phenobarbital and phenanthrenes

phenobarbital has been researched along with phenanthrenes in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199015 (93.75)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chaturapit, S; Holder, GM1
Casciano, DA; Delclos, KB; el-Bayoumy, K; Hecht, SS; Kadlubar, FF; Mandal, S; Shivapurkar, N; Stoner, GD; Walker, RP1
Bao, ZP; Yang, SK1
Mushtaq, M; Yang, SK1
Kandaswami, C; Kumar, S; Rutkowski, JP; Sikka, HC1
Boehlert, C; Jerina, DM; Levin, W; Mirsadeghi, S; Pannell, LK; Ryan, DE; Sayer, JM; Thakker, DR; Thomas, PE; Yagi, H1
Boehlert, C; Byrd, RA; Mirsadeghi, S; Prasad, GK; Thakker, DR1
Bao, Z; Mushtaq, M; Yang, SK1
Saprin, AN; Serdiuk, OA; Sotnichenko, AI; Sukhanov, VA1
Bick, M; Fishbein, L1
Daly, J; Oesch, F1
Conney, AH; Croisy-Delcey, M; Ittah, Y; Jerina, DM; Levin, W; Ryan, DE; Thakker, DR; Thomas, PE1
Conney, AH; Jerina, DM; Levin, W; Ryan, DE; Thakker, DR; Thomas, PE; Vyas, KP; Yagi, H1
Conney, AH; Jerina, DM; Levin, W; Nordqvist, M; Ryan, DE; Thakker, DR; Thomas, PE; Vyas, KP; Yagi, H1
Conney, AH; Jerina, DM; Levin, W; Vyas, KP; Yagi, H1
Li, H; Lu, C; Shen, GL; Tan, Y; Xiao, WB; Zhuang, XM1

Other Studies

16 other study(ies) available for phenobarbital and phenanthrenes

ArticleYear
Studies on the hepatic microsomal metabolism of (14C) phenanthrene.
    Biochemical pharmacology, 1978, Volume: 27, Issue:14

    Topics: Animals; Guinea Pigs; In Vitro Techniques; Methylcholanthrene; Mice; Mice, Inbred DBA; Microsomes, Liver; Phenanthrenes; Phenobarbital; Rats; Species Specificity

1978
Metabolic activation of 6-nitrochrysene in explants of human bronchus and in isolated rat hepatocytes.
    Cancer research, 1989, Jun-01, Volume: 49, Issue:11

    Topics: Animals; Aroclors; Biotransformation; Bronchi; Chromatography, High Pressure Liquid; Chrysenes; DNA; Humans; Liver; Male; Methylcholanthrene; Oxidation-Reduction; Phenanthrenes; Phenobarbital; Rats; Rats, Inbred Strains

1989
Stereoselective formations of K-region and non-K-region epoxides in the metabolism of chrysene by rat liver microsomal cytochrome P-450 isozymes.
    Molecular pharmacology, 1987, Volume: 32, Issue:1

    Topics: Animals; Chromatography, High Pressure Liquid; Chrysenes; Cytochrome c Group; Epoxy Compounds; Ethers, Cyclic; Isoenzymes; Kinetics; Male; Microsomes, Liver; Phenanthrenes; Phenobarbital; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet

1987
Stereoselective metabolism of benzo[c]phenanthrene to the procarcinogenic trans-3,4-dihydrodiol.
    Carcinogenesis, 1987, Volume: 8, Issue:5

    Topics: Animals; Carcinogens; Circular Dichroism; Cytochrome P-450 Enzyme System; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Mutagens; Phenanthrenes; Phenobarbital; Polychlorinated Biphenyls; Rats; Rats, Inbred Strains; Stereoisomerism

1987
Comparative metabolism of phenanthrene and benzo[f]quinoline by rat liver microsomes.
    Cancer letters, 1988, Dec-15, Volume: 43, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Male; Methylcholanthrene; Microsomes, Liver; Phenanthrenes; Phenobarbital; Quinolines; Rats; Rats, Inbred Strains

1988
Differential stereoselectivity on metabolism of triphenylene by cytochromes P-450 in liver microsomes from 3-methylcholanthrene- and phenobarbital-treated rats.
    The Journal of biological chemistry, 1988, Jan-05, Volume: 263, Issue:1

    Topics: Animals; Chromatography, High Pressure Liquid; Chrysenes; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Oxygen Isotopes; Phenanthrenes; Phenobarbital; Rats; Stereoisomerism; Structure-Activity Relationship

1988
Oxidative metabolism of the carcinogen 6-fluorobenzo[c]phenanthrene. Effect of a K-region fluoro substituent on the regioselectivity of cytochromes P-450 in liver microsomes from control and induced rats.
    The Journal of biological chemistry, 1988, Mar-15, Volume: 263, Issue:8

    Topics: Animals; Binding Sites; Carcinogens; Cytochrome P-450 Enzyme System; Hydrocarbons, Fluorinated; Magnetic Resonance Spectroscopy; Male; Methylcholanthrene; Microsomes, Liver; Molecular Conformation; Oxidation-Reduction; Phenanthrenes; Phenobarbital; Protein Binding; Rats; Reference Values; Structure-Activity Relationship

1988
Reversed-phase high-performance liquid chromatographic separation of phenolic derivatives of benzo[a]pyrene, benz[a]anthracene, and chrysene with monomeric and polymeric C18 columns.
    Journal of chromatography, 1987, Jan-09, Volume: 385

    Topics: Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Chromatography, High Pressure Liquid; Chrysenes; Male; Microsomes, Liver; Phenanthrenes; Phenobarbital; Phenols; Rats; Rats, Inbred Strains

1987
[Determination of phenathrene-9,10-epoxidase in the liver microsomes of rats. The effect of induction on the activity of the enzyme].
    Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology, 1986, Volume: 31, Issue:3

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Detergents; Enzyme Induction; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases; Phenanthrenes; Phenobarbital; Polidocanol; Polyethylene Glycols; Rats; Rats, Inbred Strains

1986
Effect of certain drugs and environmental agents on microsomal enzyme systems.
    The Science of the total environment, 1972, Volume: 1, Issue:2

    Topics: Aminopyrine N-Demethylase; Animals; Anisoles; Aspirin; Cytochrome P-450 Enzyme System; DDT; Enzyme Induction; Intestine, Small; Kidney; Lung; Male; Microsomes; Microsomes, Liver; Morphinans; Nitro Compounds; Oxidoreductases, N-Demethylating; Phenacetin; Phenanthrenes; Phenobarbital; Phenytoin; Rats; Transferases; Trifluoperazine

1972
Conversion of naphthalene to trans-naphthalene dihydrodiol: evidence for the presence of a coupled aryl monooxygenase-epoxide hydrase system in hepatic microsomes.
    Biochemical and biophysical research communications, 1972, Feb-25, Volume: 46, Issue:4

    Topics: Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Chlorine; Ethers, Cyclic; Ethylmaleimide; Glutathione; Glycols; Guinea Pigs; Hydrolases; Male; Maleates; Methylcholanthrene; Microsomes, Liver; Naphthalenes; Oxygenases; Phenanthrenes; Phenobarbital

1972
Metabolism of benzo[c]phenanthrene by rat liver microsomes and by a purified monooxygenase system reconstituted with different isozymes of cytochrome P-450.
    Chemico-biological interactions, 1983, Jul-01, Volume: 45, Issue:1

    Topics: Animals; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Phenanthrenes; Phenobarbital; Phenols; Rats; Stereoisomerism

1983
Stereoselective metabolism of the (+)- and (-)-enantiomers of trans-1,2-dihydroxy-1,2-dihydrochrysene to bay-region 1,2-diol-3,4-epoxide diastereomers by rat liver enzymes.
    Molecular pharmacology, 1982, Volume: 22, Issue:1

    Topics: Animals; Chrysenes; Cytochrome P-450 Enzyme System; Epoxy Compounds; In Vitro Techniques; Liver; Male; Methylcholanthrene; Microsomes, Liver; Phenanthrenes; Phenobarbital; Rats; Spectrophotometry, Ultraviolet; Stereoisomerism

1982
Metabolism of chrysene and phenanthrene to bay-region diol epoxides by rat liver enzymes.
    Molecular pharmacology, 1981, Volume: 19, Issue:1

    Topics: Animals; Biotransformation; Chemical Phenomena; Chemistry; Chrysenes; Epoxide Hydrolases; Epoxy Compounds; Ethers, Cyclic; In Vitro Techniques; Liver; Male; Methylcholanthrene; Microsomes, Liver; Molecular Conformation; Phenanthrenes; Phenobarbital; Rats

1981
Metabolism of (-)-trans-(3R, 4R)-dihydroxy-3,4-dihydrochrysene to diol epoxides by liver microsomes.
    Biochemical and biophysical research communications, 1981, Feb-27, Volume: 98, Issue:4

    Topics: Animals; Chemical Phenomena; Chemistry; Chrysenes; Epoxy Compounds; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Phenanthrenes; Phenobarbital; Rats; Stereoisomerism

1981
Assessment of the roles of P-glycoprotein and cytochrome P450 in triptolide-induced liver toxicity in sandwich-cultured rat hepatocyte model.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:12

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; bcl-2-Associated X Protein; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diterpenes; Epoxy Compounds; Hepatocytes; Hydrogen Peroxide; Liver; Male; Phenanthrenes; Phenobarbital; Proto-Oncogene Proteins c-bcl-2; Quercetin; Quinolines; Rats; Rats, Sprague-Dawley; Ritonavir

2013