phenobarbital and tolbutamide

phenobarbital has been researched along with tolbutamide in 60 studies

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-199043 (71.67)18.7374
1990's2 (3.33)18.2507
2000's8 (13.33)29.6817
2010's7 (11.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Carrupt, PA; Martel, S; Ottaviani, G1
Abraham, MH; Acree, WE; Ibrahim, A1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bending, MR; Dollery, CT; Kahn, GC; Mucklow, JC1
Müller-Oerlinghausen, B1
Henderson, AD; Poffenbarger, PL; Scott, J1
Mennear, JH; Schonwalder, C; Yau, ET1
Assandri, A; Perazzi, A1
Carulli, N; Ferrari, A; Manenti, F; Mauro, E; Ponz de Leon, M1
Reidenberg, MM1
Braun, W; Koslowski, H; Menzel, K1
Bélanger, PM; St-Hilaire, S1
Houston, JB; Matthew, DE1
Welch, RM1
Remmer, H1
Ernzerhoff, C; Holtz, P; Palm, D2
De Matteis, F2
Gerhards, E; Kolb, KH; Schulze, PE1
Ikeda, M; Imamura, T; Otsuji, H1
Kamath, C; Nayak, SV; Salomon, MI; Tchertkoff, V1
Kamegaya, K; Oda, M; Okazaki, I; Sanbe, K1
Darby, FJ1
Prescott, LF; Redman, DR1
Darby, J1
Hirayama, C; Kawasaki, H; Oma, H; Sakaguchi, S; Tominaga, K1
Gastol-Lewińska, L1
Aggarwal, V; Sunshine, I1
Chalabala, M; Lichnerová, I1
Stenger, RJ1
Hirayama, C1
Ichibagase, H; Inoue, K; Kojima, S; Suenaga, A1
Abrams, WB; Reich, S; Solomon, HM; Spirt, N1
Calhoun, FJ; Schrogie, JJ; Tolson, WW1
Amagase, H; Hirayama, C; Irisa, T; Kawasaki, H; Sakai, K1
Brody, BB1
Duckert, F; Seiler, K1
Dibbern, HW1
Airth, JM; Bray, DF; Radecka, C1
Globus, M; McColl, JD; Robinson, S1
Back, DJ; Sutcliffe, F; Tjia, JF1
Goldberg, DM1
MERKER, HJ; REMMER, H2
BURNS, JJ1
EICH, WF; FUJIMOTO, JM; NICHOLS, HR1
Endo, S; Ikari, A; Matsunaga, T; Miyagi, N1

Reviews

10 review(s) available for phenobarbital and tolbutamide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug metabolism in uremia.
    Clinical nephrology, 1975, Volume: 4, Issue:3

    Topics: Acetohexamide; Animals; Antipyrine; Humans; Hydrolysis; Lipid Metabolism; Microsomes, Liver; Oxidation-Reduction; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Procainamide; Rats; Tolbutamide; Uremia; Vitamin D

1975
Toxic hepatic porphyrias.
    Seminars in hematology, 1968, Volume: 5, Issue:4

    Topics: Alcoholism; Antifungal Agents; Chemical and Drug Induced Liver Injury; Chlorpropamide; Hexachlorocyclohexane; Humans; Liver; Phenobarbital; Phenytoin; Porphyrias; Sulfanilamides; Sulfones; Tolbutamide; Turkey

1968
[Advances in the treatment of jaundice in the department of internal medicine].
    Nihon rinsho. Japanese journal of clinical medicine, 1972, Volume: 30, Issue:9

    Topics: Adrenal Cortex Hormones; Adult; Bilirubin; Cholestasis; Female; Humans; Hyperbilirubinemia; Jaundice; Phenobarbital; Tolbutamide

1972
Disturbances of liver porphyrin metabolism caused by drugs.
    Pharmacological reviews, 1967, Volume: 19, Issue:4

    Topics: Animals; Chlorpropamide; Drug-Related Side Effects and Adverse Reactions; Estrogens; Griseofulvin; Humans; Hypnotics and Sedatives; Liver; Mice; Phenobarbital; Porphyrias; Porphyrins; Rats; Sulfones; Tolbutamide

1967
[Drugs for rectal application. IV. Absorption of rectally administered drugs].
    Ceskoslovenska farmacie, 1969, Volume: 18, Issue:9

    Topics: Aminohippuric Acids; Aminosalicylic Acids; Aspirin; Emulsions; Hexobarbital; Intestinal Absorption; Lipids; Penicillins; Pharmaceutic Aids; Pharmaceutical Preparations; Phenobarbital; Rectum; Sodium; Solubility; Solvents; Sulfisomidine; Suppositories; Thiopental; Tolbutamide; Water

1969
Organelle pathology of the liver. The endoplasmic reticulum.
    Gastroenterology, 1970, Volume: 58, Issue:4

    Topics: Animals; Chlordan; DDT; Endoplasmic Reticulum; Ethanol; Glycogen; Lipid Metabolism; Liver; Liver Diseases; Necrosis; Nikethamide; Phenobarbital; Protein Biosynthesis; Rats; Tolbutamide

1970
[Enzyme induction therapy of liver diseases].
    Nihon rinsho. Japanese journal of clinical medicine, 1971, Volume: 29, Issue:10

    Topics: Adrenal Cortex Hormones; Anabolic Agents; Cholestasis; Endoplasmic Reticulum; Enzyme Induction; Glucuronates; Humans; Hyperbilirubinemia; Liver; Liver Diseases; Pharmaceutical Preparations; Phenobarbital; Tolbutamide

1971
The expanding role of microsomal enzyme induction, and its implications for clinical chemistry.
    Clinical chemistry, 1980, Volume: 26, Issue:6

    Topics: Acetaminophen; Alcoholism; Animals; Antipyrine; Aryl Hydrocarbon Hydroxylases; Electron Transport; Energy Intake; Enzyme Induction; Epilepsy; Female; Humans; Male; Microsomes, Liver; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Smoking; Tolbutamide; Warfarin

1980
IMPLICATIONS ON ENZYME INDUCTION FOR DRUG THERAPY.
    The American journal of medicine, 1964, Volume: 37

    Topics: Animals; Benzopyrenes; Cyclizine; Dicumarol; Diphenhydramine; Dogs; Drug Therapy; Enzyme Induction; Enzymes; Glutethimide; Hexobarbital; Liver; Meprobamate; Metabolism; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Probenecid; Rats; Research; Tolbutamide; Toxicology; Zoxazolamine

1964

Other Studies

50 other study(ies) available for phenobarbital and tolbutamide

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
    Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4

    Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water

2007
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Drug concentration in saliva.
    Clinical pharmacology and therapeutics, 1978, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Aged; Antipyrine; Chlorpropamide; Humans; Hydrogen-Ion Concentration; Male; Meperidine; Middle Aged; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Propranolol; Protein Binding; Saliva; Tolbutamide

1978
[Effects of combination of anti-epileptic drugs].
    Bibliotheca psychiatrica, 1975, Issue:151

    Topics: Adrenergic beta-Antagonists; Anticonvulsants; Benzodiazepines; Carbamazepine; Digitoxin; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Lithium; Phenobarbital; Phenytoin; Primidone; Thiazines; Tolbutamide; Tranquilizing Agents

1975
Genetic control of tolbutamide metabolism in humans.
    Advances in experimental medicine and biology, 1979, Volume: 119

    Topics: Adolescent; Adult; Aged; Carrier Proteins; Cytochrome P-450 Enzyme System; Diabetes Mellitus; Ethanol; Female; Half-Life; Humans; Kinetics; Male; Microsomes, Liver; Middle Aged; Phenobarbital; Sex Factors; Tolbutamide

1979
The comparative effects of barbituric acid phenobarbital on blood glucose and insulin secretion in mice.
    Diabetologia, 1976, Volume: 12, Issue:3

    Topics: Animals; Barbiturates; Binding, Competitive; Blood Glucose; Glucose Tolerance Test; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Phenobarbital; Tolbutamide

1976
Competition between diftalone and other drugs for the binding site(s) on human serum albumin.
    Medical biology, 1976, Volume: 54, Issue:3

    Topics: Acetaminophen; Aspirin; Binding Sites; Dexamethasone; Drug Interactions; Humans; Indomethacin; Phenobarbital; Phenylbutazone; Phthalazines; Protein Binding; Pyridazines; Serum Albumin; Temperature; Tolbutamide; Warfarin

1976
Alteration of drug metabolism in Gilbert's syndrome.
    Gut, 1976, Volume: 17, Issue:8

    Topics: Adult; Animals; Cytoplasm; Gilbert Disease; Half-Life; Humans; Hyperbilirubinemia, Hereditary; Liver; Male; Phenobarbital; Protein Binding; Rats; Rats, Inbred Strains; Species Specificity; Tolbutamide

1976
[In-vitro studies on the effect of drugs on albumin-bilirubin binding].
    Kinderarztliche Praxis, 1975, Volume: 43, Issue:2

    Topics: Ampicillin; Bilirubin; Humans; In Vitro Techniques; Orotic Acid; Phenobarbital; Phenylbutazone; Protein Binding; Serum Albumin; Sulfamethoxypyridazine; Sulfathiazoles; Tolbutamide

1975
The characteristics of the microsomal hydroxylation of tolbutamide.
    Canadian journal of physiology and pharmacology, 1991, Volume: 69, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Cricetinae; Cytochrome P-450 Enzyme System; Enzyme Induction; Guinea Pigs; Hemeproteins; Hydroxylation; In Vitro Techniques; Isoenzymes; Kinetics; Mice; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rabbits; Rats; Rats, Inbred Strains; Safrole; Species Specificity; Tolbutamide

1991
Drug metabolizing capacity in vitro and in vivo--II. Correlations between hepatic microsomal monooxygenase markers in phenobarbital-induced rats.
    Biochemical pharmacology, 1990, Aug-15, Volume: 40, Issue:4

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Antipyrine; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; In Vitro Techniques; Male; Microsomes, Liver; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Theophylline; Tolbutamide

1990
Drug-protein binding: a method for studying the interactions of drugs with bishydroxycoumarin (dicoumarol) in dogs.
    Annals of the New York Academy of Sciences, 1973, Nov-26, Volume: 226

    Topics: Allopurinol; Animals; Antipyrine; Blood Coagulation; Dicumarol; Dogs; Drug Interactions; Drug Synergism; Enzyme Induction; Half-Life; Liver; Methods; Oxidoreductases; Phenobarbital; Phenylbutazone; Protein Binding; Prothrombin Time; Time Factors; Tolbutamide

1973
[Influence of ethanol on the metabolism of drugs].
    Archivos de biologia y medicina experimentales, 1969, Volume: 3, Issue:Suppl 3

    Topics: Aldrin; Animals; Benzopyrenes; Carcinogens; DDT; Drug Interactions; Ethanol; Histamine H1 Antagonists; Insecticides; Methylcholanthrene; Nikethamide; Pharmaceutical Preparations; Phenobarbital; Phenothiazines; Rats; Tolbutamide

1969
[Activation of liver dopa decarboxylase by inducers of microsomal enzymes].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1967, Volume: 257, Issue:1

    Topics: Animals; Dopa Decarboxylase; Enzyme Induction; Hexachlorocyclohexane; Liver; Microsomes; Phenobarbital; Proadifen; Rats; Stimulation, Chemical; Tolbutamide

1967
[On the activation of dopa decarboxylase and other cytoplasmic liver enzymes by inducers of microsomal enzymes].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1967, Volume: 258, Issue:4

    Topics: Animals; Carboxy-Lyases; Dactinomycin; Dopa Decarboxylase; Enzyme Induction; Ethionine; Hexachlorocyclohexane; L-Lactate Dehydrogenase; Liver; Microsomes; Monoamine Oxidase; Phenobarbital; Proadifen; Rats; Stimulation, Chemical; Tolbutamide

1967
[On 2-benzolsulfonylamino-5(beta-methoxy-ethoxy)-pyrimidine (glycodiazine. V. In vitro and in vivo experiments on the action of phenylethylbarbituric acid (Luminal) on the metabolism and blood sugar reducing effect of glycodiazine].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie und experimentelle Pathologie, 1966, Volume: 255, Issue:2

    Topics: Adult; Animals; Blood Glucose; Dogs; Humans; In Vitro Techniques; Liver; Male; Perfusion; Phenobarbital; Pyrimidines; Rats; Reticulum; Tolbutamide; Tritium

1966
Comparative studies on hepatic N- and O-demethylation.
    Japanese journal of pharmacology, 1972, Volume: 22, Issue:4

    Topics: Aniline Compounds; Animals; Anisoles; Antipyrine; Benzene; Biotransformation; Depression, Chemical; Ethylamines; Female; Hydroxylation; Kinetics; Liver; Methylcholanthrene; Metyrapone; Microsomes, Liver; Phenobarbital; Proadifen; Pyridines; Rats; Stimulation, Chemical; Tolbutamide

1972
Hyperosmolar nonketotic diabetic coma: vascular complications.
    Journal of the American Geriatrics Society, 1974, Volume: 22, Issue:10

    Topics: Adult; Aged; Brain Edema; Diabetic Coma; Diabetic Nephropathies; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Hyperglycemia; Infarction; Intracranial Embolism and Thrombosis; Liver Cirrhosis; Male; Mesenteric Vascular Occlusion; Middle Aged; Osmolar Concentration; Phenobarbital; Pulmonary Embolism; Thromboembolism; Thrombosis; Tolbutamide; Vascular Diseases

1974
Inhibition by ethylmorphine and pentobarbitone in vitro of the metabolism of (ureyl- 14 C)tolbutamide by hepatic microsomal preparations from male and female rats treated with phenobarbitone.
    Biochemical pharmacology, 1972, Jun-01, Volume: 21, Issue:11

    Topics: Animals; Carbon Isotopes; Depression, Chemical; Female; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Morphinans; Pentobarbital; Phenobarbital; Rats; Sex Factors; Tolbutamide

1972
Failure of induction of liver microsomal enzymes by tolbutamide in maturity-onset diabetics.
    Diabetes, 1973, Volume: 22, Issue:3

    Topics: Aged; Diabetes Mellitus; Enzyme Induction; Female; Half-Life; Humans; Male; Microsomes, Liver; Middle Aged; Phenobarbital; Tolbutamide

1973
Inhibition by ethylmorphine and pentobarbitone in vitro of the metabolism of (ureyl- 14 C)tolbutamide by hepatic microsomal preparations from sexually-immature male and female rats treated with phenobarbitone.
    Biochemical pharmacology, 1973, Apr-15, Volume: 22, Issue:8

    Topics: Animals; Carbon Isotopes; Female; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Morphinans; Pentobarbital; Phenobarbital; Rats; Sex Factors; Tolbutamide

1973
Abnormal binding of indocyanine green with serum proteins in a patient with dealyed ICG clearance.
    Clinica chimica acta; international journal of clinical chemistry, 1973, Aug-17, Volume: 47, Issue:1

    Topics: Binding Sites; Chromatography, Gel; Half-Life; Humans; Immunoelectrophoresis; Indocyanine Green; Liver; Male; Middle Aged; Phenobarbital; Protein Binding; Salicylates; Serum Albumin; Spectrophotometry; Spectrophotometry, Ultraviolet; Sulfobromophthalein; Time Factors; Tolbutamide

1973
Evaluation of the toxicity and teratogenecity of drugs.
    Polish journal of pharmacology and pharmacy, 1973, Volume: 25, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Barbiturates; Chick Embryo; Gestational Age; Insulin; Methotrexate; Phenobarbital; Tolbutamide; Toxicology

1973
Determination of sulfonylureas and metabolites by pyrolysis gas chromatography.
    Clinical chemistry, 1974, Volume: 20, Issue:2

    Topics: Amobarbital; Chlorobenzenes; Chlorpropamide; Chromatography, Gas; Evaluation Studies as Topic; Humans; Mass Spectrometry; Methods; Pentobarbital; Phenobarbital; Secobarbital; Structure-Activity Relationship; Sulfonamides; Sulfonylurea Compounds; Time Factors; Tolazamide; Tolbutamide

1974
Studies on synthetic sweetening agents. XV. Metabolism of sodium cyclamate. Influences of phenylbutaone, phenobarbital, and tolbutamide on metabolism of sodium cyclamate in rabbits.
    Chemical & pharmaceutical bulletin, 1972, Volume: 20, Issue:1

    Topics: Animals; Cyclamates; Cyclohexanecarboxylic Acids; Cyclohexylamines; In Vitro Techniques; Liver; Male; Phenobarbital; Phenylbutazone; Rabbits; Sodium; Stimulation, Chemical; Tolbutamide

1972
Non-equivalent preparations of the same drug.
    Drug and therapeutics bulletin, 1971, Aug-13, Volume: 9, Issue:17

    Topics: Chloramphenicol; Dosage Forms; Humans; Nitrofurantoin; Oxytetracycline; Pharmaceutical Preparations; Phenindione; Phenobarbital; Phenylbutazone; Phenytoin; Tetracycline; Therapeutic Equivalency; Tolbutamide; Warfarin

1971
Interactions between digitoxin and other drugs in vitro and in vivo.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: Binding Sites; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Clofibrate; Digitoxin; Digoxin; Drug Antagonism; Enzyme Induction; Erythrocytes; Humans; Microsomes, Liver; Phenobarbital; Phenylbutazone; Phenytoin; Protein Binding; Radioisotopes; Rubidium; Serum Albumin; Sulfadimethoxine; Tolbutamide; Tritium; Warfarin

1971
Effects of various drugs on the uterotropic response to mestranol and norethynodrel in the rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 136, Issue:1

    Topics: Aminosalicylic Acids; Animals; Chlorpromazine; Drug Synergism; Female; Imipramine; Mestranol; Norethynodrel; Organ Size; Phenobarbital; Phenylbutazone; Phenytoin; Proadifen; Rats; Scopolamine; Tolbutamide; Uterus

1971
[Congenital non-hemolytic and non-conjugating-type hyperbilirubinemia].
    Naika. Internal medicine, 1971, Volume: 27, Issue:5

    Topics: Adolescent; Bilirubin; Female; Humans; Hyperbilirubinemia, Hereditary; Indocyanine Green; Iodine Isotopes; Liver; Menthol; Microscopy, Electron; Phenobarbital; Radionuclide Imaging; Sulfobromophthalein; Tolbutamide

1971
The effect of drugs on clinical laboratory determinations.
    Clinical chemistry, 1971, Volume: 17, Issue:5

    Topics: 17-Ketosteroids; Chemistry, Clinical; Drug Antagonism; Drug Synergism; Drug Therapy; Hemorrhage; Humans; Nalidixic Acid; Pharmaceutical Preparations; Phenobarbital; Phenylbutazone; Steroids; Tolbutamide; Urine; Warfarin

1971
Properties of 3-(1-phenyl-propyl)-4-oxycoumarin (marcoumar) in the plasma when tested in normal cases and under the influence of drugs.
    Thrombosis et diathesis haemorrhagica, 1968, Jul-31, Volume: 19, Issue:3

    Topics: Blood Proteins; Coumarins; Drug Synergism; Ethyl Biscoumacetate; Fluorometry; Phenobarbital; Phenylbutazone; Protein Binding; Spectrophotometry; Sulfadimethoxine; Sulfinpyrazone; Tolbutamide

1968
[On the resportion profile of drugs. 2. On studies with the resorption model].
    Arzneimittel-Forschung, 1966, Volume: 16, Issue:10

    Topics: Absorption; Antipyrine; Aspirin; Codeine; Hydrogen-Ion Concentration; Models, Biological; Phenacetin; Phenobarbital; Tolbutamide

1966
Variability of uniformity of weight test as an indicator of the amount of active ingredient in tablets.
    Journal of pharmaceutical sciences, 1967, Volume: 56, Issue:2

    Topics: Chemical Phenomena; Chemistry; Isoniazid; Phenobarbital; Phenylbutazone; Promazine; Tablets; Tolbutamide

1967
Effect of some therapeutic agents on the rabbit fetus.
    Toxicology and applied pharmacology, 1967, Volume: 10, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Aspirin; Dimenhydrinate; Female; Fetus; Glutethimide; Methaqualone; Phenobarbital; Rabbits; Thalidomide; Tolbutamide; Tranquilizing Agents; Uterus

1967
Tolbutamide as a model drug for the study of enzyme induction and enzyme inhibition in the rat.
    British journal of pharmacology, 1984, Volume: 81, Issue:3

    Topics: Animals; Chloroquine; Cimetidine; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Kinetics; Male; Phenobarbital; Primaquine; Rats; Rats, Inbred Strains; Substrate Specificity; Tolbutamide

1984
DRUG-INDUCED CHANGES IN THE LIVER ENDOPLASMIC RETICULUM: ASSOCIATION WITH DRUG-METABOLIZING ENZYMES.
    Science (New York, N.Y.), 1963, Dec-27, Volume: 142, Issue:3600

    Topics: Adenosine Triphosphatases; Animals; Cytochromes; Endoplasmic Reticulum; Liver; Meprobamate; Microscopy, Electron; N-Glycosyl Hydrolases; Nikethamide; Nitrogen; Orphenadrine; Pharmacology; Phenobarbital; Phenylbutazone; Phosphoric Monoester Hydrolases; Phosphorus; Tolbutamide

1963
ENHANCED SULFOBROMOPHTHALEIN DISAPPEARANCE IN MICE PRETREATED WITH VARIOUS DRUGS.
    Biochemical pharmacology, 1965, Volume: 14

    Topics: Countercurrent Distribution; Ethionine; Liver; Metabolism; Mice; Nikethamide; Pharmacology; Phenobarbital; Proadifen; Research; Sulfobromophthalein; Tolbutamide; Urethane

1965
EFFECT OF DRUGS ON THE FORMATION OF SMOOTH ENDOPLASMIC RETICULUM AND DRUG-METABOLIZING ENZYMES.
    Annals of the New York Academy of Sciences, 1965, Mar-12, Volume: 123

    Topics: Animals; Electrons; Endoplasmic Reticulum; Endoplasmic Reticulum, Smooth; Esterases; Hexobarbital; Histocytochemistry; Liver; Microscopy; Microscopy, Electron; Oxidoreductases; Pathology; Pharmacology; Phenobarbital; Rats; Research; Spectrophotometry; Tolbutamide; Toxicology

1965
Rabbit dehydrogenase/reductase SDR family member 11 (DHRS11): Its identity with acetohexamide reductase with broad substrate specificity and inhibitor sensitivity, different from human DHRS11.
    Chemico-biological interactions, 2019, May-25, Volume: 305

    Topics: 17-Hydroxysteroid Dehydrogenases; Acetohexamide; Alcohol Oxidoreductases; Amino Acid Sequence; Animals; Catalytic Domain; Diclofenac; Humans; Kinetics; Male; Mutagenesis; Myocardium; Phenobarbital; Rabbits; Recombinant Proteins; Sequence Alignment; Substrate Specificity; Tolbutamide

2019