phenobarbital has been researched along with thyroxine in 113 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 77 (68.14) | 18.7374 |
| 1990's | 15 (13.27) | 18.2507 |
| 2000's | 15 (13.27) | 29.6817 |
| 2010's | 6 (5.31) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strassburg, CP; Tukey, RH | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Selye, H; Taché, J; Taché, Y | 1 |
| Ganes, T; Johannessen, SI; Rootwelt, K | 1 |
| Pansegrouw, D | 1 |
| Accatino, L; Simon, FR; Sutherland, E | 1 |
| Adelman, RC | 1 |
| Alexander, WD; Evered, DC; Lees, JF; Lewis, M | 1 |
| Fichsel, H; Knöpfle, G | 1 |
| Bouhnik, J; Michel, R; Naltchayan, S; Négrié, C | 1 |
| Sies, H; Stokstad, EL; Waydhas, C | 1 |
| Bates, D; Evered, DC; Heath, A; Howe, JG; Ratcliffe, WA; Schardt, CW; Yeo, PP | 1 |
| Paumgartner, G | 1 |
| Conney, AH; Jacobson, MM; Levin, W | 1 |
| Dutton, GJ; Leakey, JE | 1 |
| Hüfner, M; Knöpfle, M | 1 |
| Hales, BF; Neims, AH | 1 |
| Morrissey, KP | 1 |
| Catinot, R; Cordier, A; de Sandro, V; Kriszt, W; Richert, L | 1 |
| Deluca, JG; Germershausen, JI; Gerson, RJ; Gordon, LR; Grossman, SJ; MacDonald, JS; Majka, JA; Smith, PF; Wang, RW | 1 |
| Boddaert, A; Chevrier, M; Cordier, A; De Sandro, V; Melcion, C; Richert, L | 1 |
| Nugon-Baudon, L; Rabot, S; Raibaud, P; Szylit, O | 1 |
| Fandrey, J; Jelkmann, W; Seydel, FP; Siegers, CP | 1 |
| Zbinden, G | 1 |
| Catto, L; Jones, RB; Leonard, T; Poole, A; Pritchard, D | 1 |
| Downing, JC; Levin, AA; McClain, RM; Posch, R | 1 |
| Levy, G; Walker, JS | 1 |
| Kanto, WP; Karp, WB; Robertson, AF | 1 |
| Hashimoto, H; Hiasa, Y; Katoh, Y; Kitahori, Y; Konishi, N; Minami, S; Murata, Y; Ohshima, M; Sakaguchi, Y; Shimoyama, T | 1 |
| Kodama, S; Komatsu, M; Konishi, H; Matsuo, T; Momota, K; Tanaka, K; Yokoyama, S | 1 |
| Weissel, M | 1 |
| Feely, M; Griffiths, AP; Peaker, S; Penn, ND; Tindall, H | 1 |
| Kaciński, M; Stopyrowa, J; Szafran, Z; Sztefko, K | 1 |
| Boccuzzi, G; Guglielmone, R; Ugazio, G | 1 |
| Armstrong, JM; Bosakowski, T; McClain, RM; Posch, RC | 1 |
| Gupta, MP; Khanduja, KL; Koul, A; Koul, IB; Pathak, CM; Sharma, RR; Vaidyanathan, S | 1 |
| Mannering, GJ | 1 |
| Horiguchi, T | 1 |
| Lüders, D | 2 |
| Withers, BT | 1 |
| Mécs, I; Selye, H; Szabo, S | 2 |
| Kourounakis, P; Selye, H; Szabo, S | 3 |
| Gerdes, H; Joseph, K; Littmann, KP; Mahlstedt, J | 1 |
| Oppenheimer, JH | 1 |
| Irvine, CH | 1 |
| Kozyreff, V; Oppenheimer, JH; Surks, MI | 1 |
| Myant, NB | 1 |
| Selye, H | 3 |
| Reynolds, JW | 1 |
| Becker, CE; Cavlieri, RR; Sung, LC | 1 |
| Phillips, WA; Schultz, JR; Stafford, WW | 1 |
| Lipsett, MB | 1 |
| Artz, SA; Bernstein, G; Hasen, J; Oppenheimer, JH | 1 |
| Oppenheimer, JH; Schwartz, HL; Surks, MI | 2 |
| Selye, H; Szabo, S | 1 |
| Kramer, RL; Richens, A | 1 |
| Kato, R; Takahashi, A | 1 |
| Kato, R; Oshima, T; Takayanagi, M | 1 |
| Hirata, K; Nakao, K; Sakamoto, Y; Wada, F | 1 |
| Fernandez, EP; Hsia, SL; Voigt, W | 1 |
| Bernstein, G; Oppenheimer, JH; Schwartz, HL; Shapiro, HC; Surks, MI | 1 |
| Oppenheimer, JH; Schwartz, HL; Shapiro, HC; Surks, MI | 1 |
| Klaassen, CD | 1 |
| Bernstein, G; Oppenheimer, JH; Surks, MI | 1 |
| Goldstein, JA; Taurog, A | 1 |
| Bernstein, G; Oppenheimer, JH; Schwartz, HL | 1 |
| Ogunlana, EO; Ramstad, E; Tyler, VE | 1 |
| Kozyreff, V; Oppenheimer, JH; Schwartz, HL; Surks, MI | 1 |
| de-Andrade-Silva, E; de-Araujo, PS; Raw, I | 1 |
| Carin, I; Glass, L; Parekh, A; Solomon, N; Steigman, J; Wong, S | 1 |
| Bollati, A; Caminiti, A; Focarile, F; Grasso, E; Rondanini, GF; Zanini, R | 1 |
| Börner, W; Hoffmann, R; Moll, E; Reiners, C | 1 |
| Burger, A; Bürgi, H; Ohnhaus, EE; Studer, H | 1 |
| Matsubara, T; Ogawa, A; Touchi, A | 1 |
| Brewer, ED; Conley, SB; Richards, GE; Saldana, LR | 1 |
| Axelrod, J; Hoffman, AR; Paul, SM | 1 |
| Danilova, NP | 1 |
| Johnson, S; McKillop, D; Miller, J; Smith, IK | 1 |
| Grüters, A; Hüfner, M; Lakomek, M; Roth, C; Siggelkow, H | 1 |
| Daminet, S; Paradis, M; Price, C; Refsal, KR | 1 |
| Kantrowitz, LB; Melián, C; Nichols, R; Peterson, ME; Trepanier, LA | 1 |
| Hirsch-Ernst, KI; Jungermann, K; Kahl, GF; Kietzmann, T | 1 |
| Brimacombe, MB; Burton, SA; Cribb, AE; Gaskill, CL; Gelens, HC; Ihle, SL; Miller, JB; Shaw, DH | 2 |
| Hack, JB; Hoffman, RS; Leviss, JA; Nelson, LS | 1 |
| Hashmi, R; Hood, A; Klaassen, CD | 1 |
| Castro-Gago, M; Del Río-Garma, M; Del Río-Garma, MC; Eirís-Puñal, J; Lojo-Rocamonde, S; Novo-Rodríguez, I | 1 |
| Hood, A; Klaassen, CD | 1 |
| Kajimura, T; Nomura, M; Ohno, H; Satoh, H; Sugawara, T; Tsuchiya, Y | 1 |
| Inoue, Y; Kurata, Y; Makinodan, F; Tanaka, K; Wako, Y | 1 |
| Carney, EW; Crissman, JW; Marty, MS | 1 |
| Hirose, M; Ikeda, T; Imazawa, T; Kimura, S; Miyauchi, M; Nakamura, H; Nishikawa, A; Son, HY | 1 |
| TERVOOREN, U; VOGEL, G | 1 |
| Kawamura, S; Kunimatsu, T; Mikami, N; Miyata, K; Okuno, Y; Seki, T; Sukata, T; Yabushita, S; Yamada, T | 1 |
| Moore, DD; Qatanani, M; Zhang, J | 1 |
| Degawa, M; Ikushiro, S; Kato, Y; Suzuki, H; Yamada, S | 1 |
| Baginskaia, NV; Il'nitskaia, SI; Kaledin, VI; Kholodar', AV; Obut, TA | 1 |
| Coelho-Palermo Cunha, G; van Ravenzwaay, B | 1 |
| Bergman, A; Brouwer, A; Hamers, T; Kamstra, JH; Murk, AJ; Sonneveld, E; Van Velzen, MJ; Visser, TJ | 1 |
| Andres, J; Bode, LM; Carnevali, LC; Hirsch-Ernst, KI; Kuna, M; Neuschäfer-Rube, F; Püschel, GP; Wieneke, N | 1 |
| Degawa, M; Haraguchi, K; Ikushiro, S; Ito, Y; Kato, Y; Suzuki, H; Uchida, S; Yamada, S | 1 |
| de Rijke, YB; van Toor, H; Visser, TJ; Visser, WE | 1 |
| Ishiguro, T; Kawakami, Y; Kumazawa, T; Li, Y; Matsumoto, Y; Nishitani, H; Tagawa, Y | 1 |
13 review(s) available for phenobarbital and thyroxine
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Disruptions in enzyme regulation during aging.
Topics: Aging; Animals; Corticosterone; Cytochrome Reductases; Enzyme Induction; Enzymes; Female; Genes; Glucagon; Glucokinase; Hydrocortisone; Insulin; Liver; Male; Microsomes, Liver; Phenobarbital; Rats; Thyroxine; Tyrosine Transaminase | 1975 |
[What is reliable in the internal therapy of the gallstone trouble?].
Topics: Bile; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Clofibrate; Diet; Dose-Response Relationship, Drug; Estrogens; Humans; Lipid Metabolism; Liver; Phenobarbital; Thyroxine | 1975 |
Effects of drugs on the metabolism of bilirubin and other normal body constituents.
Topics: Animals; Bilirubin; DDT; Estrogens; Female; Glucuronates; Humans; Hydroxylation; Infant; Infant, Newborn; Jaundice, Neonatal; Liver; Male; Microsomes, Liver; Pharmacology; Phenobarbital; Pregnancy; Steroids; Testosterone; Thyroxine; Transferases | 1976 |
Current concepts of gallstone formation.
Topics: Animals; Bile; Bile Acids and Salts; Cholecystectomy; Cholelithiasis; Cholesterol; Cholestyramine Resin; Clofibrate; Diet; Gallbladder; Hormones; Humans; Metabolic Diseases; Nicotinic Acids; Phenobarbital; Phosphatidylcholines; Phospholipids; Thyroxine | 1975 |
[Modification of peripheral thyroid hormone metabolism by drugs].
Topics: Amiodarone; Antipyrine; Dexamethasone; Heparin; Humans; Phenobarbital; Phenytoin; Propranolol; Protein Binding; Rifampin; Thiouracil; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine | 1988 |
Interaction of drugs with thyroid hormone binding sites.
Topics: Binding Sites; Blood Proteins; Cell Nucleus; Drug Interactions; Endoplasmic Reticulum; Graves Disease; Humans; Kinetics; Liver; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin; Thyroid Hormones; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine | 1973 |
[The pros and cons of luminal teatment of hyperbilirubinemia].
Topics: Adrenocorticotropic Hormone; Animals; Bilirubin; Central Nervous System; Cholesterol; Drug Eruptions; Enzyme Induction; Humans; Hyperbilirubinemia, Hereditary; Infant, Newborn; Jaundice, Neonatal; Liver; Mice; Phenobarbital; Rats; Serum Albumin; Steroids; Thyroxine | 1970 |
Effects of drugs on the metabolism of bile acids.
Topics: Animals; Bile Acids and Salts; Biological Transport; Biological Transport, Active; Carbon Radioisotopes; Chenodeoxycholic Acid; Cholesterol; Cholestyramine Resin; Cholic Acids; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Humans; Hydroxycholesterols; Ileum; Intestinal Mucosa; Liver; Liver Circulation; Mixed Function Oxygenases; Phenobarbital; Propylthiouracil; Rats; Sulfathiazoles; Taurine; Thyroid Gland; Thyroxine; Triiodothyronine; Vitamins | 1972 |
Protection by catatoxic steroids against cyclophosphamide-induced organ lesions.
Topics: Adrenal Glands; Animals; Body Weight; Bone Marrow; Cyclophosphamide; Desoxycorticosterone; Enzyme Induction; Estradiol; Ethylestrenol; Female; Ketones; Microsomes, Liver; Mortality; Oxandrolone; Phenobarbital; Prednisolone; Pregnancy; Pregnanediones; Pregnanes; Pregnenolone; Progesterone; Rats; Spironolactone; Thyroxine; Triamcinolone | 1970 |
The use of drugs in influencing human fetal metabolism.
Topics: Adrenocortical Hyperfunction; Animals; Blood Transfusion, Intrauterine; Congenital Hypothyroidism; Erythroblastosis, Fetal; Estrogens; Ethanol; Extraembryonic Membranes; Female; Fetal Diseases; Fetus; Glucocorticoids; Heroin; Humans; Hyaline Membrane Disease; Hydrocortisone; Hypoprothrombinemias; Infant, Newborn; Infant, Newborn, Diseases; Isoxsuprine; Jaundice, Neonatal; Lung; Maternal-Fetal Exchange; Phenobarbital; Pregnancy; Pulmonary Surfactants; Rabbits; Rats; Thyroxine; Vitamin D | 1974 |
Factors influencng the rate of metabolism of steroid hormones in man.
Topics: Aldosterone; Androgens; Barbiturates; DDT; Dichlorodiphenyldichloroethane; Estradiol; Estrogens; Hormones; Humans; Hydrocortisone; Metabolism; Microsomes, Liver; Phenobarbital; Phenytoin; Progesterone; Protein Binding; Steroids; Testosterone; Thyroxine | 1971 |
2 trial(s) available for phenobarbital and thyroxine
| Article | Year |
|---|---|
Neonatal methadone withdrawal. Effect of two treatment regimens.
Topics: Blood Pressure; Carbon Dioxide; Drug Administration Schedule; Female; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Methadone; Opium; Phenobarbital; Pregnancy; Random Allocation; Respiration; Substance Withdrawal Syndrome; Thyroxine; Time Factors | 1983 |
The effect of antipyrine, phenobarbitol and rifampicin on thyroid hormone metabolism in man.
Topics: Adult; Antipyrine; Enzyme Induction; Female; Humans; Male; Microsomes, Liver; Phenobarbital; Rifampin; Thyroid Hormones; Thyrotropin; Thyroxine | 1981 |
98 other study(ies) available for phenobarbital and thyroxine
| Article | Year |
|---|---|
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Inhibition of the effects of alfathesin and other steroid anesthetics by catatoxic steroids in rats.
Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Female; Ketosteroids; Phenobarbital; Phenytoin; Prednisolone; Pregnanediones; Pregnanes; Pregnenes; Pregnenolone Carbonitrile; Rats; Spironolactone; Steroids; Thyroxine; Time Factors | 1975 |
Effect of carbamazepine, phenytoin and phenobarbitone on serum levels of thyroid hormones and thyrotropin in humans.
Topics: Adult; Carbamazepine; Epilepsy; Humans; Phenobarbital; Phenytoin; Radioimmunoassay; Thyroid Hormones; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Time Factors; Triiodothyronine; Triiodothyronine, Reverse | 1978 |
The inhibition of c-AMP-phosphodiesterase by phenobarbitone.
Topics: Aniline Compounds; Animals; Cattle; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Myocardium; Phenobarbital; Phosphodiesterase Inhibitors; Rats; Stimulation, Chemical; Theophylline; Thyroxine; Tritium | 1975 |
Stimulation of hepatic sodium and potassium-activated adenosine triphosphatase activity by phenobarbital. Its possible role in regulation of bile flow.
Topics: Adenosine Triphosphatases; Animals; Bile; Bile Acids and Salts; Cycloheximide; Glucose-6-Phosphatase; Kinetics; Liver; Male; Nucleotidases; Organ Specificity; Phenobarbital; Potassium; Rats; Sodium; Subcellular Fractions; Thyroid Gland; Thyroxine | 1977 |
Role of TSH in the changes in thyroidal metabolism of [35S]methimazole in phenobarbital and thyroxine-treated rats.
Topics: Animals; Methimazole; Phenobarbital; Rats; Rats, Inbred Strains; Thyroid Gland; Thyrotropin; Thyroxine | 1977 |
[The effect of primidone treatment of thyroid hormones in epileptic children and adolescents (author's transl)].
Topics: Adolescent; Child; Enzyme Induction; Epilepsy; Female; Humans; Iodine; Liver; Male; Phenobarbital; Primidone; Thyroid Gland; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Time Factors | 1977 |
Comparative effects of dexamethasone and phenobarbital on adrenal cortex, liver cytochrome P450 contents and serum thyroid hormones.
Topics: Adrenal Cortex; Animals; Cytochrome P-450 Enzyme System; Dexamethasone; Male; Microsomes; Microsomes, Liver; Mitochondria; Molecular Weight; Phenobarbital; Proteins; Rats; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1979 |
Methionine and thyroid hormone effects on 14CO2 exhalation from [dimethylamino-14C]aminopyrine in intact phenobarbital-pretreated rats.
Topics: Aminopyrine; Animals; Carbon Dioxide; Carbon Radioisotopes; Male; Methionine; Phenobarbital; Rats; Respiration; Thyroidectomy; Thyroxine | 1979 |
Anticonvulsants and thyroid function.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine | 1978 |
Precocious development of uridine diphosphate glucuronyltransferase activity in chick-embryo liver after administration of 11beta-hydroxy steroids with and without thyroxine.
Topics: Animals; Chick Embryo; Enzyme Activation; Enzyme Induction; Glucuronosyltransferase; Hydroxysteroids; Liver; Phenobarbital; Thyroxine | 1976 |
Pharmacological influences on T4 to T3 conversion in rat liver.
Topics: Animals; Dexamethasone; Kinetics; Liver; Phenobarbital; Phenytoin; Rats; Thyroxine; Triiodothyronine | 1976 |
Developmental aspects of glutathione S-transferase B (ligandin) in rat liver.
Topics: Animals; Animals, Newborn; Dinitrobenzenes; Dinitrochlorobenzene; Enzyme Induction; Glutathione Transferase; Hydrocortisone; Liver; Male; Phenobarbital; Rats; Thyroxine | 1976 |
Male rat hepatic UDP-glucuronosyltransferase activity toward thyroxine. Activation and induction properties--relation with thyroxine plasma disappearance rate.
Topics: Animals; Detergents; Enzyme Activation; Enzyme Induction; Glucuronosyltransferase; Liver; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Thyrotropin; Thyroxine; Triiodothyronine | 1992 |
Studies on the mechanism of simvastatin-induced thyroid hypertrophy and follicular cell adenoma in the rat.
Topics: Adenoma; Animals; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy; Liver; Lovastatin; Microsomes, Liver; Organ Size; Phenobarbital; Rats; Rats, Inbred Strains; Simvastatin; Thyroid Gland; Thyroid Hormones; Thyroid Neoplasms; Thyroxine; Time Factors | 1991 |
Comparison of the effects of propylthiouracil, amiodarone, diphenylhydantoin, phenobarbital, and 3-methylcholanthrene on hepatic and renal T4 metabolism and thyroid gland function in rats.
Topics: Amiodarone; Animals; Body Weight; Cytochrome P-450 Enzyme System; Cytochromes b5; Glucuronosyltransferase; Kidney; Liver; Male; Methylcholanthrene; Microsomes, Liver; Organ Size; Oxygenases; Phenobarbital; Phenytoin; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 1991 |
Glucosinolates toxicity in growing rats: interactions with the hepatic detoxification system.
Topics: Animals; Brassica; Cytochrome P-450 Enzyme System; Diet; Eating; Glucosinolates; Glucuronosyltransferase; Glutathione Transferase; Glycine max; Inactivation, Metabolic; Male; Microsomes, Liver; Organ Size; Phenobarbital; Rats; Thioglycosides; Thyroxine; Triiodothyronine; Weight Gain | 1990 |
Role of cytochrome P450 in the control of the production of erythropoietin.
Topics: Carcinoma, Hepatocellular; Cobalt; Cysteamine; Cytochrome P-450 Enzyme System; Ditiocarb; Erythropoietin; Humans; Liver Neoplasms; Methylcholanthrene; Metyrapone; Microsomes; Oxygen; Phenobarbital; Thyroxine; Triiodothyronine; Tumor Cells, Cultured | 1990 |
Evaluation of thyroid gland activity by hormone assays and flow cytometry in rats.
Topics: Animals; Antithyroid Agents; Cell Cycle; Flow Cytometry; Male; Methimazole; Phenobarbital; Phenylenediamines; Rats; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 1988 |
In vitro accumulation of thyroid hormones by cultured rat hepatocytes and the biliary excretion of iodothyronines in rats treated with a novel histamine H2-receptor antagonist.
Topics: Animals; Bile; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Histamine H2 Antagonists; Liver; Male; Phenobarbital; Pyrimidinones; Rats; Rats, Inbred Strains; Temperature; Thyroid Hormones; Thyroxine; Triazoles; Triiodothyronine | 1989 |
The effect of phenobarbital on the metabolism and excretion of thyroxine in rats.
Topics: Animals; Bile; Drug Interactions; Female; Iodine Radioisotopes; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Thyroid Gland; Thyroidectomy; Thyroxine | 1989 |
Kinetics of drug action in disease states. XXXIV. Effect of experimental thyroid disorders on the pharmacodynamics of phenobarbital, ethanol and pentylenetetrazol.
Topics: Animals; Dose-Response Relationship, Drug; Ethanol; Female; Pentylenetetrazole; Phenobarbital; Rats; Rats, Inbred Lew; Thyroid Diseases; Thyroxine | 1989 |
The effect of hydrocortisone, thyroxine, and phenobarbital on diamine oxidase activity in newborn rat intestine.
Topics: Amine Oxidase (Copper-Containing); Animals; Animals, Newborn; beta-Fructofuranosidase; Glycoside Hydrolases; Hydrocortisone; Intestines; Phenobarbital; Rats; Rats, Inbred Strains; Thyroxine | 1987 |
Effects of castration before and after treatment with N-bis (2-hydroxypropyl)-nitrosamine (DHPN) on the development of thyroid tumors in rats treated with DHPN followed by phenobarbital.
Topics: Animals; Body Weight; Gonadal Steroid Hormones; Hyperplasia; Male; Nitrosamines; Orchiectomy; Organ Size; Phenobarbital; Rats; Thyroid Gland; Thyroid Neoplasms; Thyrotropin; Thyroxine | 1987 |
Thyroid function in children with long-term anticonvulsant treatment.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Female; Humans; Infant; Male; Osmolar Concentration; Phenobarbital; Resins, Plant; Thyroid Gland; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Time Factors; Triiodothyronine; Valproic Acid | 1987 |
Use of a pharmacological indicator to monitor compliance with thyroxine.
Topics: Adult; Aged; Humans; Hypothyroidism; Middle Aged; Patient Compliance; Phenobarbital; Thyrotropin; Thyroxine; Time Factors | 1988 |
[Serum levels of triiodothyronine, thyroxine and thyrotropin in children with epilepsy treated with amizepine, luminal and mizodine in a monotherapy system. Preliminary report].
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Male; Phenobarbital; Primidone; Thyrotropin; Thyroxine; Triiodothyronine | 1988 |
Failure of phenobarbitone to potentiate the adverse effects of two ethylene-bis-dithiocarbamate (EBDC) fungicides.
Topics: Animals; Body Weight; Drug Synergism; Female; Liver; Male; Maneb; Phenobarbital; Rats; Rats, Inbred Strains; Sex Factors; Thiocarbamates; Thyroid Gland; Thyroxine; Triglycerides; Triiodothyronine; Zineb | 1988 |
Studies on the mode of action for thyroid gland tumor promotion in rats by phenobarbital.
Topics: Animals; Body Weight; Cell Transformation, Neoplastic; Eating; Female; Male; Nitrosamines; Organ Size; Phenobarbital; Rats; Thyroid Neoplasms; Thyrotropin; Thyroxine | 1988 |
Effect of phenobarbital & 3-methylcholanthrene treatment on thyroid hormones in rat.
Topics: Animals; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains; Thyroid Hormones; Thyroxine; Triiodothyronine | 1987 |
Properties of cytochrome P-450 as affected by environmental factors: qualitative changes due to administration of polycyclic hydrocarbons.
Topics: Animals; Binding Sites; Chemical Phenomena; Chemistry; Cyanides; Cytochromes; Electron Transport; Environment; Hydrocarbons; Hydrogen-Ion Concentration; Methylcholanthrene; Microsomes, Liver; Morpholines; Phenobarbital; Polycyclic Compounds; Spectrum Analysis; Thyroxine | 1971 |
[Clinical study on determination of blood thyroid hormone levels using the protein binding test--free thyroxine index in young children].
Topics: Age Factors; Androgens; Antithyroid Agents; Child; Child, Preschool; Down Syndrome; Dwarfism, Pituitary; Estrogens; Female; Goiter; Humans; Hyperthyroidism; Hypothyroidism; Infant; Iodine; Male; Nephrotic Syndrome; Obesity; Penicillins; Phenobarbital; Phenytoin; Thyroid Function Tests; Thyroiditis; Thyroxine; Umbilical Arteries | 1971 |
[Influence of phenobarbital treatment on thyroid function in Wistar and Gunn rats. Experiments with 125 I-thyroxine].
Topics: Animals; Bile; Feces; Female; Iodine Radioisotopes; Kidney; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Thyroid Function Tests; Thyroid Gland; Thyroxine | 1972 |
Hypometabolism in allergy: a review for otolaryngologists.
Topics: Adult; Animals; Basal Metabolism; Cattle; Desensitization, Immunologic; Energy Transfer; Female; Humans; Hypersensitivity; Male; Middle Aged; Phenobarbital; Protein Biosynthesis; Thyroid Function Tests; Thyroid Hormones; Thyroxine; Triiodothyronine | 1974 |
Protection by catatoxic steroids against the paralysis caused by combined treatment with thyroxine and methylphenidate.
Topics: Androstenols; Animals; Drug Synergism; Estradiol; Ethylestrenol; Female; Humans; Hydroxysteroids; Hyperkinesis; Ketosteroids; Methylphenidate; Norpregnanes; Paralysis; Phenobarbital; Phenytoin; Prednisolone; Pregnenolone Carbonitrile; Progesterone; Propionates; Rats; Rats, Inbred Strains; Spironolactone; Steroids; Thyroxine | 1972 |
Effect of pharmacologic conditioning on sulfadiazine toxicity and concentrations in plasma.
Topics: Adrenocorticotropic Hormone; Androstenols; Animals; Depression, Chemical; Desoxycorticosterone; Estradiol; Female; Ketosteroids; Kidney; Organ Size; Phenobarbital; Prednisolone; Pregnanediones; Pregnenolone Carbonitrile; Propionates; Rats; Spironolactone; Stimulation, Chemical; Sulfadiazine; Thyroxine; Triamcinolone | 1974 |
[Lithium therapy of thyrotoxicosis. Clinical experiences and results with a new therapeutic principle].
Topics: Adult; Aged; Female; Follow-Up Studies; Humans; Hyperthyroidism; Iodine Radioisotopes; Lithium; Long-Term Care; Male; Middle Aged; Phenobarbital; Prednisone; Technetium; Thyroid Crisis; Thyroxine; Triiodothyronine | 1973 |
The effect of an ethanol-extractable thyroxine binding substance in plasma on the measurement of thyroxine by competitive binding.
Topics: Adult; Binding, Competitive; Buffers; Ethanol; Humans; Hydrogen-Ion Concentration; Iodine Radioisotopes; Middle Aged; Phenobarbital; Polysaccharides; Resins, Plant; Thyroxine; Thyroxine-Binding Proteins; Tromethamine | 1974 |
Demonstration of membrane-linked iodoprotein in hepatic microsomes following metabolism of the thyroid hormones.
Topics: Animals; Centrifugation, Density Gradient; Glucose-6-Phosphatase; Iodine; Iodine Isotopes; Iodoproteins; Liver; Membranes; Microsomes, Liver; Phenobarbital; Proteins; Rats; Ribosomes; RNA; Serum Albumin, Radio-Iodinated; Spectrophotometry; Thyroxine; Triiodothyronine | 1970 |
Protection against the neurolathyrism produced by arsanilic acid in the rat.
Topics: 5-Hydroxytryptophan; Animals; Arsenic Poisoning; Biotransformation; Desoxycorticosterone; Female; Hormones; Movement Disorders; Phenobarbital; Phenytoin; Pregnenolone; Rats; Serotonin; Steroids; Thyroxine; Triamcinolone | 1972 |
Prevention by catatoxic steroids of lithocholic acid-induced biliary concrements in the rat.
Topics: Animals; Bile Acids and Salts; Body Weight; Common Bile Duct; Female; Gallstones; Jaundice; Lithocholic Acid; Liver; Nitriles; Phenobarbital; Phenytoin; Prednisolone; Propionates; Rats; Steroids; Thyroxine; Triamcinolone; Triiodothyronine | 1972 |
Effects of phenobarbital on thyroxine and triiodothyronine kinetics in Graves' disease.
Topics: Feces; Female; Graves Disease; Humans; Iodine Isotopes; Kinetics; Liver; Male; Phenobarbital; Radioimmunoassay; Thyroxine; Triiodothyronine | 1973 |
Effects of colestipol hydrochloride on drug absorption in the rat. I. Aspirin, L-thyroxine, phenobarbital, cortisone, and sulfadiazine.
Topics: Analysis of Variance; Animals; Anticholesteremic Agents; Aspirin; Carbon Radioisotopes; Cholestyramine Resin; Cortisone; Ethers, Cyclic; Intestinal Absorption; Kinetics; Male; Phenobarbital; Polyamines; Polymers; Rats; Statistics as Topic; Sulfadiazine; Sulfur Radioisotopes; Thyroxine | 1974 |
Hepatic accumulation of 125I-thyroxine in the rat: augmentation by phenobarbital and chlordane.
Topics: Animals; Benzopyrenes; Chlordan; Iodine Radioisotopes; Liver; Male; Phenobarbital; Radioisotope Dilution Technique; Rats; Thyroxine | 1968 |
The metabolic significance of exchangeable cellular thyroxine.
Topics: Animals; Biological Transport; Humans; Iodine; Iodine Isotopes; Kidney; Kinetics; Liver; Phenobarbital; Rats; Serum Albumin, Radio-Iodinated; Stimulation, Chemical; Thyroid Gland; Thyroidectomy; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine | 1969 |
Effect of various steroids and nonsteroidal microsomal enzyme inducers upon propoxyphene intoxication.
Topics: Animals; Dextropropoxyphene; Enzyme Induction; Estradiol; Female; Phenobarbital; Phenytoin; Poisoning; Prednisolone; Rats; Thyroxine; Triamcinolone | 1972 |
Protection against haloperidol by catatoxic steroids.
Topics: Animals; Central Nervous System; Drug Antagonism; Drug Synergism; Ethylestrenol; Female; Haloperidol; Ketones; Nitriles; Oxandrolone; Phenobarbital; Prednisolone; Pregnanes; Pregnenolone; Progesterone; Rats; Spironolactone; Thyroxine; Triamcinolone | 1972 |
Two dimensional immunoelectrophoresis of human serum proteins for the investigation of protein drugs.
Topics: Aspirin; Blood Proteins; Carbon Isotopes; Humans; Immunoelectrophoresis; Iodine Isotopes; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin; Thyroxine | 1972 |
Protection by catatoxic steroids and related compounds against proscillaridin intoxication.
Topics: Anabolic Agents; Androstanes; Animals; Bufanolides; Digitoxin; Ethylestrenol; Female; Glucocorticoids; Hydroxysteroids; Ketosteroids; Phenobarbital; Pregnanes; Pregnenolone; Propionates; Rats; Rats, Inbred Strains; Seizures; Spironolactone; Thyroxine | 1972 |
Protection against LSD by various steroids.
Topics: Anabolic Agents; Animals; Estradiol; Ethylestrenol; Female; Lysergic Acid Diethylamide; Movement Disorders; Phenobarbital; Prednisolone; Pregnenolone; Progesterone; Rats; Steroids; Thyroxine; Triamcinolone | 1971 |
Effect of phenobarbital on the activities of drug-metabolizing enzymes and electron transport system of liver microsomes in alloxan diabetes and thyroxine treated rats.
Topics: Animals; Diabetes Mellitus, Experimental; Electron Transport; Female; Liver; Microsomes; Organ Size; Phenobarbital; Proteins; Rats; Stimulation, Chemical; Thyroxine | 1969 |
Differences in the oxidative metabolism of drugs by liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Female; Hexobarbital; Liver; Male; Methylcholanthrene; Microsomes; Oxidation-Reduction; Oxidoreductases; Pentobarbital; Phenobarbital; Proadifen; Rats; Sex Factors; Starvation; Thyroxine; Zoxazolamine | 1969 |
Participation of the microsomal electron transport system involving cytochrome P-450 in 7alpha-hydroxylation of cholesterol.
Topics: Animals; Antibodies; Biliary Fistula; Carbon Isotopes; Carbon Monoxide; Cholesterol; Cytochromes; Electron Transport; Fasting; Hydrocortisone; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Proteins; Rabbits; Rats; Thyroxine | 1969 |
P-450 level and taurochenodeoxycholate 6 beta-hydroxylase system of rat liver microsomes.
Topics: Animals; Bile Acids and Salts; Carbon Isotopes; Cholestyramine Resin; Cytochromes; Depression, Chemical; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Stimulation, Chemical; Thyroxine | 1970 |
Differences in primary cellular factors influencing the metabolism and distribution of 3,5,3'-L-triiodothyronine and L-thyroxine.
Topics: Animals; Feces; Histocytochemistry; Iodine Radioisotopes; Liver; Metabolic Clearance Rate; Phenobarbital; Rats; Thyroxine; Triiodothyronine | 1970 |
Dissociation between thyroxine metabolism and hormonal action in phenobarbital-treated rats.
Topics: Animals; Drug Antagonism; Glycerolphosphate Dehydrogenase; Kidney; Male; Mitochondria; Mitochondria, Liver; Myocardium; Oxygen Consumption; Phenobarbital; Rats; Thyroidectomy; Thyroxine | 1971 |
Does bile acid secretion determine canalicular bile production in rats?
Topics: Animals; Bile; Bile Acids and Salts; Bile Ducts; Carbon Isotopes; Chromatography, Gas; Liver Circulation; Male; Phenobarbital; Pituitary Gland; Rats; Rheology; Thyroxine | 1971 |
Increased thyroxine turnover and thyroidal function after stimulation of hepatocellular binding of thyroxine by phenobarbital.
Topics: Animals; Bile; Blood Proteins; Chlordan; Iodine; Iodine Radioisotopes; Kidney; Liver; Male; Phenobarbital; Protein Binding; Rats; Thyroid Gland; Thyroidectomy; Thyroxine | 1968 |
Enhanced biliary excretion of thyroxine glucuronide in rats pretreated with benzpyrene.
Topics: Animals; Autoradiography; Benzopyrenes; Bile; Bile Ducts; Chromatography, Paper; Female; Glucuronates; Hexobarbital; In Vitro Techniques; Iodine Isotopes; Male; Phenobarbital; Phenols; Rats; Sex Factors; Stimulation, Chemical; Thyroxine; Transferases | 1968 |
Effect of phenobarbital administration on the subcellular distribution of 125-I-thyroxine in rat liver: mportance of microsomal binding.
Topics: Animals; Binding Sites; Body Weight; Cell Nucleus; Endoplasmic Reticulum; Iodine Isotopes; Liver; Male; Microsomes; Mitochondria, Liver; Organ Size; Phenobarbital; Rats; Stimulation, Chemical; Thyroxine | 1969 |
Effects of some substances on ergot alkaloid production.
Topics: Ascorbic Acid; Benz(a)Anthracenes; Benzopyrenes; Catalase; Culture Media; Ergot Alkaloids; Hydrocortisone; Oxygenases; Phenobarbital; Phenylalanine; Thyroxine; Tryptophan | 1969 |
Increased deiodination of L-thyroxine and L-triiodothyronine by liver microsomes from rats treated with phenobarbital.
Topics: Animals; Enzyme Induction; Iodine; Iodine Isotopes; Kinetics; Liver; Male; Microsomes; Monoiodotyrosine; Phenobarbital; Rats; Stimulation, Chemical; Thyroxine; Triiodothyronine | 1969 |
Tissue iodoprotein formation during the peripheral metabolism of the thyroid hormones.
Topics: Animals; Cell Nucleus; Iodine; Kidney; Kinetics; Liver; Male; Microsomes; Microsomes, Liver; Mitochondria; Mitochondria, Liver; Muscles; Myocardium; Phenobarbital; Protein Binding; Rats; Thyroxine; Triiodothyronine | 1969 |
Effect of drugs and hormones on rat liver dimethylaminoazobenzene reductase activity.
Topics: Allylisopropylacetamide; Amitrole; Animals; Cytochrome P-450 Enzyme System; Female; In Vitro Techniques; Methylcholanthrene; Microsomes, Liver; NADH, NADPH Oxidoreductases; p-Dimethylaminoazobenzene; Phenobarbital; Rats; Rats, Inbred Strains; Streptozocin; Thyroxine | 1982 |
[Effects of phenobarbital on thyroid function in childhood. Iatrogenic TBG deficiency].
Topics: Child; Child, Preschool; Female; Humans; Iatrogenic Disease; Infant; Male; Phenobarbital; Seizures, Febrile; Thyroid Gland; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine | 1984 |
[Direct and indirect parameters of free thyroxine. I. Method, quality control and in vitro experiments on storage of samples and effect of drugs].
Topics: Aspirin; Blood Preservation; Drug Interactions; Humans; Phenobarbital; Phenytoin; Primidone; Quality Control; Radioimmunoassay; Thyroxine | 1983 |
Heterogeneous distribution of the cytochrome P-450 monooxygenase system in rat liver lobes.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Fasting; Glucose; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Thyroxine | 1982 |
Combined hypothyroidism and hypoparathyroidism in an infant after maternal 131I administration.
Topics: Carcinoma; Female; Humans; Hypocalcemia; Hypoparathyroidism; Hypothyroidism; Infant; Infant, Newborn; Infant, Newborn, Diseases; Iodine Radioisotopes; Maternal-Fetal Exchange; Phenobarbital; Pregnancy; Pregnancy Trimester, First; Thyroid Neoplasms; Thyroxine; Trachea; Tracheotomy | 1981 |
Estrogen-2-hydroxylase in the rat. Distribution and response to hormonal manipulation.
Topics: Animals; Castration; Catechol O-Methyltransferase; Cytochrome P-450 CYP1A1; Enzyme Induction; Estrogens; Female; Hormones; Male; Methylcholanthrene; Phenobarbital; Rats; Steroid Hydroxylases; Thyroidectomy; Thyroxine | 1980 |
ELISA screening of monoclonal antibodies to haptens: influence of the chemical structure of hapten-protein conjugates.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Carrier Proteins; Cattle; Digoxin; Enzyme-Linked Immunosorbent Assay; Haptens; Hemocyanins; Hybridomas; Mice; Molecular Structure; Phenobarbital; Serum Albumin, Bovine; Theophylline; Thyroxine | 1994 |
The effects on rat thyroid function of an hepatic microsomal enzyme inducer.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Depression, Chemical; Enzyme Induction; Male; Microsomes, Liver; Mixed Function Oxygenases; Organ Size; Phenobarbital; Pituitary Gland; Rats; Rats, Inbred Strains; Thyroid Function Tests; Thyroid Gland; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine | 1993 |
[Neonatal Basedow's disease in twins from a mother with severe T3 hyperthyroidism].
Topics: Adrenergic beta-Antagonists; Adult; Antithyroid Agents; Autoantibodies; Developmental Disabilities; Diseases in Twins; Female; Fetal Blood; Graves Disease; Humans; Hypnotics and Sedatives; Infant, Newborn; Infectious Disease Transmission, Vertical; Iodide Peroxidase; Microcephaly; Phenobarbital; Pregnancy; Pregnancy Complications; Propranolol; Propylthiouracil; Receptors, Thyrotropin; Thyroxine; Triiodothyronine; Twins, Dizygotic | 1997 |
Short-term influence of prednisone and phenobarbital on thyroid function in euthyroid dogs.
Topics: Animals; Anti-Inflammatory Agents; Anticonvulsants; Dogs; Female; Male; Phenobarbital; Prednisone; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyroxine | 1999 |
Serum total thyroxine, total triiodothyronine, free thyroxine, and thyrotropin concentrations in epileptic dogs treated with anticonvulsants.
Topics: Animals; Anticonvulsants; Bromides; Dog Diseases; Dogs; Drug Therapy, Combination; Epilepsy; Female; Male; Phenobarbital; Potassium Compounds; Prospective Studies; Thyrotropin; Thyroxine; Triiodothyronine | 1999 |
Mimicry in primary rat hepatocyte cultures of the in vivo perivenous induction by phenobarbital of cytochrome P-450 2B1 mRNA: role of epidermal growth factor and perivenous oxygen tension.
Topics: Animals; Arteries; Cell Membrane; Chelating Agents; Cobalt; Cytochrome P-450 CYP2B1; Deferoxamine; Enzyme Induction; Enzyme Repression; Epidermal Growth Factor; ErbB Receptors; Gene Expression Regulation, Enzymologic; Growth Hormone; Heme; In Vitro Techniques; Liver; Male; Molecular Mimicry; Oxygen; Phenobarbital; Rats; Rats, Wistar; RNA, Messenger; Thyroxine | 1999 |
Effects of phenobarbital treatment on serum thyroxine and thyroid-stimulating hormone concentrations in epileptic dogs.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Anticonvulsants; Aspartate Aminotransferases; Bile Acids and Salts; Cholesterol; Cross-Sectional Studies; Dog Diseases; Dogs; Epilepsy; Female; gamma-Glutamyltransferase; Hypothalamo-Hypophyseal System; Immunoenzyme Techniques; Male; Phenobarbital; Seizures; Thyroid Gland; Thyrotropin; Thyroxine | 1999 |
Severe symptoms following a massive intentional L-thyroxine ingestion.
Topics: Adult; Antidotes; Body Weight; Charcoal; Diazepam; Haloperidol; Humans; Intubation, Intratracheal; Male; Phenobarbital; Propranolol; Tachycardia; Thyrotoxicosis; Thyroxine | 1999 |
Effects of microsomal enzyme inducers on thyroid-follicular cell proliferation, hyperplasia, and hypertrophy.
Topics: Animals; Cell Count; Cell Division; Chlorodiphenyl (54% Chlorine); Enzyme Activation; Hyperplasia; Hypertrophy; Male; Methylcholanthrene; Organ Size; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 1999 |
Long-term treatment of children with epilepsy with valproate or carbamazepine may cause subclinical hypothyroidism.
Topics: Adolescent; Age Factors; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Hypothyroidism; Male; Phenobarbital; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine; Valproic Acid | 1999 |
Differential effects of microsomal enzyme inducers on in vitro thyroxine (T(4)) and triiodothyronine (T(3)) glucuronidation.
Topics: Animals; Chlorodiphenyl (54% Chlorine); Detergents; Enzyme Induction; Glucuronides; Glucuronosyltransferase; In Vitro Techniques; Iodine Radioisotopes; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Thyroxine; Triiodothyronine | 2000 |
Thyroid hypertrophic effect of semotiadil fumarate, a new calcium antagonist, in rats.
Topics: Animals; Calcium Channel Blockers; Female; Glucuronosyltransferase; Hyperplasia; Hypertrophy; Liver; Microsomes, Liver; Nicardipine; Phenobarbital; Propylthiouracil; Rats; Rats, Wistar; Thiazoles; Thyroid Diseases; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 2000 |
Thyroid hyperactivity induced by methimazole, spironolactone and phenobarbital in marmosets (Callithrix jacchus): histopathology, plasma thyroid hormone levels and hepatic T4 metabolism.
Topics: Animals; Anticonvulsants; Antithyroid Agents; Biopsy; Callithrix; Cytochrome P-450 Enzyme System; Immunohistochemistry; Liver; Male; Methimazole; Microscopy, Electron; Mineralocorticoid Receptor Antagonists; Phenobarbital; Radioimmunoassay; Spironolactone; Thyroid Diseases; Thyroid Gland; Thyroxine; Triiodothyronine | 2000 |
Changes in serum thyroxine and thyroid-stimulating hormone concentrations in epileptic dogs receiving phenobarbital for one year.
Topics: Analysis of Variance; Animals; Anticonvulsants; Dog Diseases; Dogs; Epilepsy; Female; Male; Phenobarbital; Prospective Studies; Thyrotropin; Thyroxine | 2000 |
Evaluation of the male pubertal assay's ability to detect thyroid inhibitors and dopaminergic agents.
Topics: Animals; Antithyroid Agents; Body Weight; Bromocriptine; Dopamine Agonists; Dopamine Antagonists; Genitalia, Male; Haloperidol; Liver; Male; Organ Size; Phenobarbital; Propylthiouracil; Rats; Rats, Sprague-Dawley; Sexual Maturation; Thyroid Gland; Thyrotropin; Thyroxine | 2001 |
Synergistic effects of high-dose soybean intake with iodine deficiency, but not sulfadimethoxine or phenobarbital, on rat thyroid proliferation.
Topics: Animals; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Female; Glycine max; Hyperplasia; Iodine; Phenobarbital; Rats; Rats, Inbred F344; Sulfadimethoxine; Thyroid Gland; Thyroid Neoplasms; Thyrotropin; Thyroxine; Triiodothyronine | 2001 |
[On modification of the effect of thyroxin by various neuroplegics].
Topics: Chlorpromazine; Meprobamate; Phenobarbital; Reserpine; Thyroxine | 1961 |
Enhanced rat Hershberger assay appears reliable for detection of not only (anti-)androgenic chemicals but also thyroid hormone modulators.
Topics: Administration, Oral; Androgen Antagonists; Animals; Antithyroid Agents; Body Weight; Castration; Dichlorodiphenyl Dichloroethylene; Drug Evaluation, Preclinical; Eating; Injections, Subcutaneous; Male; Organ Size; Phenobarbital; Propylthiouracil; Rats; Rats, Inbred Strains; Reproducibility of Results; Testosterone Propionate; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 2004 |
Role of the constitutive androstane receptor in xenobiotic-induced thyroid hormone metabolism.
Topics: Animals; Anticonvulsants; Blotting, Northern; Cell Proliferation; Constitutive Androstane Receptor; Dose-Response Relationship, Drug; Female; Humans; Immunohistochemistry; Male; Mice; Models, Biological; Mutation; Phenobarbital; Proliferating Cell Nuclear Antigen; Propylthiouracil; Pyridines; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Thyroid Hormones; Thyroid Neoplasms; Thyroxine; Transcription Factors; Triiodothyronine; Xenobiotics | 2005 |
Decrease in serum thyroxine level by phenobarbital in rats is not necessarily dependent on increase in hepatic UDP-glucuronosyltransferase.
Topics: Animals; Anticonvulsants; Enzyme Induction; Glucuronosyltransferase; Iodide Peroxidase; Liver; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Gunn; Rats, Wistar; Thyroxine; Triiodothyronine | 2005 |
[Effect of phenobarbital and thyroxine on hepatocarcinogenesis initiated in mice by nitrosoethylurea and diethylnitrosamine].
Topics: Alkylating Agents; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Ethylnitrosourea; Female; Hypnotics and Sedatives; Leukemia; Lung Neoplasms; Male; Mice; Mice, Inbred CBA; Mice, Inbred ICR; Phenobarbital; Thyroxine | 2005 |
Standardization of the perchlorate discharge assay for thyroid toxicity testing in rats.
Topics: Animals; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Hyperplasia; Hypertrophy; Iodine Radioisotopes; Male; Perchlorates; Phenobarbital; Potassium Compounds; Potassium Iodide; Propylthiouracil; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyroxine; Toxicity Tests; Triiodothyronine | 2007 |
Biotransformation of brominated flame retardants into potentially endocrine-disrupting metabolites, with special attention to 2,2',4,4'-tetrabromodiphenyl ether (BDE-47).
Topics: Animals; Binding, Competitive; Cell Division; Cytochrome P-450 Enzyme System; Endocrine Disruptors; Enzyme Inhibitors; Estradiol; Flame Retardants; Halogenated Diphenyl Ethers; Hydroxylation; Male; Microsomes, Liver; NADP; Phenobarbital; Polybrominated Biphenyls; Prealbumin; Rats; Rats, Wistar; Sulfotransferases; Thyroxine | 2008 |
Synergistic acceleration of thyroid hormone degradation by phenobarbital and the PPAR alpha agonist WY14643 in rat hepatocytes.
Topics: Animals; Cells, Cultured; Drug Synergism; Hepatocytes; Male; Phenobarbital; PPAR alpha; Pyrimidines; Rats; Rats, Wistar; Thyroxine; Triiodothyronine | 2009 |
A possible mechanism for the decrease in serum thyroxine level by phenobarbital in rodents.
Topics: Animals; Cricetinae; Glucuronides; Guinea Pigs; Hypnotics and Sedatives; Liver; Male; Mice; Phenobarbital; Rats; Rats, Wistar; Sulfotransferases; Thyroxine; Triiodothyronine | 2010 |
Thyroid status in a large cohort of patients with mental retardation: the TOP-R (Thyroid Origin of Psychomotor Retardation) study.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Cohort Studies; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Hyperthyroidism; Hypothyroidism; Intellectual Disability; Lamotrigine; Linear Models; Male; Middle Aged; Netherlands; Phenobarbital; Phenytoin; Prevalence; Thyroid Gland; Thyrotropin; Thyroxine; Triazines; Triiodothyronine; Valproic Acid | 2011 |
Hypothyroidism caused by phenobarbital affects patterns of estrous cyclicity in rats.
Topics: Animals; Estradiol; Estrous Cycle; Female; Hypothyroidism; Ovary; Phenobarbital; Progesterone; Prolactin; Rats; Thyrotropin; Thyroxine; Triiodothyronine | 2011 |