phenobarbital has been researched along with nitrophenols in 83 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 67 (80.72) | 18.7374 |
| 1990's | 9 (10.84) | 18.2507 |
| 2000's | 6 (7.23) | 29.6817 |
| 2010's | 1 (1.20) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cammer, PA; Hollingworth, RM | 1 |
| Elmamlouk, TH; Mukhtar, H | 1 |
| Belinsky, SA; Evans, RK; Kauffman, FC; Reinke, LA; Thurman, RG | 2 |
| Mardones, J; Sánchez, E; Tampier, L | 1 |
| Claude, JR; Jacqueson, A; Thevenin, M; Truhaut, R; Warnet, JM | 1 |
| Morisoli, LS; Rodriguez Garay, EA; Venera, GD | 1 |
| Bock, KW; Remmer, H; Rexer, B | 1 |
| Gram, TE; Guarino, AM; Litterst, CL; Mimnaugh, EG; Simon, RC | 1 |
| Gram, TE; Litterst, CI; Mimnaugh, EG | 1 |
| Burgschat, H; Netter, KJ | 1 |
| Jones, LS; Kauffman, FC; Marazzo, DP; Thurman, RG | 1 |
| Berggren, M; Moldéus, P; Vadi, H | 1 |
| Araki, K; Kaneto, H; Koida, M; Noda, T | 1 |
| Alcedo, JA; Bement, WJ; Hamilton, JW; Sinclair, JF; Sinclair, PR; Wetterhahn, KE | 1 |
| Del Villar, E; Gaule, C; Sanchez, E; Vega, P | 1 |
| Bement, WJ; Guzelian, PS; Lambrecht, LK; McCaffrey, J; Park, SS; Schenkman, JB; Sinclair, JF; Sinclair, PR; Smith, EL; Wood, SG | 1 |
| Hanioka, N; Hoshikawa, Y; Mitsui, T; Oguri, K; Yoshimura, H | 1 |
| Chauffert, M; Foliot, A; Myara, A; Touchard, D; Trivin, F | 1 |
| Malejka-Giganti, D; Ryzewski, CN | 1 |
| Lech, JJ; Vodicnik, MJ; Weitman, SD | 1 |
| Bock, KW; Fröhling, W; Remmer, H; Rexer, B | 1 |
| Aitio, A; Vainio, H | 1 |
| Hänninen, O; Vainio, H | 1 |
| Hietanen, E; Vainio, H | 1 |
| Netter, KJ | 1 |
| Bos, CJ; Emmelot, P | 1 |
| Ohlsson, JT; Wilson, IB | 1 |
| Neal, RA | 1 |
| Hardonk, MJ; Koudstaal, J | 1 |
| Cohen, JL; Jao, JY | 1 |
| Fouts, JR; Peters, MA | 1 |
| Atkins, C; Conney, AH; Haber, S; Kozma, C; Salvador, RA | 1 |
| Lombrozo, L; Mitoma, C | 1 |
| Zavon, MR | 1 |
| Henderson, PT; Jansen, PL | 1 |
| Wagstaff, DJ | 1 |
| McCarthy, WJ; St John, PA; Winefordner, JD | 1 |
| Vorne, M | 2 |
| Winsnes, A | 1 |
| Frei, J; Magnenat, P; Okolicsanyi, L | 1 |
| Bond, EJ; De Matteis, F | 1 |
| Mulder, GJ | 1 |
| LeValley, SE; Mitoma, C | 1 |
| Beuthin, PK; Bousquet, WF | 1 |
| Furner, RL; McCarthy, JS; Stitzel, RE; Van Dyke, K | 1 |
| Henderson, PT; Kersten, KJ | 1 |
| Henderson, PT | 1 |
| Fowler, JS | 1 |
| Alary, JG; Brodeur, J; Guay, P | 1 |
| Brown, DR; Murphy, SD | 1 |
| Dehn, RL; Mitoma, C; Tanabe, M | 1 |
| Fouts, JR; Gram, TE; Hansen, AR | 1 |
| Calderoni, FJ; Mitoma, C; Neubauer, SE; Tagg, JS; Tanabe, M; Yasuda, D | 1 |
| Ban, T | 1 |
| Dubois, KP; Tardiff, RG | 1 |
| Halac, E; Sicignano, C | 1 |
| DuBois, KP; Kinoshita, F | 1 |
| Ali, B; Kaur, S | 1 |
| Matsui, M; Watanabe, HK | 2 |
| Nousiainen, U | 1 |
| Hirata, M; Tonda, K | 1 |
| Nousiainen, U; Ryhänen, R | 1 |
| Mitchell, JR; Nelson, SD; Snodgrass, WR; Timbrell, JA | 1 |
| Ahotupa, M; Aitio, A; Parkki, MG | 1 |
| Mäntylä, E; Suolinna, EM | 1 |
| Reinke, LA; Sonawane, BR; Thurman, RG; Yaffe, SJ | 1 |
| Castell, JV; Donato, MT; Gómez-Lechón, MJ | 1 |
| Hattori, T; Hayashi, Y; Horio, F; Machino, S; Makino, S; Shibata, T; Yoshida, A | 1 |
| Conney, AH; Huang, MT; Suchar, LA; Zhu, BT | 1 |
| Konishi, H; Morita, K; Yamaji, A | 1 |
| Mazur, SP | 1 |
| Davies, DS; Edwards, RJ; Neubert, D; Schulz, TG; Thier, R; Wiebel, FA | 1 |
| Emerole, GO; Farombi, EO; Nwankwo, JO; Odutola, B; Wara, SH | 1 |
| Galchev, V; Kindt, E; Kostrubsky, VE; Ramachandran, V; Rose, K; Sinclair, JF; Sinz, M; Strom, SC; Venkataramanan, R; Wen, YH | 1 |
| Kuhn, UD; Müller, D; Rost, M | 1 |
| NETTER, KJ; SEIDEL, G | 1 |
| Hyun, SH; Jeon, TW; Jeong, HG; Jeong, TC; Jin, CH; Kim, DO; Kim, EJ; Kim, JA; Lee, BM; Lee, ES; Lee, SK; Moon, GI | 1 |
| Draper, A; Leonard, N; Ogilvie, BW; Parkinson, A | 1 |
| Batt, AM; Boutin, JA; Jacquier, A; Marlière, P; Siest, G | 1 |
| Chattipakorn, N; Chattipakorn, SC; Fucharoen, S; Jaiwongkam, T; Kerdphoo, S; Khamseekaew, J; Kumfu, S; Srichairatanakool, S; Wongjaikam, S | 1 |
2 review(s) available for phenobarbital and nitrophenols
| Article | Year |
|---|---|
Poisoning from pesticides: diagnosis and treatment.
Topics: Antidotes; Arsenic Poisoning; Atropine; Carbamates; Child; Cholinesterase Inhibitors; Cholinesterases; Dimercaprol; Emetics; Erythrocytes; Gastric Lavage; Herbicides; Humans; Hydrocarbons, Chlorinated; Insecticides; Nitrophenols; Organophosphorus Compounds; Oxygen; Pesticides; Phenobarbital; Poisoning; Pralidoxime Compounds; Respiration, Artificial; Rodenticides; Water | 1974 |
Phosphorimetry as an analytical approach in biochemistry.
Topics: Animals; Anticoagulants; Aspirin; Atropine; Blood Chemical Analysis; Chemical Phenomena; Chemistry, Physical; Chlorpromazine; Chromatography; Cocaine; Cold Temperature; Enzymes; Equipment and Supplies; Hot Temperature; Luminescent Measurements; Methods; Nitrophenols; Nucleic Acids; Phenobarbital; Procaine; Proteins; Solvents; Sulfonamides; Time Factors | 1967 |
81 other study(ies) available for phenobarbital and nitrophenols
| Article | Year |
|---|---|
Unusual substrate specificity in the oxidative dearylation of paraoxon analogs by mouse hepatic microsomal enzymes.
Topics: Animals; Chemical Phenomena; Chemistry; Hydrolysis; Kinetics; Male; Mice; Microsomes, Liver; Mixed Function Oxygenases; NADP; Nitrophenols; Paraoxon; Phenobarbital; Rana pipiens | 1976 |
trans-Stilbene oxide: a new inducer of rat liver microsomal UDP-glucuronyltransferase.
Topics: Animals; Enzyme Induction; Glucuronosyltransferase; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Nitrophenols; Phenobarbital; Rats; Stilbenes | 1979 |
p-Nitrophenol conjugation in perfused livers from normal and phenobarbital-treated rats: influence of nutritional state.
Topics: Adenine Nucleotides; Animals; Female; Glucuronosyltransferase; In Vitro Techniques; Liver; Liver Glycogen; Nitrophenols; Nutritional Physiological Phenomena; Phenobarbital; Rats; Time Factors | 1979 |
Receptors for morphine and opioids.
Topics: Age Factors; Animals; Dealkylation; Glucuronosyltransferase; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Morphine; Nalorphine; Nitrophenols; Phenobarbital; Rats; Receptors, Opioid; Time Factors | 1976 |
Accentuation of white phosphorus induced fatty liver by phenobarbitone in male rats compared to female rats.
Topics: Animals; Drug Synergism; Fatty Liver; Female; Male; Nitrophenols; Phenobarbital; Phosphorus; Rats; Sex Factors; Triglycerides | 1979 |
Degradation of parathion to p-nitrophenol by livers of rats treated with phenobarbital.
Topics: Animals; Caseins; Dietary Proteins; Liver; Nitrophenols; Parathion; Phenobarbital; Protein Deficiency; Rats | 1978 |
Relationship between microsomal hydroxylase and glucuronyltransferase.
Topics: Aminopyrine; Animals; Bilirubin; Biotransformation; Chloramphenicol; Cytochrome P-450 Enzyme System; Deoxycholic Acid; Female; Glucuronosyltransferase; Hexosyltransferases; Liver; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Naphthols; Nitrophenols; Phenobarbital; Polyethylene Glycols; Rats; Sex Factors; Sonication | 1975 |
Acute toxicity of substrates of the mixed function oxidase system in normal and phenobarbital-pretreated mice.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Aniline Compounds; Aniline Hydroxylase; Animals; Antipyrine; Cytochrome P-450 Enzyme System; Ethylmorphine-N-Demethylase; Glucuronosyltransferase; Lethal Dose 50; Liver; Male; Mice; Mice, Inbred Strains; Mixed Function Oxygenases; Morphine Derivatives; NADPH-Ferrihemoprotein Reductase; Nitrophenols; Oxidoreductases; Phenobarbital | 1975 |
Effects of activators in vitro on rabbit lung and liver microsomal UDP-glucuronyltransferase activity.
Topics: Animals; Biotransformation; Detergents; Drug Interactions; Enzyme Activation; Glucuronosyltransferase; Hexosyltransferases; In Vitro Techniques; Lung; Microsomes; Microsomes, Liver; Nitrophenols; Phenobarbital; Phenols; Proteins; Rabbits | 1975 |
Application of A. C.-polarography in a study of p-nitroanisole metabolism and its kinetic properties.
Topics: Animals; Anisoles; Catechols; Dealkylation; Hydroxylation; In Vitro Techniques; Kinetics; Male; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Nitrophenols; Phenobarbital; Polarography; Proadifen; Proteins; Rats; Time Factors | 1977 |
The continuous kinetic determination of p-nitroanisole O-demethylation in hemoglobin-free perfused rat liver.
Topics: Animals; Anisoles; Carbon Monoxide; Dealkylation; Female; Glucose; Glucuronates; Hemoglobins; In Vitro Techniques; Kinetics; Lactates; Liver; Microsomes, Liver; Nitroanisole O-Demethylase; Nitrophenols; Oxygen Consumption; Perfusion; Phenobarbital; Rats; Sulfates; Time Factors | 1977 |
Oxidative and conjugative metabolism of p-nitroanisole and p-nitrophenol in isolated rat liver cells.
Topics: Alprenolol; Animals; Anisoles; Ethanol; Glucuronates; Liver; Male; Microsomes, Liver; Nitrophenols; Oxidation-Reduction; Phenobarbital; Pyrazoles; Rats; Rotenone; Sulfates; Vitamin K | 1976 |
Drug metabolizing function of isolated perfused liver.
Topics: Animals; Bile; Ethionine; Hexobarbital; Indocyanine Green; Liver; Male; Nitrophenols; Perfusion; Phenobarbital; Rats; Sulfobromophthalein | 1975 |
Inhibition of protein synthesis increases the transcription of the phenobarbital-inducible CYP2H1 and CYP2H2 genes in chick embryo hepatocytes.
Topics: Animals; Base Sequence; Chick Embryo; Cycloheximide; Gene Expression; Liver; Molecular Sequence Data; Nitrophenols; Oligodeoxyribonucleotides; Phenobarbital; Protein Synthesis Inhibitors; RNA, Messenger; Structure-Activity Relationship; Transcription, Genetic | 1992 |
Drug metabolism in Octodon degus: low inductive effect of phenobarbital.
Topics: Aminopyrine N-Demethylase; Aniline Compounds; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Enzyme Induction; Glucuronates; Glucuronosyltransferase; Hydroxylation; Male; Microsomes, Liver; Morphine; Nitrophenols; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains; Rodentia; Steroid Hydroxylases | 1990 |
Ethanol increases cytochromes P450IIE, IIB1/2, and IIIA in cultured rat hepatocytes.
Topics: Acetaminophen; Animals; Cells, Cultured; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Dexamethasone; Ethanol; Hydroxylation; Liver; Male; Nitrophenols; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Troleandomycin | 1991 |
Species difference in codeine uridine diphosphate-glucuronyltransferase activity of liver microsomes.
Topics: Animals; Biphenyl Compounds; Codeine; Enzyme Induction; Glucuronosyltransferase; Guinea Pigs; In Vitro Techniques; Male; Methylcholanthrene; Mice; Microsomes, Liver; Morphine; Nitrophenols; Phenobarbital; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Substrate Specificity | 1990 |
Deficient induction of sulfobromophthalein conjugating activity by phenobarbital in hamster liver.
Topics: Animals; Cricetinae; Dinitrochlorobenzene; Enzyme Induction; Epoxy Compounds; Glutathione; Glutathione Disulfide; Glutathione Transferase; Liver; Male; Mesocricetus; Nitrophenols; Phenobarbital; Sulfobromophthalein | 1987 |
Microsomal metabolism of the carcinogen, N-2-fluorenyl-acetamide, by the mammary gland and liver of female rats. II. Glucuronidation of ring- and N-hydroxylated metabolites of N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Animals; Benzoflavones; beta-Naphthoflavone; Carbon Radioisotopes; Female; Glucuronates; Glucuronosyltransferase; Hydroxylation; In Vitro Techniques; Lactation; Mammary Glands, Animal; Microsomes; Microsomes, Liver; Nitrophenols; Phenobarbital; Pregnancy; Rats; Rats, Inbred Strains | 1985 |
Influence of pregnancy on the hepatic metabolism of parathion.
Topics: Animals; Female; Gestational Age; In Vitro Techniques; Liver; Mice; Mice, Inbred ICR; Nitrophenols; Paraoxon; Parathion; Perfusion; Phenobarbital; Pregnancy; Pregnancy, Animal | 1986 |
Effects of phenobarbital and 3-methylcholanthrene on substrate specificity of rat liver microsomal UDP-glucuronyltransferase.
Topics: Ammonium Sulfate; Animals; Bilirubin; Chemical Precipitation; Chloramphenicol; Cycloheximide; Deoxycholic Acid; Enzyme Activation; Enzyme Induction; Glucuronosyltransferase; Hexosyltransferases; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Naphthols; Nitrophenols; Phenobarbital; Rats; Structure-Activity Relationship; Surface-Active Agents; Trypsin | 1973 |
Enhancement of microsomal drug hydroxylation and glucuronidation in rat liver by phenobarbital and 3-methylcholanthrene in combination.
Topics: Animals; Anisoles; Benzopyrenes; Cetylpyridinium; Coumarins; Culture Media; Digitonin; Drug Synergism; Enzyme Induction; Glucuronosyltransferase; Hexosyltransferases; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Nitrophenols; Oxygenases; Phenobarbital; Rats; Stimulation, Chemical; Trypsin | 1974 |
A comparative study on drug hydroxylation and glucuronidation in liver microsomes of phenobarbital and 3-methylcholanthrene treated rats.
Topics: Animals; Anisoles; Cetylpyridinium; Coumarins; Cytochrome P-450 Enzyme System; Digitonin; Drug Combinations; Enzyme Induction; Glucuronates; Glucuronosyltransferase; Hydroxylation; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Nitro Compounds; Nitrophenols; Oxidoreductases; Phenobarbital; Phospholipases; Proteins; Stimulation, Chemical; Thiocyanates; Trypsin | 1974 |
Drug metabolism in Gunn rats: inability to increase bilirubin glucuronidation by phenobarbital treatment.
Topics: Animals; Bilirubin; Cattle; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Duodenum; Female; Glucosyltransferases; Glucuronates; Glucuronosyltransferase; In Vitro Techniques; Liver; Methyltransferases; Microsomes, Liver; Mixed Function Oxygenases; Nitro Compounds; Nitrophenols; Organ Size; Pancreas; Phenobarbital; Proteins; Rats; Rats, Inbred Strains; Species Specificity; Spectrophotometry; Trypsin | 1974 |
[Studies on microsomal hydroxylation of naphthalene].
Topics: Animals; Chromatography, Thin Layer; DDT; Enzyme Induction; Fluorometry; Kinetics; Liver; Mice; Microsomes; Mixed Function Oxygenases; Naphthalenes; Nitrophenols; Phenobarbital; Stimulation, Chemical | 1969 |
Studies on plasma membranes. XV. A sex difference in alkaline phosphatase activities of plasma membranes isolated from rat liver.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Calcium; Carcinogens; Carcinoma, Hepatocellular; Castration; Cell Membrane; Cholesterol; Edetic Acid; Estrone; Female; Glycerophosphates; Liver; Liver Neoplasms; Magnesium; Male; Neoplasms, Experimental; Nitrophenols; Phenobarbital; Potassium; Rats; Sex Factors; Testosterone; Zinc | 1971 |
The inhibition of alkaline phosphatase by periodate and permanganate.
Topics: Alkaline Phosphatase; Binding Sites; Binding, Competitive; Buffers; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Nitrophenols; Oxidation-Reduction; Periodic Acid; Phenobarbital; Phosphates; Potassium Permanganate; Protein Binding; Spectrophotometry; Time Factors; Tromethamine | 1974 |
Studies on the metabolism of diethyl 4-nitrophenyl phosphorothionate (parathion) in vitro.
Topics: Animals; Benzopyrenes; Carbon Monoxide; Chromatography, Thin Layer; Enzymes; Female; Guinea Pigs; In Vitro Techniques; Liver; Male; Mice; Microsomes; NADP; Nitrogen; Nitrophenols; Oxygen; Parathion; Phenobarbital; Phosphates; Phosphorus Isotopes; Rats | 1967 |
Histochemical demonstration of enzymes related to NADPH-dependent hydroxylating systems in rat liver after phenobarbital treatment.
Topics: Aniline Compounds; Animals; Cytochromes; Electron Transport; Esterases; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Histocytochemistry; Isocitrate Dehydrogenase; Liver; Male; Microsomes, Liver; NADP; Nitrophenols; Oxidoreductases; Phenobarbital; Rats; Stimulation, Chemical | 1969 |
Enzymatic basis of cyclophosphamide activation by hepatic microsomes of the rat.
Topics: Animals; Benzoates; Cyclophosphamide; Cytochromes; Female; Glucose-6-Phosphatase; Hexobarbital; Hydrocortisone; Male; Microsomes, Liver; NADP; Nitrophenols; Oxidoreductases; Phenobarbital; Rats; Sex Factors; Testosterone | 1970 |
The influence of magnesium and some other divalent cations on hepatic microsomal drug metabolism in vitro.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Calcium; Chlorides; Cobalt; Copper; Cytochromes; Edetic Acid; Hexobarbital; In Vitro Techniques; Iron; Magnesium; Male; Manganese; Microsomes, Liver; NADP; Nitrophenols; Phenobarbital; Potassium; Rats; Strontium; Sulfates; Zinc; Zoxazolamine | 1970 |
Effect of phenobarbital and chlorcyclizine on the development of atheromatosis in the cholesterol-fed rabbit.
Topics: Animals; Anisoles; Aorta; Arteriosclerosis; Body Weight; Carbon Isotopes; Cholesterol; Dealkylation; Diet, Atherogenic; Enzyme Activation; Histamine H1 Antagonists; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Nitrophenols; Organ Size; Phenobarbital; Phospholipids; Piperazines; Proteins; Rabbits; Testosterone; Time Factors | 1970 |
Effect of caffeine on hepatic microsomal cytochrome P-450.
Topics: Acetanilides; Adrenalectomy; Animals; Anisoles; Caffeine; Cytochromes; Enzyme Induction; Hydrogen-Ion Concentration; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; NADP; Nitriles; Nitrophenols; Oxidoreductases; Phenobarbital; Rats; Spectrophotometry; Sulfites; Time Factors | 1970 |
Influence of phenobarbital treatment on p-nitrophenol and bilirubin glucuronidation in Wistar rat, Gunn rat and cat.
Topics: Animals; Bilirubin; Cats; Glucuronates; Kinetics; Male; Microsomes, Liver; Nitrophenols; Phenobarbital; Proteins; Rats; Surface-Active Agents; Vibration | 1972 |
Enhancement of hepatic detoxification enzyme activity by dietary mercuric acetate.
Topics: Acetates; Animals; Anisoles; Body Weight; Diet; Dose-Response Relationship, Drug; Drug Synergism; Feeding Behavior; Female; Liver; Mercury; Microsomes, Liver; Nitro Compounds; Nitrophenols; Phenobarbital; Phenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) Ester; Rats | 1973 |
Effect of phenobarbital on the restoration of impaired drug metabolism in carbon tetrachloride-induced liver damage.
Topics: Animals; Body Weight; Carbon Tetrachloride Poisoning; Clinical Enzyme Tests; Cytochromes; Enzyme Activation; Hexobarbital; Injections, Subcutaneous; Liver; Liver Cirrhosis, Experimental; Male; Nitrophenols; Organ Size; Phenobarbital; Rats; Time Factors | 1971 |
Variable effect of phenobarbital treatment of mice on hepatic UDP-glucuronyltransferase activity when judged by slightly different enzyme-assay techniques.
Topics: Animals; Coumarins; Female; Glucuronates; In Vitro Techniques; Liver; Male; Mice; Nitrophenols; Phenobarbital; Phenolphthaleins; Phenols; Stimulation, Chemical; Surface-Active Agents; Transferases; Uracil Nucleotides | 1971 |
Effect of partial liver resection and phenobarbital on the restoration of impaired drug metabolism in carbon tetrachloride induced liver damage.
Topics: Animals; Benzoates; Carbon Tetrachloride Poisoning; Cytochromes; Enzyme Induction; Hepatectomy; Hexobarbital; Hydroxylation; Liver; Liver Cirrhosis; Liver Regeneration; Male; Nitrophenols; Oxidoreductases; Phenobarbital; Rats; Time Factors | 1971 |
Multiplicity and specificity of UDP-glucuronyl transferase. II. Influence of phenobarbital and cholestasis on the activity of glucuronyl transferase and beta-glucuronidase in rat liver.
Topics: Animals; Bilirubin; Cholestasis; Coumarins; Female; Glucuronates; Glucuronidase; Liver; Male; Nitrophenols; Nucleoside Diphosphate Sugars; Phenobarbital; Rats; Spectrophotometry; Stimulation, Chemical; Transferases; Uracil Nucleotides | 1970 |
Biochemical changes in rat liver after administration of carbon disulphide, with particular reference to microsomal changes.
Topics: Adjuvants, Anesthesia; Aniline Compounds; Animals; Anisoles; Blood Proteins; Body Weight; Carbon Disulfide; Carbon Isotopes; Cycloheximide; Cytochromes; DNA; Fasting; Heme; Injections, Intraperitoneal; Leucine; Lipids; Liver; Liver Glycogen; Male; Microsomes, Liver; Mixed Function Oxygenases; Nitro Compounds; Nitrophenols; Organ Size; Phenobarbital; Proadifen; Protein Biosynthesis; Proteins; Rats; RNA; Spectrophotometry; Sucrose; Time Factors | 1969 |
The effect of phenobarbital on the submicrosomal distribution of uridine diphosphate glucuronyltransferase from rat liver.
Topics: Animals; Centrifugation, Density Gradient; Detergents; Enzyme Activation; In Vitro Techniques; Liver; Male; Microsomes, Liver; Nitrophenols; Phenobarbital; Rats; Transferases; Uracil Nucleotides | 1970 |
Effect on newborn rats of perinatal exposure to phenobarbital.
Topics: Acetaminophen; Animals; Animals, Newborn; Antipyrine; Brain; Female; Hexobarbital; Microsomes, Liver; Nitrophenols; Phenobarbital; Pregnancy; Pyrazoles; Rats; Sleep; Spectrophotometry | 1970 |
Long-term variation in basal and phenobarbital-stimulated oxidative drug metabolism in the rat.
Topics: Aminopyrine; Animals; Basal Metabolism; Hexobarbital; In Vitro Techniques; Liver; Male; Nitrophenols; Oxidation-Reduction; Pharmaceutical Preparations; Phenobarbital; Rats; Sleep; Time Factors | 1970 |
Effects of malarial infection on host microsomal drug-metabolizing enzymes.
Topics: Aniline Compounds; Animals; Anisoles; Blood Cell Count; Cytochromes; Endoplasmic Reticulum; Enzyme Induction; Hexobarbital; Malaria; Male; Microsomes, Liver; Morphinans; Nitrophenols; Phenobarbital; Phenylhydrazines; Plasmodium; Proteins; Rats; Reticulocytes; Sleep; Time Factors | 1970 |
Metabolism of drugs during rat liver regeneration.
Topics: Aminopyrine; Aniline Compounds; Animals; Dealkylation; DNA; Glucuronates; Hepatectomy; Hexosyltransferases; Hydroxylation; Laparotomy; Liver; Liver Regeneration; Male; Methylation; Microsomes, Liver; Mitosis; Mixed Function Oxygenases; Nitrophenols; Nucleoside Diphosphate Sugars; Organ Size; Oxidoreductases; Phenobarbital; Rats; Stimulation, Chemical; Time Factors; Uracil Nucleotides | 1970 |
Phenobarbital induction of UDP-glucuronyltransferase in isolated rat hepatocytes.
Topics: Animals; Culture Techniques; Cycloheximide; Enzyme Induction; Liver; Male; Nitrophenols; Phenobarbital; Protein Biosynthesis; Rats; Spectrophotometry; Transferases | 1971 |
Toxicity of carbon tetrachloride and other fasciocidal drugs in sheep and chickens.
Topics: Administration, Oral; Alcohol Oxidoreductases; Animals; Anthelmintics; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chickens; DDT; Fascioliasis; Female; Glutamate Dehydrogenase; Hydrocarbons, Halogenated; Injections, Intraperitoneal; Kidney; Lethal Dose 50; Liver; Male; Muscles; Nitriles; Nitrophenols; Ornithine Carbamoyltransferase; Peritonitis; Phenobarbital; Sheep; Sorbitol | 1971 |
Effect of phenobarbital pretreatment on the metabolism of DDT in the rat and the bovine.
Topics: Acetates; Animals; Biotransformation; Cattle; DDT; Dichlorodiphenyldichloroethane; Female; Hydrocarbons, Halogenated; Liver; Milk; Nitrophenols; Parathion; Phenobarbital; Phosphoric Acids; Rats; Stimulation, Chemical | 1971 |
Factors influencing dimethoate and triethyl phosphate-induced narcosis in rats and mice.
Topics: Age Factors; Anesthesia; Animals; Brain; Cholinesterase Inhibitors; Female; Glycolates; Insecticides; Male; Mice; Nitrophenols; Phenobarbital; Phosphoric Acids; Proadifen; Rats; Reflex; Salivation; Sex Factors | 1971 |
In vitro metabolic studies on propyl p-nitrophenyl ether.
Topics: 1-Propanol; Animals; Carbon Isotopes; Deuterium; Enzyme Induction; Ethers; Guinea Pigs; In Vitro Techniques; Male; Metabolism; Methylcholanthrene; Microsomes, Liver; Nitrophenols; Phenobarbital; Propionates; Rats | 1971 |
The submicrosomal distribution of hepatic uridine diphosphate glucuronyltransferases in the rabbit.
Topics: Animals; Glucosyltransferases; Glucuronates; Liver; Microsomes; Mixed Function Oxygenases; Nitrophenols; Phenobarbital; Phenolphthaleins; Phenols; Rabbits; Uracil Nucleotides | 1968 |
Effects of various chemical agents on drug metabolism and cholesterol biosynthesis.
Topics: Acetanilides; Acetates; Aminopyrine; Animals; Anticholesteremic Agents; Benzopyrenes; Carbon Isotopes; Chloramphenicol; Cholesterol; Depression, Chemical; Drug Synergism; Ethers; Ethylamines; Hexobarbital; Insecticides; Iproniazid; Liver; Male; Mevalonic Acid; Microsomes; Nitrophenols; Phenobarbital; Proadifen; Rabbits; Rats; Sleep; Time Factors | 1968 |
Effects of pyretic drugs on spontaneous EEGs in rabbits with the chronically implanted electrodes.
Topics: Animals; Electrodes; Electroencephalography; Male; Methamphetamine; Nitrophenols; Phenobarbital; Pyrogens; Rabbits | 1968 |
Inhibition of hepatic microsomal enzymes by alkylating agents.
Topics: Aging; Aminopyrine; Animals; Cyclophosphamide; Drug Synergism; Enzyme Induction; Enzymes; Liver; Male; Mechlorethamine; Microsomes; Nitrophenols; Organophosphonates; Oxidoreductases; Phenobarbital; Pipobroman; Rats; Time Factors | 1969 |
Re-evaluation of the influence of sex, age pregnancy, and phenobarbital on the activity of UDP-glucuronyl transferase in rat liver.
Topics: Age Factors; Animals; Animals, Newborn; Bilirubin; Female; Liver; Nitrophenols; Phenobarbital; Pregnancy; Rats; Sex Factors; Transferases | 1969 |
Stimulation of detoxification of O-94-nitrophenyl) phenylphosphonothioate (EPN) by nikethamide and phenobarbital.
Topics: Animals; Biotransformation; Insecticides; Liver; Microsomes; Nikethamide; Nitrophenols; Phenobarbital; Rats | 1966 |
The effects of phenobarbital, 3-methylcholanthrene and benzo(a)pyrene on the hydrolysis of xenobiotics in the rat.
Topics: 2-Acetylaminofluorene; Acetanilides; Amidohydrolases; Animals; Aspirin; Benzo(a)pyrene; Benzopyrenes; Carboxylic Ester Hydrolases; Female; Methylcholanthrene; Microsomes, Liver; Nitrophenols; Phenobarbital; Procaine; Rats; Tissue Distribution | 1983 |
Effects of steroid hormones and xenobiotics on the pubertal development of UDP-glucuronosyltransferase activities towards androsterone and 4-nitrophenol in Wistar rats.
Topics: Androsterone; Animals; Corticosterone; Estradiol; Female; Glucuronosyltransferase; Gonadal Steroid Hormones; Liver; Male; Methylcholanthrene; Milk; Nitrophenols; Phenobarbital; Phenotype; Rats; Rats, Inbred Strains; Sexual Maturation | 1984 |
The effects of phenobarbital, bis-p-nitrophenyl phosphate and disulfiram on the hydrolysis of propanidid in Wistar rats.
Topics: Animals; Carboxylic Ester Hydrolases; Chromatography, High Pressure Liquid; Cytosol; Disulfiram; Dogs; Hydrolysis; Liver; Male; Microsomes, Liver; Nitrophenols; Phenobarbital; Propanidid; Rats; Rats, Inbred Strains; Sleep; Time Factors | 1984 |
Rat liver sulfotransferases: effects of gonadal hormones and other factors on enzyme activities.
Topics: Aging; Androsterone; Animals; Body Weight; Corticosterone; Cytosol; Estradiol; Gonadal Steroid Hormones; Liver; Male; Methylcholanthrene; Nitrophenols; Organ Size; Phenobarbital; Progesterone; Rats; Rats, Inbred Strains; Sulfurtransferases; Testosterone | 1984 |
Glucuronidation and sulfation of p-nitrophenol in isolated rat hepatocyte subpopulations. Effects of phenobarbital and 3-methylcholanthrene pretreatment.
Topics: 4-Aminobenzoic Acid; Animals; Cytochrome P-450 Enzyme System; Glucuronates; In Vitro Techniques; Liver; Male; Methylcholanthrene; Nitrobenzenes; Nitrophenols; Phenobarbital; Rats; Rats, Inbred Strains; Sulfates | 1983 |
Serum lipids and hepatic microsomal enzymes with special reference to serum cholinesterase in Wistar rats.
Topics: Animals; Cholinesterases; Disulfiram; Enzyme Induction; Lipids; Male; Microsomes, Liver; Mixed Function Oxygenases; Nitrophenols; Organophosphorus Compounds; Phenobarbital; Rats; Rats, Inbred Strains | 1984 |
Isoniazid hepatoxicity: the relationship between covalent binding and metabolism in vivo.
Topics: Acetylation; Amidohydrolases; Animals; Biotransformation; Carbon Dioxide; Chemical and Drug Induced Liver Injury; Cobalt; Hydrolysis; Isoniazid; Liver; Male; Microsomes, Liver; Nitrophenols; Organophosphorus Compounds; Phenobarbital; Protein Binding; Rats | 1980 |
Effect of metal salts on UDPglucuronosyltransferase activity of various aglycones in rat liver microsomes in vitro.
Topics: Aminophenols; Animals; Biotransformation; Glucuronates; Glucuronosyltransferase; In Vitro Techniques; Male; Metals; Methylcholanthrene; Microsomes, Liver; Nitrophenols; Phenobarbital; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred Strains | 1980 |
Glucuronide and sulphate conjugation in isolated liver cells from control and phenobarbital- or PCB-treated rats.
Topics: Aminophenols; Animals; Glucuronates; Hymecromone; In Vitro Techniques; Liver; Male; Nitrophenols; Phenobarbital; Polychlorinated Biphenyls; Rats; Sulfates | 1980 |
Postnatal development of mixed-function oxidation and conjugation in hemoglobin-free perfused rat liver.
Topics: Animals; Animals, Newborn; Glucuronosyltransferase; Hemoglobins; In Vitro Techniques; Liver; Liver Glycogen; Microsomes, Liver; Mixed Function Oxygenases; Nitroanisole O-Demethylase; Nitrophenols; Oxidoreductases; Perfusion; Phenobarbital; Rats | 1981 |
Conjugation of p-nitrophenol in the perfused rat liver: the effect of substrate concentration and carbohydrate reserves.
Topics: Animals; Antimetabolites; Carbohydrate Metabolism; Fasting; Female; Flavoproteins; Glucuronosyltransferase; Liver; NAD; Nitroanisole O-Demethylase; Nitrophenols; Phenobarbital; Rats; Sulfates; Sulfurtransferases | 1981 |
Effect of model inducers on cytochrome P450 activities of human hepatocytes in primary culture.
Topics: Adult; Aged; Cells, Cultured; Clofibric Acid; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Ethanol; Female; Humans; Isoenzymes; Liver; Male; Methylcholanthrene; Middle Aged; Nitrophenols; Oxazines; Oxidation-Reduction; Phenobarbital; Safrole; Substrate Specificity; Testosterone | 1995 |
UDP glucuronosyltransferase gene expression is involved in the stimulation of ascorbic acid biosynthesis by xenobiotics in rats.
Topics: Analysis of Variance; Animals; Ascorbic Acid; Base Sequence; Blotting, Northern; Body Weight; Chloramphenicol; Gene Expression Regulation, Enzymologic; Glucuronosyltransferase; Injections, Intraperitoneal; Liver; Methylcholanthrene; Molecular Sequence Data; Nitrophenols; Organ Size; Phenobarbital; Polymerase Chain Reaction; Rats; Rats, Gunn; Rats, Inbred Strains; RNA, Messenger; Time Factors; Xenobiotics | 1993 |
Similarities and differences in the glucuronidation of estradiol and estrone by UDP-glucuronosyltransferase in liver microsomes from male and female rats.
Topics: Animals; Dexamethasone; Estradiol; Estrone; Female; Glucuronates; Glucuronosyltransferase; Hydrogen-Ion Concentration; Hydroxylation; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Nitrophenols; Phenobarbital; Rats; Substrate Specificity; Testosterone | 1996 |
Involvement of CYP2E in 8-hydroxylation of theophylline in mouse hepatic microsomes-difference from its N-demethylations.
Topics: Acetone; Aminoacetonitrile; Aminopyrine; Animals; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fomepizole; Hydroxylation; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Nitrophenols; Oxazines; Phenobarbital; Pregnenolone Carbonitrile; Pyrazoles; Theophylline | 1996 |
Sex differences in biotransformation of the xenobiotic p-nitroanisole in isolated rat hepatocyte under the influence of phenobarbital.
Topics: Animals; Anisoles; Biotransformation; Cells, Cultured; Cytochrome P-450 Enzyme System; Female; Liver; Male; Nitrophenols; Phenobarbital; Rats; Rats, Wistar; Sex Characteristics; Xenobiotics | 1997 |
Identification of theta-class glutathione S-transferase in liver cytosol of the marmoset monkey.
Topics: Animals; Callithrix; Chromatography, Affinity; Clofibric Acid; Cytosol; Dinitrochlorobenzene; Epoxy Compounds; Glutathione Transferase; Humans; Liver; Methyl Chloride; Methylene Chloride; Mice; Mice, Inbred BALB C; Nitrophenols; Phenobarbital; Polychlorinated Dibenzodioxins; Rats; Rats, Wistar; Rifampin; Species Specificity | 2000 |
Chloramphenicol and ampicillin-induced changes in rat hepatic esterase and amidase activities.
Topics: Amidohydrolases; Ampicillin; Animals; Anti-Bacterial Agents; Carboxylic Ester Hydrolases; Chloramphenicol; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Indicators and Reagents; Isoenzymes; Liver; Male; Nitrophenols; Organophosphorus Compounds; Penicillins; Phenobarbital; Protein Synthesis Inhibitors; Proteins; Rats; Rats, Wistar | 2000 |
The role of conjugation in hepatotoxicity of troglitazone in human and porcine hepatocyte cultures.
Topics: Acetaminophen; Animals; Cells, Cultured; Chromans; Dose-Response Relationship, Drug; Hepatocytes; Humans; Nitrophenols; Pentachlorophenol; Phenobarbital; Protein Biosynthesis; Proteins; Swine; Thiazoles; Thiazolidinediones; Troglitazone | 2000 |
Para-nitrophenol glucuronidation and sulfation in rat and human liver slices.
Topics: Animals; beta-Naphthoflavone; Chromatography, High Pressure Liquid; Glucuronates; Humans; In Vitro Techniques; Liver; Male; Nitrophenols; Phenobarbital; Rats; Rats, Wistar; Species Specificity; Sulfates; Time Factors | 2001 |
AN ADAPTIVELY STIMULATED O-DEMETHYLATING SYSTEM IN RAT LIVER MICROSOMES AND ITS KINETIC PROPERTIES.
Topics: Benzopyrenes; Kinetics; Liver; Metabolism; Microsomes; Microsomes, Liver; Nitrobenzenes; Nitrophenols; Pharmacology; Phenobarbital; Rats; Research | 1964 |
Role of metabolism in parathion-induced hepatotoxicity and immunotoxicity.
Topics: Alanine Transaminase; Animals; Antibody-Producing Cells; Aspartate Aminotransferases; Biotransformation; Cytochrome P-450 CYP2B1; Female; Glutathione; Insecticides; Liver; Mice; Mice, Inbred BALB C; Microsomes, Liver; Nitrophenols; Paraoxon; Parathion; Phenobarbital; Rats; Rats, Sprague-Dawley; Sheep; Spleen | 2005 |
On the mechanism of hepatocarcinogenesis of benzodiazepines: evidence that diazepam and oxazepam are CYP2B inducers in rats, and both CYP2B and CYP4A inducers in mice.
Topics: Animals; Benzodiazepines; Blotting, Western; Body Weight; Carcinogens; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Diazepam; Hypnotics and Sedatives; Immunohistochemistry; Isoenzymes; Lauric Acids; Liver Neoplasms; Male; Mice; Microsomes, Liver; Nitrophenols; Organ Size; Oxazepam; Phenobarbital; Rats; Rats, Sprague-Dawley | 2006 |
UDP-glucuronosyltransferase activities in human liver microsomes and in some laboratory animal species.
Topics: Adolescent; Aged; Animals; Camphanes; Chloramphenicol; Eugenol; Female; Glucuronides; Glucuronosyltransferase; Humans; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Middle Aged; Nitrophenols; Phenobarbital; Rats; Rats, Sprague-Dawley; Rats, Wistar; Species Specificity; Swine; Uridine Diphosphate | 1981 |
Effects of iron overload, an iron chelator and a T-Type calcium channel blocker on cardiac mitochondrial biogenesis and mitochondrial dynamics in thalassemic mice.
Topics: Aminophylline; Animals; Apoptosis; Atropine; Blood Pressure; Calcium Channel Blockers; Calcium Channels, T-Type; Deferiprone; Dihydropyridines; Drug Combinations; Heart; Heart Rate; Iron; Iron Chelating Agents; Iron Overload; Male; Malondialdehyde; Mice; Mitochondria; Myocardium; Nitroglycerin; Nitrophenols; Organelle Biogenesis; Organophosphorus Compounds; Oxidative Phosphorylation; Papaverine; Phenobarbital; Pyridones; Signal Transduction; Thalassemia | 2017 |