phenobarbital and trimethadione

phenobarbital has been researched along with trimethadione in 109 studies

Research

Studies (109)

TimeframeStudies, this research(%)All Research%
pre-199097 (88.99)18.7374
1990's7 (6.42)18.2507
2000's3 (2.75)29.6817
2010's2 (1.83)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hanson, JW; Mellman, WJ; Neiderer, B; Zackai, EH1
Gandhi, IC; Jindal, MN; Patel, VK1
Araki, Y; Ueki, S; Watanabe, S1
Hori, M; Ito, T; Shimizu, M; Yoshida, K3
Göbel, W; Löscher, W1
Fenichel, GM; McLain, LW; Montouris, GD1
Boisse, NR; Okamoto, M; Rosenberg, HC1
Banerjee, U; Yeoh, PN1
Frey, HH; Löscher, W2
Goodman, RM; Hertz, M; Katznelson, D; Katznelson, MB; Rotem, Y1
Knotts, GR; Thomas, JA1
Gardner, CR; Webster, RA2
Anderson, RC1
Fishman, L; Hanson, V; Singsen, BH1
Aderet, NB; Biale, Y; Lewenthal, H1
Dam, M; Kiørboe, E1
Hudda, MM; Kim, CK; Pinel, JP; Wong, DJ; Yung, A1
Ishikawa, A; Kobayashi, S; Misawa, S; Tanaka, E; Uchida, E; Yamamoto, Y; Yasuhara, H1
Andrews, JS; Bortolotto, ZA; Bressler, K; Calderazzo-Filho, LS; Cavalheiro, EA; Löschmann, PA; Turski, L1
Etoh, H; Misawa, S; Tanaka, E1
Cennamo, M; Piccione, E; Ticconi, C1
Katahira, M; Kitagawa, YF; Kuroiwa, Y; Matsuda, K; Tanaka, E; Yoshida, T1
Bender, AS; Hertz, L1
Lee, EK; Walters, JR; Waszczak, BL1
Vorhees, CV2
Kohno, M; Kurata, N; Kuroiwa, Y; Tanaka, E; Yoshida, T1
Depaulis, A; Marescaux, C; Micheletti, G; Reis, J; Rumbach, L; Vergnes, M; Warter, JM1
Stumpf, DA1
Kobayashi, S; Kuroiwa, Y; Oguchi, K; Tanaka, E; Yasuhara, H1
Aramphongphan, A; Kobayashi, S; Kurata, N; Kuroiwa, Y; Oguchi, K; Tanaka, E; Yasuhara, H1
Deitrich, RA; Erwin, VG1
Gogerty, JH; Iorio, LC; Ryan, EA1
Killam, EK; Killam, KF; Naquet, R2
Glaser, GE; Grove, I; Marino, BB; Pincus, JH1
Millichap, JG2
Hooshmand, H1
Sayers, A; Stille, G1
Boshes, LD1
Banziger, R; Hane, D1
Olesen, OV1
Rümke, CL1
Mandel, HG; Riis, M1
Kutt, H; Louis, S1
Izquierdo, I2
Crawford, RD; Crichlow, EC; Johnson, DD1
Beam, RE1
Halpern, LM; Julien, RM2
Kutt, H1
Nolte, H; von Schnakenburg, K1
Cremers, HM; Verheesen, PE1
Berry, CA; Faingold, CL1
Perchalski, RJ; Wilder, BJ1
Izquierdo, I; Tannhauser, M1
Swinyard, EA1
Ando, J; Kiehi, Y1
Fukuta, T; Shimazono, Y1
Bimar, J; Killam, EK; Killam, KF; Naquet, R; Poncet, M1
Halpern, LM; Ward, AA1
Isaacs, ER; Lipman, IJ; Suter, CG1
Borgstedt, AD; Bryson, MF; Forbes, GB; Young, LW1
Danielsson, B1
Koe, BK; Weissman, A1
Ferngren, H; Paalzow, L2
Blackburn, WH; Napoli, MD; Wallin, RF1
Copsey, K; Deichmann, WB; Hamill, T; MacDonald, WE; MacQueen, J1
Downes, H; Karler, R; Ostlund, RE; Perry, RS1
Blum, B; Elazar, Z1
Southgate, PJ1
Caldeira, JA; Ramos, AO; Ramos, L1
Burba, JV1
Ferngren, H1
Carl, J; King, LJ1
Krupp, P1
Dang, HC; Visek, WJ1
Bartels, E; Rosenberg, P1
Bender, AD; Greene, L; Macko, E; Tedeschi, RE; Wilfon, G1
Albright, PS; Bruni, J1
Passarelli, F; Sagratella, S; Scotti de Carolis, A1
Czuczwar, SJ; Kleinrok, Z; Turski, L; Turski, W1
Kinoshita, H; Kuroiwa, Y; Tanaka, E; Yoshida, T1
Arai, M; Miura, S; Oana, Y1
Burnham, WM; King, GA; Livingston, KE1
Callaghan, DA; Schwark, WS1
Amano, T; Fujita, Y; Hanaya, R; Matsubayashi, H; Sasa, M; Serikawa, T; Ujihara, H; Uozumi, T1
Azarbayjani, F; Danielsson, BR1
Horie, T; Kitada, M; Ohmori, S; Sawa, Y; Tanaka, E; Taniguchi, T1
VAN DER SIJDE, HR; VASBINDER, H1
NARITA, Y1
HANSEN, HA; NORDQVIST, P; SOURANDER, P1
DUBOIS, EL1
LOEWE, S1
DRIVER, RL; ORDWAY, GL1

Reviews

10 review(s) available for phenobarbital and trimethadione

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The pregnant epileptic: a review and recommendations.
    Archives of neurology, 1979, Volume: 36, Issue:10

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Epilepsy; Female; Fetus; Humans; Infant, Newborn; Kinetics; Maternal-Fetal Exchange; Phenobarbital; Pregnancy; Pregnancy Complications; Time Factors; Trimethadione; Vitamin K Deficiency Bleeding

1979
[Problems of neurological drug therapy in pregnancy].
    La Clinica terapeutica, 1989, Apr-30, Volume: 129, Issue:2

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Antiparkinson Agents; Carbamazepine; Chelating Agents; Female; Fetus; Haloperidol; Humans; Nervous System Diseases; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Trimethadione; Valproic Acid

1989
Pharmacokinetics of anti-epileptic drugs in the dog: a review.
    Journal of veterinary pharmacology and therapeutics, 1985, Volume: 8, Issue:3

    Topics: Animals; Anticonvulsants; Blood Proteins; Carbamazepine; Clonazepam; Diazepam; Dog Diseases; Dogs; Epilepsy; Ethosuximide; Kinetics; Phenobarbital; Phenytoin; Primidone; Species Specificity; Trimethadione; Valproic Acid

1985
Relation of laboratory evaluation to clinical effectiveness of antiepileptic drugs.
    Epilepsia, 1969, Volume: 10, Issue:2

    Topics: Acetazolamide; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzazepines; Clinical Trials as Topic; Drug Tolerance; Electroencephalography; Electroshock; Epilepsy; Ethosuximide; Humans; Pentylenetetrazole; Phenobarbital; Phenytoin; Primidone; Seizures; Trimethadione; Urea

1969
Toxic effects of anticonvulsants: general principles.
    Pediatrics, 1974, Volume: 53, Issue:4

    Topics: Adrenocorticotropic Hormone; Adult; Anticonvulsants; Benzodiazepinones; Body Surface Area; Body Weight; Carbamazepine; Child; Chlorobenzenes; Diagnosis, Differential; Diazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Half-Life; Humans; Nitro Compounds; Phenobarbital; Phenytoin; Primidone; Succinimides; Tranquilizing Agents; Trimethadione

1974
Pharmacodynamic and pharmacokinetic measurements of antiepileptic drugs.
    Clinical pharmacology and therapeutics, 1974, Volume: 16, Issue:1

    Topics: Anticonvulsants; Chromatography, Gas; Dose-Response Relationship, Drug; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Trimethadione

1974
Laboratory evaluation of antiepileptic drugs. Review of laboratory methods.
    Epilepsia, 1969, Volume: 10, Issue:2

    Topics: Animals; Anticonvulsants; Biological Assay; Brain Injuries; Diagnosis; Electroconvulsive Therapy; Electroshock; Humans; Methionine Sulfoximine; Methods; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Seizures; Strychnine; Thiosemicarbazones; Trimethadione; Urea

1969
[Drug therapy of epilepsy].
    Naika. Internal medicine, 1967, Volume: 19, Issue:6

    Topics: Epilepsy; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Trimethadione; Urea

1967
The clinical pharmacology of antiepileptic drugs.
    Clinical neuropharmacology, 1984, Volume: 7, Issue:1

    Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Ethosuximide; Female; Half-Life; Humans; Intestinal Absorption; Kidney; Kidney Diseases; Kinetics; Liver Diseases; Phenobarbital; Phenytoin; Pregnancy; Primidone; Protein Binding; Tissue Distribution; Trimethadione; Valproic Acid

1984

Trials

1 trial(s) available for phenobarbital and trimethadione

ArticleYear
Relation of laboratory evaluation to clinical effectiveness of antiepileptic drugs.
    Epilepsia, 1969, Volume: 10, Issue:2

    Topics: Acetazolamide; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzazepines; Clinical Trials as Topic; Drug Tolerance; Electroencephalography; Electroshock; Epilepsy; Ethosuximide; Humans; Pentylenetetrazole; Phenobarbital; Phenytoin; Primidone; Seizures; Trimethadione; Urea

1969

Other Studies

99 other study(ies) available for phenobarbital and trimethadione

ArticleYear
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
The fetal trimethadione syndrome.
    The Journal of pediatrics, 1975, Volume: 87, Issue:2

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anthropometry; Child, Preschool; Developmental Disabilities; Ear, External; Epilepsy, Absence; Eye Abnormalities; Eyebrows; Female; Fetal Diseases; Fetus; Growth Disorders; Hand Deformities, Congenital; Hearing Disorders; Hernia, Inguinal; Humans; Hypospadias; Infant; Male; Microcephaly; Oxazoles; Palate; Phenobarbital; Pregnancy; Pregnancy Complications; Speech Disorders; Syndrome; Teratogens; Tooth Abnormalities; Trimethadione

1975
Mechaism of neuromuscular blockade with some antiepileptic drugs.
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:2

    Topics: Abdominal Muscles; Anesthetics, Local; Animals; Anticonvulsants; Cats; Diaphragm; Ethosuximide; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscles; Neuromuscular Blocking Agents; Neuromuscular Junction; Neuromuscular Nondepolarizing Agents; Phenobarbital; Phenytoin; Rabbits; Rats; Trimethadione

1976
Changes in sensitivity of mice to anticonvulsant drugs following bilateral olfactory bulb ablations.
    Japanese journal of pharmacology, 1977, Volume: 27, Issue:2

    Topics: Acetazolamide; Animals; Anticonvulsants; Chlordiazepoxide; Diazepam; Dose-Response Relationship, Drug; Electroshock; Male; Mice; Nitrazepam; Olfactory Bulb; Phenobarbital; Phenylacetates; Phenytoin; Trimethadione; Urea; Valproic Acid

1977
Effect of anticonvulsants on thalamic afterdischarge in rats and cats.
    Japanese journal of pharmacology, 1977, Volume: 27, Issue:6

    Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Cats; Diazepam; Electrocardiography; Electroencephalography; Female; Male; Phenobarbital; Phenytoin; Rats; Thalamus; Trimethadione; Valproic Acid

1977
Consecutive gas chromatographic determination of phenytoin, phenobarbital, primidone, phenylethylmalondiamide, carbamazepine, trimethadione, dimethadione, ethosuximide, and valproate from the same serum specimen.
    Epilepsia, 1978, Volume: 19, Issue:5

    Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Dimethadione; Ethosuximide; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Trimethadione; Valproic Acid

1978
Effect of anticonvulsants on spiking activity induced by cortical freezing in cats.
    Epilepsia, 1979, Volume: 20, Issue:1

    Topics: Acetazolamide; Animals; Anticonvulsants; Arousal; Carbamazepine; Cats; Diazepam; Electrocardiography; Electroencephalography; Female; Freezing; Gallamine Triethiodide; Immobilization; Male; Phenobarbital; Phenytoin; Taurine; Trimethadione; Valproic Acid; Visual Cortex

1979
Effect of anticonvulsants on cortical focal seizure in cats.
    Epilepsia, 1977, Volume: 18, Issue:1

    Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Cats; Diazepam; Electrocardiography; Epilepsies, Partial; Female; Heart; Male; Phenobarbital; Phenytoin; Seizures; Trimethadione; Valproic Acid

1977
American Academy of Pediatrics Committee on Drugs: anticonvulsants and pregnancy.
    Pediatrics, 1979, Volume: 63, Issue:2

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Cleft Lip; Cleft Palate; Epilepsy; Female; Heart Defects, Congenital; Humans; Hydantoins; Infant; Infant, Newborn; Intellectual Disability; Phenobarbital; Pregnancy; Pregnancy Complications; Trimethadione

1979
Evaluation of anticonvulsants in barbiturate withdrawal.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 202, Issue:2

    Topics: Animals; Anticonvulsants; Behavior, Animal; Cats; Dimethadione; Female; Humans; Male; Pentobarbital; Phenobarbital; Phenytoin; Seizures; Substance Withdrawal Syndrome; Time Factors; Trimethadione

1977
The temporal dimensions of anticonvulsant action of some newer benzodiazepines against metrazol induced seizures in mice and rats.
    Medical biology, 1977, Volume: 55, Issue:6

    Topics: Animals; Benzodiazepines; Clonazepam; Diazepam; Drug Evaluation, Preclinical; Ethosuximide; Female; Flurazepam; Male; Mice; Nitrazepam; Pentylenetetrazole; Phenobarbital; Seizures; Trimethadione

1977
Di-n-propylacetic acid--profile of anticonvulsant activity in mice.
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:2

    Topics: Animals; Anticonvulsants; Bicuculline; Dose-Response Relationship, Drug; Electroshock; Ethosuximide; Female; Male; Mice; Pentylenetetrazole; Phenobarbital; Picrotoxin; Seizures; Strychnine; Trimethadione; Valerates; Valproic Acid

1976
Congenital malformations in four siblings of a mother taking anticonvulsant drugs.
    American journal of diseases of children (1960), 1976, Volume: 130, Issue:8

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anticonvulsants; Child; Child, Preschool; Epilepsy, Tonic-Clonic; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Pregnancy; Primidone; Trimethadione

1976
Epilepsy and other seizure disorders in children: drug management.
    The Journal of school health, 1976, Volume: 46, Issue:8

    Topics: Acetazolamide; Anticonvulsants; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Primidone; Succinimides; Trimethadione

1976
Convulsant-anticonvulsant interactions on seizure activity and cortical acetylcholine release.
    European journal of pharmacology, 1977, Apr-07, Volume: 42, Issue:3

    Topics: Acetylcholine; Animals; Anticonvulsants; Bicuculline; Blood Pressure; Cerebral Cortex; Convulsants; Drug Interactions; Electroencephalography; Male; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; Seizures; Time Factors; Trimethadione

1977
Cardiac defects in children of mothers receiving anticonvulsant therapy during pregnancy.
    The Journal of pediatrics, 1976, Volume: 89, Issue:2

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Cleft Lip; Cleft Palate; Dimethadione; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Male; Mephobarbital; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Trimethadione

1976
Antinuclear antibodies and lupus-like syndromes in children receiving anticonvulsants.
    Pediatrics, 1976, Volume: 57, Issue:4

    Topics: Adolescent; Adult; Antibodies, Antinuclear; Anticonvulsants; Child; Child, Preschool; Ethosuximide; Female; Humans; Infant; Lupus Erythematosus, Systemic; Male; Mephenytoin; Phenobarbital; Phenytoin; Seizures; Succinimides; Trimethadione

1976
Congenital malformations due to anticonvulsive drugs.
    Obstetrics and gynecology, 1975, Volume: 45, Issue:4

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Anencephaly; Anticonvulsants; Birth Order; Cleft Lip; Cleft Palate; Epilepsy; Female; Fetal Death; Folic Acid; Folic Acid Antagonists; Hemorrhage; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Trimethadione

1975
[Current viewpoints in drug treatment of epilepsy, with reference to the most common drugs in current use].
    Ugeskrift for laeger, 1975, Oct-06, Volume: 137, Issue:41

    Topics: Anticonvulsants; Carbamazepine; Clonazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Trimethadione

1975
Drugs for epilepsy.
    The Medical letter on drugs and therapeutics, 1976, Mar-12, Volume: 18, Issue:6

    Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Trimethadione

1976
Tolerance to the anticonvulsant effects of phenobarbital, trimethadione, and clonazepam in kindled rats: cross tolerance to carbamazepine.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 41, Issue:1

    Topics: Amygdala; Animals; Anticonvulsants; Brain; Carbamazepine; Clonazepam; Drug Tolerance; Electrodes, Implanted; Electroshock; Kindling, Neurologic; Male; Pentylenetetrazole; Phenobarbital; Rats; Seizures; Stereotaxic Techniques; Trimethadione

1992
A simplified approach for evaluation of hepatic drug-oxidizing activity with a simultaneous determination of caffeine and trimethadione and their demethylated metabolites in rats with a selective cytochrome P-450 inducer.
    Biopharmaceutics & drug disposition, 1992, Volume: 13, Issue:4

    Topics: Animals; Caffeine; Cytochrome P-450 Enzyme System; Humans; Liver; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains; Trimethadione

1992
Substantia nigra regulates action of antiepileptic drugs.
    Brain research, 1990, Jun-18, Volume: 520, Issue:1-2

    Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroencephalography; Ethosuximide; Male; Microinjections; Midazolam; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Inbred Strains; Seizures; Substantia Nigra; Trimethadione

1990
The effects of selective cytochrome P-450 inducing agents on trimethadione metabolism as an indicator of hepatic drug-oxidizing capacity in rats.
    Research communications in chemical pathology and pharmacology, 1990, Volume: 68, Issue:3

    Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Liver; Male; Methylcholanthrene; Oxazoles; Phenobarbital; Rats; Rats, Inbred Strains; Safrole; Trimethadione

1990
Evaluation of the induction of hepatic drug-metabolizing enzymes in the rat and mouse treated with temazepam using trimethadione as the indicator.
    The Journal of toxicological sciences, 1985, Volume: 10, Issue:1

    Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Anti-Anxiety Agents; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Enzyme Induction; Liver; Male; Mice; Mice, Inbred ICR; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Temazepam; Trimethadione

1985
Evidence for involvement of the astrocytic benzodiazepine receptor in the mechanism of action of convulsant and anticonvulsant drugs.
    Life sciences, 1988, Volume: 43, Issue:6

    Topics: Animals; Anticonvulsants; Astrocytes; Barbiturates; Benzodiazepinones; Brain; Carbamazepine; Cells, Cultured; Convulsants; Diazepam; Ethosuximide; Mice; Neurons; Pentylenetetrazole; Phenobarbital; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Trimethadione; Valproic Acid

1988
Effects of anticonvulsant drugs on substantia nigra pars reticulata neurons.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:2

    Topics: Animals; Anticonvulsants; Carbamazepine; Clonazepam; Dose-Response Relationship, Drug; Ethosuximide; Male; Neurons; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Substantia Nigra; Trimethadione; Valproic Acid

1986
Fetal anticonvulsant exposure: effects on behavioral and physical development.
    Annals of the New York Academy of Sciences, 1986, Volume: 477

    Topics: Animals; Anticonvulsants; Female; Humans; Learning; Memory; Motor Activity; Oxazoles; Phenobarbital; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Reflex, Startle; Trimethadione

1986
Induction of cytochrome P-450 and related drug-oxidizing activities in muscone (3-methylcyclopentadecanone)-treated rats.
    Biochemical pharmacology, 1987, Dec-15, Volume: 36, Issue:24

    Topics: 5-Aminolevulinate Synthetase; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Antipyrine; Biotransformation; Cycloparaffins; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Trimethadione

1987
Antiepileptic drug evaluation in a new animal model: spontaneous petit mal epilepsy in the rat.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:2

    Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Electroencephalography; Epilepsy, Absence; Ethosuximide; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Trimethadione; Valproic Acid

1985
Anticonvulsant use during pregnancy.
    Clinical therapeutics, 1985, Volume: 7, Issue:2

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Epilepsy; Female; Fetal Death; Humans; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Risk; Trimethadione

1985
The effects of short-term administration of ibuprofen on trimethadione metabolism and antipyrine metabolite formation in the rat.
    Research communications in chemical pathology and pharmacology, 1985, Volume: 48, Issue:2

    Topics: Animals; Antipyrine; Ibuprofen; Liver; Male; Methylcholanthrene; Oxazoles; Phenobarbital; Rats; Rats, Inbred Strains; Trimethadione

1985
The effect of indomethacin on hepatic drug-oxidizing capacity in the rat: trimethadione and antipyrine metabolism as an indicator.
    Journal of pharmacobio-dynamics, 1985, Volume: 8, Issue:9

    Topics: Animals; Antipyrine; Half-Life; Indomethacin; Liver; Male; Methylcholanthrene; Mixed Function Oxygenases; Oxazoles; Oxidation-Reduction; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains; Trimethadione

1985
Inhibition of bovine brain aldehyde reductase by anticonvulsant compounds in vitro.
    Biochemical pharmacology, 1973, Oct-15, Volume: 22, Issue:20

    Topics: Aldehyde Oxidoreductases; Amobarbital; Animals; Anticonvulsants; Barbiturates; Brain; Cattle; Ethosuximide; Hydantoins; Hydrogen-Ion Concentration; In Vitro Techniques; Isomerism; Kinetics; Mephobarbital; NADP; Pentobarbital; Phenobarbital; Phenytoin; Spectrometry, Fluorescence; Spectrophotometry; Succinimides; Trimethadione

1973
Anticonvulsant testing with a new analeptic convulsant: N-sulfamoyl-hexahydro-azepine (Sah 41-178).
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 206, Issue:2

    Topics: Acetamides; Animals; Anticonvulsants; Azepines; Central Nervous System Stimulants; Chlordiazepoxide; Chlorpromazine; Diazepam; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Glutethimide; Haloperidol; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Strychnine; Sulfonamides; Trimethadione

1973
An animal model of light sensitive epilepsy.
    Electroencephalography and clinical neurophysiology, 1967, Volume: 22, Issue:6

    Topics: Adaptation, Physiological; Animals; Anticonvulsants; Cerebral Cortex; Chlorpromazine; Diazepam; Electroencephalography; Electromyography; Electrophysiology; Evoked Potentials; Eye Movements; Female; Haplorhini; Light; Male; Noise; Pentylenetetrazole; Phenobarbital; Photosensitivity Disorders; Seizures; Sleep; Trimethadione

1967
Evoked potential studies in response to light in the baboon (Papio papio).
    Electroencephalography and clinical neurophysiology, 1967

    Topics: Animals; Cerebral Cortex; Chlorpromazine; Diazepam; Epilepsy; Evoked Potentials; Haplorhini; Light; Myoclonus; Phenobarbital; Trimethadione; Vision, Ocular

1967
Studies on the mechanism of action of diphenylhydantoin.
    Archives of neurology, 1970, Volume: 22, Issue:6

    Topics: Adenosine Triphosphatases; Animals; Biological Transport; Crustacea; Cyanides; Hypoxia; Neurons; Ouabain; Peripheral Nerves; Phenobarbital; Phenytoin; Potassium; Schwann Cells; Sodium; Tetrodotoxin; Trimethadione

1970
Drug treatment of convulsive disorders.
    The New England journal of medicine, 1972, Mar-02, Volume: 286, Issue:9

    Topics: Acetazolamide; Adrenocorticotropic Hormone; Adult; Anticonvulsants; Barbiturates; Child; Diazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant; Myoclonus; Oxazoles; Phenobarbital; Phenytoin; Primidone; Pyrrolidinones; Seizures; Trimethadione

1972
Motor convulsions and EEG during maximal electroshock in the rat.
    International journal of neuropharmacology, 1967, Volume: 6, Issue:3

    Topics: Animals; Anticonvulsants; Cerebral Cortex; Cornea; Electric Stimulation; Electroencephalography; Electroshock; Muscles; Phenobarbital; Phenytoin; Primidone; Rats; Seizures; Stress, Physiological; Succinimides; Thiazines; Trimethadione

1967
Days of our years.
    IMJ. Illinois medical journal, 1967, Volume: 131, Issue:5

    Topics: Anticonvulsants; Bromides; Epilepsy; Female; History, 20th Century; Humans; Male; Phenobarbital; Trimethadione

1967
Evaluation of a new convulsant for anticonvulsant screening.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 167, Issue:2

    Topics: Acetazolamide; Animals; Anticonvulsants; Cats; Central Nervous System Stimulants; Chlordiazepoxide; Diazepam; Ethosuximide; Female; Male; Mice; Phenobarbital; Phenytoin; Pyrimidines; Thiazines; Trimethadione

1967
Determination of phenobarbital and phenytoin in serum by ultraviolet spectrophotometry.
    Scandinavian journal of clinical and laboratory investigation, 1967, Volume: 20, Issue:1

    Topics: Barbiturates; Chromatography, Thin Layer; Humans; Phenobarbital; Phenytoin; Salicylamides; Spectrophotometry; Sulfadimethoxine; Sulfamethoxypyridazine; Thiazines; Trimethadione; Ultraviolet Rays

1967
Increased susceptibility of mice to seizures after some anticonvulsant drugs.
    European journal of pharmacology, 1967, Volume: 1, Issue:5

    Topics: Animals; Anticonvulsants; Bemegride; Central Nervous System Stimulants; Drug Synergism; Electroshock; Ethionine; Female; Hydantoins; Male; Methods; Mice; Oxazines; Pentylenetetrazole; Phenobarbital; Phenytoin; Primidone; Rats; Seizures; Trimethadione

1967
Interference of barbiturates with pyrimidine incorporation. II. Structural specificity of the inhibition of orotate uptake in Bacillus cereus.
    Biochemical pharmacology, 1970, Volume: 19, Issue:6

    Topics: Amobarbital; Bacillus cereus; Barbiturates; Bemegride; Biological Transport; Carbon Isotopes; Carboxylic Acids; Central Nervous System Stimulants; Chemical Phenomena; Chemistry; Chemistry, Physical; Chlorine; Chlorpromazine; Glutethimide; Hexobarbital; Hydantoins; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; Orotic Acid; Pentobarbital; Phenobarbital; Phenytoin; Primidone; Solubility; Succinimides; Thiopental; Thymine; Trimethadione; Tromethamine; Uracil; Urea

1970
Anticonvulsant drugs. I. Patho-physiological and pharmacological aspects.
    Drugs, 1972, Volume: 4, Issue:3

    Topics: Acetates; Acetazolamide; Anticonvulsants; Carbamazepine; Diazepam; Dibenzazepines; Electroencephalography; Epilepsies, Partial; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Succinimides; Thiazines; Trimethadione

1972
Effect on pseudoconditioning of drugs with known central nervous activity.
    Psychopharmacologia, 1974, Volume: 38, Issue:3

    Topics: Amobarbital; Animals; Avoidance Learning; Behavior, Animal; Caffeine; Cannabis; Chlorpromazine; Conditioning, Psychological; Depression, Chemical; Diazepam; Dibenzylchlorethamine; Female; Meprobamate; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Rats; Stimulation, Chemical; Strychnine; Trimethadione

1974
Epileptiform seizures in domestic fowl. IV. The effects of anticonvulsant drugs.
    Canadian journal of physiology and pharmacology, 1974, Volume: 52, Issue:5

    Topics: Animals; Anticonvulsants; Chickens; Diazepam; Electroencephalography; Phenobarbital; Phenytoin; Photic Stimulation; Seizures; Trimethadione

1974
Broad-spectrum simultaneous GLC assay of nonderivatized antiepileptic drugs.
    The American journal of medical technology, 1974, Volume: 40, Issue:5

    Topics: Anticonvulsants; Barbiturates; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Quality Control; Trimethadione

1974
Augmentation of cerebellar Purkinje cell discharge rate after diphenylhydantoin.
    Epilepsia, 1972, Volume: 13, Issue:3

    Topics: Acetazolamide; Action Potentials; Cerebellum; Electroencephalography; Epilepsy; Phenobarbital; Phenytoin; Purkinje Cells; Trimethadione

1972
Effects of diphenylhydantoin and other antiepileptic drugs on epileptiform activity and Purkinje cell discharge rates.
    Epilepsia, 1972, Volume: 13, Issue:3

    Topics: Acetazolamide; Action Potentials; Animals; Anticonvulsants; Blood Pressure; Cats; Cerebellum; Electroencephalography; Epilepsy; Penicillins; Phenobarbital; Phenytoin; Purkinje Cells; Trimethadione

1972
[Morphological and pharmacological-toxicological aspects of hyperoxia].
    International journal of clinical pharmacology, therapy and toxicology, 1973, Volume: 7, Issue:4

    Topics: Aminobutyrates; Animals; Atmospheric Pressure; Brain Diseases; Diazepam; Ganglia; Humans; Lung; Lung Diseases; Muscle Cramp; Oxygen; Partial Pressure; Phenobarbital; Phentolamine; Phenytoin; Pulmonary Edema; Rats; Time Factors; Trimethadione; Tromethamine

1973
The effect of some anticonvulsant drugs on leptazol and bicuculline induced acetylcholine efflux from rat cerebral cortex.
    British journal of pharmacology, 1973, Volume: 47, Issue:3

    Topics: Acetylcholine; Alkaloids; Animals; Anticonvulsants; Cerebral Cortex; Dioxoles; Dose-Response Relationship, Drug; Electroencephalography; Isoquinolines; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; Seizures; Trimethadione

1973
A rapid method for the estimation of anti-epileptic drugs in blood serum by gas-liquid chromatography.
    Clinica chimica acta; international journal of clinical chemistry, 1973, Nov-15, Volume: 48, Issue:4

    Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Epilepsy; Ethosuximide; Evaluation Studies as Topic; Humans; Mephobarbital; Methods; Methylation; Microchemistry; Phenobarbital; Phenytoin; Primidone; Succinimides; Temperature; Time Factors; Trimethadione

1973
Quantitative evaluation of the pentylenetetrazol-anticonvulsant interaction on the EEG of the cat.
    European journal of pharmacology, 1973, Volume: 24, Issue:3

    Topics: Animals; Anticonvulsants; Cats; Cerebral Cortex; Computers; Drug Interactions; Electroencephalography; Hippocampus; Pentylenetetrazole; Phenobarbital; Phenytoin; Reticular Formation; Thalamus; Time Factors; Trimethadione

1973
Letter: GLC microdetermination of plasma anticonvulsant levels.
    Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:5

    Topics: Anticonvulsants; Chromatography, Gas; Ethosuximide; Humans; Methods; Phenobarbital; Phenytoin; Primidone; Trimethadione

1974
Effect of seizures and anticonvulsant agents on hippocampal RNA concentration.
    Pharmacology, 1974, Volume: 11, Issue:3

    Topics: Anesthesia, General; Animals; Anticonvulsants; Cannabis; Cerebral Cortex; Depression, Chemical; Electric Stimulation; Electroshock; Glucose; Hippocampus; Hyponatremia; Male; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; RNA; Seizures; Time Factors; Trimethadione; Urethane

1974
Effect of anticonvulsant drugs on the number of afferent stimuli needed to cause a hippocampal seizure discharge.
    Pharmacology, 1974, Volume: 11, Issue:3

    Topics: Animals; Anticonvulsants; Cannabis; Dose-Response Relationship, Drug; Electric Stimulation; Electroshock; Evoked Potentials; Hippocampus; Injections, Intraperitoneal; Neurons, Afferent; Phenobarbital; Phenytoin; Rats; Seizures; Time Factors; Trimethadione

1974
[Ethosuximide in treatment of petit mal epilepsy].
    No to shinkei = Brain and nerve, 1965, Volume: 17, Issue:8

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Electroencephalography; Epilepsy, Absence; Ethosuximide; Female; Humans; Male; Phenobarbital; Phenytoin; Trimethadione

1965
[A new animal model in study of the epilepsy: the baboon, Papio papio].
    Actualites neurophysiologiques, 1968, Volume: 8

    Topics: Animals; Cerebral Cortex; Diazepam; Electroencephalography; Electromyography; Evoked Potentials; Eye Movements; Haplorhini; Hypnotics and Sedatives; Light; Motor Activity; Noise; Phenobarbital; Seizures; Trimethadione

1968
The hyperexcitable neuron as a model for the laboratory analysis of anticonvulsant drugs.
    Epilepsia, 1969, Volume: 10, Issue:2

    Topics: Acetazolamide; Action Potentials; Aluminum; Animals; Behavior, Animal; Cats; Cerebral Cortex; Electroencephalography; Haplorhini; Hydroxides; Models, Biological; Neurons; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Time Factors; Trimethadione

1969
Petit mal status. A variety of non-convulsive status epilepticus.
    Diseases of the nervous system, 1971, Volume: 32, Issue:5

    Topics: Adolescent; Adult; Child; Child, Preschool; Diagnosis, Differential; Diazepam; Electroencephalography; Epilepsy, Absence; Female; Humans; Male; Menstruation; Mental Processes; Middle Aged; Phenobarbital; Seizures; Trimethadione

1971
Long-term administration of antiepileptic drugs and the development of rickets.
    The Journal of pediatrics, 1972, Volume: 81, Issue:1

    Topics: Alkaline Phosphatase; Anticonvulsants; Calcium; Diazepam; Ethosuximide; Female; Gluconates; Humans; Infant; Mephobarbital; Osteomalacia; Phenobarbital; Phenytoin; Phosphorus; Primidone; Radiography; Rickets; Seizures; Time Factors; Trimethadione; Vitamin D

1972
[Anticonvulsants. 1. Chemical survey].
    Lakartidningen, 1971, Oct-18, Volume: 68

    Topics: Anticonvulsants; Barbiturates; Carbamazepine; Chemical Phenomena; Chemistry; Diazepam; Hydantoins; Phenobarbital; Primidone; Pyrrolidines; Trimethadione

1971
m-Fluorotyrosine convulsions and mortality: relationship to catecholamine and citrate metabolism.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 155, Issue:1

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anticonvulsants; Atropine; Azoles; Brain; Chlordiazepoxide; Chlorpromazine; Citrates; Dihydroxyphenylalanine; Disulfiram; Drug Antagonism; Drug Synergism; Kidney; Lysergic Acid Diethylamide; Male; Methyldopa; Mice; Morphine; Nialamide; Norepinephrine; Pargyline; Phenobarbital; Phenytoin; Reserpine; Seizures; Serotonin; Strychnine; Tetrabenazine; Trimethadione; Tyrosine; Urea

1967
High frequency electro-shock seizures and their antagonism during postnatal development in the mouse. II. Effects of phenobarbital sodium, mephobarbital, trimethadione, dimethadione, ethosuximide and acetazolamide.
    Acta pharmacologica et toxicologica, 1969, Volume: 27, Issue:4

    Topics: Acetazolamide; Age Factors; Animals; Animals, Newborn; Anticonvulsants; Electroshock; Ethosuximide; Mephobarbital; Mice; Phenobarbital; Seizures; Trimethadione

1969
Pharmacologic interactions of albutoin with other anticonvulsant drugs.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 174, Issue:2

    Topics: Animals; Anticonvulsants; Drug Synergism; Electroshock; Hydantoins; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Trimethadione

1970
Effect of parathion on liver microsomal enzyme activites induced by organochlorine pesticides and drugs in female rats.
    Internationales Archiv fur Arbeitsmedizin, 1970, Volume: 26, Issue:1

    Topics: Animals; Azo Compounds; Chlordan; DDT; Dimenhydrinate; Female; Hydrocarbons, Halogenated; Microsomes, Liver; Naphthalenes; Oxidoreductases; Paraldehyde; Parathion; Phenobarbital; Phenytoin; Rats; Trimethadione

1970
A study of the excitatory effects of barbiturates.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 175, Issue:3

    Topics: Animals; Anticonvulsants; Barbiturates; Chemical Phenomena; Chemistry; Injections, Intravenous; Male; Mice; Pentobarbital; Phenobarbital; Phenytoin; Seizures; Stereoisomerism; Trimethadione

1970
Effect of drugs on interictal spikes and after-discharges in experimental epilepsy.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 189, Issue:2

    Topics: Animals; Anticonvulsants; Cats; Electroencephalography; Glutethimide; Hippocampus; Hydantoins; Meprobamate; Phenobarbital; Receptors, Drug; Seizures; Trimethadione; Tungsten

1971
A comparison of the anticonvulsant properties of 2-diethylaminopento-4-ynoyl-2',6'-xylidide (WY 21745) with lignocaine, phenytoin, phenobarbitone and trimethadione.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 191, Issue:2

    Topics: Anesthetics, Local; Animals; Anticonvulsants; Drug Antagonism; Electroshock; Lethal Dose 50; Lidocaine; Mice; Oxazoles; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Trimethadione

1971
[Eye hypotension due to anticonvulsants in rabbits].
    Arquivos brasileiros de oftalmologia, 1967, Volume: 30, Issue:5

    Topics: Animals; Anticonvulsants; Female; Intraocular Pressure; Male; Oxazoles; Phenobarbital; Phenytoin; Rabbits; Trimethadione

1967
Studies on electrically induced-seizures and their antagonism by anticonvulsants during neonatal development in the mouse.
    Acta pharmacologica et toxicologica, 1967, Volume: 25

    Topics: Acetazolamide; Animals; Animals, Newborn; Anticonvulsants; Electric Stimulation; Ethosuximide; Mice; Phenobarbital; Phenytoin; Seizures; Trimethadione

1967
Influence of several drugs on the in vivo and in vitro activity of mammalian hepatic azo-reductase.
    Canadian journal of biochemistry, 1968, Volume: 46, Issue:4

    Topics: Animals; Caffeine; Guanethidine; Guinea Pigs; In Vitro Techniques; Iproniazid; Isoniazid; Liver; Nitrofurantoin; Oxidoreductases; Pentylenetetrazole; Phenobarbital; Phenylbutazone; Phenytoin; Rabbits; Rats; Sulfinpyrazone; Sulfonic Acids; Trimethadione

1968
Further studies on chemically induced siezures and their antagonism by anticonvulsants during postnatal development in the mouse.
    Acta pharmacologica et toxicologica, 1968, Volume: 26, Issue:2

    Topics: Animals; Animals, Newborn; Anticonvulsants; Brain; Mice; Pentylenetetrazole; Phenobarbital; Picrotoxin; Seizures; Trimethadione

1968
Effects of antiepileptic drugs on brain energy reserves during convulsions.
    Journal of neurochemistry, 1969, Volume: 16, Issue:4

    Topics: Adenosine Triphosphate; Animals; Anticonvulsants; Brain Chemistry; Cerebral Cortex; Electroshock; Glucose; Lactates; Mice; Phenobarbital; Phenytoin; Phosphocreatine; Seizures; Trimethadione

1969
[Electrophysiological studies on the mechanism of action of antiepileptics in animal experiments].
    Helvetica paediatrica acta, 1969, Volume: 24, Issue:3

    Topics: Animals; Anticonvulsants; Axons; Cats; Cerebral Cortex; Electric Stimulation; Hippocampus; Neural Conduction; Phenobarbital; Phenytoin; Rabbits; Spinal Cord; Synapses; Thalamus; Trimethadione

1969
Antagonism of urease toxicity by chemical agents and antisera.
    Toxicology and applied pharmacology, 1966, Volume: 8, Issue:2

    Topics: Alloxan; Animals; Anticonvulsants; Arginine; Barbiturates; Glutamates; Immune Sera; Injections, Intraperitoneal; Male; Mice; Pentobarbital; Phenobarbital; Phenytoin; Rats; Trimethadione; Urease

1966
Drug effects on the spontaneous electrical activity of the squid giant axon.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 155, Issue:3

    Topics: Acetylcholine; Action Potentials; Animals; Anticonvulsants; Atropine; Axons; Barbiturates; Bromides; Chloroform; Chlorpheniramine; Chlorpromazine; Curare; Dopamine; Electrophysiology; Ethanol; Ethers; Evoked Potentials; Hydantoins; Mollusca; Muscles; Nortropanes; Parasympatholytics; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Procaine; Serotonin; Strychnine; Tetracaine; Tremorine; Trihexyphenidyl; Trimethadione

1967
Pharmacological properties of the isopropyl ester of o-sulfamoyl-benzoic acid.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 168, Issue:1

    Topics: Animals; Behavior, Animal; Benzoates; Carbamates; Carisoprodol; Chlordiazepoxide; Chlormezanone; Chlorzoxazone; Dogs; Drug Antagonism; Electroshock; Male; Mephenesin; Meprobamate; Methocarbamol; Mice; Muscles; Pentobarbital; Phenethylamines; Phenobarbital; Phenytoin; Rats; Reflex; Seizures; Sleep; Strychnine; Trimethadione; Zoxazolamine

1967
Fetal anticonvulsant syndrome in rats: dose- and period-response relationships of prenatal diphenylhydantoin, trimethadione and phenobarbital exposure on the structural and functional development of the offspring.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Behavior, Animal; Developmental Disabilities; Dose-Response Relationship, Drug; Female; Fetus; Gestational Age; Humans; Locomotion; Oxazoles; Phenobarbital; Phenytoin; Pregnancy; Rats; Rats, Inbred Strains; Reflex, Startle; Swimming; Syndrome; Time Factors; Trimethadione

1983
An EEG investigation on the effects of phencyclidine on pentylentetrazol convulsions in rats and rabbits.
    Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 266, Issue:2

    Topics: Animals; Electroencephalography; Male; Pentylenetetrazole; Phencyclidine; Phenobarbital; Rabbits; Rats; Rats, Inbred Strains; Seizures; Species Specificity; Trimethadione

1983
Effects of some antiepileptic drugs in pentetrazol-induced convulsions in mice lesioned with kainic acid.
    Epilepsia, 1981, Volume: 22, Issue:4

    Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Diazepam; Dose-Response Relationship, Drug; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Mice; Pentylenetetrazole; Phenobarbital; Pyrrolidines; Seizures; Succinimides; Trimethadione; Valproic Acid

1981
Studies on the trimethadione metabolism as a tool for the assessment of drug-metabolizing capacity using plasma and urine of rats pretreated with phenobarbital and 3-methylcholanthrene.
    Journal of pharmacobio-dynamics, 1982, Volume: 5, Issue:3

    Topics: Animals; Biotransformation; Creatinine; Glucaric Acid; Hydrogen-Ion Concentration; Liver; Male; Methylcholanthrene; Oxazoles; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains; Time Factors; Trimethadione

1982
[A study of effects on antiepileptic drugs upon the hippocampal afterdischarge (author's transl)].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1980, Volume: 82, Issue:1

    Topics: Animals; Anticonvulsants; Carbamazepine; Cats; Electric Stimulation; Female; Hippocampus; Male; Phenobarbital; Phenytoin; Seizures; Trimethadione

1980
Flash-evoked afterdischarge in rat as a model of the absence seizure: dose-response studies with therapeutic drugs.
    Epilepsia, 1980, Volume: 21, Issue:5

    Topics: Acetazolamide; Animals; Dose-Response Relationship, Drug; Ethosuximide; Evoked Potentials; Male; Mephenytoin; Phenobarbital; Phenytoin; Photic Stimulation; Rats; Seizures; Trimethadione

1980
Pharmacological modification of amygdaloid-kindled seizures.
    Neuropharmacology, 1980, Volume: 19, Issue:11

    Topics: Amygdala; Animals; Diazepam; Electric Stimulation; Electrodes, Implanted; Ketamine; Male; Phenobarbital; Phenytoin; Rats; Seizures; Trimethadione

1980
Effect of antiepileptic drugs on absence-like seizures in the tremor rat.
    Epilepsia, 1995, Volume: 36, Issue:9

    Topics: Animals; Anticonvulsants; Data Interpretation, Statistical; Drug Therapy, Combination; Electroencephalography; Epilepsy, Absence; Ethosuximide; Female; Injections, Intraperitoneal; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred WKY; Rats, Mutant Strains; Seizures; Time Factors; Trimethadione; Valproic Acid

1995
Pharmacologically induced embryonic dysrhythmia and episodes of hypoxia followed by reoxygenation: a common teratogenic mechanism for antiepileptic drugs?
    Teratology, 1998, Volume: 57, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Arrhythmias, Cardiac; Carbamazepine; Female; Fetus; Heart; Humans; Hypoxia; Mice; Mice, Inbred C57BL; Phenobarbital; Phenytoin; Pregnancy; Rats; Trimethadione

1998
Trimethadione metabolism and microsomal monooxygenases in untreated and phenobarbital-treated rhesus monkeys.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1998, Volume: 120, Issue:2

    Topics: Aniline Hydroxylase; Animals; Anticonvulsants; Cytochrome P-450 Enzyme System; Dimethadione; Enzyme Induction; Isoenzymes; Macaca mulatta; Male; Microsomes, Liver; Oxidoreductases, N-Demethylating; Oxidoreductases, O-Demethylating; Phenobarbital; Trimethadione

1998
[Titrimetric determination of mixtures of trimethadione and phenobarbital or phenylmethylbarbital].
    Pharmaceutisch weekblad, 1953, Nov-21, Volume: 88, Issue:47-48

    Topics: Anticonvulsants; Barbiturates; Humans; Phenobarbital; Titrimetry; Trimethadione

1953
A study of experimental intoxication of antiepileptic drugs (phenobarbital, 5-5-diphenyl-hydantoin, tridione).
    Folia psychiatrica et neurologica japonica, 1960, Volume: 14

    Topics: Anticonvulsants; Biphenyl Compounds; Diphenhydramine; Hydantoins; Imidazoles; Phenobarbital; Trimethadione

1960
MEGALOBLASTIC ANEMIA AND NEUROLOGIC DISTURBANCES COMBINED WITH FOLIC ACID DEFICIENCY. OBSERVATIONS ON AN EPILEPTIC PATIENT TREATED WITH ANTICONVULSANTS.
    Acta medica Scandinavica, 1964, Volume: 176

    Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Avitaminosis; Barbiturates; Brain Diseases; Central Nervous System Diseases; Cerebellar Diseases; Drug Therapy; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Neurologic Manifestations; Pathology; Phenobarbital; Phenytoin; Spinal Cord; Spinal Nerves; Toxicology; Trimethadione

1964
Toxic hepatic necrosis associated with taking dilantin, tridione and phenobarbital; report of a case.
    American journal of clinical pathology, 1950, Volume: 20, Issue:2

    Topics: Aged; Barbital; Hepatitis; Humans; Hydantoins; Liver; Liver Diseases; Phenobarbital; Phenytoin; Trimethadione

1950
Anticonvulsant actions of trimethadione-phenobarbital and trimethadione-diphenylhydantoin combinations.
    Federation proceedings, 1948, Volume: 7, Issue:1 Pt 1

    Topics: Anticonvulsants; Humans; Phenobarbital; Phenytoin; Seizures; Trimethadione

1948
Comparative anticonvulsant actions of isopropyl alcohol, diphenylhydantoin, phenobarbital and tridione.
    Federation proceedings, 1947, Volume: 6, Issue:1

    Topics: 1-Propanol; 2-Propanol; Anticonvulsants; Humans; Phenobarbital; Phenytoin; Propanols; Seizures; Trimethadione

1947