phenobarbital has been researched along with primidone in 669 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 588 (87.89) | 18.7374 |
| 1990's | 45 (6.73) | 18.2507 |
| 2000's | 23 (3.44) | 29.6817 |
| 2010's | 12 (1.79) | 24.3611 |
| 2020's | 1 (0.15) | 2.80 |
| Authors | Studies |
|---|---|
| Campbell, JA; Greenwood, TD; Rathman, TL; Sleevi, MC; Wolfe, JF | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Eadie, MJ; Lander, CM; Tyrer, JH | 1 |
| Roger, J; Tassinari, CA | 1 |
| Fayle, SA; Leppik, IE; McAuliffe, JJ; Pippenger, CE; Sherwin, AL | 1 |
| Richens, A | 2 |
| Kabra, PM; Marton, LJ; Stafford, BE | 1 |
| Callaghan, N; Duggan, PF; Feely, M; O'Callaghan, M | 1 |
| Driessen, OM; Goedhart, DM; Meijer, JW | 1 |
| Buchthal, A | 1 |
| Brechbühler, T; Schweizer, K; Wick, H | 1 |
| Egli, M | 1 |
| Dreifuss, FE | 2 |
| Mohrbacher, RJ; Riendeau, CJ; Werner, M | 1 |
| Chadwick, D; Jenner, P; Reynolds, EH | 1 |
| Cameron, JD; Hedley, DW | 1 |
| Ludwig, BI; Marsan, CA | 1 |
| Kutt, H | 4 |
| Hanson, JW; Smith, DW | 1 |
| Schmidt, D | 6 |
| Chadwick, D; Galbraith, AW; Reynolds, EH | 1 |
| Hopkins, A; Scambler, G | 1 |
| Johnson, RH; Lambie, DG; Nanda, RN; Shakir, RA | 1 |
| Fletcher, CD; McColl, KE; Thomson, TJ | 1 |
| Abarbanel, J; Eylath, U; Herishanu, Y; Rosenberg, P | 1 |
| Howland, C; McLean, AE; White, SJ | 1 |
| Bernhardt, W; Guthoff, A; Heipertz, R | 1 |
| Gromov, SA | 1 |
| Penin, H | 1 |
| Deisenhammer, E; Sommer, R | 2 |
| Rambeck, B | 1 |
| Aucamp, AK | 1 |
| Bardini, MR; Borgheresi, S; Buti Cossi, D; Luti, E; Mecherini, L | 1 |
| French, JH; McGregor, PA; Pippenger, CE; Rowan, AJ | 1 |
| Lison, MP; Speciali, GG | 1 |
| Livingston, S; Pauli, LL; Pruce, I | 2 |
| Albani, M; Gauchel, FD; Toseland, PA | 1 |
| Plaa, GL | 1 |
| Horton, RW; Meldrum, BS; Toseland, PA | 1 |
| Ahmad, S; Houghton, GW; Laidlaw, J; Richens, A | 1 |
| Müller-Oerlinghausen, B | 1 |
| Stores, G | 1 |
| McClean, SW; Rodbard, D | 1 |
| McClean, SW; Yonekawa, W; Young, DS | 1 |
| Brown, L; Horning, MG; Kellaway, P; Lertratanangkoon, K; Nowlin, J; Zion, TE | 1 |
| Adams, RF | 1 |
| Sauer, W; Windorfer, A | 1 |
| Hammond, KB | 1 |
| Stünkel, S; Weinmann, HM; Windorfer, A | 2 |
| Gascon Barré, M | 1 |
| Turri, JJ | 1 |
| Haeckel, R; Heyer, R; Külpmann, WR; Oellerich, M | 1 |
| Klotz, U | 1 |
| Conomy, JP | 1 |
| Miyamura, S; Yamada, M | 1 |
| Abilev, SK; Akin'shina, LP; Fonshtein, LM | 1 |
| Göbel, W; Löscher, W | 1 |
| Bruni, J | 3 |
| Campbell, DJ; Godolphin, W; Urquhart, N | 1 |
| Newmark, ME; Penry, JK | 1 |
| Hebdige, S; Oxley, J; Richens, A | 1 |
| Reith, H; Schäfer, H | 1 |
| Crawford, RD; Davis, HL; Johnson, DD | 2 |
| Berchou, RC; Lodi, RA; Sherman, JA | 1 |
| Fretthold, DW; Kumar, S; Pesh-Imam, M; Sunshine, I; Terrentine, S; Willis, CE | 1 |
| Hosokawa, K; Kugoh, T; Otsuki, S | 1 |
| Fichsel, H; Knöpfle, G | 1 |
| Livingston, S | 2 |
| Friis, ML | 1 |
| Stünkel, S; Windorfer, A | 1 |
| Freeman, DJ; Rawal, N | 1 |
| Shapiro, IuL; Vaĭntrub, MIa | 1 |
| Dymling, JF; Lidgren, L; Wallöe, A | 1 |
| Burk, PG; Nathanson, G; Pollack, MA | 1 |
| Krause, KH; Mehregan, U; Prager, P | 1 |
| Anglim, MA; Dolar, E; Least, CJ; St Onge, LM | 1 |
| Fröscher, W | 1 |
| Friel, PN; Leal, KW; Rapport, RL; Wilensky, AJ | 1 |
| Bérubé, L; Botez, MI; Labrecque, R; Peyronnard, JM | 1 |
| Rylance, GW | 1 |
| Frey, HH; Göbel, W; Löscher, W | 1 |
| Blaschke, E; Iffland, E; Lagenstein, I; Sternowsky, HJ | 1 |
| Abraham, CV; Gresham, D | 1 |
| Varma, R | 2 |
| Kaneko, S | 2 |
| Castro, A; Jatlow, PI; Malkus, H | 1 |
| Plenge, KL | 1 |
| Hadden, DR; Maclay, E; McIlrath, EM; Nesbitt, GS | 1 |
| Rosenmund, H; Wad, N | 1 |
| Burke, DG; Halpern, B; Korth, J; Summons, R; Truscott, RJ | 1 |
| Hewitt, TE; Kessler, G; Sievers, DL | 1 |
| Guelen, P; Knop, H; Schobten, F; van der Kleijn, E; Vree, T; Westenberg, H | 1 |
| Flanagan, RJ; Rutherford, DM | 1 |
| Christiansen, J; Friis, ML; Hvidberg, EF | 1 |
| Blake, DA; Freeman, JM; Luff, RD; Niebyl, JR | 1 |
| Perucca, E; Richens, A | 1 |
| Müller-Oerlinghausen, B; Riedel, E | 1 |
| Brachet, A; Henry, P; Loiseau, P | 1 |
| Dam, M; Hvidberg, EF | 1 |
| Bowers, MB; Cohen, DJ; Shaywitz, BA | 1 |
| Ferry, D; Ferry, DG; McQueen, EG | 1 |
| Freeman, JM; Singer, HS | 1 |
| Kupferberg, HJ; Sutton, G | 1 |
| Dekaban, AS; Lehman, EJ | 1 |
| Bolin, RH; Bruya, MA | 1 |
| Goodman, RM; Hertz, M; Katznelson, D; Katznelson, MB; Rotem, Y | 1 |
| Karbowski, K; Meienberg, O | 1 |
| Knotts, GR; Thomas, JA | 1 |
| Bruce, AM; Smith, H | 2 |
| Morgan, JP; Myers, GJ; Syversen, GB; Weintraub, M | 1 |
| Johnson, GF; Least, CJ; Solomon, HM | 1 |
| Anast, CS; Russell, B; Saunders, JA; Winnacker, JL; Yeager, H | 1 |
| Ayers, GJ; Burnett, D; Goudie, JH; Reed, K | 1 |
| Hill, RE; Latham, AN | 1 |
| Bill, P; Buchanan, N; Eyberg, C; Fernandes Costa, F; Moodley, GP; Strickwold, B | 1 |
| Ashworth, B; Horn, DB | 1 |
| Eickhoff, K; Heipertz, R; Pilz, H | 1 |
| Bius, DL; Boyles, LW; Dudley, KH; Kraus, BL | 1 |
| Bartels, H; Kruse, K; Oldigs, HD | 1 |
| McElhatton, PR; Sullivan, FM | 2 |
| Callaghan, N; Duggan, F; Feely, M; O'Callaghan, M; Seldrup, J | 1 |
| Habersang, R; Kauffman, RE; Lansky, L | 1 |
| Brachet-Liermain, A; Centraud, B; Loiseau, P | 1 |
| Cameron, JD; Chambers, RE | 1 |
| Tomasi, LG | 1 |
| Iwai, H; Kubo, S; Kuyama, C; Watanabe, S; Yokoyama, S | 1 |
| McElhatton, PR; Sullivan, FM; Toseland, PA | 2 |
| Eadie, MJ; Hooper, WD; Lander, CM; Tyrer, JH | 1 |
| Florey, JB; Goller, VL; Klein, GL; Larese, RJ; Van Meter, QL | 1 |
| Abraham, CV | 1 |
| Adams, RF; Vandemark, FL | 2 |
| Johnson, GF; Least, CJ; Serum, JW; Solomon, HM; Solow, EB | 1 |
| Hansen, S; MacLean, J; Perry, TL | 1 |
| Ionasescu, V; Waziri, M; Zellweger, H | 1 |
| Andresen, BD; Davis, FT; Hammer, RH; Panzik, HL; Templeton, JL | 1 |
| Chadwick, D; Fairhurst, E; Reynolds, EH; Ridge, BD | 1 |
| Latham, AN; Varlow, G | 1 |
| Jeremić, V; Nikolić, R | 1 |
| Cramers, CA; Hulsman, JA; Meijers, CA; van Kuik, LG; Vermeer, EA | 1 |
| Kitamura, M; Nishina, T; Okoshi, K | 1 |
| Abraham, CV; Joslin, HD | 2 |
| Chadwick, D; Marsden, CD; Reynolds, EH | 1 |
| Bailey, DG; Davis, HL; Johnson, GE; Wilson, TW | 1 |
| Baumel, IP; Dimicco, JA; Gallagher, BB; Woodbury, SG | 1 |
| Coulthard, MG | 1 |
| Wallace, SJ | 1 |
| Ajmone-Marsan, C; Mutsuga, N; Sadowsky, D; Van Buren, JM | 1 |
| Friel, P; Troupin, AS | 2 |
| Gädeke, R; Sauer, M; Windorfer, A | 2 |
| Fenton, G; Fenwick, P; Johnson, AL; Laundy, M; Reynolds, EH | 1 |
| Baars, I; Guelen, PJ; Kleijn, E; Vree, TB | 1 |
| Bailey, DG; Davis, HL; Falk, KJ | 1 |
| Alvin, J; Bush, MT; Goh, E | 1 |
| Bosl, R; Buselmeier, TJ; Kjellstrand, CM; Meyer, RM; Shideman, JR; von Hartitzsch, B | 1 |
| Joern, WA | 1 |
| Alvin, JD; Bush, MT | 1 |
| Blaskovics, ME; Podosin, RL; Roe, TF | 1 |
| Harley, JP; Matthews, CG | 1 |
| Aderet, NB; Biale, Y; Lewenthal, H | 1 |
| DuCharme, LL; Farquhar, JA; Huntsman, BJ; Lockard, JS; Uhlir, V | 1 |
| Wehrhahn, L; Wiegrebe, W | 1 |
| Schlunegger, UP; Wehrhahn, L; Wiegrebe, W | 1 |
| Chadwick, D; Chanarin, I; Jenner, P; Reynolds, EH | 1 |
| Annegers, JF; Elveback, LR; Hauser, WA; Kurland, LT | 2 |
| Cate JC, IV; Tenser, R | 1 |
| Kupferberg, J; Schmidt, D | 1 |
| Davidson, S; Houghton, GW; Richens, A; Toseland, PA | 1 |
| Borst, SI; Lockwood, CH | 1 |
| Legaz, M; Raisys, VA | 1 |
| Buddington, R; Daly, DD; Penry, JK; Pippenger, CE; White, BG | 1 |
| Gotelli, G; Kabra, PM; Marton, LJ; Stanfill, R | 1 |
| Hill, JG; Soldin, SJ | 1 |
| Dorrity, F; Linnoila, M | 1 |
| Goto, T; Ito, K; Kobayashi, Y; Owada, E; Sakuta, N; Sato, J; Sekizawa, Y; Yoshida, A; Yoshihara, M | 1 |
| Watanabe, M; Yagi, K | 1 |
| Kaciński, M | 1 |
| Hooper, WD; Treston, AM | 2 |
| Benedetti, TJ; Erickson, DM; Leavitt, A; Loewenson, RB; McCormick, KB; Sells, CJ; Yerby, MS | 1 |
| Burlina, A; Mould, GP; Müller, C; Stamp, RJ | 1 |
| Jürgens, U; Schwartz-Porsche, D | 1 |
| Calzetti, S; Fava, R; Perucca, E; Sasso, E | 2 |
| Matisová, E; Pham Thi, Ha; Volmut, J | 1 |
| Haginaka, J; Kimura, Y; Wakai, J; Yasuda, H | 1 |
| Bausch, S; Blackwood, J; Gassmann, S; Grün, K; Inbar, S; Kreider, R; Löchel, B; Siebert, M; Walter, G | 1 |
| Calzetti, S; Gatti, G; Martines, C; Perucca, E; Sasso, E | 1 |
| Berry, DJ; Groggin, MJ; Jones, JA; Streete, JM | 1 |
| Aoyama, T; Higuchi, S; Yukawa, E | 1 |
| Armijo Simón, JA; Arteaga Manjón-Cabeza, R; Herranz Fernández, JL | 1 |
| Chung, MY; Lin, SL | 1 |
| Cramer, JA; Mattson, RH; McCutchen, CB | 1 |
| Hönack, D; Löscher, W | 1 |
| Knott, C; Reynolds, F | 3 |
| Kattah, JC; Kurtzke, JF; Lux, WE; Masucci, EF; Schwankhaus, JD | 1 |
| Higashi, A; Inotsume, N; Kinoshita, E; Matsuoka, T; Nakano, M | 1 |
| Findley, LJ | 2 |
| Braide, SA; Davies, TJ | 1 |
| Hartshorn, EA; Hartshorn, JC | 1 |
| Löscher, W; Schwartz-Porsche, D | 1 |
| Canevini, MP; Canger, R; Cornaggia, CM; Giuccioli, D; Pruneri, C | 1 |
| Frey, HH | 1 |
| Berry, DJ; Newbery, JE; Pettit, LI; Streete, JM | 1 |
| Baciewicz, AM | 1 |
| Shinnar, S | 1 |
| Bourgeois, BF | 1 |
| Coulter, DL | 1 |
| Hobusch, D; Popp, K; Rohmann, E; Schwebke, D; Sengbusch, S | 1 |
| Collins, JF; Cramer, JA; Mattson, RH | 1 |
| Carl, GF; Smith, ML | 1 |
| Kaciński, M; Stopyrowa, J; Szafran, Z; Sztefko, K | 1 |
| Calzetti, S; Perucca, E; Sasso, E | 1 |
| Collins, JF; Craft, B; Cramer, JA; Mattson, RH; Novelly, RA; Smith, DB | 1 |
| Borromei, A; Caramelli, R; Cipriani, G; Giancola, LC; Guerra, L; Lozito, A | 1 |
| Holl, G; Honé, A; Seyfert, S | 1 |
| Honhold, N; Morton, DJ | 1 |
| Helge, H; Koch, S; Kuhnz, W; Nau, H | 1 |
| Porter, RJ; Raubertas, RF; Theodore, WH | 1 |
| Barthel, A; Obe, G; Riedel, L; Schwartz-Porsche, D | 1 |
| Brooks, RA; DiChiro, G; Fishbein, D; Margolin, R; Porter, RJ; Theodore, WH | 1 |
| Vining, EP | 1 |
| Spina, E; Tomson, T; Wedlund, JE | 1 |
| Rao, KP; Rao, MS; Shaheen, S; Usha Rani, MV | 1 |
| Baldwin, BH; Bunch, SE; Castleman, WL; Center, SA; Conway, MB; Hornbuckle, WE; Tennant, BC | 1 |
| Landon, J; Sidki, AM; Smith, DS | 1 |
| Caron, G; Sheehan, M | 1 |
| Levy, RH; Yerby, MS | 1 |
| Browne, TR; Collins, JF; Cramer, JA; Delgado-Escueta, AV; Mattson, RH; McCutchen, CB; McNamara, JO; Smith, DB; Treiman, DM; Williamson, PD | 1 |
| Ishizaki, T; Kushida, K | 1 |
| Canevini, MP; Canger, R; Cornaggia, C; Giuccioli, D; Pinelli, P; Pruneri, C | 1 |
| Frey, HH; Löscher, W | 2 |
| Koller, WC; Royse, VL | 1 |
| Richter, K; Schmidt, D | 1 |
| Bonin, P; Casara, GL; Furlanut, M; Montanari, G | 1 |
| Frey, HH; Löscher, W; Schwartz-Porsche, D | 1 |
| Deliconstantinos, G; Tsakiris, S | 1 |
| Baylis, EM; Crowley, JM; Marks, V; Preece, JM; Sylvester, PE | 1 |
| Lowe, CR | 1 |
| Reynolds, EH | 5 |
| Davidson, S; Falconer, MA | 1 |
| Clemmesen, J; Fuglsang-Frederiksen, V; Plum, CM | 1 |
| Kutt, H; Penry, JK | 1 |
| Bochentin, W; Koeppe, P; Kraft, D; Opitz, A; Schaefer, K; von Herrath, D | 1 |
| Kyogoku, Y; Yu, NT | 1 |
| Aarli, JA | 1 |
| Sibley, WA | 1 |
| McLellan, DL; Swash, M | 1 |
| Davies, TJ; Kupersmitt, E; Orme, M; Petrie, A; Silver, J; Vajda, F | 1 |
| Davidson, DC; Ford, JA; McIntosh, WB | 1 |
| Kar, PP; Matin, MA | 1 |
| Parsonage, M | 1 |
| Matthews, DM; Reynolds, EH | 1 |
| Chanarin, I; Matthews, DM; Reynolds, EH | 1 |
| Discombe, C; Evans, AR; Forrester, RM | 1 |
| Salomon, B; Schütze, I; Thal, W | 1 |
| Fehling, C; Jägerstad, M; Lindstrand, K; Westesson, AK | 1 |
| Meyer, JG | 2 |
| Brill, PW; Leonidas, JC; Waldman, N | 1 |
| Billinghurst, JR; German, GA; Orley, JH | 1 |
| Leary, PM | 1 |
| Brock, JT; Cereghino, JJ; Ellenberg, J; Fisher, P; Penry, JK; Smith, LD; Van Meter, JC | 1 |
| Gold, AP | 1 |
| Christiansen, C; Rodbro, P; Sjö, O | 1 |
| Bielmann, P; Langlois, Y; Levac, TH; Tetreault, L | 1 |
| Forman, PM | 1 |
| Taguchi, H | 1 |
| Canger, R | 1 |
| Millichap, JG | 2 |
| Delling, G; Lücking, T | 1 |
| Eisen, AA; Sherwin, AL; Woods, JF | 1 |
| Freeman, JM; Lietman, PS | 1 |
| Hooshmand, H | 1 |
| Liu, MC | 1 |
| Sayers, A; Stille, G | 1 |
| Bogan, J; Smith, H | 1 |
| Rümke, CL | 1 |
| Gibberd, FB | 1 |
| Wilson, J | 1 |
| Rowan, AJ; Scott, D | 1 |
| Saad, SF | 1 |
| Göres, E; Kurze, G; Oehme, P | 1 |
| Mandel, HG; Riis, M | 1 |
| Gardner-Thorpe, C; Parsonage, MJ; Toothill, C | 1 |
| Ente, G; Pochedly, C | 1 |
| Kutt, H; Louis, S | 1 |
| Spector, RG | 1 |
| Röttger, HJ; Windorfer, A | 1 |
| Ballinger, BR; Simpson, E; Stewart, MJ | 1 |
| Parker, WA | 1 |
| Livingston, S; Pauli, LL | 1 |
| Bowden, AN; Livingston, S; Pauli, LL | 1 |
| Fenton, GM; Laundy, M; Reynolds, EH; Slavin, BN | 1 |
| Bredesen, JE; Johannessen, SI | 1 |
| Beam, RE | 1 |
| Cavazzuti, GB | 2 |
| Windorfer, A | 1 |
| Hilgartner, MW; Kutt, H; Solomon, GE | 1 |
| Bock, GW; Loynd, JS; Sherwin, AL; Sokolowski, CD | 1 |
| Stüttgen, G | 1 |
| Garrettson, LK | 1 |
| Gallagher, BB; Glass, D; Mattson, RH; Reynolds, EH | 1 |
| Birket-Smith, E; Holm, P; Lund, M; Mikkelsen, B; Olsen, PZ; Vestermark, S | 1 |
| Gregoriades, AD | 1 |
| Gallagher, BB; Reynolds, EH; Travers, RD | 1 |
| Baumel, IP; Gallagher, BB; Mattson, RH | 2 |
| Dvilansky, A; Lehman, E | 1 |
| Horne, PD | 1 |
| Bailey, DN; Jatlow, PI | 1 |
| Flury, W | 1 |
| Foerst, D | 1 |
| Gallagher, BB; Mattson, RH; Reynolds, EH | 1 |
| Green, JB; Solow, EB | 1 |
| Burnett, D; Goudie, JH | 1 |
| Haerer, AF; Hull, RP | 1 |
| Rundle, AT; Sudell, B | 1 |
| Rodgers, G; Roger, JC; Soo, A | 1 |
| Perchalski, RJ; Wilder, BJ | 2 |
| Baumel, IP; DiMicco, J; Gallagher, BB; Goico, H | 1 |
| Wilkinson, GR; Wilson, JT | 2 |
| Slomic, A; Szöts, F | 1 |
| Lifshitz, F; Maclaren, NK | 1 |
| Latham, AN; Richens, A | 1 |
| Baumel, IP; Gallagher, BB; Mattson, RH; Woodbury, SG | 1 |
| Brock, JT; Cereghino, JJ; Meter, JC; Penry, JK; Smith, LD; White, BG | 1 |
| Martinez, G; Snyder, RD | 1 |
| Fincham, RW; Schottelius, DD | 1 |
| Henriksen, O; Loyning, Y | 1 |
| Hammer, RH; Perchalski, RJ; Scott, KN; Wilder, BJ | 1 |
| Cremers, HM; Verheesen, PE | 1 |
| Garceau, Y; Hasegawa, J; Philopoulos, Y | 1 |
| Couch, MW; Greer, M; Williams, CM | 1 |
| Christiansen, C; Lund, M; Rodbro, P | 1 |
| Skrotskiĭ, IuA | 1 |
| Heischkeil, R | 1 |
| Fincham, RW; Sahs, AL; Schottelius, DD | 2 |
| Baylis, EM; Fry, DE; Marks, V; Papadopoulos, AS | 1 |
| Medlinsky, HL | 1 |
| Brillman, J; Gallagher, BB; Mattson, RH | 1 |
| Hill, RM; Horning, MG; McCulley, LB; Morgan, NF; Verniaud, WM | 1 |
| Wilson, JT | 1 |
| Metaxas, JM; Solow, EB; Summers, TR | 1 |
| Arakawa, T; Karahashi, M; Takagi, T; Tanabu, M; Yoshida, T | 2 |
| Reynolds, EH; Travers, RD | 1 |
| Breckenridge, A; Davidson, S; Falconer, MA; Vajda, F; Williams, FM | 1 |
| Kurata, D; Wilkinson, GR | 1 |
| Jensen, ON; Olesen, OV | 2 |
| Ristić, J | 1 |
| Gudmundsson, G | 1 |
| Matthes, A | 1 |
| Dam, M; Olesen, OV | 1 |
| Roth, G | 1 |
| Borkowska, Z; Mazurkowa, K; Wojakowski, A | 1 |
| Cosyns, L; Dvornik, D; Kraml, M | 1 |
| el-Masry, AM; Saad, SF; Scott, PM | 1 |
| Haining, RG; Labbé, RF; Lefebvre, EB | 1 |
| Berry, DJ; Grove, J; Toseland, PA | 1 |
| De Luca, K; Masotti, RE; Partington, MW | 1 |
| Borgstedt, AD; Bryson, MF; Forbes, GB; Young, LW | 1 |
| Gardner-Thorpe, C; Parsonage, MJ; Smethurst, PF; Toothill, C | 1 |
| Majkowski, J | 2 |
| Schulze, B | 1 |
| Kupferberg, HJ | 2 |
| Harms, D | 1 |
| Dennis, NR | 1 |
| Dobrzyńska, L; Szelozyńska, K | 1 |
| Kolodziej, A; Radomska, M; Wierzbowska, A | 1 |
| Fuglsang-Fredriksen, V; Linde, J; Molholm Hansen, J; Siersbaek-Nielsen, K | 1 |
| Danielsson, B | 1 |
| Gallagher, BB; Glaser, GH; Travers, RD | 1 |
| Chanarin, I; Matthews, DM; Milner, G; Reynolds, EH | 1 |
| Huisman, JW; van Heycop ten Ham, MW; van Zijl, CH | 1 |
| Booker, HE; Burdette, RD; Darcey, B; Hosokowa, K | 1 |
| Golden, GS | 1 |
| Hommes, OR; Houben, PF; Knaven, PJ | 1 |
| Norton, J; Plott, D; White, PT | 1 |
| Viukari, NM | 1 |
| Juul, S | 1 |
| Matti, N; Tammisto, P; Viukari, A | 1 |
| Iaroslavskiĭ, AA; Shimanko, II | 1 |
| Tammisto, P; Viukari, NM | 1 |
| Buckmaster, HS; Shelley, LL; Van Meter, JC | 1 |
| Isumi, N | 1 |
| Richens, A; Rowe, DJ | 1 |
| Kocen, RS; Lascelles, PT; Reynolds, EH | 1 |
| Heyndrickx, A; Okkerse, E; Van Hoof, F | 1 |
| Fletcher, BD; Lussier-Lazaroff, J | 1 |
| Elshove, J; van Eck, JH | 1 |
| Harasymiv, I; Hensley, WJ; Sampson, D | 1 |
| Meinardi, H | 1 |
| Fujimoto, JM; Mason, WH; Murphy, M | 1 |
| McGregor, JG; Schreiber, MM | 1 |
| Gordon, N | 1 |
| Gillen, HW; Pippenger, CE; Scott, JE | 1 |
| Bittner-Manicka, M; Majkowski, J; Wasilewski, R | 1 |
| Peters, BH; Samaan, NA | 1 |
| Huisman, JW | 2 |
| Gillen, HW; Pippenger, CE | 1 |
| Dayton, PG; Garrettson, LK; Perel, JM | 1 |
| Collins, AJ; Horlington, M | 1 |
| Bush, MT; Helman, E | 1 |
| Dvornik, D; Kraml, M; Marton, AV | 1 |
| Dzialek, E; Góral, Z | 1 |
| Ahuja, GK; Schumacher, GA | 1 |
| Olesen, OV | 2 |
| Rousso, C | 1 |
| Tollefson, G | 1 |
| Maheshwari, MC | 1 |
| Alderdice, MT; Talbot, PA | 2 |
| Deisenhammer, E; Schwarzbach, H; Sommer, R | 1 |
| Breuer, H; Fleischhauer, K; Höller, M | 1 |
| Neuvonen, PJ; Tokola, RA | 1 |
| Hosokawa, K; Kugoh, T | 1 |
| Brune, GG; Nautsch, JP; Rolf, LH | 1 |
| Bourgeois, BF; Dodson, WE; Ferrendelli, JA | 3 |
| Crout, BO; Gross, JA; Swift, TR; Ward, LC | 1 |
| Reynolds, EH; Shorvon, SD | 2 |
| Dietzler, DN; Hoelting, CR; Leckie, MP; Porter, SE; Smith, CH; Tieber, VL | 1 |
| Cramer, JA; Delgado Escueta, AV; Mattson, RH; Smith, DB | 1 |
| Aicardi, J; Vajda, FJ | 1 |
| Haven, GT; Kiser, EJ; Studts, D | 1 |
| Ou, CN; Rognerud, CL | 1 |
| Rowan, AJ | 1 |
| Crema, A; Perucca, E | 1 |
| Armijo, JA; Arteaga, R; Herranz, JL | 1 |
| Callaghan, N; Keating, J; O'Dwyer, R | 1 |
| Albright, PS; Bruni, J | 1 |
| Helge, H; Jäger-Roman, E; Kuhnz, W; Nau, H; Rating, D | 1 |
| Hedges, A; Makki, KA; Perucca, E; Richens, A; Ruprah, M; Wilson, JF | 1 |
| Alonso, RJ; Covington, TR; Mancall, EL | 1 |
| De Paiva, VJ; Subirana, A; Subirana, M | 1 |
| Forsythe, WI; Sills, MA | 1 |
| Giese, RW; Jaramillo, L; Karger, BL; Nazareth, A; Snyder, LR | 1 |
| Painter, MJ; Pippenger, CE; Powell, C | 1 |
| Andriolo, A; Germek, OA; Pereira, AB | 1 |
| Berlit, P; Bonjour, JP; Kochen, W; Krause, KH | 1 |
| Farnbach, GC | 2 |
| D'Agostino, AA; Di Perri, R; Fazio, A; Oteri, G; Perucca, E; Petrelli, RM; Pisani, F; Primerano, G | 1 |
| Chan, K; Lok, S; Teoh, R | 1 |
| Obe, G; Riedel, L | 1 |
| Fröscher, W; Hoffmann, F | 1 |
| Bennett, HS; Dunlop, T; Ziring, P | 1 |
| de Jong, W; Seldenrijk, R; van Dijk, A; van Heijst, AN | 1 |
| Börner, W; Hoffmann, R; Moll, E; Reiners, C | 1 |
| Altamura, AC; Bianchi, M; Canger, R; Cornaggia, CM; Polana, P; Pruneri, C | 1 |
| Collins, JF; Cramer, JA; Delgado Escueta, AV; Mattson, RH; Smith, DB | 1 |
| Bell, F; Chan, S; Gerson, B | 1 |
| Frey, HH; Löscher, W; Reiche, R; Schultz, D | 1 |
| Höller, M; Penin, H | 1 |
| Deisenhammer, E; Nitsche, V; Sommer, R | 1 |
| Franco-Morselli, R; Morselli, PL | 1 |
| Kingsley, E; Tolman, KG; Tweedale, R | 1 |
| Quednow, B; Walther, H | 1 |
| O'Brien, MD; Toseland, PA; Upton, AR | 1 |
| Aminoff, MJ | 1 |
| Baruzzi, A; Lugarezi, E; Martinelli, P; Pazzaglia, P; Procaccianti, G | 1 |
| Scollo-Lavizzari, G | 1 |
| Karbowski, K | 1 |
| Minagawa, K; Miura, H | 1 |
| Cohan, SL | 1 |
| Koch, KM; Levy, RH | 1 |
| Richter, K; Scherber, A | 1 |
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| Kido, H | 1 |
| Kabra, PM; Marton, LJ; Nelson, MA | 1 |
| Bartels, H; Günther, E; Wallis, S | 1 |
| Chiba, K; Ishizaki, T; Kushida, K | 1 |
| Avanzini, G; Battino, D; Bossi, L; Croci, D; Cusi, C; Gomeni, C; Moise, A | 1 |
| Johnson, RH; Lambie, DG | 2 |
| Cunningham, JG; Haidukewych, D; Jensen, HA | 1 |
| Neels, HM; Scharpé, SL; Totté, JA; Verkerk, RM; Vlietinck, AJ | 1 |
| Browne, TR; Szabo, GK | 1 |
| Meijer, JW; Rambeck, B; Riedmann, M | 1 |
| Eadie, MJ; Heazlewood, R; Tyrer, JH | 1 |
| Bannister, SJ; Dolan, JW; Snyder, LR; van der Wal, S | 1 |
| Külpmann, WR | 1 |
| Dietzler, DN; Hoelting, CR; Leckie, MP; Smith, CH; Tieber, VL | 1 |
| Holliday, TA | 1 |
| Lacher, DA; Savory, J; Sinn, JA; Wills, MR | 1 |
| Knight, D | 1 |
| Igari, J; Kanazawa, T; Takahashi, K | 1 |
| Külpmann, WR; Oellerich, M | 1 |
| Kupferberg, HJ; Newmark, ME; Porro, MG; Porter, RJ; Theodore, WH | 1 |
| Bunch, SE; Castleman, WL; Hornbuckle, WE; Tennant, BC | 1 |
| Assael, BM; Avanzini, G; Battino, D; Bossi, L; Caccamo, ML; Canger, R; Como, ML; de Giambattista, M; Franceschetti, S; Marini, A; Pardi, G; Pifarotti, G; Porro, MG; Rovei, V; Sanjuan, M; Soffientini, ME; Spina, S; Spreafico, R | 1 |
| Jaffery, FN; Matin, MA; Siddiqui, RA | 1 |
| Aguilera, L; Galdames, D; Ortiz, M; Saavedra, I | 1 |
| Yeary, RA | 1 |
| Arranz Peña, MI | 1 |
| Mattson, RH; Spencer, DD; Spencer, SS; Williamson, PD | 1 |
| Davis, CM; Fenimore, DC | 1 |
| Brügmann, G | 1 |
| Ahlfors, UG; Ebeling, P; Helenius, T; Liewendahl, K; Majuri, H | 1 |
| Kapetanović, IM; Kupferberg, HJ | 1 |
| Oettinger, B; Richter, K | 1 |
| Maheshwari, MC; Padmini, R | 1 |
| Ahmad, SN; Jaffery, NF; Jailkhani, BL | 1 |
| Gross, AJ; Morton, WA; Saunders, S; Wannamaker, BB | 1 |
| Christofides, JA; Fry, DE | 1 |
| Cabrini, G; Marossero, F; Porro, MG; Ravagnati, L; Sironi, VA | 1 |
| Kumps, A; Mardens, Y | 1 |
| Jesdinsky, D; Nau, H; Wittfoht, W | 1 |
| Soldin, SJ | 1 |
| Häuser, I; Helge, H; Jäger, E; Koch, S; Nau, H; Rating, D | 1 |
| Bartels, H; Dreller, E; Kracht, U; Kruse, K | 1 |
| Arko, K; Barbarić, V; Hajnsek, F | 1 |
| Cloyd, JC; Leppik, IE; Miller, KW | 1 |
| Sterman, MB | 1 |
| Cloyd, J; Garnett, WR; Holmes, GL; Meyer, MC; Schiffer, JR | 1 |
| Branford, D; Collacott, RA | 1 |
| Furuno, K; Gomita, Y; Moriyama, M; Oishi, R | 1 |
| Metzer, WS | 1 |
| Hekster, YA; Keyser, A; Lammers, MW; Meinardi, H; Renier, WO; van Lier, H; Wijsman, DJ | 1 |
| Manaligod, JM; Marchlewski, A; Sylvester, CE | 1 |
| Schmutz, A; Thormann, W | 2 |
| Kucharczyk, N; Romanyshyn, LA; Shumaker, RC; Sofia, RD; Ward, D; Wichmann, JK | 1 |
| Delgado, M; Eggers, CM; Forman, LJ; Liu, H; Montoya, JL | 1 |
| Avanzini, G; Battino, D; Estienne, M | 1 |
| Marchand, L | 1 |
| Hasegawa, H; Kanner, AM | 1 |
| Ebner, A; Hermanns, G; Holthausen, H; Noachtar, S; Tuxhorn, I; Wolf, P | 1 |
| Helge, H; Jäger-Roman, E; Koch, S; Lösche, G; Nau, H; Rating, D | 1 |
| Perucca, E; Pisani, F; Spina, E | 1 |
| Ferrera, PC; Thibodeau, LG | 1 |
| Calvert, C; Jacobs, G; Kaufman, A | 1 |
| Luer, MS; Winkler, SR | 1 |
| Boothe, DM | 1 |
| Bates, D; Privitera, M; Warner, A | 1 |
| El-Masri, HA; Portier, CJ | 1 |
| Cassim, F; Destée, A; Guieu, JD; Mastain, B | 1 |
| Schlienger, RG; Shear, NH | 1 |
| Carrillo, J; Schwark, WS; Trepanier, LA; Van Schoick, A | 1 |
| Chabenat, C; Ferranti, V; Lafont, O; Ménager, S | 1 |
| Chadwick, D | 1 |
| Chen, C; Cox, E; Fiedler-Kelly, J; Grasela, TH; Risner, ME; Womble, GP | 1 |
| Apeland, T; Kristensen, O; Mansoor, MA; Strandjord, RE | 1 |
| Frey, M; Kanner, AM; Parra, J | 1 |
| Knudsen, FU | 1 |
| Chabenat, C; Ferranti, V; Hue, H; Lafont, O; Marchais, H; Ménager, S; Orecchioni, AM | 1 |
| Laskowska, M; Leszczyńska-Gorzelak, B; Oleszczuk, J | 1 |
| Carvalho, D; Lanças, FM; Queiroz, ME; Silva, SM | 1 |
| Alkhamis, KA; Wurster, DE | 1 |
| GOODMAN, LS; SWINYARD, EA; TEDESCHI, DH | 1 |
| BUTLER, TC; WADDELL, WJ | 1 |
| SOREL, L | 1 |
| BENIANS, RC; HUNTER, RA | 1 |
| GRANT, P; GRUBER, CM; MOSIER, JM | 1 |
| FUJIMOTO, JM; HINE, CH; PLAA, GL | 1 |
| FAZEKAS, IG; RENGEI, B | 1 |
| POECK, K | 1 |
| CHIESARA, E; KATO, R; VASSANELLI, P | 1 |
| BAILEY, AA | 1 |
| BOND, WH; CHILDRESS, RH; LONG, MT | 1 |
| HAUG, U; PANESCU, I | 1 |
| CHALMERS, JN; HORSFIELD, GI | 1 |
| BAKER, L; KAHN, SB; LISCHNER, H; WILLIAMS, WJ | 1 |
| HASSAN, AH | 1 |
| HENSON, RA | 1 |
| KLIPSTEIN, FA | 1 |
| HOLT, KS | 1 |
| HUTNER, SH | 1 |
| ARIMA, M; FUKUYAMA, Y; NAGAHATA, M; OKADA, R | 1 |
| GIBBS, EL; GIBBS, FA; RICH, CL | 1 |
| JIMENEZESPINOSA, L | 1 |
| KIORBOE, E | 1 |
| SPINKS, A; WARING, WS | 1 |
| SATOMI, M | 1 |
| FITZGIBBON, JP; LISHMAN, WA; WHITTY, CW | 1 |
| JONGMANS, JW | 1 |
| GIBSON, WE; GLEDHILL, SM; PORTER, PB; REID, LD | 1 |
| MEYER, HJ; MEYER-BURG, J | 1 |
| LORGE, M | 1 |
| KOFMAN, O | 1 |
| CHAREST, MP; DAVIS, MA; GAUDRY, R; HERR, F; THOMAS, RA; WINTHROP, SO | 1 |
| ANAND, MP | 1 |
| RYDER, RJ | 1 |
| CRAIG, WS; MACKINNON, JM | 1 |
| ZAKHARIIA, EA; ZAPADNIUK, VI | 1 |
| DEVERDIER, CH; HAMFELT, A; KILLANDER, A; MALERS, E | 1 |
| KOKENGE, R; KUTT, H; MCDOWELL, F | 1 |
| BALIER, C; MARCHAND, L; TEULIE, G | 1 |
| Carpay, JA; de Haan, GJ; van Donselaar, CA | 1 |
| Alkhamis, KA; Matheson, LE; Wurster, DE | 1 |
| Bell, G; Kendall, S; McCarthy, M; McCormick, D; Moran, NF; Nashef, L; Poole, K; Sander, J; Shorvon, SD; Solomon, J | 1 |
| Löscher, W; Potschka, H; Rieck, S; Rundfeldt, C; Tipold, A | 1 |
| Bode-Böger, SM; Martens-Lobenhoffer, J | 1 |
| Li, JH; Rui, JZ; Xiang, BR; Zhao, Y | 1 |
| Cantú, MD; Carrilho, E; Lacerda, CA; Lanças, FM; Queiroz, ME; Toso, DR | 1 |
| Dahl, ML; Kimland, E; Tomson, T | 1 |
| Edelbroek, PM; Vermeij, TA | 1 |
| Hamer, HM; Krämer, G; Strzelczyk, A; Vogt, H | 1 |
| Apeland, T; Frøyland, ES; Kristensen, O; Mansoor, MA; Strandjord, RE | 1 |
| Bocchicchio, M; Hauser, I; Horstmann, V; Huber, B; Jokeit, G; May, T; Meinert, T; Robertson, E; Schorlemmer, H; Schulz, L; Seidel, M; Wagner, W | 1 |
| Jensen, B; Lees, M; Regier, L | 1 |
| Klapková, E; Komárek, V; Tesfaye, H; Tesfayeová, A | 1 |
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| Duennbier, U; Hass, U; Massmann, G | 1 |
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| 't Jong, GW; Colantonio, D; Friedman, JN; Koren, G; Merlocco, A; Simpson, J; Tanoshima, R | 1 |
| Belinelli Silva, FA; Dos Santos, RC; Figueiredo, EC; Kakazu, AK; Santos, MG | 1 |
| de Baat, C; Vissink, A; Zweers, PGMA | 1 |
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64 review(s) available for phenobarbital and primidone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Interactions with antiepileptic drugs.
Topics: Acetaminophen; Acetazolamide; Anti-Anxiety Agents; Anticoagulants; Anticonvulsants; Carbamazepine; Diazepam; Drug Interactions; Furosemide; Gonadal Steroid Hormones; Griseofulvin; Humans; Phenobarbital; Phenytoin; Primidone; Thiazines; Urea; Valproic Acid; Vitamin D | 1977 |
[Pharmacotherapy of epilepsy. II].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Benzodiazepines; Carbamazepine; Epilepsy; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines; Valproic Acid | 1978 |
[Long-term anticonvulsant therapy (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chronic Disease; Clonazepam; Epilepsy; Ethosuximide; Humans; Long-Term Care; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1978 |
The pharmacological treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies, Myoclonic; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Ethosuximide; Female; Humans; Infant; Phenobarbital; Phenytoin; Pregnancy; Primidone; Spasms, Infantile; Status Epilepticus; Thyroid Gland | 1979 |
The medical treatment of epilepsy: initiation of drug therapy.
Topics: Adolescent; Adrenocorticotropic Hormone; Anticonvulsants; Bromides; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Epilepsy, Absence; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
Acute toxicity of antiepileptic drugs.
Topics: Acute Disease; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Dogs; Humans; Phenobarbital; Phenytoin; Poisoning; Primidone; Thiazines | 1975 |
Behavioural effects of anti-epileptic drugs.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Confusion; Disorders of Excessive Somnolence; Epilepsy; Ethosuximide; Humans; Hyperkinesis; Learning Disabilities; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Psychoses, Substance-Induced; Psychotropic Drugs; Thiazines | 1975 |
The determination of anticonvulsants in biological samples by use of high-pressure liquid chromatography.
Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Humans; Mathematics; Phenacetin; Phenobarbital; Phenytoin; Primidone; Spectrophotometry, Ultraviolet; Succinimides; Temperature | 1977 |
Drugs and children: methods for therapeutic monitoring.
Topics: Carbamazepine; Child; Child, Preschool; Chloramphenicol; Chromatography, Gas; Colorimetry; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Gentamicins; Humans; Immunoassay; Infant; Infant, Newborn; Monitoring, Physiologic; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Primidone; Quality Control; Spectrophotometry; Sulfonamides; Theophylline | 1977 |
[Laboratory controls in long-term treatment with anticonvulsive drugs (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Intestinal Absorption; Male; Phenobarbital; Phenytoin; Primidone; Time Factors; Valproic Acid | 1977 |
[Vitamin D: influence of anticonvulsant drugs on its metabolism].
Topics: Animals; Anticonvulsants; Dihydroxycholecalciferols; Humans; Hydroxycholecalciferols; Hydroxylation; Kidney; Liver; Phenobarbital; Phenytoin; Primidone; Vitamin D; Vitamin D Deficiency | 1977 |
[Antiepileptics during pregnancy and lactation. Pharmacokinetic data].
Topics: Anticonvulsants; Bromides; Carbamazepine; Clonazepam; Diazepam; Ethosuximide; Female; Fetus; Humans; Kinetics; Lactation; Maternal-Fetal Exchange; Nitrazepam; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1979 |
The medical treatment of epilepsy: maintenance of drug therapy.
Topics: Adolescent; Adult; Anticonvulsants; Biological Availability; Bromides; Carbamazepine; Child; Dextroamphetamine; Drug Administration Schedule; Epilepsy; Ethosuximide; Female; Humans; Infant; Male; Menstruation; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1979 |
Pharmacological and biochemical studies in epileptic fowl.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Brain; Chickens; Disease Models, Animal; Ethosuximide; Female; Humans; Male; Mutation; Phenobarbital; Phenytoin; Photic Stimulation; Primidone; Seizures; Valproic Acid | 1979 |
Clinical pharmacokinetics of anticonvulsants.
Topics: Administration, Oral; Adult; Aged; Aging; Animals; Anticonvulsants; Carbamazepine; Child; Clonazepam; Diazepam; Drug Interactions; Ethosuximide; Female; Humans; Hydantoins; Infant, Newborn; Injections, Intramuscular; Injections, Intravenous; Intestinal Absorption; Kidney Diseases; Kinetics; Liver Diseases; Milk; Molecular Biology; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1976 |
[Neurotoxicity of antiepileptic drugs].
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Ethosuximide; Humans; Male; Nervous System; Nervous System Diseases; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1992 |
[The effect of monotherapy on concentration of selected blood serum hormones and upon cognitive function of children with epilepsy].
Topics: Adolescent; Carbamazepine; Child; Cognition; Epilepsy; Female; Follow-Up Studies; Humans; Male; Phenobarbital; Primidone; Psychomotor Performance; Regression Analysis; Thyroid Hormones | 1992 |
The pharmacological management of essential tremor.
Topics: Adrenergic beta-Antagonists; Ethanol; Humans; Phenobarbital; Primidone; Propranolol; Tremor | 1986 |
Carbamazepine drug interactions.
Topics: Carbamazepine; Cimetidine; Dextropropoxyphene; Drug Interactions; Erythromycin; Humans; Isoniazid; Lithium; Phenobarbital; Phenytoin; Primidone; Protein Binding; Troleandomycin; Valproic Acid; Warfarin | 1986 |
Antiepileptic drugs in adolescents.
Topics: Adaptation, Psychological; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Interactions; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Sports; Valproic Acid | 1987 |
[Neurotraumatology and post-traumatic epilepsy. Prevention, treatment and long-term follow-up. Barbexaclone + phenobarbital (maliasin) versus diphenylhydantoin, phenobarbital, primidone, carbamazepine].
Topics: Adolescent; Adult; Anticonvulsants; Brain Injuries; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1987 |
Use of barbiturates and benzodiazepines in treatment of epilepsy.
Topics: Adult; Barbiturates; Benzodiazepines; Child; Clonazepam; Clorazepate Dipotassium; Diazepam; Epilepsy; Humans; Infant; Infant, Newborn; Lorazepam; Phenobarbital; Primidone | 1986 |
Pharmacokinetics of anti-epileptic drugs in the dog: a review.
Topics: Animals; Anticonvulsants; Blood Proteins; Carbamazepine; Clonazepam; Diazepam; Dog Diseases; Dogs; Epilepsy; Ethosuximide; Kinetics; Phenobarbital; Phenytoin; Primidone; Species Specificity; Trimethadione; Valproic Acid | 1985 |
Anticonvulsants, folic acid, and epilepsy.
Topics: Anemia, Macrocytic; Animals; Anticonvulsants; Blood-Brain Barrier; Chemical Phenomena; Chemistry; Epilepsies, Partial; Epilepsy; Folic Acid; Humans; Leucovorin; Mice; Phenobarbital; Phenytoin; Primidone; Rabbits; Rats; Seizures | 1973 |
Usefulness of blood levels of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Chromatography, Gas; Dextropropoxyphene; Diazepam; Dicumarol; Disulfiram; Drug Interactions; Epilepsy; Ethosuximide; Humans; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Prochlorperazine; Sulfamethizole; Sulfaphenazole; Thiazines | 1974 |
Diagnosis and treatment of epilepsy: overview and general principles.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Histamine H1 Antagonists; Humans; Hydantoins; Hypnotics and Sedatives; Infant, Newborn; Myoclonus; Phenobarbital; Phenytoin; Primidone; Sleep | 1974 |
Relation of laboratory evaluation to clinical effectiveness of antiepileptic drugs.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzazepines; Clinical Trials as Topic; Drug Tolerance; Electroencephalography; Electroshock; Epilepsy; Ethosuximide; Humans; Pentylenetetrazole; Phenobarbital; Phenytoin; Primidone; Seizures; Trimethadione; Urea | 1969 |
A basic approach to the understanding of seizures and the mechanism of action and metabolism of anticonvulsants.
Topics: Acetylcholine; Aminobutyrates; Anticonvulsants; Calcium; Cell Membrane Permeability; Depression, Chemical; Diazepam; Epilepsy; Ethosuximide; Humans; Membrane Potentials; Mephobarbital; Neural Inhibition; Neurons; Phenobarbital; Phenytoin; Primidone; Seizures; Stimulation, Chemical; Synapses; Synaptic Transmission | 1973 |
Toxic effects of anticonvulsants: general principles.
Topics: Adrenocorticotropic Hormone; Adult; Anticonvulsants; Benzodiazepinones; Body Surface Area; Body Weight; Carbamazepine; Child; Chlorobenzenes; Diagnosis, Differential; Diazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Half-Life; Humans; Nitro Compounds; Phenobarbital; Phenytoin; Primidone; Succinimides; Tranquilizing Agents; Trimethadione | 1974 |
The management of children with epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epilepsy; Ethosuximide; Humans; Infant; Infant, Newborn; Phenobarbital; Phenytoin; Primidone; Thiazines | 1970 |
Adverse hematologic effects of drugs.
Topics: Anemia, Hemolytic; Anemia, Macrocytic; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents; Aspirin; Blood Platelet Disorders; Drug-Related Side Effects and Adverse Reactions; Female; Glucosephosphate Dehydrogenase Deficiency; Hematologic Diseases; Hematopoiesis; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Infant, Newborn; Infant, Newborn, Diseases; Phenobarbital; Phenytoin; Pregnancy; Primidone; Serum Sickness; Splenomegaly; Thrombocytopenia; Tranquilizing Agents | 1972 |
Pharmacology of anticonvulsants.
Topics: Animals; Anticonvulsants; Child; Drug Interactions; Electroencephalography; Ethosuximide; Half-Life; Humans; Liver; Mephobarbital; Phenobarbital; Phenytoin; Primidone | 1972 |
Cerebrospinal folate levels in epileptics and their response to folate therapy.
Topics: Anticonvulsants; Blood-Brain Barrier; Clinical Trials as Topic; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Tetrahydrofolates; Vitamin B 12 | 1974 |
The use of blood levels of antiepileptic drugs in clinical practice.
Topics: Administration, Oral; Adult; Anticonvulsants; Biopharmaceutics; Carbamazepine; Child; Drug Tolerance; Epilepsy; Ethosuximide; Humans; Injections, Intramuscular; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Primidone; Sleep; Time Factors | 1974 |
Pharmacodynamic and pharmacokinetic measurements of antiepileptic drugs.
Topics: Anticonvulsants; Chromatography, Gas; Dose-Response Relationship, Drug; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Trimethadione | 1974 |
Osteomalacia and anticonvulsant drugs.
Topics: Alkaline Phosphatase; Anticonvulsants; Calcium; Epilepsy; Folic Acid; Humans; Liver; Osteomalacia; Phenobarbital; Phenytoin; Primidone; Vitamin D | 1971 |
[General review of the present therapy of epilepsy].
Topics: Anticonvulsants; Barbiturates; Chlordiazepoxide; Diazepam; Epilepsy; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Succinimides | 1971 |
Reassessment of the concept of a therapeutic range of anticonvulsant plasma levels.
Topics: Anticonvulsants; Binding Sites; Brain Chemistry; Carbamazepine; Drug Therapy, Combination; Genetic Variation; Half-Life; Humans; Kinetics; Phenobarbital; Phenytoin; Primidone; Time Factors | 1983 |
Diagnosis and treatment of epilepsy.
Topics: Automatism; Benzodiazepines; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Ethosuximide; Humans; Muscle Tonus; Phenobarbital; Phenytoin; Primidone; Telemetry; Valproic Acid | 1983 |
The clinical pharmacology of antiepileptic drugs.
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Ethosuximide; Female; Half-Life; Humans; Intestinal Absorption; Kidney; Kidney Diseases; Kinetics; Liver Diseases; Phenobarbital; Phenytoin; Pregnancy; Primidone; Protein Binding; Tissue Distribution; Trimethadione; Valproic Acid | 1984 |
Interactions between anticonvulsants and other commonly prescribed drugs.
Topics: Analgesics; Anti-Infective Agents; Anticoagulants; Anticonvulsants; Benzodiazepines; Biotransformation; Carbamazepine; Drug Interactions; Humans; Intestinal Absorption; Kinetics; Phenobarbital; Phenytoin; Primidone; Protein Binding; Psychotropic Drugs; Succinimides; Sulfonamides; Tissue Distribution; Valproic Acid | 1984 |
Clinical pharmacokinetics of antiepileptic drugs in adults.
Topics: Adult; Aging; Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Disease; Ethosuximide; Female; Humans; Kinetics; Phenobarbital; Phenytoin; Pregnancy; Primidone; Saliva; Valproic Acid | 1980 |
Pharmacological principles in the long-term treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Kinetics; Long-Term Care; Phenobarbital; Phenytoin; Primidone; Succinimides; Valproic Acid | 1981 |
[The post-traumatic epilepsy (author's transl)].
Topics: Brain Concussion; Brain Injuries; Brain Neoplasms; Carbamazepine; Diagnostic Errors; Electroencephalography; Ependymoma; Epilepsy, Post-Traumatic; Humans; Phenobarbital; Phenytoin; Primidone; Skull | 1981 |
Antiepileptic therapeutic drug monitoring.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1981 |
Drug interactions with valproic acid.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Dose-Response Relationship, Drug; Drug Interactions; Ethosuximide; Fatty Acids, Nonesterified; Humans; Kinetics; Phenobarbital; Phenytoin; Primidone; Salicylates; Valproic Acid | 1982 |
Seizure disorders.
Topics: Animals; Cat Diseases; Cats; Diagnosis, Differential; Diazepam; Dog Diseases; Dogs; Epilepsy; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Recurrence; Seizures; Succinimides | 1980 |
Essential tremor: an overview.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Anxiety Agents; Benzodiazepines; Brain; Diagnosis, Differential; Ethanol; Humans; Parkinson Disease, Secondary; Peripheral Nerves; Phenobarbital; Primidone; Tremor | 1994 |
Clinical pharmacokinetics of antiepileptic drugs in paediatric patients. Part I: Phenobarbital, primidone, valproic acid, ethosuximide and mesuximide.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Ethosuximide; Humans; Infant; Infant, Newborn; Phenobarbital; Primidone; Succinimides; Valproic Acid | 1995 |
Clinically significant pharmacokinetic drug interactions with carbamazepine. An update.
Topics: Analgesics, Non-Narcotic; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents; Carbamazepine; Drug Interactions; Ethosuximide; Felbamate; Humans; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Valproic Acid | 1996 |
Antiepileptic drug review: part 1.
Topics: Anticonvulsants; Biological Availability; Carbamazepine; Drug Interactions; Half-Life; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1998 |
Anticonvulsant therapy in small animals.
Topics: Acetates; Amines; Animals; Anticonvulsants; Bromides; Clonazepam; Clorazepate Dipotassium; Cyclohexanecarboxylic Acids; Diazepam; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Mephenytoin; Pentobarbital; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Seizures; Valproic Acid | 1998 |
Standards of laboratory practice: antiepileptic drug monitoring. National Academy of Clinical Biochemistry.
Topics: Anticonvulsants; Blood Specimen Collection; Carbamazepine; Drug Interactions; Drug Monitoring; Humans; Phenobarbital; Phenytoin; Primidone; Quality Control; Valproic Acid | 1998 |
Antiepileptic drug hypersensitivity syndrome.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cross Reactions; Diagnosis, Differential; Drug Hypersensitivity; Epilepsy; Exanthema; Humans; Incidence; Male; Phenobarbital; Phenytoin; Primidone; Syndrome | 1998 |
Population pharmacokinetics of lamotrigine adjunctive therapy in adults with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Male; Metabolic Clearance Rate; Middle Aged; Phenobarbital; Phenytoin; Primidone; Randomized Controlled Trials as Topic; Retrospective Studies; Triazines | 1999 |
[Febrile convulsions, Treatment and prognosis].
Topics: Analgesics, Non-Narcotic; Anticonvulsants; Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Phenobarbital; Primidone; Prognosis; Recurrence; Seizures, Febrile; Time Factors; Valproic Acid | 2001 |
PROTOZOA AS TOXICOLOGIC TOOLS.
Topics: Anti-Allergic Agents; Antimalarials; Antimetabolites; Antineoplastic Agents; Benzopyrenes; Carcinogens; Euglena; Eukaryota; Histamine H1 Antagonists; Paramecium; Phenobarbital; Primidone; Quinolines; Research; Sterols; Tetrahymena; Thalidomide; Toxicology; Urethane | 1964 |
ANTICONVULSANT DRUGS.
Topics: Acetazolamide; Acetylcholine; Amides; Aminobutyrates; Anticonvulsants; Brain; Chemistry, Pharmaceutical; Dopamine; Drug Therapy; Epilepsy; Humans; Hydantoins; Norepinephrine; Pharmacology; Phenobarbital; Primidone; Propylene Glycols; Pyrrolidinones; Research; Serotonin; Succinimides | 1963 |
[Antiepileptic primidone shortly to be withdrawn from sale: change medication now].
Topics: Anticonvulsants; Drug and Narcotic Control; Epilepsy; Humans; Phenobarbital; Primidone; Substance Withdrawal Syndrome | 2003 |
Therapeutic monitoring of antiepileptic drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Drug Monitoring; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 2007 |
A child exposed to primidone not prescribed for her.
Topics: Animals; Anticonvulsants; Child; Epilepsy; Female; Gastrointestinal Diseases; Humans; Phenobarbital; Primidone; Prohibitins; Rats; Rats, Sprague-Dawley; Retrospective Studies | 2013 |
[Medicaments and oral healthcare. Proliferation of the gingiva].
Topics: Anticonvulsants; Carbamazepine; Cell Proliferation; Ethosuximide; Gingiva; Humans; Netherlands; Oral Hygiene; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 2018 |
Concentrations of antiseizure medications in breast milk of lactating women with epilepsy: A systematic review with qualitative synthesis.
Topics: Anticonvulsants; Breast Feeding; Epilepsy; Ethosuximide; Female; Humans; Infant; Lactation; Milk, Human; Phenobarbital; Primidone | 2022 |
34 trial(s) available for phenobarbital and primidone
| Article | Year |
|---|---|
One drug (phenytoin) in the treatment of epilepsy.
Topics: Adolescent; Adult; Aged; Drug Evaluation; Drug Therapy, Combination; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Placebos; Primidone; Time Factors | 1976 |
A comparison of phenobarbitone and primidone in the control of seizures in chronic epilepsy [proceedings].
Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Epilepsy; Humans; Middle Aged; Phenobarbital; Primidone; Seizures | 1979 |
Paracetamol disposition in normal subjects and in patients treated with antiepileptic drugs.
Topics: Acetaminophen; Administration, Oral; Adult; Anticonvulsants; Biological Availability; Carbamazepine; Female; Humans; Injections, Intravenous; Male; Phenobarbital; Phenytoin; Primidone | 1979 |
Clinical evaluation of eterobarb, a new anticonvulsant drug.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Clinical Trials as Topic; Drug Evaluation; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Primidone; Psychological Tests | 1975 |
Continuous phrophylcatic anticonvulsants in selected childrens with febrile convulsions.
Topics: Child; Child, Preschool; Clinical Trials as Topic; Female; Fever; Follow-Up Studies; Humans; Infant; Male; Phenobarbital; Primidone; Recurrence; Seizures | 1975 |
Interaction of phenytoin and primidone.
Topics: Adolescent; Adult; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1975 |
Quantitative comparison of barbiturates in essential hand and head tremor.
Topics: Aged; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hand; Head; Humans; Male; Microcomputers; Middle Aged; Neurologic Examination; Phenobarbital; Primidone; Signal Processing, Computer-Assisted; Tremor | 1991 |
Aspects of compliance: taking drugs and keeping clinic appointments.
Topics: Adolescent; Adult; Anticonvulsants; Appointments and Schedules; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Epilepsies, Partial; Epilepsy; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Outpatient Clinics, Hospital; Patient Compliance; Phenobarbital; Phenytoin; Primidone; Prospective Studies | 1988 |
Double-blind comparison of primidone and phenobarbital in essential tremor.
Topics: Clinical Trials as Topic; Double-Blind Method; Humans; Phenobarbital; Primidone; Tremor | 1988 |
Results of a nationwide Veterans Administration Cooperative Study comparing the efficacy and toxicity of carbamazepine, phenobarbital, phenytoin, and primidone.
Topics: Adult; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Prospective Studies | 1987 |
Barbiturates reduce human cerebral glucose metabolism.
Topics: Adult; Brain; Glucose; Humans; Phenobarbital; Primidone; Tomography, Emission-Computed | 1986 |
Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures.
Topics: Adolescent; Adult; Aged; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Epilepsies, Partial; Epilepsy; Erectile Dysfunction; Female; Follow-Up Studies; Humans; Leukocyte Count; Lupus Vulgaris; Lymphoma; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Psychoses, Substance-Induced | 1985 |
Efficacy of primidone in essential tremor.
Topics: Dose-Response Relationship, Drug; Humans; Male; Middle Aged; Phenobarbital; Primidone; Propranolol; Tremor | 1986 |
Influence of folic acid on blood-phenytoin levels.
Topics: Adult; Anticonvulsants; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1971 |
Evaluation of albutoin as an antiepileptic drug.
Topics: Adolescent; Adult; Allyl Compounds; Analysis of Variance; Anticonvulsants; Appetite; Biopharmaceutics; Chromatography, Thin Layer; Clinical Trials as Topic; Drug Evaluation; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Female; Humans; Hydantoins; Male; Middle Aged; Nausea; Phenobarbital; Phenytoin; Placebos; Primidone; Spectrophotometry; Statistics as Topic; Thiohydantoins; Time Factors; Vomiting | 1974 |
"Anticonvulsant action" of vitamin D in epileptic patients? A controlled pilot study.
Topics: Adolescent; Adult; Alkaline Phosphatase; Anticonvulsants; Calcium; Child; Clinical Trials as Topic; Epilepsy; Epilepsy, Tonic-Clonic; Female; Humans; Magnesium; Male; Phenobarbital; Phenytoin; Placebos; Primidone; Vitamin D | 1974 |
Relation of laboratory evaluation to clinical effectiveness of antiepileptic drugs.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzazepines; Clinical Trials as Topic; Drug Tolerance; Electroencephalography; Electroshock; Epilepsy; Ethosuximide; Humans; Pentylenetetrazole; Phenobarbital; Phenytoin; Primidone; Seizures; Trimethadione; Urea | 1969 |
Folate therapy in epilepsy. A controlled study.
Topics: Clinical Trials as Topic; Cognition; Epilepsy; Evaluation Studies as Topic; Folic Acid; Humans; Leucovorin; Personality; Phenobarbital; Phenytoin; Primidone; Psychological Tests | 1973 |
A controlled trial on Ro 5-4023 (clonazepam) in the treatment of psychomotor epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepinones; Carbamazepine; Child; Chlorobenzenes; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Fatigue; Female; Humans; Male; Middle Aged; Nitro Compounds; Phenobarbital; Phenytoin; Placebos; Primidone; Time Factors | 1973 |
Cerebrospinal folate levels in epileptics and their response to folate therapy.
Topics: Anticonvulsants; Blood-Brain Barrier; Clinical Trials as Topic; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Tetrahydrofolates; Vitamin B 12 | 1974 |
Incidence of anticonvulsant osteomalacia and effect of vitamin D: controlled therapeutic trial.
Topics: Adult; Aged; Alkaline Phosphatase; Anticonvulsants; Bone and Bones; Calcium; Creatinine; Epilepsy; Female; Humans; Male; Mathematics; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Placebos; Primidone; Radiometry; Vitamin D | 1973 |
Subnormal serum folate due to anticonvulsive therapy. A double-blind study of the effect of folic acid treatment in patients with drug-induced subnormal serum folates.
Topics: Adult; Anticonvulsants; Clinical Trials as Topic; Epilepsy; Erythrocyte Count; Female; Folic Acid; Hematocrit; Hemoglobinometry; Humans; Male; Phenobarbital; Phenytoin; Placebos; Primidone | 1970 |
The metabolic conversion of primidone (Mysoline) to phenobarbitone in patients under long-term treatment. An attempt to estimate the independent effect of primidone.
Topics: Adult; Behavior; Clinical Trials as Topic; Drug Synergism; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Male; Middle Aged; Phenobarbital; Primidone | 1967 |
Relative anticonvulsant potency of primidone; a double blind comparison.
Topics: Clinical Trials as Topic; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1966 |
Single drug therapy for intractable epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Epilepsy, Temporal Lobe; Humans; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1983 |
Historical perspective on the choice of antiepileptic drugs for the treatment of seizures in adults.
Topics: Adult; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Epilepsy; History, 20th Century; Humans; Phenobarbital; Phenytoin; Primidone; Seizures | 1983 |
Benign familial tremor treated with primidone.
Topics: Female; Humans; Male; Phenobarbital; Primidone; Tremor | 1981 |
Systematic testing of medical intractability for carbamazepine, phenytoin, and phenobarbital or primidone in monotherapy for patients considered for epilepsy surgery.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Epilepsy; Follow-Up Studies; Humans; Infant; Middle Aged; Patient Selection; Phenobarbital; Phenytoin; Primidone; Quality of Life; Treatment Failure; Treatment Outcome | 1996 |
Antiepileptic drug treatment in pregnancy: drug side effects in the neonate and neurological outcome.
Topics: Anticonvulsants; Child; Drug Monitoring; Epilepsy; Female; Follow-Up Studies; Humans; Nervous System Diseases; Neurologic Examination; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Primidone; Valproic Acid | 1996 |
Outcome evaluation of gabapentin as add-on therapy for partial seizures. "NEON" Study Investigators Group. Neurontin Evaluation of Outcomes in Neurological Practice.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neurologic Examination; Phenobarbital; Phenytoin; Primidone; Quality of Life; Valproic Acid | 1998 |
Prevention of febrile convulsions with dipropylacetate (Depakine).
Topics: Anticonvulsants; Child, Preschool; Humans; Phenobarbital; Primidone; Seizures, Febrile; Valproic Acid | 1975 |
Does withdrawal of different antiepileptic drugs have different effects on seizure recurrence? Further results from the MRC Antiepileptic Drug Withdrawal Study.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Combinations; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Proportional Hazards Models; Recurrence; Risk Assessment; Seizures; Substance Withdrawal Syndrome; Valproic Acid | 1999 |
The "forgotten" cross-tolerance between phenobarbital and primidone: it can prevent acute primidone-related toxicity.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Child; Child, Preschool; Dizziness; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Epilepsies, Partial; Female; Follow-Up Studies; Hospitalization; Humans; Male; Middle Aged; Phenobarbital; Premedication; Primidone; Treatment Outcome | 2000 |
[Evaluation of antiepileptic therapy during pregnancy].
Topics: Adult; Anticonvulsants; Apgar Score; Drug Therapy, Combination; Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Primidone; Valproic Acid | 2002 |
573 other study(ies) available for phenobarbital and primidone
| Article | Year |
|---|---|
Synthesis and anticonvulsant activity of some new 2-substituted 3-aryl-4(3H)-quinazolinones.
Topics: Animals; Anticonvulsants; Bicuculline; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Electroshock; Lethal Dose 50; Male; Methaqualone; Mice; Molecular Structure; Pentylenetetrazole; Picrotoxin; Pyridines; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship; Strychnine | 1990 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Interactions between anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Humans; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Thiazines | 1975 |
Prognosis and therapy of complex partial seizures with barbiturates, hydantoins, and other drugs.
Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal Lobe; Hydantoins; Mephenytoin; Phenobarbital; Phenytoin; Primidone; Prognosis; Succinimides; Thiazines; Valproic Acid | 1975 |
Salivary levels of anticonvulsants: a practical approach to drug monitoring.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Primidone; Saliva | 1977 |
Simultaneous measurement of phenobarbital, phenytoin, primidone, ethosuximide, and carbamazepine in serum by high-pressure liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Hot Temperature; Humans; Hydrogen-Ion Concentration; Methods; Phenobarbital; Phenytoin; Primidone | 1977 |
Measurement of anti-epileptic drugs in plasma by gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Phenobarbital; Phenytoin; Primidone; Quality Control; Thiazines | 1977 |
The extraction of antiepileptic drugs. Model study on partition coefficients.
Topics: Anticonvulsants; Carbamazepine; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Primidone; Solvents; Spectrum Analysis | 1978 |
An improved method for preparation of samples for the simultaneous assay of some antiepileptic drugs by gas-liquid chromatography.
Topics: Barbiturates; Body Fluids; Chromatography, Gas; Female; Humans; Milk, Human; Phenobarbital; Phenytoin; Pregnancy; Primidone; Saliva | 1978 |
[Drug interactions in antiepileptic combination therapy].
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Enzyme Induction; Humans; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Thiazines; Time Factors; Urea; Valproic Acid | 1979 |
Use of anticonvulsant drugs.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
Gas-liquid chromatography of undervatized drugs after chromatographic extraction from blood.
Topics: Amobarbital; Anticonvulsants; Blood Chemical Analysis; Carbamazepine; Chromatography, Gas; Gastric Juice; Glutethimide; Humans; Hypnotics and Sedatives; Methaqualone; Phenobarbital; Phenytoin; Piperidones; Primidone; Secobarbital | 1979 |
Amines, anticonvulsants, and epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Brain; Chromatography, Gas; Drug Therapy, Combination; Epilepsy; Fluorometry; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Middle Aged; Phenobarbital; Phenylacetates; Phenytoin; Primidone | 1975 |
Letter: Bioavailability of drugs after intramuscular injection.
Topics: Absorption; Administration, Oral; Adult; Biological Availability; Biotransformation; Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Injections, Intramuscular; Male; Phenobarbital; Phenytoin; Primidone | 1975 |
EEG changes after withdrawal of medication in epileptic patients.
Topics: Adult; Anticonvulsants; Brain; Electroencephalography; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Substance Withdrawal Syndrome | 1975 |
Interactions of antiepileptic drugs.
Topics: Anti-Infective Agents; Anticonvulsants; Benzodiazepines; Biotransformation; Blood Proteins; Carbamazepine; Dextropropoxyphene; Dicumarol; Disulfiram; Drug Interactions; Ethosuximide; Humans; Intestinal Absorption; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenothiazines; Phenytoin; Primidone; Protein Binding; Thiazines | 1975 |
The fetal hydantoin syndrome.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Child, Preschool; Developmental Disabilities; Epilepsy; Female; Fetus; Fingers; Growth Disorders; Humans; Hydantoins; Hypertelorism; Infant; Intellectual Disability; Male; Mephobarbital; Motor Skills; Mouth Abnormalities; Myoclonus; Nails, Malformed; Phenobarbital; Pregnancy; Pregnancy Complications; Primidone; Succinimides; Syndrome; Teratogens; Toes | 1975 |
The effect of phenytoin and ethosuximide on primidone metabolism in patients with epilepsy.
Topics: Drug Interactions; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Saliva | 1975 |
How doctors deal with epilepsy.
Topics: Adolescent; Adult; Aged; Automobile Driving; Diazepam; Drug Therapy, Combination; Electroencephalography; Epilepsy; Evaluation Studies as Topic; Follow-Up Studies; Humans; London; Middle Aged; Phenobarbital; Phenytoin; Primidone; Quality of Health Care; Referral and Consultation | 1977 |
Therapeutic and pharmacokinetic effects of increasing phenytoin in chronic epileptics on multiple drug therapy.
Topics: Adult; Biological Availability; Chronic Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1976 |
Hepatitis and anticonvulsant therapy.
Topics: Acute Disease; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Epilepsy; Humans; Male; Middle Aged; Phenobarbital; Primidone | 1978 |
In vivo interaction of anticonvulsant drugs. The mathematical correlation of plasma levels of anticonvulsant drugs in epileptic patients.
Topics: Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Intestinal Absorption; Phenobarbital; Phenytoin; Primidone | 1978 |
Anticonvulsant drugs and cancer. A cohort study in patients with severe epilepsy.
Topics: Adolescent; Adult; Brain Neoplasms; Child; England; Epilepsy; Female; Follow-Up Studies; Humans; Male; Neoplasms; Phenobarbital; Phenytoin; Primidone; Risk; Sex Ratio; Spinal Cord Neoplasms; Time Factors; Wales | 1979 |
Primidone metabolism in renal insufficiency and acute intoxication.
Topics: Acute Disease; Adult; Aged; Biotransformation; Female; Humans; Kidney Failure, Chronic; Phenobarbital; Phenylethylmalonamide; Primidone; Suicide, Attempted | 1979 |
[Clinical picture and basis for treating brain stem epilepsy].
Topics: Adolescent; Adult; Anticonvulsants; Brain Stem; Diazepam; Epilepsies, Myoclonic; Epilepsy; Female; Humans; Male; Meprobamate; Middle Aged; Phenobarbital; Primidone | 1978 |
[Blood level of antiepileptic drugs and therapeutic effect in mono- and polytherapy (author's transl)].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Humans; Infant; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1978 |
Pharmacological interactions of mesuximide with phenobarbital and phenytoin in hospitalized epileptic patients.
Topics: Adolescent; Adult; Child; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy, Absence; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Succinimides | 1979 |
[Primary generalized epilepsy in childhood. Clinico-statistical study].
Topics: Age Factors; Anticonvulsants; Child; Child, Preschool; Clonazepam; Electroencephalography; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Hydantoins; Phenobarbital; Primidone | 1979 |
Seizure activity and anticonvulsant drug concentration.
Topics: Anticonvulsants; Child; Circadian Rhythm; Diazepam; Dose-Response Relationship, Drug; Drug Administration Schedule; Electroencephalography; Epilepsy; Female; Half-Life; Humans; Male; Phenobarbital; Phenytoin; Primidone; Sleep Stages; Sleep, REM; Telemetry | 1975 |
[Effect of drugs on electroclinical types of epileptic seizures in Lennox-Gastaut syndrome].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Child; Child, Preschool; Clonazepam; Diazepam; Electroencephalography; Epilepsy; Female; Humans; Infant; Male; Nitrazepam; Phenobarbital; Phenytoin; Primidone; Seizures; Spasms, Infantile; Syndrome | 1977 |
Organic nitrogen-selective detector used in gas-chromatographic determination of some anticonvulsant and barbiturate drugs in plasma and tissues.
Topics: Animals; Anticonvulsants; Barbiturates; Brain Chemistry; Carbamazepine; Chromatography, Gas; Horses; Humans; Hydantoins; Methods; Nitrogen; Phenobarbital; Phenytoin; Primidone; Time Factors | 1975 |
A primate model for testing anticonvulsant drugs.
Topics: Allyl Compounds; Animals; Anticonvulsants; Carbamazepine; Chromatography, Gas; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation; Drug Evaluation, Preclinical; Electroencephalography; Ethosuximide; Female; Glycine; Male; Myoclonus; Papio; Phenobarbital; Phenytoin; Photic Stimulation; Primidone; Seizures; Thiazines | 1975 |
Involuntary movements caused by phenytoin intoxication in epileptic patients.
Topics: Adult; Chlorpheniramine; Diazepam; Drug Interactions; Drug Therapy, Combination; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Movement Disorders; Phenobarbital; Phenytoin; Primidone; Thiazines | 1975 |
[Effects of combination of anti-epileptic drugs].
Topics: Adrenergic beta-Antagonists; Anticonvulsants; Benzodiazepines; Carbamazepine; Digitoxin; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Lithium; Phenobarbital; Phenytoin; Primidone; Thiazines; Tolbutamide; Tranquilizing Agents | 1975 |
Automated computer analysis for enzyme-multiplied immunological techniques.
Topics: Computers; Dose-Response Relationship, Immunologic; Evaluation Studies as Topic; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone | 1977 |
Anticonvulsants in serum, determined with a fully mechanized enzyme analyzer.
Topics: Evaluation Studies as Topic; Glucosephosphate Dehydrogenase; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone | 1977 |
Use of saliva in therapeutic drug monitoring.
Topics: Antipyrine; Caffeine; Ethosuximide; Gas Chromatography-Mass Spectrometry; Humans; Immunoenzyme Techniques; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Primidone; Saliva; Theophylline | 1977 |
Drug interactions during anticonvulsant therapy in childhood: diphenylhydantoin, primidone, phenobarbitone, clonazepam, nitrazepam, carbamazepin and dipropylacetate.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Nitrazepam; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1977 |
Enzyme immunoassay of phenobarbital phenytoin, and primidone with the ABA-100 bichromatic analyzer.
Topics: Autoanalysis; Humans; Immunoenzyme Techniques; Methods; Phenobarbital; Phenytoin; Primidone | 1977 |
Determination of phenobarbital and phenytoin in serum by a mechanized enzyme immunoassay (EMIT) in comparison with a gas-liquid chromatographic method.
Topics: Child; Chromatography, Gas; Chromatography, Liquid; Female; Humans; Immunoenzyme Techniques; Methods; Phenobarbital; Phenytoin; Primidone | 1977 |
[Plasma levels of anticonvulsants. Experiences with routine plasma level determination of 6 different anticonvulsants].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1978 |
Long-term use of the major anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Time Factors; Valproic Acid | 1978 |
[The studies on the antiepileptic drug estimation by means of EMIT-AED (author's transl)].
Topics: Enzyme-Linked Immunosorbent Assay; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Reagent Kits, Diagnostic | 1978 |
[Study of metabolic activation of chemical compounds by using microorganisms. I. Effect of inducers of microsomal systems].
Topics: Barbiturates; Benzidines; Biotransformation; Cyclophosphamide; Drug Interactions; Hydrocortisone; Microsomes; Morpholines; Mutagens; Nitroso Compounds; Phenobarbital; Primidone; Psychotropic Drugs; Salmonella typhimurium | 1978 |
Consecutive gas chromatographic determination of phenytoin, phenobarbital, primidone, phenylethylmalondiamide, carbamazepine, trimethadione, dimethadione, ethosuximide, and valproate from the same serum specimen.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Dimethadione; Ethosuximide; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Trimethadione; Valproic Acid | 1978 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Status Epilepticus; Valproic Acid | 1979 |
Recent advances in drug therapy for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Drug Interactions; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
Evaluation of automated enzyme immunoassays for five anticonvulsants and theophylline adapted to a centrifugal analyzer.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Theophylline | 1979 |
The use of antiepileptic drugs.
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
[The serum concentration of anticonvulsants -- pharmacokinetic findings and practical therapeutic applications (author's transl)].
Topics: Antacids; Anticonvulsants; Biological Availability; Carbamazepine; Chromatography, Gas; Clonazepam; Dosage Forms; Ethosuximide; Half-Life; Humans; Immunoenzyme Techniques; Intestinal Absorption; Phenobarbital; Phenytoin; Primidone; Seizures; Valproic Acid | 1979 |
Accuracy of serum anticonvulsant measurements. A comparison of enzyme multiplied immunoassay technique and gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone | 1979 |
High pressure liquid chromatography for simultaneous analysis of anticonvulsants: comparison with EMIT system.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Immunoenzyme Techniques; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Reference Standards | 1979 |
[Clinical study of serum level of dipropylacetic acid sodium (Depakene) by gaschromatography (author's transl)].
Topics: Adolescent; Adult; Child; Child, Preschool; Chromatography, Gas; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Female; Humans; Male; Middle Aged; Phenobarbital; Primidone; Valerates; Valproic Acid | 1977 |
[The effect of primidone treatment of thyroid hormones in epileptic children and adolescents (author's transl)].
Topics: Adolescent; Child; Enzyme Induction; Epilepsy; Female; Humans; Iodine; Liver; Male; Phenobarbital; Primidone; Thyroid Gland; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Time Factors | 1977 |
Medical treatment of epilepsy: Part II.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Calcium; Child; Drug Interactions; Epilepsy; Epilepsy, Tonic-Clonic; Female; Gingival Hyperplasia; Humans; Hyperkinesis; Phenobarbital; Phenytoin; Pregnancy; Primidone; Status Epilepticus | 1978 |
Epilepsy among parents of children with facial clefts.
Topics: Anticonvulsants; Cleft Lip; Cleft Palate; Epilepsy; Female; Humans; Male; Parents; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone | 1979 |
[Significance of pharmacogenic liver reactions for metabolism of endogenous and exogenous substances].
Topics: Carbamazepine; Diazepam; Drug-Related Side Effects and Adverse Reactions; Female; Fenoterol; Humans; Liver; Phenobarbital; Phenytoin; Pregnancy; Primidone | 1979 |
Serum anticonvulsant monitoring by liquid chromatography with a methanolic mobile phase.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1979 |
[Neutropenia in epilepsy patients].
Topics: Adolescent; Adult; Agranulocytosis; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Leukopenia; Male; Middle Aged; Neutropenia; Phenobarbital; Primidone | 1979 |
Biochemical variables related to calcium metabolism in epileptics.
Topics: Aged; Alkaline Phosphatase; Anticonvulsants; Calcium; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Phosphates; Primidone | 1979 |
Mucocutaneous eruptions due to antiepileptic drug therapy in children.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Erythema Multiforme; Female; Humans; Male; Mephenytoin; Phenobarbital; Phenytoin; Primidone; Stevens-Johnson Syndrome | 1979 |
[The frequency of adult anticonvulsant osteomalacia in relation to duration of therapy and dosage of anticonvulsants (author's transl)].
Topics: Adult; Alkaline Phosphatase; Calcium; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Humans; Hydantoins; Hydroxycholecalciferols; Male; Middle Aged; Osteomalacia; Phenobarbital; Phosphates; Primidone | 1979 |
Improved determination of phenobarbital, primidone, and phenytoin by use of a preparative instrument for extraction, followed by gas chromatography.
Topics: Autoanalysis; Chromatography, Gas; Evaluation Studies as Topic; Humans; Phenobarbital; Phenytoin; Primidone | 1979 |
[Drug therapy of epilepsy with control of the serum level of anti-epileptic agents].
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Prospective Studies | 1979 |
Single-dose pharmacokinetics and anticonvulsant efficacy of primidone in mice.
Topics: Animals; Biotransformation; Brain Chemistry; Dose-Response Relationship, Drug; Female; Mice; Phenobarbital; Phenylethylmalonamide; Primidone; Seizures; Time Factors | 1979 |
Relapsing neuropathy, cerebral atrophy and folate deficiency. A close association.
Topics: Atrophy; Brain Diseases; Edema; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Intestinal Diseases; Jejunum; Middle Aged; Paralysis; Phenobarbital; Primidone; Radial Nerve; Restless Legs Syndrome; Syndrome | 1979 |
Monitoring saliva anticonvulsant levels in children.
Topics: Anticonvulsants; Carbamazepine; Child; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Saliva | 1979 |
Pharmacokinetics of primidone and its active metabolites in the dog.
Topics: Animals; Anticonvulsants; Dogs; Female; Half-Life; Injections, Intravenous; Kinetics; Male; Phenobarbital; Primidone | 1979 |
Intoxication with primidone: continuous monitoring of serum primidone and its metabolites during forced diuresis.
Topics: Adolescent; Diuresis; Female; Humans; Phenobarbital; Phenylethylmalonamide; Primidone | 1977 |
Simultaneous gas chromatographic analysis for the seven commonly used antiepileptic drugs in serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Succinimides | 1977 |
Therapeutic monitoring of anticonvulsant drugs in psychiatric patients: rapid, simultaneous gas-chromatographic determination of six commonly used anticonvulsants without interference from other drugs.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Succinimides | 1978 |
[A study on anticonvulsant level in body fluid. Ist report: serum level and drug interaction (author's transl)].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1977 |
A practical routine gas chromatographic determination of phenobarbital, primidone and diphenylhydantoin.
Topics: Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Spectrophotometry, Ultraviolet | 1978 |
The toxicity of the major anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1978 |
Hypocalcaemia and secondary hyperparathyroidism in institutionalised mentally-retarded patients receiving anticonvulsant drugs: a survey of 292 patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Child, Preschool; Female; Humans; Hydroxycholecalciferols; Hyperparathyroidism, Secondary; Hypocalcemia; Intellectual Disability; Male; Middle Aged; Osteomalacia; Osteoporosis; Parathyroid Hormone; Phenobarbital; Phenytoin; Primidone; Radiography | 1978 |
[A study on anticonvulsant level in body fluids. 2nd report: Dialyzed serum (free form), CSF and saliva level (author's transl)].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone; Saliva | 1978 |
Rapid quantitative method for the simultaneous determination of carbamazepine, carbamazepine-10,11-epoxide, diphenylhydantion, mephenytoin, phenobarbital and primidone in serum by thin-layer chromatography.
Topics: Carbamazepine; Chromatography, Thin Layer; Drug Combinations; Epoxy Compounds; Humans; Hydantoins; Mephenytoin; Phenobarbital; Phenytoin; Primidone | 1978 |
Simultaneous gas chromatographic determination of diphenylhydantoin, carbamazepin (Tegretol), phenobarbital and primidone in presence of Kemadrin (procyclidine) and Prolixin (fluphenazine) in plasma of psychiatric patients.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Fluphenazine; Humans; Mental Disorders; Methods; Phenobarbital; Phenytoin; Primidone; Procyclidine; Pyrrolidines | 1978 |
[Ratio of primidone to phenobarbital serum levels as a criterion in the assessment of anticonvulsive therapy with primidone (author's transl)].
Topics: Adolescent; Ambulatory Care; Child; Child, Preschool; Epilepsy; Humans; Phenobarbital; Primidone | 1978 |
Simultaneous determination of diphenylhydantoin, mephobarbital, carbamazepine, phenobarbital and primidone in serum using direct chemical ionization mass spectrometry.
Topics: Anticonvulsants; Carbamazepine; Computers; Evaluation Studies as Topic; Humans; Mass Spectrometry; Mephobarbital; Methods; Palmitic Acids; Phenobarbital; Phenytoin; Primidone | 1978 |
Epileptiform seizures in domestic fowl. VIII. Anticonvulsant activity of primidone and its metabolites, phenobarbital and phenylethylmalonamide.
Topics: Animals; Anticonvulsants; Chickens; Dimethyl Sulfoxide; Female; Male; Malonates; Phenobarbital; Phenylethylmalonamide; Primidone; Proadifen; Time Factors | 1978 |
Improved gas-chromatographic analysis for anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Reference Standards | 1978 |
Kinetics of drug interactions in the treatment of epilepsy.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Ethanol; Female; Humans; Kinetics; Male; Phenobarbital; Phenytoin; Pregnancy; Primidone; Salicylates | 1978 |
Rapid micro-method for the measurement of phenobarbitone, primidone and phenytoin in blood plasma or serum by gas-liquid chromatography.
Topics: Animals; Cattle; Chromatography, Gas; Chromatography, Liquid; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone; Time Factors | 1978 |
Brain concentrations of carbamazepine and carbamazepine-10,11-epoxide in epileptic patients.
Topics: Adolescent; Brain; Carbamazepine; Child; Epilepsy; Epoxy Compounds; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1978 |
Carbamazepine levels in pregnancy and lactation.
Topics: Adult; Carbamazepine; Epilepsy, Temporal Lobe; Female; Fetal Blood; Fetus; Humans; Lactation; Milk, Human; Phenobarbital; Pregnancy; Pregnancy Complications; Primidone | 1979 |
[Simultaneous determination of antiepileptic drugs in clinical laboratories: Problems of quality control and standardization (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Evaluation Studies as Topic; Humans; Methods; Phenobarbital; Phenytoin; Primidone; Quality Control | 1979 |
[Measurement of the blood concentration of antiepileptic drugs. II Special cases].
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1975 |
Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy.
Topics: Acetazolamide; Adolescent; Age Factors; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Male; Phenobarbital; Phenylacetates; Phenytoin; Primidone; Probenecid | 1975 |
Blood level estimation in phenytoin treatment of epilepsy.
Topics: Adult; Child; Chromatography, Gas; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Primidone | 1975 |
Seizures in adolescents.
Topics: Adolescent; Anticonvulsants; Automobile Driving; Benzodiazepines; Carbamazepine; Diagnosis, Differential; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Ethosuximide; Female; Humans; Hysteria; Male; Phenobarbital; Phenytoin; Physical Exertion; Pregnancy; Primidone; Psychology, Adolescent | 1975 |
Isoniazid as an inhibitor of primidone metabolism.
Topics: Depression, Chemical; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Isoniazid; Middle Aged; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Pyridoxine; Tuberculosis, Miliary | 1975 |
Sensible prescribing. XI.--Juvenile and adult epilepsy.
Topics: Adolescent; Adult; Age Factors; Carbamazepine; Child; Clonazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1975 |
Effects of different dosages of anticonvulsant drugs on mental performance in patients with chronic epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Child; Chronic Disease; Dose-Response Relationship, Drug; Epilepsies, Partial; Epilepsy; Humans; Intelligence Tests; Memory; Middle Aged; Phenobarbital; Phenytoin; Primidone; Reaction Time | 1975 |
Epilepsy: a controllable disease. Part 2. Drug therapy and nursing care.
Topics: Acute Disease; Adolescent; Anticonvulsants; Child; Epilepsy; Ethosuximide; Gingival Hyperplasia; Humans; Long-Term Care; Phenobarbital; Phenytoin; Primidone | 1976 |
Congenital malformations in four siblings of a mother taking anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anticonvulsants; Child; Child, Preschool; Epilepsy, Tonic-Clonic; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Pregnancy; Primidone; Trimethadione | 1976 |
[Epileptic seizures with psychomotor symptoms and generalized spike-wave-pattern].
Topics: Adolescent; Adult; Carbamazepine; Child; Diagnosis, Differential; Drug Therapy, Combination; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Female; Humans; Male; Phenobarbital; Primidone; Psychomotor Disorders; Succinimides | 1976 |
Epilepsy and other seizure disorders in children: drug management.
Topics: Acetazolamide; Anticonvulsants; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Primidone; Succinimides; Trimethadione | 1976 |
Simultaneous determination of phenobarbitone, primidone and phenytoin in small samples of blood by gas-liquid chromatography.
Topics: Chromatography, Gas; Chromatography, Liquid; Humans; Methods; Phenobarbital; Phenytoin; Primidone | 1977 |
Acetazolamide-induced interference with primidone absorption. Case reports and metabolic studies.
Topics: Acetazolamide; Adolescent; Adult; Female; Humans; Intestinal Absorption; Phenobarbital; Phenylethylmalonamide; Primidone; Time Factors | 1977 |
Micro-scale anticonvulsant assay with use of nitrogen/phosphorus detector and on-column methylation compared with a macro-scale procedure involving flame-ionization detection.
Topics: Anticonvulsants; Chromatography, Gas; Flame Ionization; Humans; Methylation; Phenobarbital; Phenytoin; Primidone | 1977 |
Rickets in children receiving anticonvulsant drugs. Biochemical and hormonal markers.
Topics: Adolescent; Anticonvulsants; Calcium; Child; Child, Preschool; Drug Combinations; Epilepsy; Evaluation Studies as Topic; Female; Humans; Male; Mephenytoin; Phenobarbital; Primidone; Rickets; United States; Vitamin D | 1977 |
Quality control in the simultaneous assay of anticonvulsants using an automated gas chromatographic system with a nitrogen detector.
Topics: Anticonvulsants; Chromatography, Gas; Humans; Methylation; Nitrogen; Phenobarbital; Phenytoin; Primidone; Quality Control | 1977 |
Simultaneous determination of anticonvulsant drugs by gas-liquid chromatography.
Topics: Anticonvulsants; Chromatography, Gas; Ethosuximide; Humans; Methods; Phenobarbital; Phenytoin; Primidone | 1977 |
Serum levels of anticonvulsants and haematological sequelae in black epileptics.
Topics: Adolescent; Adult; Aged; Black People; Child; Child, Preschool; Drug Combinations; Epilepsy; Erythrocytes; Female; Folic Acid; Humans; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1977 |
Evidence of osteomalacia in an outpatient group of adult epileptics.
Topics: Adult; Aged; Diet; Epilepsy; Female; Humans; Male; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Primidone; Time Factors | 1977 |
Evaluation of a rapid gas-chromatographic method for the simultaneous quantitative determination of ethosuximide, phenyletheylmalonediamide, carbamazepine, phenobarbital, primidone and diphenylhydantoin in human serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Evaluation Studies as Topic; Humans; Methods; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1977 |
Gas chromatographic on-column methylation technique for the simulataneous determination of antiepileptic drugs in blood.
Topics: Anticonvulsants; Chromatography, Gas; Ethosuximide; Methylation; Phenobarbital; Phenytoin; Primidone | 1977 |
[Determination of the blood levels of phenobarbital, primidone and diphenylhydantoin].
Topics: Chromatography, Gas; Humans; Methods; Phenobarbital; Phenytoin; Primidone; Radioimmunoassay | 1977 |
A comparison of the teratogenic activity of the antiepileptic drugs carbamazepine, clonazepam, ethosuximide, phenobarbital, phenytoin, and primidone in mice.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Female; Fetus; Lethal Dose 50; Maternal-Fetal Exchange; Mice; Phenobarbital; Phenytoin; Pregnancy; Primidone; Teratogens | 1977 |
The effect of anticonvulsant drugs which induce liver microsomal enzymes on derived and ingested phenobarbitone levels.
Topics: Adolescent; Adult; Biotransformation; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Microsomes, Liver; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1977 |
Kinetics of primidone metabolism and excretion in children.
Topics: Adolescent; Child; Female; Half-Life; Humans; Kinetics; Male; Phenobarbital; Primidone | 1977 |
The investigation of phenobarbitone, phenytoin and primidone in the death of epileptics.
Topics: Epilepsy; Forensic Medicine; Humans; Phenobarbital; Phenytoin; Primidone | 1977 |
[The anti-epileptic drugs].
Topics: Age Factors; Anticonvulsants; Carbamazepine; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1977 |
N-Acetyltryptophan ethyl ester: a new internal standard for the gas chromatographic determination of plasma anticonvulsant levels.
Topics: Anticonvulsants; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Tryptophan | 1977 |
Seizures in childhood encephalopathy or epilepsy?
Topics: Adolescent; Child; Epilepsy; Humans; Metabolic Diseases; Neurologic Examination; Phenobarbital; Primidone; Seizures; Seizures, Febrile | 1977 |
Distribution of plasma phenobarbital, diphenylhydantoin and primidone levels in epileptic patients.
Topics: Adult; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1977 |
The metabolism of primidone in non-pregnant and 14-day pregnant mice.
Topics: Animals; Female; Mice; Phenobarbital; Phenylethylmalonamide; Pregnancy; Pregnancy, Animal; Primidone; Teratogens | 1977 |
Plasma level studies of primidone and its metabolites in the mouse at various stages of pregnancy.
Topics: Animals; Female; Gestational Age; Malonates; Metabolic Clearance Rate; Mice; Phenobarbital; Phenylethylmalonamide; Pregnancy; Pregnancy, Animal; Primidone; Teratogens | 1977 |
Factors influencing plasma phenobarbitone levels in epileptic patients.
Topics: Adolescent; Adult; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Mephobarbital; Middle Aged; Phenobarbital; Primidone; Sex Factors | 1977 |
Multiple vitamin deficiencies in association with chronic anticonvulsant therapy.
Topics: Anticonvulsants; Ascorbic Acid Deficiency; Avitaminosis; Beriberi; Child, Preschool; Female; Heart Diseases; Humans; Phenobarbital; Phenytoin; Primidone; Rickets | 1977 |
Comparison of six procedures for the simultaneous determination of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone | 1977 |
Simultaneous high-pressure liquid-chromatographic determination of some anticonvulsants in serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Succinimides | 1976 |
Monitoring drug concentrations in a case of combined overdosage with primidone and methsuximide.
Topics: Adult; Computers; Female; Gas Chromatography-Mass Spectrometry; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone; Succinimides | 1976 |
Cerebrospinal fluid and plasma glutamine elevation by anticonvulsant drugs: a potential diagnostic and therapeutic trap.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Arginine; Child; Child, Preschool; Citrulline; Epilepsy; False Positive Reactions; Female; Glutamine; Humans; Infant; Male; Middle Aged; Ornithine; Phenobarbital; Primidone; Urea | 1976 |
Teratogenic effect of anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Acetazolamide; Anticonvulsants; Child; Child, Preschool; Diazepam; Female; Humans; Infant; Male; Pedigree; Phenobarbital; Phenytoin; Pregnancy; Primidone | 1976 |
Synthesis and characterization of alpha-phenyl-gamma-butyrolactone, a metabolite of glutethimide, phenobarbital and primidone, in human urine.
Topics: Glutethimide; Humans; Phenobarbital; Primidone | 1976 |
Ascorbic acid concentrations in human plasma and cerebrospinal fluid [proceedings].
Topics: Ascorbic Acid; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone | 1976 |
Simultaneous quantitative gas-chromatographic analysis of ethosuximide, phenobarbitone, primidone and diphenylhydantoin.
Topics: Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1976 |
An improved UV-spectrophotometric method for routine barbiturate monitoring.
Topics: Humans; Mephobarbital; Phenobarbital; Primidone; Spectrophotometry, Ultraviolet | 1976 |
Quantitative determination of underivatized anti-convulsant drugs by high resolution gas chromatography with support-coated open tubular columns.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone | 1976 |
Improved method for measurement of serum levels of phenobarbital, carbamazepine, primidone and diphenylhydantoin by gas-liquid chromatography.
Topics: Analysis of Variance; Carbamazepine; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Temperature | 1976 |
Simultaneous gas chromatographic analysis for the four commonly used antiepileptic drugs in serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ion Exchange Resins; Phenobarbital; Phenytoin; Primidone; Temperature | 1976 |
Anticonvulsant-induced dyskinesias: a comparison with dyskinesias induced by neuroleptics.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Cerebellar Diseases; Chorea; Dyskinesia, Drug-Induced; Extremities; Facial Muscles; Female; Humans; Male; Middle Aged; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Primidone; Syndrome; Tranquilizing Agents; Tremor | 1976 |
The necessity of drug level monitoring in anticonvulsant drug therapy.
Topics: Body Weight; Dose-Response Relationship, Drug; Epilepsy; Humans; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1976 |
Teratogenic activity of the antiepileptic drugs phenobarbital, phenytoin, and primidone in mice.
Topics: Animals; Cleft Palate; Drug Interactions; Female; Gestational Age; Leucovorin; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Pregnancy; Primidone; Teratogens | 1975 |
Letter: Sodium valproate in the treatment of intractable childhood epilepsy.
Topics: Diazepam; Drug Therapy, Combination; Epilepsy; Phenobarbital; Phenytoin; Primidone; Pyridoxine; Valerates; Valproic Acid | 1975 |
Surgery of temporal lobe epilepsy.
Topics: Adolescent; Adult; Astrocytes; Brain Neoplasms; Cerebral Cortex; Child; Child, Preschool; Electroencephalography; Epilepsy, Temporal Lobe; Follow-Up Studies; Glioma; Hemiplegia; Humans; Infant; Intellectual Disability; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Socioeconomic Factors; Temporal Lobe | 1975 |
Flash-heater ethylation of some antiepileptic drugs.
Topics: Alkylation; Anticonvulsants; Evaluation Studies as Topic; Hot Temperature; Humans; Mephenytoin; Mephobarbital; Methylation; Phenobarbital; Phenytoin; Primidone; Saliva | 1975 |
[Investigations of serum levels of drugs in children receiving anticonvulsant medication. I. General evaluation of serum concentrations of diphenylhydantoin, primidone and phenobarbitone (author's transl)].
Topics: Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Chromatography, Gas; Drug Therapy, Combination; Humans; Infant; Phenobarbital; Phenytoin; Primidone | 1975 |
[Investigations of serum levels of drugs in children receiving anticonvulsant medication. II. Clinical observations (author's transl)].
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Diazepam; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1975 |
Proceedings: Clinical pharmacokinetics of antiepileptic drugs. Quantitative variables of drug clearance used for the individual assessment of dosage regimens.
Topics: Anticonvulsants; Drug Interactions; Ethosuximide; Humans; Hydroxybutyrates; Phenobarbital; Phenytoin; Primidone | 1974 |
Improved method for the simultaneous determination of phenobarbital, primidone and diphenylhydantoin in patient's serum by gas-liquid chromatography.
Topics: Anticonvulsants; Chromatography, Gas; Drug Stability; Humans; Methods; Methylation; Phenobarbital; Phenytoin; Primidone | 1975 |
Anticonvulsant level in saliva, serum, and cerebrospinal fluid.
Topics: Carbamazepine; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Saliva | 1975 |
Study of the hepatic metabolism of primidone by improved methodology.
Topics: Animals; Bile; Carbon Radioisotopes; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Liver; Male; Perfusion; Phenobarbital; Phenylethylmalonamide; Primidone; Radiometry; Rats; Spectrophotometry, Ultraviolet; Time Factors | 1975 |
Effects and complications of high efficiency dialysis.
Topics: Barbiturates; Blood Urea Nitrogen; Body Weight; Calcium; Creatinine; Edema; Headache; Humans; Hypotension; Kidneys, Artificial; Nausea; Phenobarbital; Phenytoin; Poisoning; Primidone; Renal Dialysis; Salicylates; Substance-Related Disorders; Ultrafiltration; Uremia; Uric Acid | 1975 |
Letter: Gas-chromatography of anticonvulsant drugs, with no solvent evaporation.
Topics: Anticonvulsants; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone | 1975 |
Synthesis of millimole amounts of 14C- and 2D-labelled primidone, phenylethylmalonamide and phenobarbital for high-sensitivity detection in biological materials.
Topics: Biodegradation, Environmental; Body Fluids; Carbon Radioisotopes; Chromatography, Thin Layer; Countercurrent Distribution; Deuterium; Humans; Isotope Labeling; Malonates; Mass Spectrometry; Microchemistry; Phenobarbital; Phenylethylmalonamide; Primidone | 1975 |
Drug interaction: diazoxide and diphenylhydantoin.
Topics: Administration, Oral; Adolescent; Child, Preschool; Chromatography, Gas; Diazoxide; Drug Therapy, Combination; Ethosuximide; Humans; Hyperinsulinism; Hypoglycemia; Infant; Injections, Intramuscular; Male; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Radioligand Assay; Seizures | 1975 |
Cognitive and motor-sensory performances in toxic and nontoxic epileptic subjects.
Topics: Adult; Attention; Cognition; Epilepsy; Female; Humans; Intelligence Tests; Male; Motor Skills; Phenobarbital; Phenytoin; Primidone; Psychological Tests; Sensation | 1975 |
Congenital malformations due to anticonvulsive drugs.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Anencephaly; Anticonvulsants; Birth Order; Cleft Lip; Cleft Palate; Epilepsy; Female; Fetal Death; Folic Acid; Folic Acid Antagonists; Hemorrhage; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Trimethadione | 1975 |
Efficacy of standard anticonvulsants in monkey model with spontaneous motor seizures.
Topics: Aluminum; Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; Feeding Behavior; Humans; Macaca; Male; Motor Cortex; Phenobarbital; Phenytoin; Primidone; Reaction Time; Seizures; Substance Withdrawal Syndrome | 1975 |
[Polarographic determination of some phenylsubstituted anticonvulsants].
Topics: Anticonvulsants; Chromatography, Thin Layer; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Polarography; Primidone | 1975 |
[Nitration products of some phenyl-substituted anticonvulsants].
Topics: Anticonvulsants; Mephenytoin; Nitrogen; Phenobarbital; Phenytoin; Primidone | 1975 |
Folate and monoamine metabolism in epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Biogenic Amines; Epilepsy; Erythrocytes; Folic Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Middle Aged; Phenobarbital; Phenytoin; Primidone; Vitamin B 12 | 1975 |
Epilepsy anticonvulsants and malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Cleft Lip; Cleft Palate; Epilepsy; Female; Heart Defects, Congenital; Humans; Mephobarbital; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Teratogens | 1975 |
Acute primidone overdosage with massive crystalluria.
Topics: Child; Chromatography, Gas; Crystallization; Epilepsy, Temporal Lobe; Female; Humans; Phenobarbital; Phenytoin; Primidone; Time Factors | 1975 |
Diphenylhydantoin, phenobarbital, and primidone in saliva, plasma, and cerebrospinal fluid.
Topics: Humans; Kinetics; Phenobarbital; Phenytoin; Primidone; Saliva | 1975 |
Brain concentrations of phenytoin, phenobarbitone and primidone in epileptic patients.
Topics: Adolescent; Adult; Brain Chemistry; Child; Child, Preschool; Chromatography, Gas; Epilepsy, Temporal Lobe; Humans; Phenobarbital; Phenytoin; Primidone | 1975 |
Plasma level studies on different brands of sodium diphenylhydantoin (DPH) and primidone.
Topics: Biological Availability; Capsules; Epilepsy; Female; Humans; Kinetics; Male; Phenobarbital; Phenytoin; Primidone; Solubility; Tablets; Therapeutic Equivalency | 1975 |
Correlation of the "EMIT" antiepileptic drug assay with a gas liquid chromatographic method.
Topics: Autoanalysis; Chromatography, Gas; Humans; Immunoassay; Phenobarbital; Phenytoin; Primidone | 1976 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Trimethadione | 1976 |
Interlaboratory variability in determination of plasma antiepileptic drug concentrations.
Topics: Anticonvulsants; Epilepsy; Ethosuximide; Humans; Laboratories; Phenobarbital; Phenytoin; Primidone; Quality Control; United States | 1976 |
Simultaneous gas-chromatographic analysis for phenobarbital, diphenylhydantoin, carbamazepine, and primidone in serum.
Topics: Carbamazepine; Chromatography, Gas; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone; Time Factors | 1976 |
Simultaneous measurement of phenobarbital, diphenylhydantoin, and primidone in blood by high-pressure liquid chromatography.
Topics: Chromatography, Gas; Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Humans; Phenobarbital; Phenytoin; Primidone | 1976 |
Rapid micromethod for measuring anticonvulsant drugs in serum by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Ethosuximide; Evaluation Studies as Topic; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone | 1976 |
Rapid gas-chromatographic measurement of anticonvulsant drugs in serum.
Topics: Anticonvulsants; Chromatography, Gas; Evaluation Studies as Topic; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone; Time Factors | 1976 |
Ultramicro gas-chromatographic analysis for anticonvulsants, with use of a nitrogen-selective detector.
Topics: Chromatography, Gas; Humans; Microchemistry; Nitrogen; Phenobarbital; Phenytoin; Primidone | 1976 |
Single-dose kinetics of primidone in human subjects: effect of phenytoin on formation and elimination of active metabolites of primidone, phenobarbital and phenylethylmalonamide.
Topics: Adult; Biotransformation; Half-Life; Humans; Male; Middle Aged; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1992 |
Urinary metabolites of phenobarbitone, primidone, and their N-methyl and N-ethyl derivatives in humans.
Topics: Adult; Alkylation; Humans; Hydroxylation; Male; Phenobarbital; Primidone; Prospective Studies | 1992 |
Antiepileptics and the development of congenital anomalies.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Apgar Score; Birth Weight; Carbamazepine; Epilepsy; Female; Fetus; Gestational Age; Head; Humans; Hydantoins; Infant; Infant, Newborn; Phenobarbital; Pregnancy; Pregnancy Complications; Primidone; Syndrome; Valproic Acid | 1992 |
Performance of fluorescence polarisation immunoassay reagents for carbamazepine, phenytoin, phenobarbitone, primidone, and valproic acid on a Cobas Fara II analyser.
Topics: Anticonvulsants; Carbamazepine; Evaluation Studies as Topic; Fluorescence Polarization Immunoassay; Humans; Phenobarbital; Phenytoin; Primidone; Reference Standards; Valproic Acid | 1991 |
[Effectiveness of bromide in therapy resistant epilepsy of dogs].
Topics: Animals; Bromides; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Drug Resistance; Epilepsy; Epilepsy, Tonic-Clonic; Female; Male; Phenobarbital; Potassium; Potassium Compounds; Primidone | 1991 |
Simultaneous determination of six antiepileptic drugs by capillary gas chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Hydroxides; Phenobarbital; Phenytoin; Potassium; Potassium Compounds; Primidone; Valproic Acid | 1990 |
Determination of anticonvulsant drugs and methyl xanthine derivatives in serum by liquid chromatography with direct injection: column-switching method using a new internal-surface reversed-phase silica support as a precolumn.
Topics: Anticonvulsants; Caffeine; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Phenobarbital; Phenytoin; Primidone; Silicon Dioxide; Spectrophotometry, Ultraviolet; Theobromine; Theophylline; Xanthines | 1990 |
Development of monoclonal antibodies for therapeutic drug monitoring.
Topics: Antibodies, Monoclonal; Anticonvulsants; Carbamazepine; Cross Reactions; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1990 |
The disposition of primidone in elderly patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Biotransformation; Chromatography, High Pressure Liquid; Epilepsy; Female; Half-Life; Humans; Male; Phenobarbital; Phenylethylmalonamide; Primidone; Tremor | 1990 |
Primidone in the long-term treatment of essential tremor: a prospective study with computerized quantitative analysis.
Topics: Aged; Anxiety; Computers; Female; Humans; Male; Middle Aged; Phenobarbital; Primidone; Prospective Studies; Tremor | 1990 |
Metabolic studies with phenobarbitone, primidone and their N-alkyl derivatives: quantification of substrates and metabolites using chemical ionization gas chromatography-mass spectrometry.
Topics: Administration, Oral; Gas Chromatography-Mass Spectrometry; Humans; Male; Phenobarbital; Primidone | 1990 |
Clearance of phenylethylmalonamide during haemodialysis of a patient with renal failure.
Topics: Humans; Kidney Failure, Chronic; Male; Malonates; Middle Aged; Phenobarbital; Phenylethylmalonamide; Primidone; Renal Dialysis; Time Factors | 1990 |
The effect of concurrent administration of sodium valproate on serum levels of primidone and its metabolite phenobarbital.
Topics: Adolescent; Adult; Child; Child, Preschool; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Middle Aged; Phenobarbital; Primidone; Retrospective Studies; Valproic Acid | 1989 |
[Factors influencing the effectiveness of preventive treatment of febrile convulsions].
Topics: Anticonvulsants; Child; Drug Evaluation; Epilepsy; Female; Fever; Humans; Male; Phenobarbital; Primidone; Recurrence; Seizures; Spain; Valproic Acid | 1989 |
Acute primidone intoxication: report of a case.
Topics: Adult; Central Nervous System; Drug Overdose; Electroencephalography; Humans; Male; Phenobarbital; Primidone | 1989 |
Barbiturate-related connective tissue disorders.
Topics: Adult; Aged; Anticonvulsants; Barbiturates; Carbamazepine; Connective Tissue Diseases; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Prospective Studies | 1989 |
Comparison of the anticonvulsant efficacy of primidone and phenobarbital during chronic treatment of amygdala-kindled rats.
Topics: Amygdala; Animals; Anticonvulsants; Behavior, Animal; Electrodes, Implanted; Female; Kindling, Neurologic; Phenobarbital; Primidone; Rats; Rats, Inbred Strains; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders | 1989 |
Saliva monitoring of anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Saliva | 1989 |
Value of saliva anticonvulsant monitoring in pregnancy and the newborn.
Topics: Anticonvulsants; Carbamazepine; Female; Humans; Infant, Newborn; Monitoring, Physiologic; Phenobarbital; Phenytoin; Pregnancy; Primidone; Saliva | 1989 |
Primidone/phenobarbital-induced periodic alternating nystagmus.
Topics: Adult; Electronystagmography; Eye Movements; Humans; Male; Nystagmus, Pathologic; Periodicity; Phenobarbital; Primidone; Visual Acuity | 1989 |
Rapid and sensitive determination of ethotoin as well as carbamazepine, phenobarbital, phenytoin and primidone in human serum.
Topics: Carbamazepine; Gas Chromatography-Mass Spectrometry; Humans; Hydantoins; Kinetics; Phenobarbital; Phenytoin; Powders; Primidone; Tablets | 1986 |
Factors that affect the induction of gamma glutamyltransferase in epileptic patients receiving anti-convulsant drugs.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Induction; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Infant; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Sex Factors | 1987 |
Nursing interventions for anticonvulsant drug interactions.
Topics: Anticonvulsants; Biotransformation; Carbamazepine; Drug Interactions; Humans; Nursing Care; Patient Education as Topic; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1986 |
Low levels of gamma-aminobutyric acid in cerebrospinal fluid of dogs with epilepsy.
Topics: Animals; Dogs; Epilepsy, Tonic-Clonic; Female; gamma-Aminobutyric Acid; Male; Phenobarbital; Primidone | 1986 |
Carbamazepine, phenytoin and phenobarbital in drug-resistant partial epilepsies.
Topics: Adolescent; Adult; Carbamazepine; Drug Evaluation; Drug Resistance; Epilepsies, Partial; Epilepsy, Temporal Lobe; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1986 |
Use of anticonvulsants in small animals.
Topics: Animals; Anticonvulsants; Cat Diseases; Cats; Dog Diseases; Dogs; Epilepsy; Epilepsy, Tonic-Clonic; Phenobarbital; Primidone | 1986 |
Phenylethylmalonamide serum levels in patients treated with primidone and the effects of other antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Malonates; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Valproic Acid | 1986 |
Pharmacologic interactions between valproate and other drugs.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1988 |
Withdrawal of barbiturate anticonvulsant drugs: prospective controlled study.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenobarbital; Primidone; Substance Withdrawal Syndrome | 1988 |
[Prognosis of complicated febrile convulsions in therapy with primidone, cathine-phenobarbital and calcium valproinate].
Topics: Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Male; Phenobarbital; Phenylpropanolamine; Primidone; Prognosis; Seizures, Febrile; Valproic Acid | 1988 |
Chronic primidone treatment in the rat: an animal model of primidone therapy.
Topics: Administration, Oral; Animals; Male; Models, Biological; Phenobarbital; Primidone; Rats; Rats, Inbred Strains; Seizures; Time Factors; Tissue Distribution | 1988 |
[Serum levels of triiodothyronine, thyroxine and thyrotropin in children with epilepsy treated with amizepine, luminal and mizodine in a monotherapy system. Preliminary report].
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Male; Phenobarbital; Primidone; Thyrotropin; Thyroxine; Triiodothyronine | 1988 |
Primidone and essential tremor.
Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Phenobarbital; Phenylethylmalonamide; Primidone; Tremor | 1988 |
Effectiveness of a therapeutic drug monitoring service as an aid to the control of canine seizures.
Topics: Animals; Dog Diseases; Dogs; Epilepsy; Female; Male; Phenobarbital; Primidone | 1988 |
Primidone and phenobarbital during lactation period in epileptic women: total and free drug serum levels in the nursed infants and their effects on neonatal behavior.
Topics: Behavior; Epilepsy; Female; Half-Life; Humans; Infant, Newborn; Milk, Human; Phenobarbital; Primidone; Substance Withdrawal Syndrome | 1988 |
Seizures during barbiturate withdrawal: relation to blood level.
Topics: Humans; Phenobarbital; Primidone; Seizures; Substance Withdrawal Syndrome; Time Factors | 1987 |
[Cytogenetic analysis of lymphocytes from epileptic dogs].
Topics: Animals; Anticonvulsants; Chromosome Aberrations; Dog Diseases; Dogs; Epilepsy; Lymphocytes; Phenobarbital; Primidone; Sister Chromatid Exchange | 1987 |
Minor additive inducing effects of phenobarbital on carbamazepine clearance in patients on combined carbamazepine-phenytoin therapy.
Topics: Aged; Carbamazepine; Drug Interactions; Epilepsy; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1987 |
Essential tremor.
Topics: Diagnosis, Differential; Humans; Parkinson Disease; Phenobarbital; Phenylethylmalonamide; Primidone; Propranolol; Tremor | 1986 |
Effect of primidone in somatic and germ cells of mice.
Topics: Animals; Bone Marrow; Germ Cells; Male; Mice; Mutagens; Phenobarbital; Primidone; Sperm Head | 1986 |
Toxic hepatopathy and intrahepatic cholestasis associated with phenytoin administration in combination with other anticonvulsant drugs in three dogs.
Topics: Animals; Anticonvulsants; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Dog Diseases; Dogs; Liver Diseases; Male; Phenobarbital; Phenytoin; Primidone; Seizures | 1987 |
Dual-label fluoroimmunoassay for simultaneous determination of primidone and phenobarbital.
Topics: Fluorescent Antibody Technique; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Methods; Monitoring, Physiologic; Phenobarbital; Primidone; Rhodamines | 1985 |
Evaluation of an automated system (Optimate) for substrate-labeled fluorescent immunoassays.
Topics: Anti-Bacterial Agents; Carbamazepine; Evaluation Studies as Topic; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Indicators and Reagents; Methods; Phenobarbital; Phenytoin; Primidone; Quinidine; Theophylline | 1985 |
Effects of pregnancy on antiepileptic drug utilization.
Topics: Anticonvulsants; Biological Availability; Carbamazepine; Epilepsy; Female; Humans; Kinetics; Metabolic Clearance Rate; Patient Compliance; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Valproic Acid | 1985 |
Concurrent determination of valproic acid with other antiepileptic drugs by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1985 |
Monotherapy and polytherapy for intractable epilepsies.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1985 |
Alternative single anticonvulsant drug therapy for refractory epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Chronic Disease; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone | 1986 |
Carbamazepine and carbamazepine-10,11-epoxide serum concentrations in epileptic children.
Topics: Adolescent; Age Factors; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Infant; Kinetics; Male; Phenobarbital; Phenytoin; Primidone; Sex Factors | 1985 |
Therapeutic efficacy of phenobarbital and primidone in canine epilepsy: a comparison.
Topics: Animals; Dog Diseases; Dogs; Epilepsy; Phenobarbital; Primidone | 1985 |
Differential effect of anionic and cationic drugs on the synaptosome-associated acetylcholinesterase activity of dog brain.
Topics: Acetylcholinesterase; Animals; Antidepressive Agents; Barbiturates; Brain; Dogs; Imipramine; Perphenazine; Phenobarbital; Primidone; Synaptosomes; Trifluoperazine | 1985 |
Congenital malformations among infants born to epileptic women.
Topics: Abnormalities, Drug-Induced; Cleft Lip; Cleft Palate; Congenital Abnormalities; England; Epilepsy; Female; Humans; Infant, Newborn; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone | 1973 |
Coarse features in epilepsy as a consequence of anticonvulsant therapy. Report of cases in two pairs of identical twins.
Topics: Acromegaly; Adult; Anticonvulsants; Carbamazepine; Child; Diazepam; Diseases in Twins; Epilepsy; Epilepsy, Tonic-Clonic; Ethosuximide; Face; Female; Haloperidol; Humans; Hydantoins; Male; Phenobarbital; Phenytoin; Primidone; Thiazines | 1973 |
Are anticonvulsants oncogenic?
Topics: Anticonvulsants; Denmark; Epilepsy; Female; Humans; Male; Neoplasms; Phenobarbital; Phenytoin; Primidone; Sex Factors; Time Factors | 1974 |
[Calcium metabolism during antiepileptic therapy].
Topics: Adult; Alkaline Phosphatase; Anticonvulsants; Antipsychotic Agents; Calcium; Calcium Isotopes; Creatinine; Diazepam; Drug Combinations; Epilepsy; Ethosuximide; Female; Humans; Long-Term Care; Male; Phenobarbital; Phenothiazines; Phenytoin; Piperazines; Primidone; Time Factors | 1973 |
Specific H-bonding of glutarimides and hydantoins to derivatives of RNA bases in chloroform solution.
Topics: Bemegride; Chemical Phenomena; Chemistry; Chloroform; Cycloheximide; Ethosuximide; Glutethimide; Hydantoins; Pemoline; Phenobarbital; Phenytoin; Piperidines; Piperidones; Primidone; RNA; Spectrophotometry, Infrared; Thalidomide | 1973 |
Effect of clonazepam (Ro 5-4023) on epileptic seizures.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepinones; Carbamazepine; Chlorobenzenes; Drug Evaluation; Drug Therapy, Combination; Epilepsy; Fatigue; Female; Humans; Hydantoins; Male; Nitro Compounds; Phenobarbital; Primidone; Thiazines; Time Factors | 1973 |
Choreo-athetosis and encephalopathy induced by phenytoin.
Topics: Adolescent; Adult; Ataxia; Athetosis; Carbamazepine; Chorea; Diplopia; Electroencephalography; Epilepsy; Humans; Intelligence; Male; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Primidone; Thiazines | 1974 |
Prevalence and treatment of vitamin D deficiency in children on anticonvulsant drugs.
Topics: Adolescent; Alkaline Phosphatase; Anticonvulsants; Calcium; Cholecalciferol; Diet; Enzyme Induction; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Leucyl Aminopeptidase; Liver; Male; Nucleotidases; Phenobarbital; Phenytoin; Phosphates; Primidone; Radiography; Vitamin D Deficiency; Wrist | 1974 |
Assessment of plasma glutamyl transpeptidase activity and urinary D-glucaric acid excretion as indices of enzyme induction.
Topics: Adipates; Anticonvulsants; Child; Child, Preschool; Enzyme Induction; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Kinetics; Liver Function Tests; Male; Phenobarbital; Phenytoin; Primidone; Sugar Acids | 1974 |
Effect of barbiturates and isoniazid on cerebral hemisphere gamma-aminobutyric acid content in pp' DDT treated mice.
Topics: Aminobutyrates; Animals; Anticonvulsants; Barbiturates; Behavior, Animal; Brain Chemistry; DDT; Drug Synergism; gamma-Aminobutyric Acid; Isoniazid; Male; Mephobarbital; Mice; Phenobarbital; Primidone; Seizures | 1974 |
Epilepsy.
Topics: Adrenocorticotropic Hormone; Carbamazepine; Diazepam; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Epilepsy; Epilepsy, Absence; Epilepsy, Post-Traumatic; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant, Newborn; Liver; Nitrazepam; Phenobarbital; Phenytoin; Prednisolone; Primidone; Spasm; Syndrome; Thiazines | 1974 |
Gastrointestinal function in anticonvulsant megaloblastic anaemia.
Topics: Adult; Anemia, Macrocytic; Epilepsy; Female; Folic Acid; Humans; Intestinal Absorption; Phenobarbital; Phenytoin; Primidone; Vitamin B 12 | 1966 |
Effects of folic acid on the mental state and fit-frequency of drug-treated epileptic patients.
Topics: Adolescent; Adult; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Humans; Male; Mental Health; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1967 |
Neuropsychiatric aspects of anticonvulsant megaloblastic anaemia.
Topics: Acetazolamide; Adult; Anemia, Macrocytic; Epilepsy; Female; Folic Acid; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Psychophysiologic Disorders; Thiazines; Vitamin B 12 | 1968 |
Neonatal haemorrhage following maternal anticonvulsant therapy.
Topics: Adult; Anticonvulsants; Epilepsy; Female; Humans; Infant, Newborn; Male; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Vitamin K; Vitamin K Deficiency Bleeding | 1970 |
[Distinct rickets during anticonvulsant long-term therapy].
Topics: Child, Preschool; Enzyme Induction; Epilepsy, Tonic-Clonic; Female; Humans; Phenobarbital; Phenytoin; Primidone; Radiography; Rickets; Vitamin D | 1973 |
The effect of anticonvulsant therapy upon the absorption of folates.
Topics: Adult; Aged; Anticonvulsants; Biological Assay; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Intestinal Absorption; Lacticaseibacillus casei; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1973 |
[Inheritance of spike-wave complexes and febrile seizures in three generations].
Topics: Adult; Child; Child, Preschool; Electroencephalography; Epilepsy; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Fever; Genes, Dominant; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Time Factors | 1973 |
Antiepileptic therapy and rickets in children.
Topics: Adolescent; Anticonvulsants; Barbiturates; Child; Child, Preschool; Diazepam; Epilepsy; Epilepsy, Tonic-Clonic; Female; Humans; Infant; Male; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Rickets | 1973 |
The pattern of epilepsy in Uganda.
Topics: Adolescent; Adult; Age Factors; Black People; Child; Child, Preschool; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Folklore; Humans; Male; Phenobarbital; Phenytoin; Primidone; Sex Factors; Socioeconomic Factors; Time Factors; Uganda | 1973 |
Folate studies in underprivileged children with epilepsy.
Topics: Anticonvulsants; Biological Assay; Child; Child, Preschool; Epilepsy; Euglena; Folic Acid; Hematocrit; Hemoglobins; Humans; Lacticaseibacillus casei; Leukocyte Count; Phenobarbital; Phenytoin; Primidone; Vitamin B 12 | 1973 |
Psychomotor epilepsy in childhood.
Topics: Bromides; Carbamazepine; Child; Child, Preschool; Diagnosis, Differential; Electroencephalography; Epilepsy, Absence; Epilepsy, Temporal Lobe; Humans; Infant; Phenobarbital; Phenytoin; Primidone; Radiography; Recurrence; Skull; Time Factors | 1974 |
Bioavailability of primidone in epileptic patients.
Topics: Administration, Oral; Adult; Amides; Epilepsy; Humans; Long-Term Care; Male; Malonates; Middle Aged; Phenobarbital; Primidone; Time Factors | 1974 |
Therapy of seizures in children.
Topics: Child; Diazepam; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Injections, Intramuscular; Injections, Intravenous; Paraldehyde; Phenobarbital; Phenytoin; Primidone; Rectum; Seizures | 1974 |
Clinical and experimental studies on folic acid deficiency due to anticonvulsants. 2. Investigations on patients receiving anticonvulsants and experimental study on the effect of diphenylhydantoin on the absorption of folic acid in rats.
Topics: Adolescent; Adult; Animals; Anticonvulsants; Cell Nucleus; Depression, Chemical; Epithelial Cells; Female; Folic Acid; Folic Acid Deficiency; Humans; Intestinal Absorption; Intestine, Small; Iron; Kidney; Leukocyte Count; Liver; Male; Middle Aged; Mouth Mucosa; Neutrophils; Phenobarbital; Phenytoin; Primidone; Rats; Tritium; Vitamin B 12 | 1971 |
[Current criteria of medical therapy of epilepsy].
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Anticonvulsants; Child; Child, Preschool; Dexamethasone; Diazepam; Epilepsy; Ethosuximide; Humans; Hydantoins; Hypnotics and Sedatives; Infant; Phenobarbital; Primidone | 1967 |
Drug treatment of convulsive disorders.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Adult; Anticonvulsants; Barbiturates; Child; Diazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant; Myoclonus; Oxazoles; Phenobarbital; Phenytoin; Primidone; Pyrrolidinones; Seizures; Trimethadione | 1972 |
[Severe rachitic osteopathy during long-term anticonvulsant treatment].
Topics: Administration, Oral; Alkaline Phosphatase; Anticonvulsants; Biopsy; Calcium; Carbamazepine; Child; Cholecalciferol; Epilepsy, Tonic-Clonic; Humans; Ilium; Iron; Long-Term Care; Male; Osteomalacia; Phenobarbital; Phenytoin; Phosphorus; Primidone; Rickets | 1973 |
Peripheral nerve function in long-term therapy with diphenylhydantoin. A clinical and electrophysiologic correlation.
Topics: Adult; Aged; Carbamazepine; Electric Stimulation; Electromyography; Epilepsy; Ethosuximide; Evoked Potentials; Female; Folic Acid; Humans; Male; Median Nerve; Middle Aged; Neural Conduction; Peripheral Nerves; Peripheral Nervous System Diseases; Peroneal Nerve; Phenobarbital; Phenytoin; Primidone; Reaction Time; Reflex, Monosynaptic; Sural Nerve; Time Factors; Vitamin B 12 | 1974 |
Clinical experience with sulthiame (Ospolot).
Topics: Adolescent; Adult; Anticonvulsants; Brain Damage, Chronic; Epilepsy, Temporal Lobe; Female; Humans; Intellectual Disability; Male; Mental Disorders; Middle Aged; Phenobarbital; Phenytoin; Primidone; Thiazines | 1966 |
Motor convulsions and EEG during maximal electroshock in the rat.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Cornea; Electric Stimulation; Electroencephalography; Electroshock; Muscles; Phenobarbital; Phenytoin; Primidone; Rats; Seizures; Stress, Physiological; Succinimides; Thiazines; Trimethadione | 1967 |
The relation between primidone and phenobarbitone blood levels.
Topics: Chromatography, Gas; Chromatography, Thin Layer; Humans; Phenobarbital; Primidone | 1968 |
Increased susceptibility of mice to seizures after some anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Bemegride; Central Nervous System Stimulants; Drug Synergism; Electroshock; Ethionine; Female; Hydantoins; Male; Methods; Mice; Oxazines; Pentylenetetrazole; Phenobarbital; Phenytoin; Primidone; Rats; Seizures; Trimethadione | 1967 |
Epilepsy.
Topics: Adult; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Folic Acid Deficiency; Humans; Male; Phenobarbital; Phenytoin; Pregnancy; Primidone; Psychoses, Substance-Induced; Thiazines | 1969 |
Drug treatment of epilepsy in childhood.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant; Paraldehyde; Phenobarbital; Phenytoin; Primidone; Thiazines | 1969 |
The effect of isoniazid and some anticonvulsant drugs on the gamma-aminobutyric acid content of mouse brain in insulin hypoglycaemia.
Topics: Aminobutyrates; Animals; Barbiturates; Brain; Brain Chemistry; Cerebral Cortex; Hypoglycemia; Insulin Antagonists; Isoniazid; Male; Mephobarbital; Mice; Phenobarbital; Primidone; Seizures | 1970 |
[Comparative action of p-chlorbenzolsulfonamide with other anticonvulsants in audiogenic convulsions in rats].
Topics: Acetazolamide; Animals; Anticonvulsants; Hearing; Noise; Phenobarbital; Primidone; Rats; Seizures; Sulfonamides; Thiazines | 1969 |
Interference of barbiturates with pyrimidine incorporation. II. Structural specificity of the inhibition of orotate uptake in Bacillus cereus.
Topics: Amobarbital; Bacillus cereus; Barbiturates; Bemegride; Biological Transport; Carbon Isotopes; Carboxylic Acids; Central Nervous System Stimulants; Chemical Phenomena; Chemistry; Chemistry, Physical; Chlorine; Chlorpromazine; Glutethimide; Hexobarbital; Hydantoins; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; Orotic Acid; Pentobarbital; Phenobarbital; Phenytoin; Primidone; Solubility; Succinimides; Thiopental; Thymine; Trimethadione; Tromethamine; Uracil; Urea | 1970 |
Anticonvulsant drugs in idiopathic epilepsy.
Topics: Acetazolamide; Anticonvulsants; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Hydantoins; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Substance Withdrawal Syndrome; Succinimides; Urea | 1970 |
A comprehensive scheme for the evaluation of anticonvulsant concentrations in blood using thin-layer chromatography.
Topics: Acetazolamide; Anticonvulsants; Benzazepines; Carbamazepine; Chlordiazepoxide; Chromatography, Thin Layer; Diazepam; Epilepsy; Ethosuximide; Humans; Hydantoins; Mephobarbital; Nitro Compounds; Oxazepam; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines | 1971 |
Anticonvulsant drugs. I. Patho-physiological and pharmacological aspects.
Topics: Acetates; Acetazolamide; Anticonvulsants; Carbamazepine; Diazepam; Dibenzazepines; Electroencephalography; Epilepsies, Partial; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Succinimides; Thiazines; Trimethadione | 1972 |
The influence of anticonvulsant drugs on formyl tetrahydrofolic acid stimulation of rat brain respiration in vitro.
Topics: Animals; Anticonvulsants; Brain; Dose-Response Relationship, Drug; In Vitro Techniques; Leucovorin; Male; Microsomes; Norepinephrine; Oxygen Consumption; Phenobarbital; Phenytoin; Primidone; Rats; Scopolamine; Synaptosomes; Thiazines | 1972 |
[Micro-method for the quantitative determination of sedatives and antipyretics (aminophenazone, diphenylhydantoin, paracetamol, phenobarbital, primidone) using thermo-gas chromatography].
Topics: Acetaminophen; Aminopyrine; Analgesics; Chromatography, Gas; Hypnotics and Sedatives; Methods; Microchemistry; Phenobarbital; Phenytoin; Primidone; Temperature | 1974 |
An evaluation of a drug administration system in a psychiatric hospital.
Topics: Acetaminophen; Antidepressive Agents; Benzodiazepinones; Hospitals, Psychiatric; Humans; Medication Errors; Medication Systems, Hospital; Phenobarbital; Phenothiazines; Phenytoin; Primidone; Salicylates; Scotland | 1974 |
Letter: Primidone thrombocytopenia.
Topics: Adult; Female; Humans; Phenobarbital; Primidone; Seizures; Thrombocytopenia | 1974 |
Letter: Sleep epilepsy.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Delayed-Action Preparations; Dextroamphetamine; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Sleep Wake Disorders | 1974 |
Letter: Anticonvulsants and vitamin D metabolism.
Topics: Child; Drug Therapy, Combination; Epilepsy; Humans; Osteomalacia; Phenobarbital; Phenytoin; Primidone; Rickets | 1974 |
Serum immunoglobulins in epilepsy.
Topics: Adult; Drug Therapy, Combination; Epilepsy; Erythrocytes; Female; Folic Acid; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Male; Phenobarbital; Phenytoin; Primidone | 1974 |
Simultaneous determination of some antiepileptic drugs by gas-liquid chromatography.
Topics: Analysis of Variance; Carbamazepine; Chromatography, Gas; Colorimetry; Evaluation Studies as Topic; Humans; Phenobarbital; Phenytoin; Primidone; Spectrophotometry | 1974 |
Do anticonvulsants have a teratogenic effect?
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Child, Preschool; Cleft Lip; Cleft Palate; Congenital Abnormalities; Epilepsy; Female; Heart Defects, Congenital; Humans; Infant; Infant Mortality; Infant, Newborn; Intellectual Disability; Male; Mephobarbital; Minnesota; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Primidone; Teratogens | 1974 |
Broad-spectrum simultaneous GLC assay of nonderivatized antiepileptic drugs.
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Quality Control; Trimethadione | 1974 |
[Considerations and research on febrile convulsions].
Topics: Anticonvulsants; Brain Diseases; Child, Preschool; Diagnosis, Differential; Diazepam; Electroencephalography; Epilepsy; Female; Fever; Humans; Infant; Male; Mannitol; Phenobarbital; Phenytoin; Primidone; Seizures | 1974 |
[Special viewpoints in the treatment with anticonvulsants in childhood. Value of determination of serum level of anticonvulsants in the treatment of seizures].
Topics: Adolescent; Anticonvulsants; Child, Preschool; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1974 |
Iatrogenic nutritional effects of anticonvulsants.
Topics: Adolescent; Adult; Anticonvulsants; Blood Coagulation Disorders; Bone Diseases; Child; Child, Preschool; Connective Tissue; Endocrine Glands; Enzyme Induction; Epilepsy; Female; Folic Acid Deficiency; Humans; Iatrogenic Disease; Infant; Infant, Newborn; Liver; Nutrition Disorders; Phenobarbital; Phenytoin; Pregnancy; Primidone; Pyridoxine; Vitamin D Deficiency | 1974 |
Phenobarbital-induced coagulation defects in cats.
Topics: Alanine Transaminase; Animals; Animals, Newborn; Blood Coagulation; Blood Coagulation Disorders; Cats; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; Factor V Deficiency; Factor VII; Factor VII Deficiency; Female; Folic Acid; Hemophilia A; Hypoprothrombinemias; Liver; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Primidone; Rats; Vitamin K | 1974 |
Effects of age, sex, obesity, and pregnancy on plasma diphenylhydantoin levels.
Topics: Adolescent; Adult; Age Factors; Analysis of Variance; Chromatography, Gas; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Kinetics; Male; Middle Aged; Obesity; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Regression Analysis; Sex Factors; Spectrophotometry | 1974 |
Toxic epidermal necrolysis provoked by barbiturates.
Topics: Adrenal Cortex Hormones; Aged; Endocarditis; Female; Gastrointestinal Hemorrhage; Humans; Phenobarbital; Prednisolone; Primidone; Stevens-Johnson Syndrome; Trigeminal Neuralgia | 1973 |
A medical and social survey of 231 children with seizures.
Topics: Adolescent; Attitude to Health; Child; Child Behavior Disorders; Child, Preschool; Electroencephalography; Employment; Encephalitis; Epilepsy; Epilepsy, Absence; Ethosuximide; Female; Greece; Humans; Infant; Intelligence; Male; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Seizures; Socioeconomic Factors | 1972 |
Variation in response to anticonvulsants in a group of epileptic patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Chromatography, Gas; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Sex Factors | 1972 |
Phenylethylmalonamide (PEMA). An important metabolite of primidone.
Topics: Adult; Amides; Animals; Blood Proteins; Chromatography, Gas; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethers; Female; Half-Life; Humans; Male; Malonates; Phenobarbital; Primidone; Rats; Sleep | 1972 |
Megaloblastic anemia after anticonvulsive therapy.
Topics: Adult; Anemia, Macrocytic; Anticonvulsants; Epilepsies, Partial; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1972 |
Metabolic disposition of primidone and its metabolites in epileptic subjects after single and repeated administration.
Topics: Amides; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Primidone | 1972 |
Long term anticonvulsant therapy and cerebellar atrophy.
Topics: Adult; Avitaminosis; Cerebellar Diseases; Cranial Fossa, Posterior; Epilepsy, Tonic-Clonic; Female; Follow-Up Studies; Humans; Phenobarbital; Phenytoin; Pneumoencephalography; Primidone | 1973 |
Chemical analysis of massive crystalluria following primidone overdose.
Topics: Adult; Amides; Chromatography, Gas; Chromatography, Thin Layer; Crystallization; Female; Humans; Phenobarbital; Poisoning; Primidone; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Suicide | 1972 |
[Osteomalacia due to a long-term antiepileptic treatment].
Topics: Anticonvulsants; Calcium; Female; Humans; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Primidone; Time Factors; Vitamin D | 1972 |
[Chromosome studies on the effect of primidone (Mylepsinum) and its metabolites phenobarbital and phenylethylmalondiamide in vitro].
Topics: Amides; Cell Division; Cells, Cultured; Chromosome Aberrations; Chromosomes; Humans; In Vitro Techniques; Lymphocytes; Malonates; Mitosis; Phenobarbital; Polyploidy; Primidone; Probability | 1972 |
Clinical conference: megaloblastic anemia associated with anticonvulsant drugs.
Topics: Adult; Anemia, Macrocytic; Anticonvulsants; Female; Folic Acid; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone | 1972 |
Relationships between serum and cerebrospinal fluid anticonvulsant drug and folic acid concentrations in epileptic patients.
Topics: Adult; Chromatography, Gas; Epilepsy; Female; Folic Acid; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1972 |
The simultaneous determination of multiple anticonvulsant drug levels by gas-liquid chromatography. Method and clinical application.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Chromatography, Gas; Epilepsy; Ethosuximide; Female; Humans; Infant; Male; Methods; Methylphenidate; Phenobarbital; Phenytoin; Primidone | 1972 |
A gas-chromatographic method for the simultaneous determination of phenobarbitone, primidone and phenytoin in serum using a nitrogen detector.
Topics: Chromatography, Gas; Electrodes; Humans; Indicators and Reagents; Methods; Methylation; Nitrogen; Phenobarbital; Phenytoin; Primidone | 1973 |
Follow-up of epileptic outpatients.
Topics: Adolescent; Adult; Aged; Educational Status; Employment; Epilepsy; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Rehabilitation, Vocational; Surveys and Questionnaires | 1973 |
Leucine aminopeptidase isoenzyme changes after treatment with anticonvulsant drugs.
Topics: Blood Protein Electrophoresis; Blood Proteins; Epilepsy; Humans; Isoenzymes; Jaundice; Leucyl Aminopeptidase; Phenobarbital; Phenytoin; Primidone | 1973 |
Simultaneous determination of carbamazapine ("Tegretol") and other anticonvulsants in human plasma by gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Computers; Dibenzazepines; Humans; Hydantoins; Mephobarbital; Methods; Methylation; Microchemistry; Phenobarbital; Phenytoin; Primidone; Quaternary Ammonium Compounds | 1973 |
GC assay of phenobarbital.
Topics: Amides; Benzene Derivatives; Chromatography, Gas; Humans; Malonates; Phenobarbital; Phenytoin; Primidone; Quaternary Ammonium Compounds | 1973 |
Metabolism and anticonvulsant properties of primidone in the rat.
Topics: Amides; Animals; Anticonvulsants; Brain Chemistry; Chromatography, Gas; Electroshock; Male; Malonates; Pentylenetetrazole; Phenobarbital; Primidone; Rats; Seizures; Time Factors | 1973 |
Chronic and severe phenobarbital intoxication in a child treated with primidone and diphenylhydantoin.
Topics: Anticonvulsants; Biotransformation; Chromatography, Gas; Drug Interactions; Female; Humans; Infant; Infant, Newborn; Phenobarbital; Phenytoin; Primidone; Seizures | 1973 |
[Severe osteomalacic rickets induced by antiepileptic drugs. Literature review apropos of a case].
Topics: Child; Child, Preschool; Humans; Male; Osteomalacia; Phenobarbital; Phenytoin; Primidone; Rickets; Vitamin D | 1973 |
Vitamin D-dependent rickets in institutionalized, mentally retarded children receiving long-term anticonvulsant therapy. I. A survey of 288 patients.
Topics: Adolescent; Alkaline Phosphatase; Anticonvulsants; Calcium; Child; Child, Preschool; Female; Humans; Infant; Intellectual Disability; Magnesium; Male; Mephobarbital; Mesoridazine; Phenobarbital; Phenytoin; Phosphorus; Potassium; Primidone; Rickets; Seizures; Sodium; Succinimides; Vitamin D | 1973 |
Pheneturide, a more potent liver enzyme inducer in man than phenobarbitone?
Topics: Adipates; Anticonvulsants; Enzyme Induction; Epilepsy; Female; Humans; Liver; Male; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Sugar Acids; Urea | 1973 |
Primidone, diphenylhydantoin and phenobarbital. Aspects of acute and chronic toxicity.
Topics: Ataxia; Chromatography, Gas; Drug Tolerance; Epilepsy; Humans; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Primidone | 1973 |
Preliminary observations of serum carbamazepine concentration in epileptic patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1973 |
Transplacental passage of primidone.
Topics: Female; Fetus; Humans; Infant, Newborn; Infant, Newborn, Diseases; Labor, Obstetric; Maternal-Fetal Exchange; Phenobarbital; Pregnancy; Pregnancy Complications; Primidone; Seizures | 1973 |
The role of antiepileptic blood levels in the treatment of patients with epilepsy.
Topics: Adult; Drug Therapy, Combination; Epilepsy; Female; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1973 |
[Editorial: Antiepileptic agents--folic acid].
Topics: Anemia, Macrocytic; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone; Vitamin B 12 | 1973 |
Rapid, simultaneous GLC determination of phenobarbital, primidone, and diphenylhydantoin.
Topics: Chromatography, Gas; Methods; Phenobarbital; Phenytoin; Primidone; Time Factors | 1973 |
A rapid method for the estimation of anti-epileptic drugs in blood serum by gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Epilepsy; Ethosuximide; Evaluation Studies as Topic; Humans; Mephobarbital; Methods; Methylation; Microchemistry; Phenobarbital; Phenytoin; Primidone; Succinimides; Temperature; Time Factors; Trimethadione | 1973 |
The teratological effects of anticonvulsants and the effects on pregnancy and birth.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Cleft Lip; Cleft Palate; Cyclohexanes; Epilepsy; Ethosuximide; Female; Humans; Hydantoins; Male; Mutation; Obstetric Labor Complications; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Propylamines | 1973 |
Quantitative TLC determination of primidone, phenylethylmalonediamide, and phenobarbital in biological fluids.
Topics: Amides; Animals; Chromatography, Thin Layer; Dogs; Malonates; Methods; Phenobarbital; Primidone; Time Factors | 1973 |
Determination of primidone and its metabolites in biological fluids by gas chromatography.
Topics: Amides; Animals; Chromatography, Gas; Humans; Hydrogen-Ion Concentration; Malonates; Methods; Phenobarbital; Primidone; Rats; Temperature | 1973 |
[Complications of medical therapy for epilepsy in children and adolescents].
Topics: Anticonvulsants; Child; Diplopia; Drug Hypersensitivity; Drug Therapy, Combination; Epilepsy; Headache; Humans; Mental Disorders; Movement Disorders; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Primidone; Speech Disorders; Vertigo | 1973 |
[Antimetabolites of folic acid metabolism with chemotherapeutic activity against rodent malaria (Plasmodium vinckei)].
Topics: Aminopterin; Animals; Cycloheximide; Female; Folic Acid; Folic Acid Antagonists; Hydantoins; Malaria; Male; Methotrexate; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Plasmodium; Primidone; Pyrimethamine; Thalidomide; Triamterene | 1973 |
The influence of diphenylhydantoin on primidone metabolism.
Topics: Drug Interactions; Enzyme Induction; Female; Humans; Liver; Male; Phenobarbital; Phenytoin; Primidone | 1973 |
A rapid micro-method for determining four anti-convulsant drugs by gas-liquid chromatography.
Topics: Animals; Anticonvulsants; Carbon Radioisotopes; Chromatography, Gas; Evaluation Studies as Topic; Horses; Methods; Microchemistry; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Time Factors; Urea | 1973 |
Rickets associated with anticonvulsant medication.
Topics: Alkaline Phosphatase; Calcium; Child, Preschool; Female; Humans; Phenobarbital; Phenytoin; Phosphorus; Primidone; Rickets; Seizures; Vitamin D | 1974 |
Acute primidone intoxication.
Topics: Amides; Biotransformation; Brain; Chromatography, Thin Layer; Crystallization; Electroencephalography; Evoked Potentials; Half-Life; Malonates; Neurologic Manifestations; Phenobarbital; Photic Stimulation; Poisoning; Primidone | 1974 |
The influence of diphenylhydantoin on primidone metabolism.
Topics: Adult; Biotransformation; Chromatography, Gas; Drug Interactions; Enzyme Induction; Epilepsy; Female; Humans; Hydroxylation; Liver; Male; Oxidation-Reduction; Phenobarbital; Phenytoin; Primidone; Regression Analysis | 1974 |
Folate metabolism and anticonvulsant therapy.
Topics: Anticonvulsants; Blood-Brain Barrier; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone; Vitamin B 12 | 1974 |
Infants exposed in utero to antiepileptic drugs. A prospective study.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Amitriptyline; Amniotic Fluid; Anticonvulsants; Chromatography, Gas; Diazepam; Epilepsy; Ethosuximide; Female; Fetus; Growth Disorders; Humans; Hydantoins; Infant, Newborn; Mass Spectrometry; Mephobarbital; Meprobamate; Milk, Human; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Prochlorperazine; Prospective Studies; Substance Withdrawal Syndrome; Succinimides; Time Factors | 1974 |
Letter: GLC microdetermination of plasma anticonvulsant levels.
Topics: Anticonvulsants; Chromatography, Gas; Ethosuximide; Humans; Methods; Phenobarbital; Phenytoin; Primidone; Trimethadione | 1974 |
Pharmacology for the pediatrician. Noncompliance contributing to apparent drug failure in status epilepticus.
Topics: Anticonvulsants; Benzodiazepinones; Child; Chlorobenzenes; Diazepam; Epilepsy; Ethosuximide; Female; Humans; Medical Records; Medication Errors; Nitro Compounds; Phenobarbital; Phenytoin; Primidone | 1974 |
Antiepileptic drugs: a current assessment of simultaneous determination of multiple drug therapy by gas liquid chromatography-on column methylation.
Topics: Adult; Anticonvulsants; Autoanalysis; Barbiturates; Buffers; Child; Chromatography, Gas; Humans; Methods; Methylation; Microchemistry; Phenobarbital; Phenytoin; Primidone; Solvents; Temperature | 1974 |
Decrease in serum diphenylhydantoin levels after withdrawal of phenobarbital in epileptics treated with both drugs.
Topics: Child; Child, Preschool; Chromatography, Gas; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1974 |
Serum levels of diphenylhydantoin and phenobarbital in epileptic children receiving diphenylhydantoin, phenobarbital and-or mysoline.
Topics: Adolescent; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Primidone | 1974 |
Serum anticonvulsant concentrations in epileptic patients with mental symptoms. A preliminary report.
Topics: Adolescent; Adult; Aged; Epilepsy; Female; Humans; Intelligence; Male; Mental Disorders; Middle Aged; Personality Disorders; Phenobarbital; Phenytoin; Primidone; Psychomotor Disorders | 1974 |
Human brain, cerebrospinal fluid, and plasma concentrations of diphenylhydantoin and phenobarbital.
Topics: Adolescent; Adult; Brain Chemistry; Child, Preschool; Chromatography, Gas; Epilepsy, Temporal Lobe; Female; Humans; Male; Nerve Tissue Proteins; Phenobarbital; Phenytoin; Primidone; Protein Binding; Temporal Lobe; Ultrafiltration | 1974 |
Erythrocyte uptake and plasma binding of diphenylhydantoin.
Topics: Carbon Radioisotopes; Dialysis; Erythrocytes; Ethosuximide; Female; Hematocrit; Humans; Hydroxylation; Liver Cirrhosis; Male; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Protein Binding; Sulfamethoxypyridazine; Time Factors; Uremia | 1974 |
Delivery of anticonvulsant drug therapy in epileptic patients assessed by plasma level analyses.
Topics: Adolescent; Adult; Child; Chromatography, Gas; Drug Therapy; Electroencephalography; Epilepsy; Humans; Institutional Practice; Middle Aged; Phenobarbital; Phenytoin; Primidone; Recurrence; Time Factors | 1974 |
Epilepsy in Iceland. A clinical and epidemiological investigation.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Automobile Driving; Child; Child, Preschool; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Hydantoins; Iceland; Infant; Infant, Newborn; Intelligence; Male; Marriage; Mental Disorders; Middle Aged; Personality; Phenobarbital; Primidone; Prognosis | 1966 |
[Treatment of epilepsy in children].
Topics: Anticonvulsants; Child; Child, Preschool; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Hydantoins; Infant; Phenobarbital; Primidone | 1967 |
[On the combination treatment of epileptic attacks].
Topics: Anticonvulsants; Drug Synergism; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Hydantoins; Phenobarbital; Primidone | 1968 |
[Results of treatment of epilepsy in children up to 14 years of age].
Topics: Adolescent; Age Factors; Barbiturates; Child; Child, Preschool; Diazepam; Drug Synergism; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Infant; Phenobarbital; Phenytoin; Primidone | 1971 |
Colorimetric determination of C-10 hydroxylated metabolites of cyheptamide: application to absorption and enzyme induction studies in the rat.
Topics: Administration, Oral; Amides; Anticonvulsants; Benzocycloheptenes; Carbon Isotopes; Colorimetry; Dibenzocycloheptenes; Enzyme Induction; Hydrolysis; Hydroxylation; Lactones; Light; Phenobarbital; Primidone; Spectrum Analysis; Time Factors | 1972 |
Influence of certain anticonvulsants on the concentration of -aminobutyric acid in the cerebral hemispheres of mice.
Topics: Aminobutyrates; Animals; Anticonvulsants; Barbiturates; Brain Chemistry; Drug Antagonism; Drug Interactions; Hydantoins; Isoniazid; Male; Mice; Phenobarbital; Phenytoin; Primidone; Stimulation, Chemical | 1972 |
Coarse facies, calvarial thickening and hyperphosphatasia associated with long-term anticonvulsant therapy.
Topics: Adolescent; Adult; Alkaline Phosphatase; Anticonvulsants; Child; Diazepam; Ethosuximide; Facial Expression; Gingival Hyperplasia; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Skull; Time Factors | 1972 |
An isothermal GLC determination of the plasma levels of carbamazepine, diphenylhydantoin, phenobarbitone and primidone.
Topics: Benzyl Compounds; Carbamazepine; Chloroform; Chromatography, Gas; Humans; Methods; Phenobarbital; Phenytoin; Phthalic Acids; Primidone; Solubility; Spectrophotometry; Ultraviolet Rays | 1972 |
Altered calcium metabolism due to anticonvulsant drugs.
Topics: Adolescent; Alkaline Phosphatase; Anticonvulsants; Arthrography; Calcium; Calcium Metabolism Disorders; Child; Child, Preschool; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Phosphates; Primidone; Succinimides; Vitamin D | 1972 |
Long-term administration of antiepileptic drugs and the development of rickets.
Topics: Alkaline Phosphatase; Anticonvulsants; Calcium; Diazepam; Ethosuximide; Female; Gluconates; Humans; Infant; Mephobarbital; Osteomalacia; Phenobarbital; Phenytoin; Phosphorus; Primidone; Radiography; Rickets; Seizures; Time Factors; Trimethadione; Vitamin D | 1972 |
Antiepileptic drug concentrations in plasma. Clinical evaluation of 321 estimations in 237 unselected patients.
Topics: Carbamazepine; Chromatography, Gas; Chromatography, Thin Layer; Epilepsy; Humans; Methods; Phenobarbital; Phenytoin; Primidone | 1972 |
Treatment of epilepsy in the light of determinations of the blood levels of anticonvulsants.
Topics: Adult; Child; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1972 |
[Problem of drug-induced cerebral reactions: a case of myoclonic state under treatment with tricyclic antidepressive agents].
Topics: Adult; Amitriptyline; Bipolar Disorder; Chlordiazepoxide; Dibenzazepines; Electrocardiography; Female; Humans; Myoclonus; Phenobarbital; Primidone; Propylamines; Thioridazine | 1972 |
GLC determination of carbamazepine in plasma.
Topics: Benzocycloheptenes; Carbamates; Carbamazepine; Chromatography, Gas; Humans; Methods; Phenobarbital; Phenytoin; Primidone | 1972 |
[Speech disorders in children with cerebral convulsions].
Topics: Adolescent; Barbiturates; Carbamazepine; Drug Hypersensitivity; Electroencephalography; Epilepsy; Ethosuximide; Humans; Male; Phenobarbital; Phenytoin; Primidone; Speech Disorders; Speech Therapy; Verbal Behavior | 1972 |
Rickets following anticonvulsant therapy.
Topics: Child, Preschool; Humans; Infant; Male; Phenobarbital; Phenytoin; Primidone; Rickets; Vitamin D | 1972 |
[Treatment of epilepsy in the light of the determination of the anticonvulsant blood level].
Topics: Administration, Oral; Age Factors; Anticonvulsants; Drug Synergism; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Sex Factors; Time Factors | 1971 |
[Follow-up examinations of epileptic children who interrupted treatment of their own volition].
Topics: Age Factors; Anticonvulsants; Child; Child, Preschool; Drug Synergism; Electroencephalography; Epilepsy; Follow-Up Studies; Humans; Hydantoins; Infant; Oxyphenbutazone; Phenobarbital; Primidone; Prognosis; Time Factors | 1971 |
[Hematological control in the treatment of epilepsy].
Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Child; Epilepsy; Female; Folic Acid; Hematologic Diseases; Hematopoietic System; Humans; Hydantoins; Leukopenia; Male; Middle Aged; Phenobarbital; Primidone | 1971 |
Bone density in patients receiving long-term anticonvulsant therapy.
Topics: Absorptiometry, Photon; Adult; Alkaline Phosphatase; Anticonvulsants; Calcium; Carbamazepine; Epilepsy; Female; Forearm; Heel; Humans; Iodine Radioisotopes; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Phosphorus; Primidone | 1971 |
[Anticonvulsants. 1. Chemical survey].
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Chemical Phenomena; Chemistry; Diazepam; Hydantoins; Phenobarbital; Primidone; Pyrrolidines; Trimethadione | 1971 |
Variation in response to anticonvulsants in a group of epileptic patients.
Topics: Epilepsy, Temporal Lobe; Female; Humans; Male; Mental Disorders; Phenobarbital; Phenytoin; Primidone | 1971 |
Anticonvulsant therapy, folic acid and vitamin B12 metabolism and mental symptoms.
Topics: Adult; Anemia, Macrocytic; Female; Folic Acid Deficiency; Humans; Male; Mental Disorders; Middle Aged; Phenobarbital; Phenytoin; Primidone; Seizures; Vitamin B 12 Deficiency | 1966 |
Influence of ethylphenacemide on serum levels of other anti-epileptic drugs.
Topics: Adolescent; Adult; Benzazepines; Butyrates; Chromatography, Thin Layer; Colorimetry; Drug Synergism; Humans; Male; Phenobarbital; Phenytoin; Primidone; Urea | 1970 |
A clinical study of serum primidone levels.
Topics: Administration, Oral; Adolescent; Adult; Biotransformation; Child; Child, Preschool; Chromatography, Gas; Epilepsy; Female; Humans; Infant; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1970 |
Management of hemiplegic child. Role of neurologist.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Hemiplegia; Humans; Infant; Infant, Newborn; Phenobarbital; Phenytoin; Primidone | 1971 |
Anticonvulsant drugs and folic acid in young mentally retarded epileptic patients. A study of serum folate, fit frequency and I.Q.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Epilepsy; Ethosuximide; Female; Folic Acid; Humans; Intellectual Disability; Intelligence Tests; Male; Phenobarbital; Phenytoin; Primidone; Prognosis | 1971 |
Intolerance to diphenylhydantoin in five cases of Vogt-Spielmeyer disease.
Topics: Ataxia; Brain; Humans; L-Lactate Dehydrogenase; Lipidoses; Phenobarbital; Phenytoin; Primidone; Seizures | 1969 |
[Barbiturate poisoning via breast milk?].
Topics: Adult; Breast Feeding; Epilepsy; Female; Humans; Infant, Newborn; Milk, Human; Phenobarbital; Poisoning; Primidone | 1969 |
Central effects of diphenylhydantoin (dilantin) in epileptic oligophrenics during phenobarbital-primidone withdrawal, sodium bicarbonate, and ammonium chloride administration.
Topics: Adolescent; Adult; Ammonium Chloride; Bicarbonates; Epilepsy; Female; Humans; Hydrogen-Ion Concentration; Intellectual Disability; Lipidoses; Male; Phenobarbital; Phenytoin; Primidone; Sodium | 1969 |
[A rare case of severe poisoning with benzonal, hexamidine and luminal].
Topics: Adult; Barbiturates; Humans; Male; Phenobarbital; Primidone | 1969 |
Central effect of diphenylhydantoin (Dilantin) in epileptic oligophrenics during phenobarbital-primidone withdrawal, sodium bicarbonate, and ammonium chloride administration.
Topics: Adolescent; Adult; Ammonium Chloride; Bicarbonates; Epilepsy; Female; Humans; Hydrogen-Ion Concentration; Intellectual Disability; Lipidoses; Male; Phenobarbital; Phenytoin; Primidone; Sodium | 1969 |
Concurrent assay of phenobarbital and diphenylhydantoin in plasma by vapor-phase chromatography.
Topics: Chloroform; Chromatography, Gas; Humans; Hydrogen-Ion Concentration; Methods; Phenobarbital; Phenytoin; Primidone; Solubility; Time Factors | 1970 |
[Phenobarbital and diphenylhydantoin in the plasma and phenobarbital in the cerebrospinal fluid. II. Relationship between the determination of phenobarbital in the spinal fluid and phenobarbital in the plasma].
Topics: Adolescent; Child; Child, Preschool; Female; Humans; Infant; Male; Phenobarbital; Primidone | 1970 |
Disturbance of calcium metabolism by anticonvulsant drugs.
Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Anticonvulsants; Calcium Metabolism Disorders; Enzyme Induction; Epilepsy; Female; Humans; Hypocalcemia; Isoenzymes; Liver; Male; Middle Aged; Phenobarbital; Phenytoin; Phosphorus; Primidone; Vitamin D; Vitamin D Deficiency | 1970 |
Quantitative estimation of diphenylhydantoin, primidone and phenobarbital in plasma by gas-liquid chromatography.
Topics: Aniline Compounds; Chromatography, Gas; Hot Temperature; Humans; Methods; Methylation; Phenobarbital; Phenytoin; Primidone | 1970 |
The distribution of plasma phenytoin levels in epileptic patients.
Topics: Adult; Drug Tolerance; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1970 |
The importance of gastric lavage in the treatment of poisoning.
Topics: Amobarbital; Barbiturates; Chloroform; Chromatography, Thin Layer; Forensic Medicine; Gastric Lavage; Humans; Phenobarbital; Phenytoin; Poisoning; Primidone; Secobarbital | 1970 |
Rickets and anticonvulsant therapy in children: a roentgenologic investigation.
Topics: Adolescent; Anticonvulsants; Benzazepines; Child; Dextroamphetamine; Diazepam; Ethosuximide; Female; Hand; Humans; Knee; Male; Methylphenidate; Phenobarbital; Phenytoin; Primidone; Radiography; Rickets; Thioridazine; Time Factors | 1971 |
[Congenital abnormalities, cleft lip and cleft palate in particular, in children of epileptic mothers].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Cleft Lip; Cleft Palate; Epilepsy; Female; Humans; Infant, Newborn; Parity; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone | 1971 |
Gas chromatographic assay of underivatized 5,5-diphenylhydantoin (dilantin) in plasma extracts.
Topics: Carbamazepine; Chloroform; Chromatography, Gas; Coma; Epilepsy; Humans; Hydrogen-Ion Concentration; Methods; Phenobarbital; Phenytoin; Primidone | 1971 |
[Correlation between the prescribed dose of anti-epileptic agents and the blood levels measured].
Topics: Anticonvulsants; Carbamazepine; Humans; Phenobarbital; Phenytoin; Primidone | 1971 |
Urinary excretion of primidone and its metabolites in rabbits.
Topics: Amides; Animals; Carbon Isotopes; Chromatography, Thin Layer; Circadian Rhythm; Countercurrent Distribution; Female; Male; Malonates; Phenobarbital; Primidone; Rabbits; Spectrum Analysis; Time Factors; Ultraviolet Rays | 1968 |
Pseudolymphoma syndrome. A sensitivity to anticonvulsant drugs.
Topics: Biopsy; Blood Cell Count; Blood Chemical Analysis; Chlordiazepoxide; Drug Hypersensitivity; Female; Humans; Hydantoins; Hydrochlorothiazide; Lymphoma; Middle Aged; Phenobarbital; Phenytoin; Primidone; Seizures | 1968 |
Folic acid deficiency from anticonvulsant therapy.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Infant; Male; Mental Processes; Phenobarbital; Phenytoin; Primidone; Protein Biosynthesis | 1968 |
Mental effects of anticonvulsants, and folic acid metabolism.
Topics: Age Factors; Anemia, Macrocytic; Anticonvulsants; Brain; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Intellectual Disability; Male; Mental Disorders; Peripheral Nerves; Phenobarbital; Phenytoin; Primidone; Psychotic Disorders; Sex Factors; Spinal Cord; Vitamin B 12 | 1968 |
Thin-layer chromatography of anticonvulsant drugs.
Topics: Anticonvulsants; Chromatography, Thin Layer; Epilepsy; Humans; Hydantoins; Methods; Phenobarbital; Phenytoin; Primidone; Solvents; Time Factors | 1969 |
Clinico-electroencephalographic correlations in the course of epilepsy.
Topics: Adolescent; Adult; Age Factors; Brain; Electroencephalography; Epilepsy; Factor Analysis, Statistical; Humans; Hydantoins; Middle Aged; Phenobarbital; Primidone | 1969 |
Hyperglycemia with relative hypoinsulinemia in diphenylhydantoin toxicity.
Topics: Adolescent; Arginine; Blood Glucose; Female; Glucose; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Phenobarbital; Phenytoin; Primidone | 1969 |
Disposition of primidone in man: an example of autoinduction of a human enzyme system?
Topics: Enzyme Induction; Humans; Phenobarbital; Primidone | 1969 |
Gas chromatographic analysis for anticonvulsant drugs in biologic fluids.
Topics: Anticonvulsants; Chromatography, Gas; Equipment and Supplies; Humans; Hydantoins; Methods; Phenobarbital; Phenytoin; Primidone; Time Factors | 1969 |
Folic acid and anticonvulsive drugs.
Topics: Adolescent; Adult; Anticonvulsants; Epilepsy; Erythrocyte Count; Female; FIGLU Test; Folic Acid; Folic Acid Deficiency; Hematocrit; Humans; Male; Middle Aged; Neutrophils; Phenobarbital; Phenytoin; Primidone; Psychotic Disorders; Vitamin B 12 | 1969 |
Methylphenidate interaction with both anticonvulsants and ethyl biscoumacetate.
Topics: Adult; Anticonvulsants; Ataxia; Brain Diseases; Child, Preschool; Depression, Chemical; Ethyl Biscoumacetate; Humans; In Vitro Techniques; Infant; Liver; Male; Methylphenidate; Phenobarbital; Phenytoin; Primidone | 1969 |
A sequential screning test based on the running component of audiogenic seizures in mice, including reference compound PD50 values.
Topics: Acetazolamide; Animals; Anticonvulsants; Atropine; Chloral Hydrate; Chlordiazepoxide; Ethosuximide; Haloperidol; Hydroxybutyrates; Hypnotics and Sedatives; Meprobamate; Methods; Mice; Motor Activity; Orphenadrine; Phenobarbital; Phenytoin; Primidone; Sound | 1969 |
Quantitative determination of primidone in biological material.
Topics: Animals; Blood; Chemistry Techniques, Analytical; In Vitro Techniques; Phenobarbital; Primidone; Rats; Spectrophotometry; Ultraviolet Rays; Urine | 1965 |
Effect of primidone (mysoline) on tissular levels of griseofulvin in the rat.
Topics: Animals; Blood; Fluorometry; Griseofulvin; Liver; Phenobarbital; Primidone; Rats | 1965 |
[Therapeutic effect of mizodin and luminal in a case of Friedreich's paramyoclonus multiplex in a child].
Topics: Adolescent; Humans; Male; Myoclonus; Phenobarbital; Primidone | 1966 |
The estimation of some important anticonvulsant drugs in serum.
Topics: Anticonvulsants; Blood Chemical Analysis; Chemistry, Clinical; Chromatography, Thin Layer; Colorimetry; Humans; In Vitro Techniques; Phenobarbital; Phenytoin; Primidone | 1966 |
Drug-induced systemic lupus erythematosus. Primidone as a possible cause.
Topics: Electroencephalography; Epilepsy; Female; Humans; Hydralazine; Hydroxychloroquine; Lupus Erythematosus, Systemic; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1966 |
Disulfiramum (antabuse) as inhibitor of phenytoin metabolism.
Topics: Adult; Disulfiram; Drug Antagonism; Humans; Male; Phenobarbital; Phenytoin; Primidone; Spectrophotometry | 1966 |
The influence of disulfiram and calcium carbimide on the serum diphenylhydantoin. Excretion of HPPH in the urine.
Topics: Acetazolamide; Adult; Aged; Alcoholism; Amitriptyline; Chlordiazepoxide; Chlorpromazine; Chromatography, Thin Layer; Cyanates; Disulfiram; Drug Synergism; Epilepsy; Humans; Hydroflumethiazide; Imipramine; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1967 |
[Severe megaloblastic anemia due to anticonvulsants, sensitive to folic acid].
Topics: Adult; Anemia, Macrocytic; Epilepsy; Humans; Male; Phenobarbital; Primidone | 1967 |
Psychiatric implications of anticonvulsant drugs.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Humans; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1980 |
Choice of anticonvulsants in epilepsy.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Epilepsy; Ethosuximide; Follow-Up Studies; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1981 |
Primidone but not phenylethylmalonamide, a major metabolite, increases nerve-evoked transmitter release at the frog neuromuscular junction.
Topics: Animals; Electric Stimulation; In Vitro Techniques; Malonates; Motor Endplate; Neuromuscular Junction; Neurotransmitter Agents; Phenobarbital; Phenylethylmalonamide; Primidone; Rana pipiens; Synapses | 1982 |
The influence of antiepileptic drugs on the electroencephalogram: a review of controlled clinical studies.
Topics: Anti-Anxiety Agents; Anticonvulsants; Brain; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1982 |
[Rise in gamma-GT during anticonvulsive therapy].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Liver; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1982 |
An improved method for perfusion of the isolated brain of the rat-influence of perfusion conditions and application of analeptic and anticonvulsant drugs.
Topics: Adenosine Triphosphate; Animals; Anticonvulsants; Brain; Central Nervous System Stimulants; Lactates; Lactic Acid; Male; Pentylenetetrazole; Perfusion; Phenobarbital; Primidone; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Seizures | 1983 |
Pharmacokinetics of antiepileptic drugs.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Drug Interactions; Epilepsy; Ethosuximide; Female; Half-Life; Humans; Infant; Infant, Newborn; Intestinal Absorption; Kinetics; Male; Metabolic Clearance Rate; Phenobarbital; Phenytoin; Pregnancy; Primidone; Protein Binding; Valproic Acid | 1983 |
Pharmacodynamic factors in the occurrence of psychiatric symptoms among patients with epilepsy.
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Epilepsy; Folic Acid; Humans; Kinetics; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Valproic Acid; Vitamin B 12 | 1983 |
A rapid gas liquid chromatography method for simultaneous determination of various anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
Interactions between primidone, carbamazepine, and nicotinamide.
Topics: Animals; Carbamazepine; Child; Child, Preschool; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Half-Life; Humans; Infant; Male; Mice; Mice, Inbred Strains; Niacinamide; Phenobarbital; Phenylethylmalonamide; Primidone | 1982 |
Peripheral neuropathy in epileptic patients.
Topics: Epilepsy; H-Reflex; Humans; Neural Conduction; Peripheral Nervous System Diseases; Peroneal Nerve; Phenobarbital; Phenytoin; Primidone; Sural Nerve | 1981 |
Anticonvulsant peripheral neuropathy: a clinical and electrophysiological study of patients on single drug treatment with phenytoin, carbamazepine or barbiturates.
Topics: Adolescent; Adult; Aged; Barbiturates; Carbamazepine; Evoked Potentials, Somatosensory; Humans; Median Nerve; Middle Aged; Neural Conduction; Peripheral Nervous System Diseases; Phenobarbital; Phenytoin; Primidone; Sural Nerve | 1982 |
Logit-log calibration curves for EMIT assays.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Glucose-6-Phosphate; Glucosephosphates; Humans; Immunoenzyme Techniques; Kinetics; Mathematics; NAD; Phenobarbital; Phenytoin; Primidone; Spectrophotometry | 1983 |
Adaptation of microvolume EMIT assays for theophylline, phenobarbital, phenytoin, carbamazepine, primidone, ethosuximide, and gentamicin to a CentrifiChem chemistry analyzer.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Centrifugation; Ethosuximide; Gentamicins; Humans; Immunoenzyme Techniques; Microchemistry; Phenobarbital; Phenytoin; Primidone; Theophylline | 1983 |
Simultaneous measurement of ethosuximide, primidone, phenobarbital, phenytoin, carbamazepine, and their bioactive metabolites by liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Hydrogen-Ion Concentration; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone | 1984 |
Therapeutic monitoring of serum antiepileptic drug levels.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Humans; Laboratories; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Time Factors; Valproic Acid | 1983 |
Treatment of the nonconvulsive epilepsies.
Topics: Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1983 |
[Pharmacotherapy of epilepsy--current problems and controversies].
Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Post-Traumatic; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Humans; Infant; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Seizures, Febrile; Status Epilepticus; Valproic Acid | 1983 |
Effectiveness and toxicity of phenobarbital, primidone, and sodium valproate in the prevention of febrile convulsions, controlled by plasma levels.
Topics: Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Male; Phenobarbital; Primidone; Seizures, Febrile; Valproic Acid | 1984 |
Unnecessary polypharmacy in patients with frequent seizures.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
The place of saliva in antiepileptic drug monitoring.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Female; Humans; Middle Aged; Phenobarbital; Plasma; Primidone; Saliva; Valproic Acid | 1984 |
Enzyme induction in neonates after fetal exposure to antiepileptic drugs.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Anticonvulsants; Breath Tests; Carbamazepine; Carbon Radioisotopes; Enzyme Induction; Female; Humans; Infant, Newborn; Liver; Male; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1983 |
A comparative study of the relative enzyme inducing properties of anticonvulsant drugs in epileptic patients.
Topics: Anticonvulsants; Antipyrine; Carbamazepine; Enzyme Induction; Epilepsy; Female; Glucaric Acid; Half-Life; Humans; Immunoenzyme Techniques; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Pharmacologic therapy of seizures in the elderly.
Topics: Aged; Anticonvulsants; Carbamazepine; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Status Epilepticus; Valproic Acid | 1984 |
[Plasma levels of antiepileptic agents in the treatment of epilepsy].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
One drug for childhood grand mal: medical audit for three-year remissions.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Automated analysis of antiepileptic drugs in serum by column-switching high-performance liquid chromatography.
Topics: Anticonvulsants; Buffers; Calcium Chloride; Chromatography, High Pressure Liquid; Humans; Particle Size; Phenobarbital; Primidone | 1984 |
Primidone therapy in refractory neonatal seizures.
Topics: Drug Therapy, Combination; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Primidone; Seizures | 1984 |
[Simultaneous determination of 4 anticonvulsant drugs by high pressure liquid chromatography (HPLC)].
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Primidone | 1984 |
Excretion of organic acids associated with biotin deficiency in chronic anticonvulsant therapy.
Topics: Adult; Anticonvulsants; Biotin; Carbamazepine; Carboxy-Lyases; Carboxylic Acids; Epilepsy; Female; Humans; Male; Methylmalonyl-CoA Decarboxylase; Phenobarbital; Phenytoin; Primidone | 1984 |
Efficacy of primidone in dogs with seizures unresponsive to phenobarbital.
Topics: Animals; Dog Diseases; Dogs; Epilepsy; Female; Male; Phenobarbital; Primidone | 1984 |
Prognosis of chronic epilepsy with complex partial seizures.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Epilepsy, Temporal Lobe; Evoked Potentials; Humans; Phenobarbital; Phenytoin; Primidone; Prognosis | 1984 |
Single-dose kinetics of primidone in acute viral hepatitis.
Topics: Acute Disease; Adult; Biotransformation; Female; Hepatitis, Viral, Human; Humans; Kinetics; Male; Middle Aged; Phenobarbital; Primidone | 1984 |
The simultaneous determination of five anti-epileptic drugs in plasma by high performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1984 |
Mutagenicity of antiepileptic drugs. II. Phenytoin, primidone and phenobarbital.
Topics: Animals; Biotransformation; Cells, Cultured; Chromosome Aberrations; Cricetinae; Female; Mutation; Ovary; Phenobarbital; Phenytoin; Primidone; Sister Chromatid Exchange | 1984 |
Effects of primidone, phenobarbital and phenylethylmalonamide in the stimulated frog neuromuscular junction.
Topics: Action Potentials; Animals; Calcium; Electric Stimulation; In Vitro Techniques; Magnesium; Malonates; Motor Endplate; Neuromuscular Junction; Phenobarbital; Phenylethylmalonamide; Potassium; Primidone; Rana pipiens; Synapses | 1984 |
[Dupuytren's contracture and phenobarbital administration in epilepsy patients].
Topics: Adolescent; Adult; Bone Neoplasms; Dupuytren Contracture; Epilepsy; Female; Fibroma; Foot Diseases; Hand; Humans; Male; Middle Aged; Phenobarbital; Primidone; Soft Tissue Neoplasms | 1983 |
Reduction of polypharmacy for epilepsy in an institution for the retarded.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Intellectual Disability; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1983 |
Coma and crystalluria: a massive primidone intoxication treated with haemoperfusion.
Topics: Aged; Charcoal; Coma; Female; Half-Life; Hemoperfusion; Humans; Kinetics; Phenobarbital; Phenylethylmalonamide; Primidone | 1983 |
[Direct and indirect parameters of free thyroxine. I. Method, quality control and in vitro experiments on storage of samples and effect of drugs].
Topics: Aspirin; Blood Preservation; Drug Interactions; Humans; Phenobarbital; Phenytoin; Primidone; Quality Control; Radioimmunoassay; Thyroxine | 1983 |
PB:PRM ratio in patients with epilepsy treated with primidone.
Topics: Adolescent; Adult; Aging; Child; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Primidone | 1983 |
Primidone, phenobarbital, and PEMA: I. Seizure protection, neurotoxicity, and therapeutic index of individual compounds in mice.
Topics: Animals; Bicuculline; Brain; Brain Chemistry; Electroshock; Female; Malonates; Mice; Mice, Inbred Strains; Pentylenetetrazole; Phenobarbital; Phenylethylmalonamide; Primidone; Seizures | 1983 |
Primidone, phenobarbital, and PEMA: II. Seizure protection, neurotoxicity, and therapeutic index of varying combinations in mice.
Topics: Animals; Brain; Brain Chemistry; Drug Synergism; Drug Therapy, Combination; Electroshock; Female; Malonates; Mice; Mice, Inbred Strains; Pentylenetetrazole; Phenobarbital; Phenylethylmalonamide; Primidone; Seizures | 1983 |
A design for the prospective evaluation of the efficacy and toxicity of antiepileptic drugs in adults.
Topics: Adult; Aged; Anticonvulsants; Behavior; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Electroencephalography; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone; Random Allocation; Seizures | 1983 |
Antiepileptic agents--primidone, phenobarbital, phenytoin, and carbamazepine by reversed-phase liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Primidone; Statistics as Topic | 1984 |
Serum concentrations and efficacy of phenytoin, phenobarbital, and primidone in canine epilepsy.
Topics: Animals; Dog Diseases; Dogs; Drug Therapy, Combination; Epilepsy; Phenobarbital; Phenytoin; Primidone | 1984 |
Anticonvulsant effect of primidone in the gerbil. Time course and significance of the active metabolites.
Topics: Administration, Oral; Animals; Brain; Chromatography, Gas; Gerbillinae; Phenobarbital; Phenylethylmalonamide; Primidone; Seizures | 1984 |
Studies on the intracerebral metabolism of anticonvulsant drugs--I. Perfusion of primidone through the isolated brain of the rat.
Topics: Animals; Brain; In Vitro Techniques; Male; Perfusion; Phenobarbital; Phenylethylmalonamide; Primidone; Rats; Rats, Inbred Strains; Tissue Distribution | 1984 |
[Anticonvulsive combined therapy (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1980 |
Hepatotoxicity of sodium valproate and other anticonvulsants in rat hepatocyte cultures.
Topics: Animals; Anticonvulsants; Clonazepam; Culture Techniques; Dose-Response Relationship, Drug; L-Lactate Dehydrogenase; Liver; Phenobarbital; Phenytoin; Primidone; Rats; Valproic Acid | 1980 |
[Problems of therapeutic service in primidone therapy].
Topics: Adolescent; Drug Administration Schedule; Drug Interactions; Epilepsy, Tonic-Clonic; Female; Half-Life; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1980 |
Benign familial tremor treated with primidone.
Topics: Adolescent; Adult; Aged; Humans; Male; Middle Aged; Phenobarbital; Phenylethylmalonamide; Primidone; Propranolol; Prospective Studies; Tremor | 1981 |
Monotherapy or polytherapy for epilepsy?
Topics: Adolescent; Adult; Carbamazepine; Clonazepam; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1981 |
Valproic acid and plasma levels of primidone and derived phenobarbital.
Topics: Adult; Drug Interactions; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Female; Humans; Kinetics; Male; Phenobarbital; Primidone; Valproic Acid | 1981 |
Drug treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Seizures; Substance Withdrawal Syndrome; Valproic Acid | 1981 |
Phenobarbital, primidone and sodium valproate in the prophylaxis of febrile convulsions.
Topics: Child, Preschool; Dose-Response Relationship, Drug; Humans; Infant; Phenobarbital; Primidone; Recurrence; Seizures, Febrile; Valproic Acid | 1981 |
[The distribution of drugs between plasma, brain and cerebrospinal fluid in the human].
Topics: Blood-Brain Barrier; Brain; Brain Neoplasms; Carbamazepine; Diazepam; Humans; Lithium; Nordazepam; Phenobarbital; Phenytoin; Primidone; Protein Binding; Psychotropic Drugs; Serum Albumin; Sulfamerazine | 1982 |
EEG quantification of drug level effects in monkey model of partial epilepsy.
Topics: Animals; Anticonvulsants; Circadian Rhythm; Clonazepam; Disease Models, Animal; Electroencephalography; Kinetics; Macaca mulatta; Male; Phenobarbital; Phenytoin; Primidone; Seizures; Valproic Acid | 1982 |
Two antiepileptic drugs for intractable epilepsy with complex-partial seizures.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1982 |
[A study on cerebrospinal fluid and saliva to serum concentration ratios of anticonvulsants--Phenytoin, Phenobarbital, Valproic Acid and Primidone in epileptic patients].
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone; Saliva; Valproic Acid | 1982 |
Simultaneous very fast liquid-chromatographic analysis of ethosuximide, primidone, phenobarbital, phenytoin, and carbamazepine in serum.
Topics: Carbamazepine; Chromatography, Liquid; Economics; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1983 |
[Monitoring therapy by analysis of the drug concentration of saliva].
Topics: Anticonvulsants; Carbamazepine; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Saliva | 1983 |
Simultaneous liquid chromatographic determination of chloramphenicol and antiepileptic drugs (phenobarbital, phenytoin, carbamazepine, and primidone) in plasma.
Topics: Adult; Anticonvulsants; Carbamazepine; Chloramphenicol; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1983 |
Plasma levels of primidone and its metabolite phenobarbital: effect of age and associated therapy.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Male; Middle Aged; Phenobarbital; Primidone | 1983 |
Serum concentration of clonazepam and the therapeutic effect of the drug.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepinones; Clonazepam; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1983 |
Therapeutic serum concentrations of primidone and its metabolites, phenobarbital and phenylethylmalonamide in epileptic dogs.
Topics: Animals; Dog Diseases; Dogs; Epilepsy; Malonates; Phenobarbital; Phenylethylmalonamide; Primidone | 1983 |
Simultaneous high performance liquid-chromatographic determination of carbamazepine, carbamazepine-10,11-epoxide, ethosuximide, phenobarbital, phenytoin, primidone and phenylethylmalonamide in plasma.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1983 |
Improved isocratic liquid-chromatographic simultaneous measurement of phenytoin, phenobarbital, primidone, carbamazepine, ethosuximide, and N-desmethylmethsuximide in serum.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Reference Values; Succinimides | 1982 |
Quantitative simultaneous determination of eight common antiepileptic drugs and metabolites by liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Ethosuximide; Humans; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Succinimides | 1981 |
How worthwhile is plasma primidone level measurement?
Topics: Adolescent; Anticonvulsants; Female; Half-Life; Humans; Male; Phenobarbital; Primidone | 1981 |
On-line liquid-chromatographic analysis for drugs in serum with the Technicon "FAST-LC" system: performance data for theophylline and for four commonly used anticonvulsants and their metabolites.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Theophylline | 1980 |
[A gas-chromatographic method for the determination of carbamazepine, phenobarbital, phenytoin and primidone in the same extract of serum (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Temperature | 1980 |
Emit assays for five major anticonvulsant drugs. An evaluation of adaptations to two discrete kinetic analyzers.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, Gas; Cross Reactions; Ethosuximide; Evaluation Studies as Topic; Humans; Immunoenzyme Techniques; Indicators and Reagents; Phenobarbital; Phenytoin; Primidone | 1980 |
Rapid centrifugal analyzer enzyme immunoassays for phenytoin, phenobarbital, and primidone.
Topics: Computers; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Reagent Kits, Diagnostic | 1980 |
Enzyme immunoassay of phenobarbital, phenytoin, primidone, carbamazepine and theophylline with the Abbott VP Bichromatic Analyzer.
Topics: Carbamazepine; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Theophylline | 1981 |
[The determination of anticonvulsant drug levels in blood by enzyme immunoassay: method and clinical application (author's transl)].
Topics: Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Humans; Immunoenzyme Techniques; Male; Phenobarbital; Phenytoin; Primidone | 1980 |
Monitoring of therapeutic serum concentrations of antiepileptic drugs by a newly developed gas chromatographic procedure and enzyme immunoassay (EMIT): a comparative study.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Quality Control | 1981 |
Phenytoin: an inhibitor and inducer of primidone metabolism in an epileptic patient.
Topics: Adult; Drug Interactions; Epilepsy; Female; Humans; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1982 |
Hepatic cirrhosis associated with long-term anticonvulsant drug therapy in dogs.
Topics: Animals; Anticonvulsants; Dog Diseases; Dogs; Female; Liver; Liver Cirrhosis; Male; Microscopy, Electron; Phenobarbital; Phenytoin; Primidone | 1982 |
Plasma levels and clinical effects of antiepileptic drugs in pregnant epileptic patients and their newborns.
Topics: Adult; Anticonvulsants; Clonazepam; Epilepsy; Female; Humans; Infant, Newborn; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone | 1980 |
A possible neurochemical basis of the central stimulatory effects of pp'DDT.
Topics: Acetylcholine; Aminooxyacetic Acid; Ammonia; Animals; Central Nervous System; Corpus Striatum; DDT; gamma-Aminobutyric Acid; Hydroxylamines; Male; Mephobarbital; Mice; Phenobarbital; Primidone; Pyridoxine; Seizures | 1981 |
The effects of phenytoin on phenobarbitone and primidone metabolism.
Topics: Adult; Aged; Anticonvulsants; Drug Therapy, Combination; Humans; Middle Aged; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1981 |
[Phenobarbital intoxication in a patient with primidone and diphenylhydantoin (author's transl)].
Topics: Adult; Drug Interactions; Epilepsy; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1980 |
Serum concentrations of primidone and its metabolites, phenylethylmalonamide and phenobarbital, in the dog.
Topics: Animals; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Half-Life; Kinetics; Male; Malonates; Phenobarbital; Phenylethylmalonamide; Primidone | 1980 |
Rapid determination of anticonvulsant drugs by isothermal gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone | 1981 |
Ictal effects of anticonvulsant medication withdrawal in epileptic patients.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone; Substance Withdrawal Syndrome | 1981 |
Rapid microanalysis of anticonvulsants by high-performance thin-layer chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Thin Layer; Humans; Phenobarbital; Phenytoin; Primidone; Reference Values | 1981 |
[Gas chromatographic determination of phenytoin, phenobarbital and primidone: flash-methylation after direct addition of trimethyl-phenyl-ammonium hydroxide to the ethyl acetate extract (author's transl)].
Topics: Aniline Compounds; Chromatography, Gas; Humans; Methylation; Phenobarbital; Phenytoin; Primidone; Quaternary Ammonium Compounds | 1981 |
Effect of anticonvulsant and antidepressant drugs on iodothyronines in serum.
Topics: Adult; Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Dose-Response Relationship, Drug; Female; Humans; Male; Mianserin; Phenobarbital; Phenytoin; Primidone; Thyroid Hormones | 1980 |
GC and GC-mass spectrometric determination of p-hydroxyphenobarbital extracted from plasma, urine, and hepatic microsomes.
Topics: Animals; Biotransformation; Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Humans; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Phenobarbital; Primidone; Rats | 1981 |
Antiepileptic drug levels and side effects in man.
Topics: Anticonvulsants; Electroencephalography; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
Role of carbamazepine in reducing polypharmacy in epilepsy.
Topics: Acetazolamide; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1981 |
Spectrophotometric determination of phenytoin in the presence of other anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Diazepam; Humans; Phenobarbital; Phenytoin; Primidone; Spectrophotometry, Ultraviolet | 1981 |
Improvement in antiepileptic drug levels following reduction of intervals between clinic visits.
Topics: Adolescent; Adult; Anticonvulsants; Appointments and Schedules; Carbamazepine; Epilepsy; Ethosuximide; Female; Humans; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1980 |
Measurement of anticonvulsants in serum by reversed-phase ion-pair liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Urea | 1980 |
Antiepileptic drug distribution in cerebral cortex, ammon's horn, and amygdala in man.
Topics: Adolescent; Adult; Amygdala; Anticonvulsants; Carbamazepine; Cerebral Cortex; Child; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1980 |
Improved gas--liquid chromatographic method for the simultaneous determination of phenobarbital, phenytoin, carbamazepine and primidone in biological fluids.
Topics: Carbamazepine; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
Microassay for primidone and its metabolites phenylethylmalondiamide, phenobarbital and p-hydroxyphenobarbital in human serum, saliva, breast milk and tissues by gas chromatography--mass spectrometry using selected ion monitoring.
Topics: Female; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Kinetics; Malonates; Maternal-Fetal Exchange; Microchemistry; Milk, Human; Phenobarbital; Phenylethylmalonamide; Pregnancy; Primidone; Saliva | 1980 |
High performance liquid chromatographic analysis of anti-convulsant drugs using radial compression columns.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
Placental transfer and pharmacokinetics of primidone and its metabolites phenobarbital, PEMA and hydroxyphenobarbital in neonates and infants of epileptic mothers.
Topics: Adult; Aminopyrine; Cytochrome P-450 Enzyme System; Epilepsy; Female; Half-Life; Humans; Hydroxylation; Infant; Infant, Newborn; Kinetics; Liver; Male; Malonates; Maternal-Fetal Exchange; Phenobarbital; Phenylethylmalonamide; Pregnancy; Pregnancy Complications; Primidone | 1980 |
[Rational control of calcium metabolism in children treated with anticonvulsants].
Topics: Adolescent; Anticonvulsants; Calcium; Child; Child, Preschool; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
[Biotransformation of some antiepileptic drugs (author's transl)].
Topics: Anticonvulsants; Biotransformation; Carbamazepine; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
[Is primidone more efficient than phenobarbital? An attempt at a pharmacological evaluation (author's transl)].
Topics: Animals; Dogs; Epilepsy; Humans; Phenobarbital; Phenylethylmalonamide; Primidone | 1980 |
Primidone kinetics: effects of concurrent drugs and duration of therapy.
Topics: Adolescent; Adult; Aged; Drug Therapy, Combination; Female; Humans; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Phenobarbital; Phenylethylmalonamide; Primidone; Seizures; Time Factors | 1981 |
Power spectral analysis of EEG characteristics during sleep in epileptics.
Topics: Adolescent; Adult; Carbamazepine; Circadian Rhythm; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Infant; Male; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Sleep, REM | 1981 |
Practical considerations in anticonvulsant therapy--Part 2.
Topics: Anticonvulsants; Benzodiazepines; Cost Control; Epilepsy; Ethosuximide; Humans; Monitoring, Physiologic; Patient Compliance; Patient Education as Topic; Pharmacists; Phenobarbital; Phenytoin; Primidone; Role; Valproic Acid | 1995 |
Comparison of community and institutional prescription of antiepileptic drugs for individuals with learning disabilities.
Topics: Adult; Ambulatory Care; Anticonvulsants; Cognition Disorders; Day Care, Medical; Drug Therapy, Combination; Drug Utilization; England; Epilepsy; Female; Humans; Institutionalization; Intellectual Disability; Intelligence; Male; Phenobarbital; Phenytoin; Primidone; Social Behavior; State Medicine | 1994 |
Simultaneous determination of primidone and its active metabolites in rat plasma by high-performance liquid chromatography using a solid-phase extraction technique.
Topics: Administration, Oral; Animals; Calibration; Chemical Phenomena; Chemistry Techniques, Analytical; Chemistry, Physical; Chromatography, High Pressure Liquid; Male; Phenobarbital; Phenylethylmalonamide; Primidone; Rats; Rats, Wistar | 1994 |
Epilepsy treatment in The Netherlands. Comparison of matched groups of two medical centres.
Topics: Adolescent; Adult; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Female; gamma-Aminobutyric Acid; Humans; Male; Netherlands; Phenobarbital; Phenytoin; Primidone; Quality of Health Care; Statistics, Nonparametric; Treatment Outcome; Valproic Acid; Vigabatrin | 1994 |
Primidone or phenobarbital use complicating disruptive behavior disorders.
Topics: Adolescent; Adolescent Behavior; Craniocerebral Trauma; Dangerous Behavior; Humans; Male; Mental Disorders; Phenobarbital; Primidone | 1994 |
Factors affecting the determination of drugs and endogenous low molecular mass compounds in human serum by micellar electrokinetic capillary chromatography with direct sample injection.
Topics: Anticonvulsants; Blood Chemical Analysis; Buffers; Capillary Action; Chromatography; Ethosuximide; Humans; Kinetics; Micelles; Molecular Weight; Naproxen; Osmolar Concentration; Phenobarbital; Phenytoin; Primidone | 1994 |
Simultaneous determination of felbamate, primidone, phenobarbital, carbamazepine, two carbamazepine metabolites, phenytoin, and one phenytoin metabolite in human plasma by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Felbamate; Humans; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Quality Control; Regression Analysis; Spectrophotometry, Ultraviolet | 1994 |
Determination of phenobarbital, ethosuximide, and primidone in human serum by micellar electrokinetic capillary chromatography with direct sample injection.
Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Electrophoresis; Enzyme Multiplied Immunoassay Technique; Ethosuximide; Fluorescence Polarization Immunoassay; Humans; Micelles; Phenobarbital; Primidone; Quality Control | 1993 |
Simultaneous determination of carbamazepine, phenytoin, phenobarbital, primidone and their principal metabolites by high-performance liquid chromatography with photodiode-array detection.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Saliva; Spectrophotometry, Ultraviolet | 1993 |
[Treatment of essential tremor].
Topics: Anti-Anxiety Agents; Anti-Dyskinesia Agents; Botulinum Toxins; Humans; Hypnotics and Sedatives; Methazolamide; Nimodipine; Parkinson Disease; Phenobarbital; Primidone; Propranolol; Sympatholytics; Thalamus; Tremor; Vasodilator Agents | 1995 |
Seizure control after chronic pharmacotherapy in epileptic disorders beginning after 40 years of age.
Topics: Adult; Age of Onset; Aged; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Primidone | 1995 |
Nonconvulsive status epilepticus.
Topics: Anticonvulsants; Dizziness; Electroencephalography; Emergency Service, Hospital; Epilepsy, Tonic-Clonic; Humans; Lorazepam; Male; Middle Aged; Neurologic Examination; Phenobarbital; Primidone; Status Epilepticus; Valproic Acid | 1997 |
Neutropenia and thrombocytopenia in three dogs treated with anticonvulsants.
Topics: Anemia; Animals; Anticonvulsants; Bacteremia; Blood Cell Count; Dog Diseases; Dogs; Female; Male; Neutropenia; Phenobarbital; Primidone; Seizures; Thrombocytopenia | 1998 |
Physiologically based pharmacokinetics model of primidone and its metabolites phenobarbital and phenylethylmalonamide in humans, rats, and mice.
Topics: Animals; Anticonvulsants; Humans; Mice; Models, Biological; Phenobarbital; Phenylethylmalonamide; Primidone; Rats; Species Specificity | 1998 |
["Primary" orthostatic tremor. 10 clinical electrophysiologic observations].
Topics: Adult; Aged; Anti-Anxiety Agents; Arm; Clonazepam; Diazepam; Electromyography; Female; Humans; Leg; Male; Middle Aged; Muscle, Skeletal; Neurologic Examination; Phenobarbital; Posture; Primidone; Syndrome; Tremor; Weight-Bearing | 1998 |
Therapeutic serum drug concentrations in epileptic dogs treated with potassium bromide alone or in combination with other anticonvulsants: 122 cases (1992-1996).
Topics: Animals; Anticonvulsants; Bromides; Dog Diseases; Dogs; Drug Therapy, Combination; Epilepsy; Follow-Up Studies; Phenobarbital; Potassium Compounds; Primidone; Retrospective Studies; Treatment Outcome | 1998 |
Simultaneous determination of primidone and its three major metabolites in rat urine by high-performance liquid chromatography using solid-phase extraction.
Topics: Animals; Anticonvulsants; Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Phenobarbital; Phenylethylmalonamide; Primidone; Rabbits; Rats; Rats, Sprague-Dawley; Reproducibility of Results | 1998 |
Homocysteine concentrations and methionine loading in patients on antiepileptic drugs.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Case-Control Studies; Cytochrome P-450 Enzyme System; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Phenobarbital; Phenytoin; Primidone; Treatment Outcome; Valproic Acid; Vitamin B 12 | 2000 |
Effects of encapsulation of primidone on its oxidative metabolism in rats.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry, Physical; Drug Compounding; Feces; Female; Nanotechnology; Oxidation-Reduction; Phenobarbital; Phenylethylmalonamide; Polyesters; Primidone; Rats; Rats, Sprague-Dawley | 2001 |
Determination of lamotrigine simultaneously with carbamazepine, carbamazepine epoxide, phenytoin, phenobarbital, and primidone in human plasma by SPME-GC-TSD.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Lamotrigine; Phenobarbital; Phenytoin; Primidone; Triazines | 2002 |
Prediction of adsorption from multicomponent solutions by activated carbon using single-solute parameters. Part II--Proposed equation.
Topics: Adsorption; Body Fluids; Charcoal; Chromatography, High Pressure Liquid; Gastrointestinal Contents; Mephobarbital; Models, Chemical; Pancreatin; Phenobarbital; Predictive Value of Tests; Primidone; Solutions; Thermodynamics | 2002 |
Effects of liver damage and nephrectomy on anticonvulsant activity of mysoline and phenobarbital.
Topics: Anticonvulsants; Barbiturates; Humans; Kidney; Liver; Nephrectomy; Phenobarbital; Primidone | 1954 |
Metabolic conversion of primidone (mysoline) to phenobarbital.
Topics: Anticonvulsants; Humans; Phenobarbital; Primidone | 1956 |
[Experimental and clinical results of certain recent antiepileptic substances (doriden, gemonil, hibicon, milontin, mysoline and trinurid)].
Topics: Anticonvulsants; Barbiturates; Glutethimide; Humans; Phenobarbital; Primidone; Succinimides; Urea | 1957 |
Megaloblastic anaemia occurring during treatment of epilepsy with phenytoin sodium, primidone and phenobarbitone.
Topics: Anemia; Anemia, Megaloblastic; Anticonvulsants; Epilepsy; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone | 1957 |
Objective comparison of primidone and phenobarbital in epileptics.
Topics: Epilepsy; Humans; Phenobarbital; Primidone | 1957 |
Intoxication from primidone due to its biotransformation to phenobarbital.
Topics: Barbiturates; Biotransformation; Humans; Phenobarbital; Primidone | 1958 |
[Fatal poisoning (suicide) with mysoline and phenobarbital].
Topics: Humans; Medical Records; Phenobarbital; Primidone; Suicide | 1960 |
[Now and then: development of drug treatment of epilepsy since A. Hauptmann].
Topics: Anticonvulsants; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Pyrrolidinones | 1962 |
Increased activity of microsomal strychnine-metabolizing enzyme induced by phenobarbital and other drugs.
Topics: Glutethimide; Meprobamate; Nikethamide; Phenobarbital; Phenytoin; Primidone; Strychnine; Thiopental; Urethane | 1962 |
Treatment of epilepsy.
Topics: Acetazolamide; Anticonvulsants; Automatism; Child; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Primidone; Seizures | 1963 |
ANTIEPILEPTIC DRUGS.
Topics: Acetazolamide; Amphetamine; Amphetamines; Anticonvulsants; Barbiturates; Bromides; Epilepsy; Ethosuximide; Humans; Hydantoins; Mephobarbital; Meprobamate; Phenobarbital; Phenytoin; Primidone; Succinimides; Toxicology | 1963 |
MEGALOBLASTIC ANEMIA ASSOCIATED WITH THE USE OF ANTICONVULSANT DRUGS. REPORT OF A CASE AND REVIEW OF THE LITERATURE.
Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Toxicology | 1963 |
[USE OF SPOT ANALYSIS FOR THE DETECTION OF 5-PHENYL-5-ETHYL-2- THIOBARBITURIC ACID (THIOPHENOBARBITAL) AND 5-PHENYL-5-ETHYLBARBITURIC ACID (PHENOBARBITAL) IN ADDITION TO 5-PHENYL-5-ETHYLHEXAHYDROPYRIMIDINE-4,6-DIONE (PRIMIDONE)].
Topics: Barbiturates; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Pharmacy; Phenobarbital; Primidone; Research; Thiobarbiturates | 1963 |
MEGALOBLASTIC ANAEMIA ASSOCIATED WITH ANTICONVULSANT THERAPY.
Topics: Amobarbital; Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Barbiturates; Epilepsy; Folic Acid; Humans; Metabolism; Phenobarbital; Phenytoin; Primidone; Toxicology; Vitamin B 12 | 1963 |
MEGALOBLASTIC ANEMIA ASSOCIATED WITH THE INGESTION OF PHENOBARBITAL AND PRIMIDONE. REPORT OF A CASE IN A SIX-YEAR-OLD CHILD.
Topics: Anemia, Aplastic; Anemia, Macrocytic; Anemia, Megaloblastic; Anti-Bacterial Agents; Barbiturates; Candidiasis, Vulvovaginal; Child; Chloramphenicol; Epilepsy; Esophageal Stenosis; Intellectual Disability; Nitrofurantoin; Periodontal Diseases; Phenobarbital; Primidone; Sulfonamides; Toxicology | 1963 |
CURABLE MEDICAL DISEASES. THE NERVOUS SYSTEM. V. THE MANAGEMENT OF EPILEPSY.
Topics: Anticonvulsants; Central Nervous System Depressants; Epilepsy; Humans; Hydantoins; Phenobarbital; Primidone | 1963 |
ANTICONVULSANT DRUGS.
Topics: Anticonvulsants; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1964 |
SUBNORMAL SERUM FOLATE AND MACROCYTOSIS ASSOCIATED WITH ANTICONVULSANT DRUG THERAPY.
Topics: Anemia; Anemia, Macrocytic; Anticonvulsants; Biological Assay; Blood Chemical Analysis; Enterococcus faecalis; Epilepsy; Folic Acid; Folic Acid Antagonists; Humans; Lactobacillus; Phenobarbital; Phenytoin; Primidone; Toxicology; Vitamin B 12 | 1964 |
EPILEPSY AND LUPUS ERYTHEMATOSUS.
Topics: Acetazolamide; Amphetamine; Anticonvulsants; Child; Dexamethasone; Diagnosis; Epilepsy; Lupus Erythematosus, Systemic; Meningitis; Meningitis, Meningococcal; Phenobarbital; Prednisolone; Primidone; Pyridoxine; Succinimides; Toxicology | 1964 |
MEDICAL TREATMENT OF EPILEPSIES IN CHILDHOOD. A LONG-TERM SURVEY OF 801 PATIENTS.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Child; Electroencephalography; Epilepsy; Humans; Infant; Phenobarbital; Phenytoin; Primidone; Statistics as Topic | 1963 |
PSYCHOMOTOR VARIANT TYPE OF SEIZURE DISCHARGE.
Topics: Adolescent; Anticonvulsants; Child; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Temporal Lobe | 1963 |
[THERAPY OF EPILEPSY].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Chlordiazepoxide; Epilepsy; Epilepsy, Temporal Lobe; Humans; Infant; Infant, Newborn; Pharmacology; Phenobarbital; Primidone; Spasms, Infantile; Temporal Lobe; Toxicology | 1964 |
[TREATMENT OF EPILEPSY IN ADULTS. A BRIEF SURVEY OF THE CLINICAL PROBLEMS].
Topics: Acetazolamide; Anticonvulsants; Blood Chemical Analysis; Chloral Hydrate; Data Collection; Electroencephalography; Epilepsy; Heterocyclic Compounds; Neurosurgery; Neurosurgical Procedures; Phenobarbital; Phenytoin; Primidone; Psychology, Clinical; Social Medicine | 1964 |
[CONVULSIONS IN CHILDREN (3)].
Topics: Adolescent; Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Bromides; Child; Electroencephalography; Epilepsy; Humans; Infant; Infant, Newborn; Oxyphenbutazone; Phenobarbital; Primidone; Seizures | 1964 |
SEIZURES INDUCED BY MOVEMENT: A FORM OF REFLEX EPILEPSY.
Topics: Adolescent; Athetosis; Cerebral Angiography; Diagnosis, Differential; Electroencephalography; Epilepsy; Epilepsy, Reflex; Epilepsy, Tonic-Clonic; Humans; Neurologic Examination; Phenobarbital; Phenytoin; Primidone; Reflex; Reflex, Abnormal; Seizures; Spasm | 1964 |
REPORT ON THE ANTI-EPILEPTIC ACTION OF TEGRETOL.
Topics: Acetazolamide; Adolescent; Anticonvulsants; Biomedical Research; Carbamazepine; Child; Chlordiazepoxide; Drug Therapy; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Seizures; Temporal Lobe; Toxicology | 1964 |
ANTICONVULSANT DRUGS AND SELF-STIMULATING BEHAVIOR.
Topics: Anticonvulsants; Brain; Electric Stimulation; Electrophysiology; Hypothalamus; Learning; Pharmacology; Phenobarbital; Physiology; Primidone; Rats; Research | 1964 |
[INHIBITION OF ELECTROCONVULSION BY THE KAVA-PYRONES DIHYDROMETHYSTICIN AND DIHYDROKAVAIN].
Topics: Anticonvulsants; Chlorpromazine; Kava; Mice; Pharmacology; Phenobarbital; Phenytoin; Primidone; Pyrones; Rats; Research; Seizures | 1964 |
[THE PROSTRATION SYNDROME. SERIOUS DANGER OF DRUG THERAPY IN EPILEPSY].
Topics: Adolescent; Anticonvulsants; Chlorpromazine; Down Syndrome; Drug Therapy; Electroencephalography; Epilepsy; Epilepsy, Tonic-Clonic; Hydantoins; Phenobarbital; Primidone; Seizures; Toxicology | 1964 |
PAROXYSMAL SNEEZING.
Topics: Anticonvulsants; Child; Child Psychiatry; Epilepsy; Epilepsy, Temporal Lobe; Humans; Hydantoins; Methamphetamine; Phenobarbital; Primidone; Sneezing; Temporal Lobe | 1964 |
ANTICONVULSANTS. I. DIBENZO(A,D)CYCLOHEPTADIENE-5-CARBOXAMIDE AND RELATED COMPOUNDS.
Topics: Amides; Anticonvulsants; Ataxia; Chemistry, Pharmaceutical; Mice; Pentylenetetrazole; Pharmacology; Phenobarbital; Phenytoin; Primidone; Research; Seizures; Toxicology | 1964 |
IATROGENIC MEGALOBLASTIC ANAEMIA WITH NEUROLOGICAL COMPLICATIONS.
Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Brain Diseases; Cysticercosis; Drug Therapy; Epilepsy; Folic Acid; Humans; Iatrogenic Disease; Phenobarbital; Phenytoin; Primidone; Spinal Cord; Toxicology; Vitamin B 12 | 1964 |
HAEMORRHAGE ASSOCIATED WITH THROMBOCYTOPENIA IN MEGALOBLASTIC ANAEMIA.
Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Blood Platelet Disorders; Drug Therapy; Epilepsy; Female; Folic Acid; Hemorrhage; Humans; Phenobarbital; Pregnancy; Pregnancy Complications; Pregnancy Complications, Hematologic; Primidone; Thrombocytopenia; Toxicology; Vitamin B 12 | 1964 |
CHILD CARE IN GENERAL PRACTICE. CONVULSIONS IN INFANCY AND CHILDHOOD. II.
Topics: Acetazolamide; Anticonvulsants; Bromides; Child; Child Care; Chloral Hydrate; Diagnosis; Drug Therapy; Electroencephalography; Epilepsy; Ethosuximide; Family Practice; General Practice; Hospitalization; Humans; Infant; Oxyphenbutazone; Paraldehyde; Phenobarbital; Phenytoin; Primidone; Prognosis; Radiography; Seizures; Toxicology | 1965 |
[THE REPRODUCTION OF AUDIOGENIC CONVULSIONS AFTER THE PRELIMINARY ADMINISTRATION OF PYRAMIDONE TO ANIMALS].
Topics: Acetazolamide; Aminopyrine; Anticonvulsants; Antipyrine; Epilepsy, Reflex; Mice; Pharmacology; Phenobarbital; Phenytoin; Primidone; Rats; Research; Seizures; Sound; Toxicology | 1964 |
MEGALOBLASTIC ANAEMIA ASSOCIATED WITH ANTICONVULSANT DRUGS: STUDIES ON A CASE WITH FOUR RELAPSES.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Drug Therapy; Electrophoresis; Epilepsy; FIGLU Test; Folic Acid; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone; Recurrence; Toxicology; Urine | 1965 |
NEUROLOGICAL SEQUELAE FOLLOWING DILANTIN OVERDOSE IN A PATIENT AND IN EXPERIMENTAL ANIMALS.
Topics: Adolescent; Ataxia; Biomedical Research; Cats; Chlordiazepoxide; Drug Therapy; Epilepsy; Humans; Neurologic Manifestations; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Poisoning; Primidone; Rats; Toxicology | 1965 |
[Leukemia in an epileptic treated with gardenal and dihydan; recovery; fatal mysoline poisoning with fatty degeneration of the liver and acute epithelial nephritis].
Topics: Anticonvulsants; Barbiturates; Epilepsy; Humans; Hydantoins; Leukemia; Leukocytosis; Liver Diseases; Nephritis; Phenobarbital; Phenytoin; Poisoning; Primidone | 1955 |
Prediction of adsorption from multicomponent solutions by activated carbon using single-solute parameters.
Topics: Adsorption; Area Under Curve; Body Fluids; Charcoal; Gastrointestinal Contents; Mephobarbital; Models, Chemical; Molecular Structure; Phenobarbital; Predictive Value of Tests; Primidone; Solutions; Surface Properties | 2000 |
Epilepsy in the United Kingdom: seizure frequency and severity, anti-epileptic drug utilization and impact on life in 1652 people with epilepsy.
Topics: Adult; Aged; Anticonvulsants; Drug Utilization; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Primidone; Severity of Illness Index; Surveys and Questionnaires; United Kingdom | 2004 |
Anticonvulsant efficacy of the low-affinity partial benzodiazepine receptor agonist ELB 138 in a dog seizure model and in epileptic dogs with spontaneously recurrent seizures.
Topics: Animals; Anticonvulsants; Bromides; Chronic Disease; Disease Models, Animal; Dog Diseases; Dogs; Drug Therapy, Combination; Epilepsy; Flumazenil; GABA Agonists; GABA-A Receptor Agonists; Imidazoles; Pentylenetetrazole; Phenobarbital; Potassium Compounds; Primidone; Receptors, GABA-A; Seizures; Substance Withdrawal Syndrome; Treatment Outcome | 2004 |
Determination of levetiracetam in human plasma with minimal sample pretreatment.
Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Epilepsy; Humans; Lamotrigine; Levetiracetam; Phenobarbital; Piracetam; Primidone; Triazines | 2005 |
[Rapid analysis of antiepileptic drugs in human plasma by micellar electrokinetic capillary chromatography].
Topics: Anticonvulsants; Buffers; Carbamazepine; Chromatography, Micellar Electrokinetic Capillary; Clonazepam; Epilepsy; Humans; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Primidone; Sensitivity and Specificity; Sodium Dodecyl Sulfate | 2006 |
Optimization of solid-phase microextraction procedures for the determination of tricyclic antidepressants and anticonvulsants in plasma samples by liquid chromatography.
Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Chromatography, Liquid; Desipramine; Epoxy Compounds; Humans; Hydrogen-Ion Concentration; Imipramine; Lamotrigine; Nortriptyline; Phenobarbital; Phenylethylmalonamide; Polyurethanes; Primidone; Reproducibility of Results; Sensitivity and Specificity; Silanes; Time Factors; Triazines | 2006 |
Robust isocratic high performance liquid chromatographic method for simultaneous determination of seven antiepileptic drugs including lamotrigine, oxcarbazepine and zonisamide in serum after solid-phase extraction.
Topics: Analysis of Variance; Animals; Anticonvulsants; Carbamazepine; Cattle; Chromatography, High Pressure Liquid; Drug Monitoring; Ethosuximide; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Primidone; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Solutions; Specimen Handling; Spectrophotometry, Ultraviolet; Temperature; Triazines; Valproic Acid; Zonisamide | 2007 |
Continuous phenobarbital treatment leads to recurrent plantar fibromatosis.
Topics: Adult; Anticonvulsants; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Female; Fibroma; Foot Diseases; Humans; Magnetic Resonance Imaging; Male; Neoplasm Recurrence, Local; Neoplasms, Connective Tissue; Phenobarbital; Primidone | 2008 |
Drug-induced pertubation of the aminothiol redox-status in patients with epilepsy: improvement by B-vitamins.
Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Cysteine; Dipeptides; Drug Evaluation; Epilepsy; Female; Folic Acid; Humans; Hyperhomocysteinemia; Liver; Male; Methionine; Oxidation-Reduction; Phenobarbital; Phenytoin; Primidone; Pyridoxine; Riboflavin; Valproic Acid; Vitamin B Deficiency | 2008 |
Ambiguous results of an attempt to withdraw barbiturates in epilepsy patients with intellectual disability.
Topics: Anticonvulsants; Barbiturates; Cognition; Drug Therapy, Combination; Epilepsy; Humans; Intellectual Disability; Intelligence; Phenobarbital; Primidone; Seizures | 2009 |
Pharmacologic management of essential tremor.
Topics: Adrenergic beta-Antagonists; Aged; Anticonvulsants; Ethanol; Humans; Male; Phenobarbital; Primidone; Propranolol; Tremor | 2010 |
Antiepleptic drug interactions: a clinical case demonstration.
Topics: Adolescent; Anticonvulsants; Brain; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Phenobarbital; Primidone; Valproic Acid | 2011 |
Occurrence of psychoactive compounds and their metabolites in groundwater downgradient of a decommissioned sewage farm in Berlin (Germany).
Topics: Berlin; Gas Chromatography-Mass Spectrometry; Groundwater; Meprobamate; Phenobarbital; Phenylethylmalonamide; Primidone; Psychotropic Drugs; Pyridones; Sewage; Water Pollutants | 2012 |
Novel micro-extraction by packed sorbent procedure for the liquid chromatographic analysis of antiepileptic drugs in human plasma and urine.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Humans; Oxcarbazepine; Phenobarbital; Phenytoin; Primidone; Prohibitins; Sensitivity and Specificity; Solid Phase Extraction; Spectrophotometry, Ultraviolet | 2012 |
Occurrence and distribution of psychoactive compounds and their metabolites in the urban water cycle of Berlin (Germany).
Topics: Berlin; Environmental Monitoring; Filtration; Germany; Phenobarbital; Primidone; Sewage; Water Cycle; Water Pollutants, Chemical | 2012 |
How did phenobarbital's chemical structure affect the development of subsequent antiepileptic drugs (AEDs)?
Topics: Anticonvulsants; Carbamazepine; Drug Discovery; Epilepsy; Ethosuximide; History, 20th Century; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Structure-Activity Relationship; Succinimides; Valproic Acid | 2012 |
Characterization and application of restricted access carbon nanotubes in online extraction of anticonvulsant drugs from plasma samples followed by liquid chromatography analysis.
Topics: Adsorption; Animals; Anticonvulsants; Carbamazepine; Cattle; Chromatography, High Pressure Liquid; Equipment Design; Humans; Kinetics; Limit of Detection; Nanotubes, Carbon; Phenobarbital; Primidone; Prohibitins; Serum Albumin, Bovine | 2017 |