phenobarbital has been researched along with trichloroethylene in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (80.00) | 18.7374 |
| 1990's | 4 (10.00) | 18.2507 |
| 2000's | 3 (7.50) | 29.6817 |
| 2010's | 1 (2.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duffy, EM; Jorgensen, WL | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Frimmer, M; Homann, J; Rufeger, U | 1 |
| Carlson, GP; White, JF | 2 |
| Barth, ML; Cornish, HH; Ling, B | 1 |
| Banerjee, S; Van Duuren, BL | 2 |
| Allemand, H; Benhamou, JP; DeGott, C; Descatoire, V; Feldmann, G; Pessayre, D | 1 |
| Bingham, E; Dalbey, W | 1 |
| Bailey, K; Boor, PJ; Moslen, MT; Reynolds, ES; Szabo, S | 1 |
| Elovaara, E; Gelboin, HV; Nakajima, T; Park, SS; Vainio, H; Wang, RS | 1 |
| Hampton, JA; Hartnett, JA; Klaunig, JE; Olson, MJ; Schafer, LD; Siglin, JC; Weghorst, CM | 1 |
| Nakajima, T; Nakano, M; Okino, T | 1 |
| Murayama, N; Nakajima, T; Sato, A; Wang, RS | 1 |
| Abdel-Rahman, MS; Farghali, H; Kadry, AM | 1 |
| Meierhenry, EF; Milman, HA; Story, DL; Tyson, CA | 1 |
| Bull, RJ; Nelson, MA | 1 |
| Kaneko, T; Nakajima, T; Okino, T; Okuyama, S; Sato, A; Yonekura, I | 1 |
| Herren-Freund, SL; Khoury, MD; Olson, G; Pereira, MA | 1 |
| Boisset, M; Boudene, C; Cluet, JL | 1 |
| Dekant, W; Henschler, D; Metzler, M; Schulz, A | 1 |
| Nakajima, T; Okuyama, S; Sato, A; Yonekura, I | 1 |
| Rösen, P; Stier, A | 1 |
| Carlson, GP | 1 |
| Leibman, KC | 2 |
| Ikeda, M; Imanura, T | 1 |
| Barth, ML; Cornish, HH; Ling, BP | 1 |
| Clauberg, G | 1 |
| Leibman, KC; McAllister, WJ | 1 |
| Couri, D; Milks, MM | 1 |
| Fujita, H; Ikeda, M; Koizumi, A; Kumai, M; Sadamoto, T; Yamamoto, M | 1 |
| Buckiová, D; Musil, J; Nováková, V; Sollová, H; Táborský, O; Výborný, P | 1 |
| Moslen, MT; Reynolds, ES | 1 |
| Ikeda, M; Miyake, Y; Ogata, M; Ohmori, S | 1 |
| Finch, RA; Fort, DJ; Rogers, RL; Stover, EL | 1 |
| BENTLEY, HB | 1 |
| FAGER, CA | 1 |
2 review(s) available for phenobarbital and trichloroethylene
| Article | Year |
|---|---|
Differences in rat liver enzyme-altered foci produced by chlorinated aliphatics and phenobarbital.
Topics: Animals; Ethane; Ethylene Dichlorides; Hydrocarbons, Chlorinated; Isomerism; Liver; Male; Phenobarbital; Rats; Tetrachloroethylene; Trichloroethanes; Trichloroethylene | 1986 |
Biological half-life of trichloroethylene and tetrachloroethylene in human subjects.
Topics: Adult; Animals; Biological Assay; Biological Transport; Cricetinae; Drug Tolerance; Environmental Exposure; Enzyme Induction; Female; Half-Life; Humans; Male; Middle Aged; Occupational Medicine; Phenobarbital; Premedication; Rats; Tetrachloroethylene; Trichloroacetic Acid; Trichloroethylene | 1973 |
38 other study(ies) available for phenobarbital and trichloroethylene
| Article | Year |
|---|---|
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
[Inhibition by diethyldithiocarbamate (DEDTC) of acute hepatotoxic effects induced by polyhalogenated hydrocarbons (PHHC)].
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Ditiocarb; Glutathione; Halothane; Hydrocarbons, Halogenated; Liver Diseases; Male; Microcirculation; Perfusion; Phenobarbital; Rats; Thiocarbamates; Trichloroethylene | 1976 |
Influence of alterations in drug metabolism on spontaneous and epinephrine-induced cardiac arrhythmias in animals exposed to trichloroethylene.
Topics: Animals; Aroclors; Arrhythmias, Cardiac; Biphenyl Compounds; Diethylamines; Drug Interactions; Electrocardiography; Enzyme Inhibitors; Epinephrine; Male; Phenobarbital; Proadifen; Rabbits; Rats; Trichloroethylene | 1979 |
Influence of aliphatic alcohols on the hepatic response to halogenated olefins.
Topics: Alcohols; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chloroform; Drug Synergism; Environmental Exposure; Ethanol; Hydrocarbons, Chlorinated; Liver; Phenobarbital; Rats; Trichloroethylene | 1977 |
Covalent binding of the carcinogen trichloroethylene to hepatic microsomal proteins and to exogenous DNA in vitro.
Topics: Animals; DNA; Female; In Vitro Techniques; Male; Methylcholanthrene; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Microsomes, Liver; Organ Specificity; Phenobarbital; Proteins; Rats; Sex Factors; Species Specificity; Trichloroethylene | 1978 |
Metabolic activation of trichloroethylene into a chemically reactive metabolite toxic to the liver.
Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Cobalt; Glutathione; In Vitro Techniques; Male; Microsomes, Liver; Muscle Proteins; Phenobarbital; Protein Binding; Rats; Trichloroethylene | 1978 |
Metabolism of trichloroethylene by the isolated perfused lung.
Topics: Animals; Ethanol; Glucose; Guinea Pigs; In Vitro Techniques; Intubation, Intratracheal; Lung; Perfusion; Phenobarbital; Rats; Time Factors; Trichloroethylene | 1978 |
Trichloroethylene-induced deactivation of cytochrome P-450 and loss of liver glutathione in vivo.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Depression, Chemical; Drug Interactions; Enzyme Induction; Liver; Male; Microsomes, Liver; Phenobarbital; Rats; Time Factors; Trichloroethylene | 1977 |
Covalent interaction of metabolites of the carcinogen trichloroethylene in rat hepatic microsomes.
Topics: Animals; Epoxy Compounds; Flavonoids; Male; Microsomes, Liver; Phenobarbital; Proadifen; Protein Binding; Rats; Trichloroethylene | 1976 |
A comparative study on the contribution of cytochrome P450 isozymes to metabolism of benzene, toluene and trichloroethylene in rat liver.
Topics: Animals; Antibodies, Monoclonal; Benzene; Chloral Hydrate; Cytochrome P-450 Enzyme System; Ethanol; Isoenzymes; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains; Substrate Specificity; Toluene; Trichloroethylene | 1992 |
Correlation between species and tissue sensitivity to chemical carcinogenesis in rodents and the induction of DNA synthesis.
Topics: Animals; Barbiturates; Carcinogens; Cell Division; DNA Replication; Female; Gasoline; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred Strains; Mitotic Index; Organ Specificity; Phenobarbital; Rats; Rats, Inbred F344; Species Specificity; Trichloroethylene | 1991 |
Morphological and biochemical analyses of trichloroethylene hepatotoxicity: differences in ethanol- and phenobarbital-pretreated rats.
Topics: Animals; Benzene; Cytochrome P-450 Enzyme System; Ethanol; Liver; Male; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains; Trichloroethylene | 1991 |
Three forms of trichloroethylene-metabolizing enzymes in rat liver induced by ethanol, phenobarbital, and 3-methylcholanthrene.
Topics: Animals; Chloral Hydrate; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethanol; Hydroxylation; Isoenzymes; Kinetics; Liver; Male; Methylcholanthrene; Microsomes; Phenobarbital; Rats; Rats, Inbred Strains; Trichloroethylene | 1990 |
Toxicity and metabolism of trichloroethylene in rat hepatocytes.
Topics: Alanine Transaminase; Animals; Chromatography, High Pressure Liquid; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Trichloroethylene | 1989 |
Induction of strand breaks in DNA by trichloroethylene and metabolites in rat and mouse liver in vivo.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biotransformation; DNA; DNA Damage; Dose-Response Relationship, Drug; Ethanol; Liver; Male; Mice; Phenobarbital; Rats; Rats, Inbred Strains; Species Specificity; Trichloroethylene | 1988 |
Ethanol-induced enhancement of trichloroethylene metabolism and hepatotoxicity: difference from the effect of phenobarbital.
Topics: Alanine Transaminase; Alcoholic Intoxication; Animals; Dose-Response Relationship, Drug; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Trichloroethylene | 1988 |
The carcinogenicity of trichloroethylene and its metabolites, trichloroacetic acid and dichloroacetic acid, in mouse liver.
Topics: Acetates; Adenoma; Animals; Body Weight; Dichloroacetic Acid; Drug Synergism; Ethylnitrosourea; Liver Neoplasms, Experimental; Male; Mice; Organ Size; Phenobarbital; Trichloroacetic Acid; Trichloroethylene | 1987 |
Effect of pretreatment with cimetidine or phenobarbital on lipoperoxidation in carbon tetrachloride- and trichloroethylene-dosed rats.
Topics: Alkanes; Animals; Carbon Tetrachloride; Cimetidine; Dose-Response Relationship, Drug; In Vitro Techniques; Lipid Peroxides; Liver; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Thiobarbiturates; Trichloroethylene | 1986 |
Absorption, elimination and metabolism of trichloroethylene: a quantitative comparison between rats and mice.
Topics: Animals; Aroclors; Biotransformation; Cytochrome P-450 Enzyme System; Female; Intestinal Absorption; Liver; Mice; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Species Specificity; Trichloroethylene | 1986 |
Effects of ethanol and phenobarbital administration on the metabolism and toxicity of benzene.
Topics: Animals; Benzene; Cytochrome P-450 Enzyme System; Drug Interactions; Erythrocyte Count; Ethanol; Leukocyte Count; Male; Microsomes, Liver; Phenobarbital; Phenol; Phenols; Proteins; Rats; Rats, Inbred Strains; Toluene; Trichloroethylene | 1985 |
Proceedings: Kinetics of the binding of carbon monoxide and oxygen to microsomal cytochrome P450 and the influence of substrates.
Topics: Animals; Binding Sites; Carbon Monoxide; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Halothane; Hexobarbital; In Vitro Techniques; Kinetics; Ligands; Metyrapone; Microsomes, Liver; Oxygen Consumption; Phenobarbital; Photolysis; Rats; Spectrophotometry; Temperature; Tetrachloroethylene; Trichloroethylene | 1974 |
Enhancement of the hepatotoxicity of trichloroethylene by inducers of drug metabolism.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Drug Synergism; Glucose-6-Phosphatase; Liver; Male; Methylcholanthrene; Pharmaceutical Preparations; Phenobarbital; Rats; Time Factors; Trichloroethylene | 1974 |
Metabolism of trichloroethylene in liver microsomes. I. Characteristics of the reaction.
Topics: Animals; Chloral Hydrate; Chloromercuribenzoates; Cyanides; Dogs; Enzymes; Ethylmaleimide; Flavin Mononucleotide; Freeze Drying; In Vitro Techniques; Iodoacetates; Ions; Liver; Methylene Blue; Microsomes; NADP; Phenobarbital; Proadifen; Rabbits; Rats; Trichloroethylene; Vitamin K | 1965 |
Effects of metyrapone on liver microsomal drug oxidations.
Topics: Acetanilides; Aminopyrine; Animals; Depression, Chemical; Hexobarbital; In Vitro Techniques; Male; Metyrapone; Microsomes, Liver; Morphine; NADP; Phenobarbital; Rats; Sleep; Stimulation, Chemical; Trichloroethylene; Tyramine | 1969 |
Phenobarbital and organic solvent toxicity.
Topics: Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chloroform; Drug Synergism; Environmental Exposure; Ethane; Hydrocarbons, Chlorinated; Hydrocarbons, Halogenated; Injections, Intraperitoneal; Liver; Male; Methane; Methyl Chloride; Phenobarbital; Rats; Solvents; Tetrachloroethylene; Trichloroethylene | 1973 |
[Studies on the influence of inhalation anesthesia and surgery on liver function with special reference to halothane].
Topics: Anesthesia, Inhalation; Anesthetics; Animals; Chloroform; Enzyme Activation; Enzyme Induction; Halothane; Humans; Liver; Liver Diseases; Liver Function Tests; Phenobarbital; Rats; Sulfobromophthalein; Trichloroethylene | 1970 |
Metabolism of trichloroethylene in liver microsomes. 3. Induction of the enzymic activity and its effect on excretion of metabolites.
Topics: Alcohols; Animals; Enzyme Induction; Glucuronates; Liver; Male; Microsomes; Oxidoreductases; Phenobarbital; Rats; Trichloroacetic Acid; Trichloroethylene | 1967 |
Trichloroethylene effects on the formation of enzyme-altered foci in rat liver.
Topics: Animals; Diethylnitrosamine; Enzyme Induction; gamma-Glutamyltransferase; Hepatectomy; Liver; Liver Neoplasms, Experimental; Male; Phenobarbital; Rats; Rats, Inbred Strains; Trichloroethylene | 1984 |
Cardiac arrhythmogenic action of benzo(a)pyrene in the rabbit.
Topics: Animals; Arrhythmias, Cardiac; Benzo(a)pyrene; Benzopyrenes; Epinephrine; Ethylene Chlorohydrin; Halothane; Male; Methylcholanthrene; Phenobarbital; Rabbits; Time Factors; Trichloroacetic Acid; Trichloroethylene | 1983 |
Inhibition of delta-aminolevulinic acid dehydratase by trichloroethylene.
Topics: 5-Aminolevulinate Synthetase; Animals; Bone Marrow; Erythrocytes; Ethylene Chlorohydrin; In Vitro Techniques; Liver; Male; Phenobarbital; Porphobilinogen Synthase; Rats; Rats, Inbred Strains; Trichloroacetic Acid; Trichloroethanes; Trichloroethylene | 1984 |
Effect of tetrachloromethane and other chlorinated hydrocarbons on the hepatic metabolism in the isolated perfused rat liver.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chloroform; Hydrocarbons, Chlorinated; L-Iditol 2-Dehydrogenase; Liver; Male; Methylene Chloride; Phenobarbital; Rats; Rats, Inbred Strains; Trichloroethanes; Trichloroethylene | 1981 |
Metabolic activation and hepatotoxicity of trichloroethylene.
Topics: Animals; Aroclors; Aspartate Aminotransferases; Biotransformation; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Cytochromes; Cytochromes b5; Glutathione; Liver; NADH Dehydrogenase; Phenobarbital; Rats; Trichloroethylene | 1981 |
Metabolism of trichloroethylene.
Topics: Animals; Chloral Hydrate; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Phenobarbital; Proteins; Rats; Subcellular Fractions; Trichloroacetic Acid; Trichloroethylene | 1980 |
Optimization of an exogenous metabolic activation system for FETAX. I. Post-isolation rat liver microsome mixtures.
Topics: 2-Acetylaminofluorene; Abnormalities, Drug-Induced; Animals; beta-Naphthoflavone; Biotransformation; Chlorodiphenyl (54% Chlorine); Coumarins; Cyclophosphamide; Embryo, Mammalian; Embryo, Nonmammalian; Isoniazid; Microsomes, Liver; Phenobarbital; Rats; Toxicity Tests; Trichloroethylene; Xenopus laevis | 2001 |
THE RADIOGRAPHER AND THE ANAESTHETIST.
Topics: Amobarbital; Anesthesia; Anesthesia, Endotracheal; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthesia, Local; Anesthetics; Anesthetics, Local; Angiography; Cerebral Angiography; Equipment and Supplies; Halothane; Humans; Phenobarbital; Preanesthetic Medication; Radiography; Trichloroethylene | 1964 |
TRIGEMINAL NEURALGIA.
Topics: Atropa belladonna; Diagnosis; Drug Therapy; Geriatrics; Neurosurgery; Neurosurgical Procedures; Niacin; Nicotinic Acids; Parasympatholytics; Phenobarbital; Phenytoin; Thiamine; Trichloroethylene; Trigeminal Neuralgia | 1965 |