phenobarbital has been researched along with toluene in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (60.53) | 18.7374 |
| 1990's | 11 (28.95) | 18.2507 |
| 2000's | 4 (10.53) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duffy, EM; Jorgensen, WL | 1 |
| Caron, G; Ermondi, G | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Abellán Guillén, A; Cordeiro, MN; Garrido Escudero, A; Morales Helguera, A; Pérez-Garrido, A | 1 |
| Dacre, JC; Lee, CC; Short, RD | 1 |
| Georgiev, VP; Petkova, BP | 1 |
| Gangolli, SD; Hodgson, RA; Lake, BG; Lloyd, AG; Longland, RC; Severn, BJ | 1 |
| Galdhar, NR; Mungikar, AM; Pawar, SS | 1 |
| Mungikar, AM; Pawar, SS | 1 |
| Makhija, SJ; Mungikar, AM; Pawar, SS | 1 |
| Nakajima, T; Wang, RS | 2 |
| Elovaara, E; Gelboin, HV; Nakajima, T; Park, SS; Vainio, H; Wang, RS | 1 |
| Gordon, R; Kassay, K; Kuiper, H; Pryor, G; Rebert, C | 1 |
| Elovaara, E; Gelboin, HV; Hietanen, E; Nakajima, T; Park, SS; Vainio, H; Wang, RS | 1 |
| Nakaoka, M | 1 |
| Chism, JP; Kedderis, GL; Rickert, DE | 1 |
| Barcza, G; Marton, J; Szeberényi, S; Ungváry, G | 1 |
| Nakajima, T; Okuyama, S; Sato, A; Yonekura, I | 1 |
| Eulenstedt, C; Koransky, W; Leberl, C; Schlicht, I; Schulte-Hermann, R; Zimek, M | 1 |
| Feuer, G; Granda, V | 1 |
| Ikeda, M; Imamura, T; Otsuji, H | 2 |
| Ikeda, M; Otsuji, H | 1 |
| Magour, S; Nievel, JG | 1 |
| Akagi, M; Suga, T | 1 |
| DeCarli, LM; Lieber, CS | 1 |
| Marchand, C; McLean, S; Plaa, GL | 1 |
| Gad-El-Karim, MM; Harper, BL; Legator, MS | 1 |
| Aristov, VN; Gichev, IuP; Red'kin, IuV; Taskaev, II | 1 |
| Pyykkö, K | 1 |
| Brugnone, F; Fracasso, ME; Leone, R; Perbellini, L; Venturini, MS | 1 |
| Blake, RC; Coon, MJ | 1 |
| Aoyama, T; Elovaara, E; Gelboin, HV; Klockars, M; Nakajima, T; Okino, T; Riihimäki, V; Vainio, H | 1 |
| Bondy, SC; Naderi, S | 1 |
| Baker, MT; Chadam, MV; Ronnenberg, WC | 1 |
| Ripel, A; Smith-Kielland, A | 1 |
| Løkken, T; Mortensen, B; Nilsen, OG; Zahlsen, K | 1 |
38 other study(ies) available for phenobarbital and toluene
| Article | Year |
|---|---|
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins.
Topics: beta-Cyclodextrins; Hydrophobic and Hydrophilic Interactions; Organic Chemicals; Quantitative Structure-Activity Relationship | 2009 |
A species comparison of 2,4-dinitrotoluene metabolism in vitro.
Topics: Animals; Carbon Radioisotopes; Dinitrobenzenes; Dogs; Female; Haplorhini; Liver; Macaca mulatta; Male; Nitro Compounds; Phenobarbital; Proadifen; Rabbits; Sex Factors; Species Specificity; Toluene | 1979 |
Effect of p-chlorophenylalanine on the central nervous excitability threshold and on the activity of some central depressants.
Topics: Animals; Central Nervous System; Depression, Chemical; Fenclonine; Hypnotics and Sedatives; Injections, Intraperitoneal; Injections, Intravenous; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenylacetates; Picrotoxin; Seizures; Strychnine; Time Factors; Toluene; Urea | 1975 |
The effect of some inducers of hepatic xenobiotic-metabolizing enzymes on the urinary excretion of D-glucuronic acid metabolites in the rat.
Topics: Aniline Hydroxylase; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethylmorphine-N-Demethylase; Glucuronates; Glucuronosyltransferase; Hymecromone; Insecticides; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Pregnenolone; Rats; Time Factors; Toluene | 1975 |
Influence of phenobarbital and 3-methylcholanthrene pretreatment on kidney microsomal mixed function oxidase system during benzene and toluene intoxication in adult male rats.
Topics: Animals; Benzene; Depression, Chemical; Kidney; Male; Methylcholanthrene; Microsomes; Oxidoreductases; Phenobarbital; Rats; Toluene | 1975 |
Hepatic microsomal mixed function oxidase system during toluene treatment and the effect of pretreatment of phenobarbital in adult rats.
Topics: Animals; Electron Transport; Male; Microsomes, Liver; Mixed Function Oxygenases; Organ Size; Oxidoreductases; Phenobarbital; Proteins; Rats; Toluene | 1976 |
Phenobarbital induced effect on pulmonary and hepatic microsomal ethylmorphine N-demethylase and lipid peroxidation during oral intoxication of organic solvents in rats.
Topics: Animals; Benzene; Ethylmorphine-N-Demethylase; In Vitro Techniques; Lipid Metabolism; Lung; Male; Microsomes; Microsomes, Liver; Oxidoreductases, N-Demethylating; Peroxides; Phenobarbital; Rats; Toluene | 1976 |
Effects of ethanol and phenobarbital treatments on the pharmacokinetics of toluene in rats.
Topics: Animals; Benzoates; Benzoic Acid; Cresols; Cytochrome P-450 Enzyme System; Ethanol; Glucuronates; Glucuronic Acid; Hippurates; Male; Metabolic Clearance Rate; Phenobarbital; Rats; Rats, Inbred Strains; Toluene | 1992 |
A comparative study on the contribution of cytochrome P450 isozymes to metabolism of benzene, toluene and trichloroethylene in rat liver.
Topics: Animals; Antibodies, Monoclonal; Benzene; Chloral Hydrate; Cytochrome P-450 Enzyme System; Ethanol; Isoenzymes; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains; Substrate Specificity; Toluene; Trichloroethylene | 1992 |
The hearing loss associated with exposure to toluene is not caused by a metabolite.
Topics: Acoustic Stimulation; Animals; Auditory Perception; Biotransformation; Drinking Behavior; Hearing; Hearing Loss; Hippurates; Male; Phenobarbital; Rats; Rats, Inbred F344; Toluene | 1991 |
Monoclonal antibody-directed characterization of cytochrome P450 isozymes responsible for toluene metabolism in rat liver.
Topics: Animals; Antibodies, Monoclonal; Benzyl Alcohol; Benzyl Alcohols; Cresols; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ethanol; Isoenzymes; Kinetics; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Toluene | 1991 |
Kinetic studies on toluene metabolism in ethanol- and phenobarbital-induced rat liver microsomes in vitro.
Topics: Animals; Benzyl Alcohols; Cresols; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Ethanol; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Toluene | 1991 |
Kinetic characteristics of UDP-glucuronosyltransferases towards a dithiol metabolite of malotilate in hepatic microsomes of rats and rabbits.
Topics: Animals; Enzyme Induction; Glucuronosyltransferase; Hydrogen-Ion Concentration; Kinetics; Male; Malonates; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rabbits; Rats; Rats, Inbred Strains; Toluene | 1990 |
Metabolism and carcinogenicity of nitrotoluenes.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Bile; Biotransformation; Carcinogens; Female; Gallbladder; Liver; Male; Microsomes, Liver; Phenobarbital; Rats; Sex Factors; Toluene | 1986 |
Inducibility of the hepatic microsomal monooxygenase system experimentally reduced to a minimum amount/activity. Effect of hypophysectomy, partial hepatectomy and phenobarbital/toluene treatment on the hepatic polysubstrate monooxygenase system in rats.
Topics: Animals; Enzyme Induction; Hepatectomy; Hypophysectomy; Male; Microscopy, Electron; Microsomes, Liver; Mitotic Index; Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains; Toluene | 1985 |
Effects of ethanol and phenobarbital administration on the metabolism and toxicity of benzene.
Topics: Animals; Benzene; Cytochrome P-450 Enzyme System; Drug Interactions; Erythrocyte Count; Ethanol; Leukocyte Count; Male; Microsomes, Liver; Phenobarbital; Phenol; Phenols; Proteins; Rats; Rats, Inbred Strains; Toluene; Trichloroethylene | 1985 |
Selective inhibition of liver-cell proliferation by CFT 1201 and SKF 525 A. Studies on growth processes induced by drugs and by partial hepatectomy.
Topics: Acetamides; Animals; DNA; Female; Hepatectomy; Hexachlorocyclohexane; Liver; Microsomes, Liver; Mitosis; Organ Size; Oxidoreductases; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Stimulation, Chemical; Sulfur; Thymidine; Toluene; Tritium | 1972 |
Antagonistic effect of foreign compounds on microsomal enzymes of the liver of the rat.
Topics: Acetates; Amides; Animals; Carbon Tetrachloride; Coumarins; Drug Antagonism; Enzymes; Ethionine; Female; Hexobarbital; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Phosphoric Monoester Hydrolases; Rats; Toluene | 1970 |
Comparative studies on aniline hydroxylation and p-nitrotoluene hydroxylation by the liver.
Topics: Acetamides; Acetone; Aniline Compounds; Animals; Biotransformation; Cricetinae; Depression, Chemical; Guinea Pigs; Hydroxylation; Kinetics; Liver; Methylcholanthrene; Metyrapone; Mice; Phenobarbital; Pyridines; Rabbits; Rats; Sex Factors; Stimulation, Chemical; Toluene | 1972 |
In vivo suppression of benzene and styrene oxidation by co-administered toluene in rats and effects of phenobarbital.
Topics: Animals; Benzene; Biotransformation; Drug Interactions; Female; Glyoxylates; Hippurates; Kinetics; Mandelic Acids; Oxidation-Reduction; Phenobarbital; Rats; Rats, Inbred Strains; Styrenes; Toluene | 1972 |
Phenobarbital-induced protection against toxicity of toluene and benzene in the rat.
Topics: Animals; Benzene; Benzoates; Chromatography, Paper; Chromatography, Thin Layer; Female; Glucuronates; Guinea Pigs; Hexosyltransferases; Hippurates; Lethal Dose 50; Leukopenia; Liver; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Phenols; Poisoning; Rats; Rats, Inbred Strains; Time Factors; Toluene | 1971 |
Effect of inducers of drug-metabolizing enzymes on diethylnitrosamine metabolism and toxicity.
Topics: Animals; DDT; Enzyme Induction; Female; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Phenobarbital; Rats; Toluene | 1971 |
Studies on mercapturic acids. Effect of some chemical compounds on the activities of glutathione-conjugating enzymes.
Topics: Animals; Benzene Derivatives; Female; Glutathione; In Vitro Techniques; Ligases; Liver; Microsomes, Liver; Mixed Function Oxygenases; Nitrobenzenes; Phenobarbital; Rats; Toluene | 1970 |
Effect of drug administration on the activity of the hepatic microsomal ethanol oxidizing system.
Topics: Alcohol Oxidoreductases; Animals; Catalase; Ethanol; Female; Liver; Male; Methylcholanthrene; Microsomes, Liver; Organ Size; Oxidation-Reduction; Phenobarbital; Proteins; Rats; Toluene; Triazoles | 1970 |
The effect of SKF 525A on the distribution of carbon tetrachloride in rats.
Topics: Adipose Tissue; Administration, Oral; Animals; Brain Chemistry; Carbon Isotopes; Carbon Tetrachloride; Injections, Intraperitoneal; Injections, Subcutaneous; Intestinal Absorption; Liver; Male; Muscles; Phenobarbital; Proadifen; Rats; Solubility; Time Factors; Toluene | 1970 |
Modifications in the myeloclastogenic effect of benzene in mice with toluene, phenobarbital, 3-methylcholanthrene, Aroclor 1254 and SKF-525A.
Topics: Animals; Aroclors; Benzene; Bone Marrow; Cell Nucleus; Chlorodiphenyl (54% Chlorine); Drug Interactions; Female; Male; Metaphase; Methylcholanthrene; Mice; Mutagenicity Tests; Mutagens; Mutation; Phenobarbital; Polychlorinated Biphenyls; Proadifen; Sex Factors; Toluene | 1984 |
[Study of the protective effects of phenobarbital and aminopyrine in a toxicologic experiment].
Topics: 1-Propanol; Aminopyrine; Animals; Biotransformation; Liver; Male; Phenobarbital; Rats; Sulfur Dioxide; Toluene | 1983 |
Effects of pretreatment with toluene, phenobarbital and 3-methylcholantrene on the in vivo metabolism of toluene and on the excretion of hippuric acid in the rat.
Topics: Animals; Benzoates; Benzoic Acid; Chromatography, Gas; Chromatography, High Pressure Liquid; Enzyme Induction; Hippurates; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains; Toluene | 1984 |
Metabolic interaction between n-hexane and toluene in vivo and in vitro.
Topics: Animals; Biotransformation; Drug Interactions; Hexanes; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Phenobarbital; Premedication; Rats; Rats, Inbred Strains; Toluene | 1982 |
On the mechanism of action of cytochrome P-450. Role of peroxy spectral intermediates in substrate hydroxylation.
Topics: Animals; Benzyl Alcohols; Cytochrome P-450 Enzyme System; Kinetics; Microsomes, Liver; Phenobarbital; Protein Binding; Rabbits; Spectrophotometry; Toluene | 1981 |
Different contributions of cytochrome P450 2E1 and P450 2B1/2 to chloroform hepatotoxicity in rat.
Topics: Alanine Transaminase; Animals; Antibodies, Monoclonal; Antibody Formation; Aryl Hydrocarbon Hydroxylases; Benzyl Alcohol; Benzyl Alcohols; Body Weight; Chloroform; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Hexanes; Immunoblotting; Liver; Male; Methyl n-Butyl Ketone; Microsomes, Liver; Organ Size; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Rats, Wistar; Steroid Hydroxylases; Toluene | 1995 |
Contribution of hepatic cytochrome P450 systems to the generation of reactive oxygen species.
Topics: Animals; Catalase; Cytochrome P-450 Enzyme System; Ethanol; Glutathione Peroxidase; Male; Microsomes, Liver; NADP; Pentetic Acid; Phenobarbital; Proadifen; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Toluene | 1994 |
Inhibitory effects of propofol on cytochrome P450 activities in rat hepatic microsomes.
Topics: Aniline Compounds; Animals; Benzphetamine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enflurane; Hydroxylation; Isoniazid; Male; Methylation; Microsomes, Liver; Phenobarbital; Propofol; Rats; Rats, Sprague-Dawley; Toluene | 1993 |
Toluene metabolism in isolated rat hepatocytes: effects of in vivo pretreatment with acetone and phenobarbital.
Topics: Acetone; Animals; Benzaldehydes; Benzoates; Benzoic Acid; Benzyl Alcohol; Benzyl Alcohols; Binding, Competitive; Cell Survival; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Glycine; Hippurates; Isoenzymes; Kinetics; Liver; Male; Oxidation-Reduction; Phenobarbital; Rats; Rats, Wistar; Toluene | 1993 |
Comparison and in vivo relevance of two different in vitro head space metabolic systems: liver S9 and liver slices.
Topics: Acetone; Animals; Benzoates; Benzoic Acid; Biotransformation; Chelating Agents; Ditiocarb; Hexanes; Hexanols; Hexanones; Hippurates; Hypnotics and Sedatives; In Vitro Techniques; Liver; Male; Phenobarbital; Rats; Rats, Sprague-Dawley; Solvents; Toluene | 1997 |