phenobarbital has been researched along with pilocarpine in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (17.65) | 18.7374 |
| 1990's | 5 (14.71) | 18.2507 |
| 2000's | 10 (29.41) | 29.6817 |
| 2010's | 12 (35.29) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Di Gregorio, GJ; Knaiz, EK; Nagle, BT; Piraino, AJ | 1 |
| Weiss, H | 1 |
| Andrews, JS; Bortolotto, ZA; Bressler, K; Calderazzo-Filho, LS; Cavalheiro, EA; Löschmann, PA; Turski, L | 1 |
| Kaniike, K; Kurogochi, Y | 1 |
| Dey, PK; Mukherjee, A | 1 |
| Alphin, RS; Saunders, D; Ward, JW | 1 |
| Daniels, AH; Fujikawa, DG; Kim, JS | 1 |
| George, B; Kulkarni, SK | 1 |
| Ebinger, G; Michotte, Y; Smolders, I; Van Belle, K | 1 |
| George, B; Kulkarni, SK; Mathur, R | 1 |
| Esmaeil, N; Jones, DM; Macdonald, RL; Maren, S | 1 |
| Grimee, R; Klitgaard, H; Margineanu, DG; Matagne, A; Vanneste-Goemaere, J | 1 |
| ZABLOCKA, B | 1 |
| Jiao, Y; Nadler, JV | 1 |
| Assis, MA; Fonteles, MM; Freitas, RL; Freitas, RM; Pereira, MB; Silva, RF; Takahashi, RN | 1 |
| Liu, X; Yang, H; Yang, J; Yang, Z | 1 |
| Bankstahl, JP; Löscher, W | 1 |
| Good, LB; Marsh, ST; Treiman, DM; Wang, NC | 1 |
| Bauer, B; Gorter, JA; Hartz, AM; Pekcec, A; Potschka, H; Schlichtiger, J; Soerensen, J; Unkrüer, B; van Vliet, EA | 1 |
| Brandt, C; Heuchert, N; Löscher, W; Nozadze, M; Rattka, M | 1 |
| Bankstahl, JP; Bankstahl, M; Löscher, W | 1 |
| Brandt, C; Erker, T; Löscher, W; Töllner, K | 1 |
| Brandt, C; Bröer, S; Klee, R; Löscher, W; Töllner, K | 1 |
| Carvalho, AL; da Rocha Tomé, A; da Silva, JA; de Freitas, RM; Figueiredo, KA; Medeiros, SC; Neves, JK | 1 |
| Löscher, W | 1 |
| Brandt, C; Erker, T; Löscher, W; Schidlitzki, A; Schreppel, P; Töllner, K; Twele, F | 1 |
| Löscher, W; Töllner, K; Twele, F | 1 |
| Blanco, MM; Cinini, SM; Lima, TZ; Mello, LE; Pontes, JC; Queiroz, CM | 1 |
| Auvin, S; Baud, O; Bonnin, P; Charriaut-Marlangue, C; Dupuis, N; Enderlin, J; Leger, PL; Morin, L; Perrotte, G | 1 |
| Gailus, B; Gericke, B; Hampel, P; Johne, M; Kaczmarek, E; Löscher, W; Römermann, K | 1 |
2 review(s) available for phenobarbital and pilocarpine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Single versus combinatorial therapies in status epilepticus: Novel data from preclinical models.
Topics: Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Ketamine; Lithium; Phenobarbital; Pilocarpine; Rats; Seizures; Status Epilepticus | 2015 |
32 other study(ies) available for phenobarbital and pilocarpine
| Article | Year |
|---|---|
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Secretion of drugs by the parotid glands of rats and human beings.
Topics: Acetylcholine; Adult; Amobarbital; Animals; Barbiturates; Chlorpromazine; Codeine; Glutethimide; Humans; Male; Meprobamate; Methadone; Morphine; Narcotics; Parotid Gland; Pentobarbital; Phenobarbital; Pilocarpine; Rats; Saliva; Secobarbital; Tranquilizing Agents | 1977 |
[Dependence of the crystal growth of solids on the intensity of size reduction on the example of various pharmaceutical agents. 2].
Topics: Chloramphenicol; Crystallization; Pharmaceutical Preparations; Phenobarbital; Pilocarpine; Prednisolone; Temperature | 1977 |
Substantia nigra regulates action of antiepileptic drugs.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroencephalography; Ethosuximide; Male; Microinjections; Midazolam; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Inbred Strains; Seizures; Substantia Nigra; Trimethadione | 1990 |
[Effect of psychotropic drugs on the K + -dependent phosphatase activity in guinea pig brain microsomes].
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Chlordiazepoxide; Chlorpromazine; Desipramine; Diazepam; Guinea Pigs; Histamine; Hydroxyzine; Imipramine; Meprobamate; Microsomes; Morphine; Nialamide; Phenelzine; Phenobarbital; Phenoxybenzamine; Phosphoric Monoester Hydrolases; Pilocarpine; Potassium; Procaine; Reserpine; Tranquilizing Agents | 1972 |
Responses of the circulatory system towards the vasoactive drugs in hypothermia under different anesthesia.
Topics: Acetylcholine; Anesthesia; Animals; Blood Circulation; Cats; Epinephrine; Ergonovine; Heart; Histamine; Hypothermia; Male; Nicotine; Papaverine; Pentolinium Tartrate; Phenobarbital; Physostigmine; Pilocarpine; Urethane | 1967 |
Method for the evaluation of antihidrotic substances in the anesthetized cat.
Topics: Animals; Cats; Foot; Humidity; Phenobarbital; Pilocarpine; Sweating | 1967 |
The competitive NMDA receptor antagonist CGP 40116 protects against status epilepticus-induced neuronal damage.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Behavior, Animal; Brain; Diazepam; Electroencephalography; Lithium; Male; Neurons; Phenobarbital; Pilocarpine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Status Epilepticus | 1994 |
Protective effects of GABAergic drugs and other anticonvulsants in lithium-pilocarpine-induced status epilepticus.
Topics: Animals; Anticonvulsants; Baclofen; Clonazepam; Diazepam; Dizocilpine Maleate; Ethanol; GABA Agents; gamma-Aminobutyric Acid; Lithium Chloride; Male; Neuroprotective Agents; Pentobarbital; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Valproic Acid | 1996 |
Hippocampal and cerebellar extracellular amino acids during pilocarpine-induced seizures in freely moving rats.
Topics: Amino Acids; Animals; Aspartic Acid; Carbamazepine; Cerebellum; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Microdialysis; Phenobarbital; Pilocarpine; Rats; Rats, Wistar; Seizures | 1997 |
Development of self-sustaining limbic status epilepticus by continuous ventral hippocampal stimulation followed by low dose pilocarpine in rats.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dizocilpine Maleate; Electroencephalography; Hippocampus; Limbic System; Lithium; Male; Neuroprotective Agents; Phenobarbital; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus; Stereotyped Behavior | 1998 |
Characterization of pharmacoresistance to benzodiazepines in the rat Li-pilocarpine model of status epilepticus.
Topics: Animals; Anticonvulsants; Benzodiazepines; Chi-Square Distribution; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance; Electroencephalography; Lithium Chloride; Male; Muscarinic Agonists; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Status Epilepticus; Time Factors | 2002 |
Electrophysiological, neurochemical and regional effects of levetiracetam in the rat pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Aspartic Acid; Clonazepam; Electroencephalography; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hippocampus; Injections, Intraperitoneal; Levetiracetam; Male; Microinjections; Phenobarbital; Pilocarpine; Piracetam; Rats; Rats, Sprague-Dawley; Valproic Acid | 2003 |
Effects of autonomic agents, alone and in combination with antiepileptic drugs, on electroshock seizures in rats.
Topics: Animals; Anticonvulsants; Atropine; Autonomic Agents; Electroshock; Methacholine Compounds; Neostigmine; Phenobarbital; Phenytoin; Physostigmine; Pilocarpine; Rats; Seizures | 1963 |
Stereological analysis of GluR2-immunoreactive hilar neurons in the pilocarpine model of temporal lobe epilepsy: correlation of cell loss with mossy fiber sprouting.
Topics: Algorithms; Animals; Anticonvulsants; Cell Count; Cell Shape; Dentate Gyrus; Epilepsy, Temporal Lobe; Immunohistochemistry; Male; Mossy Fibers, Hippocampal; Muscarinic Agonists; Neurons; Phenobarbital; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Tissue Fixation | 2007 |
Study pharmacologic of the GABAergic and glutamatergic drugs on seizures and status epilepticus induced by pilocarpine in adult Wistar rats.
Topics: Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Ketamine; Male; Muscarinic Agonists; N-Methylaspartate; Phenobarbital; Pilocarpine; Rats; Rats, Wistar; Receptors, GABA; Receptors, Neurotransmitter; Seizures; Status Epilepticus; Vigabatrin | 2007 |
Increased P-glycoprotein expression and decreased phenobarbital distribution in the brain of pentylenetetrazole-kindled rats.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Brain; Brain Chemistry; Cerebral Cortex; Convulsants; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; Hypnotics and Sedatives; Kainic Acid; Kindling, Neurologic; Male; Muscarinic Agonists; Pentylenetetrazole; Phenobarbital; Pilocarpine; Rats; Rats, Sprague-Dawley; Rhodamine 123; Up-Regulation | 2007 |
Resistance to antiepileptic drugs and expression of P-glycoprotein in two rat models of status epilepticus.
Topics: Amygdala; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B; Diazepam; Disease Models, Animal; Drug Resistance; Electric Stimulation; Endothelium, Vascular; Female; Gene Expression Regulation; Genes, MDR; Hippocampus; Phenobarbital; Phenytoin; Pilocarpine; Quinolines; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2008 |
EEG stages predict treatment response in experimental status epilepticus.
Topics: Analysis of Variance; Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Disease Progression; Electroencephalography; Lithium Chloride; Male; Phenobarbital; Pilocarpine; Predictive Value of Tests; Rats; Rats, Sprague-Dawley; Reaction Time; Status Epilepticus; Time Factors | 2009 |
Targeting prostaglandin E2 EP1 receptors prevents seizure-associated P-glycoprotein up-regulation.
Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Capillaries; Electrodes, Implanted; Female; Image Processing, Computer-Assisted; Immunohistochemistry; Kindling, Neurologic; Muscarinic Agonists; Phenobarbital; Pilocarpine; Rats; Rats, Wistar; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Seizures; Status Epilepticus; Up-Regulation | 2009 |
Disease-modifying effects of phenobarbital and the NKCC1 inhibitor bumetanide in the pilocarpine model of temporal lobe epilepsy.
Topics: Amygdala; Analysis of Variance; Animals; Anticonvulsants; Behavior, Animal; Bumetanide; Cell Count; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy, Temporal Lobe; Female; Hippocampus; Immunohistochemistry; Motor Activity; Neurons; Phenobarbital; Pilocarpine; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Status Epilepticus | 2010 |
Inter-individual variation in the anticonvulsant effect of phenobarbital in the pilocarpine rat model of temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Exploratory Behavior; Female; Hippocampus; Hyperkinesis; Maze Learning; Muscarinic Agonists; Nerve Degeneration; Phenobarbital; Pilocarpine; Rats; Rats, Sprague-Dawley; Time Factors; Touch; Video Recording | 2012 |
Bumetanide is not capable of terminating status epilepticus but enhances phenobarbital efficacy in different rat models.
Topics: Animals; Anticonvulsants; Basolateral Nuclear Complex; Bumetanide; Disease Models, Animal; Drug Synergism; Electric Stimulation; Kainic Acid; Lithium; Male; Phenobarbital; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2015 |
Effective termination of status epilepticus by rational polypharmacy in the lithium-pilocarpine model in rats: Window of opportunity to prevent epilepsy and prediction of epilepsy by biomarkers.
Topics: Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Electrodes, Implanted; Electroencephalography; Female; Hippocampus; Lithium Chloride; Neurons; Phenobarbital; Pilocarpine; Polypharmacy; Rats, Sprague-Dawley; Scopolamine; Seizures; Status Epilepticus; Time Factors; Treatment Outcome | 2015 |
In vivo evaluation of anticonvulsant and antioxidant effects of phenobarbital microemulsion for transdermal administration in pilocarpine seizure rat model.
Topics: Administration, Cutaneous; Animals; Anticonvulsants; Antioxidants; Disease Models, Animal; Emulsions; Female; Hippocampus; Lipid Peroxidation; Oxidative Stress; Phenobarbital; Pilocarpine; Rats; Rats, Wistar; Seizures | 2015 |
The bumetanide prodrug BUM5, but not bumetanide, potentiates the antiseizure effect of phenobarbital in adult epileptic mice.
Topics: Animals; Anticonvulsants; Bumetanide; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroencephalography; Electroshock; Epilepsy, Temporal Lobe; Mice; Pentylenetetrazole; Phenobarbital; Pilocarpine; Prodrugs | 2016 |
Evaluation of the pentylenetetrazole seizure threshold test in epileptic mice as surrogate model for drug testing against pharmacoresistant seizures.
Topics: Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Drug Resistance; Epilepsy; GABA Antagonists; Levetiracetam; Male; Mice; Pentylenetetrazole; Phenobarbital; Pilocarpine; Piracetam; Rats; Seizures; Status Epilepticus; Valproic Acid | 2016 |
Seizures triggered by pentylenetetrazol in marmosets made chronically epileptic with pilocarpine show greater refractoriness to treatment.
Topics: Animals; Anticonvulsants; Brain; Callithrix; Carbamazepine; Chronic Disease; Disease Models, Animal; Electrocorticography; Epilepsy; Female; Immunohistochemistry; Male; Neuropeptide Y; Pentylenetetrazole; Phenobarbital; Pilocarpine; Proto-Oncogene Proteins c-fos; Seizures; Valproic Acid | 2016 |
Different response to antiepileptic drugs according to the type of epileptic events in a neonatal ischemia-reperfusion model.
Topics: Animals; Animals, Newborn; Anticonvulsants; Brain; Brain Ischemia; Disease Models, Animal; Epilepsy; Female; Levetiracetam; Lithium Compounds; Male; Phenobarbital; Pilocarpine; Piracetam; Random Allocation; Rats, Wistar; Reperfusion Injury; Stroke | 2017 |
Effects of the NKCC1 inhibitors bumetanide, azosemide, and torasemide alone or in combination with phenobarbital on seizure threshold in epileptic and nonepileptic mice.
Topics: Animals; Anticonvulsants; Bumetanide; Drug Therapy, Combination; Epilepsy; Female; Mice; Phenobarbital; Pilocarpine; Seizures; Sodium Potassium Chloride Symporter Inhibitors; Solute Carrier Family 12, Member 2; Sulfanilamides; Torsemide; Treatment Outcome | 2021 |