phenobarbital and procainamide

phenobarbital has been researched along with procainamide in 33 studies

Research

Studies (33)

Timeframe	Studies, this research(%)	All Research%
pre-1990	18 (54.55)	18.7374
1990's	1 (3.03)	18.2507
2000's	7 (21.21)	29.6817
2010's	7 (21.21)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Topliss, JG; Yoshida, F	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Sen, S; Sinha, N	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Harner, RS; McDowell, AE; Pardue, HL	1
Freeman, RW; Harbison, RD; Oates, JA; Woosley, RL	1
Eaton, DL; Klaassen, CD	1
Briggs, WA; Gibson, TP; Matusik, E; Nelson, LD	1
Reidenberg, MM	1
Pitterle, ME; Sorkness, CA; Wiederholt, JB	1
Homola, D; Rotrekl, J; Srnová, V	1
Enna, SJ; Schanker, LS	1
Kobayashi, K	1
Klaassen, CD	1
Emig, W	1
Grosser, KD; Humpert, U	1
Akera, T; Brody, TM; Kondo, H; Temma, K	1
Brouland, JP; Descotes, J; Patriarca, C; Verdier, F	1
SCHMIDT-VOIGT, J	1
KIMURA, E	1
MACKENZIE, GJ; PASCUAL, S	1
FOERSTER, K; KROETZ, C	1

Reviews

2 review(s) available for phenobarbital and procainamide

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug metabolism in uremia. Clinical nephrology, 1975, Volume: 4, Issue:3 Topics: Acetohexamide; Animals; Antipyrine; Humans; Hydrolysis; Lipid Metabolism; Microsomes, Liver; Oxidation-Reduction; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Procainamide; Rats; Tolbutamide; Uremia; Vitamin D	1975

Trials

1 trial(s) available for phenobarbital and procainamide

Article	Year
[Use of Coritrate in the prevention of paroxysmal tachycardia]. Vnitrni lekarstvi, 1973, Volume: 19, Issue:9 Topics: Adult; Aged; Ajmaline; Cardiac Glycosides; Clinical Trials as Topic; Drug Combinations; Female; Humans; Male; Meprobamate; Middle Aged; Phenobarbital; Procainamide; Quinidine; Tachycardia, Paroxysmal; Theophylline	1973

Other Studies

30 other study(ies) available for phenobarbital and procainamide

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Application of a vidicon spectrometer for simultaneous multicomponent drug determinations. Clinical chemistry, 1976, Volume: 22, Issue:11 Topics: Acetaminophen; Aminophylline; Barbiturates; Computers; Humans; Pharmaceutical Preparations; Phenobarbital; Phenylbutazone; Phenytoin; Procainamide; Regression Analysis; Salicylamides; Secobarbital; Spectrophotometry, Ultraviolet; Time Factors	1976
Evidence for the biotransformation of procainamide to a reactive metabolite. Toxicology and applied pharmacology, 1979, Volume: 50, Issue:1 Topics: Acetylation; Animals; Biotransformation; Hydralazine; Male; Mice; Microsomes, Liver; NADP; Phenobarbital; Proadifen; Procainamide; Salmonella typhimurium	1979
Effects of microsomal enzyme inducers on carrier-mediated transport systems in isolated rat hepatocytes. The Journal of pharmacology and experimental therapeutics, 1979, Volume: 208, Issue:3 Topics: Animals; Biological Transport, Active; Enzyme Induction; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Microsomes, Liver; Ouabain; Phenobarbital; Pregnenolone Carbonitrile; Procainamide; Rats; Taurocholic Acid	1979
Artificial kidneys and clearance calculations. Clinical pharmacology and therapeutics, 1976, Volume: 20, Issue:6 Topics: Blood Flow Velocity; Humans; Kidneys, Artificial; Mathematics; Metabolic Clearance Rate; Pharmaceutical Preparations; Phenobarbital; Plasma; Procainamide; Quinidine; Renal Dialysis; Urea	1976
Use of serum drug concentrations in outpatient clinics. American journal of hospital pharmacy, 1985, Volume: 42, Issue:7 Topics: Carbamazepine; Digoxin; Humans; Medication Systems, Hospital; Outpatient Clinics, Hospital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Procainamide; Quinidine; Theophylline; Wisconsin	1985
Absorption of drugs from the rat lung. The American journal of physiology, 1972, Volume: 223, Issue:5 Topics: Absorption; Aminohippuric Acids; Aniline Compounds; Animals; Antipyrine; Diffusion; Intestinal Absorption; Lung; Male; Pentobarbital; Permeability; Pharmaceutical Preparations; Phenobarbital; Procainamide; Pulmonary Alveoli; Rats; Salicylates; Sulfonic Acids; Tetraethylammonium Compounds	1972
[Experimental studies on the mechanism of digitalis and several antiarrhythmic agents--a consideration on roles of the central nervous system]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1972, Volume: 61, Issue:2 Topics: Ajmaline; Animals; Anti-Arrhythmia Agents; Brain; Cerebral Cortex; Digitalis Glycosides; Electrocardiography; Electroencephalography; Hypothalamus; Mesencephalon; Phenobarbital; Phenytoin; Procainamide; Propranolol; Rabbits; Thalamus	1972
Effects of phenobarbital on the plasma disappearance and biliary excretion of drugs in rats. The Journal of pharmacology and experimental therapeutics, 1970, Volume: 175, Issue:2 Topics: Animals; Bile; Bile Acids and Salts; Bilirubin; Chlorothiazide; Coloring Agents; Indocyanine Green; Male; Ouabain; Phenobarbital; Phenols; Probenecid; Procainamide; Rats; Succinates; Sulfathiazoles; Sulfobromophthalein	1970
[On the drug therapy of arrhytmias]. Die Medizinische Welt, 1966, Nov-19, Volume: 47 Topics: Arrhythmias, Cardiac; Humans; Meprobamate; Phenobarbital; Phytotherapy; Plants, Medicinal; Procainamide; Rauwolfia; Theophylline	1966
[On the therapy of the combination form of Adams-Stokes syndrome with orciprenaline]. Zeitschrift fur Kreislaufforschung, 1966, Volume: 55, Issue:10 Topics: Adams-Stokes Syndrome; Aged; Bronchodilator Agents; Electric Countershock; Female; Humans; Meperidine; Metaproterenol; Phenethylamines; Phenobarbital; Phytotherapy; Plants, Medicinal; Procainamide; Quinidine; Rauwolfia; Resorcinols; Ventricular Fibrillation	1966
Positive inotropic action of p-chloromercuribenzoate in isolated guinea-pig heart: influence of membrane stabilizing agents. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:3 Topics: Animals; Cell Membrane; Chloromercuribenzoates; Diphenhydramine; Drug Interactions; Ethylmaleimide; Female; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Ouabain; p-Chloromercuribenzoic Acid; Phenobarbital; Procainamide; Propranolol; Stereoisomerism	1981
Popliteal lymph node response to procainamide and isoniazid. Role of beta-naphthoflavone, phenobarbitone and S9-mix pretreatment. Toxicology letters, 1993, Volume: 66, Issue:1 Topics: Animals; Autoimmune Diseases; Benzoflavones; beta-Naphthoflavone; Biotransformation; Drug Evaluation, Preclinical; Enzyme Induction; Female; Isoniazid; Knee; Liver Extracts; Lymph Nodes; Male; Models, Biological; Phenobarbital; Procainamide; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Time Factors	1993
[Extrasystolic heart rhythm disorders; practical viewpoints on diagnosis and therapy]. Medizinische Klinik, 1958, Aug-01, Volume: 53, Issue:31 Topics: Arrhythmias, Cardiac; Humans; Phenobarbital; Plant Extracts; Procainamide; Quinidine; Vestibule, Labyrinth	1958
[ARRHYTHMIA]. Naika. Internal medicine, 1963, Volume: 12 Topics: Adrenal Cortex Hormones; Arrhythmias, Cardiac; Atropine; Diagnosis, Differential; Ephedrine; Epinephrine; Heart Block; Humans; Isoproterenol; Phenobarbital; Procainamide; Quinidine; Reserpine; Tachycardia	1963
PAROXYSMAL VENTRICULAR TACHYCARDIA. British heart journal, 1964, Volume: 26 Topics: Coronary Disease; Diagnosis; Digitalis Glycosides; Electrocardiography; Heart Failure; Hydrocortisone; Morphine; Mortality; Myocardial Infarction; Phenobarbital; Procainamide; Quinidine; Rheumatic Heart Disease; Statistics as Topic; Tachycardia; Tachycardia, Paroxysmal; Tachycardia, Ventricular; Toxicology	1964
[ANTI-ARRHYTHMIC SUBSTANCES IN THE TREATMENT OF THE HEART]. Medizinische Klinik, 1965, Apr-09, Volume: 60 Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Cardiac Complexes, Premature; Drug Therapy; Heart; Humans; Meprobamate; Phenobarbital; Procainamide; Quinidine; Rauwolfia; Tachycardia; Tachycardia, Paroxysmal; Theophylline; Ventricular Fibrillation	1965