phenobarbital has been researched along with vinyl chloride in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (95.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bolt, HM; Bolt, W; Buchter, A; Kappus, H | 1 |
| Aronson, I; Ivanetich, KM; Katz, ID | 1 |
| Artigou, JY; Benhamou, JP; Descatoire, V; Pessayre, D; Wandscheer, JC | 1 |
| Magnusson, J; Ramel, C | 1 |
| Hällström, I; Magnusson, J; Ramel, C | 1 |
| Jaeger, RJ; Moslen, MT; Reynolds, ES; Szabo, S | 1 |
| Jaeger, RJ; Moslen, MT; Murphy, SD; Reynolds, ES; Szabo, S | 2 |
| Guengerich, FP; Watanabe, PG | 1 |
| Arrhenius, E; Hultmark, D; Johansson, L; Sundh, K | 2 |
| Crawford, WM; Guengerich, FP; Watanabe, PG | 1 |
| Gehring, PJ; Pegg, DG; Watanabe, PG; Zempel, JA | 1 |
| Jaeger, RJ; Murphy, SD; Reynolds, ES | 1 |
| Drew, RT; Gupta, BN; Harper, C; Talley, FA | 1 |
| Chmielnicka, J; Jedrychowski, RA; Sokal, JA | 1 |
| Dramiński, W; Klimczak, J; Tarkowski, S; Wisniewska-Knypl, JM; Wróblewska, K | 1 |
| Guengerich, FP | 1 |
| Bogdanikowa, B; Dajniak, A; Klimczak, J; Sokal, JA; Wisniewska-Knypl, JM | 1 |
| Baker, MT; Ronnenberg, WC | 1 |
20 other study(ies) available for phenobarbital and vinyl chloride
| Article | Year |
|---|---|
Liver microsomal uptake of (14C)vinyl chloride and transformation to protein alkylating metabolites in vitro.
Topics: Alkylation; Animals; Biotransformation; Epoxide Hydrolases; Glutathione; In Vitro Techniques; Male; Membranes; Microsomes, Liver; NADP; Phenobarbital; Protein Binding; Proteins; Rats; Time Factors; Vinyl Chloride; Vinyl Compounds | 1976 |
The interaction of vinyl chloride with rat hepatic microsomal cytochrome P-450 in vitro.
Topics: Animals; Binding Sites; Carbon Monoxide; Cytochrome P-450 Enzyme System; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Phenobarbital; Protein Binding; Rats; Spectrophotometry; Vinyl Chloride; Vinyl Compounds | 1977 |
Formation and inactivation of a chemically reactive metabolite of vinyl chloride.
Topics: Animals; Cysteine; Cytochrome P-450 Enzyme System; DDT; Epoxide Hydrolases; Epoxy Compounds; Glutathione; Hydrocarbons, Chlorinated; Male; Microsomes, Liver; NADP; Phenobarbital; Proadifen; Protein Binding; Rats; Vinyl Chloride; Vinyl Compounds | 1979 |
Mutagenic effects of vinyl chloride on Drosophila melanogaster with and without pretreatment with sodium phenobarbiturate.
Topics: Animals; Drosophila melanogaster; Drug Therapy, Combination; Genes, Lethal; Genes, Recessive; Genetic Linkage; Genetic Techniques; Male; Mutagens; Phenobarbital; Sex Chromosomes; Vinyl Chloride; Vinyl Compounds | 1978 |
Studies on metabolic activation of vinyl chloride in Drosophila melanogaster after pretreatment with phenobarbital and polychlorinated biphenyls.
Topics: Animals; Biotransformation; Drosophila melanogaster; Enzyme Induction; Female; Male; Phenobarbital; Polychlorinated Biphenyls; Sex Factors; Species Specificity; Vinyl Chloride; Vinyl Compounds | 1979 |
Vinyl chloride-induced deactivation of cytochrome P-450 and other components of the liver mixed function oxidase system: an in vivo study.
Topics: Alanine Transaminase; Aminopyrine N-Demethylase; Animals; Aroclors; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Enzyme Activation; Ethylmorphine-N-Demethylase; Glucose-6-Phosphatase; Glutathione; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Organ Size; Oxidoreductases; Phenobarbital; Rats; Vinyl Chloride; Vinyl Compounds; Zoxazolamine | 1975 |
Hepatotoxicity of vinyl chloride and 1,1-dichloroethylene. Role of mixed function oxidase system.
Topics: Animals; Aroclors; Carcinogens; Cell Membrane; Cytochrome P-450 Enzyme System; Dichloroethylenes; Endoplasmic Reticulum; Enzyme Induction; Glutathione; Hexachlorobenzene; Hydrocarbons, Chlorinated; Liver; Liver Neoplasms; Male; Methylcholanthrene; Mitochondria, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Phenobarbital; Pregnenolone Carbonitrile; Rats; Spironolactone; Vinyl Chloride; Vinyl Compounds | 1975 |
Chemical modification of acute hepatotoxicity of vinyl chloride monomer in rats.
Topics: Animals; Aroclors; Chemical and Drug Induced Liver Injury; Disulfiram; Ethanol; Male; Maleates; Phenobarbital; Polychlorinated Biphenyls; Proadifen; Rats; Vinyl Chloride; Vinyl Compounds | 1977 |
Metabolism of [14C]- and [36C]-labeled vinyl chloride in vivo and in vitro.
Topics: Animals; Cytochrome P-450 Enzyme System; DNA; Epoxide Hydrolases; In Vitro Techniques; Male; Mitochondria, Liver; Phenobarbital; Rats; RNA; Time Factors; Vinyl Chloride; Vinyl Compounds | 1979 |
Ethanol inhibition of vinyl chloride metabolism in isolated rat hepatocytes.
Topics: Animals; Anisoles; Depression, Chemical; Ethanol; In Vitro Techniques; Liver; Male; Microsomes, Liver; Phenobarbital; Rats; Vinyl Chloride; Vinyl Compounds | 1979 |
Dichloro-p-nitroanisole O-demethylase--II. Evidence for separate ethanol inhibited and phenobarbital-inducible enzymes.
Topics: Animals; Enzyme Induction; Ethanol; Female; In Vitro Techniques; Male; Microsomes, Liver; Nitroanisole O-Demethylase; Oxidoreductases; Phenobarbital; Rats; Sex Factors; Vinyl Chloride | 1979 |
Activation of vinyl chloride to covalently bound metabolites: roles of 2-chloroethylene oxide and 2-chloroacetaldehyde.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Animals; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Ethylene Oxide; Kinetics; Male; Microsomes, Liver; Phenobarbital; Rats; Vinyl Chloride; Vinyl Compounds | 1979 |
Hepatic macromolecular binding following exposure to vinyl chloride.
Topics: Animals; Liver; Male; Phenobarbital; Protein Binding; Rats; Vinyl Chloride; Vinyl Compounds | 1978 |
Acute liver injury by vinyl chloride: involvement of endoplasmic reticulum in phenobarbital-pretreated rats.
Topics: Animals; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum; Environmental Exposure; Liver; Male; Necrosis; Phenobarbital; Rats; Vacuoles; Vinyl Chloride; Vinyl Compounds | 1975 |
Effects of vinyl chloride exposures to rats pretreated with phenobarbital.
Topics: Animals; Benzphetamine; Body Weight; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Environmental Exposure; Liver; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Organ Size; Phenobarbital; Rats; Vinyl Chloride; Vinyl Compounds | 1975 |
Comparison of the impact of continuous and intermittent exposure to vinyl chloride, including phenobarbital effect.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Body Weight; Environmental Exposure; Glutathione Transferase; L-Iditol 2-Dehydrogenase; L-Lactate Dehydrogenase; Liver; Male; Microsomes, Liver; Organ Size; Phenobarbital; Rats; Thioglycolates; Time Factors; Vinyl Chloride; Vinyl Compounds | 1985 |
Urinary excretion of thiodiglycollic acid and hepatic content of free thiols in rats at different levels of exposure to vinyl chloride.
Topics: Alcohol Oxidoreductases; Animals; Biotransformation; Cobalt; Glutathione Reductase; Liver; Male; Oxygenases; Phenobarbital; Rats; Sulfhydryl Compounds; Thioglycolates; Vinyl Chloride; Vinyl Compounds | 1980 |
Metabolism of vinyl halides: in vitro studies on roles of potential activated metabolites.
Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Biotransformation; Carbon Radioisotopes; Epoxide Hydrolases; Kinetics; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Vinyl Chloride; Vinyl Compounds | 1981 |
Protective effect of methionine against vinyl chloride-mediated depression of non-protein sulphydryls and cytochrome p-450.
Topics: Animals; Cytochrome P-450 Enzyme System; Liver; Male; Methionine; Phenobarbital; Rats; Sulfhydryl Compounds; Vinyl Chloride; Vinyl Compounds | 1981 |
Contrasting effects of 1,1,1-trichloroethane on [14C]vinyl chloride metabolism and activation in hepatic microsomes from phenobarbital- and isoniazid-treated rats.
Topics: Animals; Binding Sites; Biotransformation; Catalase; Cytochrome P-450 Enzyme System; DNA; Drug Interactions; Isoenzymes; Isoniazid; Male; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Rats, Sprague-Dawley; Trichloroethanes; Vinyl Chloride | 1993 |