phenobarbital and stilbenes

phenobarbital has been researched along with stilbenes in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199029 (74.36)18.7374
1990's5 (12.82)18.2507
2000's3 (7.69)29.6817
2010's2 (5.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Elmamlouk, TH; Mukhtar, H1
Guengerich, FP; Mason, PS; Mitchell, MB; Wang, P1
Miyazaki, S1
Di Simplicio, P; Jensson, H; Mannervik, B1
Gregus, Z; Klaassen, CD; Madhu, C1
Ashley, PJ; Finley, BL; Neptune, AG; Yost, GS1
Beland, FA; Djurić, Z; Fifer, EK; Howard, PC1
Duke, CC; Gill, JH; Holder, GM; Ryan, AJ1
Hayashi, S; McManus, ME; Razzouk, C; Schwartz, D; Thorgeirsson, SS1
Gregus, Z; Varga, F1
Hook, JB; Kuo, CH1
Gielen, JE; Goujon, FM; Van Cantfort, J1
Hilpert, D; Neumann, HG1
Kalinyak, JE; Taylor, JM1
Baron, J; Guengerich, FP; Kawabata, TT1
Lu, AY; Pickett, CB; Wang, R; Williams, JB1
DePierre, JW; Guengerich, FP; Meijer, J; Wang, PP1
Aström, A; Balk, L; DePierre, JW; Ernster, L; Meijer, J; Morgenstern, R; Norélius, I; Seidegård, J1
Bellward, GD; Gontovnick, LS; Sunahara, G1
Aström, A; Balk, L; DePierre, JW; Meijer, J; Morgenstern, R; Seidegård, J1
Bock, KW; Lilienblum, W; Walli, AK1
Gonzalez, FJ; Kasper, CB1
DePierre, JW; Meijer, J3
Steggles, AW; Vlasuk, GP; Walz, FG1
Levin, W; Ryan, DE; Thomas, PE; Vlasuk, GP; Walz, FG1
Bellward, GD; Gontovnick, LS1
Carlberg, I; Depierre, JW; Mannervik, B1
Hammerl, R; Kirchner, T; Neumann, HG1
Blacker, KL; Boyer, TD; Lee, KH; Vessey, DA1
Funae, Y; Imaoka, S; Kaneko, E; Kaneko, Y; Mikami, T; Numazawa, S; Oguro, T; Yoshida, T1
Bitsch, A; Duebelbeiss, C; Greiner, A1
Acharya, C; Andersen, MR; Omiecinski, CJ; Schilter, B1
Cherrington, NJ; Klaassen, CD; Maher, JM; Slitt, AL1
BRAUN, J; MUELLER, WA1
Bishayee, A; Dhir, N1
Barnes, KF; Bhatia, D; Bishayee, A; Carroll, RT; Darvesh, AS1
Awale, P; Bhatia, D; Bishayee, A; Carroll, RT; Darvesh, AS; Geldenhuys, WJ; Mbimba, T1

Other Studies

39 other study(ies) available for phenobarbital and stilbenes

ArticleYear
trans-Stilbene oxide: a new inducer of rat liver microsomal UDP-glucuronyltransferase.
    Biochemical pharmacology, 1979, Volume: 28, Issue:4

    Topics: Animals; Enzyme Induction; Glucuronosyltransferase; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Nitrophenols; Phenobarbital; Rats; Stilbenes

1979
Rat and human liver microsomal epoxide hydratase. Purification and evidence for the existence of multiple forms.
    The Journal of biological chemistry, 1979, Dec-10, Volume: 254, Issue:23

    Topics: Amino Acids; Animals; Epoxide Hydrolases; Humans; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Molecular Weight; Phenobarbital; Rats; Stilbenes

1979
Effect of chemicals on glutathione peroxidase of chick liver.
    Research in veterinary science, 1991, Volume: 51, Issue:1

    Topics: Animals; Benzene Derivatives; Butylated Hydroxyanisole; Chickens; Chromatography, Gel; Clofibrate; Glutathione Peroxidase; Hydrogen Peroxide; Liver; Male; Methylcholanthrene; Phenobarbital; Stilbenes

1991
Effects of inducers of drug metabolism on basic hepatic forms of mouse glutathione transferase.
    The Biochemical journal, 1989, Nov-01, Volume: 263, Issue:3

    Topics: Animals; Butylated Hydroxyanisole; Cytosol; Diterpenes; Enzyme Induction; Glutaredoxins; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Isoenzymes; Lactoylglutathione Lyase; Liver; Methylcholanthrene; Mice; Organ Size; Oxidoreductases; Phenobarbital; Protein Disulfide Reductase (Glutathione); Stilbenes

1989
Inducibility of glutathione S-transferases in hamsters.
    Cancer letters, 1989, Volume: 44, Issue:2

    Topics: Animals; Butylated Hydroxyanisole; Cats; Cricetinae; Dexamethasone; Dogs; Enzyme Induction; Ethanol; Glutathione Transferase; Guinea Pigs; Isoniazid; Liver; Male; Mesocricetus; Methylcholanthrene; Mice; Phenobarbital; Polychlorinated Dibenzodioxins; Pregnenolone Carbonitrile; Quail; Rabbits; Rats; Species Specificity; Stilbenes; Trout

1989
Substrate-selective induction of rabbit hepatic UDP-glucuronyltransferases by ethanol and other xenobiotics.
    Biochemical pharmacology, 1986, Sep-01, Volume: 35, Issue:17

    Topics: Animals; Energy Intake; Enzyme Induction; Estrone; Ethanol; Glucuronosyltransferase; Male; Microsomes, Liver; Phenobarbital; Rabbits; Stilbenes; Substrate Specificity

1986
Oxidative microsomal metabolism of 1-nitropyrene and DNA-binding of oxidized metabolites following nitroreduction.
    Carcinogenesis, 1986, Volume: 7, Issue:7

    Topics: Acetylation; Animals; Aroclors; Chlorodiphenyl (54% Chlorine); Chromatography, High Pressure Liquid; DNA; Hydroxylation; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Pyrenes; Rats; Rats, Inbred Strains; Stilbenes; Xanthine Oxidase

1986
Dibenz [a,j]acridine: distributions of metabolites formed by liver and lung microsomes from control and pretreated rats.
    Carcinogenesis, 1987, Volume: 8, Issue:3

    Topics: Acridines; Animals; Biotransformation; Lung; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Stilbenes

1987
Induction of epoxide hydrolase in cultured rat hepatocytes and hepatoma cell lines.
    Biochemical pharmacology, 1985, May-01, Volume: 34, Issue:9

    Topics: 2-Acetylaminofluorene; Animals; Cells, Cultured; Enzyme Induction; Epoxide Hydrolases; Hydroxyacetylaminofluorene; Liver; Liver Neoplasms, Experimental; Male; Phenobarbital; Rats; Rats, Inbred Strains; Stilbenes

1985
Role of glutathione and hepatic glutathione S-transferase in the biliary excretion of methyl mercury, cadmium and zinc: a study with enzyme inducers and glutathione depletors.
    Acta pharmacologica et toxicologica, 1985, Volume: 56, Issue:5

    Topics: Animals; Bile; Cadmium; Enzyme Induction; Glutathione; Glutathione Transferase; Liver; Male; Methylmercury Compounds; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Stilbenes; Zinc

1985
Effects of drug-metabolizing enzyme inducers on cephaloridine toxicity in Fischer 344 rats.
    Toxicology, 1982, Volume: 24, Issue:3-4

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cephaloridine; Drug Interactions; Enzyme Induction; Kidney; Phenobarbital; Piperonyl Butoxide; Polybrominated Biphenyls; Rabbits; Rats; Rats, Inbred F344; Rats, Inbred Strains; Stilbenes

1982
Comparison of aryl hydrocarbon hydroxylase and epoxide hydratase. Induction in primary fetal rat liver cell culture.
    Chemico-biological interactions, 1980, Volume: 31, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Cells, Cultured; Cycloheximide; Dactinomycin; DNA; Enzyme Induction; Epoxide Hydrolases; Kinetics; Liver; Nicotiana; Phenobarbital; Plants, Toxic; Polychlorinated Dibenzodioxins; Protein Biosynthesis; Rats; RNA; Smoke; Stilbenes

1980
The effects of partial hepatectomy and of promoters on macromolecular binding of trans-4-acetylaminostilbene metabolites in liver and some extrahepatic tissues of rats.
    Carcinogenesis, 1983, Volume: 4, Issue:12

    Topics: Animals; Biotransformation; Carcinogens; Female; Gastric Mucosa; Kidney; Kinetics; Liver; Liver Regeneration; Lung; Phenobarbital; Protein Binding; Proteins; Rats; Rats, Inbred Strains; RNA; Stilbenes; Tissue Distribution; Tritium

1983
Rat glutathione S-transferase. Cloning of double-stranded cDNA and induction of its mRNA.
    The Journal of biological chemistry, 1982, Jan-10, Volume: 257, Issue:1

    Topics: Animals; Base Sequence; Cloning, Molecular; DNA Restriction Enzymes; DNA, Recombinant; Glutathione Transferase; Liver; Male; Molecular Weight; Nucleic Acid Hybridization; Phenobarbital; Plasmids; Rats; Rats, Inbred Strains; RNA, Messenger; Stilbenes; Transcription, Genetic

1982
Effects of phenobarbital, trans-stilbene oxide, and 3-methylcholanthrene on epoxide hydrolase within centrilobular, midzonal, and periportal regions of rat liver.
    The Journal of biological chemistry, 1983, Jun-25, Volume: 258, Issue:12

    Topics: Animals; Epoxide Hydrolases; Fluorescent Antibody Technique; Histocytochemistry; Male; Methylcholanthrene; Microsomes, Liver; Organ Specificity; Phenobarbital; Rats; Stilbenes

1983
Rat liver DT-diaphorase: regulation of functional mRNA levels by 3-methylcholanthrene, trans-stilbene oxide, and phenobarbital.
    Archives of biochemistry and biophysics, 1984, Volume: 232, Issue:1

    Topics: Animals; Cell-Free System; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Immunochemistry; Liver; Methylcholanthrene; NAD(P)H Dehydrogenase (Quinone); NADH, NADPH Oxidoreductases; Phenobarbital; Quinone Reductases; Rabbits; Rats; RNA, Messenger; Stilbenes

1984
Purification and characterization of the major microsomal cytochrome P-450 form induced by trans-stilbene oxide in rat liver.
    Biochimica et biophysica acta, 1984, Aug-28, Volume: 789, Issue:1

    Topics: Amino Acids; Animals; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Immunodiffusion; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Molecular Weight; Phenobarbital; Rats; Rats, Inbred Strains; Stilbenes

1984
Induction of cytosolic glutathione transferase and microsomal epoxide hydrolase activities in extrahepatic organs of the rat by phenobarbital, 3-methylcholanthrene and trans-stilbene oxide.
    Xenobiotica; the fate of foreign compounds in biological systems, 1984, Volume: 14, Issue:4

    Topics: Animals; Cytosol; Epoxide Hydrolases; Glutathione Transferase; Male; Methylcholanthrene; Microsomes; Phenobarbital; Rats; Rats, Inbred Strains; Stilbenes; Time Factors; Tissue Distribution

1984
Nonadditive effects of combined in vivo hepatic microsomal enzyme inducers in the Wistar rat.
    Canadian journal of physiology and pharmacology, 1983, Volume: 61, Issue:9

    Topics: Animals; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Female; Methylcholanthrene; Microsomes, Liver; Oxygenases; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Spironolactone; Stilbenes

1983
Induction of xenobiotic-metabolizing enzymes by trans-stilbene oxide and 2-acetylaminofluorene: observations on enzyme induction by drugs.
    Biochemical Society transactions, 1984, Volume: 12, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Enzyme Induction; Enzymes; Liver; Male; Methylcholanthrene; Pharmaceutical Preparations; Phenobarbital; Rats; Stilbenes

1984
Differential induction of rat liver microsomal UDP-glucuronosyltransferase activites by various inducing agents.
    Biochemical pharmacology, 1982, Mar-15, Volume: 31, Issue:6

    Topics: Animals; Aroclors; Benzoflavones; Benzopyrene Hydroxylase; Benzopyrenes; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Clofibric Acid; DDT; Enzyme Induction; Glucuronosyltransferase; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Stilbenes

1982
Differential inducibility of nuclear envelope epoxide hydratase by trans-stilbene oxide and phenobarbital.
    Molecular pharmacology, 1982, Volume: 21, Issue:2

    Topics: Animals; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes; Enzyme Induction; Epoxide Hydrolases; Glucuronosyltransferase; Immunochemistry; Male; NADPH-Ferrihemoprotein Reductase; Nuclear Envelope; Phenobarbital; Rats; Rats, Inbred Strains; Stilbenes

1982
Comparison of trans-stilbene oxide, phenobarbital and 3-methylcholanthrene as inducers of steroid metabolism by the rat liver microsomal cytochrome P-450 system.
    Journal of steroid biochemistry, 1983, Volume: 18, Issue:4

    Topics: Androstenedione; Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Hydroxylation; Kinetics; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Stilbenes; Testosterone

1983
Species differences in cytochromes P-450 and epoxide hydrolase: comparisons of xenobiotic-induced hepatic microsomal polypeptides in hamsters and rats.
    Biochemistry, 1983, Mar-29, Volume: 22, Issue:7

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cricetinae; Cytochrome P-450 Enzyme System; Enzyme Induction; Epoxide Hydrolases; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Pregnenolone Carbonitrile; Rats; Species Specificity; Stilbenes

1983
Polypeptide patterns of hepatic microsomes from Long-Evans rats treated with different xenobiotics.
    Biochemistry, 1982, Nov-23, Volume: 21, Issue:24

    Topics: Animals; Aroclors; Chlordan; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Isomerism; Male; Methylcholanthrene; Microsomes, Liver; Peptide Biosynthesis; Phenobarbital; Pregnenolone Carbonitrile; Proadifen; Rats; Safrole; Stilbenes

1982
Sex and age dependence of the "selective" induction of rat hepatic microsomal epoxide hydratase following trans-stilbene oxide, l-alpha-acetylmethadol, or phenobarbital treatment.
    Biochemical pharmacology, 1980, Volume: 29, Issue:24

    Topics: Age Factors; Animals; Benzopyrene Hydroxylase; Enzyme Induction; Epoxide Hydrolases; Female; Male; Methadone; Methadyl Acetate; Microsomes, Liver; Phenobarbital; Rats; Sex Factors; Stilbenes

1980
Changes in the matabolism of steroid hormones by the rat liver cytochrome P-450 system after induction with trans-stilbene oxide.
    Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 1981, Volume: 35, Issue:2

    Topics: Androstenedione; Animals; Cytochrome P-450 Enzyme System; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Stilbenes; Testosterone

1981
Effect of inducers of drug-metabolizing enzymes on glutathione reductase and glutathione peroxidase in rat liver.
    Biochimica et biophysica acta, 1981, Sep-18, Volume: 677, Issue:1

    Topics: Animals; Cytosol; Enzyme Induction; Glutathione Peroxidase; Glutathione Reductase; Liver; Methylcholanthrene; Peroxidases; Phenobarbital; Rats; Stilbenes

1981
Characterization of the cytochrome P-450 species induced by trans-stilbene oxide.
    Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 1980, Volume: 34, Issue:3

    Topics: Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Stilbenes; Substrate Specificity

1980
Synergistic effects of trans-4-acetylaminostilbene and 2-acetylaminofluorene at the level of tumor initiation.
    Chemico-biological interactions, 1994, Volume: 93, Issue:1

    Topics: 2-Acetylaminofluorene; Aging; Animals; Biomarkers, Tumor; Carcinogens; Drug Synergism; Female; gamma-Glutamyltransferase; Glutathione Transferase; Hepatectomy; Liver; Liver Neoplasms; Male; Phenobarbital; Precancerous Conditions; Rats; Rats, Wistar; Sex Factors; Stilbenes; Time Factors

1994
Effect of inducers on the activity of glutathione S-transferase and other enzymes of the glutathione pathway in cultured human keratinocytes.
    Skin pharmacology : the official journal of the Skin Pharmacology Society, 1993, Volume: 6, Issue:4

    Topics: Butylated Hydroxyanisole; Cells, Cultured; Enzyme Induction; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Humans; Keratinocytes; Phenobarbital; Propylthiouracil; Stilbenes

1993
Suppressed expression of phenobarbital-inducible hepatic cytochrome P-450s in Eisai-hyperbilirubinuria rats (EHBR/Eis).
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:3

    Topics: Animals; Cytochrome P-450 Enzyme System; Hyperbilirubinemia; Immunoblotting; Liver; Male; Microsomes; Phenobarbital; Rats; Stilbenes; Time Factors

1996
c-fos gene expression in rat liver is induced by phenobarbital.
    Cancer letters, 1999, Jan-29, Volume: 135, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Gene Expression; Genes, fos; Liver; Liver Neoplasms, Experimental; Phenobarbital; Proto-Oncogene Proteins c-fos; Random Allocation; Rats; Rats, Wistar; RNA, Messenger; Stilbenes

1999
Activation of cytochrome P450 gene expression in the rat brain by phenobarbital-like inducers.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:3

    Topics: Allyl Compounds; Amitriptyline; Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Northern; Brain; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DDT; Enzyme Induction; Epoxide Hydrolases; Liver; Male; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Steroid Hydroxylases; Stilbenes; Sulfides

2000
Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:9

    Topics: Acetaminophen; Allyl Compounds; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Bile; Blotting, Western; Branched DNA Signal Amplification Assay; Drug Resistance, Multiple; Kidney; Liver; Male; Mitochondrial Proteins; Phenobarbital; Pyrazines; Rats; Rats, Sprague-Dawley; Ribosomal Proteins; RNA, Messenger; Saccharomyces cerevisiae Proteins; Stilbenes; Sulfides; Thiones; Thiophenes; Time Factors

2003
[THE DIFFERENT FORMS OF EXPERIMENTAL VENTRICULAR ULCER IN RATS AND THEIR MEDICAL CONTROL. 3. INDUCTION OF GASTRIC GLAND ULCERS IN RATS BY IMMOBILIZATION OF THE ANIMAL. OBSERVATION ON UROPEPSINOGEN EXCRETION AND ITS CONTROL BY DRUGS].
    Arzneimittel-Forschung, 1964, Volume: 14

    Topics: Acetazolamide; Animals; Bis-Trimethylammonium Compounds; Endopeptidases; Enzyme Precursors; Gastric Mucosa; Immobilization; Pepsinogen A; Pharmacology; Phenobarbital; Rats; Research; Stilbenes; Stomach Ulcer; Strychnos nux-vomica; Ulcer

1964
Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosis.
    Chemico-biological interactions, 2009, May-15, Volume: 179, Issue:2-3

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Body Weight; Cell Proliferation; Diethylnitrosamine; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking; Drug Screening Assays, Antitumor; Eating; Female; Immunohistochemistry; Liver Neoplasms, Experimental; Organ Size; Phenobarbital; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes

2009
Resveratrol suppresses oxidative stress and inflammatory response in diethylnitrosamine-initiated rat hepatocarcinogenesis.
    Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:6

    Topics: Animals; Antioxidants; Carcinogens; Chemical and Drug Induced Liver Injury; Diethylnitrosamine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Induction; Female; Hyperplasia; Inflammation; Lipid Peroxidation; Liver; Liver Neoplasms, Experimental; NF-E2-Related Factor 2; Nitric Oxide Synthase Type II; Oxidative Stress; Phenobarbital; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes; Tyrosine

2010
Alteration of hepatic proinflammatory cytokines is involved in the resveratrol-mediated chemoprevention of chemically-induced hepatocarcinogenesis.
    Current pharmaceutical biotechnology, 2012, Volume: 13, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Cytokines; Diethylnitrosamine; Female; Gene Expression Regulation; Liver; Liver Neoplasms, Experimental; Phenobarbital; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes

2012