phenobarbital and quercetin

phenobarbital has been researched along with quercetin in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19903 (15.00)18.7374
1990's5 (25.00)18.2507
2000's8 (40.00)29.6817
2010's4 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Mangoura, SA; Maser, E; Netter, KJ; Oppermann, UC1
Ansari, NH; Bhatnagar, A; Das, B; Liu, SQ; Srivastava, SK1
Denda, A; Eimoto, H; Kinugasa, T; Kitazawa, S; Konishi, Y; Takashima, Y; Tsujiuchi, T; Tsutsumi, M; Ura, H1
Häfele, F; Krüger, A; Schimmer, O1
Fujii, M; Hirono, I; Kato, K; Kawai, T; Mori, H; Nishikawa, A; Takahashi, M; Tanaka, T1
Amanuma, T; Denda, A; Konishi, Y; Maruyama, H; Murata, Y; Tang, Q; Tsujiuchi, T; Tsutsumi, M1
Akita, H; Higuchi, T; Imamura, Y; Koga, T; Nozawa, M; Otagiri, M; Ryu, A1
Berges, R; Chaumontet, C; Heberden, C; Honikman-Leban, E; Krutovskikh, VA; Le Bon, AM; Martel, P; Shahin, MM; Suschetet, M; Yamasaki, H1
Canivenc-Lavier, MC; Le Bon, AM; Siess, MH; Suschetet, M1
Chatterjee, S; Nöldner, M1
Czeczot, H; Rahden-Staron, I; Szumilo, M1
Barotto, NN; Bongiovanni, GA; Díaz, MP; Eynard, AR; Valentich, MA1
Cai, HB; Collins, X; Edeki, TI; He, N; Strom, SC; Xie, HG1
Hayashi, SM; Imaoka, M; Ishii, Y; Kuwata, K; Mitsumori, K; Morita, R; Ogawa, B; Shibutani, M; Shimamoto, K; Suzuki, K1
Li, H; Lu, C; Shen, GL; Tan, Y; Xiao, WB; Zhuang, XM1

Reviews

1 review(s) available for phenobarbital and quercetin

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

19 other study(ies) available for phenobarbital and quercetin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Heterogeneity of carbonyl reduction in subcellular fractions and different organs in rodents.
    Biochemical pharmacology, 1991, Dec-11, Volume: 42 Suppl

    Topics: Adrenal Glands; Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Animals; Guinea Pigs; Kidney; Liver; Metyrapone; Phenobarbital; Quercetin; Rats; Rats, Inbred Strains; Subcellular Fractions

1991
Inhibition kinetics of human kidney aldose and aldehyde reductases by aldose reductase inhibitors.
    Biochemical pharmacology, 1990, Mar-15, Volume: 39, Issue:6

    Topics: Aldehyde Reductase; Aldehydes; Carbohydrate Dehydrogenases; Chromones; Humans; Imidazoles; Imidazolidines; Isoquinolines; Kidney; Kinetics; Naphthalenes; Phenobarbital; Phthalazines; Quercetin; Quinolones; Substrate Specificity; Sugar Alcohol Dehydrogenases

1990
Possible involvement of arachidonic acid metabolism in phenobarbital promotion of hepatocarcinogenesis.
    Carcinogenesis, 1989, Volume: 10, Issue:10

    Topics: Acetophenones; Animals; Arachidonic Acid; Arachidonic Acids; Biomarkers, Tumor; Body Weight; Diethylnitrosamine; Ethoxyquin; Flavonoids; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Phenobarbital; Quercetin; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate

1989
The mutagenic potencies of plant extracts containing quercetin in Salmonella typhimurium TA98 and TA100.
    Mutation research, 1988, Volume: 206, Issue:2

    Topics: Animals; Biotransformation; Flavonoids; Microsomes, Liver; Mutagenicity Tests; Mutagens; Phenobarbital; Plant Extracts; Quercetin; Rats; Salmonella typhimurium

1988
Absence of initiating activity by quercetin in the rat liver.
    Ecotoxicology and environmental safety, 1985, Volume: 10, Issue:1

    Topics: Animals; Carcinogens; Cells, Cultured; DNA Repair; Flavonoids; Hepatectomy; Liver; Male; Neoplasms, Experimental; Phenobarbital; Quercetin; Rats; Time Factors

1985
Inhibitory effects of inhibitors of arachidonic acid metabolism on the evolution of rat liver preneoplastic foci into nodules and hepatocellular carcinomas with or without phenobarbital exposure.
    Japanese journal of cancer research : Gann, 1993, Volume: 84, Issue:2

    Topics: Acetophenones; Animals; Arachidonic Acid; Aspirin; Cyclooxygenase Inhibitors; Diethylnitrosamine; Lipoxygenase Inhibitors; Liver Neoplasms, Experimental; Male; Phenobarbital; Phospholipases A; Phospholipases A2; Precancerous Conditions; Quercetin; Rats; Rats, Inbred F344

1993
Purification and catalytic properties of a novel acetohexamide-reducing enzyme from rabbit heart.
    Journal of biochemistry, 1996, Volume: 119, Issue:4

    Topics: Acetohexamide; Alcohol Oxidoreductases; Animals; Catalysis; Enzyme Inhibitors; Male; Molecular Weight; Myocardium; Phenobarbital; Quercetin; Rabbits; Substrate Specificity

1996
Lack of tumor-promoting effects of flavonoids: studies on rat liver preneoplastic foci and on in vivo and in vitro gap junctional intercellular communication.
    Nutrition and cancer, 1996, Volume: 26, Issue:3

    Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Carcinogens; Cell Line; Cricetinae; Flavanones; Flavones; Flavonoids; Gap Junctions; Glutathione Transferase; Hepatectomy; Liver Neoplasms; Male; Phenobarbital; Precancerous Conditions; Quercetin; Rats; Rats, Wistar

1996
Mechanisms involved in the chemoprevention of flavonoids.
    BioFactors (Oxford, England), 2000, Volume: 12, Issue:1-4

    Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Carcinogens; Chemoprevention; Cytosol; Diet; DNA; Flavanones; Flavones; Flavonoids; Glutathione; Liver; Liver Neoplasms, Experimental; Male; Phenobarbital; Quercetin; Rats; Rats, Wistar

2000
Effects of two different extracts of St. John's wort and some of their constituents on cytochrome P450 activities in rat liver microsomes.
    Pharmacopsychiatry, 2001, Volume: 34 Suppl 1

    Topics: Animals; Anthracenes; Antidepressive Agents; Bridged Bicyclo Compounds; Cytochrome P-450 Enzyme System; Ethanol; Excitatory Amino Acid Antagonists; Female; Hypericum; Liver; Male; Methanol; Microsomes; Perylene; Phenobarbital; Phloroglucinol; Plant Extracts; Quercetin; Rats; Rats, Sprague-Dawley; Sex Factors; Solvents; Terpenes

2001
Induction of rat liver cytochrome P450 isoenzymes CYP 1A and CYP 2B by different fungicides, nitrofurans, and quercetin.
    Mutation research, 2001, Nov-15, Volume: 498, Issue:1-2

    Topics: Animals; Carcinogens; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Ethidium; Fungicides, Industrial; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Mutagenicity Tests; Nitrofurans; Phenobarbital; Quercetin; Rats; Rats, Wistar

2001
Effect of the co-administration of phenobarbital, quercetin and mancozeb on nitrosomethylurea-induced pancreatic tumors in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2006, Volume: 44, Issue:12

    Topics: Alkylating Agents; Animals; Animals, Newborn; Carcinogens; Carcinoma in Situ; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Female; Fungicides, Industrial; Hyperplasia; Maneb; Maternal Exposure; Maternal-Fetal Exchange; Methylnitrosourea; Pancreatic Neoplasms; Phenobarbital; Pregnancy; Quercetin; Rats; Rats, Wistar; Zineb

2006
Induction of cyp3a in primary cultures of human hepatocytes by ginkgolides a and B.
    Clinical and experimental pharmacology & physiology, 2007, Volume: 34, Issue:7

    Topics: Adult; Aged; Blotting, Western; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Enzyme Induction; Female; Ginkgolides; Hepatocytes; Herb-Drug Interactions; Humans; Hydroxylation; Lactones; Male; Middle Aged; Phenobarbital; Quercetin; Rifampin; Testosterone

2007
Suppressive effect of enzymatically modified isoquercitrin on phenobarbital-induced liver tumor promotion in rats.
    Archives of toxicology, 2011, Volume: 85, Issue:11

    Topics: Animals; Anticarcinogenic Agents; Aryl Hydrocarbon Hydroxylases; ATP-Binding Cassette Transporters; Constitutive Androstane Receptor; Diethylnitrosamine; Drinking Water; Glutathione Transferase; Hepatectomy; Liver; Liver Neoplasms, Experimental; Male; Oxidative Stress; Phenobarbital; Quercetin; Rats; Rats, Inbred F344; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Steroid Hydroxylases

2011
Assessment of the roles of P-glycoprotein and cytochrome P450 in triptolide-induced liver toxicity in sandwich-cultured rat hepatocyte model.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:12

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; bcl-2-Associated X Protein; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diterpenes; Epoxy Compounds; Hepatocytes; Hydrogen Peroxide; Liver; Male; Phenanthrenes; Phenobarbital; Proto-Oncogene Proteins c-bcl-2; Quercetin; Quinolines; Rats; Rats, Sprague-Dawley; Ritonavir

2013