phenobarbital has been researched along with urea in 83 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 72 (86.75) | 18.7374 |
| 1990's | 4 (4.82) | 18.2507 |
| 2000's | 5 (6.02) | 29.6817 |
| 2010's | 1 (1.20) | 24.3611 |
| 2020's | 1 (1.20) | 2.80 |
| Authors | Studies |
|---|---|
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Hać, E; Kaliszan, R | 1 |
| Richens, A | 1 |
| Barthels, M; Blume, U; Külpmann, WR; Oellerich, M; Schmidt, E | 1 |
| Egli, M | 1 |
| Berg, S; Pöhlmann, K; Rüdell, E | 1 |
| Brunner, G; Harstick, K; Holloway, CJ; Külpmann, WR; Petry, K | 1 |
| Arrhenius, E; Beije, B; Jenssen, D; Zetterqvist, MA | 1 |
| Anderson, G; Rassam, JW | 1 |
| Georgiev, VP; Petkova, BP | 1 |
| Rising, TJ | 1 |
| Cohn, WM; Matthay, RA; Neff, TA; Sutton, FD; Weinberger, MM; Zwillich, CW | 1 |
| Araki, Y; Ueki, S; Watanabe, S | 1 |
| Fakouhi, T; Zirvi, KA | 1 |
| Hansen, S; MacLean, J; Perry, TL | 1 |
| Briggs, WA; Gibson, TP; Matusik, E; Nelson, LD | 1 |
| Latham, AN; Sweeney, GD | 1 |
| Pozdniakov, VS | 1 |
| Keller, BJ; Liang, DC; Misra, UK; Thurman, RG | 1 |
| Fischer-Nielsen, A; Hage, E; Hansen, BA; Keiding, S; Poulsen, HE | 1 |
| Danhof, M; Levy, G | 1 |
| Dekeyser, J; Huyghens, L; Maes, V; Sevens, C | 1 |
| Diwan, BA; Hu, H; Lubet, RA; Nims, RW; Rice, JM; Ward, JM | 1 |
| Benner, KE; Bennett, WM; Houghton, DC; Sasaki, AW; Schwass, DE | 1 |
| Assadi, FK; Chow-Tung, E; Fornell, L; John, E; Lau, AH | 1 |
| Tölle, R | 1 |
| Grabensee, B | 1 |
| Millichap, JG | 1 |
| Inoki, R; Otori, K; Yamamoto, I | 1 |
| Srebocan, S; Stern, P | 1 |
| Kempfle, B; Reschke, L; Schmidtmann, W | 1 |
| Mandel, HG; Riis, M | 1 |
| Hoffmeister, F | 1 |
| Gibert, C; Pocidalo, JJ; Tremolières, F; Vachon, F | 1 |
| Alexander, E | 1 |
| Hishida, S; Mizoi, Y; Tanabe, T; Ueda, M | 1 |
| el-Bassiouni, EA; Mattocks, AM | 1 |
| Latham, AN; Richens, A | 1 |
| Cantor, PA; Fisher, BS; Higley, WS; Stone, W | 1 |
| Panchenko, EN | 1 |
| Baylis, EM; Fry, DE; Marks, V; Papadopoulos, AS | 1 |
| Bush, MT; Gerber, N; Holcomb, RR | 1 |
| Abd-Elfattah, S; Daabis, NA; el-Banna, HM | 1 |
| Swinyard, EA | 1 |
| Goldstein, L; Pfeiffer, CC | 1 |
| Fukuta, T; Shimazono, Y | 1 |
| Kondo, M | 1 |
| Cavanagh, JB; Chen, FC | 1 |
| Ambre, JJ; Fischer, LJ | 1 |
| Baumann, K; Oelert, H; Sonnenberg, H | 1 |
| Huisman, JW; van Heycop ten Ham, MW; van Zijl, CH | 1 |
| Koe, BK; Weissman, A | 1 |
| Callahan, EW; Landaw, SA; Schmid, R | 1 |
| Powell, C; Raftell, M | 1 |
| Orndorff, M; Papper, S; Whang, R | 1 |
| Pavlovec, A; Petermann, ML | 1 |
| Becker, B; Krupin, T; Podos, SM | 1 |
| Gillen, HW; Pippinger, CE | 1 |
| Ljungberg, S; Paalzow, L; Ström, S | 1 |
| Paalzow, L | 1 |
| Camerman, A; Camerman, N | 1 |
| Fulco, AJ; Kim, BH; Ruettinger, RT | 1 |
| Christofides, JA; Fry, DE | 1 |
| Baltassat, P; Cahen, R; Francois, B; Louisot, P; Martin, A | 1 |
| Day, SH; Nicoll-Griffith, DA; Silva, JM | 1 |
| Akhmedzhanov, RR; Novozheeva, TP; Saratikov, AS | 1 |
| BURGERMEISTER-GUEX, G; DUCOMMUN, M; FROMMEL, E; GOLD, P; RADOUCO, C | 1 |
| FROMMEL, E; RADOUCO-THOMAS, C | 1 |
| PETERS, JJ; VONDERAHE, AR | 1 |
| SOREL, L | 1 |
| KRAUSS, S | 1 |
| BARLOW, CF; GOLDBERG, MA; ROTH, LJ | 1 |
| CORRIOL, J; FONDARAI, J; JOANNY, P | 1 |
| CHUBB, FL; HAJDU, A; KOMLOSSY, J; LEE, CF; MCCOLL, JD | 1 |
| CASOLA, L; GIUDITTA, A; ROCCA, E | 1 |
| MULLAN, D; PLATTS, M; RIDGWAY, B | 1 |
| GOLD, P; RADOUCO-THOMAS, C; RADOUCO-THOMAS, S | 1 |
| Li, WC; Ralphs, KL; Slack, JM; Tosh, D | 1 |
| Bracht, A; Ishii-Iwamoto, EL; Maioli, MA; Mingatto, FE | 1 |
| Gotohda, T; Hara, K; Ishigami, A; Kageura, M; Kashiwagi, M; Kubo, S; Lu, W; Matsusue, A; Nisimura, A; Sugimura, T; Tokunaga, I | 1 |
| Abe, M; Inoue, A; Katsuda, T; Kawamata, M; Ochiya, T; Yamaguchi, T | 1 |
4 review(s) available for phenobarbital and urea
| Article | Year |
|---|---|
Interactions with antiepileptic drugs.
Topics: Acetaminophen; Acetazolamide; Anti-Anxiety Agents; Anticoagulants; Anticonvulsants; Carbamazepine; Diazepam; Drug Interactions; Furosemide; Gonadal Steroid Hormones; Griseofulvin; Humans; Phenobarbital; Phenytoin; Primidone; Thiazines; Urea; Valproic Acid; Vitamin D | 1977 |
Relation of laboratory evaluation to clinical effectiveness of antiepileptic drugs.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzazepines; Clinical Trials as Topic; Drug Tolerance; Electroencephalography; Electroshock; Epilepsy; Ethosuximide; Humans; Pentylenetetrazole; Phenobarbital; Phenytoin; Primidone; Seizures; Trimethadione; Urea | 1969 |
Laboratory evaluation of antiepileptic drugs. Review of laboratory methods.
Topics: Animals; Anticonvulsants; Biological Assay; Brain Injuries; Diagnosis; Electroconvulsive Therapy; Electroshock; Humans; Methionine Sulfoximine; Methods; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Seizures; Strychnine; Thiosemicarbazones; Trimethadione; Urea | 1969 |
[Drug therapy of epilepsy].
Topics: Epilepsy; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Trimethadione; Urea | 1967 |
2 trial(s) available for phenobarbital and urea
| Article | Year |
|---|---|
Relation of laboratory evaluation to clinical effectiveness of antiepileptic drugs.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzazepines; Clinical Trials as Topic; Drug Tolerance; Electroencephalography; Electroshock; Epilepsy; Ethosuximide; Humans; Pentylenetetrazole; Phenobarbital; Phenytoin; Primidone; Seizures; Trimethadione; Urea | 1969 |
Quantitative EEG analysis of single-dose effect relationships in normal volunteers of Pacinox (capuride), a new antianxiety drug.
Topics: Administration, Oral; Adult; Anxiety; Blood Pressure; Brain; Chlordiazepoxide; Clinical Trials as Topic; Electroencephalography; Heart; Humans; Hypnotics and Sedatives; Male; Meprobamate; Middle Aged; Phenobarbital; Placebos; Pulse; Tranquilizing Agents; Urea | 1971 |
78 other study(ies) available for phenobarbital and urea
| Article | Year |
|---|---|
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Studies on the polymorphism of carbromal.
Topics: Animals; Chloral Hydrate; Chlorpromazine; Crystallization; Drug Synergism; Ethyl Ethers; Hot Temperature; Mice; Phenobarbital; Sleep; Spectrophotometry, Infrared; Urea | 1976 |
[In vitro evaluation of adsorbents used in haemoperfusion (author's transl)].
Topics: Adsorption; Blood Coagulation Disorders; Charcoal; Diazepam; Hemoperfusion; Humans; Inactivation, Metabolic; Phenobarbital; Urea | 1978 |
[Drug interactions in antiepileptic combination therapy].
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Enzyme Induction; Humans; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Thiazines; Time Factors; Urea; Valproic Acid | 1979 |
[The reaction of lung mast cells to acute barbiturate and bromureide poisoning (author's transl)].
Topics: Animals; Barbital; Barbiturates; Bromides; Cytoplasmic Granules; Female; Guinea Pigs; Lung; Mast Cells; Phenobarbital; Urea | 1978 |
The removal of hypnotic drugs from human serum. A comparative investigation of the adsorptive properties of native and agarose-encapsulated resins and charcoal.
Topics: Adsorption; Biocompatible Materials; Capsules; Charcoal; Glutethimide; Hemoperfusion; Humans; Hypnotics and Sedatives; Ion Exchange Resins; Mathematics; Methaqualone; Phenobarbital; Polysaccharides; Sepharose; Urea | 1979 |
Isolated liver perfusion--a tool in mutagenicity testing for the evaluation of carcinogens.
Topics: Animals; Aroclors; Cell Line; Cricetinae; Cytochrome P-450 Enzyme System; Gluconeogenesis; Lactates; Liver; Lung; Male; Methylcholanthrene; Microsomes, Liver; Mutation; Perfusion; Phenobarbital; Polychlorinated Biphenyls; Protein Biosynthesis; Rats; Urea | 1979 |
Letter: Exfoliative dermatitis during treatment with pheneturide.
Topics: Adult; Anticonvulsants; Dermatitis, Exfoliative; Epilepsy; Humans; Male; Phenobarbital; Phenylbutyrates; Phenytoin; Prednisolone; Urea | 1975 |
Effect of p-chlorophenylalanine on the central nervous excitability threshold and on the activity of some central depressants.
Topics: Animals; Central Nervous System; Depression, Chemical; Fenclonine; Hypnotics and Sedatives; Injections, Intraperitoneal; Injections, Intravenous; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenylacetates; Picrotoxin; Seizures; Strychnine; Time Factors; Toluene; Urea | 1975 |
Effects of hepatic microsomal enzyme inducers of the endogenous substrates vitamin D3 and folate in rat.
Topics: Animals; Anticonvulsants; Body Weight; Cholecalciferol; Enzyme Induction; Folic Acid; Formiminoglutamic Acid; Liver; Male; Microsomes, Liver; Organ Size; Phenobarbital; Phenylbutyrates; Rats; Urea | 1979 |
Theophylline-induced seizures in adults. Correlation with serum concentrations.
Topics: Adult; Aged; Creatinine; Diazepam; Dose-Response Relationship, Drug; Female; Humans; Hydrogen-Ion Concentration; Injections, Intravenous; Kidney; Liver; Male; Middle Aged; Nitrogen; Phenobarbital; Phenytoin; Seizures; Theophylline; Urea | 1975 |
Changes in sensitivity of mice to anticonvulsant drugs following bilateral olfactory bulb ablations.
Topics: Acetazolamide; Animals; Anticonvulsants; Chlordiazepoxide; Diazepam; Dose-Response Relationship, Drug; Electroshock; Male; Mice; Nitrazepam; Olfactory Bulb; Phenobarbital; Phenylacetates; Phenytoin; Trimethadione; Urea; Valproic Acid | 1977 |
Synthesis and neuropharmacology of cyclobutanecarbonylureas.
Topics: Animals; Central Nervous System Depressants; Female; Male; Mice; Oxotremorine; Pentylenetetrazole; Phenobarbital; Strychnine; Urea | 1979 |
Cerebrospinal fluid and plasma glutamine elevation by anticonvulsant drugs: a potential diagnostic and therapeutic trap.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Arginine; Child; Child, Preschool; Citrulline; Epilepsy; False Positive Reactions; Female; Glutamine; Humans; Infant; Male; Middle Aged; Ornithine; Phenobarbital; Primidone; Urea | 1976 |
Artificial kidneys and clearance calculations.
Topics: Blood Flow Velocity; Humans; Kidneys, Artificial; Mathematics; Metabolic Clearance Rate; Pharmaceutical Preparations; Phenobarbital; Plasma; Procainamide; Quinidine; Renal Dialysis; Urea | 1976 |
Binding of anticonvulsant drugs to cytochrome P-450: correlation with evidence of induction of hepatic microsomal enzymes.
Topics: Animals; Anticonvulsants; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Glucaric Acid; Hexobarbital; In Vitro Techniques; Kinetics; Male; Mephenytoin; Microsomes, Liver; Phenobarbital; Phenylbutyrates; Phenytoin; Rats; Receptors, Drug; Urea | 1976 |
[An analysis of 22 years' experience with the medicinal treatment of epilepsy].
Topics: Adult; Anticonvulsants; Bromides; Caffeine; Codeine; Drug Therapy, Combination; Epilepsy; Female; History, 20th Century; Humans; Influenza, Human; Male; Middle Aged; Papaverine; Phenobarbital; Phytotherapy; Plants, Medicinal; Sodium; Tranquilizing Agents; Urea; USSR | 1975 |
Oxygen tension is a major determinant of hepatotoxicity due to 2-ethylhexanol in isolated tissue cylinders from periportal and pericentral regions of the liver lobule from phenobarbital-treated rats.
Topics: Animals; Cell Survival; Culture Techniques; Female; Hexanols; L-Lactate Dehydrogenase; Liver; Oxygen; Phenobarbital; Rats; Rats, Inbred Strains; Urea | 1991 |
CCl4 cirrhosis in rats: irreversible histological changes and differentiated functional impairment.
Topics: Animals; Antipyrine; Carbon Tetrachloride; Galactose; Liver; Liver Cirrhosis, Experimental; Male; Phenobarbital; Rats; Rats, Inbred Strains; Urea | 1991 |
Kinetics of drug action in disease states. V. Acute effect of urea infusion on phenobarbital concentrations in rats at onset of loss of righting reflex.
Topics: Animals; Barbiturates; Blood Urea Nitrogen; Brain; Female; Kinetics; Phenobarbital; Postural Balance; Rats; Rats, Inbred Lew; Reflex; Thiopental; Urea; Uremia | 1985 |
Acute and chronic intoxication with carbromal preparations.
Topics: Acute Disease; Bromides; Chlorides; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Chronic Disease; Gastric Juice; Humans; Phenobarbital; Urea | 1985 |
Tumor promoting activities of ethylphenylacetylurea and diethylacetylurea, the ring hydrolysis products of barbiturate tumor promoters phenobarbital and barbital, in rat liver and kidney initiated by N-nitrosodiethylamine.
Topics: Animals; Barbital; Body Weight; Carcinogens; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Enzyme Induction; Kidney Neoplasms; Liver Neoplasms; Phenobarbital; Rats; Rats, Inbred F344; Thyroid Neoplasms; Urea | 1989 |
Effect of phenobarbital and cimetidine on experimental cyclosporine nephrotoxicity: preliminary observations.
Topics: Animals; Cimetidine; Creatinine; Cyclosporins; Cytochrome P-450 Enzyme System; Drug Interactions; Inulin; Kidney Diseases; Kidney Tubules; Liver; Phenobarbital; Rats; Rats, Inbred F344; Urea | 1986 |
Effect of ultrafiltration on peritoneal dialysis drug clearances.
Topics: Animals; Creatinine; Peritoneal Dialysis; Pharmaceutical Preparations; Phenobarbital; Rabbits; Theophylline; Tobramycin; Ultrafiltration; Urea | 1985 |
[Unexpected complications by anticholinergics contained in hypnotics and analgesics].
Topics: Adult; Analgesics; Benactyzine; Codeine; Diphenhydramine; Drug Combinations; Female; Humans; Hypnotics and Sedatives; Male; Methaqualone; Parasympatholytics; Phenacetin; Phenobarbital; Psychoses, Substance-Induced; Salicylamides; Urea | 1974 |
[Therapy of severe bromcarbamide poisoning].
Topics: Blood Pressure Determination; Diuresis; Electroencephalography; Furosemide; Gastric Lavage; Germany, West; Humans; Phenobarbital; Plasma Substitutes; Poisoning; Renal Dialysis; Suicide; Urea; Water-Electrolyte Balance | 1974 |
Pharmacological studies on antagonists against nicotine-induced convulsions and death.
Topics: Animals; Anticonvulsants; Chlorpromazine; Drug Antagonism; Female; Ganglionic Blockers; Hexamethonium Compounds; Histamine H1 Antagonists; Male; Meprobamate; Mice; Nicotine; Parasympatholytics; Perphenazine; Phenobarbital; Phentolamine; Reserpine; Seizures; Sympatholytics; Thiazoles; Tolazoline; Tranquilizing Agents; Urea | 1966 |
The origin of epileptiform seizures caused by oil of Artemisia caerulescens L.
Topics: Aminobenzoates; Animals; Behavior, Animal; Cerebral Decortication; Magnoliopsida; Mephenesin; Mice; Oils; Phenobarbital; Phenylacetates; Phenytoin; Plant Extracts; Respiration; Seizures; Substance P; Urea | 1968 |
[A spray reagent combination for differential determination of methyprylon from its main metabolite methylpersedon as well as a selection of hypnotics and eukraton on thin layer chromatograms].
Topics: Barbiturates; Bemegride; Chromatography, Thin Layer; Glutethimide; Hexobarbital; Hypnotics and Sedatives; Indicators and Reagents; Methaqualone; Phenobarbital; Piperidines; Urea | 1969 |
Interference of barbiturates with pyrimidine incorporation. II. Structural specificity of the inhibition of orotate uptake in Bacillus cereus.
Topics: Amobarbital; Bacillus cereus; Barbiturates; Bemegride; Biological Transport; Carbon Isotopes; Carboxylic Acids; Central Nervous System Stimulants; Chemical Phenomena; Chemistry; Chemistry, Physical; Chlorine; Chlorpromazine; Glutethimide; Hexobarbital; Hydantoins; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; Orotic Acid; Pentobarbital; Phenobarbital; Phenytoin; Primidone; Solubility; Succinimides; Thiopental; Thymine; Trimethadione; Tromethamine; Uracil; Urea | 1970 |
Anticonvulsant drugs in idiopathic epilepsy.
Topics: Acetazolamide; Anticonvulsants; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Hydantoins; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Substance Withdrawal Syndrome; Succinimides; Urea | 1970 |
[Electroencephalogram and behavior of rabbits in physiological and drug-induced sleep. 3. Influence of hypnotics on sleeping behavior of rabbits; discussion and summary].
Topics: Animals; Barbiturates; Behavior, Animal; Circadian Rhythm; Cyclohexanes; Diazepam; Electroencephalography; Hypnotics and Sedatives; Methaqualone; Motor Activity; Nitrazepam; Periodicity; Phenobarbital; Piperidones; Promethazine; Rabbits; Sleep; Sleep Stages; Sleep, REM; Urea | 1972 |
Effect of curarization on energy and nitrogen balances in acute tetanus treated by prolonged administration of D tubo-curarine.
Topics: Calorimetry; Diazepam; Energy Metabolism; Humans; Muscles; Nitrogen; Phenobarbital; Proteins; Spirometry; Tetanus; Tubocurarine; Urea | 1974 |
Medical management of closed head injuries.
Topics: Adolescent; Adult; Aged; Airway Obstruction; Anti-Bacterial Agents; Blood Transfusion; Cerebral Angiography; Cerebral Hemorrhage; Child; Craniocerebral Trauma; Decerebrate State; Embolism, Fat; Glucocorticoids; Humans; Hyperbaric Oxygenation; Hypothermia, Induced; Intracranial Pressure; Intubation, Intratracheal; Mannitol; Middle Aged; Monitoring, Physiologic; Neurologic Examination; Phenobarbital; Phenytoin; Plasma Substitutes; Pneumonia, Aspiration; Urea | 1972 |
Experimental studies on the detection of hypnotics using thin layer chromatography.
Topics: Animals; Barbiturates; Carbamates; Chromatography, Thin Layer; Glutethimide; Hypnotics and Sedatives; Phenobarbital; Quinazolines; Rabbits; Stomach; Urea | 1972 |
Acceleration of peritoneal dialysis with minimal N-myristyl-beta-aminopropionate.
Topics: Adsorption; Amines; Amobarbital; Animals; Barbiturates; beta-Alanine; Carbon Isotopes; Lethal Dose 50; Male; Mice; Peritoneal Dialysis; Phenobarbital; Phenytoin; Propionates; Rabbits; Salicylates; Surface-Active Agents; Urea | 1973 |
Pheneturide, a more potent liver enzyme inducer in man than phenobarbitone?
Topics: Adipates; Anticonvulsants; Enzyme Induction; Epilepsy; Female; Humans; Liver; Male; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Sugar Acids; Urea | 1973 |
Modified polycarbonate membranes for hemodialysis.
Topics: Animals; Biocompatible Materials; Blood Coagulation; Carbonates; Creatinine; Ethers; Kidneys, Artificial; Membranes, Artificial; Mice; Molecular Weight; Phenobarbital; Polymers; Rabbits; Renal Dialysis; Sucrose; Ultrafiltration; Urea; Vitamin B 12 | 1973 |
[Treatment of extrapyramidal hyperkinesis].
Topics: Adolescent; Adult; Ambulatory Care; Basal Ganglia Diseases; Benzimidazoles; Benzyl Compounds; Bromine; Caffeine; Chronic Disease; Drug Combinations; Humans; Hyperkinesis; Male; Middle Aged; Papaverine; Parasympatholytics; Phenobarbital; Powders; Urea; Valerates | 1973 |
A rapid micro-method for determining four anti-convulsant drugs by gas-liquid chromatography.
Topics: Animals; Anticonvulsants; Carbon Radioisotopes; Chromatography, Gas; Evaluation Studies as Topic; Horses; Methods; Microchemistry; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Time Factors; Urea | 1973 |
The metabolic fate of hexobarbital in the rat.
Topics: Animals; Bile; Carbon Radioisotopes; Countercurrent Distribution; Feces; Half-Life; Hexobarbital; Hydroxylation; In Vitro Techniques; Ketones; Kidney; Kinetics; Liver; Male; Perfusion; Phenobarbital; Proadifen; Rats; Spectrophotometry, Ultraviolet; Time Factors; Urea | 1974 |
Physicochemical study of drug binary systems. 1. Phenobarbital-urea system.
Topics: Chemical Phenomena; Chemistry, Physical; Crystallization; Drug Interactions; Phenobarbital; Solubility; Urea | 1974 |
Isolation and identification of hypnotics. 9. Simultaneous identification of hypnotics and alcohols.
Topics: 1-Propanol; Alcohols; Alkynes; Animals; Carbamates; Chromatography, Thin Layer; Cyclohexanes; Ethanol; Hypnotics and Sedatives; Methanol; Methaqualone; Phenobarbital; Rabbits; Urea; Valerates | 1972 |
Factors affecting neurotoxicity by p-bromophenylacetylurea in rats.
Topics: Acetylcholinesterase; Age Factors; Animals; Biotransformation; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cholinesterase Inhibitors; Esterases; Female; Hepatectomy; Liver; Male; Microsomes, Liver; Nervous System Diseases; Paralysis; Phenobarbital; Rats; Sex Factors; Time Factors; Urea | 1971 |
The effect of prednisolone and other factors on the catabolism of 5-fluorouracil in rats.
Topics: Animals; Autoradiography; Carbon Dioxide; Carbon Isotopes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chromatography, Ion Exchange; Drug Interactions; Fluorine; Fluorouracil; Male; Phenobarbital; Prednisolone; Propionates; Rats; Urea | 1971 |
Proximal tubular reabsorption of some organic acids in the rat kidney in vivo.
Topics: Absorption; Aminohippuric Acids; Animals; Cats; Kidney Tubules; Perfusion; Phenobarbital; Sulfamerazine; Sulfanilamides; Urea; Uric Acid | 1965 |
Influence of ethylphenacemide on serum levels of other anti-epileptic drugs.
Topics: Adolescent; Adult; Benzazepines; Butyrates; Chromatography, Thin Layer; Colorimetry; Drug Synergism; Humans; Male; Phenobarbital; Phenytoin; Primidone; Urea | 1970 |
m-Fluorotyrosine convulsions and mortality: relationship to catecholamine and citrate metabolism.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anticonvulsants; Atropine; Azoles; Brain; Chlordiazepoxide; Chlorpromazine; Citrates; Dihydroxyphenylalanine; Disulfiram; Drug Antagonism; Drug Synergism; Kidney; Lysergic Acid Diethylamide; Male; Methyldopa; Mice; Morphine; Nialamide; Norepinephrine; Pargyline; Phenobarbital; Phenytoin; Reserpine; Seizures; Serotonin; Strychnine; Tetrabenazine; Trimethadione; Tyrosine; Urea | 1967 |
Catabolism of heme in vivo: comparison of the simultaneous production of bilirubin and carbon monoxide.
Topics: Animals; Bile; Bilirubin; Carbon Isotopes; Carbon Monoxide; Feces; Glycine; Heme; Injections, Intravenous; Liver; Phenobarbital; Rats; Respiration; Urea | 1970 |
Immunochemical characterization of submicrosomal rat liver esterases.
Topics: Acetylesterase; Animals; Animals, Newborn; Antigens; Chloromercuribenzoates; Cholinesterases; Esterases; Fatty Acids; Female; Hot Temperature; Immunochemistry; Immunoelectrophoresis; Isoflurophate; Kidney; Male; Microsomes; Microsomes, Liver; Phenobarbital; Physostigmine; Rabbits; Rats; Testis; Urea | 1970 |
Lipid-electrolyte ("lipo-lyte") dialysis--experimental and preliminary clinical observations.
Topics: Acid-Base Equilibrium; Adult; Animals; Cottonseed Oil; Dogs; Female; Humans; Lipids; Male; Methods; Phenobarbital; Poisoning; Renal Dialysis; Secobarbital; Solubility; Time Factors; Urea; Water-Electrolyte Balance | 1970 |
Dissociation of rat liver ribosomes to active subunits by urea.
Topics: Animals; Bile Acids and Salts; Carbon Isotopes; Cell Fractionation; Centrifugation, Density Gradient; Chemical Precipitation; Chlorides; Chromatography, Gel; Liver; Macromolecular Substances; Magnesium; Male; Microsomes, Liver; Phenobarbital; Phenylalanine; Polynucleotides; Protein Biosynthesis; Rats; Ribonucleases; Ribosomes; Sulfhydryl Compounds; Ultracentrifugation; Uracil Nucleotides; Urea | 1971 |
Mechanism of intraocular pressure response after optic nerve transection.
Topics: Acetazolamide; Animals; Aqueous Humor; Atropine; Autonomic Nervous System; Denervation; Depression, Chemical; Furans; Half-Life; Hypothalamus; Intraocular Pressure; Iodine Isotopes; Iodohippuric Acid; Isosorbide Dinitrate; Male; Optic Nerve; Phenobarbital; Phentolamine; Rabbits; Stimulation, Chemical; Tonometry, Ocular; Urea; Water | 1971 |
Low specific gravity syndrome.
Topics: Adult; Anticonvulsants; Calcium; Chlorides; Chronic Disease; Creatinine; Epilepsy; Female; Humans; Intellectual Disability; Male; Mass Screening; Metabolic Clearance Rate; Middle Aged; Osmolar Concentration; Phenobarbital; Phenytoin; Potassium; Sodium; Specific Gravity; Time Factors; Urea; Urine; Vasopressins; Water-Electrolyte Balance | 1968 |
Anticonvulsant activity of ectylurea in mice.
Topics: Animals; Anticonvulsants; Electroshock; Mice; Phenobarbital; Picrotoxin; Strychnine; Urea | 1968 |
Studies of analgesic and anticonvulsant activity in mice by high-frequency electrical stimulation.
Topics: Age Factors; Analgesics; Animals; Anticonvulsants; Aspirin; Body Weight; Electric Stimulation; Electrodes; Hindlimb; Male; Methods; Mice; Pain; Pentazocine; Phenobarbital; Salicylates; Tail; Time Factors; Urea | 1969 |
Stereochemical similarities in chemically different antiepileptic drugs.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzeneacetamides; Diazepam; Molecular Conformation; Phenobarbital; Phenylacetates; Phenylbutyrates; Phenytoin; Procyclidine; Stereoisomerism; Structure-Activity Relationship; Trihexyphenidyl; Urea | 1980 |
Acylureas: a new class of barbiturate-like bacterial cytochrome P-450 inducers.
Topics: Anthraquinones; Bacillus megaterium; Barbiturates; Chemical Phenomena; Chemistry; Cytochrome P-450 Enzyme System; Enzyme Induction; Hot Temperature; Hydrolysis; Hydroxylation; Oxygenases; Phenobarbital; Solutions; Structure-Activity Relationship; Urea | 1984 |
Measurement of anticonvulsants in serum by reversed-phase ion-pair liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Urea | 1980 |
Creatinine metabolism impairment by an anticonvulsant drug, phenacemide.
Topics: Adult; Anticonvulsants; Benzeneacetamides; Carbamazepine; Creatinine; Epilepsy, Temporal Lobe; Glomerular Filtration Rate; Humans; Male; Phenobarbital; Urea | 1994 |
Induction of cytochrome-P450 in cryopreserved rat and human hepatocytes.
Topics: Animals; Blotting, Western; Cell Survival; Cells, Cultured; Cryopreservation; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Humans; Liver; Male; Organ Preservation; Phenobarbital; Rats; Rats, Sprague-Dawley; Steroid Hydroxylases; Urea | 1999 |
Efficiency of enzyme-inducing agents in rats with intrahepatic cholestasis.
Topics: 1-Naphthylisothiocyanate; Animals; Barbiturates; Benzhydryl Compounds; Bilirubin; Cholestasis, Intrahepatic; Cytochrome P-450 Enzyme System; Female; Glutathione Transferase; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Urea | 2002 |
[Peripheral action of anticonvulsants: phenobarbital, phenylethylacetylurea and diphenylhydantoine].
Topics: Anticonvulsants; Barbiturates; Hydantoins; Muscles; Phenobarbital; Urea | 1953 |
[Significance of the attack point of diphenylhydantoin, phenobarbital and the acylureas for our comprehension of the physiopathological mechanism of epilepsy].
Topics: Animals; Barbiturates; Behavior, Animal; Comprehension; Epilepsy; Humans; Hydantoins; Phenobarbital; Phenytoin; Social Behavior; Urea | 1953 |
Electroencephalographic studies, induced seizures, and their modification by phenobarbital, dilantin, and phenurone, in the salamanders, Triturus viridescens and Ambystoma tigrinum.
Topics: Ambystoma; Animals; Anticonvulsants; Barbiturates; Benzeneacetamides; Electroencephalography; Humans; Hydantoins; Notophthalmus viridescens; Phenobarbital; Phenytoin; Seizures; Urea; Urodela | 1954 |
[Experimental and clinical results of certain recent antiepileptic substances (doriden, gemonil, hibicon, milontin, mysoline and trinurid)].
Topics: Anticonvulsants; Barbiturates; Glutethimide; Humans; Phenobarbital; Primidone; Succinimides; Urea | 1957 |
Trinuride H: a new antiepileptic drug; report on a pilot clinical trial.
Topics: Anticonvulsants; Humans; Hydantoins; Phenobarbital; Urea | 1958 |
The effects of carbon dioxide on the entry and accumulation of drugs in the central nervous system.
Topics: Acetazolamide; Carbon Dioxide; Central Nervous System; Phenobarbital; Salicylates; Salicylic Acid; Urea | 1961 |
[ACTION OF VARIOUS UREIDES ON K GRADIENTS OF MAMMALIAN CEREBRAL TISSUE ELECTRICALLY STIMULATED IN VITRO].
Topics: Anticonvulsants; Barbiturates; Brain; Electrophysiological Phenomena; Electrophysiology; Guinea Pigs; Hydantoins; Hypnotics and Sedatives; In Vitro Techniques; Metabolism; Pentobarbital; Pharmacology; Phenobarbital; Phenytoin; Potassium; Research; Urea | 1963 |
SYNTHESIS AND PHARMACOLOGICAL PROPERTIES OF PHENYL-SUBSTITUTED BIURETS.
Topics: Atropine; Biuret; Chemistry, Pharmaceutical; Gastric Juice; Meprobamate; Mice; Nicotine; Pentylenetetrazole; Peptic Ulcer; Pharmacology; Phenformin; Phenobarbital; Picrotoxin; Rats; Research; Seizures; Strychnine; Toxicology; Urea | 1963 |
BARBITURATE INHIBITION OF D-ASPARTATE OXIDOREDUCTASE: MECHANISM OF ACTION AND STRUCTURAL REQUIREMENTS.
Topics: Amino Acid Oxidoreductases; Amobarbital; Animals; Aspartic Acid; Barbiturates; Chloral Hydrate; D-Aspartic Acid; Enzyme Inhibitors; Ferrocyanides; Metabolism; Mollusca; Oxidoreductases; Pentobarbital; Pharmacology; Phenobarbital; Research; Thiopental; Thiourea; Urea | 1964 |
BARBITURATE INTOXICATION.
Topics: Amobarbital; Barbiturates; Coma; Diagnosis; Electrocardiography; Hypnotics and Sedatives; Hypoxia, Brain; Kidneys, Artificial; Phenobarbital; Respiration, Artificial; Toxicology; Urea | 1965 |
[Study of the activity and toxicity of antiepileptic drugs (phenobarbital, diphenylhydantoin, phenylethylacetylurea and 5-ethylhexahydro-5-phenylpyrimidine-4,6-dione)].
Topics: Anticonvulsants; Barbiturates; Hydantoins; Phenobarbital; Phenytoin; Urea | 1954 |
Keratinocyte serum-free medium maintains long-term liver gene expression and function in cultured rat hepatocytes by preventing the loss of liver-enriched transcription factors.
Topics: Animals; Base Sequence; Blotting, Western; Cell Differentiation; Cells, Cultured; Culture Media, Conditioned; Culture Media, Serum-Free; DNA Primers; Gene Expression; Hepatocytes; Keratinocytes; Liver Glycogen; Organ Preservation Solutions; Phenobarbital; Phenotype; Rats; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Transcription Factors; Urea | 2007 |
Effects of monocrotaline on energy metabolism in the rat liver.
Topics: Alanine; Animals; Carcinogens; Cytochrome P-450 Enzyme System; Data Interpretation, Statistical; Energy Metabolism; Gluconeogenesis; Glycogen; Glycolysis; Liver; Liver Circulation; Male; Monocrotaline; Oxygen Consumption; Phenobarbital; Pyruvic Acid; Rats; Rats, Wistar; Urea | 2008 |
Genetic analysis of ryanodine receptor 1 gene and carnitine palmitoyltransferase II gene: an autopsy case of neuroleptic malignant syndrome related to vegetamin.
Topics: Adult; Amino Acid Substitution; Antipsychotic Agents; Brain; Brain Edema; Carnitine O-Palmitoyltransferase; Chlorpromazine; Creatinine; Drug Combinations; Drug Overdose; Epidermis; Exons; Forensic Genetics; Forensic Pathology; Heterozygote; Humans; Kidney; Male; Muscle, Skeletal; Myoglobinuria; Neuroleptic Malignant Syndrome; Nitrogen; Organ Size; Phenobarbital; Rhabdomyolysis; Ryanodine Receptor Calcium Release Channel; Suicide; Urea | 2009 |
Long-term maintenance of functional primary human hepatocytes using small molecules.
Topics: Amides; Cell Proliferation; Cells, Cultured; Cytochrome P-450 Enzyme System; Glycogen; Hepatocytes; Humans; Phenobarbital; Primary Cell Culture; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Rifampin; Urea | 2020 |