phenobarbital has been researched along with transforming growth factor alpha in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (70.59) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Manjeshwar, S; Rajalakshmi, S; Rao, PM; Sarma, DS | 1 |
| Aubrecht, J; Becker-Rabbenstein, V; Hirsch-Ernst, KI; Höhne, MW; Kahl, GF; Taniguchi, H | 1 |
| Merlino, GT; Tamano, S; Ward, JM | 1 |
| Laconi, E; Manjeshwar, S; Rajalakshmi, S; Rao, PM; Sarma, DS | 1 |
| Santoni-Rugiu, E; Thorgeirsson, SS | 2 |
| Davis, CD; Santoni-Rugiu, E; Snyderwine, EG; Thorgeirsson, SS | 1 |
| Byrd, LL; Kaufmann, WK; Nims, RW; Palmieri, D; Rice, JM | 1 |
| Fujiwara, K; Ogata, I; Tomiya, T | 1 |
| Fukushima, S; Funae, Y; Hagiwara, A; Ichihara, T; Imaoka, S; Kitano, M; Matsuda, T; Shirai, T; Tamano, S; Wanibuchi, H | 1 |
| Sanders, S; Thorgeirsson, SS | 2 |
| Cattley, RC; Christensen, JG; Goldsworthy, TL | 1 |
| Betton, G; Gould, S; Orton, T; Sansom, N; Sidaway, J | 1 |
| Chabicovsky, M; Grasl-Kraupp, B; Peter, B; Rossmanith, W; Schausberger, E; Schulte-Hermann, R | 1 |
| Calvisi, DF; Factor, VM; Ladu, S; Thorgeirsson, SS | 1 |
| Ariki, Y; Fukushima, S; Hidaka, T; Hosoe, K; Kato, M; Kitano, M; Morimura, K; Wada, J; Wanibuchi, H | 1 |
17 other study(ies) available for phenobarbital and transforming growth factor alpha
| Article | Year |
|---|---|
Inhibition of DNA synthesis by phenobarbital in primary cultures of hepatocytes from normal rat liver and from hepatic nodules.
Topics: Animals; Carcinogens; Cells, Cultured; DNA Replication; Epidermal Growth Factor; ErbB Receptors; Liver; Liver Diseases; Male; Orotic Acid; Phenobarbital; Rats; Rats, Inbred F344; Transforming Growth Factor alpha | 1992 |
Induction of cytochrome P-4502B1-related mouse cytochrome P-450 and regulation of its expression by epidermal growth factor/transforming growth factor alpha in primary hepatocyte culture.
Topics: Animals; Antibodies, Monoclonal; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Enzyme Induction; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Liver; Male; Mice; Mice, Inbred C57BL; Oxidoreductases; Phenobarbital; Rats; Rats, Wistar; RNA, Messenger; Steroid Hydroxylases; Time Factors; Transforming Growth Factor alpha | 1995 |
Rapid development of hepatic tumors in transforming growth factor alpha transgenic mice associated with increased cell proliferation in precancerous hepatocellular lesions initiated by N-nitrosodiethylamine and promoted by phenobarbital.
Topics: Animals; Body Weight; Cell Division; Cocarcinogenesis; Diethylnitrosamine; Gene Expression; Immunohistochemistry; Liver Neoplasms, Experimental; Male; Mice; Mice, Transgenic; Phenobarbital; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Transforming Growth Factor alpha | 1994 |
Influence of orotic acid on multistage hepatocarcinogenesis in the rat: resistance of hepatocytes from nodules to the mitoinhibitory effects of orotic acid.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Cells, Cultured; Dimethylhydrazines; DNA; DNA Replication; Liver; Liver Neoplasms, Experimental; Male; Mitosis; Orotic Acid; Phenobarbital; Rats; Rats, Inbred F344; Transforming Growth Factor alpha | 1993 |
Transgenic mouse models in carcinogenesis: interaction of c-myc with transforming growth factor alpha and hepatocyte growth factor in hepatocarcinogenesis.
Topics: Albumins; Animals; Disease Models, Animal; Female; Genes, myc; Hepatocyte Growth Factor; Liver Neoplasms, Experimental; Metallothionein; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Phenobarbital; Transforming Growth Factor alpha | 1996 |
Hepatic tumor induction in c-myc mono-transgenic and TGF-alpha/c-myc double-transgenic mice.
Topics: Animals; Carcinogens; Diethylnitrosamine; Liver Neoplasms, Experimental; Mice; Mice, Transgenic; Phenobarbital; Proto-Oncogene Proteins c-myc; Quinolines; Transforming Growth Factor alpha | 1997 |
Interaction of c-myc with transforming growth factor alpha and hepatocyte growth factor in hepatocarcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Gene Expression; Gene Expression Regulation, Neoplastic; Hepatocyte Growth Factor; Liver Neoplasms; Liver Neoplasms, Experimental; Mice; Mice, Transgenic; Neoplasms, Experimental; Phenobarbital; Proto-Oncogene Proteins c-myc; Transforming Growth Factor alpha | 1997 |
TGF-alpha sustains clonal expansion by promoter-dependent, chemically initiated rat hepatocytes.
Topics: Animals; Carcinogens; Cell Division; Cell Line; Dose-Response Relationship, Drug; Liver; Liver Neoplasms, Experimental; Phenobarbital; Rats; Transforming Growth Factor alpha | 1997 |
Transforming growth factor alpha levels in liver and blood correlate better than hepatocyte growth factor with hepatocyte proliferation during liver regeneration.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Cell Division; Dimethylnitrosamine; Disease Models, Animal; Hepatocyte Growth Factor; Liver; Liver Regeneration; Male; Mitotic Index; Necrosis; Phenobarbital; Rats; Rats, Sprague-Dawley; Transforming Growth Factor alpha | 1998 |
Presence of a threshold for promoting effects of phenobarbital on diethylnitrosamine-induced hepatic foci in the rat.
Topics: Animals; Carcinogens; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Dose-Response Relationship, Drug; Glutathione Transferase; Hepatectomy; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Phenobarbital; Rats; Rats, Inbred F344; Transforming Growth Factor alpha; Transforming Growth Factor beta | 1998 |
Phenobarbital promotes liver growth in c-myc/TGF-alpha transgenic mice by inducing hypertrophy and inhibiting apoptosis.
Topics: Animals; Apoptosis; bcl-X Protein; Carcinogens; Cell Division; Diet; Gene Expression Regulation; Genes, bcl-2; Genes, myc; Hypertrophy; Liver; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Organ Size; Phenobarbital; Proto-Oncogene Proteins c-bcl-2; Receptors, Growth Factor; Transforming Growth Factor alpha; Transforming Growth Factor beta | 1999 |
Dysregulation of apoptosis by c-myc in transgenic hepatocytes and effects of growth factors and nongenotoxic carcinogens.
Topics: Animals; Animals, Genetically Modified; Apoptosis; Bleomycin; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Genes, myc; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Phenobarbital; Proto-Oncogene Mas; Proto-Oncogene Proteins c-bcl-2; Transforming Growth Factor alpha; Transforming Growth Factor beta; Tumor Suppressor Protein p53 | 1999 |
Promotion of hepatocarcinogenesis by phenobarbital in c-myc/TGF-alpha transgenic mice.
Topics: Animals; Apoptosis; bcl-X Protein; Carcinogens; Cell Transformation, Neoplastic; Crosses, Genetic; Genes, myc; Genes, Synthetic; Genetic Predisposition to Disease; Humans; Liver Neoplasms, Experimental; Metallothionein; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Neoplasm Proteins; Phenobarbital; Precancerous Conditions; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Transforming Growth Factor alpha; Transgenes | 2000 |
Phenobarbitone-induced liver response in wild type and in p53 deficient mice.
Topics: Animals; ErbB Receptors; Immunohistochemistry; Liver; Male; Mice; Mice, Inbred C57BL; Organ Size; Phenobarbital; Transforming Growth Factor alpha; Tumor Suppressor Protein p53 | 2001 |
Follistatin overexpression in rodent liver tumors: a possible mechanism to overcome activin growth control.
Topics: Activins; Adenoma; Alternative Splicing; Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Division; Diethylnitrosamine; Follistatin; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred Strains; Nafenopin; Phenobarbital; Rats; Reference Values; RNA, Messenger; Transforming Growth Factor alpha; Tumor Cells, Cultured | 2002 |
Activation of beta-catenin provides proliferative and invasive advantages in c-myc/TGF-alpha hepatocarcinogenesis promoted by phenobarbital.
Topics: Animals; Apoptosis; Base Sequence; beta Catenin; Cell Division; Cytoskeletal Proteins; DNA Primers; Immunohistochemistry; Liver Neoplasms, Experimental; Loss of Heterozygosity; Mice; Mice, Transgenic; Neoplasm Invasiveness; Phenobarbital; Proto-Oncogene Proteins c-myc; Trans-Activators; Transforming Growth Factor alpha | 2004 |
Possible tumor development from double positive foci for TGF-alpha and GST-P observed in early stages on rat hepatocarcinogenesis.
Topics: Animals; Carcinogenicity Tests; Carcinogens; Diethylnitrosamine; Glutathione S-Transferase pi; Hepatectomy; Immunohistochemistry; Liver Neoplasms, Experimental; Male; Phenobarbital; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Transforming Growth Factor alpha | 2006 |