phenobarbital has been researched along with thiophenes in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (16.67) | 18.7374 |
| 1990's | 6 (33.33) | 18.2507 |
| 2000's | 7 (38.89) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duffy, EM; Jorgensen, WL | 1 |
| Nakayama, S | 1 |
| Amar, C; Dansette, PM; Mansuy, D; Pons, C; Smith, C | 1 |
| Hirayama, Y; Katagiri, K; Katsuta, Y; Kurata, R; Matsushima, K; Nakamichi, K; Tsuchida, S; Yamaki, T; Yano, M | 1 |
| Kasich, AM | 1 |
| Coles, B; Gilmore, KS; Guengerich, FP; Harris, J; Harris, TM; Kensler, TW; Ketterer, B; Meyer, DJ; Raney, K | 1 |
| Fardel, O; Gilmore, KS; Guillouzo, A; Kensler, TW; Ketterer, B; Langouet, S; Meunier, B; Meyer, DJ; Morel, F; Tu, CP | 1 |
| Ellis, EM; Hayes, JD; Judah, DJ; Neal, GE; O'Connor, T | 1 |
| Corcos, L; Fardel, O; Guillouzo, A; Ketterer, B; Langouët, S; Meyer, DJ; Morel, F | 1 |
| de Sousa, G; Guillouzo, A; Langouët, S; Lorenzon, G; Nicolas, F; Placidi, M; Rahmani, R | 1 |
| Cherrington, NJ; Klaassen, CD; Maher, JM; Slitt, AL | 1 |
| Bae, SK; Kim, T; Kim, YH; Lee, MG; Lee, SJ | 1 |
| Boursier-Neyret, C; Fardel, O; Jigorel, E; Le Vee, M; Parmentier, Y | 1 |
| Beilke, LD; Besselsen, DG; Cheng, Q; Cherrington, NJ; Kulkarni, S; Slitt, AL | 1 |
| Aleksunes, LM; Beilke, LD; Besselsen, DG; Cherrington, NJ; Dvorak, K; Klaassen, CD; Olson, ER | 1 |
| Grubbs, CJ; Lubet, RA; Wang, Y; Yao, R; You, M | 1 |
| Droździk, A; Laszczyńska, M; Wajda, A; Łapczuk, J | 1 |
| Supuran, CT | 1 |
1 review(s) available for phenobarbital and thiophenes
| Article | Year |
|---|---|
Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors.
Topics: Acetazolamide; Anti-Inflammatory Agents, Non-Steroidal; Anti-Obesity Agents; Antibodies, Monoclonal; Anticonvulsants; Antineoplastic Agents; Benzodiazepines; Carbonic Anhydrase Inhibitors; Celecoxib; Clinical Trials as Topic; Contraindications; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Fructose; Humans; Isoxazoles; Methazolamide; Phenobarbital; Sulfanilamide; Sulfanilamides; Sulfonamides; Sulfonic Acids; Thiazines; Thiophenes; Topiramate; Zonisamide | 2016 |
1 trial(s) available for phenobarbital and thiophenes
| Article | Year |
|---|---|
A double-blind study of heteronium bromide and amobarbital in the management of gastrointestinal conditions associated with anxiety.
Topics: Adult; Aged; Amobarbital; Anxiety; Clinical Trials as Topic; Colonic Diseases, Functional; Duodenal Ulcer; Female; Gastrointestinal Motility; Humans; Male; Middle Aged; Peptic Ulcer; Phenobarbital; Placebos; Propantheline; Psychophysiologic Disorders; Pyrrolidines; Thiophenes | 1968 |
16 other study(ies) available for phenobarbital and thiophenes
| Article | Year |
|---|---|
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
[Effects of diispropyl 1, 3-dithiol-2-ylidene malonate (NKK-105) on the drug-metabolizing enzymes and fine structure of rat liver (author's transl)].
Topics: Aminopyrine N-Demethylase; Animals; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Ethionine; Lipid Peroxides; Liver; Male; Malonates; Microscopy, Electron; Microsomes, Liver; Mitochondria, Liver; Organ Size; Phenobarbital; Rats; Thiophenes | 1979 |
Oxidative activation of the thiophene ring by hepatic enzymes. Hydroxylation and formation of electrophilic metabolites during metabolism of tienilic acid and its isomer by rat liver microsomes.
Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Glycolates; Hydroxylation; Isomerism; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Phenobarbital; Protein Binding; Rats; Rats, Inbred Strains; Thiophenes; Ticrynafen | 1990 |
Stimulation of rat liver growth by a 1,3-dithiole derivative, KZ-1026.
Topics: Animals; Cell Nucleus; DNA; Galactose; Hepatectomy; Ketones; Liver; Liver Function Tests; Male; Phenobarbital; Rats; Rats, Inbred Strains; Thiophenes; Thymidine | 1989 |
Induction of rat liver GSH transferases by 1,2-dithiole-3-thione illustrates both anticarcinogenic and tumor-promoting properties.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Carcinogens; Chromatography, Affinity; Chromatography, High Pressure Liquid; Cytosol; Enzyme Induction; Glutathione Transferase; Inactivation, Metabolic; Liver; Macromolecular Substances; Phenobarbital; Rats; Rats, Sprague-Dawley; Thiones; Thiophenes | 1993 |
Preferential increase of glutathione S-transferase class alpha transcripts in cultured human hepatocytes by phenobarbital, 3-methylcholanthrene, and dithiolethiones.
Topics: Cells, Cultured; Enzyme Induction; Gene Expression; Glutathione Transferase; Humans; Liver; Methylcholanthrene; Phenobarbital; Pyrazines; RNA, Messenger; Thiones; Thiophenes | 1993 |
Regulation of carbonyl-reducing enzymes in rat liver by chemoprotectors.
Topics: Aldehyde Reductase; Animals; Antioxidants; Barbiturates; Butylated Hydroxyanisole; Carcinogens; Enzyme Induction; Ethoxyquin; Liver; Methylcholanthrene; Oxidation-Reduction; Phenobarbital; Pyrazines; Rats; Thiones; Thiophenes | 1996 |
A comparison of the effect of inducers on the expression of glutathione-S-transferases in the liver of the intact rat and in hepatocytes in primary culture.
Topics: Animals; Cells, Cultured; Enzyme Induction; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Liver; Male; Methylcholanthrene; Phenobarbital; Pyrazines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thiones; Thiophenes | 1996 |
Increase of cytochrome P-450 1A and glutathione transferase transcripts in cultured hepatocytes from dogs, monkeys, and humans after cryopreservation.
Topics: Animals; Cell Survival; Cells, Cultured; Cryopreservation; Cyclopentanes; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Dogs; Glutathione Transferase; Haplorhini; Humans; Liver; Phenobarbital; Pyrazines; RNA, Messenger; Thiones; Thiophenes | 1996 |
Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites.
Topics: Acetaminophen; Allyl Compounds; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Bile; Blotting, Western; Branched DNA Signal Amplification Assay; Drug Resistance, Multiple; Kidney; Liver; Male; Mitochondrial Proteins; Phenobarbital; Pyrazines; Rats; Rats, Sprague-Dawley; Ribosomal Proteins; RNA, Messenger; Saccharomyces cerevisiae Proteins; Stilbenes; Sulfides; Thiones; Thiophenes; Time Factors | 2003 |
Effect of enzyme inducers and inhibitors on the pharmacokinetics of oltipraz in rats.
Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Isoenzymes; Isoniazid; Male; Metabolic Clearance Rate; Methylcholanthrene; Microsomes, Liver; Models, Animal; Phenobarbital; Pyrazines; Rats; Rats, Sprague-Dawley; Thiones; Thiophenes | 2005 |
Differential regulation of sinusoidal and canalicular hepatic drug transporter expression by xenobiotics activating drug-sensing receptors in primary human hepatocytes.
Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Constitutive Androstane Receptor; Gene Expression Regulation; Hepatocytes; Humans; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; NF-E2-Related Factor 2; Phenobarbital; Polychlorinated Dibenzodioxins; Pregnane X Receptor; Pyrazines; Receptors, Aryl Hydrocarbon; Receptors, Cytoplasmic and Nuclear; Receptors, Drug; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; Rifampin; RNA, Messenger; Symporters; Thiones; Thiophenes; Transcription Factors; Xenobiotics | 2006 |
Minimal role of hepatic transporters in the hepatoprotection against LCA-induced intrahepatic cholestasis.
Topics: Animals; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cholestasis, Intrahepatic; Cytoprotection; Disease Models, Animal; Lithocholic Acid; Liver; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Organic Anion Transporters, Sodium-Dependent; Phenobarbital; Protective Agents; Pyrazines; Pyridines; RNA, Messenger; Symporters; Thiones; Thiophenes; Time Factors; Up-Regulation | 2008 |
Decreased apoptosis during CAR-mediated hepatoprotection against lithocholic acid-induced liver injury in mice.
Topics: Animals; Apoptosis; bcl-X Protein; Caspase 3; Cholestasis, Intrahepatic; Constitutive Androstane Receptor; Cytoprotection; Disease Models, Animal; Lithocholic Acid; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Cell Leukemia Sequence 1 Protein; Phenobarbital; Pregnenolone Carbonitrile; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Pyridines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiones; Thiophenes; Transcription Factors | 2009 |
Induced expression of drug metabolizing enzymes by preventive agents: role of the antioxidant response element.
Topics: Allyl Compounds; Animals; Anticarcinogenic Agents; Antioxidants; beta-Naphthoflavone; Enzyme Induction; Ethoxyquin; Female; Gene Expression Regulation; Glutathione Transferase; Liver; NAD(P)H Dehydrogenase (Quinone); Oligonucleotide Array Sequence Analysis; Phenobarbital; Rats; Rats, Sprague-Dawley; Response Elements; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfhydryl Compounds; Sulfides; Thiones; Thiophenes | 2009 |
Expression and functional regulation of the nuclear receptors AHR, PXR, and CAR, and the transcription factor Nrf2 in rat parotid gland.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Nucleus; Constitutive Androstane Receptor; Cytoplasm; Dexamethasone; Gene Expression Regulation; Male; NF-E2-Related Factor 2; Parotid Gland; Phenobarbital; Polychlorinated Dibenzodioxins; Pregnane X Receptor; Pyrazines; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Salivary Ducts; Thiones; Thiophenes | 2014 |