phenobarbital has been researched along with pentylenetetrazole in 214 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 151 (70.56) | 18.7374 |
| 1990's | 23 (10.75) | 18.2507 |
| 2000's | 21 (9.81) | 29.6817 |
| 2010's | 15 (7.01) | 24.3611 |
| 2020's | 4 (1.87) | 2.80 |
| Authors | Studies |
|---|---|
| Alkskas, IA; Azam, F; Khokra, SL; Prakash, O | 1 |
| Kleinhaus, AL | 1 |
| Luscombe, DK; Nicholls, PJ | 1 |
| Javid, MJ; Stone, WE | 1 |
| Blake, GJ; Gilbert, MB; Raines, A; Richardson, B | 1 |
| Georgiev, VP; Petkova, BP | 1 |
| Costa, E; Guidotti, A; Mao, CC; Suria, A | 1 |
| Ferrendelli, JA; Kinscherf, DA | 1 |
| Jones, DJ; Medina, MA; Palmer, GC; Stavinoha, WB | 1 |
| Browning, RA; Hoffmann, WE; Simonton, RL | 1 |
| Decsi, L; Nagy, J | 1 |
| Fakouhi, T; Zirvi, KA | 1 |
| Kupferberg, HJ; Penry, JK; Schmidt, D; Yonekawa, W | 1 |
| Banerjee, U; Yeoh, PN | 1 |
| Brockman, WH; Strain, GM; Van Meter, WG | 1 |
| Bantutova, I; Koburova, K; Ovcharov, R | 1 |
| Hegerová, E; Koudelková, L; Simůnek, J | 1 |
| Frey, HH; Löscher, W | 1 |
| Gardner, CR; Webster, RA | 2 |
| Bielicki, L; Krieglstein, J | 1 |
| Cole, FR; Nelson, RB | 1 |
| Katagiri, M | 1 |
| Dwivedi, C; Harbison, RD | 1 |
| Przegaliński, E | 1 |
| Desmedt, LK; Janssen, PA; Niemegeers, CJ | 1 |
| Baumel, IP; Dimicco, J; Dionne, R; Gallagher, BB | 1 |
| Barry, H; Sofia, RD; Solomon, TA | 1 |
| Chaplain, RA; Krämer, G | 1 |
| Mares, P; Stanková, L | 1 |
| Bodewei, R; Fischer, W; Satzinger, G | 1 |
| Kostadinova, I; Krustev, A; Millusheva, M; Toreva, D | 1 |
| Alfon, J; Hoffman, A | 1 |
| Hudda, MM; Kim, CK; Pinel, JP; Wong, DJ; Yung, A | 1 |
| Faktorová, M; Kubová, H; Mares, P | 1 |
| Fredow, G; Löscher, W | 1 |
| Fischer, W | 1 |
| Czuczwar, SJ; Kleinrok, Z; Małek, U | 1 |
| File, SE; Wilks, LJ | 1 |
| Alpern, HP; McIntyre, TD | 1 |
| Sedlácek, J | 2 |
| File, SE; Johnston, AL | 1 |
| Danhof, M; Dingemanse, J; van Bree, JB | 1 |
| Levy, G; Walker, JS | 1 |
| Nagatani, T; Sugihara, T; Ueki, S; Yamamoto, T | 1 |
| Aburada, M; Hosoya, E; Iizuka, S; Ishige, A; Matsuzaki, Y; Sakamoto, K; Sekiguchi, K; Sugaya, E | 1 |
| Bender, AS; Hertz, L | 1 |
| Ibba, M; Mennini, T; Testa, R | 1 |
| Lloyd, KG | 1 |
| Hönack, D; Löscher, W; Nolting, B | 1 |
| Hirayama, H; Horibe, M; Kurimoto, T; Machida, N; Shikuma, H; Shoji, S; Wada, S | 1 |
| Buterbaugh, GG; Michelson, HB | 1 |
| Bentley, M; Feely, M; Gent, JP; Haigh, JR | 1 |
| Abed, WT | 1 |
| Bourgeois, BF | 1 |
| Kanai, S; Kitani, K; Masuda, Y; Nokubo, M; Ohta, M; Sato, Y | 1 |
| Levy, G; Wanwimolruk, S | 1 |
| Clark, CR; Lin, CM; Sansom, RT | 1 |
| Chweh, AY; Coleman, JC; Shenoy, AK; Swinyard, EA | 1 |
| Carnel, SB; Lathers, CM; Schraeder, PL | 2 |
| Lasek, R; Müller, M | 1 |
| Gerald, MC; Massey, J; Spadaro, DC | 1 |
| Constantinescu, E; Haţegan, D; Kreindler, A | 1 |
| Gogerty, JH; Iorio, LC; Ryan, EA | 1 |
| Owasoyo, JO; Walker, CA | 1 |
| Killam, EK; Killam, KF; Naquet, R | 1 |
| Barron, BA; Woolley, D | 1 |
| Wilson, WS | 1 |
| De la Torre, JC; Kawanaga, HM; Mullan, S | 1 |
| Millichap, JG | 1 |
| Gillette, JR; Stripp, B | 1 |
| Rosenblum, I; Saelens, JK | 1 |
| Anand, N; Bindra, JS; Garg, CP; Patnaik, GK; Vohra, MM | 1 |
| Baxter, BL | 1 |
| Rümke, CL | 1 |
| Fähndrich, A; Göres, E | 1 |
| Koch, H | 1 |
| Izquierdo, I | 1 |
| Koldaev, VM | 1 |
| Derr, RF; Zieve, L | 1 |
| Adcock, JJ; Gilbert, JC | 1 |
| Kazama, K | 1 |
| Hooker, ML; Vida, JA | 1 |
| Baumel, IP; DiMicco, J; Gallagher, BB; Goico, H | 1 |
| Niner, JM; Pace, DG; Raines, A | 1 |
| Carrano, RA; McCurdy, DH; Neumeyer, JL; Weinhardt, KK | 1 |
| Baxter, MG; Miller, AA; Webster, RA | 1 |
| Frey, HH; Meyer, H | 1 |
| Frey, HH; Kilian, M | 1 |
| Hooker, ML; Samour, CM; Vida, JA | 1 |
| Berry, CA; Faingold, CL | 1 |
| Bennett, EL; Chang Wu, SY; Rosenzweig, MR | 1 |
| Izquierdo, I; Tannhauser, M | 1 |
| Chesher, GB; Jackson, DM | 1 |
| Cely, W; Karler, R; Olsen, DM; Turkanis, SA | 1 |
| Swinyard, EA | 1 |
| Halpern, LM; Ward, AA | 1 |
| Gylys, JA; Hillyard, IW; Robichaud, RC; Sledge, KL | 1 |
| Marcus, RJ; Roberts, E; Simonsen, DG; Winters, WD | 1 |
| Cooke, WJ; Robinson, JD; Weiner, IM | 1 |
| Christensen, JA; Lassen, JB; Lund, J; Squires, RF | 1 |
| Blackburn, WH; Napoli, MD; Wallin, RF | 1 |
| Keyl, AC; Nishie, K; Waiss, AC | 1 |
| Clark, LD; Weinreich, D | 1 |
| Coeugniet, E; Dobrescu, D | 1 |
| Combs, G; Diamond, L; Glasser, AC | 1 |
| Southgate, PJ | 1 |
| Belsky, I; Gertner, D; Zilkha, A | 1 |
| Arai, Y; Gorski, RA | 1 |
| Burba, JV | 1 |
| Burgison, RM; Dietz, AJ | 1 |
| Colley, B; Spehlman, R | 1 |
| Ferngren, H | 1 |
| Hahn, F; Kretzschmar, R; Meyer, HJ | 1 |
| Coldman, MF; Good, W | 1 |
| Kretzschmar, R; Meyer, HJ | 1 |
| Fried, IM; Loev, B; Macko, E | 1 |
| Bartels, E; Rosenberg, P | 1 |
| Geschwind, N; Sherwin, I | 1 |
| King, LJ; Lowry, OH; Passonneau, JV; Venson, V | 1 |
| Sanders, HD | 1 |
| Newman, BL | 1 |
| Rascio, L | 1 |
| Dick, RW; Mitchell, CL | 1 |
| Kosoĭ, MIu | 1 |
| Breuer, H; Fleischhauer, K; Höller, M | 1 |
| Kryzhanovskiĭ, GN; Nikushkin, EV; Shandra, AA | 1 |
| Lajtha, A; Toth, E | 1 |
| Passarelli, F; Sagratella, S; Scotti de Carolis, A | 1 |
| Bourgeois, BF; Dodson, WE; Ferrendelli, JA | 2 |
| Czuczwar, SJ; Kleinrok, Z; Turski, L; Turski, W | 1 |
| Albertson, TE; Joy, RM; Stark, LG | 1 |
| Baldauf, J; Büch, HP; Wolff, I | 1 |
| Angioi, RM; Bonetti, EP; Cumin, R; Haefely, WE; Möhler, H; Pieri, L; Polc, P | 1 |
| Albertson, TE; Lakin, ML; Peterson, SL; Stark, LG; Winters, WD | 1 |
| Albertson, TE; Peterson, SL; Stark, LG | 1 |
| Alberton, TE; Bowyer, JF | 1 |
| Mares, P; Maresová, D | 1 |
| Bastidas Ramírez, BE; García Estrada, J; García López, P; Garzón, P; Navarro Ruíz, A | 1 |
| el-Naser Ossman, AR; el-Sayed Barakat, S | 1 |
| Alfon, J; Hoffman, A; Siegal, T | 1 |
| Alfon, J; Gorodetsky, R; Habib, G; Hoffman, A; Pinto, E | 1 |
| Duburs, G; Germane, SK; Karpova, MN; Klusha, VE; Pankov, OIu | 1 |
| Becker, A; Brosz, M; Grecksch, G | 1 |
| Eid, NM; el-Tawab, HA; Ragab, FA | 1 |
| da Silva, LF; Elisabetsky, E; Pereira, P | 1 |
| Shapovalov, VV; Shapovalova, VO | 1 |
| Czuczwar, SJ; Kleinrok, Z; Klonowski, P; Tutka, P | 1 |
| Gupta, YK; Malhotra, J | 1 |
| Brum, LF; Elisabetsky, E; Souza, DO | 1 |
| Casillass-Ochoa, J; García-Estrada, J; García-López, PM; Garzón-De la Mora, P; Navarro-Ruíz, A; Villanueva-Michel, T; Villarreal-de Puga, LM | 1 |
| Elisabetsky, E; Silva Brum, LF | 1 |
| Reddy, DS; Rogawski, MA | 1 |
| Kohn, H; LeTiran, A; Stables, JP | 1 |
| Bidar, A; Kondziella, D; Sletvold, O; Sonnewald, U; Urfjell, B | 1 |
| Hamann, M; Richter, A | 1 |
| Groenink, L; Maes, RA; Olivier, B; Oosting, RS; Pattij, T; van der Gugten, J | 1 |
| Kishore Gnanasam, S; Leonard, JT; Ramachandran, S; Sivakumar, R | 1 |
| Hammer, J; Kondziella, D; Sletvold, O; Sonnewald, U | 1 |
| BERNAT, P; BRZEK, A; DEDEK, V; ZOUBEK, J | 1 |
| HAHN, F; OBERDORF, A | 1 |
| MAJ, J | 1 |
| BOURGAULT, PC; KARCZMAR, AG; SCUDDER, CL | 1 |
| FRANK, GB; SANDERS, HD | 1 |
| SIGG, EB; WARNER, CL; YEN, HC | 1 |
| KRIVOY, WA; KROEGER, DC; LANE, M | 1 |
| BOTTIROLI, JA; ROSENBERG, FJ | 1 |
| CHUBB, FL; HAJDU, A; KOMLOSSY, J; LEE, CF; MCCOLL, JD | 1 |
| FINK, GB; JUCHAU, MR | 1 |
| CHAREST, MP; DAVIS, MA; GAUDRY, R; HERR, F; THOMAS, RA; WINTHROP, SO | 1 |
| BEGUIN, M; FAMILY, S; FLEURY, C; FROMMEL, E; LEDEBUR, IV | 1 |
| MITCHELL, CL | 1 |
| GREEN, VA | 1 |
| FREY, HH | 1 |
| TEUCHMANN, JK; WIGLUSZ, Z | 1 |
| BASS, P; CHEN, G | 1 |
| KESNER, RP; O'KELLY, LI; THOMAS, GJ | 1 |
| LOEWE, S | 1 |
| El-Helby, AG; Wahab, MH | 1 |
| GOLD, P | 1 |
| Borowicz, KK; Czuczwar, SJ; Luszczki, JJ | 1 |
| Löscher, W; Potschka, H; Rieck, S; Rundfeldt, C; Tipold, A | 1 |
| Meza-Toledo, SE; Mora-Ramírez, EY; Noguerón-Chirinos, JB; Olea-Gómez, A; Peralta-Cruz, J | 1 |
| Alonso, SJ; Castellano, MA; Martín, FA; Navarro, E | 1 |
| Czuczwar, SJ; Luszczki, JJ; Patsalos, PN; Ratnaraj, N | 2 |
| Bhattacharyya, D; Dey, S; Mandal, TK; Manna, S | 1 |
| Liu, X; Yang, H; Yang, J; Yang, Z | 1 |
| Cappelari, SE; da Silva Brum, LF; de Oliveira, PA; Lino, FL; Pereira, P; Picada, JN | 1 |
| Cabrera-Cedillo, F; Cruz-Peinado, C; Lira-Zárate, F; Meza-Toledo, SE; Miñón-López, H; Peralta-Alvarez, B; Peralta-Cruz, J; Robles-Martínez, EL | 1 |
| Andres-Mach, MM; Czuczwar, SJ; Dudra-Jastrzebska, M; Luszczki, JJ; Patsalos, PN; Ratnaraj, N | 1 |
| Jing, X; Liu, X; Wang, G; Wen, T; Xie, L; Xie, S; Yao, D | 1 |
| DE RAMIREZ DE ARELLANO, MI | 1 |
| Andres-Mach, M; Barcicka-Klosowska, B; Czuczwar, SJ; Florek-Luszczki, M; Haratym-Maj, A; Luszczki, JJ | 1 |
| Arai, Y; Higuchi, H; Maeda, S; Miyawaki, T; Shimada, M; Tomoyasu, Y | 1 |
| Ayyad, RR; Elhelby, AA; Zayed, MF | 1 |
| Bankstahl, JP; Bankstahl, M; Bloms-Funke, P; Löscher, W | 1 |
| Hoffmann, K; Löscher, W; Potschka, H; Töllner, K; Twele, F | 1 |
| Brandt, C; Brunhofer, G; Erker, T; Feit, PW; Gabriel, M; Kaila, K; Lindfors, J; Löscher, W; Töllner, K; Töpfer, M | 1 |
| Fleck, J; Jesse, AC; Marafiga, JR; Mello, CF; Rambo, LM; Ribeiro, LR | 1 |
| Abadi, AH; Abdelfattah, MA; Habib, MM | 1 |
| Borowicz, KK; Popławska, M; Wróblewska, D | 1 |
| Fleck, J; Jesse, AC; Marafiga, JR; Mello, CF; Milanesi, LH; Rambo, LM; Temp, FR | 1 |
| Brandt, C; Erker, T; Löscher, W; Schidlitzki, A; Schreppel, P; Töllner, K; Twele, F | 1 |
| Löscher, W; Töllner, K; Twele, F | 1 |
| Blanco, MM; Cinini, SM; Lima, TZ; Mello, LE; Pontes, JC; Queiroz, CM | 1 |
| Barbas, LAL; de Mello, VJ; do Nascimento, JLM; Dos Santos Batista, L; Dos Santos Batista, P; Farias, RAF; Gomes-Leal, W; Hamoy, M; Hutchison, WD; Marcondes, HC; Taylor, JG; Torres, MF | 1 |
| Auer, T; Erker, T; Schreppel, P; Schwarzer, C | 1 |
| Czuczwar, SJ; Raszewski, G; Łukawski, K | 1 |
| Araújo, DB; Azevedo, JEC; Barbas, LAL; da Silva, ALM; Hamoy, AO; Hamoy, M; Lopes, DCF; Lopez, MEC; Mello, VJ; Nascimento, CP; Pereira, RG; Rodrigues, SF; Vieira, LR | 1 |
| Azevedo, JEC; de Araujo, DB; de Mello, VJ; Favacho Lopes, DC; Hamoy, AO; Hamoy, M; Martins Rodrigues, JC; Nascimento, CP; Silva, ALMD; Tiago, ACDS; Vieira, LR | 1 |
5 review(s) available for phenobarbital and pentylenetetrazole
| Article | Year |
|---|---|
New concepts on the mechanism of action of benzodiazepines.
Topics: Animals; Benzodiazepines; Cerebellum; Chlordiazepoxide; Cyclic AMP; Diazepam; gamma-Aminobutyric Acid; Ganglia, Autonomic; Glycine; Humans; Isoniazid; Medulla Oblongata; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Receptors, Drug; Seizures; Sensory Receptor Cells; Spinal Cord; Strychnine; Substantia Nigra | 1975 |
[GABAergic theory of epilepsy].
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Benzodiazepines; Bicuculline; Brain; Dogs; Epilepsy; gamma-Aminobutyric Acid; Humans; Mice; Nerve Endings; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; Receptors, GABA-A; Synapses; Valproic Acid | 1986 |
Relation of laboratory evaluation to clinical effectiveness of antiepileptic drugs.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzazepines; Clinical Trials as Topic; Drug Tolerance; Electroencephalography; Electroshock; Epilepsy; Ethosuximide; Humans; Pentylenetetrazole; Phenobarbital; Phenytoin; Primidone; Seizures; Trimethadione; Urea | 1969 |
[Use of chemical substances in ultrahigh frequency electromagnetic radiation (review of the literature)].
Topics: Animals; Anura; Ascorbic Acid; Atropine; Chlorpromazine; Epinephrine; Ergotamine; Glucose; Humans; Microwaves; Panax; Pentylenetetrazole; Phenobarbital; Plants, Medicinal; Pyridoxine; Rabbits; Radiation Injuries; Radiation Injuries, Experimental; Radiation-Protective Agents; Rats; Strychnine; Tubocurarine; Valerian; Vitamin B Complex | 1972 |
Laboratory evaluation of antiepileptic drugs. Review of laboratory methods.
Topics: Animals; Anticonvulsants; Biological Assay; Brain Injuries; Diagnosis; Electroconvulsive Therapy; Electroshock; Humans; Methionine Sulfoximine; Methods; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Seizures; Strychnine; Thiosemicarbazones; Trimethadione; Urea | 1969 |
1 trial(s) available for phenobarbital and pentylenetetrazole
| Article | Year |
|---|---|
Relation of laboratory evaluation to clinical effectiveness of antiepileptic drugs.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzazepines; Clinical Trials as Topic; Drug Tolerance; Electroencephalography; Electroshock; Epilepsy; Ethosuximide; Humans; Pentylenetetrazole; Phenobarbital; Phenytoin; Primidone; Seizures; Trimethadione; Urea | 1969 |
209 other study(ies) available for phenobarbital and pentylenetetrazole
| Article | Year |
|---|---|
Synthesis of some novel N4-(naphtha[1,2-d]thiazol-2-yl)semicarbazides as potential anticonvulsants.
Topics: Animals; Anticonvulsants; Brain Chemistry; Glutathione Peroxidase; Malondialdehyde; Mice; Motor Activity; Rats; Seizures; Semicarbazides; Structure-Activity Relationship; Superoxide Dismutase | 2009 |
Electrophysiological actions of convulsants and anticonvulsants on neurons of the leech subesophageal ganglion.
Topics: Animals; Bemegride; Ganglia, Autonomic; Leeches; Magnesium; Membrane Potentials; Neurons; Penicillin G; Pentylenetetrazole; Phenobarbital; Strychnine | 1975 |
Proceedings: Potential tolerance to beclamide and related drug interactions.
Topics: Amines; Animals; Anticonvulsants; Benzylamines; Drug Interactions; Drug Tolerance; Female; Microsomes, Liver; Pentobarbital; Pentylenetetrazole; Phenobarbital; Propionates; Rats; Sleep | 1975 |
Benzodiazepines and phenobarbital as antagonists of dissimilar chemical convulsants.
Topics: 3-Mercaptopropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsants; Bicuculline; Chlordiazepoxide; Convulsants; Diazepam; gamma-Aminobutyric Acid; Isoniazid; Male; Mice; Nitrazepam; Pentylenetetrazole; Phenobarbital; Picrotoxin; Therapeutic Equivalency | 1978 |
Differential selectivity of several barbiturates on experimental seizures and neurotoxicity in the mouse.
Topics: Animals; Barbital; Barbiturates; Dose-Response Relationship, Drug; Male; Mice; Neuromuscular Diseases; Pentobarbital; Pentylenetetrazole; Phenobarbital; Seizures; Thiopental | 1979 |
Effect of p-chlorophenylalanine on the central nervous excitability threshold and on the activity of some central depressants.
Topics: Animals; Central Nervous System; Depression, Chemical; Fenclonine; Hypnotics and Sedatives; Injections, Intraperitoneal; Injections, Intravenous; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenylacetates; Picrotoxin; Seizures; Strychnine; Time Factors; Toluene; Urea | 1975 |
Cyclic nucleotides in epileptic brain: effects of pentylenetetrazol on regional cyclic AMP and cyclic GMP levels in vivo.
Topics: Animals; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Cyclic AMP; Cyclic GMP; Ethosuximide; Female; Hippocampus; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Thalamus | 1977 |
Anticonvulsant drug actions on in vitro and in vivo levels of cyclic AMP in the mouse brain.
Topics: Adenosine; Animals; Anticonvulsants; Brain; Carbamazepine; Cerebellum; Cerebral Cortex; Clonazepam; Culture Techniques; Cyclic AMP; Diazepam; Male; Mice; Norepinephrine; Ouabain; Pentylenetetrazole; Phenobarbital; Phenytoin; Potassium; Premedication; Seizures | 1979 |
Changes in seizure susceptibility after intracerebral treatment with 5,7-dihydroxytryptamine: role of serotonergic neurons.
Topics: 5,7-Dihydroxytryptamine; Acetazolamide; Animals; Anticonvulsants; Dihydroxytryptamines; Electroshock; Male; Neurons; Pentylenetetrazole; Phenobarbital; Phenytoin; Raphe Nuclei; Rats; Seizures; Serotonin | 1978 |
Further studies on the site of action of diazepam: anticonvulsant effect in the rabbit.
Topics: Action Potentials; Amygdala; Animals; Anticonvulsants; Diazepam; Electric Stimulation; Electroencephalography; Female; Hippocampus; Male; Pentylenetetrazole; Phenobarbital; Rabbits; Seizures | 1979 |
Synthesis and neuropharmacology of cyclobutanecarbonylureas.
Topics: Animals; Central Nervous System Depressants; Female; Male; Mice; Oxotremorine; Pentylenetetrazole; Phenobarbital; Strychnine; Urea | 1979 |
[Development of tolerance of phenobarbital after administration over several days (author's transl)].
Topics: Animals; Anticonvulsants; Drug Tolerance; Electroshock; Male; Mice; Pentylenetetrazole; Phenobarbital; Time Factors | 1978 |
The temporal dimensions of anticonvulsant action of some newer benzodiazepines against metrazol induced seizures in mice and rats.
Topics: Animals; Benzodiazepines; Clonazepam; Diazepam; Drug Evaluation, Preclinical; Ethosuximide; Female; Flurazepam; Male; Mice; Nitrazepam; Pentylenetetrazole; Phenobarbital; Seizures; Trimethadione | 1977 |
Elevation of seizure thresholds: a comparison of cerebellar stimulation, phenobarbital, and diphenylhydantoin.
Topics: Animals; Cerebellar Cortex; Cerebral Cortex; Electric Stimulation; Electroencephalography; Male; Pentylenetetrazole; Phenobarbital; Phenytoin; Rabbits; Seizures | 1978 |
Changes in the convulsion threshold and in the level of brain biogenic amines in rats chronically treated with phenobarbital or diazepam.
Topics: Animals; Biogenic Amines; Brain Chemistry; Diazepam; Dopamine; Drug Synergism; Male; Norepinephrine; Pentylenetetrazole; Phenobarbital; Rats; Seizures; Serotonin | 1978 |
[Problem of reciprocal influence of drugs in animals].
Topics: Animals; Bemegride; Central Nervous System; Drug Synergism; Mice; Pentylenetetrazole; Phenobarbital; Sulfamethazine | 1976 |
Di-n-propylacetic acid--profile of anticonvulsant activity in mice.
Topics: Animals; Anticonvulsants; Bicuculline; Dose-Response Relationship, Drug; Electroshock; Ethosuximide; Female; Male; Mice; Pentylenetetrazole; Phenobarbital; Picrotoxin; Seizures; Strychnine; Trimethadione; Valerates; Valproic Acid | 1976 |
Convulsant-anticonvulsant interactions on seizure activity and cortical acetylcholine release.
Topics: Acetylcholine; Animals; Anticonvulsants; Bicuculline; Blood Pressure; Cerebral Cortex; Convulsants; Drug Interactions; Electroencephalography; Male; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; Seizures; Time Factors; Trimethadione | 1977 |
The effect of anesthesia on brain mitochondrial hexokinase.
Topics: Anesthesia; Animals; Brain; Halothane; Hexokinase; In Vitro Techniques; Male; Mitochondria; Pentylenetetrazole; Phenobarbital; Rats; Solubility | 1977 |
The convulsive profile of Cicuta douglasii (water hemlock).
Topics: Animals; Anticonvulsants; Convulsants; Electroshock; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Plant Extracts | 1976 |
[Ultrastructural changes of the rat cerebellum due to pentetrazol and phenobarbital administration--in special references to the changes of synaptic vesicles associated with convulsive seizures (author's transl)].
Topics: Animals; Cerebellum; Male; Pentylenetetrazole; Phenobarbital; Rats; Seizures; Synaptic Vesicles | 1976 |
Anticonvulsant activities of delta-8 and delta-9 tetrahydrocannabinol and uridine.
Topics: Animals; Anticonvulsants; Cannabis; Dronabinol; Electroshock; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Plant Extracts; Seizures; Uridine | 1975 |
The role of 5-hydroxytryptamine in the mechanism of action of anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Female; Mice; Pentylenetetrazole; Phenobarbital; Seizures; Serotonin | 1975 |
Anticonvulsive properties of cinnarizine and flunarizine in rats and mice.
Topics: Animals; Anticonvulsants; Cinnarizine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Female; Lethal Dose 50; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Piperazines; Rats; Seizures; Time Factors | 1975 |
Metabolism, distribution and anticonvulsant properties of N,N'- dimethoxymethyl-phenobarbital in the rat.
Topics: Animals; Anticonvulsants; Brain; Chromatography, Thin Layer; Electroshock; Liver; Male; Pentylenetetrazole; Phenobarbital; Rats; Seizures; Time Factors | 1976 |
Anticonvulsant activity of delta9-tetrahydrocannabinol compared with three other drugs.
Topics: Animals; Anticonvulsants; Cannabis; Chlordiazepoxide; Dronabinol; Electroshock; Male; Mice; Nicotine; Pentylenetetrazole; Pharmaceutical Vehicles; Phenobarbital; Phenytoin; Seizures; Strychnine; Time Factors | 1976 |
Metabolic regulations of the rhythmic activity in pacemaker neurons. III. Neutralization of the pentylenetetrazol effect in regularly beating Aplysia neurons by metabolic modifiers.
Topics: Adenosine Triphosphate; Animals; Citrates; Fructosephosphates; Ganglia; Glyceric Acids; Mollusca; Pentobarbital; Pentylenetetrazole; Periodicity; Phenobarbital | 1976 |
Influence of phenobarbital on ECoG phenomena induced by metrazol in rats during ontogenesis.
Topics: Aging; Animals; Cerebral Cortex; Clonazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Electrodes; Electroencephalography; Epilepsy; Ethosuximide; Injections, Intraperitoneal; Male; Pentylenetetrazole; Phenobarbital; Prohibitins; Rats; Rats, Wistar; Valproic Acid | 1992 |
Anticonvulsant and sodium channel blocking effects of ralitoline in different screening models.
Topics: Animals; Anticonvulsants; Brain; Cells, Cultured; Electric Stimulation; Male; Mice; Models, Biological; Motor Activity; Pentylenetetrazole; Phenobarbital; Rats; Rats, Wistar; Seizures; Sodium Channels; Strychnine; Thiazoles | 1992 |
Effects of phenobarbital, carbamazepine and a combination of both on corazol-induced changes in the bioelectric activity of rat brains.
Topics: Animals; Brain; Carbamazepine; Electroencephalography; Epilepsy; Male; Pentylenetetrazole; Phenobarbital; Rats; Rats, Wistar | 1992 |
High-dose methotrexate does not affect the pharmacodynamics of phenobarbital hypnotic action but decreases the central nervous system (CNS) sensitivity to pentylenetetrazol-induced maximal seizures in rats.
Topics: Animals; Brain Chemistry; Central Nervous System; Chromatography, High Pressure Liquid; Glucose; Hypnotics and Sedatives; Infusions, Intravenous; Male; Methotrexate; Pentylenetetrazole; Phenobarbital; Postural Balance; Rats; Reflex; Seizures | 1992 |
Tolerance to the anticonvulsant effects of phenobarbital, trimethadione, and clonazepam in kindled rats: cross tolerance to carbamazepine.
Topics: Amygdala; Animals; Anticonvulsants; Brain; Carbamazepine; Clonazepam; Drug Tolerance; Electrodes, Implanted; Electroshock; Kindling, Neurologic; Male; Pentylenetetrazole; Phenobarbital; Rats; Seizures; Stereotaxic Techniques; Trimethadione | 1992 |
Effect of phenobarbital on motor seizures elicited by picrotoxin and bicuculline in rats.
Topics: Animals; Bicuculline; Male; Pentylenetetrazole; Phenobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1991 |
Effects of pharmacological manipulation of GABAergic neurotransmission in a new mutant hamster model of paroxysmal dystonia.
Topics: Animals; Baclofen; Carbamazepine; Cricetinae; Diazepam; Disease Models, Animal; Dystonia; gamma-Aminobutyric Acid; Mesocricetus; Mutation; Pentylenetetrazole; Phenobarbital; Phenytoin; Synaptic Transmission; Valproic Acid | 1991 |
[Pharmacologic modulation of central noradrenergic mechanisms and the effect of selected substances on the anticonvulsant effect of phenobarbital in the maximal pentylenetetrazole-seizure test (mice)].
Topics: Animals; Anticonvulsants; Drug Synergism; Male; Mice; Norepinephrine; Pentylenetetrazole; Phenobarbital; Seizures; Sympathetic Nervous System | 1991 |
Influence of calcium channel inhibitors upon the anticonvulsant efficacy of common antiepileptics against pentylenetetrazol-induced convulsions in mice.
Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Diltiazem; Drug Therapy, Combination; Ethosuximide; Male; Mice; Nifedipine; Pentylenetetrazole; Phenobarbital; Reference Values; Seizures; Valproic Acid; Verapamil | 1990 |
Changes in seizure threshold and aggression during chronic treatment with three anticonvulsants and on drug withdrawal.
Topics: Aggression; Animals; Anticonvulsants; Lorazepam; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Social Behavior; Substance Withdrawal Syndrome | 1990 |
Patterns of convulsive susceptibility in the long-sleep and short-sleep selected mouse lines.
Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Female; Flumazenil; Male; Mice; Pentylenetetrazole; Phenobarbital; Reaction Time; Seizures; Sleep | 1989 |
Are spontaneous activity and supraspinal control co-responsible for functional development of the generator of embryonic motility?
Topics: Animals; Central Nervous System; Chick Embryo; gamma-Aminobutyric Acid; Motor Activity; Motor Neurons; Pentylenetetrazole; Phenobarbital | 1989 |
Sodium phenobarbitone reverses the anxiogenic effects of compounds acting at three different central sites.
Topics: Animals; Anxiety; Appetite Depressants; Carbolines; Exploratory Behavior; Male; Pentylenetetrazole; Phenobarbital; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, GABA-A; Social Behavior; Yohimbine | 1989 |
Pharmacokinetic modeling of the anticonvulsant action of phenobarbital in rats.
Topics: Animals; Dose-Response Relationship, Drug; Female; Models, Biological; Pentylenetetrazole; Phenobarbital; Rats; Rats, Inbred Strains; Seizures | 1989 |
Kinetics of drug action in disease states. XXXIV. Effect of experimental thyroid disorders on the pharmacodynamics of phenobarbital, ethanol and pentylenetetrazol.
Topics: Animals; Dose-Response Relationship, Drug; Ethanol; Female; Pentylenetetrazole; Phenobarbital; Rats; Rats, Inbred Lew; Thyroid Diseases; Thyroxine | 1989 |
The effect of agonists at the GABA-benzodiazepine-receptor-complex on the proconflict effect induced by beta-CCM and pentetrazol in rats.
Topics: Aminooxyacetic Acid; Animals; Azabicyclo Compounds; Carbolines; Conflict, Psychological; Convulsants; Diazepam; Flumazenil; Hypnotics and Sedatives; Male; Pentylenetetrazole; Phenobarbital; Piperazines; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
Effect of anticonvulsants on pentylenetetrazol-induced power spectrum changes in electroencephalograms in rats.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Cyclic AMP; Electroencephalography; Ethosuximide; Male; Pentylenetetrazole; Phenobarbital; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1987 |
Evidence for involvement of the astrocytic benzodiazepine receptor in the mechanism of action of convulsant and anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Astrocytes; Barbiturates; Benzodiazepinones; Brain; Carbamazepine; Cells, Cultured; Convulsants; Diazepam; Ethosuximide; Mice; Neurons; Pentylenetetrazole; Phenobarbital; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Trimethadione; Valproic Acid | 1988 |
Consequences of chronic phenobarbital blockade of spontaneous motility in chick embryos for the development of central motor output activity.
Topics: Animals; Bicuculline; Central Nervous System; Chick Embryo; gamma-Aminobutyric Acid; Motor Activity; Oxazepam; Pentylenetetrazole; Phenobarbital; Strychnine | 1988 |
Enhancement of diazepam activities induced by denzimol in mice.
Topics: Animals; Anticonvulsants; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Imidazoles; Male; Mice; Mice, Inbred Strains; Pentylenetetrazole; Phenobarbital; Receptors, GABA-A; Time Factors | 1985 |
Evaluation of CPP, a selective NMDA antagonist, in various rodent models of epilepsy. Comparison with other NMDA antagonists, and with diazepam and phenobarbital.
Topics: Amygdala; Animals; Anticonvulsants; Aspartic Acid; Diazepam; Electroshock; Epilepsy; Female; Gerbillinae; Kindling, Neurologic; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Phenobarbital; Piperazines; Psychomotor Performance; Rats; Time Factors | 1988 |
Antiepileptic effects of globulin-N, an intact human immunoglobulin and its tissue-distribution in kindled cats.
Topics: Amygdala; Animals; Anticonvulsants; Autoradiography; Cats; Drug Combinations; Epilepsy; Half-Life; Immunochemistry; Immunoglobulin A; Immunoglobulin G; Immunoglobulins, Intravenous; Kindling, Neurologic; Ovum; Pentylenetetrazole; Phenobarbital; Phenytoin; Time Factors; Tissue Distribution | 1986 |
Anticonvulsant properties of phencyclidine and ketamine.
Topics: Animals; Anticonvulsants; Hippocampus; Ketamine; Kindling, Neurologic; Mice; Mice, Inbred ICR; Pentylenetetrazole; Phencyclidine; Phenobarbital; Seizures | 1986 |
Benzodiazepine cross-tolerance in mice extends to sodium valproate.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Clobazam; Clonazepam; Diazepam; Drug Tolerance; Lorazepam; Male; Mice; Pentylenetetrazole; Phenobarbital; Valproic Acid | 1986 |
A possible role for spinal noradrenaline in the mechanisms of 6-hydroxydopamine against pentylenetetrazol induced convulsions in rats.
Topics: Animals; Female; Hydroxydopamines; Male; Norepinephrine; Oxidopamine; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Spinal Cord | 1988 |
Anticonvulsant potency and neurotoxicity of valproate alone and in combination with carbamazepine or phenobarbital.
Topics: Animals; Brain; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Electroshock; Female; Mice; Mice, Inbred ICR; Neurotoxins; Pentylenetetrazole; Phenobarbital; Seizures; Valproic Acid | 1988 |
The neurotoxicity of phenobarbital and its effect in preventing pentylenetetrazole-induced maximal seizure in aging mice.
Topics: Administration, Oral; Aging; Animals; Drug Tolerance; Female; Injections, Intraperitoneal; Mice; Pentylenetetrazole; Phenobarbital; Seizures | 1988 |
Kinetics of drug action in disease states. XX. Effects of acute starvation on the pharmacodynamics of phenobarbital, ethanol and pentylenetetrazol in rats and effects of refeeding and diet composition.
Topics: Animals; Blood Proteins; Body Weight; Central Nervous System; Diet; Dietary Carbohydrates; Dietary Proteins; Ethanol; Food; Kinetics; Male; Pentylenetetrazole; Phenobarbital; Protein Binding; Rats; Rats, Inbred Strains; Starvation | 1987 |
Anticonvulsant activity of 2- and 3-aminobenzanilides.
Topics: Anilides; Aniline Compounds; Animals; Anticonvulsants; Electroshock; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures | 1986 |
An analysis of the in vivo interactions between chemical convulsants and anticonvulsants.
Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Mice; Pentylenetetrazole; Phenobarbital; Picrotoxin; Valproic Acid | 1985 |
Effect of phenobarbital pretreatment on cardiac neural discharge and pentylenetetrazol-induced epileptogenic activity in the cat.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Dose-Response Relationship, Drug; Electrocardiography; Electroencephalography; Epilepsy; Heart; Heart Rate; Pentylenetetrazole; Phenobarbital; Sympathetic Nervous System; Vagus Nerve | 1985 |
[The anticonvulsant action of propranolol in pentylenetetrazole-induced convulsions].
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Ethosuximide; Male; Mice; Pentylenetetrazole; Phenobarbital; Propranolol | 1985 |
Comparative convulsant activity of various penicillins after intracerebral injection in mice.
Topics: Ampicillin; Animals; Cephaloridine; Drug Synergism; Hydrogen-Ion Concentration; Injections; Male; Methicillin; Mice; Penicillin G; Penicillin V; Penicillinase; Penicillins; Pentylenetetrazole; Phenobarbital; Phenytoin; Potassium; Seizures; Sodium | 1973 |
Effects of convulsant and anticonvulsant drugs on the activity of some enzymes in the rat brain.
Topics: Animals; Anticonvulsants; Brain; Central Nervous System Stimulants; Electron Transport Complex IV; Monoamine Oxidase; Pentylenetetrazole; Phenobarbital; Rats; Seizures; Strychnine; Transaminases | 1973 |
Anticonvulsant testing with a new analeptic convulsant: N-sulfamoyl-hexahydro-azepine (Sah 41-178).
Topics: Acetamides; Animals; Anticonvulsants; Azepines; Central Nervous System Stimulants; Chlordiazepoxide; Chlorpromazine; Diazepam; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Glutethimide; Haloperidol; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Strychnine; Sulfonamides; Trimethadione | 1973 |
The influence of serotonin, GABA and DL-dopa on the circadian rhythm in the toxicity of picrotoxin, pentylenetetrazol and phenobarbital in mice.
Topics: Aminobutyrates; Animals; Circadian Rhythm; Dihydroxyphenylalanine; gamma-Aminobutyric Acid; Lethal Dose 50; Male; Mice; Pentylenetetrazole; Phenobarbital; Picrotoxin; Serotonin; Time Factors | 1974 |
An animal model of light sensitive epilepsy.
Topics: Adaptation, Physiological; Animals; Anticonvulsants; Cerebral Cortex; Chlorpromazine; Diazepam; Electroencephalography; Electromyography; Electrophysiology; Evoked Potentials; Eye Movements; Female; Haplorhini; Light; Male; Noise; Pentylenetetrazole; Phenobarbital; Photosensitivity Disorders; Seizures; Sleep; Trimethadione | 1967 |
Hippocampal responses evoked by stimulation of the prepyriform cortex in the rat.
Topics: Animals; Cerebral Cortex; Consciousness; Electric Stimulation; Electrophysiology; Evoked Potentials; Female; Hippocampus; Limbic System; Male; Pentylenetetrazole; Phenobarbital; Rats; Sleep; Wakefulness | 1968 |
The effects of phenobarbitone, leptazol, dexamphetamine, iproniazid, imipramine, LSD, chlorpromazine, reserpine and hydroxyzine on the in vivo levels of adenine nucleotides and phosphocreatine in the rat brain.
Topics: Adenine Nucleotides; Adenosine Triphosphatases; Animals; Brain Chemistry; Chlorpromazine; Dextroamphetamine; Hydroxyzine; Imipramine; Iproniazid; Lysergic Acid Diethylamide; Male; Pentylenetetrazole; Phenobarbital; Phosphocreatine; Rats; Reserpine | 1969 |
Seizure susceptibility after manipulation of brain serotonin.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood-Brain Barrier; Brain; Drug Antagonism; Fenclonine; Hydrazines; Male; Pentylenetetrazole; Phenobarbital; Rats; Seizures; Serotonin | 1970 |
Role of drug metabolism in drug research and development: factors affecting metabolism of drugs and their pharmacological and toxicological activity.
Topics: Animals; Benzene Derivatives; Benzopyrenes; Cortisone; Cytochrome c Group; Cytochrome P-450 Enzyme System; Dealkylation; Diazepam; Female; Guinea Pigs; Hexobarbital; Hydroxylation; Male; Methylcholanthrene; Mice; Microsomes, Liver; Morphine; Oxidoreductases; Pentylenetetrazole; Pharmaceutical Preparations; Phenobarbital; Rats; Research; Sleep; Spironolactone | 1972 |
The anticonvulsant activity of triethylcholine in cats.
Topics: Animals; Anticonvulsants; Cats; Choline; Female; Male; Pentylenetetrazole; Phenobarbital; Seizures | 1966 |
Compounds acting on the central nervous system. IV. 4-substituted 2,3-polymethylenequinolines.
Topics: Aminobutyrates; Analgesics; Anesthetics, Local; Animals; Cats; Central Nervous System Stimulants; Chemistry, Organic; Cholinesterase Inhibitors; Drug Antagonism; Guinea Pigs; Mice; Morphine; Nikethamide; Organic Chemistry Phenomena; Pentobarbital; Pentylenetetrazole; Phenobarbital; Quinolines; Rabbits; Rats; Respiratory System; Thiopental | 1966 |
The effect of selected drugs on the "emotional" behavior elicited via hypothalamic stimulation.
Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Cats; Chlorpromazine; Depression, Chemical; Electric Stimulation; Emotions; Hypothalamus; Imipramine; Meprobamate; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Pregnanediones; Reserpine; Scopolamine; Stimulation, Chemical; Strychnine; Tremorine | 1968 |
Increased susceptibility of mice to seizures after some anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Bemegride; Central Nervous System Stimulants; Drug Synergism; Electroshock; Ethionine; Female; Hydantoins; Male; Methods; Mice; Oxazines; Pentylenetetrazole; Phenobarbital; Phenytoin; Primidone; Rats; Seizures; Trimethadione | 1967 |
[Convulsive and anticonvulsive effects of aliphatic and alicyclic sulfonamides].
Topics: Animals; Anticonvulsants; Blood Glucose; Carbonic Anhydrases; Central Nervous System; Central Nervous System Stimulants; Ligases; Male; Mice; Pentylenetetrazole; Phenobarbital; Rats; Seizures; Strychnine; Sulfonamides | 1968 |
[Germination and growth inhibitory effect of thalidomide and different analeptics on embryos of Lepidium sativum].
Topics: Aminobutyrates; Caffeine; Camphor; Carbonates; Central Nervous System Stimulants; Depression, Chemical; Ephedrine; Ethanolamines; Nikethamide; Nitrates; Pentylenetetrazole; Phenobarbital; Seeds; Sodium; Strychnine; Sympathomimetics; Thalidomide | 1969 |
Effect on pseudoconditioning of drugs with known central nervous activity.
Topics: Amobarbital; Animals; Avoidance Learning; Behavior, Animal; Caffeine; Cannabis; Chlorpromazine; Conditioning, Psychological; Depression, Chemical; Diazepam; Dibenzylchlorethamine; Female; Meprobamate; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Rats; Stimulation, Chemical; Strychnine; Trimethadione | 1974 |
Adenylate energy charge: relation to guanylate energy charge and the adenylate kinase equilibrium constant.
Topics: Adenine Nucleotides; Adenosine Monophosphate; Ammonia; Animal Nutritional Physiological Phenomena; Animals; Brain; Coma; Energy Transfer; Ethyl Ethers; Fasting; Guanine Nucleotides; Insulin Coma; Magnesium; Male; Mice; Pentylenetetrazole; Phenobarbital; Phosphotransferases; Rats; Shock | 1972 |
Proceedings: Effects of phenobarbitone and leptazol on rat brain lysosomes.
Topics: Acid Phosphatase; Animals; Brain; Cerebral Cortex; Lysosomes; Male; Mitochondria; Pentylenetetrazole; Phenobarbital; Rats | 1972 |
[Effects of various pharmacological agents on neocortical seizure activities in the rabbit].
Topics: Aminobutyrates; Animals; Cerebral Cortex; Cocaine; Electric Stimulation; Electroencephalography; Evoked Potentials; Lidocaine; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Rabbits; Strychnine | 1972 |
Anticonvulsants. 3. Phenobarbital and mephobarbital derivatives.
Topics: Animals; Anticonvulsants; Barbiturates; Chemical Phenomena; Chemistry; Electroshock; Hypnotics and Sedatives; Male; Mephobarbital; Methods; Mice; Pentylenetetrazole; Phenobarbital; Seizures; Time Factors | 1973 |
Metabolism and anticonvulsant properties of primidone in the rat.
Topics: Amides; Animals; Anticonvulsants; Brain Chemistry; Chromatography, Gas; Electroshock; Male; Malonates; Pentylenetetrazole; Phenobarbital; Primidone; Rats; Seizures; Time Factors | 1973 |
A comparison of the anticonvulsant, neurotoxic and lethal effects of diphenylbarbituric acid, phenobarbital and diphenylhydantoin in the mouse.
Topics: Animals; Anticonvulsants; Barbiturates; Dose-Response Relationship, Drug; Electroshock; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Neurologic Manifestations; Pentylenetetrazole; Phenobarbital; Phenytoin; Reflex; Seizures | 1973 |
Isoquinolines. 3. 3-Aminoisoquinoline derivatives with central nervous system depressant activity.
Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents; Anticonvulsants; Behavior, Animal; Blood Pressure; Cats; Central Nervous System; Depression, Chemical; Electroshock; Heart Rate; Isoquinolines; Mice; Motor Activity; Pentylenetetrazole; Phenobarbital; Phenytoin; Structure-Activity Relationship; Strychnine | 1973 |
The effect of some anticonvulsant drugs on leptazol and bicuculline induced acetylcholine efflux from rat cerebral cortex.
Topics: Acetylcholine; Alkaloids; Animals; Anticonvulsants; Cerebral Cortex; Dioxoles; Dose-Response Relationship, Drug; Electroencephalography; Isoquinolines; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; Seizures; Trimethadione | 1973 |
Some studies on the convulsant action of folic acid.
Topics: Alkaloids; Animals; Auditory Threshold; Cerebral Ventricles; Dioxoles; Electroshock; Folic Acid; Folic Acid Antagonists; Glutamates; Injections; Injections, Intravenous; Isoquinolines; Mice; Ouabain; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Seizures; Strychnine | 1973 |
Dependence of anticonvulsant drug action on central monoamines.
Topics: Animals; Anticonvulsants; Dopamine; Drug Interactions; Electroshock; Ethosuximide; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Norepinephrine; Pentylenetetrazole; Phenobarbital; Phenytoin; Receptors, Drug; Seizures; Serotonin; Time Factors | 1973 |
Thresholds for electro- and chemoconvulsions in mice after termination of treatment with phenobarbital.
Topics: Animals; Anticonvulsants; Differential Threshold; Dose-Response Relationship, Drug; Electroshock; Female; Male; Mice; Mice, Inbred Strains; Pentylenetetrazole; Phenobarbital; Seizures; Statistics as Topic; Time Factors | 1973 |
Anticonvulsants. 4. Metharbital and phenobarbital derivatives.
Topics: Animals; Anticonvulsants; Barbiturates; Electroshock; Lethal Dose 50; Male; Mice; Pentylenetetrazole; Phenobarbital; Seizures | 1973 |
Quantitative evaluation of the pentylenetetrazol-anticonvulsant interaction on the EEG of the cat.
Topics: Animals; Anticonvulsants; Cats; Cerebral Cortex; Computers; Drug Interactions; Electroencephalography; Hippocampus; Pentylenetetrazole; Phenobarbital; Phenytoin; Reticular Formation; Thalamus; Time Factors; Trimethadione | 1973 |
Excitant and depressant drugs modulate effects of environment on brain weight and cholinesterases.
Topics: Acetylcholinesterase; Age Factors; Animals; Brain; Brain Damage, Chronic; Cholinesterases; Dextroamphetamine; Dose-Response Relationship, Drug; Environment; Male; Methamphetamine; Organ Size; Pentylenetetrazole; Phenobarbital; Rats; Strychnine; Time Factors | 1973 |
Effect of seizures and anticonvulsant agents on hippocampal RNA concentration.
Topics: Anesthesia, General; Animals; Anticonvulsants; Cannabis; Cerebral Cortex; Depression, Chemical; Electric Stimulation; Electroshock; Glucose; Hippocampus; Hyponatremia; Male; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; RNA; Seizures; Time Factors; Trimethadione; Urethane | 1974 |
Anticonvulsant effects of cannabinoids in mice: drug interactions within cannabinoids and cannabinoid interactions with phenytoin.
Topics: Animals; Cannabis; Depression, Chemical; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Electroshock; Herb-Drug Interactions; Injections, Intraperitoneal; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Phytotherapy; Seizures; Stimulation, Chemical | 1974 |
Anticonvulsant properties of cannabidiol.
Topics: Animals; Anticonvulsants; Body Temperature; Cannabis; Cold Temperature; Dronabinol; Drug Interactions; Drug Synergism; Electroshock; Hindlimb; Male; Mice; Mice, Inbred ICR; Pentylenetetrazole; Phenobarbital; Phenytoin; Temperature; Time Factors | 1974 |
The hyperexcitable neuron as a model for the laboratory analysis of anticonvulsant drugs.
Topics: Acetazolamide; Action Potentials; Aluminum; Animals; Behavior, Animal; Cats; Cerebral Cortex; Electroencephalography; Haplorhini; Hydroxides; Models, Biological; Neurons; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Time Factors; Trimethadione | 1969 |
The pharmacology of prazepam. A new benzodiazepine derivative.
Topics: Aggression; Animals; Avoidance Learning; Behavior, Animal; Benzazepines; Cats; Chlordiazepoxide; Diazepam; Dogs; Electroshock; Escape Reaction; Female; Haplorhini; Humans; Male; Meprobamate; Mice; Motor Activity; Muscle Contraction; Muscle, Smooth; Pentylenetetrazole; Phenobarbital; Rats; Reflex; Seizures; Strychnine; Time Perception; Tranquilizing Agents | 1970 |
Neuropharmacological studies of imidazole-4-acetic acid actions in the mouse and rat.
Topics: Acetates; Animals; Ataxia; Behavior; Caffeine; Catalepsy; Central Nervous System; Drug Interactions; Drug Synergism; Electroencephalography; Humans; Hydroxybutyrates; Imidazoles; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Motor Activity; Pentylenetetrazole; Phenobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Sleep; Stimulation, Chemical; Strychnine; Time Factors | 1971 |
Factors influencing 45 Ca metabolism in brain and other organs in vivo.
Topics: Animals; Brain; Calcium; Calcium Isotopes; Centrifugation, Density Gradient; Male; Mitochondria; Mitochondria, Liver; Morphine; Myelin Sheath; Neurons; Pentylenetetrazole; Phenobarbital; Rats; Reserpine; Synaptic Vesicles | 1971 |
Pharmacological and biochemical studies on 2-amino-4-phenylsulphonylbenzenesulphonamide (NSD 3004): a new sulphonamide with anticonvulsant and carbonic anhydrase inhibitory properties.
Topics: Animals; Anticonvulsants; Carbonic Anhydrase Inhibitors; Diuresis; Electroshock; Enzyme Activation; Lethal Dose 50; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; Seizures; Strychnine; Sulfonamides | 1971 |
Pharmacologic interactions of albutoin with other anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Drug Synergism; Electroshock; Hydantoins; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Trimethadione | 1970 |
Pharmacology of alkyl and hydroxyalkylpyrazines.
Topics: Animals; Anticonvulsants; Central Nervous System; Glucose; Hypnotics and Sedatives; Imidazoles; Male; Mice; Pentylenetetrazole; Phenobarbital; Pyrazines; Reflex; Seizures | 1970 |
Anticonvulsant drugs and self-stimulation rates in rats.
Topics: Acetazolamide; Animals; Chlordiazepoxide; Electrodes; Male; Meprobamate; Pentobarbital; Pentylenetetrazole; Phenobarbital; Phenytoin; Placebos; Rats; Seizures; Self Stimulation | 1970 |
[Anticonvulsant action of imipramine and imitriptyline associated with phenobarbital, phenytoin and diazepam].
Topics: Amitriptyline; Animals; Anticonvulsants; Diazepam; Electroshock; Imipramine; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures | 1970 |
Synthesis and anticonvulsant activity of substituted 2-thioquinazolin-4-ones. I. Preliminary studies.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry; Electroshock; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Quinazolines; Seizures | 1971 |
A comparison of the anticonvulsant properties of 2-diethylaminopento-4-ynoyl-2',6'-xylidide (WY 21745) with lignocaine, phenytoin, phenobarbitone and trimethadione.
Topics: Anesthetics, Local; Animals; Anticonvulsants; Drug Antagonism; Electroshock; Lethal Dose 50; Lidocaine; Mice; Oxazoles; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Trimethadione | 1971 |
Silicon-containing barbiturates.
Topics: Animals; Barbiturates; Behavior, Animal; Electroshock; Hydantoins; Male; Methods; Mice; Pentylenetetrazole; Phenobarbital; Propylene Glycols; Silicon; Sulfur | 1968 |
Protection against the neural organizing effect of exogenous androgen in the neonatal female rat.
Topics: Animals; Animals, Newborn; Body Weight; Chlorpromazine; Desoxycorticosterone; Female; Hypothalamus; Infertility, Female; Organ Size; Ovary; Pentobarbital; Pentylenetetrazole; Phenobarbital; Pregnanes; Progesterone; Rats; Reserpine; Testosterone; Uterus | 1968 |
Influence of several drugs on the in vivo and in vitro activity of mammalian hepatic azo-reductase.
Topics: Animals; Caffeine; Guanethidine; Guinea Pigs; In Vitro Techniques; Iproniazid; Isoniazid; Liver; Nitrofurantoin; Oxidoreductases; Pentylenetetrazole; Phenobarbital; Phenylbutazone; Phenytoin; Rabbits; Rats; Sulfinpyrazone; Sulfonic Acids; Trimethadione | 1968 |
The hypnotic properties of 8-ethylthio-6-thiotheophylline sodium.
Topics: Amphetamine; Animals; Caffeine; Chloral Hydrate; Chlorpromazine; Dogs; Drug Synergism; Hexobarbital; Hypnotics and Sedatives; Male; Meprobamate; Methylphenidate; Mice; Morphine; Nalorphine; Nikethamide; Pentobarbital; Pentylenetetrazole; Phenobarbital; Rabbits; Rats; Reserpine; Sleep; Theophylline; Thiopental | 1968 |
Effect of diazepam (Valium) on experimental seizures in unanesthetized cat.
Topics: Animals; Cats; Cerebral Cortex; Coma; Diazepam; Electroencephalography; Light; Pentylenetetrazole; Phenobarbital; Seizures | 1968 |
Further studies on chemically induced siezures and their antagonism by anticonvulsants during postnatal development in the mouse.
Topics: Animals; Animals, Newborn; Anticonvulsants; Brain; Mice; Pentylenetetrazole; Phenobarbital; Picrotoxin; Seizures; Trimethadione | 1968 |
[On the inflence of fluid volume on the efficacy of bemegride, Pentetrazole and picrotoxin in phenobarbital poisoning].
Topics: Animals; Bemegride; Mice; Pentylenetetrazole; Pharmaceutical Vehicles; Phenobarbital; Picrotoxin; Seizures; Sodium Chloride; Solutions; Suspensions | 1968 |
The hydrational effect of leptazol and its theoretical connection with glucose deficiency in the haemolysis of rabbit erythrocytes.
Topics: Animals; Barbiturates; Blood Glucose; Brain; Erythrocytes; Glucose; Hemolysis; Malonates; Pentylenetetrazole; Phenobarbital; Rabbits; Seizures | 1969 |
[Comparative studies on the anticonvulsant activity of the pyrone compounds of Piper methysticum Forst].
Topics: Animals; Anticonvulsants; Injections, Intraperitoneal; Injections, Intravenous; Intestinal Absorption; Male; Mephenesin; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Plant Extracts; Plants; Procaine; Pyrans; Reserpine; Shock; Time Factors | 1969 |
Malonamic esters. A new class of sedative-tranquilizers.
Topics: Animals; Chemical Phenomena; Chemistry; Electroshock; Glutethimide; Hypnotics and Sedatives; Liver; Malonates; Meprobamate; Mice; Microsomes; Motor Activity; Pentylenetetrazole; Phenobarbital; Rats; Strychnine; Tranquilizing Agents | 1969 |
Drug effects on the spontaneous electrical activity of the squid giant axon.
Topics: Acetylcholine; Action Potentials; Animals; Anticonvulsants; Atropine; Axons; Barbiturates; Bromides; Chloroform; Chlorpheniramine; Chlorpromazine; Curare; Dopamine; Electrophysiology; Ethanol; Ethers; Evoked Potentials; Hydantoins; Mollusca; Muscles; Nortropanes; Parasympatholytics; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Procaine; Serotonin; Strychnine; Tetracaine; Tremorine; Trihexyphenidyl; Trimethadione | 1967 |
Language-induced epilepsy.
Topics: Electroencephalography; Epilepsy; Ethosuximide; Humans; Male; Middle Aged; Movement Disorders; Pentylenetetrazole; Phenobarbital; Reading; Speech; Speech Disorders; Unconsciousness; Writing | 1967 |
Effects of convulsants on energy reserves in the cerebral cortex.
Topics: Animals; Centrifugation; Cerebral Cortex; Chlorpromazine; Electric Stimulation; Electroshock; Freezing; Glucose; Glycogen; Hypoxia; Insulin; Lactates; Male; Mice; Pentylenetetrazole; Phenobarbital; Phosphocreatine; Secobarbital; Seizures; Stress, Physiological | 1967 |
A comparison of the convulsant activity of procaine and pentylenetetrazol.
Topics: Animals; Anticonvulsants; Chlorpromazine; Dibenzylchlorethamine; Female; Hydroxybutyrates; Mice; Pentobarbital; Pentylenetetrazole; Phenobarbital; Phenytoin; Procaine; Reflex; Reserpine; Seizures | 1967 |
EEG correlates of self-stimulation.
Topics: Animals; Behavior, Animal; Electroencephalography; Male; Pentylenetetrazole; Phenobarbital; Rats; Self Stimulation | 1967 |
[Adrenal cortex and chemical shock: experiments in mice].
Topics: Adrenal Glands; Animals; Mice; Pentylenetetrazole; Phenobarbital; Shock | 1967 |
A comparison of the anticonvulsant properties of l-propylhexedrine, phenobarbital and a salt-like complex of l-propylhexedrine and phenobarbital in mice and rats.
Topics: Animals; Anticonvulsants; Barbiturates; Behavior, Animal; Electroshock; Male; Mice; Pentylenetetrazole; Phenobarbital; Rats; Seizures; Sympathomimetics | 1967 |
[Anticonvulsant action of di-N-propylacetate combined with benzodiazepines, phenobarbital and phenytoin].
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Diazepam; Drug Therapy, Combination; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Semicarbazides; Valproic Acid | 1981 |
An improved method for perfusion of the isolated brain of the rat-influence of perfusion conditions and application of analeptic and anticonvulsant drugs.
Topics: Adenosine Triphosphate; Animals; Anticonvulsants; Brain; Central Nervous System Stimulants; Lactates; Lactic Acid; Male; Pentylenetetrazole; Perfusion; Phenobarbital; Primidone; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Seizures | 1983 |
[Antiepileptic effects of complex therapy with vitamins and anticonvulsant preparations (experimental findings)].
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Drug Therapy, Combination; gamma-Aminobutyric Acid; Mice; Niacinamide; Pantothenic Acid; Pentylenetetrazole; Phenobarbital; Pyridoxal Phosphate; Seizures; Vitamin E; Vitamins | 1982 |
Glycine potentiates the action of some anticonvulsant drugs in some seizure models.
Topics: 3-Mercaptopropionic Acid; Acoustic Stimulation; Animals; Anticonvulsants; Disease Models, Animal; Drug Synergism; Glycine; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1984 |
An EEG investigation on the effects of phencyclidine on pentylentetrazol convulsions in rats and rabbits.
Topics: Animals; Electroencephalography; Male; Pentylenetetrazole; Phencyclidine; Phenobarbital; Rabbits; Rats; Rats, Inbred Strains; Seizures; Species Specificity; Trimethadione | 1983 |
Primidone, phenobarbital, and PEMA: I. Seizure protection, neurotoxicity, and therapeutic index of individual compounds in mice.
Topics: Animals; Bicuculline; Brain; Brain Chemistry; Electroshock; Female; Malonates; Mice; Mice, Inbred Strains; Pentylenetetrazole; Phenobarbital; Phenylethylmalonamide; Primidone; Seizures | 1983 |
Primidone, phenobarbital, and PEMA: II. Seizure protection, neurotoxicity, and therapeutic index of varying combinations in mice.
Topics: Animals; Brain; Brain Chemistry; Drug Synergism; Drug Therapy, Combination; Electroshock; Female; Malonates; Mice; Mice, Inbred Strains; Pentylenetetrazole; Phenobarbital; Phenylethylmalonamide; Primidone; Seizures | 1983 |
Neural mechanisms in cardiac arrhythmias associated with epileptogenic activity: the effect of phenobarbital in the cat.
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Blood Pressure; Cats; Disease Models, Animal; Electrocardiography; Electroencephalography; Epilepsy; Heart; Heart Rate; Lung; Pentylenetetrazole; Phenobarbital | 1984 |
Effects of some antiepileptic drugs in pentetrazol-induced convulsions in mice lesioned with kainic acid.
Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Diazepam; Dose-Response Relationship, Drug; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Mice; Pentylenetetrazole; Phenobarbital; Pyrrolidines; Seizures; Succinimides; Trimethadione; Valproic Acid | 1981 |
The effects of doxapram, diazepam, phenobarbital and pentylenetetrazol on suprathreshold and threshold stimulations in amygdaloid kindled rats.
Topics: Amygdala; Animals; Diazepam; Doxapram; Kindling, Neurologic; Male; Pentylenetetrazole; Phenobarbital; Rats; Rats, Inbred Strains; Seizures | 1983 |
[Drug distribution during convulsive seizure in comparison with narcosis].
Topics: Adipose Tissue; Animals; Antipyrine; Brain; Female; Liver; Pentylenetetrazole; Phenobarbital; Rats; Seizures; Spleen | 1980 |
Caffeine antagonizes several central effects of diazepam.
Topics: Aggression; Animals; Caffeine; Cats; Central Nervous System; Conflict, Psychological; Diazepam; Humans; Hypothalamus; Muscle Tonus; Pentylenetetrazole; Phenobarbital; Spinal Cord | 1981 |
The anticonvulsant properties of melatonin on kindled seizures in rats.
Topics: Amygdala; Animals; Anticonvulsants; Diazepam; Electric Stimulation; Male; Melatonin; Naloxone; Pentylenetetrazole; Phenobarbital; Rats; Seizures | 1981 |
The anticonvulsant effects of diazepam and phenobarbital in prekindled and kindled seizures in rats.
Topics: Amygdala; Animals; Anticonvulsants; Diazepam; Electric Stimulation; Male; Pentylenetetrazole; Phenobarbital; Rats; Seizures | 1981 |
The anticonvulsant effects of diazepam and phenobarbital in prekindled and kindled cortical seizures.
Topics: Amygdala; Animals; Anticonvulsants; Cerebral Cortex; Diazepam; Disease Models, Animal; Epilepsy; Male; Pentylenetetrazole; Phenobarbital; Rats; Rats, Inbred Strains | 1981 |
[Effect of phenobarbital on metrazol convulsions during ontogenesis of rats (author's transl)].
Topics: Age Factors; Animals; Male; Pentylenetetrazole; Phenobarbital; Rats; Seizures | 1980 |
Anticonvulsant activity of Casimiroa edulis in comparison to phenytoin and phenobarbital.
Topics: Administration, Oral; Animals; Anticonvulsants; Disease Models, Animal; Electroshock; Injections, Subcutaneous; Male; Mexico; Pentylenetetrazole; Phenobarbital; Phenytoin; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Seizures | 1995 |
Synthesis and anticonvulsant activity of some new 3-(p-sulfamoylphenyl)-4(3H)-quinazolinones.
Topics: Animals; Anticonvulsants; Anura; Female; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Pentylenetetrazole; Phenobarbital; Quinazolines | 1994 |
Pharmacodynamics of phenobarbital anesthesia and pentylenetetrazol-induced maximal seizures in a rat model of neoplastic spinal cord compression.
Topics: Anesthesia; Animals; Histiocytoma, Benign Fibrous; Male; Paraplegia; Pentylenetetrazole; Phenobarbital; Rats; Seizures; Spinal Cord Compression; Spinal Cord Neoplasms; Tremor | 1994 |
The effect of immunosuppression by total-body irradiation on the pharmacodynamics of centrally active drugs in rats.
Topics: Animals; Brain; Central Nervous System Agents; Central Nervous System Depressants; Ethanol; Female; Immunosuppression Therapy; Pentylenetetrazole; Phenobarbital; Rats; Seizures; Theophylline; Whole-Body Irradiation | 1994 |
[The antiepileptic effects of the combined action of the new 1,4-dihydropyridine derivative glutapyrone with sodium valproate and phenobarbital].
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Dihydropyridines; Drug Evaluation, Preclinical; Drug Therapy, Combination; Electroshock; Epilepsies, Partial; Epilepsy, Generalized; Glutamates; Male; Mice; Mice, Inbred ICR; Pentylenetetrazole; Phenobarbital; Rats; Rats, Wistar; Valproic Acid | 1993 |
Antiepileptic drugs--their effects on kindled seizures and kindling-induced learning impairments.
Topics: Animals; Anticonvulsants; Avoidance Learning; Cognition; Dose-Response Relationship, Drug; Ethosuximide; Kindling, Neurologic; Learning Disabilities; Male; Pentylenetetrazole; Phenobarbital; Rats; Rats, Wistar; Seizures; Valproic Acid | 1995 |
Synthesis and anticonvulsant activity of new thiazolidinone and thioxoimidazolidinone derivatives derived from furochromones.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry, Physical; Convulsants; Imidazoles; Khellin; Male; Mice; Pentylenetetrazole; Phenobarbital; Seizures; Thiazoles | 1997 |
A neuropharmacological analysis of PTZ-induced kindling in mice.
Topics: Aging; Animals; Anticonvulsants; Convulsants; Diazepam; Glutamic Acid; Kindling, Neurologic; Male; Membranes; Mice; Pentylenetetrazole; Phenobarbital | 1998 |
[Spasmophilia in children and the anticonvulsant properties of a new Ukrainian preparation containing a pyrimidine derivative].
Topics: Animals; Anticonvulsants; Aspirin; Caffeine; Child; Convulsants; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation, Preclinical; Humans; Mice; Pentylenetetrazole; Phenobarbital; Tablets; Tetany | 1998 |
N(G)-nitro-L-arginine impairs the anticonvulsive action of ethosuximide against pentylenetetrazol.
Topics: Animals; Anticonvulsants; Arginine; Convulsants; Diazepam; Drug Interactions; Enzyme Inhibitors; Ethosuximide; Male; Mice; Nitroarginine; Pentylenetetrazole; Phenobarbital; Psychomotor Performance; Seizures; Valproic Acid | 1999 |
Effect of adenosinergic modulation on the anticonvulsant effect of phenobarbitone and carbamazepine.
Topics: Adenosine; Animals; Anticonvulsants; Carbamazepine; Convulsants; Drug Combinations; Male; Pentylenetetrazole; Phenobarbital; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Seizures; Theophylline; Xanthines | 1999 |
Anticonvulsant properties of linalool in glutamate-related seizure models.
Topics: Acyclic Monoterpenes; Animals; Anticonvulsants; Cerebral Cortex; Disease Models, Animal; Dizocilpine Maleate; Glutamic Acid; Kindling, Neurologic; Male; Monoterpenes; N-Methylaspartate; Pentylenetetrazole; Phenobarbital; Quinolinic Acid; Radioligand Assay; Rats; Rats, Wistar; Seizures; Terpenes | 1999 |
Casimiroa edulis seed extracts show anticonvulsive properties in rats.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Male; Mexico; Pentylenetetrazole; Phenobarbital; Phenytoin; Plant Extracts; Prohibitins; Propylene Glycol; Rats; Rats, Wistar; Solubility; Time Factors | 1999 |
Antiepileptogenic properties of phenobarbital: behavior and neurochemical analysis.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Convulsants; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Mice; Pentylenetetrazole; Phenobarbital; Seizures | 2000 |
Enhanced anticonvulsant activity of neuroactive steroids in a rat model of catamenial epilepsy.
Topics: Allosteric Regulation; Animals; Anticonvulsants; Benzodiazepinones; Desoxycorticosterone; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Female; Menstrual Cycle; Pentylenetetrazole; Phenobarbital; Pregnanolone; Pseudopregnancy; Rats; Rats, Sprague-Dawley; Receptors, GABA; Steroids; Substance Withdrawal Syndrome; Valproic Acid | 2001 |
Functionalized amino acid anticonvulsants: synthesis and pharmacological evaluation of conformationally restricted analogues.
Topics: Amino Acids; Animals; Anticonvulsants; Catalysis; Crystallography, X-Ray; Cyclization; Drug Design; Hydantoins; Lactams; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Conformation; Molecular Structure; Neuroblastoma; Pentylenetetrazole; Phenobarbital; Phenytoin; Proline; Rats; Seizures; Sodium Channels; Stereoisomerism; Structure-Activity Relationship; Tetrazoles; Tumor Cells, Cultured | 2001 |
The pentylenetetrazole-kindling model of epilepsy in SAMP8 mice: behavior and metabolism.
Topics: Aging; Amino Acids; Animals; Anticonvulsants; Behavior, Animal; Brain; Convulsants; Epilepsy; Excitatory Amino Acid Antagonists; GABA Antagonists; Hypnotics and Sedatives; Kindling, Neurologic; Mice; Pentylenetetrazole; Phenobarbital; Time Factors | 2002 |
Effects of striatal injections of GABA(A) receptor agonists and antagonists in a genetic animal model of paroxysmal dystonia.
Topics: Animals; Bicuculline; Binding Sites; Corpus Striatum; Cricetinae; Dystonia; Female; Flumazenil; Flurazepam; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Male; Mesocricetus; Microinjections; Muscimol; Pentylenetetrazole; Phenobarbital | 2002 |
GABA(A)-benzodiazepine receptor complex sensitivity in 5-HT(1A) receptor knockout mice on a 129/Sv background.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Diazepam; Ethanol; Fever; Flumazenil; GABA Antagonists; Hypnotics and Sedatives; Male; Maze Learning; Mice; Mice, Knockout; Pentylenetetrazole; Phenobarbital; Receptors, GABA-A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reflex; Species Specificity; Stress, Physiological | 2002 |
Pharmacological evaluation of some new 1-substituted-4-hydroxy-phthalazines.
Topics: Amphetamine; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine; Heart; Magnetic Resonance Spectroscopy; Mice; Motor Activity; Myocardial Contraction; Pentylenetetrazole; Phenobarbital; Phthalazines; Ranidae; Seizures; Structure-Activity Relationship | 2002 |
The pentylenetetrazole-kindling model of epilepsy in SAMP8 mice: glial-neuronal metabolic interactions.
Topics: Acetic Acid; Age Factors; Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Epilepsy; Glucose; Kindling, Neurologic; Magnetic Resonance Spectroscopy; Mice; Neuroglia; Neurons; Pentylenetetrazole; Phenobarbital | 2003 |
[Changes in the motor activity after pentazole administration in irradiated rats under the influence of phenobarbital inhibition].
Topics: Animals; Motor Activity; Movement; Pentylenetetrazole; Phenobarbital; Radiation Injuries, Experimental; Rats | 1960 |
[Studies on the strength of action of the analeptics bemegride, pentylenetetrazole and picrotoxin in phenobarbital-hydroxydione-ethinamate narcosis and on reciprocal antagonism].
Topics: Bemegride; Carbamates; Central Nervous System Stimulants; Hypnotics and Sedatives; Pentylenetetrazole; Phenobarbital; Picrotoxin; Pregnanediones; Stupor | 1963 |
PHARMACOLOGICAL PROPERTIES OF PENTAERYTHRITOL DERIVATIVES. II.MONOBENZALPENTAERYTHRITOL, A COMPOUND STIMULATING THE CENTRAL NERVOUS SYSTEM.
Topics: Cats; Central Nervous System Stimulants; Mephenesin; Mice; Pentylenetetrazole; Pharmacology; Phenobarbital; Propylene Glycols; Rabbits; Rats; Research; Respiration; Seizures; Toxicology | 1962 |
CONTRASTING BEHAVIORAL, PHARMACOLOGICAL, NEUROPHYSIOLOGICAL, AND BIOCHEMICAL PROFILES OF C57 B1/6 AND SC-I STRAINS OF MICE.
Topics: Adrenal Glands; Aggression; Animals; Avoidance Learning; Behavior, Animal; Chlorpromazine; Mice; Neurophysiology; Norepinephrine; Pentylenetetrazole; Phenobarbital; Psychopharmacology; Research; Reserpine; Seizures; Serotonin | 1963 |
A PROPOSED COMMON MECHANISM OF ACTION FOR GENERAL AND LOCAL ANAESTHETICS IN THE CENTRAL NERVOUS SYSTEM.
Topics: Action Potentials; Anesthesia, Local; Anesthetics, Local; Animals; Cats; Central Nervous System; Cerebral Cortex; Ether; Mice; Neurons; Pentobarbital; Pentylenetetrazole; Pharmacology; Phenobarbital; Procaine; Research; Seizures | 1963 |
STIMULANT ACTION OF PYRIDYL DERIVATIVES OF BENZODIOXANS AND BENZODIOXEPANS.
Topics: Animals; Anticonvulsants; Atropine; Bemegride; Central Nervous System Agents; Central Nervous System Stimulants; Chlorisondamine; Chlorpromazine; Diazepam; Mephenesin; Meprobamate; Mice; Pentylenetetrazole; Pharmacology; Phenobarbital; Phenytoin; Picrotoxin; Research; Seizures; Strychnine; Tranquilizing Agents | 1963 |
EFFECTS OF DRUGS ON THE ELECTRIC KNIFE FISH, EIGENMANNIA VIRESCENS.
Topics: Animals; Electric Fish; Electric Organ; Electrophysiological Phenomena; Electrophysiology; Fishes; Gymnotiformes; Methylphenidate; Morphine; Nalorphine; Pentylenetetrazole; Pharmacology; Phenobarbital; Research | 1963 |
ANTIMALARIALS AND OTHER ANTICONVULSANT DRUGS: PREDICTIVE VALIDITY OF LABORATORY TESTS.
Topics: Animals; Anticonvulsants; Antimalarials; Chloroquine; Electric Stimulation; Hydroxychloroquine; Mice; Pentylenetetrazole; Pharmacology; Phenobarbital; Phenytoin; Quinacrine; Research; Seizures | 1964 |
SYNTHESIS AND PHARMACOLOGICAL PROPERTIES OF PHENYL-SUBSTITUTED BIURETS.
Topics: Atropine; Biuret; Chemistry, Pharmaceutical; Gastric Juice; Meprobamate; Mice; Nicotine; Pentylenetetrazole; Peptic Ulcer; Pharmacology; Phenformin; Phenobarbital; Picrotoxin; Rats; Research; Seizures; Strychnine; Toxicology; Urea | 1963 |
COMPARATIVE NEUROTOXICITY AND ANTIPENTYLENETETRAZOL ACTIVITY OF SOME PIPERIDINEDIONES.
Topics: Bemegride; Glutethimide; Hypnotics and Sedatives; Mice; Pentylenetetrazole; Pharmacology; Phenobarbital; Piperidines; Research; Seizures; Toxicology | 1964 |
ANTICONVULSANTS. I. DIBENZO(A,D)CYCLOHEPTADIENE-5-CARBOXAMIDE AND RELATED COMPOUNDS.
Topics: Amides; Anticonvulsants; Ataxia; Chemistry, Pharmaceutical; Mice; Pentylenetetrazole; Pharmacology; Phenobarbital; Phenytoin; Primidone; Research; Seizures; Toxicology | 1964 |
THE PLACE OF ACETYLSALICYLIC ACID IN PSYCHOPHARMACOLOGY. AN EXPERIMENTAL STUDY.
Topics: Amphetamine; Amphetamines; Animals; Aspirin; Body Temperature Regulation; Chlordiazepoxide; Chlorpromazine; Electrophysiology; Ether; Guinea Pigs; Hexobarbital; Meprobamate; Mice; Morphine; Nikethamide; Pain; Pentylenetetrazole; Pharmacology; Phenobarbital; Poisoning; Psychopharmacology; Rabbits; Research; Sensory Receptor Cells; Sleep; Strychnine; Thiopental | 1963 |
THE ABSENCE OF ANTICONVULSANT PROPERTIES OF QUINACRINE AND CHLOROQUINE IN MICE.
Topics: Anticonvulsants; Chloroquine; Mice; Pentylenetetrazole; Pharmacology; Phenobarbital; Quinacrine; Research; Seizures; Toxicology | 1964 |
ALTERATIONS IN THE ACTIVITY OF PENTOTHAL, PHENOBARBITAL, PENTYLENETETRAZOL, AND STRYCHNINE BY CHOLINESTERASE INHIBITORS.
Topics: Acetylcholine; Anesthesia; Atropine; Cholinesterase Inhibitors; Isoflurophate; Mice; Neostigmine; Pentylenetetrazole; Pharmacology; Phenobarbital; Physostigmine; Research; Seizures; Strychnine; Thiopental; Toxicology | 1964 |
NOTE ON THE INTERACTIONS OF AMPHETAMINE WITH ANTICONVULSANT DRUGS.
Topics: Amphetamine; Amphetamines; Animals; Anticonvulsants; Electricity; Electroshock; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Mice; Pentylenetetrazole; Pharmacology; Phenobarbital; Phenytoin; Research; Seizures | 1964 |
[EXPERIMENTAL STUDIES ON THE EFFECT OF SOME PHARMACOLOGICAL PREPARATIONS ON THE ANESTHETIC ACTIVITY OF COCAINE].
Topics: Adjuvants, Anesthesia; Anesthetics; Anura; Caffeine; Chlorpromazine; Cocaine; Ephedrine; Epinephrine; Guinea Pigs; Humans; Nitrates; Pentylenetetrazole; Pharmacology; Phenobarbital; Rabbits; Research; Reserpine | 1964 |
CERTAIN PHARMACOLOGICAL PROPERTIES OF 3-ETHYL-2-METHYL-2-PHENYLSUCCINIMIDE.
Topics: Anticonvulsants; Mental Disorders; Meprobamate; Mice; Pentylenetetrazole; Peptic Ulcer; Pharmacology; Phenobarbital; Pyrrolidinones; Rats; Research; Seizures; Stress, Physiological; Toxicology | 1964 |
EFFECTS OF CORTICAL SPREADING DEPRESSION AND DRUGS UPON AUDIOGENIC SEIZURES IN RATS.
Topics: Brain; Cerebral Cortex; Cortical Spreading Depression; Electrophysiology; Epilepsy; Epilepsy, Reflex; Pentylenetetrazole; Pharmacology; Phenobarbital; Rats; Research; Seizures; Sound | 1965 |
Isobols of dose-effect relations in the combination of pentylenetetrazole and phenobarbital.
Topics: Barbiturates; Humans; Pentylenetetrazole; Phenobarbital | 1955 |
Design and synthesis of some new derivatives of 3H-quinazolin-4-one with promising anticonvulsant activity.
Topics: Animals; Anticonvulsants; Convulsants; Dose-Response Relationship, Drug; Drug Design; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mice; Pentylenetetrazole; Phenobarbital; Quinazolines; Spectrophotometry, Infrared | 2003 |
[Spasmolytic effect of phenobarbital, and a complex association of total extracts of Datura and Scopolia (sanalepsi); their respective antidotal effect to cardiazol, and their differential toxicity].
Topics: Barbital; Datura; Parasympatholytics; Pentylenetetrazole; Phenobarbital; Scopolia | 1950 |
Isobolographic and subthreshold analysis of interactions among felbamate and four conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice.
Topics: Animals; Anticonvulsants; Behavior, Animal; Clonazepam; Disease Models, Animal; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Epilepsies, Myoclonic; Ethosuximide; Felbamate; Female; Humans; Lethal Dose 50; Mice; Motor Activity; Neurotoxicity Syndromes; Pentylenetetrazole; Phenobarbital; Phenylcarbamates; Propylene Glycols; Seizures; Valproic Acid | 2004 |
Anticonvulsant efficacy of the low-affinity partial benzodiazepine receptor agonist ELB 138 in a dog seizure model and in epileptic dogs with spontaneously recurrent seizures.
Topics: Animals; Anticonvulsants; Bromides; Chronic Disease; Disease Models, Animal; Dog Diseases; Dogs; Drug Therapy, Combination; Epilepsy; Flumazenil; GABA Agonists; GABA-A Receptor Agonists; Imidazoles; Pentylenetetrazole; Phenobarbital; Potassium Compounds; Primidone; Receptors, GABA-A; Seizures; Substance Withdrawal Syndrome; Treatment Outcome | 2004 |
Synthesis and pharmacological evaluation of some DL-dichlorophenyl alcohol amides anticonvulsants.
Topics: Amides; Animals; Anticonvulsants; Convulsants; Hydrocarbons, Chlorinated; Magnetic Resonance Spectroscopy; Male; Mice; Pentylenetetrazole; Phenobarbital; Seizures; Structure-Activity Relationship | 2004 |
Toxicological and pharmacological effects of D-arginine.
Topics: Adrenergic beta-Antagonists; Animals; Arginine; Autonomic Nervous System; Behavior, Animal; Betamethasone; Central Nervous System; Dose-Response Relationship, Drug; Drug Interactions; Hypnotics and Sedatives; Male; Mice; Motor Activity; Pentylenetetrazole; Phenobarbital; Propranolol; Seizures; Sleep | 2005 |
Pharmacodynamic and/or pharmacokinetic characteristics of interactions between loreclezole and four conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice: an isobolographic analysis.
Topics: Animals; Anticonvulsants; Clonazepam; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Ethosuximide; Kindling, Neurologic; Linear Models; Male; Mice; Pentylenetetrazole; Phenobarbital; Seizures; Triazoles; Valproic Acid | 2005 |
Neuropharmacological effects of deltamethrin in rats.
Topics: Animals; Ataxia; Brain; Female; gamma-Aminobutyric Acid; Insecticides; Male; Molecular Structure; Nitriles; Pentylenetetrazole; Phenobarbital; Pyrethrins; Rats; Rats, Wistar; Seizures; Sleep | 2006 |
Characterization of the anticonvulsant, behavioral and pharmacokinetic interaction profiles of stiripentol in combination with clonazepam, ethosuximide, phenobarbital, and valproate using isobolographic analysis.
Topics: Animals; Anticonvulsants; Brain Chemistry; Clonazepam; Dioxolanes; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Ethosuximide; Male; Mice; Neurotoxicity Syndromes; Pentylenetetrazole; Phenobarbital; Seizures; Valproic Acid | 2006 |
Increased P-glycoprotein expression and decreased phenobarbital distribution in the brain of pentylenetetrazole-kindled rats.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Brain; Brain Chemistry; Cerebral Cortex; Convulsants; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; Hypnotics and Sedatives; Kainic Acid; Kindling, Neurologic; Male; Muscarinic Agonists; Pentylenetetrazole; Phenobarbital; Pilocarpine; Rats; Rats, Sprague-Dawley; Rhodamine 123; Up-Regulation | 2007 |
Effects of gamma-decanolactone on seizures induced by PTZ-kindling in mice.
Topics: Animals; Anticonvulsants; Brain; Comet Assay; Convulsants; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Kindling, Neurologic; Lactones; Male; Mice; Nerve Degeneration; Pentylenetetrazole; Phenobarbital; Treatment Outcome | 2008 |
Synthesis of DL-fluorobenzenamides as anticonvulsants.
Topics: Animals; Anticonvulsants; Benzamides; Convulsants; Indicators and Reagents; Male; Mice; Pentylenetetrazole; Phenobarbital; Seizures; Structure-Activity Relationship | 2008 |
Isobolographic characterization of the anticonvulsant interaction profiles of levetiracetam in combination with clonazepam, ethosuximide, phenobarbital and valproate in the mouse pentylenetetrazole-induced seizure model.
Topics: Animals; Anticonvulsants; Clonazepam; Convulsants; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Ethosuximide; Levetiracetam; Male; Mice; Pentylenetetrazole; Phenobarbital; Piracetam; Seizures; Valproic Acid | 2009 |
Combined effects of epileptic seizure and phenobarbital induced overexpression of P-glycoprotein in brain of chemically kindled rats.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Behavior, Animal; Blotting, Western; Brain; Chromatography, High Pressure Liquid; DNA Primers; Epilepsy; Kindling, Neurologic; Male; Pentylenetetrazole; Phenobarbital; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Rhodamine 123 | 2010 |
Effect of metrazol on the electrical excitability of the respiratory center when depressed by phenobarbital.
Topics: Barbital; Barbiturates; Mental Disorders; Pentylenetetrazole; Phenobarbital; Psychomotor Agitation; Respiratory Center | 1947 |
Effects of WIN 55,212-2 mesylate (a synthetic cannabinoid) on the protective action of clonazepam, ethosuximide, phenobarbital and valproate against pentylenetetrazole-induced clonic seizures in mice.
Topics: Animals; Anticonvulsants; Avoidance Learning; Benzoxazines; Brain; Cannabinoid Receptor Agonists; Clonazepam; Disease Models, Animal; Drug Synergism; Ethosuximide; Hand Strength; Male; Mice; Morpholines; Naphthalenes; Pentylenetetrazole; Phenobarbital; Seizures; Valproic Acid | 2011 |
Effects of midazolam and phenobarbital on brain oxidative reactions induced by pentylenetetrazole in a convulsion model.
Topics: Animals; Brain; Cerebral Cortex; Disease Models, Animal; Gene Expression; Heme Oxygenase-1; Hippocampus; Hypothalamus; Male; Malondialdehyde; Mice; Midazolam; Oxidation-Reduction; Pentylenetetrazole; Phenobarbital; Seizures; Treatment Outcome | 2012 |
Synthesis and biological evaluation of some novel quinoxaline derivatives as anticonvulsant agents.
Topics: Animals; Anticonvulsants; Convulsants; Dose-Response Relationship, Drug; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Pentylenetetrazole; Phenobarbital; Quinoxalines; Seizures; Structure-Activity Relationship | 2011 |
Striking differences in proconvulsant-induced alterations of seizure threshold in two rat models.
Topics: Animals; Anticonvulsants; Caffeine; Central Nervous System Stimulants; Chlorpromazine; Convulsants; Dextroamphetamine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Electroshock; Male; Pentylenetetrazole; Phenobarbital; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Reaction Time; Seizures; Theophylline; Time Factors; Tramadol | 2012 |
The novel antiepileptic drug imepitoin compares favourably to other GABA-mimetic drugs in a seizure threshold model in mice and dogs.
Topics: Animals; Anticonvulsants; Carbolines; Dogs; Dose-Response Relationship, Drug; Drug Partial Agonism; Female; GABA-A Receptor Agonists; Imidazoles; Male; Mice; Pentylenetetrazole; Phenobarbital; Seizures | 2013 |
A novel prodrug-based strategy to increase effects of bumetanide in epilepsy.
Topics: Action Potentials; Animals; Animals, Newborn; Brain; Bumetanide; Convulsants; Disease Models, Animal; Diuretics; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Epilepsy; Humans; In Vitro Techniques; Mice; Neurons; Pentylenetetrazole; Phenobarbital; Rats; Rats, Sprague-Dawley; Rats, Wistar; Serum; Sodium Potassium Chloride Symporter Inhibitors; Species Specificity; Time Factors | 2014 |
Montelukast potentiates the anticonvulsant effect of phenobarbital in mice: an isobolographic analysis.
Topics: Acetates; Animals; Anticonvulsants; Convulsants; Cyclopropanes; Dose-Response Relationship, Drug; Drug Synergism; Electroencephalography; Female; Leukotriene Antagonists; Mice; Motor Activity; Pentylenetetrazole; Phenobarbital; Quinolines; Seizures; Sulfides | 2015 |
Design and Synthesis of Novel Phenylpiperazine Derivatives as Potential Anticonvulsant Agents.
Topics: Animals; Anticonvulsants; Brain; Disease Models, Animal; Drug Design; Male; Mice; Molecular Structure; Pentylenetetrazole; Phenobarbital; Piperazines; Seizures; Structure-Activity Relationship; Strychnine | 2015 |
Interactions between an antidepressant reboxetine and four classic antiepileptic drugs in the mouse model of myoclonic seizures.
Topics: Animals; Anticonvulsants; Antidepressive Agents; Avoidance Learning; Clonazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsies, Myoclonic; Ethosuximide; Male; Mice; Morpholines; Motor Skills; Pentylenetetrazole; Phenobarbital; Reboxetine; Valproic Acid | 2015 |
Montelukast reduces seizures in pentylenetetrazol-kindled mice.
Topics: Acetates; Animals; Anticonvulsants; Blotting, Western; Convulsants; Cyclopropanes; Kindling, Neurologic; Leukotriene Antagonists; Male; Mice; Pentylenetetrazole; Phenobarbital; Quinolines; Receptors, Leukotriene; Seizures; Sulfides; Time Factors; Treatment Outcome | 2016 |
The bumetanide prodrug BUM5, but not bumetanide, potentiates the antiseizure effect of phenobarbital in adult epileptic mice.
Topics: Animals; Anticonvulsants; Bumetanide; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroencephalography; Electroshock; Epilepsy, Temporal Lobe; Mice; Pentylenetetrazole; Phenobarbital; Pilocarpine; Prodrugs | 2016 |
Evaluation of the pentylenetetrazole seizure threshold test in epileptic mice as surrogate model for drug testing against pharmacoresistant seizures.
Topics: Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Drug Resistance; Epilepsy; GABA Antagonists; Levetiracetam; Male; Mice; Pentylenetetrazole; Phenobarbital; Pilocarpine; Piracetam; Rats; Seizures; Status Epilepticus; Valproic Acid | 2016 |
Seizures triggered by pentylenetetrazol in marmosets made chronically epileptic with pilocarpine show greater refractoriness to treatment.
Topics: Animals; Anticonvulsants; Brain; Callithrix; Carbamazepine; Chronic Disease; Disease Models, Animal; Electrocorticography; Epilepsy; Female; Immunohistochemistry; Male; Neuropeptide Y; Pentylenetetrazole; Phenobarbital; Pilocarpine; Proto-Oncogene Proteins c-fos; Seizures; Valproic Acid | 2016 |
Cunaniol-elicited seizures: Behavior characterization and electroencephalographic analyses.
Topics: Animals; Anticonvulsants; Convulsants; Diazepam; Disease Models, Animal; Electroencephalography; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Seizures | 2018 |
Functional characterization of novel bumetanide derivatives for epilepsy treatment.
Topics: Animals; Anticonvulsants; Blood-Brain Barrier; Brain; Bumetanide; Convulsants; Disease Models, Animal; Diuretics; Dose-Response Relationship, Drug; Drug Resistant Epilepsy; Electroencephalography; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Kainic Acid; Mice; Pentylenetetrazole; Phenobarbital; Seizures; Sodium Potassium Chloride Symporter Inhibitors; Solute Carrier Family 12, Member 2 | 2020 |
Effect of aliskiren on the anticonvulsant activity of antiepileptic drugs against 6 Hz-induced psychomotor seizures in mice.
Topics: Amides; Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Disease Models, Animal; Drug Interactions; Epilepsy, Temporal Lobe; Fumarates; Mice; Pentylenetetrazole; Phenobarbital; Seizures | 2020 |
Caffeine intoxication: Behavioral and electrocorticographic patterns in Wistar rats.
Topics: Animals; Anticonvulsants; Caffeine; Diazepam; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Seizures | 2022 |
Unmasking hidden risks: The surprising link between PDE5 inhibitors and seizure susceptibility.
Topics: Animals; Anticonvulsants; Diazepam; Humans; Male; Pentylenetetrazole; Phenobarbital; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Rats; Rats, Wistar; Seizures; Sildenafil Citrate; Sulfones; Tadalafil | 2023 |