phenobarbital has been researched along with probenecid in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (59.38) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (25.00) | 29.6817 |
| 2010's | 5 (15.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strassburg, CP; Tukey, RH | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bonow, A; Bräunlich, H; Schröter, S | 1 |
| Clifton, G; Kaplowitz, N; Wallin, JD | 1 |
| Bowers, MB; Cohen, DJ; Shaywitz, BA | 1 |
| Kaplowitz, N; Ryals, P; Wallin, JD | 1 |
| Bräunlich, H; Storch, R | 2 |
| Chen, CP; Wagner, C | 1 |
| Barzaghi, D; Salvaterra, M; Setnikar, I; Veronese, M | 1 |
| Ignarro, LJ; Wood, KS | 1 |
| Cucinell, SA; Dayton, PG; Perel, JM; Weiss, M | 1 |
| Klaassen, CD | 2 |
| Adamson, RH; Guarino, AM; Hart, LG | 1 |
| Sharpless, NS | 1 |
| Baumann, PA; De Herdt, P; Fehr, B; Maitre, L; Waldmeier, PC | 1 |
| Lyness, WH; Mycek, MJ | 1 |
| BURNS, JJ | 1 |
| GRACE, WJ; INGLESBY, TV; RIZZUTO, VJ | 1 |
| BURNS, JJ; CONNEY, AH; CUCINELL, SA; KOSTER, R | 1 |
| Ingham, AB; Kotze, AC; Ruffell, AP | 1 |
3 review(s) available for phenobarbital and probenecid
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
IMPLICATIONS ON ENZYME INDUCTION FOR DRUG THERAPY.
Topics: Animals; Benzopyrenes; Cyclizine; Dicumarol; Diphenhydramine; Dogs; Drug Therapy; Enzyme Induction; Enzymes; Glutethimide; Hexobarbital; Liver; Meprobamate; Metabolism; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Probenecid; Rats; Research; Tolbutamide; Toxicology; Zoxazolamine | 1964 |
29 other study(ies) available for phenobarbital and probenecid
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Age-dependence of renal tubular reabsorption of nitrofurantoin.
Topics: Absorption; Aging; Animals; Diuresis; Female; Hydrogen-Ion Concentration; Kidney Tubules; Nitrofurantoin; Phenobarbital; Probenecid; Rats | 1978 |
The effect of phenobarbital, probenecid and diethyl maleate on the pharmaco-kinetics and biliary excretion of ethacrynic acid in the rat.
Topics: Animals; Bile; Cytosol; Ethacrynic Acid; Glutathione Transferase; Kidney; Kinetics; Liver; Male; Maleates; Metabolic Clearance Rate; Phenobarbital; Probenecid; Protein Binding; Rats | 1978 |
Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy.
Topics: Acetazolamide; Adolescent; Age Factors; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Male; Phenobarbital; Phenylacetates; Phenytoin; Primidone; Probenecid | 1975 |
Metabolic clearance of furosemide in the rat.
Topics: Animals; Bile; Chromatography, Thin Layer; Furosemide; Metabolic Clearance Rate; Nephrectomy; Phenobarbital; Probenecid; Rats; Time Factors | 1977 |
[Concentration of p-aminohippuric acid in the serum and kidney tissue during stimulation of renal excretion of foreign materials].
Topics: Aminohippuric Acids; Animals; Cyclopenthiazide; Half-Life; Kidney; p-Aminohippuric Acid; Phenobarbital; Probenecid; Rats | 1977 |
[Extent and duration of drug-induced stimulation of renal excretion of p-aminohippuric acid].
Topics: Aminohippuric Acids; Animals; Cyclopenthiazide; Female; Glomerular Filtration Rate; Kidney; p-Aminohippuric Acid; Phenobarbital; Premedication; Probenecid; Rats; Stimulation, Chemical; Time Factors | 1976 |
Folate transport in the choroid plexus.
Topics: Animals; Biological Transport; Choroid Plexus; Dinitrophenols; Folic Acid; In Vitro Techniques; Kinetics; Oxygen; Phenobarbital; Phenytoin; Probenecid; Sodium; Swine; Tetrahydrofolates | 1975 |
Effects of different drugs on the urinary excretion of nifurpipone (NP) and of nitrofurantoin (NTF) in the rat.
Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Drug Interactions; Hydrochlorothiazide; Male; Nitrofurans; Nitrofurantoin; Phenobarbital; Proadifen; Probenecid; Quinine; Rats; Time Factors | 1975 |
Hepatic cyclic GMP formation is regulated by similar factors that modulate activation of purified hepatic soluble guanylate cyclase.
Topics: 1-Methyl-3-isobutylxanthine; Acetaminophen; Acetylcysteine; Animals; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Heme; Liver; Methylnitronitrosoguanidine; Mice; Nitroglycerin; Penicillamine; Phenobarbital; Phenylhydrazines; Potassium Cyanide; Probenecid; Protoporphyrins; Purinones; S-Nitroso-N-Acetylpenicillamine | 1987 |
Dose-dependence of drug plasma level decline in dogs.
Topics: Acetates; Animals; Barbiturates; Blood Proteins; Chlorine; Chromatography, Thin Layer; Dicumarol; Dogs; Kinetics; Liver; Muscles; Phenobarbital; Phenylbutazone; Phenytoin; Proadifen; Probenecid; Receptors, Drug; Vitamin K | 1967 |
Biliary excretion of barbiturates.
Topics: Animals; Barbiturates; Bile; Carbon Isotopes; Liver; Male; Pentobarbital; Phenobarbital; Probenecid; Rats; Time Factors | 1971 |
Effects of phenobarbital on the plasma disappearance and biliary excretion of drugs in rats.
Topics: Animals; Bile; Bile Acids and Salts; Bilirubin; Chlorothiazide; Coloring Agents; Indocyanine Green; Male; Ouabain; Phenobarbital; Phenols; Probenecid; Procainamide; Rats; Succinates; Sulfathiazoles; Sulfobromophthalein | 1970 |
Effects of phenobarbital on biliary excretion of organic acids in male and female rats.
Topics: Animals; Bile; Biliary Tract; Chlorothiazide; Female; Glucuronates; Indocyanine Green; Male; Phenobarbital; Phenolphthaleins; Probenecid; Rats; Sex Factors | 1969 |
Accelerated metabolism of probenecid during long-term treatment of rats with anticonvulsant drugs: effect on central serotonin turnover studies.
Topics: Animals; Anticonvulsants; Brain; Hydroxyindoleacetic Acid; Male; Phenobarbital; Phenytoin; Probenecid; Rats; Serotonin; Time Factors | 1981 |
Carbamazepine decreases catecholamine turnover in the rat brain.
Topics: alpha-Methyltyrosine; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain; Carbamazepine; Catecholamines; Dopamine; Dopamine beta-Hydroxylase; Female; Methoxyhydroxyphenylglycol; Methyltyrosines; Myocardium; Norepinephrine; Phenobarbital; Phenytoin; Probenecid; Rats; Rats, Inbred Strains | 1984 |
Potentiation of barbiturate hypnosis by probenecid: differential effect in tolerant animals.
Topics: Animals; Barbiturates; Brain; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Hexobarbital; Injections, Intraventricular; Liver; Male; Motor Activity; Phenobarbital; Probenecid; Rats; Reflex | 1981 |
PROBENECID (BENEMID) INTOXICATION WITH STATUS EPILEPTICUS.
Topics: Coma; Drug Therapy; Epilepsy; Gout; Phenobarbital; Phenytoin; Poisoning; Probenecid; Status Epilepticus; Suicide; Toxicology | 1965 |
APPLICATION OF DRUG METABOLISM TO DRUG TOXICITY STUDIES.
Topics: Aspirin; Blood; Chromatography; Dicumarol; Diphenhydramine; Dogs; Drug-Related Side Effects and Adverse Reactions; Glutethimide; Griseofulvin; Histamine H1 Antagonists; Liver; Meprobamate; Metabolism; Methylcholanthrene; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Piperazines; Probenecid; Rats; Research; Strychnine; Thiopental; Toxicology; Zoxazolamine | 1965 |
Phenobarbital induction and chemical synergism demonstrate the role of UDP-glucuronosyltransferases in detoxification of naphthalophos by Haemonchus contortus larvae.
Topics: Animals; Anthelmintics; Drug Resistance; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation; Glucuronosyltransferase; Haemonchus; Helminth Proteins; Inactivation, Metabolic; Larva; Organophosphorus Compounds; Phenobarbital; Probenecid; Sulfinpyrazone; Uracil | 2014 |