Compounds > phenobarbital

phenobarbital and pentoxyresorufin

phenobarbital has been researched along with pentoxyresorufin in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19902 (16.67)18.7374
1990's7 (58.33)18.2507
2000's3 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Elovaara, E; Gelboin, HV; Hietanen, E; Nakajima, T; Park, SS; Vainio, H1
Heubel, F; Netter, KJ; Vesell, ES1
Burke, MD; Cameron, JW; Guengerich, FP; Lubet, RA; Mayer, RT; Nims, RW; Wolff, T1
Castell, JV; Donato, MT; Gómez-Lechón, MJ1
Belica, PS; Lubet, RA; Manchand, PS; McClain, RM; Mellini, DW; Nims, RW; Thomas, PE; Utermahlen, WE1
Konishi, H; Morita, K; Yamaji, A1
Caudill, D; Johnson, DR; Lehman-McKeeman, LD1
Fish, D; Gururajan, L; Khan, MA; Poria, MS; Qadri, SY; Tomar, S1
Dhawan, A; Parmar, D; Seth, PK1
Szakács, T; Vereczkey, L; Veres, Z1
Commandeur, JN; Irth, H; Kool, J; van Elswijk, DA; van Liempd, SM; van Rossum, H; Vermeulen, NP1
Etzrodt, J; Glöckner, R; Lupp, A; Müller, D1

Other Studies

12 other study(ies) available for phenobarbital and pentoxyresorufin

ArticleYear
Monoclonal antibody-directed characterization of benzene, ethoxyresorufin and pentoxyresorufin metabolism in rat liver microsomes.
    Biochemical pharmacology, 1990, Sep-15, Volume: 40, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Benzene; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ethanol; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oxazines; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains

1990
Brief maternal deprivation of rats reduces hepatic mixed function oxidase activities.
    Life sciences, 1989, Volume: 45, Issue:19

    Topics: Aminopyrine; Animals; Benzphetamine; Biotransformation; Body Weight; Coumarins; Enzyme Induction; Female; Handling, Psychological; Male; Maternal Deprivation; Microsomes, Liver; Mixed Function Oxygenases; Oxazines; Phenobarbital; Rats; Rats, Inbred Strains

1989
Dealkylation of pentoxyresorufin: a rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rat.
    Archives of biochemistry and biophysics, 1985, Volume: 238, Issue:1

    Topics: Aminopyrine N-Demethylase; Animals; Aroclors; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Dealkylation; Enzyme Induction; Male; Methylcholanthrene; Microsomes, Liver; Oxazines; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Substrate Specificity

1985
Effect of model inducers on cytochrome P450 activities of human hepatocytes in primary culture.
    Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:5

    Topics: Adult; Aged; Cells, Cultured; Clofibric Acid; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Ethanol; Female; Humans; Isoenzymes; Liver; Male; Methylcholanthrene; Middle Aged; Nitrophenols; Oxazines; Oxidation-Reduction; Phenobarbital; Safrole; Substrate Specificity; Testosterone

1995
Comparative pharmacodynamics of hepatic cytochrome P450 2B induction by 5,5-diphenyl- and 5,5-diethyl-substituted barbiturates and hydantoins in the male F344/NCr rat.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:1

    Topics: Alkylation; Animals; Barbital; Cytochrome P-450 Enzyme System; Enzyme Induction; Hydantoins; Liver; Male; Organ Size; Oxazines; Phenobarbital; Phenytoin; Rats; Rats, Inbred F344

1994
Involvement of CYP2E in 8-hydroxylation of theophylline in mouse hepatic microsomes-difference from its N-demethylations.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:4

    Topics: Acetone; Aminoacetonitrile; Aminopyrine; Animals; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fomepizole; Hydroxylation; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Nitrophenols; Oxazines; Phenobarbital; Pregnenolone Carbonitrile; Pyrazoles; Theophylline

1996
Induction and inhibition of mouse cytochrome P-450 2B enzymes by musk xylene.
    Toxicology and applied pharmacology, 1997, Volume: 142, Issue:1

    Topics: Administration, Oral; Animals; Aryl Hydrocarbon Hydroxylases; Bacteria; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Intestines; Isoenzymes; Liver; Liver Neoplasms, Experimental; Male; Mice; Microsomes, Liver; Organ Size; Oxazines; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Perfume; Phenobarbital; Xylenes

1997
Induction of hepatic cytochrome P-450 by phenobarbital in semi-aquatic frog (Rana pipiens).
    Biochemical and biophysical research communications, 1998, Mar-27, Volume: 244, Issue:3

    Topics: Age Factors; Aldrin; Animals; Biological Evolution; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Gills; Larva; Liver; Lung; Male; Metamorphosis, Biological; Mice; Microsomes, Liver; Mixed Function Oxygenases; Oxazines; Perciformes; Phenobarbital; Rana pipiens; Rats; Sex Factors; Xenopus laevis

1998
Evidence for O-dealkylation of 7-pentoxyresorufin by cytochrome P450 2B1/2B2 isoenzymes in brain.
    Molecular and cellular biochemistry, 1998, Volume: 189, Issue:1-2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Brain; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Dealkylation; Immunoglobulin G; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Metyrapone; Oxazines; Phenobarbital; Rats; Rats, Wistar; Steroid Hydroxylases

1998
Effect of alpha-methyldopa on pentoxyresorufin O-dealkylation in liver microsomes from rats treated with phenobarbital.
    Archives of biochemistry and biophysics, 2001, Aug-01, Volume: 392, Issue:1

    Topics: Animals; Ascorbic Acid; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1 Inhibitors; Dopamine; Enzyme Inhibitors; Glutathione; Levodopa; Lipid Peroxidation; Male; Methyldopa; Microsomes, Liver; NADP; Oxazines; Phenobarbital; Rats; Rats, Wistar

2001
Development of three parallel cytochrome P450 enzyme affinity detection systems coupled on-line to gradient high-performance liquid chromatography.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:4

    Topics: Animals; beta-Naphthoflavone; Chromatography, High Pressure Liquid; Coumarins; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Induction; Enzyme Inhibitors; Flow Injection Analysis; Liver; Microsomes, Liver; Oxazines; Phenobarbital; Rats; Reproducibility of Results; Substrate Specificity; Time Factors

2007
Precision-cut liver slices from rats of different ages: basal cytochrome P450-dependent monooxygenase activities and inducibility.
    Analytical and bioanalytical chemistry, 2008, Volume: 392, Issue:6

    Topics: Aging; Animals; Anti-Inflammatory Agents; beta-Naphthoflavone; Coumarins; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dexamethasone; Dimethyl Sulfoxide; Enzyme Induction; Enzyme Inhibitors; Hydroxylation; Liver; Male; Mixed Function Oxygenases; Organ Culture Techniques; Oxazines; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Wistar; Testosterone; Time Factors

2008