phenobarbital and transforming growth factor beta

phenobarbital has been researched along with transforming growth factor beta in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's19 (90.48)18.2507
2000's2 (9.52)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lu, B; Ogren, C; Roy, C; Roy, SK1
Michalopoulos, GK; Tsai, WH1
Michalopoulos, GK; Tsai, WH; Zarnegar, R1
Brockenbrough, JS; Jirtle, RL; Meyer, SA1
Jirtle, RL; Meyer, SA1
Andersen, ME; Greenlee, WF; Jirtle, RL; Mills, JJ1
Oberhammer, FA; Qin, HM1
Boyer, IJ; Hankins, GR; Jirtle, RL; Reisenbichler, H1
Stenius, U1
DeAngelo, AB; Tsai, WH1
Doughty, SE; Kalinowski, AE; Lord, PG; Orton, TC; Wadsworth, PF1
Fukushima, S; Funae, Y; Hagiwara, A; Ichihara, T; Imaoka, S; Kitano, M; Matsuda, T; Shirai, T; Tamano, S; Wanibuchi, H1
Cattley, RC; Christensen, JG; Goldsworthy, TL; Gonzales, AJ1
Alvarez, AM; Cascales, M; Díez-Fernández, C; Sanz, N; Wolf, A1
Klaassen, CD; Kolaja, KL1
Sanders, S; Thorgeirsson, SS1
Buchmann, A; Buenemann, CL; Schmiechen, A; Schwarz, M; Stroh, C; Willy, C1
Hood, AM; Klaassen, CD; Kolaja, KL1
Cattley, RC; Christensen, JG; Goldsworthy, TL1
Grasl-Kraupp, B; Hufnagl, K; Löw-Baselli, A; Parzefall, W; Schulte-Hermann, R1
Anzano, M; Factor, VM; Flanders, K; Hahm, KB; Haines, DC; Im, YH; Jang, JJ; Kim, HT; Kim, IY; Kim, SJ; Sizeland, A; Thorgeirsson, SS1

Reviews

2 review(s) available for phenobarbital and transforming growth factor beta

ArticleYear
Liver tumor promoter phenobarbital: a biphasic modulator of hepatocyte proliferation.
    Progress in clinical and biological research, 1991, Volume: 369

    Topics: Animals; Carcinogens; Cell Division; DNA Replication; Liver; Liver Neoplasms; Phenobarbital; Rats; Transforming Growth Factor beta

1991
Negative selection in hepatic tumor promotion in relation to cancer risk assessment.
    Toxicology, 1995, Sep-01, Volume: 102, Issue:1-2

    Topics: Animals; Carcinogens; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms, Experimental; Models, Biological; Phenobarbital; Polychlorinated Dibenzodioxins; Risk Assessment; Transforming Growth Factor beta

1995

Other Studies

19 other study(ies) available for phenobarbital and transforming growth factor beta

ArticleYear
Cell-type-specific localization of transforming growth factor-beta 2 and transforming growth factor-beta 1 in the hamster ovary: differential regulation by follicle-stimulating hormone and luteinizing hormone.
    Biology of reproduction, 1992, Volume: 46, Issue:4

    Topics: Animals; Blotting, Western; Cricetinae; Estrus; Female; Follicle Stimulating Hormone; Gene Expression Regulation; Hypophysectomy; Immunohistochemistry; Luteinizing Hormone; Ovary; Phenobarbital; Transforming Growth Factor beta

1992
Responsiveness of hepatocytes to epidermal growth factor, transforming growth factor-beta and norepinephrine during treatment with xenobiotic hepatic tumor promoters.
    Cancer letters, 1991, Volume: 57, Issue:1

    Topics: Animals; Carcinogens; Cells, Cultured; DNA Replication; Epidermal Growth Factor; Hexachlorocyclohexane; Kinetics; Liver; Male; Norepinephrine; Phenobarbital; Rats; Rats, Inbred F344; Transforming Growth Factor beta

1991
Long-term treatment with hepatic tumor promoters inhibits mitogenic responses of hepatocytes to acidic fibroblast growth factor and hepatocyte growth factor.
    Cancer letters, 1991, Volume: 59, Issue:2

    Topics: Animals; Carcinogens; Cells, Cultured; DNA; Fibroblast Growth Factor 1; Growth Substances; Hepatocyte Growth Factor; Hexachlorocyclohexane; Liver; Liver Regeneration; Male; Phenobarbital; Rats; Rats, Inbred F344; Thymidine; Transforming Growth Factor beta; Tritium

1991
Liver tumor promotion: effect of phenobarbital on EGF and protein kinase C signal transduction and transforming growth factor-beta 1 expression.
    Digestive diseases and sciences, 1991, Volume: 36, Issue:5

    Topics: Animals; Binding, Competitive; Cell Transformation, Neoplastic; Diethylnitrosamine; Epidermal Growth Factor; Liver; Liver Neoplasms, Experimental; Phenobarbital; Protein Kinase C; Rats; Signal Transduction; Transforming Growth Factor beta; Tumor Cells, Cultured

1991
Effect of three tumour promoters on the stability of hepatocyte cultures and apoptosis after transforming growth factor-beta 1.
    Carcinogenesis, 1995, Volume: 16, Issue:6

    Topics: Apoptosis; Carcinogens; Cell Differentiation; Cells, Cultured; Cyproterone Acetate; Epidermal Growth Factor; In Vitro Techniques; Liver; Nafenopin; Phenobarbital; Proliferating Cell Nuclear Antigen; Time Factors; Transforming Growth Factor beta

1995
Regulation of mannose 6-phosphate/insulin-like growth factor-II receptors and transforming growth factor beta during liver tumor promotion with phenobarbital.
    Carcinogenesis, 1994, Volume: 15, Issue:8

    Topics: Animals; Liver; Liver Neoplasms, Experimental; Male; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred F344; Receptor, IGF Type 2; RNA, Messenger; Transforming Growth Factor beta

1994
Different inhibition of DNA synthesis by transforming growth factor beta and phenobarbital on GST-P-positive and GST-P-negative hepatocytes.
    Carcinogenesis, 1993, Volume: 14, Issue:1

    Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Diethylnitrosamine; DNA; Female; Glutathione Transferase; Liver; Phenobarbital; Rats; Transforming Growth Factor beta

1993
Responsiveness of hepatocytes from dichloroacetic acid or phenobarbital treated mice to growth factors in primary culture.
    Cancer letters, 1996, Feb-06, Volume: 99, Issue:2

    Topics: Animals; Cells, Cultured; Dichloroacetic Acid; DNA; Dose-Response Relationship, Drug; Drug Interactions; Epidermal Growth Factor; Fibroblast Growth Factor 1; Growth Substances; Hepatocyte Growth Factor; Kinetics; Liver; Male; Mice; Mice, Inbred Strains; Phenobarbital; Thymidine; Transforming Growth Factor beta

1996
Expression of growth factors and growth factor receptors in the liver of C57BL/10J mice following administration of phenobarbitone.
    Carcinogenesis, 1996, Volume: 17, Issue:5

    Topics: Animals; Carcinogens; Cell Division; Dose-Response Relationship, Drug; ErbB Receptors; Growth Substances; Hepatocyte Growth Factor; Immunohistochemistry; Liver; Male; Mice; Mice, Inbred C57BL; Organ Size; Phenobarbital; Proto-Oncogene Proteins c-met; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Transforming Growth Factor beta

1996
Presence of a threshold for promoting effects of phenobarbital on diethylnitrosamine-induced hepatic foci in the rat.
    Carcinogenesis, 1998, Volume: 19, Issue:8

    Topics: Animals; Carcinogens; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Dose-Response Relationship, Drug; Glutathione Transferase; Hepatectomy; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Phenobarbital; Rats; Rats, Inbred F344; Transforming Growth Factor alpha; Transforming Growth Factor beta

1998
Regulation of apoptosis in mouse hepatocytes and alteration of apoptosis by nongenotoxic carcinogens.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1998, Volume: 9, Issue:9

    Topics: Animals; Anti-Bacterial Agents; Apoptosis; Bleomycin; Carcinogens; Cells, Cultured; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Nafenopin; Phenobarbital; Proto-Oncogene Proteins c-bcl-2; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Transforming Growth Factor beta; Tumor Suppressor Protein p53

1998
The effect of non-genotoxic carcinogens, phenobarbital and clofibrate, on the relationship between reactive oxygen species, antioxidant enzyme expression and apoptosis.
    Carcinogenesis, 1998, Volume: 19, Issue:10

    Topics: Animals; Apoptosis; Carcinogens; Catalase; Cells, Cultured; Clofibrate; Gene Expression Regulation, Enzymologic; Liver; Male; Peroxides; Phenobarbital; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Transforming Growth Factor beta

1998
Dose-response examination of UDP-glucuronosyltransferase inducers and their ability to increase both TGF-beta expression and thyroid follicular cell apoptosis.
    Toxicological sciences : an official journal of the Society of Toxicology, 1998, Volume: 46, Issue:1

    Topics: Animals; Apoptosis; Chlorodiphenyl (54% Chlorine); Dose-Response Relationship, Drug; Enzyme Induction; Glucuronosyltransferase; Immunohistochemistry; Male; Methylcholanthrene; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Thyroid Gland; Transforming Growth Factor beta

1998
Phenobarbital promotes liver growth in c-myc/TGF-alpha transgenic mice by inducing hypertrophy and inhibiting apoptosis.
    Carcinogenesis, 1999, Volume: 20, Issue:1

    Topics: Animals; Apoptosis; bcl-X Protein; Carcinogens; Cell Division; Diet; Gene Expression Regulation; Genes, bcl-2; Genes, myc; Hypertrophy; Liver; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Organ Size; Phenobarbital; Proto-Oncogene Proteins c-bcl-2; Receptors, Growth Factor; Transforming Growth Factor alpha; Transforming Growth Factor beta

1999
Inhibition of transforming growth factor beta1-induced hepatoma cell apoptosis by liver tumor promoters: characterization of primary signaling events and effects on CPP32-like caspase activity.
    Cell death and differentiation, 1999, Volume: 6, Issue:2

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Calcium-Calmodulin-Dependent Protein Kinases; Caspase 3; Caspases; Clofibrate; DDT; Dexamethasone; Dieldrin; Insulin; Liver Neoplasms, Experimental; NF-kappa B; Phenobarbital; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Signal Transduction; Time Factors; Transforming Growth Factor beta; Tumor Cells, Cultured

1999
The UDP-glucuronyltransferase inducers, phenobarbital and pregnenolone-16alpha-carbonitrile, enhance thyroid-follicular cell apoptosis: association with TGF-beta1 expression.
    Toxicology letters, 1999, Jun-01, Volume: 106, Issue:2-3

    Topics: Animals; Apoptosis; Enzyme Induction; Glucuronosyltransferase; Hyperplasia; Male; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Thyroid Gland; Transforming Growth Factor beta

1999
Dysregulation of apoptosis by c-myc in transgenic hepatocytes and effects of growth factors and nongenotoxic carcinogens.
    Molecular carcinogenesis, 1999, Volume: 25, Issue:4

    Topics: Animals; Animals, Genetically Modified; Apoptosis; Bleomycin; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Genes, myc; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Phenobarbital; Proto-Oncogene Mas; Proto-Oncogene Proteins c-bcl-2; Transforming Growth Factor alpha; Transforming Growth Factor beta; Tumor Suppressor Protein p53

1999
Initiated rat hepatocytes in primary culture: a novel tool to study alterations in growth control during the first stage of carcinogenesis.
    Carcinogenesis, 2000, Volume: 21, Issue:1

    Topics: Animals; Cell Division; Cells, Cultured; Cyproterone Acetate; DNA; Glutathione Transferase; Liver; Liver Neoplasms; Male; Nitrosamines; Phenobarbital; Phenotype; Precancerous Conditions; Rats; Rats, Wistar; Transforming Growth Factor beta

2000
Heterozygous mice for the transforming growth factor-beta type II receptor gene have increased susceptibility to hepatocellular carcinogenesis.
    Cancer research, 2001, Sep-15, Volume: 61, Issue:18

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Diethylnitrosamine; Female; Gene Dosage; Genes, cdc; Genetic Predisposition to Disease; Heterozygote; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Phenobarbital; Pregnancy; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1

2001