethanol tolerance and ethanol-drug interactions in the rat.
Topics: Animals; Barbiturates; Behavior, Animal; Body Weight; Depression, Chemical; Drug Interactions; Drug Tolerance; Ethanol; Female; Hexobarbital; Injections, Intraperitoneal; Male; Meprobamate; Motor Activity; Organ Size; Pentobarbital; Phenobarbital; Rats; Rats, Inbred Strains; Zoxazolamine | 1972 |
Effect of splenectomy on the activity of drug-metabolizing enzymes in the liver of rats.
Topics: Animals; Anisoles; Biological Assay; Carbon Isotopes; Cytochromes; Enzyme Induction; Female; Hexobarbital; Leucine; Liver; Liver Circulation; Microsomes, Liver; Nitroso Compounds; Paralysis; Parathion; Phenobarbital; Rats; Sleep; Spleen; Splenectomy; Time Factors; Zoxazolamine | 1971 |
Induction and repression of microsomal drug-metabolizing enzymes by polycyclic hydrocarbons and phenobarbital: theoretical models.
Topics: Allosteric Regulation; Animals; Benz(a)Anthracenes; Benzopyrenes; Chlordan; Enzyme Induction; Enzyme Repression; Ethionine; Fluorenes; Genes, Regulator; Hexobarbital; Meperidine; Methylcholanthrene; Microsomes, Liver; Models, Biological; Operon; Oxidoreductases; Phenobarbital; Rats; Zoxazolamine | 1971 |
Studies on the mechanism of tolerance to nicotine-induced elevations of urinary catecholamines.
Topics: Adrenal Glands; Animals; Carbon Isotopes; Catechol O-Methyltransferase; Catecholamines; Catechols; Drug Tolerance; Enzyme Induction; Fluorometry; Heart; Hexobarbital; In Vitro Techniques; Liver; Male; Metabolism; Methylcholanthrene; Methyltransferases; Monoamine Oxidase; Myocardium; Nerve Endings; Nicotine; Norepinephrine; Oxidoreductases; Perfusion; Phenobarbital; Rats; S-Adenosylmethionine; Sleep; Time Factors; Tritium; Zoxazolamine | 1971 |
Inductive effects of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane(DDT), phenobarbital, and benzpyrene on microsomal cytochrome B450, ethyl isocyanide spectra, and metabolism in vivo of zoxazolamine and hexobarbital in the mouse.
Topics: Animals; Benzopyrenes; Cyanides; Cytochrome P-450 Enzyme System; DDT; Enzyme Induction; Hexobarbital; Male; Mice; Microsomes, Liver; Paralysis; Phenobarbital; Proteins; Sleep; Spectrum Analysis; Time Factors; Zoxazolamine | 1971 |
Effect of administration of 3-aminotriazole on the activity of microsomal drug-metabolizing enzyme systems of rat liver.
Topics: Aminopyrine; Aniline Compounds; Animals; Blood Proteins; Brain; Brain Chemistry; Cytochromes; Female; Hexobarbital; Liver; Male; Methylcholanthrene; Microsomes; Nitrobenzenes; Pentobarbital; Phenobarbital; Pigments, Biological; Rats; Spectrophotometry; Triazoles; Zoxazolamine | 1967 |
Contrastic effects of ethionine and carbontetrachloride on ascorbic acid metabolism and on the activity of microsomal drug-metabolizing enzymes in rats.
Topics: Analysis of Variance; Animals; Ascorbic Acid; Carbon Tetrachloride; Chlorobutanol; Ethionine; Female; Injections, Intraperitoneal; Kidney; Liver; Meprobamate; Methylcholanthrene; Microsomes; Phenobarbital; Rats; Zoxazolamine | 1967 |
Drug metabolism in tumor-bearing rats. II. In vivo metabolisms and effects of drugs in tumor-bearing rats.
Topics: Anesthesia; Animals; Carcinoma 256, Walker; Carisoprodol; Cholinesterase Inhibitors; Female; Injections, Intraperitoneal; Liver; Male; Paralysis; Phenobarbital; Rats; Sex Factors; Statistics as Topic; Strychnine; Zoxazolamine | 1968 |
Metabolism of drugs in old rats. II. Metabolism in vivo and effect of drugs in old rats.
Topics: Aging; Anesthesia; Animals; Carisoprodol; Female; Hexobarbital; Injections, Intraperitoneal; Insecticides; Liver; Male; Microsomes; Paralysis; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Rats; Sex Factors; Strychnine; Time Factors; Zoxazolamine | 1968 |
Differences in the oxidative metabolism of drugs by liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Female; Hexobarbital; Liver; Male; Methylcholanthrene; Microsomes; Oxidation-Reduction; Oxidoreductases; Pentobarbital; Phenobarbital; Proadifen; Rats; Sex Factors; Starvation; Thyroxine; Zoxazolamine | 1969 |
Nature of the effect of caffeine on the drug-metabolizing enzymes.
Topics: 17-Hydroxycorticosteroids; Acetanilides; Amino Acids; Aminopyrine; Aniline Compounds; Animals; Caffeine; Cytochromes; Dactinomycin; Drug Antagonism; Enzyme Induction; Female; Humans; Male; Methylation; Microsomes, Liver; Oxidoreductases; Phenobarbital; Pregnanes; Pyridones; Rats; Stimulation, Chemical; Time Factors; Zoxazolamine | 1969 |
Substrate-induced spectral change of liver microsomes in phenobarbital and methylcholanthrene-treated male and female rats.
Topics: Aminopyrine; Aniline Compounds; Animals; Chemical Phenomena; Chemistry; Female; Hexobarbital; Male; Meperidine; Methylcholanthrene; Microsomes, Liver; Organ Size; Oxidation-Reduction; Phenobarbital; Proteins; Rats; Spectrophotometry; Spectrum Analysis; Zoxazolamine | 1970 |
Hepatic drug metabolism after phenobarbital or 3-methylcholanthrene pretreatment of rats bearing a pituitary tumor.
Topics: Aminopyrine; Animals; Benzopyrenes; Hexobarbital; Liver; Male; Methylcholanthrene; Phenobarbital; Pituitary Neoplasms; Rats; Zoxazolamine | 1968 |
Metabolism of hexobarbital and zoxazolamine by placentae and fetal liver supernatant fraction and response to phenobarbital and chlordane treatment.
Topics: Age Factors; Animals; Chlordan; Female; Fetus; Hexobarbital; Liver; Phenobarbital; Placenta; Pregnancy; Rabbits; Zoxazolamine | 1968 |
Screening methods for measuring liver microsomal enzyme induction by drugs.
Topics: Animals; Carbon Isotopes; Enzyme Induction; Liver; Male; Microsomes; Paralysis; Phenobarbital; Rats; Sleep; Time Factors; Zoxazolamine | 1969 |
Barbiturate mortality in hypothyroid and hyperthyroid rats.
Topics: Amobarbital; Animals; Barbiturates; Basal Metabolism; Body Temperature; Body Weight; Hexobarbital; Hyperthyroidism; Hypothyroidism; Male; Pentobarbital; Phenobarbital; Rats; Thiopental; Thyroidectomy; Triiodothyronine; Zoxazolamine | 1969 |
Factors affecting the rate of disappearance of amphetamine in rats.
Topics: Age Factors; Animals; Dextroamphetamine; Estradiol; Female; Hexobarbital; Liver; Male; Methylcholanthrene; Microsomes; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Rats; Sex Factors; Time Factors; Zoxazolamine | 1969 |
Time course differences in the metabolism of drugs by hepatic microsomes from rats, rabbits and mice.
Topics: Aminopyrine; Animals; Benzoates; Benzopyrenes; Codeine; Hexobarbital; In Vitro Techniques; Liver; Mice; Microsomes; Phenobarbital; Rabbits; Rats; Species Specificity; Sulfonamides; Time; Zoxazolamine | 1966 |
Effect of pretreatment of rabbits with phenobarbital or 3-methylcholanthrene on the distribution of drug-metabolizing enzyme activity in subfractions of hepatic microsomes.
Topics: Aminopyrine; Amphetamine; Animals; Benzopyrenes; Codeine; Hexobarbital; Liver; Male; Methylcholanthrene; Microscopy, Electron; Microsomes; Mixed Function Oxygenases; Phenobarbital; Pigments, Biological; Rabbits; Zoxazolamine | 1967 |
Pharmacological properties of the isopropyl ester of o-sulfamoyl-benzoic acid.
Topics: Animals; Behavior, Animal; Benzoates; Carbamates; Carisoprodol; Chlordiazepoxide; Chlormezanone; Chlorzoxazone; Dogs; Drug Antagonism; Electroshock; Male; Mephenesin; Meprobamate; Methocarbamol; Mice; Muscles; Pentobarbital; Phenethylamines; Phenobarbital; Phenytoin; Rats; Reflex; Seizures; Sleep; Strychnine; Trimethadione; Zoxazolamine | 1967 |
The cytochromes P-450 are not involved in the modulation of the N-methyl-D-aspartate response by sigma ligands in the rat CA3 dorsal hippocampus.
Topics: Animals; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Electrophysiology; Guanidines; Hippocampus; Iontophoresis; Ligands; Male; N-Methylaspartate; Neurons; Paralysis; Phenobarbital; Proadifen; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, sigma; Zoxazolamine | 1993 |
Subchronic toxicity studies of sucrose acetate isobutyrate (SAIB) in the rat and dog.
Topics: Alkaline Phosphatase; Animal Feed; Animals; Ascorbic Acid; Biomarkers; Body Weight; Carboxylesterase; Carboxylic Ester Hydrolases; Dogs; Enzyme Induction; Female; Food Additives; Liver; Male; Microsomes, Liver; Organ Size; Phenobarbital; Rats; Rats, Sprague-Dawley; Species Specificity; Sucrose; Sulfobromophthalein; Zoxazolamine | 1998 |
The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism.
Topics: Alanine Transaminase; Animals; Aryl Hydrocarbon Hydroxylases; Cell Line; Cocaine; Coxsackie and Adenovirus Receptor-Like Membrane Protein; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Enzyme Induction; Female; Gene Expression Regulation, Enzymologic; Gene Targeting; Humans; Liver; Male; Mice; Pharmaceutical Preparations; Phenobarbital; Pyridines; Receptors, Virus; Steroid Hydroxylases; Xenobiotics; Zoxazolamine | 2000 |
Inhibition of pentobarbital and meprobamate metabolism by some 'inducers' of drug-metabolizing enzymes.
Topics: Aminopyrine; Chlorobium; Chlorpromazine; Cyclizine; Glutethimide; Meprobamate; Muscle Relaxants, Central; Nikethamide; Pentobarbital; Phenobarbital; Phenylbutazone; Tranquilizing Agents; Zoxazolamine | 1962 |
INDUCED SYNTHESIS OF OXIDATIVE ENZYMES IN LIVER MICROSOMES BY POLYCYCLIC HYDROCARBONS AND DRUGS.
Topics: Aminopyrine; Androgens; Benzopyrenes; Carbohydrate Metabolism; Carcinoma, Hepatocellular; Ethionine; Liver; Liver Neoplasms; Methionine; Methylcholanthrene; Microsomes; Microsomes, Liver; Orphenadrine; Pharmacology; Phenobarbital; Phenylbutazone; Polycyclic Compounds; Rats; Research; Zoxazolamine | 1963 |
FACTORS THAT AFFECT THE STIMULATION OF THE MICROSOMAL DRUG ENZYMES INDUCED BY FOREIGN COMPOUNDS.
Topics: Acetanilides; Adrenocorticotropic Hormone; Benzopyrenes; Hexobarbital; Liver; Methylcholanthrene; Methyltestosterone; Microsomes; Nandrolone; Pharmacology; Phenobarbital; Pyrazoles; Rats; Research; Testosterone; Zoxazolamine | 1963 |
KINETICS OF DRUG METABOLISM BY HEPATIC MICROSOMES.
Topics: Acetanilides; Chlorpromazine; Hexobarbital; Kinetics; Liver; Metabolism; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Morphine; NADP; Oxidoreductases; Pharmacology; Phenobarbital; Phenylbutazone; Rats; Research; Zoxazolamine | 1964 |
ENDOCRINE MODIFICATION OF DRUG RESPONSES IN THE RAT.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Ascorbic Acid; Barbiturates; Corticosterone; Hexobarbital; Histamine; Hypophysectomy; Injections, Intraperitoneal; Meprobamate; Pentobarbital; Pharmacology; Phenobarbital; Rats; Research; Stress, Physiological; Zoxazolamine | 1965 |
DIFFERENCES IN HEPATIC DRUG METABOLISM IN VARIOUS RABBIT STRAINS BEFORE AND AFTER PRETREATMENT WITH PHENOBARBITAL.
Topics: Aminopyrine; Amphetamine; Amphetamines; Aniline Compounds; Animals; Benzoates; Benzopyrenes; Chlorpromazine; Codeine; Hexobarbital; Liver; Metabolism; Phenobarbital; Rabbits; Research; Species Specificity; Transferases; Zoxazolamine | 1965 |
APPLICATION OF DRUG METABOLISM TO DRUG TOXICITY STUDIES.
Topics: Aspirin; Blood; Chromatography; Dicumarol; Diphenhydramine; Dogs; Drug-Related Side Effects and Adverse Reactions; Glutethimide; Griseofulvin; Histamine H1 Antagonists; Liver; Meprobamate; Metabolism; Methylcholanthrene; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Piperazines; Probenecid; Rats; Research; Strychnine; Thiopental; Toxicology; Zoxazolamine | 1965 |
Transcription coactivator PRIP, the peroxisome proliferator-activated receptor (PPAR)-interacting protein, is redundant for the function of nuclear receptors PParalpha and CAR, the constitutive androstane receptor, in mouse liver.
Topics: Acetaminophen; Active Transport, Cell Nucleus; Analgesics, Non-Narcotic; Animals; Anticonvulsants; Cells, Cultured; Constitutive Androstane Receptor; Gene Expression Regulation; Gene Targeting; Hepatocytes; Intracellular Signaling Peptides and Proteins; Liver; Male; Mice; Mice, Transgenic; Muscle Relaxants, Central; Nuclear Receptor Coactivators; Organ Size; Phenobarbital; PPAR alpha; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Transcription, Genetic; Zoxazolamine | 2007 |