Compounds > phenobarbital

phenobarbital and pk 11195

phenobarbital has been researched along with pk 11195 in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's3 (37.50)18.2507
2000's2 (25.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Batt, AM; Herber, R; Siest, G; Strazielle, N; Totis, M; Wellman, M1
Fares, F; Gavish, M; Pick, CG; Weizman, A; Yanai, J1
Batt, AM; Gielen, J; Kremers, P; Siest, G; Totis, M; Van Cantfort, J1
Hänninen, O; Kaliste-Korhonen, E; Kärenlampi, S; Laaksonen, M1
Amiri, Z; Gavish, M; Katz, Y; Pick, CG; Weizman, R; Yanai, J1
Forshaw, PJ; Lister, T; Ray, DE1
Anderson, A; Beaudet, MJ; Roberge, C1
Bogdanović, RM; de Lange, EC; Eriksson, J; Lammertsma, AA; Michler, C; Potschka, H; Russmann, V; Syvänen, S; Voskuyl, RA; Windhorst, AD1

Other Studies

8 other study(ies) available for phenobarbital and pk 11195

ArticleYear
Effects of RP 52028 and phenobarbital on mRNA levels of inducible and constitutive sex-specific cytochrome P450 isozymes in rat liver.
    Biochemical pharmacology, 1991, Aug-08, Volume: 42, Issue:5

    Topics: Animals; Blotting, Northern; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Isoenzymes; Isoquinolines; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; RNA, Messenger; Sex Factors

1991
Chronic phenobarbital administration affects GABA and benzodiazepine receptors in the brain and periphery.
    European journal of pharmacology, 1989, Oct-10, Volume: 169, Issue:2-3

    Topics: Animals; Brain Chemistry; Flunitrazepam; Hippocampus; In Vitro Techniques; Isoquinolines; Kidney; Male; Membranes; Mice; Muscimol; Myocardium; Olfactory Bulb; Peripheral Nerves; Phenobarbital; Receptors, GABA-A

1989
Induction of liver microsomal cytochrome P-450 isozymes by 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinoline carboxamide.
    Xenobiotica; the fate of foreign compounds in biological systems, 1989, Volume: 19, Issue:8

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Blotting, Western; Cytochrome P-450 Enzyme System; Cytochromes b5; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Female; Immunochemistry; Isoenzymes; Isoquinolines; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains

1989
P450 enzyme CYP2B catalyzes the detoxification of diisopropyl fluorophosphate.
    Chemico-biological interactions, 1995, Mar-18, Volume: 94, Issue:3

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cell Line; Clotrimazole; Cricetinae; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Inactivation, Metabolic; Isoflurophate; Isoquinolines; Male; Metyrapone; Microsomes, Liver; NADP; Oxidoreductases; Phenobarbital; Rats; Rats, Wistar; Steroid Hydroxylases

1995
Effects of chronic prenatal, neonatal and adult exposure to barbiturates on mitochondrial benzodiazepine receptors in mouse testis.
    Biochemical pharmacology, 1994, Mar-02, Volume: 47, Issue:5

    Topics: Animals; Animals, Newborn; Female; Injections, Subcutaneous; Isoquinolines; Male; Mice; Mitochondria; Phenobarbital; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, GABA-A; Testis

1994
The role of voltage-gated chloride channels in type II pyrethroid insecticide poisoning.
    Toxicology and applied pharmacology, 2000, Feb-15, Volume: 163, Issue:1

    Topics: Animals; Chloride Channel Agonists; Chloride Channels; Insecticides; Ion Channel Gating; Isoquinolines; Ivermectin; Male; Mice; Motor Activity; Neuromuscular Junction; Nitriles; Patch-Clamp Techniques; Pentobarbital; Phenobarbital; Pyrethrins; Rats; Rats, Inbred F344

2000
GABA(A)/central benzodiazepine receptor and peripheral benzodiazepine receptor ligands as inducers of phenobarbital-inducible CYP2B and CYP3A.
    Biochemical pharmacology, 2004, Oct-01, Volume: 68, Issue:7

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Enzyme Induction; GABA Agents; GABA-A Receptor Agonists; Hepatocytes; Isoquinolines; Ligands; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Steroid Hydroxylases

2004
(R)-[11C]PK11195 brain uptake as a biomarker of inflammation and antiepileptic drug resistance: evaluation in a rat epilepsy model.
    Neuropharmacology, 2014, Volume: 85

    Topics: Animals; Anticonvulsants; Brain; Carbon Radioisotopes; Carrier Proteins; Chronic Disease; Disease Models, Animal; Drug Resistance; Electrodes, Implanted; Epilepsy, Temporal Lobe; Female; Isoquinolines; Microglia; Neuroimmunomodulation; Phenobarbital; Positron-Emission Tomography; Radiopharmaceuticals; Random Allocation; Rats, Sprague-Dawley; Receptors, GABA-A; Status Epilepticus

2014