Compounds > phenobarbital

phenobarbital and oltipraz

phenobarbital has been researched along with oltipraz in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (36.36)18.2507
2000's6 (54.55)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cherrington, NJ; Klaassen, CD; Maher, JM; Slitt, AL1
Cherrington, NJ; Huang, W; Klaassen, CD; Maher, JM; Moore, DD; Slitt, AL; Wan, YJ; Zhang, J; Zhang, XX1
Fardel, O; Gilmore, KS; Guillouzo, A; Kensler, TW; Ketterer, B; Langouet, S; Meunier, B; Meyer, DJ; Morel, F; Tu, CP1
Ellis, EM; Hayes, JD; Judah, DJ; Neal, GE; O'Connor, T1
Corcos, L; Fardel, O; Guillouzo, A; Ketterer, B; Langouët, S; Meyer, DJ; Morel, F1
de Sousa, G; Guillouzo, A; Langouët, S; Lorenzon, G; Nicolas, F; Placidi, M; Rahmani, R1
Bae, SK; Kim, T; Kim, YH; Lee, MG; Lee, SJ1
Boursier-Neyret, C; Fardel, O; Jigorel, E; Le Vee, M; Parmentier, Y1
Beilke, LD; Besselsen, DG; Cheng, Q; Cherrington, NJ; Kulkarni, S; Slitt, AL1
Aleksunes, LM; Beilke, LD; Besselsen, DG; Cherrington, NJ; Dvorak, K; Klaassen, CD; Olson, ER1
Droździk, A; Laszczyńska, M; Wajda, A; Łapczuk, J1

Other Studies

11 other study(ies) available for phenobarbital and oltipraz

ArticleYear
Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:9

    Topics: Acetaminophen; Allyl Compounds; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Bile; Blotting, Western; Branched DNA Signal Amplification Assay; Drug Resistance, Multiple; Kidney; Liver; Male; Mitochondrial Proteins; Phenobarbital; Pyrazines; Rats; Rats, Sprague-Dawley; Ribosomal Proteins; RNA, Messenger; Saccharomyces cerevisiae Proteins; Stilbenes; Sulfides; Thiones; Thiophenes; Time Factors

2003
Induction of multidrug resistance protein 3 (mrp3) in vivo is independent of constitutive androstane receptor.
    Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:11

    Topics: Animals; Constitutive Androstane Receptor; Enzyme Induction; Female; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Multidrug Resistance-Associated Proteins; Phenobarbital; Rats; Rats, Inbred WKY; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Transcription Factors

2003
Preferential increase of glutathione S-transferase class alpha transcripts in cultured human hepatocytes by phenobarbital, 3-methylcholanthrene, and dithiolethiones.
    Cancer research, 1993, Jan-15, Volume: 53, Issue:2

    Topics: Cells, Cultured; Enzyme Induction; Gene Expression; Glutathione Transferase; Humans; Liver; Methylcholanthrene; Phenobarbital; Pyrazines; RNA, Messenger; Thiones; Thiophenes

1993
Regulation of carbonyl-reducing enzymes in rat liver by chemoprotectors.
    Cancer research, 1996, Jun-15, Volume: 56, Issue:12

    Topics: Aldehyde Reductase; Animals; Antioxidants; Barbiturates; Butylated Hydroxyanisole; Carcinogens; Enzyme Induction; Ethoxyquin; Liver; Methylcholanthrene; Oxidation-Reduction; Phenobarbital; Pyrazines; Rats; Thiones; Thiophenes

1996
A comparison of the effect of inducers on the expression of glutathione-S-transferases in the liver of the intact rat and in hepatocytes in primary culture.
    Hepatology (Baltimore, Md.), 1996, Volume: 23, Issue:4

    Topics: Animals; Cells, Cultured; Enzyme Induction; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Liver; Male; Methylcholanthrene; Phenobarbital; Pyrazines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thiones; Thiophenes

1996
Increase of cytochrome P-450 1A and glutathione transferase transcripts in cultured hepatocytes from dogs, monkeys, and humans after cryopreservation.
    Cell biology and toxicology, 1996, Volume: 12, Issue:4-6

    Topics: Animals; Cell Survival; Cells, Cultured; Cryopreservation; Cyclopentanes; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Dogs; Glutathione Transferase; Haplorhini; Humans; Liver; Phenobarbital; Pyrazines; RNA, Messenger; Thiones; Thiophenes

1996
Effect of enzyme inducers and inhibitors on the pharmacokinetics of oltipraz in rats.
    The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:4

    Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Isoenzymes; Isoniazid; Male; Metabolic Clearance Rate; Methylcholanthrene; Microsomes, Liver; Models, Animal; Phenobarbital; Pyrazines; Rats; Rats, Sprague-Dawley; Thiones; Thiophenes

2005
Differential regulation of sinusoidal and canalicular hepatic drug transporter expression by xenobiotics activating drug-sensing receptors in primary human hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:10

    Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Constitutive Androstane Receptor; Gene Expression Regulation; Hepatocytes; Humans; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; NF-E2-Related Factor 2; Phenobarbital; Polychlorinated Dibenzodioxins; Pregnane X Receptor; Pyrazines; Receptors, Aryl Hydrocarbon; Receptors, Cytoplasmic and Nuclear; Receptors, Drug; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; Rifampin; RNA, Messenger; Symporters; Thiones; Thiophenes; Transcription Factors; Xenobiotics

2006
Minimal role of hepatic transporters in the hepatoprotection against LCA-induced intrahepatic cholestasis.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 102, Issue:1

    Topics: Animals; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cholestasis, Intrahepatic; Cytoprotection; Disease Models, Animal; Lithocholic Acid; Liver; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Organic Anion Transporters, Sodium-Dependent; Phenobarbital; Protective Agents; Pyrazines; Pyridines; RNA, Messenger; Symporters; Thiones; Thiophenes; Time Factors; Up-Regulation

2008
Decreased apoptosis during CAR-mediated hepatoprotection against lithocholic acid-induced liver injury in mice.
    Toxicology letters, 2009, Jul-10, Volume: 188, Issue:1

    Topics: Animals; Apoptosis; bcl-X Protein; Caspase 3; Cholestasis, Intrahepatic; Constitutive Androstane Receptor; Cytoprotection; Disease Models, Animal; Lithocholic Acid; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Cell Leukemia Sequence 1 Protein; Phenobarbital; Pregnenolone Carbonitrile; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Pyridines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiones; Thiophenes; Transcription Factors

2009
Expression and functional regulation of the nuclear receptors AHR, PXR, and CAR, and the transcription factor Nrf2 in rat parotid gland.
    European journal of oral sciences, 2014, Volume: 122, Issue:4

    Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Nucleus; Constitutive Androstane Receptor; Cytoplasm; Dexamethasone; Gene Expression Regulation; Male; NF-E2-Related Factor 2; Parotid Gland; Phenobarbital; Polychlorinated Dibenzodioxins; Pregnane X Receptor; Pyrazines; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Salivary Ducts; Thiones; Thiophenes

2014