phenobarbital has been researched along with valproate sodium in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 10 (62.50) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Biziere, K; Brochard, J; Brodin, R; Chambon, JP; Hallot, A; Merlier, J | 1 |
| Bastide, P; Coudert, P; Couquelet, J; Gardette, D; Moreau, S; Rubat, C; Tronche, P; Vallee-Goyet, D | 1 |
| Kohn, H; Morieux, P; Stables, JP | 1 |
| Jain, NK; Kashaw, SK; Kashaw, V; Mishra, P; Stables, JP | 1 |
| Cotten, SW; Eyers, C; Gaskell, SJ; Kohn, H; Liu, R; Morieux, P; Park, KD; Reamtong, O; Salomé, C; Stables, JP | 1 |
| DeMarco, E; Kohn, H; Morieux, P; Park, KD; Salomé, C; Salomé-Grosjean, E; Stables, JP; Swendiman, R | 1 |
| Ahsan, W; Siddiqui, N | 1 |
| Kohn, H; Salomé, C; Salomé-Grosjean, E; Stables, JP | 1 |
| He, X; Hu, X; Pan, Y; Qiu, G; Wu, W; Wu, Z; Xiao, Y; Yang, J; Zhang, T; Zhong, M | 1 |
| Deng, XQ; Quan, LN; Quan, ZS; Song, MX; Wei, CX | 1 |
| De Ryck, M; Kaminski, R; King, AM; Kohn, H; Salomé, C; Salomé-Grosjean, E; Stables, JP; Valade, A | 1 |
| De Ryck, M; Kaminski, R; King, AM; Kohn, H; Stables, JP; Valade, A | 1 |
| Guo, H; He, X; Hu, X; Qiu, G; Wu, Z; Xiao, Y; Yang, J; Zhang, T; Zhong, M | 1 |
| Baruah, PK; De Ryck, M; Dinsmore, J; Kaminski, R; King, AM; Kohn, H; Provins, L; Salomé, C | 1 |
| Chońska, J; Dawidowski, M; Mika, W; Turło, J | 1 |
| Akhtar, MJ; Bhatia, R; Grover, G; Nath, R | 1 |
1 review(s) available for phenobarbital and valproate sodium
| Article | Year |
|---|---|
Synthetic and therapeutic perspectives of nitrogen containing heterocycles as anti-convulsants.
Topics: Animals; Anticonvulsants; Heterocyclic Compounds; Humans; Molecular Structure; Seizures; Structure-Activity Relationship | 2020 |
15 other study(ies) available for phenobarbital and valproate sodium
| Article | Year |
|---|---|
Synthesis and activity of 6-aryl-3-(hydroxypolymethyleneamino)pyridazines in animal models of epilepsy.
Topics: Animals; Anticonvulsants; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Female; Hypnotics and Sedatives; Kindling, Neurologic; Male; Mice; Motor Skills; Papio; Pentylenetetrazole; Photic Stimulation; Pyridazines; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship | 1986 |
Synthesis and anticonvulsant properties of new benzylpyridazine derivatives.
Topics: Animals; Anticonvulsants; Lamotrigine; Male; Mice; Molecular Conformation; Pyridazines; Structure-Activity Relationship; Triazines | 1994 |
Synthesis and anticonvulsant activities of N-benzyl (2R)-2-acetamido-3-oxysubstituted propionamide derivatives.
Topics: Acetamides; Animals; Anticonvulsants; Binding Sites; Lacosamide; Male; Mice; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship | 2008 |
Synthesis, anticonvulsant and CNS depressant activity of some new bioactive 1-(4-substituted-phenyl)-3-(4-oxo-2-phenyl/ethyl-4H-quinazolin-3-yl)-urea.
Topics: Animals; Anticonvulsants; Behavior, Animal; Central Nervous System Depressants; Male; Mice; Molecular Structure; Pentylenetetrazole; Quinazolinones; Rats; Rats, Sprague-Dawley; Rats, Wistar; Seizures; Structure-Activity Relationship; Urea | 2009 |
Lacosamide isothiocyanate-based agents: novel agents to target and identify lacosamide receptors.
Topics: Acetamides; Animals; Anticonvulsants; Brain; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Isothiocyanates; Lacosamide; Male; Mice; Mice, Inbred ICR; Nerve Tissue Proteins; Proteome; Seizures; Serine; Stereoisomerism; Structure-Activity Relationship | 2009 |
Synthesis and anticonvulsant activities of (R)-N-(4'-substituted)benzyl 2-acetamido-3-methoxypropionamides.
Topics: Acetamides; Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Electroshock; Hippocampus; Kindling, Neurologic; Male; Mice; Molecular Structure; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Serine; Structure-Activity Relationship | 2010 |
Triazole incorporated thiazoles as a new class of anticonvulsants: design, synthesis and in vivo screening.
Topics: Animals; Anticonvulsants; Drug Design; Electroconvulsive Therapy; Lethal Dose 50; Mice; Triazoles | 2010 |
Merging the structural motifs of functionalized amino acids and alpha-aminoamides: compounds with significant anticonvulsant activities.
Topics: Acetamides; Alanine; Amides; Amino Acids; Animals; Anticonvulsants; Benzylamines; Drug Evaluation, Preclinical; Lacosamide; Mice; Pain; Rats; Seizures; Structure-Activity Relationship; Treatment Outcome | 2010 |
Synthesis and anticonvulsant activity of N-3-arylamide substituted 5,5-cyclopropanespirohydantoin derivatives.
Topics: Amides; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Hydantoins; Mice; Molecular Structure; Seizures; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship | 2010 |
Synthesis and anticonvulsant activity of 7-phenyl-6,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-ones and their derivatives.
Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Bicuculline; Electroshock; Isoniazid; Mice; Pentylenetetrazole; Pyrimidinones; Seizures; Semicarbazides; Structure-Activity Relationship; Triazoles | 2011 |
Primary amino acid derivatives: substitution of the 4'-N'-benzylamide site in (R)-N'-benzyl 2-amino-3-methylbutanamide, (R)-N'-benzyl 2-amino-3,3-dimethylbutanamide, and (R)-N'-benzyl 2-amino-3-methoxypropionamide provides potent anticonvulsants with pain
Topics: Amino Acids; Analgesics; Animals; Anticonvulsants; Butyrates; Male; Mice; Neuralgia; Pain Measurement; Propionates; Rats; Rats, Sprague-Dawley; Seizures; Stereoisomerism; Structure-Activity Relationship | 2011 |
Defining the structural parameters that confer anticonvulsant activity by the site-by-site modification of (R)-N'-benzyl 2-amino-3-methylbutanamide.
Topics: Aminobutyrates; Animals; Anticonvulsants; Male; Mice; Rats; Rats, Sprague-Dawley; Seizures; Solubility; Stereoisomerism; Structure-Activity Relationship | 2011 |
Synthesis and anticonvulsant activity of 1-(8-(benzyloxy)quinolin-2-yl)-6-substituted-4,6-diazaspiro[2,4]heptane-5,7-diones.
Topics: Animals; Anticonvulsants; Biological Assay; Electroshock; Heptanes; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Molecular Structure; Quinolines; Seizures; Spiro Compounds; Structure-Activity Relationship; Toxicity Tests | 2012 |
Synthesis, anticonvulsant activity, and neuropathic pain-attenuating activity of N-benzyl 2-amino-2-(hetero)aromatic acetamides.
Topics: Acetamides; Amino Acids; Animals; Anticonvulsants; Disease Models, Animal; Drug Evaluation, Preclinical; Male; Mice; Mice, Inbred Strains; Molecular Structure; Neuralgia; Seizures; Structure-Activity Relationship | 2012 |
Novel fluorinated pyrrolo[1,2-a]pyrazine-2,6-dione derivatives: synthesis and anticonvulsant evaluation in animal models of epilepsy.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Epilepsy; Halogenation; Hydrocarbons, Fluorinated; Male; Mice; Molecular Structure; Pentylenetetrazole; Pilocarpine; Pyrazines; Pyrroles; Rats; Rats, Sprague-Dawley; Seizures; Structure-Activity Relationship | 2014 |